grey red grey grey _h_478 blue GADD45A grey blue _h_5991 not (E2F4_DP2_p107_p130_nucleus_DP2_E2F4_p130 or E2F4_DP2_p107_p130_nucleus_DP2_p107_E2F4) grey red grey grey blue _h_1391 Myb_PAX5_LEF1_nucleus red grey grey red grey _h_4281 blue BMP7_BMPR2_BMPR1A_1B_1act_integral_to_membrane and SMAD1_cytoplasm red blue _h_2434_10 ((EGFR_EGFR_1act_integral_to_membrane_v1 or EGFR_EGFR_EGF_EGF_GRB2_GAB1_1act_integral_to_membrane_v1) and ( not (EGFR_EGFR_1ina_integral_to_membrane or EGFR_EGFR_EGF_EGF_GRB2_GAB1_1ina_integral_to_membrane))) blue _h_4285 E2F3_DP_TFE3_nucleus blue _h_4284 (Erk1_1O_1act_1O_cytoplasm or Erk2_1O_1O_1act_cytoplasm) blue _h_4287 (((SP1 or STAT5A_B__dimer__1act_nucleus) or STAT5A__dimer__active_1act_nucleus_v2) or STAT5B__dimer__1act_nucleus) _h_4286 blue Borealin and INCENP and INCENP_v1 grey red red _h_4460 blue MYC_Max_nucleus_v2 and SPT3_nucleus and STAF65G_nucleus and TAF12_nucleus and TAF9_nucleus and TRRAP_GCN5_nucleus and core_mediator_complex_nucleus red grey grey red blue _h_2434_14 ((EGFR_EGFR_1act_integral_to_membrane_v1 or EGFR_EGFR_EGF_EGF_GRB2_GAB1_1act_integral_to_membrane_v1) and ( not (EGFR_EGFR_1ina_integral_to_membrane or EGFR_EGFR_EGF_EGF_GRB2_GAB1_1ina_integral_to_membrane))) grey red red grey grey _h_2979 blue TGFB_TGFBR2_betaglycan_1act_integral_to_membrane and not BAMBI_TGFBR1 _h_2978 blue alphav_beta3_Integrin grey grey blue _h_2971 Fra1_p300_JUNB_JUND_SP1_1act_nucleus blue _h_2970 Fra1_JUN_1act_nucleus blue _h_2973 SPHK2_1act _h_2972 blue beta_catenin_nucleus blue _h_2975 ATF2_JUNB_1act_nucleus blue _h_2974 HIF1A_ARNT_nucleus _h_2977 blue nectin_3_dimer__I_afadin_I_afadin_Necl_5_dimer__cell_cell_junction blue _h_2976 PLK1_1O_1act grey _h_4759 blue RelA blue _h_4758 PITPNA_1act blue _h_4753 FOXM1C_SP1_1act_nucleus grey _h_4751 blue IL2_IL2R_alpha_beta_gamma_JAK1_LCK_JAK3_SHC_1act_integral_to_membrane red _h_4757 blue GMCSF_GMR_alpha_CSF2RB_JAK2__dimer__YWHAZ_SHC_1act_integral_to_membrane blue _h_4755 (((((PKC_delta_1act_plasma_membrane or RAS_family_GTP_1act_H_RAS_isoform_1_GTP_v1) or RAS_family_GTP_1act_N_RAS_GTP_v1) or RAS_family_GTP_1act_plasma_membrane_H_RAS_isoform_1_GTP_v1) or RAS_family_GTP_1act_plasma_membrane_N_RAS_GTP_v1) or RRas_GTP_1act_focal_adhesion) _h_4754 blue alphaM_beta2_Integrin_integral_to_membrane red red grey red red red _h_4648 blue SPA_1_1act_cell_leading_edge _h_4630 blue TCF4_beta_catenin_1act_nucleus red grey blue _h_4634 E_cadherin_Ca2__beta_catenin_alpha_catenin_p120_catenin_cell_cell_junction_v1 _h_4635 blue PPP1CA and Smad7 blue _h_4636 IFN_gamma_IFN_gammaR_JAK1_JAK1_JAK2_JAK2_1act blue _h_4637 MYC_Max_nucleus_v2 blue _h_4638 uPA_uPAR_1act_plasma_membrane_v2 grey grey grey _h_723 blue CXCR2_integral_to_membrane red blue _h_430 Tie2_Ang1_1act or Tie2_Ang2 grey red red grey grey grey blue _h_726 PLK3_1act_1p red red blue _h_725 ARF1_GTP_1act_plasma_membrane or Phosphatidic_acid or RAC1_GTP_1act_plasma_membrane grey red grey grey grey grey grey red blue _h_222 gamma_secretase blue _h_223 RAB5_GTP_1act_v2 _h_220 blue netrin_1_DCC_1act_integral_to_membrane _h_221 blue ErbB2_integral_to_membrane and HB_EGF_extracellular_region blue _h_226 Gab1 or Importin_beta blue _h_227 Src_1act_1O grey red grey red blue _h_2944_4 not E_cadherin_cytoplasm and (MAPK_14 or p120ctn) red red grey red grey grey blue _h_4288 PI3K_1act_plasma_membrane_v2 or PI3K_beta_1act_plasma_membrane or PI3K_delta_1act_plasma_membrane or PI3K_gamma_p101_1act_plasma_membrane or PI3K_gamma_p84_1act_plasma_membrane or PI3K_p110_alpha_p55_gamma_1act_plasma_membrane or PI3K_p110_alpha_p85_beta_1act_plasma_membrane or PI3K_p110_beta_p55_gamma_1act_plasma_membrane or PI3K_p110_beta_p85_beta_1act_plasma_membrane or PI3K_p110_delta_p55_gamma_1act_plasma_membrane or PI3K_p110_delta_p85_beta_1act_plasma_membrane _h_4493_1 blue TSC1_TSC2_14_3_3_family_1ina_TSC2_TSC1_YWHAS _h_1450_1 blue Src_1_nucleus red grey grey grey _h_1450_2 blue Src_1_nucleus grey red red red _h_6452 blue Src_1act_1O blue _h_6453 Caspase_3_1act _h_6450 blue CHK1_2O_1act_nucleus red grey grey grey _h_186_1 blue KLHL12_Cul3 grey grey grey _h_6229_5 blue KPNA1 and YWHAB_cytoplasm red grey grey _h_3367 blue FAS__trimer__integral_to_membrane blue _h_3365 Akt1_1O_1act_1O_1O_plasma_membrane blue _h_3364 ( not HEY1_nucleus) blue _h_3363 PI3K_1act_plasma_membrane_v2 or PI3K_beta_1act_plasma_membrane or PI3K_delta_1act_plasma_membrane or PI3K_p110_alpha_p55_gamma_1act_plasma_membrane or PI3K_p110_alpha_p85_beta_1act_plasma_membrane or PI3K_p110_beta_p55_gamma_1act_plasma_membrane or PI3K_p110_beta_p85_beta_1act_plasma_membrane or PI3K_p110_delta_p55_gamma_1act_plasma_membrane or PI3K_p110_delta_p85_beta_1act_plasma_membrane or PI_3_4_5_P3_plasma_membrane grey blue _h_3360 (NICD_YY1_1act_nucleus and ( not (ENO1 or MYCBP))) blue _h_5901 p53__tetramer__nucleus_v2 blue _h_5900 not PAT1 grey grey blue _h_5905 IL12_IL12R_TYK2_JAK2_1act_integral_to_membrane grey blue _h_5907 (p53_nucleus and ( not cortisol_GR_alpha__dimer__nucleus_v1)) _h_5906 blue RACK1 and Src_1act_1O red grey grey grey _h_1393 blue VEGFA189 red _h_3210_1 blue EphB2_integral_to_membrane _h_3210_2 blue EPHB1_integral_to_membrane red _h_3323 blue Hck grey grey grey grey _h_171_1 blue (NICD_1O_nucleus and SHARP_RBPJ_nucleus) _h_171_2 blue NICD_1O_nucleus and SHARP_RBPJ_nucleus _h_458 blue (RAB5_GDP_1ina and (((Eps8_RNTRE or PDGF_BB_PDGFRB__dimer__1act_integral_to_membrane_v1) or RIN1_1act) or RIN2_1act)) _h_5283 blue IL6_IL6RA_gp130__dimer__JAK1_JAK1_LMO4_1act_integral_to_membrane_v2 grey grey red red red grey red red blue _h_5280 (E2F1_DP_nucleus_v4 and ( not ((RB1_E2F1_3_DP_nucleus_v1_DP1_E2F1_RB1_2O or RB1_E2F1_3_DP_nucleus_v1_DP1_E2F3_RB1_2O) or RB1_E2F1_3_DP_nucleus_v1_DP1_RB1_2O_E2F2))) red grey grey grey grey red grey grey grey grey red grey red _h_4297_1 blue PDGF_BB_PDGFRB__dimer__GAB1_N_WASP_1act_integral_to_membrane grey red blue _h_2368 CK1_gamma_1act_membrane_raft _h_2369 blue PKC_isoenzymes and not Syndecan_4 red _h_2364 blue GATA4_1act_nucleus _h_2366 blue RPA_ATR_ATRIP_RAD17_RFC2_5_9_1_1_TopBP1_CEP164_TIMELESS_TIPIN_1act_nucleus grey red red red blue _h_2363 CaM_Ca2__CAMKII_1act_CaM_CAMKIIB_Ca2__v1 or CaM_Ca2__CAMKII_1act_CaM_CAMKIID_Ca2__v1 or CaM_Ca2__CAMKII_1act_CaM_CaMK_Ca2__v1 or CaM_Ca2__CAMKII_1act_CaM_CaMK_II_delta_B_Ca2__v1 or PKC_delta_1O_1act red grey red grey blue _h_376 p53__tetramer__nucleus_v2 grey grey grey grey grey _h_2607 blue ICAM1 grey grey grey grey grey red grey _h_2108 blue RACO_1_1act blue _h_2109 E4ICDs_1act_5O_cytoplasm or E4ICDs_CYT2_1act_4O_cytoplasm blue _h_2100 ATM_1act _h_2101 blue Caspase_6_1act blue _h_2102 S1P_S1P3_Gi or VEGFR1_homodimer_VEGFA_homodimer_1act_plasma_membrane grey blue _h_2104 (FOXM1B_nucleus and ( not FOXM1B_p14ARF_1ina_nucleolus)) blue _h_2105 TAp73a__tetramer__nucleus_v3 _h_2106 blue GRB2_SOS1_cytoplasm blue _h_3407 not MYC_Max_MIZ_1_nucleus and (MIZ_1_nucleus or SP1_3_nucleus) grey _h_399_1 blue SMAD5_2O_1act_cytoplasm grey blue _h_4367 ((JUNB_Fra1_NFAT1_c_4_1act_nucleus_NFAT1_1O_7O_2s_1act_nucleus_Fra1_JUNB or JUNB_Fra1_NFAT1_c_4_1act_nucleus_NFAT4_1act_nucleus_Fra1_JUNB) or JUNB_Fra1_NFAT1_c_4_1act_nucleus_NFATc_1act_nucleus_Fra1_JUNB) red grey _h_3263_36 blue FGFR1b_FGF10_1act red _h_3263_34 blue FGFR1b_FGF1_1act red _h_3263_32 blue FGFR1c_FGF2_1act _h_3263_33 blue FGFR1b_FGF3_1act grey _h_3263_31 blue E_cadherin_Ca2__beta_catenin_alpha_catenin_p120_catenin_cell_cell_junction_v1 grey _h_3263_38 blue FGFR1c_FGF6_1act red grey _h_4596_2 blue CABIN1 and MEF2D_1act_nucleus and NFAT1_1O_4O_2s_1act_nucleus red grey grey _h_3161 blue TNFR1A_BAG4_v2 red blue _h_807_79 FASLG_FAS__trimer__Src_Syk_1act_integral_to_membrane or TRAIL__trimer__extracellular_region blue _h_4361 TAp73b__tetramer__nucleus grey _h_3908_1 blue FAK_Src_Yes_Fyn_p130_CAS_CRK_1act_focal_adhesion_Crk_Fyn_1O_1act_p130Cas_1O_FAK_6O_1act _h_3908_2 blue FAK_Src_Yes_Fyn_p130_CAS_CRK_1act_focal_adhesion_Src_1act_1O_Crk_p130Cas_1O_FAK_6O_1act _h_5496 blue Type_I_PKA_1act_cell_leading_edge grey red blue _h_2098 ((SMAD2_3_SMAD4_SP1_SMAD2_2O_1act_SP1_SMAD4 or SMAD2_3_SMAD4_SP1_SP1_Smad3_2O_1act_SMAD4) and ( not (SMAD2_3_SMAD4_MYC_Max_MIZ_1_nucleus_MYC_Smad3_2O_1act_Max_SMAD4_MIZ_1 or SMAD2_3_SMAD4_MYC_Max_MIZ_1_nucleus_SMAD2_2O_1act_MYC_Max_SMAD4_MIZ_1))) red red red grey grey red red grey red grey grey blue _h_5843 GTF3A or STAT6__dimer__1act_nucleus_v1 grey blue _h_4861 MAP3Ks_1act red grey blue _h_4860 Erk2_1O_1O_1act or p38_alpha_1O_1O_1act_v2 _h_469_2 blue CBP grey red blue _h_5899_44 ErbB2_ErbB3_neuregulin_1_beta_1act_integral_to_membrane_v1 _h_5347 blue HEY2_nucleus grey blue _h_5345 ILK_1act_1p _h_5344 blue FZD1_integral_to_membrane and LRP6_integral_to_membrane _h_5343 blue IL3_IL3RA_CSF2RB__dodecamer__JAK2_JAK2_SHP2_1act_integral_to_membrane blue _h_5342 not MYC_Max_nucleus_v4 blue _h_5341 CD45 or CD45_integral_to_membrane red _h_4865 blue (GTP_v1 and (((((((((AGTR1_1act_integral_to_membrane or ARAP3_integral_to_membrane) or ARFGEP100_1act_plasma_membrane) or ARNO_1act_integral_to_membrane) or EGFR_EGFR_EGF_EGF_ARFGEP100_integral_to_membrane) or GRP1_1act_plasma_membrane) or HGF_MET) or IPCEF1_ARNO_plasma_membrane) or Src_1act_1O) or TSHR_1act_integral_to_membrane)) red red grey _h_5348 blue MYD88 grey _h_1456 blue DNER_integral_to_membrane blue _h_6335 p53__tetramer__nucleus_v2 blue _h_1454 JUN_ATF2_1act_nucleus grey _h_1452 blue Gi_family_GDP_G_beta_gamma_1ina and SDF1_CXCR4_1act_integral_to_membrane _h_1451 blue E2_ERA__dimer__1act_nucleus _h_4752 blue TRAF6 grey grey _h_4866 blue PDE6_1act_v1 red blue _h_6339 (((Elf1 or STAT5A_B__dimer__1act_nucleus) or STAT5A__dimer__active_1act_nucleus_v2) or STAT5B__dimer__1act_nucleus) grey grey red red red grey red grey blue _h_5800 not MYC_Max_nucleus_v4 grey grey grey red red _h_2746 blue BAMBI and BMP2_4__homodimer__extracellular_region and BMPR1A_1B__homodimer__integral_to_membrane and BMPR2__homodimer__1act_integral_to_membrane and RGM_family red red blue _h_1036_131 Arf6_GTP_1act or Arf6_GTP_1act_plasma_membrane grey blue _h_5051_4 (RAS_family_GTP_1act_plasma_membrane_H_RAS_isoform_1_GTP_v1 or RAS_family_GTP_1act_plasma_membrane_N_RAS_GTP_v1) _h_238_6 blue alpha6_beta1_Integrin grey grey red red _h_238_3 blue alpha6_beta1_Integrin grey _h_238_1 blue Laminin_4 blue _h_5051_49 (RAS_family_GTP_1act_plasma_membrane_H_RAS_isoform_1_GTP_v1 or RAS_family_GTP_1act_plasma_membrane_N_RAS_GTP_v1) blue _h_3212 Blk_1O_1act_plasma_membrane or Fgr_1act_1O_plasma_membrane or Fyn_1act_1O_plasma_membrane or Hck_1act_1O_plasma_membrane or Jak2_1act_1O or LYN_1O_1act_plasma_membrane or Lck_1O_1act_plasma_membrane or PDGF_BB_PDGFRB__dimer__1act_integral_to_membrane_v1 or Src_1O_1act_plasma_membrane or Yes_1act_1O_plasma_membrane _h_238_8 blue alpha6_beta1_Integrin blue _h_2786 p38alpha_beta_MAPKAPK2_1act_MAPKAPK2_4O_1O_p38_alpha_1O_1O_1act_v2 or p38alpha_beta_MAPKAPK2_1act_MAPKAPK2_4O_1O_p38_beta_1O_1O_1act grey grey grey blue _h_1948 Ca2__cytoplasm or DAG_v2 _h_4426_1 blue FAK_Src_Yes_Fyn_1act_focal_adhesion_v2_Fyn_1O_1act_FAK_6O_1act grey grey _h_5734 blue alphaM_beta2_Integrin_1act_integral_to_membrane grey blue _h_5732 FOXM1B_nucleus red red grey blue _h_4696_2 (DHT_plasma_membrane or testosterone_plasma_membrane) blue _h_4696_1 (DHT_plasma_membrane or testosterone_plasma_membrane) blue _h_5738 TGFB1_TGF_beta_receptor_Type_II_1act _h_5703_2 blue PDGF_BB_PDGFRB__dimer__1act_integral_to_membrane_v1 grey _h_2003_2 blue Syndecan_4 red red red grey grey _h_410 blue alphav_beta3_Integrin_1act_integral_to_membrane grey grey grey red red grey grey grey grey red grey red grey red red red grey red red _h_2003_4 blue Syndecan_4 blue _h_2944_53 not E_cadherin_cytoplasm and (MAPK_14 or p120ctn) blue _h_2944_52 not E_cadherin_cytoplasm and (MAPK_14 or p120ctn) grey blue _h_2944_50 not E_cadherin_cytoplasm and (MAPK_14 or p120ctn) blue _h_2944_57 not E_cadherin_cytoplasm and (MAPK_14 or p120ctn) blue _h_2944_56 not E_cadherin_cytoplasm and (MAPK_14 or p120ctn) blue _h_2944_55 not E_cadherin_cytoplasm and (MAPK_14 or p120ctn) blue _h_2944_54 not E_cadherin_cytoplasm and (MAPK_14 or p120ctn) grey blue _h_2944_59 not E_cadherin_cytoplasm and (MAPK_14 or p120ctn) grey grey red _h_314 blue Ephexin and (Fyn_1O_1act or LYN_1act_1O or Lck_1O_1act or Src_1act_1O) blue _h_5709 E_cadherin_Ca2__beta_catenin_alpha_catenin_p120_catenin_cell_cell_junction_v1 red grey red red red red grey grey grey grey red grey _h_3362 blue SMAD4_cytoplasm and SMAD6 grey red grey _h_1994 blue Tumstatin red _h_1611_1 blue GTP_v1 and (EGFR_EGFR_EGF_EGF_GRB2_SOS1_1act_endosome_v1 or EGFR_EGFR_EGF_EGF_p46_SHC_GRB2_SOS1_1act_endosome or EGFR_EGFR_EGF_EGF_p52_SHC_GRB2_SOS1_1act_endosome_v1 or Ephrin_B_EPHB2_RasGAP_1act_integral_to_membrane) grey _h_1953 blue (IKK_beta_cytoplasm and NEMO_1u_cytoplasm) blue _h_4631 PDGF_BB_PDGFRB__dimer__GAB1_N_WASP_NCK1_2_1act_integral_to_membrane_v1_PDGFRB_11O_NCK1_PDGFB_v1_N_WASP_1act_Gab1_1O or PDGF_BB_PDGFRB__dimer__GAB1_N_WASP_NCK1_2_1act_integral_to_membrane_v1_PDGFRB_11O_NCK2_PDGFB_v1_N_WASP_1act_Gab1_1O or WAVE2_Nap1_Sra1_AbI1_HSPC300_1act_cell_leading_edge or WAVE2_Nap1_Sra1_AbI1_HSPC300_1act_cell_leading_edge_v1 blue _h_5794 (((BRM_CEBP_nucleus_CEBPA_BRM or BRM_CEBP_nucleus_CEBPB_BRM) or BRM_CEBP_nucleus_CEBPD_BRM) or PIM1_p100_Myb_nucleus) red red blue _h_3114 PLK1_1O_1act grey blue _h_3130_8 CRIPTO_GPC1_1act_plasma_membrane blue _h_3130_5 CRIPTO_GPC1_1act_plasma_membrane blue _h_3130_4 CRIPTO_GPC1_1act_plasma_membrane blue _h_3130_7 CRIPTO_GPC1_1act_plasma_membrane red grey grey red _h_4090 blue HMGB1 _h_4747 blue Phosphatidic_acid and mTOR_GBL_PRAS40_DEPTOR_1ina _h_417 blue HGF_dimer__MET_dimer__1act_integral_to_membrane_v1 grey grey grey grey blue _h_4639 GRK2 grey red grey grey blue _h_4096 (ETS1 or HIF2A_ARNT_nucleus_v3) grey grey grey grey grey grey grey grey grey grey red red red red red red grey grey grey blue _h_216 Par6_PKC_zeta_v1 red red grey red red red grey grey _h_1246_2 blue ((CTHRC1_trimer_ and FZD5_integral_to_membrane) and ROR2_integral_to_membrane) red grey grey red blue _h_3196 E2F1_DP_nucleus_v1 _h_3197 blue HDAC4_1O_1O_cytoplasm grey blue _h_3191 IFN_gamma_IFN_gammaR_JAK1_JAK1_JAK2_JAK2_1act or IL4_IL4R_JAK1_IL2R_gamma_JAK3_1act_integral_to_membrane _h_3193 blue 9cRA_extracellular_region red _h_3198 blue Necl_5_dimer__integral_to_membrane _h_3199 blue netrin_1_extracellular_region red grey blue _h_3973_4 LPA_LPA2 or LPA_LPA3 red blue _h_3973_3 LPA_LPA2 or LPA_LPA3 grey grey grey grey grey blue _h_5135 FOXA2_nucleus_v1 or HNF4_nucleus or SP1_3_nucleus blue _h_5136 dNp63b__tetramer__nucleus grey grey _h_5132 blue MYOD_TCF3 grey blue _h_1507 CD45 or CD45_integral_to_membrane blue _h_1738 SMAD3_SMAD4_GATA3_1act_nucleus grey _h_6108 blue Osteopontin red _h_1732 blue BRCA1_CtBP_CtIP grey blue _h_6106 STAT3__dimer___1act_nucleus blue _h_1731 ILK_1act_1p blue _h_1736 Exportin_1 _h_400 blue cortisol_GR_alpha__dimer__nucleus_v1 _h_6102 blue TGFBR2 blue _h_6103 (E2F1_DP_nucleus_v4 and ( not RB1_E2F1_DP_nucleus)) grey _h_3998 blue JUN_Cbp blue _h_3999 Myb_nucleus red blue _h_3996 MRN_complex_ATM_MDC1_H2AX_RNF8_53BP1_1act_site_of_double_strand_break blue _h_3997 E_cadherin_Ca2__beta_catenin_alpha_catenin_p120_catenin_cell_cell_junction_v1 or E_cadherin_Ca2__beta_catenin_gamma_catenin_alpha_catenin_p120_catenin_cell_cell_junction_v2 _h_3990 blue IL2_IL2R_alpha_beta_gamma_JAK1_LCK_JAK3_1act_integral_to_membrane grey blue _h_3992 SIRT3 blue _h_3993 ((((((((((((((((((Btk_1act_2O_plasma_membrane or CDC42_GTP_1act) or EPO_EPOR__dimer__LYN) or ETA_receptor_Endothelin_1_Gq_GTP_1act_integral_to_membrane) or MEKK1_1act) or MKK4_1O_1O_1act) or MKK4_1O_1O_1act_cytoplasm) or MKK4_1O_1act) or MKK4_1act) or MKK6_1O_1O_1act) or PKC_beta_1act_plasma_membrane) or PKC_theta_1act_plasma_membrane) or RAC1_CDC42_GTP_1act) or RAC1_GTP_1act_v1) or RET51_GFRalpha1_GDNF_DOK_RasGAP_NCK) or RHOA_GTP_1act) or S1P_S1P2_Gi) or Tie2_Ang1_1act) or p130Cas_CRK_Src_PYK2_1act) grey _h_2649 blue ATF2_2O_nucleus blue _h_4349 TAp63a__tetramer__1act_nucleus_v3 blue _h_2643 E_cadherin_Ca2__beta_catenin_alpha_catenin_p120_catenin_cell_cell_junction_v1 blue _h_5899_31 ErbB2_ErbB3_neuregulin_1_beta_1act_integral_to_membrane_v1 blue _h_2640 (( not Calcineurin_A_alpha_beta_B1) and (IL12_IL12R_TYK2_JAK2_1act_integral_to_membrane or TCR_CD3_MHC_II_CD4_1act_integral_to_membrane)) grey blue _h_2646 GRK2 or GRK6 blue _h_2645 SGK1_1O_1O_1act grey _h_1596 blue ADAM8 grey red _h_1592 blue ErbB4_CYT2_integral_to_membrane _h_1590 blue alphaL_beta2_Integrin_integral_to_membrane blue _h_1591 Cyclin_B1_CDK1_1act_v1 or INCENP grey _h_408 blue beta_Arrestin2_1O_1O grey _h_1599 blue Caspase_6_1act red _h_409 blue MYD88_TIRAP_cytoplasm grey _h_4180 blue RAC1_GTP_1act_cell_cell_junction and filamentous_actin grey blue _h_1437 ((B7_family_CD28_1act_integral_to_membrane_v2 or STAT4__dimer__1act_nucleus_v2) or T_bet) blue _h_2402 HIF2A_ARNT_nucleus_v3 _h_3357 blue TGFB_TGFBR2_TGFBR1_1act_integral_to_membrane red _h_781_2 blue ((MAML1_nucleus and SHARP_RBPJ_nucleus) and p300_nucleus) grey red red red red _h_1219_2 blue 9cRA and RXRs_RARs_RXR_alpha_RAR_alpha and SMRT__N_CoR2_ and (Akt1_1O_1act_1O_1O_plasma_membrane or Erk2_1O_1O_1act) grey grey grey grey red grey grey grey red red blue _h_4186 (AR_T_DHT_nucleus and ( not UBA3)) red blue _h_415 ATF2_2O_1act_nucleus red red grey grey _h_2913 blue NuRD_Complex_nucleus _h_2912 blue JIP4 and not ARF6_GTP_ARF6_GTP_JIP4_Dynactin_Complex_1act _h_2911 blue IL2R_gamma_JAK3_integral_to_membrane and not (SOCS1 or SOCS5) blue _h_2910 not CK2A1_nucleus red grey grey grey _h_2919 blue ((GTP_v1 and LHGCR_1act_integral_to_membrane) and beta_Arrestin2_plasma_membrane) _h_2918 blue CASK grey blue _h_3373_1 DNM1_GTP_1act or RAB5_GTP_1act_v1 blue _h_3373_2 DNM1_GTP_1act or RAB5_GTP_1act_v1 blue _h_4775 JNK2_1O_1O_1act or Jnk1_1O_1act_1O red grey grey blue _h_4771 Src_1O _h_4770 blue E2_ERA__dimer__1act_nucleus _h_4773 blue ILK and beta_catenin grey red blue _h_4779 JUN_FOS_CRTC1_1act_nucleus red red grey grey grey grey red grey red grey grey red grey red blue _h_1473_1 sTNF_alpha_TNFR1A_TRADD_TRAF2_1act_endosome grey grey red grey grey _h_416 blue HGF_dimer__MET_dimer__GAB1_1act_integral_to_membrane_v4 blue _h_4618 ATM blue _h_4619 TCF4_beta_catenin_TNIK_1act_nucleus grey grey blue _h_4612 Fra1_JUN_1act_nucleus _h_4613 blue PDGF_BB_PDGFRB__dimer__1act_integral_to_membrane_v1 blue _h_4610 MDM2_UBCH5_YY1_nucleus grey blue _h_4616 (TAp63g__tetramer__1act_nucleus_v2 and ( not dNp63a__tetramer__1act_nucleus)) red _h_4614 blue FOXO3A_5N_nucleus blue _h_4615 (STAT1__dimer__Cbp_p300_1act_nucleus_STAT1_1O_1O_CBP_nucleus or STAT1__dimer__Cbp_p300_1act_nucleus_STAT1_1O_1O_p300_nucleus) red red grey blue _h_6503 TAp73a__tetramer__nucleus_v3 grey grey grey grey _h_5391 blue betacellulin_extracellular_region grey blue _h_225 Src_1O_1act_cell_cell_junction grey blue _h_756 B7_family_CD28_1act_integral_to_membrane_v2 or TCR_CD3_MHC_II_CD4_LCK_1act_integral_to_membrane red red _h_207 blue alphaE_beta7_Integrin_integral_to_membrane grey _h_753 blue YWHAZ _h_750 blue VAV1_1act_3O_plasma_membrane blue _h_751 PTP1B_plasma_membrane red red blue _h_5146 ILK grey _h_208 blue Dynamin_2_cytoplasm grey blue _h_758 PRL_1 or PRL_3 _h_759 blue CD47 _h_2759 blue Klotho _h_201_3 blue YWHAB grey grey red blue _h_4993_1 Akt1_1O_1act_plasma_membrane_v2 blue _h_2944_49 not E_cadherin_cytoplasm and (MAPK_14 or p120ctn) blue _h_3204 NFAT1_1O_4O_2s_1act_nucleus _h_3205 blue (RALA_GDP_1ina and RALGDS_1act_plasma_membrane) blue _h_3206 PLK1_1O_1act grey red _h_3203 blue alpha1_beta1_Integrin_integral_to_membrane grey blue _h_3208 not ILK_PINCH1_alpha_parvin and (GRB2_SOS1_GAB_family_SHP2_PI3K_1act or ILK_PINCH1 or ILK_RICTOR) grey grey grey _h_5693 blue NPC_RanGAP1_SUMO1_RanBP2_Ubc9 blue _h_5692 (BMP6_BMPR2_BMPR1A_1B_1act or PPM1A) blue _h_5694 PRKACA blue _h_5697 dNp63a__tetramer__nucleus_v2 blue _h_5696 dNp63a__tetramer__nucleus_v2 red blue _h_5698 Akt1_1O_1act_plasma_membrane_v2 blue _h_3118 ARD1 red red grey grey red red grey _h_3349 blue VEGFD__dimer__extracellular_region grey grey _h_6019_1 blue MNK1 _h_3343 blue CaM_Ca2_ _h_3342 blue MET and not E_cadherin_Ca2__beta_catenin_alpha_catenin_p120_catenin_cell_cell_junction_v1 red red _h_3347 blue ((GTP_v1 and ( not (Ca2__v1 or Galectin3))) and (((CalDAG_GEF1_1act_plasma_membrane or DAG_v2) or GRB2_SOS1_plasma_membrane) or RASGRP4_1act)) blue _h_3346 PTP1B red _h_5969 blue B_cell_antigen_BCR_complex grey grey blue _h_5963 Vitronectin or alphav_beta3_Integrin grey blue _h_5961 EGR1_nucleus grey blue _h_5967 MYC_Max_nucleus_v2 blue _h_5966 MYC_Max_nucleus_v2 red grey red grey red _h_3654_8 blue Src_family_SYK_family_BLNK_LAT_1act_SYK_Family_Kinases_active_1act_LAT_10O_1act_Src_1act_1O grey red grey red _h_3654_2 blue ITK_plasma_membrane _h_3654_3 blue Src_family_SYK_family_BLNK_LAT_1act_SYK_Family_Kinases_active_1act_LAT_10O_1act_LYN_1act_1O _h_3654_4 blue Src_family_SYK_family_BLNK_LAT_1act_SYK_Family_Kinases_active_1act_LAT_10O_1act_Src_1act_1O _h_3654_5 blue Btk_plasma_membrane _h_3654_6 blue Src_family_SYK_family_BLNK_LAT_1act_SYK_Family_Kinases_active_1act_LAT_10O_1act_Fyn_1O_1act red red grey blue _h_4580_1 (((GNA14_GTP_1act or GNA15_GTP_1act) or GNB1_GNG2_1act) or Gq_family_GTP_1act) blue _h_5411 Lethal_Factor_cytoplasm blue _h_4580_2 GNA14_GTP_1act or GNA15_GTP_1act or GNB1_GNG2_1act or Gq_family_GTP_1act _h_2751_3 blue 14_3_3_E _h_2751_2 blue SIK3_1O_1act_cytoplasm grey blue _h_4149 TAp63g__tetramer__1act_nucleus_v2 red red _h_2751_4 blue SIK3_1O_1act_cytoplasm red blue _h_4146 LEF1_beta_catenin_1act_nucleus_v1 red grey red red _h_4147 blue Fra2_1O_1O_nucleus grey red _h_159 blue CHD3_nucleus and CHD4_nucleus and HDAC_complex_nucleus_v1 and MTA2_nucleus and p66_alpha_nucleus and p66_beta_nucleus grey grey grey grey red grey red red grey grey grey red grey grey blue _h_2347 TAp63a__tetramer__1act_nucleus_v3 _h_2344 blue SMAD5_cytoplasm grey blue _h_2342 PAK1_1act_cytoplasm _h_2343 blue Fibrinogen_extracellular_region blue _h_2340 LKB1_MO25_STRADA_STRADB_cytoplasm_v2 blue _h_5051_2 (RAS_family_GTP_1act_plasma_membrane_H_RAS_isoform_1_GTP_v1 or RAS_family_GTP_1act_plasma_membrane_N_RAS_GTP_v1) _h_354 blue Src red _h_2348 blue ER_alpha_nucleus and HDAC1_nucleus and LMO4 grey grey grey red blue _h_1524 Arf6_GTP_1act grey red _h_571 blue p52_SHC and (BDNF__dimer__TRKB_1act_endosome_v2 or NGF__dimer__TRKA_1act_endosome or NT3__dimer__TRKC_1act_endosome or NT_4_5__dimer__TRKB_1act_endosome) _h_1251 blue E_cadherin_beta_catenin_gamma_catenin_alpha_catenin_p120_catenin_integral_to_membrane red red red _h_1250 blue BoNT_D_Light_Chain_1act_cytoplasm or BoNT_F_Light_Chain_1act_cytoplasm grey blue _h_3836 DMN1_GTP_1act or EPS15_plasma_membrane blue _h_3835 AR_RACK1_Src_nucleus grey blue _h_3832 HIF1A_ARNT_nucleus grey _h_3830 blue MEKK3 grey grey grey red blue _h_1622 MYC_Max_nucleus_v2 blue _h_3839 TAp63b__tetramer__1act_nucleus_v2 blue _h_3838 ELK1_SRF_1act_nucleus_v2 red blue _h_1991 eIF4B_1O_translation_preinitiation_complex _h_6326 blue alphaD_beta2_Integrin_integral_to_membrane red red red blue _h_2122 mTORC1_1act or p70S6K_3O_4O blue _h_2123 (GATA3_nucleus or RBPJ_NICD_1act_nucleus) _h_2120 blue Nephrin_NEPH1_integral_to_membrane and not Fyn_1O_1act blue _h_2121 CDC42_GTP_1act_plasma_membrane blue _h_2126 not MYC_Max_nucleus_v4 grey blue _h_2124 GNA11_1act or GNA14_1act or GNA15_1act or GNAQ_1act or HGF_dimer__MET_dimer__GAB1_1act_integral_to_membrane_v4 or S1P1_S1P_Gi_1act_GNAI1_1act_S1P1_1act_S1P_extracellular_region or S1P1_S1P_Gi_1act_GNAI2_1act_S1P1_1act_S1P_extracellular_region or S1P1_S1P_Gi_1act_GNAI3_1act_S1P1_1act_S1P_extracellular_region or S1P1_S1P_Gi_1act_GNAO1_1act_S1P1_1act_S1P_extracellular_region or S1P1_S1P_Gi_1act_GNAZ_1act_S1P1_1act_S1P_extracellular_region or S1P_S1P4_Gi or VEGFR1_homodimer_PLGF_homodimer_1act_plasma_membrane grey grey blue _h_2128 ((GATA3 or JUN_FOS_NFAT1_c_4_1act_nucleus) and ( not (HDAC1_nucleus or cortisol_GR_alpha__monomer__nucleus))) red red blue _h_5383 TAp73a__tetramer__nucleus_v3 and not dNp73a__tetramer__nucleus_v2 grey red blue _h_4194_1 PI_3_4_P2_plasma_membrane blue _h_5051_22 (RAS_family_GTP_1act_plasma_membrane_H_RAS_isoform_1_GTP_v1 or RAS_family_GTP_1act_plasma_membrane_N_RAS_GTP_v1) red grey blue _h_6208 not cortisol_GR_alpha__dimer__nucleus_v3 and (CBP or cortisol_GR_alpha_BRG1_BAF155_BAF170_BAF60A_nucleus or p300) grey _h_186_3 blue KLHL12_Cul3 _h_3263_18 blue FGFR1c_FGF2_1act _h_3263_19 blue FGFR1b_FGF1_1act blue _h_4188 dNp63a__tetramer__nucleus_v2 red blue _h_6454 (( not E2F7) and ((E2F1_3_DP_nucleus_DP1_E2F1 or E2F1_3_DP_nucleus_DP1_E2F2) or E2F1_3_DP_nucleus_DP1_E2F3)) grey _h_3263_10 blue FGFR1c_FGF5_1act grey _h_3263_12 blue FGFR1c_FGF5_1act _h_3263_13 blue FGFR1c_FGF2_1act _h_3263_14 blue FGFR1c_FGF2_1act blue _h_4187 STAT6__dimer__1act_nucleus_v1 red grey red red red red blue _h_5051_23 (RAS_family_GTP_1act_plasma_membrane_H_RAS_isoform_1_GTP_v1 or RAS_family_GTP_1act_plasma_membrane_N_RAS_GTP_v1) _h_6032 blue alphaM_beta2_Integrin_integral_to_membrane blue _h_6446 FOXM1B_HNF6_nucleus red grey grey red red grey grey blue _h_2811 Myb_nucleus red _h_1695 blue PLC_beta3_1act_plasma_membrane or PLC_beta_1_1act_plasma_membrane or PLC_beta_2_1act_plasma_membrane red _h_1697 blue TCF1_TLE2_1act_nucleus blue _h_1696 dNp63g__tetramer__nucleus blue _h_1691 TAp73b__tetramer__nucleus blue _h_1690 NF_kappa_B_RelA_I_kappa_B_alpha_ubiquitin grey grey blue _h_1699 E_cadherin_Ca2__beta_catenin_gamma_catenin_alpha_catenin_p120_catenin_cell_cell_junction_v2 grey grey red grey red blue _h_3384 ETB_receptor_Endothelin_1_integral_to_membrane _h_4660_1 blue FGFR_FGF_v2 _h_4660_2 blue FGFR4_FGF19 grey grey grey grey grey red _h_4076_4 blue (FOXO4_14_3_3_family_nucleus_YWHAB_FOXO4_1O_2O and Ran_GTP_Exportin_1) blue _h_5361 FOXM1B_HNF6_nucleus red grey grey _h_5365 blue JAM_A _h_5367 blue GTP_v1 and VEGFR2__dimer__VEGFA__dimer__1act_integral_to_membrane_v2 blue _h_5366 PLCgamma1_3O_1act_cytoplasm _h_5369 blue GATA1_p300_1act_nucleus grey red blue _h_6311 not MYC_Max_nucleus_v4 grey grey blue _h_6312 RAP1_GTP_1act_cell_cell_junction _h_6315 blue alpha4_beta1_Integrin_integral_to_membrane_v1 _h_6314 blue PDGFA_B_C_extracellular_region _h_6317 blue LRPAP1 blue _h_1476 (((((((((IL2_IL2R_alpha_beta_gamma_JAK1_LCK_JAK3_SHC_GAB2_GRB2_SOS1_SHP2_PI3K_1act_integral_to_membrane or PI3K_1act_plasma_membrane_v2) or PI3K_beta_1act_plasma_membrane) or PI3K_delta_1act_plasma_membrane) or PI3K_p110_alpha_p55_gamma_1act_plasma_membrane) or PI3K_p110_alpha_p85_beta_1act_plasma_membrane) or PI3K_p110_beta_p55_gamma_1act_plasma_membrane) or PI3K_p110_beta_p85_beta_1act_plasma_membrane) or PI3K_p110_delta_p55_gamma_1act_plasma_membrane) or PI3K_p110_delta_p85_beta_1act_plasma_membrane) blue _h_6319 PCAF_nucleus blue _h_1478 EPS15b_1act_endosome grey grey grey grey _h_2710 blue TRAP_1_SMAD4 _h_1424 blue MEK2_cytoplasm and RAF1_1O_1act_v2 blue _h_1506 SIK1_1O_1act_cytoplasm grey grey red red red grey red red grey blue _h_807_20 FASLG_FAS__trimer__Src_Syk_1act_integral_to_membrane or TRAIL__trimer__extracellular_region grey red _h_3381 blue DCC_integral_to_membrane and UNC5B_integral_to_membrane grey grey blue _h_2716 HIF2A_ARNT_nucleus_v3 blue _h_5051_28 (RAS_family_GTP_1act_plasma_membrane_H_RAS_isoform_1_GTP_v1 or RAS_family_GTP_1act_plasma_membrane_N_RAS_GTP_v1) _h_5903 blue NRP2 and VEGFR2_integral_to_membrane red grey red red grey _h_4269 blue FOXM1C_2O_1act_nucleus grey grey _h_4268 blue Aurora_A and NDEL1 grey grey grey red grey red _h_5750 blue HMGB1_integral_to_membrane and TLR1_integral_to_membrane grey red blue _h_5753 (mTOR_1O_1act and ( not cAMP)) blue _h_5754 SMAD3_SMAD4_IRF7_1act_nucleus _h_5755 blue SMURF2 blue _h_5756 HIF2A_ARNT_SIRT1_nucleus _h_5908 blue RIP and TRADD red _h_5759 blue HEY1_nucleus grey red grey red grey _h_3481 blue CD40_CD40L__trimer__integral_to_membrane grey red red _h_4325 blue HGF_dimer__MET_dimer__1act_integral_to_membrane_v3 _h_1112 blue AR_T_DHT_nucleus and TIF2 _h_2642_1 blue FAK_Src_Yes_Fyn_1act_focal_adhesion_v2_Src_1act_1O_FAK_6O_1act red grey grey _h_118_6 blue YWHAG and chibby _h_118_5 blue 14_3_3_E and beta_catenin_nucleus _h_118_4 blue beta_catenin_nucleus and chibby red _h_118_2 blue YWHAB and chibby _h_118_1 blue YWHAZ and beta_catenin_nucleus blue _h_5575 not (CDC42_GTP_IQGAP1_cell_cell_junction or RAC1_GTP_IQGAP1_cell_cell_junction) blue _h_433 PIAS3 _h_924 blue SDF1_CXCR4_1act_integral_to_membrane blue _h_431 SPHK1_1act_plasma_membrane or SPPase1 _h_926 blue HDAC4_nucleus blue _h_437 (( not STAT1__dimer__1act_v1) and (IL6_extracellular_region or TGFB1_extracellular_region)) blue _h_436 ( not IFN_gamma_IRF1) blue _h_923 ((E2_ER_beta__dimer__1act_plasma_membrane or MKK3_1O_1O_1act) or MKK6_1O_1O_1act) grey red grey blue _h_766_1 ((BRAF_1O_1act_cytoplasm or IL2_IL2R_alpha_beta_gamma_JAK1_LCK_JAK3_SHC_GAB2_GRB2_SOS1_SHP2_PI3K_1act_integral_to_membrane) or RAF1_1O_1O_1act_cytoplasm) grey grey grey red grey grey blue _h_695 TCR_CD3_MHC_II_CD4_LCK_ZAP_70_1act_integral_to_membrane blue _h_2944_36 not E_cadherin_cytoplasm and (MAPK_14 or p120ctn) grey _h_692 blue IL4_IL4R_JAK1_IL2R_gamma_JAK3_1act_integral_to_membrane and STAT6__dimer__1act_nucleus_v1 grey blue _h_690 (IL12_IL12R_TYK2_JAK2_1act_integral_to_membrane or SDF1_CXCR4_1act_integral_to_membrane) blue _h_2944_39 not E_cadherin_cytoplasm and (MAPK_14 or p120ctn) grey grey _h_698 blue E2_ER_alpha__dimer__PELP1_Src_1act_caveola_v2 grey red red grey red grey grey grey grey _h_3635 blue HSP60_TLR4_MD2__dimer__1act_integral_to_membrane blue _h_1043_1 not SLAP and (CSK_1act_plasma_membrane or PDGF_BB_PDGFRB__dimer__1act_integral_to_membrane_v1) grey _h_1012 blue Nephrin_NEPH1_cell_cell_junction grey _h_1199 blue HGF_dimer__MET_dimer__1act_integral_to_membrane_v1 and not MET_MUC20_1ina grey _h_4409 blue GRB2_GAB2 blue _h_4408 JUN_FOS_1act_nucleus_v1 and not cortisol_GR_alpha__monomer__nucleus _h_4407 blue Laminin_1_basement_membrane _h_4406 blue IL2R_gamma_JAK3_integral_to_membrane and IL2_1O_extracellular_region blue _h_4405 Erk2_1O_1O_1act red red _h_4402 blue Su_fu__nucleus _h_4401 blue IL3_IL3RA_CSF2RB__dodecamer__YWHAZ_1act_integral_to_membrane grey red blue _h_1192 CK2 red red grey grey grey blue _h_533 Erk2_1O_1O_1act grey grey red grey red _h_187 blue ErbB2_ErbB3_neuregulin_1_beta_SHC_1act_integral_to_membrane and not SHP2_1O_1act_neuromuscular_junction grey red red grey red red red grey red red grey _h_3263_39 blue FGFR1c_FGF1_1act red red grey blue _h_4832 TIP60 or hMOF grey grey red grey red grey grey grey grey grey grey red grey red grey _h_921_3 blue KSR_1act_plasma_membrane or RAS_family_GTP_1act_plasma_membrane_H_RAS_isoform_1_GTP_v1 or RAS_family_GTP_1act_plasma_membrane_N_RAS_GTP_v1 grey _h_921_1 blue KSR_1act_plasma_membrane or RAS_family_GTP_1act_plasma_membrane_H_RAS_isoform_1_GTP_v1 or RAS_family_GTP_1act_plasma_membrane_N_RAS_GTP_v1 grey _h_921_6 blue KSR_1act_plasma_membrane or RAS_family_GTP_1act_plasma_membrane_H_RAS_isoform_1_GTP_v1 or RAS_family_GTP_1act_plasma_membrane_N_RAS_GTP_v1 red _h_921_4 blue KSR_1act_plasma_membrane or RAS_family_GTP_1act_plasma_membrane_H_RAS_isoform_1_GTP_v1 or RAS_family_GTP_1act_plasma_membrane_N_RAS_GTP_v1 _h_228_2 blue ETA_receptor_Endothelin_1_Gq_GTP_1act_integral_to_membrane grey grey red _h_2821_2 blue SMAD2_3_SMAD4_FOXO1_3a_4_1act_nucleus_v2_FOXO1_3a_4_1act_Smad3_2O_1act_SMAD4 red blue _h_5116 ((JUN_FOSNFAT1_c_4_1act_nucleus_c_Jun_2O_NFAT1_1O_7O_2s_1act_nucleus_FOS_1O_1O or JUN_FOSNFAT1_c_4_1act_nucleus_c_Jun_2O_NFAT4_1act_nucleus_FOS_1O_1O) or JUN_FOSNFAT1_c_4_1act_nucleus_c_Jun_2O_NFATc_1act_nucleus_FOS_1O_1O) red _h_5114 blue Syndecan_3 grey blue _h_5112 PKC_1act blue _h_5113 (((IL2_IL2R_alpha_beta_gamma_JAK1_LCK_JAK3_SHC_GAB2_GRB2_SOS1_SHP2_PI3K_1act_integral_to_membrane or STAT5A_B__dimer__1act_nucleus) or STAT5A__dimer__active_1act_nucleus_v2) or STAT5B__dimer__1act_nucleus) grey red blue _h_6384 NF_kappa_B1_RelA_1act_nucleus red grey grey grey grey _h_6126 blue A20 and NEMO_cytoplasm grey red grey _h_6123 blue TCF3_TLE2_1act_nucleus blue _h_6120 (PAX3_nucleus and ( not RB1_nucleus)) blue _h_6121 (STAT4__dimer__JUN_1act_nucleus or T_bet) _h_1966 blue NPC_RanGAP1_SUMO1_Ubc9 and SUMO1_cytoplasm grey grey grey _h_5844 blue eNOS_plasma_membrane grey red _h_5460_5 blue LPA_LPA1 red grey grey red grey red grey red grey blue _h_3628 ATF2_CREB1_1act_nucleus grey grey _h_969_1 blue SMAD2_3_SMAD4_SP1_1act_nucleus_SP1_Smad3_2O_1act_SMAD4 red red blue _h_4837 MYC_Max_nucleus_v2 blue _h_1893 JUN_ATF2_1act_nucleus grey blue _h_3629 Fra2_JUN_1act_nucleus_v2 red grey _h_6222 blue (((BMP7__dimer__extracellular_region and BMPR1A_1B__homodimer__integral_to_membrane) and BMPR2__homodimer__1act_integral_to_membrane) and USAG1) grey grey grey grey red grey red _h_1963 blue Gelsolin blue _h_6442 TAp63g__tetramer__1act_nucleus_v2 _h_1549 blue PAR1_active_1act_integral_to_membrane red grey red red grey red grey grey grey red red grey red blue _h_1548 PP2A_1act_v2 grey grey red grey grey blue _h_539 JUN_JUNB_1act_nucleus grey _h_2664 blue MRN_complex_ATM_MDC1_H2AX_1act_site_of_double_strand_break and UBC13 red blue _h_2666 WNT3A_LRP6_FZD5_DVL_1act_integral_to_membrane_v2 blue _h_2661 dNp63g__tetramer__nucleus _h_4105_1 blue (FOS_3O_1O_1act_nucleus and JUN_2O_1act_nucleus) blue _h_2662 EGFR_EGFR_EGF_EGF_integral_to_membrane_v1 and not GRB2 blue _h_345 TAp63a__tetramer__1act_nucleus_v3 blue _h_2669 TCR_CD3_MHC_II_CD4_LCK_1act_integral_to_membrane or TCR_CD3_MHC_I_CD8_LCK_1act_integral_to_membrane blue _h_2668 Insulin_Receptor_Insulin_v2 blue _h_1314 ( not MYC_Max_HDAC3_nucleus) blue _h_1315 PKC_zeta_Par3_Par6_CDC42_GTP _h_1316 blue PTP1B_plasma_membrane _h_1317 blue N_cadherin_p120_catenin_beta_catenin_alpha_catenin_integral_to_membrane blue _h_2939 not Myb_MAF_nucleus and (ETS1_nucleus or Myb_nucleus) _h_1311 blue PKC_isoenzymes _h_1828_1 blue NOTCH2_heterodimer_integral_to_membrane blue _h_2937 ( not MYC_Max_nucleus_v4) _h_346 blue MED12_nucleus grey grey blue _h_2933 CEBPB or STAT3__dimer___1act_nucleus _h_1056 blue (VCAM1_integral_to_membrane and alpha4_beta1_Integrin_integral_to_membrane_v1) grey _h_4798 blue Src_plasma_membrane _h_4796 blue Laminin_5_basement_membrane grey blue _h_4794 (JUN_ATF2_1act_nucleus and ( not JUN_FOS_1act_nucleus_v1)) blue _h_4793 Myb_nucleus blue _h_4792 IL23_IL23R_JAK2_TYK2_1act_integral_to_membrane blue _h_4791 FOXM1B_nucleus _h_4790 blue BoNT_A_Light_Chain_1act_cytoplasm or BoNT_C1_Light_Chain_1act_cytoplasm grey red grey grey red red grey grey grey blue _h_4683_2 GNAI1_1act or GNAI2_1act or GNAI3_1act or GNAO1_1act or GNAZ_1act _h_594 blue HPK1 and TCR_CD3_MHC_II_CD4_LCK_ZAP_70_1act_integral_to_membrane _h_595 blue PLCgamma2_1O blue _h_596 TAp63a__tetramer__1act_nucleus_v3 grey blue _h_590 (RanBP3 or TGFB_TGFBR2_TGFBR1_STRAP_SMAD7_1act_integral_to_membrane) _h_591 blue FANCJ grey _h_593 blue MYD88_TIRAP_cytoplasm red grey grey red red grey grey grey grey red grey red grey grey red blue _h_5332_1 MKP3_1act grey grey grey red blue _h_771 beta_catenin_PITX2_1act grey _h_774 blue E2F1_DP_nucleus_v4 grey blue _h_777 TAp63g__tetramer__1act_nucleus_v2 blue _h_778 26S_Proteasome or UCHL1_v2 _h_779 blue G12_G13_cytoplasm and S1P4 grey grey grey grey grey grey _h_4354 blue RAC1_GDP and RAC1_GTP grey grey grey red grey blue _h_4077 pro_uPA_alphaM_beta2_Integrin_1act_integral_to_membrane or uPA_uPAR_1act_plasma_membrane_v1 red grey blue _h_3228 LIMK1_fragment_1O_1act red blue _h_3226 Fra1_JUND_1act_nucleus blue _h_3227 ((STAT5A_B__dimer__1act_nucleus or STAT5A__dimer__active_1act_nucleus_v2) or STAT5B__dimer__1act_nucleus) grey _h_3225 blue CK1_alpha and (Ca2__cytoplasm or MEKK1_2O_1act) grey _h_3220 blue SMAD3_SMAD4_1act_nucleus blue _h_3221 ceramide red grey blue _h_1154_2 CD40_CD40L__trimer__TRAF3__trimer__integral_to_membrane grey grey blue _h_4898 not Myb_nucleus and (ETS1_nucleus or ETS2_nucleus or SPI1_nucleus) blue _h_6497 p38_alpha_1O_1O_1act_v2 or p38_beta_1O_1O_1act grey red grey _h_6491 blue DNM1 and TXA2_TP_beta_1ina_integral_to_membrane and not (Gq_family_GTP_EBP50_1ina or RAC1_GTP_1act_v1) _h_4890 blue PDGF_BB_PDGFRB__dimer__1act_integral_to_membrane_v1 red blue _h_4892 TAp73b__tetramer__nucleus red blue _h_4894 NFAT1_1O_4O_2s_1act_nucleus blue _h_4895 TXA2_TXA2_R_family_1act_integral_to_membrane red blue _h_4897 ATM or ATM_3O_1N_site_of_double_strand_break or WIP1 red _h_3322 blue FKBP25_nucleus and HDAC1_nucleus grey grey red _h_3325 blue PKC_zeta and p62 _h_3324 blue NRP2 and VEGFR2_integral_to_membrane and VEGFR3_integral_to_membrane grey blue _h_5945 MYC_Max_nucleus_v2 blue _h_5944 Ephrin_A1_EPHA2_LMW_PTP_1act_integral_to_membrane or SHP2 blue _h_5947 ASK1_1act or FAS_FADD_DAXX_Ask1_Caspase_8_Caspase_8_FASLG or MEKK1_2O_1act or TNFR1A_Caspase_2_TNF_alpha_FADD_TRADD_RIP_cIAP2_TRAF1_TRAF2_Ask1_RAIDD _h_5946 blue RAP1A_GTP_1act grey _h_3186 blue SARA_plasma_membrane and TGFB_TGFBR2_TGFBR1_SMAD7_GADD34_1act_integral_to_membrane red grey _h_5948 blue GTP_v1 and PKC_alpha_1act blue _h_164 CDC42_GTP_ACK1 grey blue _h_3184 APAF_1_Caspase_9_1act or Caspase_8__4_units__1act _h_3749 blue Gi_family and S1P_extracellular_region grey _h_166 blue FZD2_integral_to_membrane red grey grey grey red _h_5682 blue EGFR_integral_to_membrane and ErbB2_integral_to_membrane grey red red red grey grey grey _h_2367 blue ARF1_GTP_1act and Arfaptin_2_RAC1_GDP red red grey _h_6447_3 blue CEBPB_nucleus _h_2361 blue Nephrin_NEPH1_podocin_membrane_raft_v1 grey _h_2362 blue NEDD4_2 grey grey grey blue _h_4300 SCF_KIT_1act grey red red blue _h_6404 RCH1__importin_beta and not NRON_rna _h_6447_2 blue CEBPA_nucleus grey red red blue _h_1328 CEBPB_PTGES2_Cbp_p300_1act_nucleus_PTGES2_CEBPB_1O_v2_CBP_nucleus or CEBPB_PTGES2_Cbp_p300_1act_nucleus_PTGES2_CEBPB_1O_v2_p300_nucleus _h_2587 blue NCK2 grey blue _h_4088 Jak2_1act_1O grey red red blue _h_2320 FOXA1_nucleus or FOXA2_nucleus_v2 red _h_2322 blue RelB_1O_cytoplasm grey blue _h_2324 AP1_1act_nucleus blue _h_2325 TCRz_NEF red grey blue _h_2329 JNK2_1O_1O_1act or Jnk1_1O_1act_1O red blue _h_4574_4 EHD4_1act blue _h_4574_5 EHD4_1act blue _h_4574_6 EHD4_1act red grey grey grey blue _h_4574_3 EHD4_1act grey red blue _h_4574_8 EHD4_1act blue _h_4574_9 EHD4_1act blue _h_3811 p53__tetramer__nucleus_v2 _h_3810 blue L_arginine_cytoplasm and O2 and (GAB1_SHP2_PKA_eNOS or GAB1_SHP2_PKA_eNOS_1act or Hsp90B_eNOS_v1 or NOS2_1p_1act or eNOS_1m_1p_1O_1p_1act_caveola or eNOS_2O_1act_cytoplasm or eNOS_Hsp90_plasma_membrane_v2) _h_3812 blue HES1_nucleus _h_3815 blue LAT_GRAP2_SLP76_VAV1_ITK_1act_integral_to_membrane _h_3814 blue IKK_beta_1act or NF_kappa_B_RelA_1act_cytoplasm_v1 _h_3817 blue Tiam1_cytoplasm blue _h_3816 (( not PKC_theta_1act_plasma_membrane) and ((NFAT1_c_4__dimer__EGR1_NFAT1_1O_7O_2s_1act_nucleus_EGR1_nucleus or NFAT1_c_4__dimer__EGR1_NFAT4_1act_nucleus_EGR1_nucleus) or NFAT1_c_4__dimer__EGR1_NFATc_1act_nucleus_EGR1_nucleus)) red blue _h_3818 Myb_nucleus _h_3744 blue PIAS1_nucleus grey red grey grey _h_5742 blue alpha6_beta4_Integrin_Laminin_hemidesmosome grey grey grey grey blue _h_4303 FOXO4_nucleus blue _h_4953 SMAD4_SMAD1_5_8__dimer__1act_nucleus grey _h_2499 blue Dok6 and Src_1O_1act_plasma_membrane red red _h_2492 blue Syndecan_2 _h_2491 blue PKACB blue _h_2496 (Erk1_1O_1act_1O_cytoplasm or Erk2_1O_1O_1act_cytoplasm) red blue _h_2494 LPA_LPA2_NHERF2 red grey grey grey blue _h_4002 dNp63a__tetramer__nucleus_v2 red blue _h_4304 not HES1_nucleus grey grey red red grey grey grey blue _h_4000 Crk_1act_cell_leading_edge red grey grey _h_4006 blue VEGFA189__dimer__extracellular_region _h_5127 blue GRB2_SOS1_v1 grey red red grey grey grey red grey grey red grey red _h_1677 blue epiregulin_extracellular_region _h_401_1 blue RB1_E2F1_3_DP_nucleus_v3_DP1_RB1_E2F2 _h_1675 blue GRB2_SOS1_cytoplasm blue _h_1674 E2_ERA__dimer__AIB1_1act_nucleus grey blue _h_1672 Erk2_1O_1O_1act blue _h_1671 not E2F6_DP_nucleus _h_1670 blue ABI1_1act red grey grey grey _h_5015_1 blue PPP2R1A_PPP2CA_PPP2R2A_1act blue _h_1375 ATF2__dimer__1act_nucleus grey grey red grey blue _h_2434_53 ((EGFR_EGFR_1act_integral_to_membrane_v1 or EGFR_EGFR_EGF_EGF_GRB2_GAB1_1act_integral_to_membrane_v1) and ( not (EGFR_EGFR_1ina_integral_to_membrane or EGFR_EGFR_EGF_EGF_GRB2_GAB1_1ina_integral_to_membrane))) blue _h_2885_1 WNT1_FZD7_FZD1_1act_integral_to_membrane or WNT3A_WNT5A_FZD5_FZD6_ROR2_dimer__CTHRC1_trimer__1act_endosome or WNT5A_FZD7_ROR2_dimer__1act_integral_to_membrane red _h_73_1 blue beta_Arrestin1 _h_73_2 blue beta_Arrestin2 _h_5308 blue PLD1_1O_2O_1act_plasma_membrane or PLD1_1act_plasma_membrane or PLD2_1act_plasma_membrane red grey grey blue _h_5301 STAT4__dimer__1act_nucleus_v2 blue _h_5300 Jnk1_1O_1act_1O _h_5307 blue Laminin_5 blue _h_5306 PKC_isoenzymes blue _h_5305 p38_alpha_1O_1O_1act_v2 or p38_beta_1O_1O_1act blue _h_5304 JUN_FOS_1act_nucleus_v4 grey _h_6379 blue Syntenin and not Syndecan_4_1O_v1 grey grey red _h_6373 blue TRKC_1N_integral_to_membrane _h_1412 blue Fyn_1O_1act _h_6371 blue EGFR_integral_to_membrane and ErbB3 blue _h_1410 LKB1_MO25_STRADA_STRADB_cytoplasm_v1 blue _h_1417 (( not E2F6_DP_nucleus) and (E2F1_DP_nucleus_v4 or SP1)) _h_6376 blue LYN red _h_6374 blue SHIP_cytoplasm grey red red red blue _h_6112 c_Abl_1act_1O _h_4309 blue CBP_cytoplasm grey grey red _h_1722 blue IP6 _h_1895 blue VEGFR2__dimer__VEGFA__dimer__1act_integral_to_membrane_v1 _h_2928 blue C3G_1O blue _h_2349 BUB1 or CENP_A_1O_1act or RKIP_1O red grey _h_2075_2 blue FOXO3A_1O_2O_nucleus and YWHAB_nucleus _h_2075_3 blue FOXO3A_1O_2O_nucleus and YWHAG_nucleus grey grey _h_2075_6 blue FOXO3A_1O_2O_nucleus and YWHAQ_nucleus _h_2075_4 blue FOXO3A_1O_1O_nucleus and FOXO3A_1O_2O_nucleus _h_2075_5 blue FOXO3A_1O_1O_nucleus and FOXO3A_1O_2O_nucleus grey grey red blue _h_1890 JNK2_1O_1O_1act or Jnk1_1O_1act_1O grey grey _h_236 blue ARF1_GTP_1act_peroxisome and ATP grey _h_2215 blue LPA4_plasma_membrane red grey blue _h_5840 FOXA2_nucleus_v1 blue _h_2063 ATM_1act or ATR_1act red _h_3987 blue SHC_GRB2_SOS1_1act_integral_to_membrane and (BDNF__dimer__TRKB_1act_endosome_v2 or NGF__dimer__TRKA_1act_endosome or NT3__dimer__TRKC_1act_endosome or NT_4_5__dimer__TRKB_1act_endosome) red grey grey grey blue _h_5772 beta_TrCP1_1act_v2 _h_5773 blue VEGFR3_VEGFD_1act_plasma_membrane grey grey blue _h_5776 HIF1A_ARNT_nucleus blue _h_5777 NF_Kappa_B1_1act red grey _h_907 blue ((((((MMP12_1act or Plasmin_1act) or cathepsin_G_1act_extracellular_region) or chymotrypsin_C_1act) or kallikrein_4_1act) or neutrophil_elastase_1act) or uPA_1act_extracellular_region_v1) blue _h_906 MEK1_2O_1act_cytoplasm blue _h_905 Akt1_1O_1act_1O_1O_plasma_membrane grey blue _h_903 CK2A1 _h_902 blue CDC6_3O_1act grey grey grey blue _h_1036_134 Arf6_GTP_1act or Arf6_GTP_1act_plasma_membrane blue _h_909 TERT grey grey blue _h_3981 Arf6_GTP_1act_plasma_membrane or PI_3_4_5_P3_plasma_membrane blue _h_1036_70 Arf6_GTP_1act or Arf6_GTP_1act_plasma_membrane _h_4721 blue Gab1_1act_1O and PIK3R1 and SHC_cytoplasm and SHP2 blue _h_1036_132 Arf6_GTP_1act or Arf6_GTP_1act_plasma_membrane blue _h_2107 CDK1 grey grey grey blue _h_1036_133 Arf6_GTP_1act or Arf6_GTP_1act_plasma_membrane _h_3991_1 blue p190RhoGAP grey grey grey grey red red _h_3284 blue BARD1 _h_4260 blue GTP_v1 and (FAK_Src_Yes_Fyn_GRB2_SOS1_1act_focal_adhesion_GRB2_Fyn_1O_1act_SOS1_1act_FAK_6O_1act or FAK_Src_Yes_Fyn_GRB2_SOS1_1act_focal_adhesion_Src_1act_1O_GRB2_SOS1_1act_FAK_6O_1act) blue _h_2944_19 not E_cadherin_cytoplasm and (MAPK_14 or p120ctn) blue _h_2944_18 not E_cadherin_cytoplasm and (MAPK_14 or p120ctn) grey blue _h_2944_16 not E_cadherin_cytoplasm and (MAPK_14 or p120ctn) blue _h_2944_15 not E_cadherin_cytoplasm and (MAPK_14 or p120ctn) blue _h_2944_14 not E_cadherin_cytoplasm and (MAPK_14 or p120ctn) blue _h_2944_13 not E_cadherin_cytoplasm and (MAPK_14 or p120ctn) blue _h_2944_12 not E_cadherin_cytoplasm and (MAPK_14 or p120ctn) blue _h_2944_11 not E_cadherin_cytoplasm and (MAPK_14 or p120ctn) blue _h_2944_10 not E_cadherin_cytoplasm and (MAPK_14 or p120ctn) blue _h_2497 TAp73a__tetramer__nucleus_v3 red grey grey grey blue _h_4267 E2_ERA__dimer__1act_nucleus _h_3282 blue PI_4_5_P2_plasma_membrane and Talin_plasma_membrane _h_5460_1 blue LPA_LPA1 red blue _h_3283 Fra1_JUN_1act_nucleus _h_3429 blue Fibrinogen_extracellular_region red red _h_5618 blue proNGF__dimer__p75_NTR__Sortilin_TRAF6_1act_integral_to_membrane red grey _h_2922 blue alpha6_beta1_Integrin_integral_to_membrane blue _h_2630 ( not dNp63a__tetramer__nucleus_v2) grey blue _h_4911 Arf6_GTP_1act red grey blue _h_2495 FOXM1B_nucleus blue _h_4429 DAG_v2 blue _h_4428 SHH_Np_Cholesterol_PTCH1_integral_to_membrane grey blue _h_4421 TAp63g__tetramer__1act_nucleus_v2 blue _h_4420 TAp73b__tetramer__nucleus grey _h_4425 blue CDC25C_1O red red blue _h_694 TAp73a__tetramer__nucleus_v3 _h_3263_35 blue FGFR1c_FGF5_1act blue _h_6034 IL2_IL2R_1act_integral_to_membrane red blue _h_5610 (SP1_3_nucleus and ( not p53__tetramer__SP1_nucleus)) grey grey grey blue _h_5612 TAp73b__tetramer__nucleus _h_3263_30 blue FGFR1b_FGF2_1act blue _h_5615 LKB1_ER_alpha_nucleus grey grey grey red blue _h_1542 ( not Ephrin_B1_EPHB1_2_1act_integral_to_membrane_v1) _h_5617 blue NuRD_MBD3_Complex_nucleus blue _h_2061 STAT5A_B__dimer__1act_nucleus or STAT5A__dimer__active_1act_nucleus_v2 or STAT5B__dimer__1act_nucleus grey red grey grey _h_455_4 blue RAF1_14_3_3_1act_plasma_membrane_RAF1_1O_3O_YWHAB grey _h_455_2 blue RAF1_14_3_3_1act_plasma_membrane_RAF1_1O_3O_YWHAG _h_455_1 blue BRAF_14_3_3_1act_plasma_membrane_14_3_3_E_BRAF_1O_2O grey grey red _h_530 blue NCoR2 red _h_3026_2 blue EPHB3_integral_to_membrane red grey _h_536 blue PLK1_1O_1act red red red _h_537 blue PLK1_1O_1act_centrosome red red red _h_5460_4 blue LPA_LPA1 grey grey red blue _h_1173_1 IL2_IL2R_alpha_beta_gamma_JAK1_LCK_JAK3_SHC_1act_integral_to_membrane grey red grey blue _h_1173_2 IL2_IL2R_alpha_beta_gamma_JAK1_LCK_JAK3_SHC_1act_integral_to_membrane grey red grey grey grey grey grey grey _h_4853 blue alpha4_beta1_Integrin_Fibronectin_Paxillin_trailing_edge red grey _h_5062 blue B_cell_antigen_BCR_complex_FcgammaRIIB and RasGAP grey red red blue _h_1980 alpha4_beta1_Integrin_VCAM1_Paxillin_integral_to_membrane blue _h_5170 CYLD_cytoplasm _h_5171 blue TAK1_TAB1_TAB2_integral_to_membrane red red blue _h_5174 FAK_Src_Yes_Fyn_1act_focal_adhesion_v2_Fyn_1O_1act_FAK_6O_1act or FAK_Src_Yes_Fyn_1act_focal_adhesion_v2_Src_1act_1O_FAK_6O_1act blue _h_5175 FOXA2_nucleus_v1 or HNF4_nucleus grey blue _h_4683_5 GNAI1_1act or GNAI2_1act or GNAI3_1act or GNAO1_1act or GNAZ_1act blue _h_5179 Fyn_1O_1act blue _h_4683_7 GNAI1_1act or GNAI2_1act or GNAI3_1act or GNAO1_1act or GNAZ_1act blue _h_4683_6 GNAI1_1act or GNAI2_1act or GNAI3_1act or GNAO1_1act or GNAZ_1act blue _h_4683_1 GNAI1_1act or GNAI2_1act or GNAI3_1act or GNAO1_1act or GNAZ_1act grey blue _h_4683_3 GNAI1_1act or GNAI2_1act or GNAI3_1act or GNAO1_1act or GNAZ_1act grey blue _h_6140 (IQGAP1_1p_cytoplasm or RAP1_GTP_1act) blue _h_6141 p38_alpha_1O_1O_1act_v2 or p38_beta_1O_1O_1act _h_6142 blue ETA grey _h_6144 blue (GTP_v1 and IL8_CXCR2_1act_integral_to_membrane_v1) red blue _h_6146 ( not LEF1_beta_catenin_1act_nucleus_v1) red grey blue _h_6149 Ca2__v1 or PPP2CA_PR70 red red red grey _h_2925 blue Neurocan red red red grey _h_5060 blue Dia_1act or cofilin_1ina_1p blue _h_5977_2 IL6_IL6RA_gp130__dimer__JAK1_JAK1_LMO4_Hck_1act_integral_to_membrane grey grey grey red grey grey red red grey red grey _h_6211 blue SHP2 blue _h_4574_7 EHD4_1act red red _h_3737_1 blue CARM1 and p300_nucleus and p53__tetramer__nucleus_v2 _h_3737_2 blue CARM1 and CBP_nucleus and PRMT1 grey grey grey red red red grey grey grey grey grey grey red blue _h_5896 FOXA2_nucleus_v1 red red blue _h_1084 IGF_1R_heterotetramer_IGF1_IRS1_caveola_v2 red blue _h_1086 Myb_nucleus blue _h_1087 not cortisol_GR_alpha__monomer__nucleus and (GATA3 or JUN_FOS_NFAT1_c_4_1act_nucleus) _h_1081 blue SMAD3_SMAD4_1act_nucleus and (Cbp_p300_Src_1_nucleus_Src_1_CBP_nucleus or Cbp_p300_Src_1_nucleus_Src_1_p300_nucleus) blue _h_1082 Ca2__cytoplasm or ETB_receptor_Endothelin_1_integral_to_membrane or ROCK2_1act or ROCK_1act red blue _h_807_61 FASLG_FAS__trimer__Src_Syk_1act_integral_to_membrane or TRAIL__trimer__extracellular_region blue _h_807_60 FASLG_FAS__trimer__Src_Syk_1act_integral_to_membrane or TRAIL__trimer__extracellular_region blue _h_807_63 FASLG_FAS__trimer__Src_Syk_1act_integral_to_membrane or TRAIL__trimer__extracellular_region blue _h_807_62 FASLG_FAS__trimer__Src_Syk_1act_integral_to_membrane or TRAIL__trimer__extracellular_region blue _h_807_65 FASLG_FAS__trimer__Src_Syk_1act_integral_to_membrane or TRAIL__trimer__extracellular_region grey blue _h_380_4 BRAF_14_3_3_1act_plasma_membrane_14_3_3_E_BRAF_1O_2O or BRAF_14_3_3_1act_plasma_membrane_BRAF_1O_2O_YWHAS or BRAF_14_3_3_1act_plasma_membrane_BRAF_1O_2O_YWHAZ or BRAF_14_3_3_1act_plasma_membrane_YWHAB_BRAF_1O_2O or BRAF_14_3_3_1act_plasma_membrane_YWHAG_BRAF_1O_2O or BRAF_14_3_3_1act_plasma_membrane_YWHAQ_BRAF_1O_2O or RAF1_14_3_3_1act_plasma_membrane_RAF1_1O_3O_14_3_3_E or RAF1_14_3_3_1act_plasma_membrane_RAF1_1O_3O_YWHAB or RAF1_14_3_3_1act_plasma_membrane_RAF1_1O_3O_YWHAG or RAF1_14_3_3_1act_plasma_membrane_RAF1_1O_3O_YWHAQ or RAF1_14_3_3_1act_plasma_membrane_RAF1_1O_3O_YWHAS or RAF1_14_3_3_1act_plasma_membrane_RAF1_1O_3O_YWHAZ or RAF1_BRAF_14_3_3_14_3_3_1act_plasma_membrane_v1 blue _h_807_66 FASLG_FAS__trimer__Src_Syk_1act_integral_to_membrane or TRAIL__trimer__extracellular_region red red _h_4229 blue NADE and proNGF__dimer__p75_NTR__Sortilin_1act_integral_to_membrane blue _h_4228 MYC_Max_nucleus_v2 blue _h_4227 AR_T_DHT_nucleus red grey blue _h_4224 ErbB2_ErbB3_neuregulin_1_beta_1act_integral_to_membrane_v1 _h_4223 blue FGFR4_FGF19 red grey _h_4220 blue WNT5A_4N_1S_extracellular_region grey grey grey grey grey grey blue _h_2434_63 ((EGFR_EGFR_1act_integral_to_membrane_v1 or EGFR_EGFR_EGF_EGF_GRB2_GAB1_1act_integral_to_membrane_v1) and ( not (EGFR_EGFR_1ina_integral_to_membrane or EGFR_EGFR_EGF_EGF_GRB2_GAB1_1ina_integral_to_membrane))) grey _h_4474 blue IL12B grey blue _h_2687 not HES1_TLE1_1act_nucleus blue _h_2686 (PDK1_1act_plasma_membrane or PI_3_4_5_P3_plasma_membrane) red grey red _h_2682 blue NCK1_GIT1 blue _h_2680 Src_1act_1O and not HGF_dimer__MET_dimer__GAB1_SHP2_1act_integral_to_membrane grey _h_2881 blue alphav_beta5_Integrin_integral_to_membrane blue _h_1338 Ephrin_A3_5_EPHA4_1act grey red _h_1332 blue TRAF3 _h_1333 blue cortisol_GR_alpha__dimer__1act_nucleus_v1 _h_1330 blue Ku_Artemis_DNA_PKcs__dimer__site_of_double_strand_break_v2 red grey grey blue _h_5051_14 (RAS_family_GTP_1act_plasma_membrane_H_RAS_isoform_1_GTP_v1 or RAS_family_GTP_1act_plasma_membrane_N_RAS_GTP_v1) grey grey blue _h_2886 Par6_PKC_zeta_v1 red grey blue _h_2889 IGF_1R_heterotetramer_IGF1_IRS1 grey _h_2300_2 blue p38_alpha_1O_1O_1act_v2 grey grey grey red red grey red red grey red grey grey blue _h_575 (T_DHT_AR_TIF2_CARM1_nucleus and ( not T_DHT_AR_RACK1_Src_nucleus)) red grey grey grey grey red red grey blue _h_2840 IL12_IL12R_TYK2_JAK2_1act_integral_to_membrane or IL18_IL18R_1act _h_1401 blue LKB1_nucleus and STRADA_STRADB red red grey _h_3798 blue VEGFA_homodimer_extracellular_region_v1 and VEGFR1_integral_to_membrane _h_3799 blue EGFR_integral_to_membrane and EGF_extracellular_region blue _h_3796 Ephrin_A1_EPHA1_4_1act_integral_to_membrane or Fyn_1O_1act or LYN_1act_1O or Lck_1O_1act or Src_1act_1O _h_3797 blue (GTP_v1 and ((C3G_1act or C3G_1act_cytoplasm) or CRK_I_1act_cell_leading_edge)) blue _h_3794 ((STAT5A_B__dimer__1act_nucleus or STAT5A__dimer__active_1act_nucleus_v2) or STAT5B__dimer__1act_nucleus) _h_3792 blue UNC5A_integral_to_membrane blue _h_3790 ( not COUP_TFII) _h_3791 blue (GTP_v1 and Gs_family_GDP_1ina) _h_3607 blue PDGF_BB_PDGFRB__dimer__1act_integral_to_membrane_v1 red blue _h_4543_2 ((GNAI2_GTP_1act_v1 or Pyk2_1O_1act) or S1P1_Sphingosine_1_phosphate_PDGF_BB_PDGFRB__dimer__1act_integral_to_membrane) grey blue _h_289 TAp63g__tetramer__1act_nucleus_v2 red grey red red grey _h_712 blue BARD1 blue _h_713 (AR_T_DHT_nucleus or JMJD2C) blue _h_710 SNX1 blue _h_711 ILKAP_1act blue _h_716 (( not IL6_IL6RA_gp130__dimer__JAK1_JAK1_LMO4_SOCS3_1act_integral_to_membrane) and (IFN_gamma_IFN_gammaR_JAK1_JAK1_JAK2_JAK2_1act or IL6_IL6RA_gp130__dimer__JAK1_JAK1_LMO4_1act_integral_to_membrane_v2)) red _h_714 blue alpha_catenin_cytoplasm grey blue _h_284 Fra2_ATF4_1act_nucleus red grey _h_285 blue GRB2_cytoplasm red red grey blue _h_1403 JUND__dimer__1act_nucleus _h_3248 blue VEGFR1_homodimer_plasma_membrane blue _h_3249 LPA_LPA1 grey _h_4298 blue SSAT blue _h_3240 SHP2_1act_plasma_membrane blue _h_3241 not HES1_HEY1_2_1act_nucleus blue _h_3242 dNp63a__tetramer__nucleus_v2 blue _h_3243 PKC_delta_1act_plasma_membrane _h_3244 blue DNA_replication_preinitiation_complex blue _h_3245 MIZ_1_nucleus and not MYC_Max_MIZ_1_nucleus _h_3246 blue HGF_dimer__MET_dimer__1act_integral_to_membrane_v1 _h_3247 blue Fc_epsilon_R1_FcgammaRIIB _h_2003_9 blue Syndecan_4 _h_2003_8 blue Syndecan_4 _h_2072 blue BEX1_nucleus and NGF__dimer__p75_NTR__1act_integral_to_membrane and RIP2 red blue _h_6098 (( not POU4F1_nucleus) and (((Cbp_p300_JMY_nucleus_JMY_CBP or Cbp_p300_JMY_nucleus_JMY_p300) or SP1_3_nucleus) or p53__tetramer__nucleus_v10)) _h_2003_3 blue Syndecan_4 grey _h_2003_5 blue Syndecan_4 _h_4808_2 blue PLCgamma1 _h_2003_7 blue Syndecan_4 _h_2003_6 blue Syndecan_4 blue _h_5899_11 ErbB2_ErbB3_neuregulin_1_beta_1act_integral_to_membrane_v1 blue _h_5899_10 ErbB2_ErbB3_neuregulin_1_beta_1act_integral_to_membrane_v1 blue _h_5899_13 ErbB2_ErbB3_neuregulin_1_beta_1act_integral_to_membrane_v1 _h_4295 blue ARAP1_1act or ARAP3_1act or ARHGAP4_1act or ARHGAP6_1act or ARHGAP8_1act or ARHGAP9_1act or DLC1_1act or Myosin_IXB_1act or RICS_1act or SRGAP1_1act or oligophrenin_1act or p190RhoGAP_1act or p190_B_1act blue _h_5899_15 ErbB2_ErbB3_neuregulin_1_beta_1act_integral_to_membrane_v1 blue _h_5899_14 ErbB2_ErbB3_neuregulin_1_beta_1act_integral_to_membrane_v1 blue _h_5899_17 ErbB2_ErbB3_neuregulin_1_beta_1act_integral_to_membrane_v1 blue _h_5899_16 ErbB2_ErbB3_neuregulin_1_beta_1act_integral_to_membrane_v1 blue _h_5899_19 ErbB2_ErbB3_neuregulin_1_beta_1act_integral_to_membrane_v1 blue _h_5899_18 ErbB2_ErbB3_neuregulin_1_beta_1act_integral_to_membrane_v1 grey grey grey _h_5349 blue CD40_integral_to_membrane _h_6099 blue ABRA1_1p red grey _h_3306 blue Fibronectin_extracellular_matrix _h_3301 blue SIRT1 grey grey blue _h_1105 FGFR_FGF2_complex or HGF_MET grey grey blue _h_1104 JUN_FOS_1act_nucleus_v4 red red grey red blue _h_1107 ((JUNB_Fra1_NFAT1_c_4_1act_nucleus_NFAT1_1O_7O_2s_1act_nucleus_Fra1_JUNB or JUNB_Fra1_NFAT1_c_4_1act_nucleus_NFAT4_1act_nucleus_Fra1_JUNB) or JUNB_Fra1_NFAT1_c_4_1act_nucleus_NFATc_1act_nucleus_Fra1_JUNB) grey grey grey _h_1106 blue DAB2IP_1act or GAP1M_1act or GAP1_IP4BP_1act_plasma_membrane or Neurofibromin_1act_cytoplasm or PI_4_5_P2_plasma_membrane or RasGAP_1act _h_6333 blue alpha2_beta1_Integrin_integral_to_membrane grey red blue _h_6332 TAp73a__tetramer__nucleus_v3 grey grey grey blue _h_2235 MMP2_1act or MMP9_1act grey grey grey grey red red grey grey red grey blue _h_2794_2 (((PAK2_1act or PAK4_1act) or RAS_family_GTP_1act_H_RAS_isoform_1_GTP_v1) or RAS_family_GTP_1act_N_RAS_GTP_v1) grey grey grey grey red blue _h_1459 (JUN__dimer__1act_nucleus_v3 or cortisol_GR_alpha__dimer__1act_nucleus_v1) grey blue _h_6338 Caspase_3_1act grey grey red _h_2967 blue NGF__dimer__TRKA_1act_integral_to_membrane and p62 _h_5338 blue RET9_GFRalpha1_GDNF grey blue _h_5786 Akt1_1O_1O_1act red red red grey _h_2269 blue GRB2 and Insulin_Receptor_Insulin_Shc blue _h_2308 SIRT1_nucleus _h_2309 blue KU_nucleus grey grey blue _h_2302 IFT172_1act or Kif3a_1act or Polaris or Rab23_1act or Su_fu__SIN3_HDAC_complex_nucleus _h_2303 blue 9cRA grey _h_2304 blue NRG1_extracellular_region _h_2305 blue Syndecan_1_Syntenin red _h_3989_2 blue sTNF_alpha_TNFR1A_TRADD_RIP_TRAF2_TAK1_TAB_family_1act_integral_to_membrane_TNFR1A_TRADD_TRAF2_1u_RIP_1u_TAB1_TAK1_1act_sTNF_alpha grey grey grey red blue _h_3878 CaMK_1act blue _h_3873 PAG1_1act and not PAG1_1ina red blue _h_3871 G12_G13_1act_cytoplasm or G12_GTP_1act or G12_family_GTP_1act blue _h_3870 RAC1_GTP_1act_cell_cell_junction _h_3876 blue B_cell_antigen_BCR_complex_FcgammaRIIB and RasGAP and SHIP red red grey _h_4875 blue Syndesmos blue _h_5028_2 RAC1_GTP_1act_v1 blue _h_5476 JUN__dimer__1act_nucleus_v3 blue _h_1562 ATF2_2O_1act_nucleus grey red grey grey grey grey grey blue _h_4870 ITCH or TAp73a__tetramer__nucleus_v1 blue _h_6090 p53__tetramer__nucleus_v2 grey blue _h_4183 CREB1_1act_nucleus or SMAD3_SMAD4_RUNX1_3_PEBPB2_1act_nucleus _h_4871 blue paxillin_cytoplasm grey grey red grey grey red grey blue _h_6421 SCF_KIT_1act blue _h_4312 ETA_receptor_Endothelin_1_integral_to_membrane _h_2713_1 blue SMAD5_2O_1act_cytoplasm red grey red _h_2443 blue NCAM and not ATP red red red _h_4310 blue RPA_ATR_ATRIP_RAD17_RFC2_5_9_1_1_1act_nucleus grey red _h_4317 blue Syndecan_3 grey blue _h_5099 p70S6K_1act_1p _h_4315 blue NRP2 _h_5093 blue LEF1_nucleus and PAX5_nucleus grey _h_5091 blue GRB10_plasma_membrane and p52_SHC blue _h_5090 RAC1_GTP_1act_plasma_membrane _h_5097 blue BRCA1_BARD1 blue _h_5096 (E2_ERA_nucleus or FOXA1_nucleus) grey blue _h_5094 p53__tetramer__nucleus_v2 red _h_1790 blue NOTCH2_heterodimer_integral_to_membrane blue _h_1567 PIP5K1A_1act_cell_cell_junction red grey grey blue _h_1653 Erk2_1O_1O_1act grey grey _h_1792 blue Src_1act_1O blue _h_1657 Aurora_B _h_5874 blue Gq_family and S1P2 _h_4748 blue 9cRA and PGJ2 and RXRs_PPAR grey red grey grey grey grey grey grey _h_1795 blue CBL_cytoplasm and CD2AP blue _h_5325 E_cad_CTF2_p120_catenin_Kaiso_1act_nucleus and not Kaiso_1act_nucleus blue _h_5324 dNp63a__tetramer__nucleus_v2 _h_5327 blue GRB2_cytoplasm blue _h_5326 FAK_6O_1act _h_5320 blue PinX1 _h_5323 blue Smad3_2O_1act_cytoplasm red grey blue _h_1797 Chromosomal_passenger_complex_1act_spindle_midzone _h_5328 blue HDAC3_nucleus blue _h_1435 CENP_A_1O_1act _h_1434 blue (GTP_v1 and (FAK_1O_1act_focal_adhesion or PDZRhoGEF_1O_1act_trailing_edge)) _h_6357 blue GTP_v1 and TXA2_R_family_G12_family_GDP_G_beta_gamma and not TXA2_TXA2_R_family_integral_to_membrane _h_1436 blue p300 _h_6351 blue Fibrillin_1_extracellular_matrix _h_1430 blue GFI1 and MYC_Max_MIZ_1_nucleus _h_1433 blue PIASy_nucleus blue _h_1432 E2_ERA__dimer__1act_nucleus grey blue _h_5899_51 ErbB2_ErbB3_neuregulin_1_beta_1act_integral_to_membrane_v1 _h_1439 blue E2_ER_alpha__dimer__1act_caveola _h_1438 blue Monovalent_TCR_CD3_1ina_integral_to_membrane and peptide_MHC_class_I_extracellular_region blue _h_5899_50 ErbB2_ErbB3_neuregulin_1_beta_1act_integral_to_membrane_v1 grey red red grey red blue _h_5899_52 ErbB2_ErbB3_neuregulin_1_beta_1act_integral_to_membrane_v1 red grey blue _h_3499 p70S6K_3O_4O grey _h_4943_1 blue ER_beta_1S_plasma_membrane red grey grey blue _h_3497 Gamma_Secretase_plasma_membrane_v1 blue _h_3496 SCF_KIT_1act blue _h_3491 TCF4E_beta_catenin_1act_nucleus blue _h_3490 CYLD_cytoplasm _h_3493 blue GRB2 and Gab1 and SHP2 blue _h_3492 (E2_ERA_nucleus or FOXA1_nucleus) red red blue _h_110 (AR_T_DHT_nucleus and ( not ARR19)) _h_2451 blue PKC_delta blue _h_1036_78 Arf6_GTP_1act or Arf6_GTP_1act_plasma_membrane red _h_2230_1 blue MDM2_UBCH5_nucleus grey _h_5483 blue FOXO1_1ina_1N_nucleus red grey red grey red grey red blue _h_6043_1 PDK1_1act_plasma_membrane _h_238_2 blue alpha6_beta1_Integrin blue _h_6043_2 PDK1_1act_plasma_membrane _h_4222 blue Aurora_A and TACC1 and chTOG _h_1621_1 blue IL2_IL2R_alpha_beta_gamma_JAK1_LCK_JAK3_1act_integral_to_membrane blue _h_253 ((JUN_FOSNFAT1_c_4_1act_nucleus_c_Jun_2O_NFAT1_1O_7O_2s_1act_nucleus_FOS_1O_1O or JUN_FOSNFAT1_c_4_1act_nucleus_c_Jun_2O_NFAT4_1act_nucleus_FOS_1O_1O) or JUN_FOSNFAT1_c_4_1act_nucleus_c_Jun_2O_NFATc_1act_nucleus_FOS_1O_1O) _h_3080 blue NFAT1_1ina_18O_cytoplasm grey red blue _h_2044 VEGFR2__dimer__VEGFA__dimer__VE_cadherin_beta_catenin_alpha_catenin_1act_integral_to_membrane _h_3263_11 blue E_cadherin_Ca2__beta_catenin_alpha_catenin_p120_catenin_cell_cell_junction_v1 grey blue _h_2047 p38_delta_1O_1act_1O blue _h_5051_41 (RAS_family_GTP_1act_plasma_membrane_H_RAS_isoform_1_GTP_v1 or RAS_family_GTP_1act_plasma_membrane_N_RAS_GTP_v1) grey grey _h_2041 blue FASLG_FAS__trimer__1act_integral_to_membrane grey blue _h_2901 (AR_T_DHT_nucleus and ( not TR4)) grey _h_4054 blue I_afadin_plasma_membrane blue _h_963 ( not HES1_Myb_1act_nucleus) blue _h_962 Caspase_3_1act blue _h_4050 MYC_Max_nucleus_v2 _h_964 blue BCL6_BCoR _h_967 blue POU4F2 _h_4053 blue ETO2_1act_nucleus _h_968 blue GTP_v1 and TP_alpha_Gq_family_GDP_G_beta5_gamma2 and TXA2_extracellular_region and not TXA2_TP_alpha_1ina_integral_to_membrane grey blue _h_113 ( not E2F6_DP_nucleus) grey red grey red _h_3840_3 blue CDK4_6_Cyclin_D_CDK4_Cyclin_D1 _h_3840_2 blue CDK4_6_Cyclin_D_CDK6_Cyclin_D3 grey _h_3840_4 blue CDK4_6_Cyclin_D_CDK6_Cyclin_D2 grey _h_3840_6 blue CDK4_6_Cyclin_D_CDK6_Cyclin_D1 grey blue _h_1061 PAK1_1p_1act grey red grey red red red grey red red grey red grey grey red blue _h_1065 p53__tetramer__nucleus_v2 grey red grey grey grey red _h_2681_3 blue NFATc_1act_nucleus _h_2681_2 blue EGR1_nucleus red grey red grey red _h_3263_15 blue FGFR1b_FGF3_1act _h_5199_1 blue RACO_1_1act grey grey red blue _h_385 ErbB2_ErbB3_neuregulin_1_beta_1act_integral_to_membrane_v1 _h_2894_10 blue FOXO3A_1O_1ina_2O_nucleus _h_2894_13 blue FOXO4_1O_1ina_2O_nucleus grey _h_2894_15 blue YWHAG_nucleus red grey _h_382 blue GR_cytoplasm red _h_4449 blue GAB2_1act_1O_plasma_membrane and PI3K_Class_IA_1act_plasma_membrane_v2 _h_4448 blue IL1_beta_fragment_IL1R1_IL1RAP_1act_integral_to_membrane blue _h_389 Tie2_Ang1_1act red _h_3263_16 blue FGFR1c_FGF6_1act blue _h_2434_31 ((EGFR_EGFR_1act_integral_to_membrane_v1 or EGFR_EGFR_EGF_EGF_GRB2_GAB1_1act_integral_to_membrane_v1) and ( not (EGFR_EGFR_1ina_integral_to_membrane or EGFR_EGFR_EGF_EGF_GRB2_GAB1_1ina_integral_to_membrane))) _h_5736 blue Ku70 grey blue _h_4422 MEK5_1act blue _h_2434_35 ((EGFR_EGFR_1act_integral_to_membrane_v1 or EGFR_EGFR_EGF_EGF_GRB2_GAB1_1act_integral_to_membrane_v1) and ( not (EGFR_EGFR_1ina_integral_to_membrane or EGFR_EGFR_EGF_EGF_GRB2_GAB1_1ina_integral_to_membrane))) red blue _h_2434_37 ((EGFR_EGFR_1act_integral_to_membrane_v1 or EGFR_EGFR_EGF_EGF_GRB2_GAB1_1act_integral_to_membrane_v1) and ( not (EGFR_EGFR_1ina_integral_to_membrane or EGFR_EGFR_EGF_EGF_GRB2_GAB1_1ina_integral_to_membrane))) red blue _h_2434_39 ((EGFR_EGFR_1act_integral_to_membrane_v1 or EGFR_EGFR_EGF_EGF_GRB2_GAB1_1act_integral_to_membrane_v1) and ( not (EGFR_EGFR_1ina_integral_to_membrane or EGFR_EGFR_EGF_EGF_GRB2_GAB1_1ina_integral_to_membrane))) blue _h_2434_38 ((EGFR_EGFR_1act_integral_to_membrane_v1 or EGFR_EGFR_EGF_EGF_GRB2_GAB1_1act_integral_to_membrane_v1) and ( not (EGFR_EGFR_1ina_integral_to_membrane or EGFR_EGFR_EGF_EGF_GRB2_GAB1_1ina_integral_to_membrane))) grey red grey grey red grey grey _h_3263_17 blue FGFR1c_FGF4_1act red red _h_5730 blue E2_ERA__dimer__1act_nucleus grey grey grey red red blue _h_2907 PCAF_1act_1N grey grey grey red grey _h_119 blue PP2A_B56alpha_1act red red red red red red blue _h_2944_35 not E_cadherin_cytoplasm and (MAPK_14 or p120ctn) grey grey red red grey red grey _h_4874 blue HDAC8_nucleus and PKA_1O_1act_nucleus grey grey grey red grey red grey red red _h_4432_2 blue Crk grey grey grey grey grey grey _h_4693_4 blue MCL1_mitochondrion red _h_4693_2 blue BCL2A1_mitochondrion red _h_4693_1 blue BCL_X_mitochondrion red _h_5158 blue DLX1 grey blue _h_5152 Digestive_enzymes_endosome blue _h_5153 TCPTP_p45_1p_nucleus _h_5150 blue Amphiphysin_IIB red _h_5156 blue GRB10_plasma_membrane and RET51_GFRalpha1_GDNF_v1 red blue _h_5154 (( not Fc_epsilon_R1_FcgammaRIIB_SHIP_RasGAP_p62DOK) and (((HRAS_1act or HRAS_GTP_1act_v1) or RAS_family_GTP_1act_plasma_membrane_H_RAS_isoform_1_GTP_v1) or RAS_family_GTP_1act_plasma_membrane_N_RAS_GTP_v1)) _h_5155 blue VEGFR3_integral_to_membrane red _h_6168 blue BCL10 and MALT1 and PDK1_1act_plasma_membrane _h_6169 blue GTP_v1 and not IP4 and (ARNO_1act_integral_to_membrane or Cytohesin_1_1act_integral_to_membrane or GRP1_1act_integral_to_membrane) red grey _h_1079 blue ARNT_nucleus blue _h_6162 IRAK_TRAF6_MEKK3_1act_integral_to_membrane or IRAK_TRAF6_p62_Atypical_PKCs_1act or TRAF6_TAK1_TAB1_TAB2_1act_cytoplasm_v4 _h_6160 blue SNURF grey grey blue _h_6167 ErbB4_ErbB4_neuregulin_1_beta_neuregulin_1_beta_Fyn_1act_integral_to_membrane _h_6164 blue (GTP_v1 and IL8_CXCR1_1act_integral_to_membrane_v2) blue _h_6165 FOXM1B_nucleus and not FOXM1B_p14ARF_1ina_nucleolus blue _h_411 p53__tetramer__nucleus_v2 red grey red blue _h_413 PRKACA and not SMO_1act_nonmotile_primary_cilium grey blue _h_412 STAT4__dimer__JUN_Cbp_1act_nucleus grey _h_2917_3 blue DVL1_1act red _h_2917_1 blue DAAM1_1ina red blue _h_414 p38_alpha_1O_1O_1act_v2 or p38_beta_1O_1O_1act blue _h_3770_7 (((((((ErbB2_ErbB3_neuregulin_1_beta_1act_integral_to_membrane_v3 or ErbB4_ErbB4_HBEGF_HBEGF_1act_integral_to_membrane) or ErbB4_ErbB4_neuregulin_1_beta_neuregulin_1_beta_1act_integral_to_membrane_v2) or ErbB4_ErbB4_neuregulin_2_beta_neuregulin_2_beta_1act_integral_to_membrane) or ErbB4_JM_B_ErbB4_JM_B_neuregulin_1_beta_neuregulin_1_beta_1act_integral_to_membrane_v1) or GNB1_GNG2_1act_cytoplasm) or Nephrin_NEPH1_podocin_CD2AP_membrane_raft) or Nephrin_NEPH1_podocin_membrane_raft_v1) grey grey red grey grey grey blue _h_3770_4 (((((((ErbB2_ErbB3_neuregulin_1_beta_1act_integral_to_membrane_v3 or ErbB4_ErbB4_HBEGF_HBEGF_1act_integral_to_membrane) or ErbB4_ErbB4_neuregulin_1_beta_neuregulin_1_beta_1act_integral_to_membrane_v2) or ErbB4_ErbB4_neuregulin_2_beta_neuregulin_2_beta_1act_integral_to_membrane) or ErbB4_JM_B_ErbB4_JM_B_neuregulin_1_beta_neuregulin_1_beta_1act_integral_to_membrane_v1) or GNB1_GNG2_1act_cytoplasm) or Nephrin_NEPH1_podocin_CD2AP_membrane_raft) or Nephrin_NEPH1_podocin_membrane_raft_v1) _h_4725 blue IHH_N_extracellular_region blue _h_418 ceramide grey red blue _h_4574_10 EHD4_1act red grey grey grey red red red grey grey red grey _h_1780 blue Dyskerin and Hsp90 and TERT and p23 blue _h_2519 EGF_EGFR_1act grey blue _h_2517 (NF_kappa_B1_p50_RelA_I_kappa_B_alpha_1act_cytoplasm_v2 or TNF_alpha_extracellular_region) grey blue _h_2515 AKT2_1O_1act_cytoplasm or Akt1_1O_1act_cytoplasm_v2 _h_2514 blue RasGAP _h_2513 blue JUNB_nucleus grey _h_2511 blue Fes blue _h_2510 IL12_IL12R_TYK2_JAK2_1act_integral_to_membrane or IL18_IL18R_1act _h_4552_2 blue E2F4_DP2_p107_p130_nucleus_DP2_E2F4_p130 red blue _h_807_49 FASLG_FAS__trimer__Src_Syk_1act_integral_to_membrane or TRAIL__trimer__extracellular_region blue _h_807_48 FASLG_FAS__trimer__Src_Syk_1act_integral_to_membrane or TRAIL__trimer__extracellular_region grey blue _h_807_46 FASLG_FAS__trimer__Src_Syk_1act_integral_to_membrane or TRAIL__trimer__extracellular_region blue _h_807_45 FASLG_FAS__trimer__Src_Syk_1act_integral_to_membrane or TRAIL__trimer__extracellular_region grey blue _h_807_43 FASLG_FAS__trimer__Src_Syk_1act_integral_to_membrane or TRAIL__trimer__extracellular_region blue _h_807_42 FASLG_FAS__trimer__Src_Syk_1act_integral_to_membrane or TRAIL__trimer__extracellular_region blue _h_807_41 FASLG_FAS__trimer__Src_Syk_1act_integral_to_membrane or TRAIL__trimer__extracellular_region blue _h_807_40 FASLG_FAS__trimer__Src_Syk_1act_integral_to_membrane or TRAIL__trimer__extracellular_region grey grey red red red red blue _h_4200 (( not POU4F1_nucleus) and ((POU4F2 or SP1_3_nucleus) or p53__tetramer__nucleus_v10)) grey grey blue _h_4205 Myb_nucleus _h_4204 blue E_cadherin_beta_catenin_alpha_catenin_cell_cell_junction grey _h_4206 blue HECT9 grey red grey grey red red red blue _h_2281_2 GM_CSF_extracellular_region or IL_3_extracellular_region grey red red blue _h_1350 not IL2_IL2R_1act_integral_to_membrane _h_1351 blue MYD88_TIRAP_cytoplasm blue _h_1352 p53__tetramer__nucleus_v2 red grey red _h_1356 blue Insulin_Receptor_Insuli_IRS1_GRB2_SHC red grey grey red _h_238_4 blue alpha6_beta1_Integrin blue _h_2944_37 not E_cadherin_cytoplasm and (MAPK_14 or p120ctn) _h_13 blue NEDD4_2 grey _h_10 blue IL6_IL6RA_integral_to_membrane and not PTPEC grey red red _h_2916 blue Akt1_1O_1act_plasma_membrane_v2 blue _h_4786 CDC42_GTP_1act_plasma_membrane blue _h_807_18 FASLG_FAS__trimer__Src_Syk_1act_integral_to_membrane or TRAIL__trimer__extracellular_region grey grey grey red grey red grey grey blue _h_559 (( not c_Rel) and (AR_T_DHT_nucleus or Oct_1)) grey blue _h_550 c_Abl_Arg_1act blue _h_551 SHP1_1act_2O blue _h_552 Activated_DNA or NAD grey _h_4787 blue Laminin_1 grey blue _h_556 PIP5K1C_1act or PIP5K1C_1act_cell_cell_junction red grey red grey red _h_18 blue ErbB2_ErbB3_neuregulin_1_beta_1act_integral_to_membrane_v1 red grey grey grey grey _h_5410_1 blue YWHAZ _h_232 blue G12_GDP_G_beta_gamma_1ina and PAR1_active_1act_integral_to_membrane grey grey blue _h_5051_63 (RAS_family_GTP_1act_plasma_membrane_H_RAS_isoform_1_GTP_v1 or RAS_family_GTP_1act_plasma_membrane_N_RAS_GTP_v1) blue _h_4072 PLK1_1O_1act _h_4878 blue VEGFC__dimer__extracellular_region red blue _h_3454 STIM1_1act_plasma_membrane red red grey red red grey grey _h_2868 blue VEGFR2_integral_to_membrane and VEGFR3_integral_to_membrane _h_1469 blue RXR_alpha grey grey grey grey grey blue _h_2944_51 not E_cadherin_cytoplasm and (MAPK_14 or p120ctn) red grey red red blue _h_3267 not IRF4_BCL6 and (EGR2 or IRF4_nucleus or STAT6__dimer__PARP14_1act_nucleus) grey grey grey grey blue _h_3268 (((JUN_FOSNFAT1_c_4_1act_nucleus_c_Jun_2O_NFAT1_1O_7O_2s_1act_nucleus_FOS_1O_1O or JUN_FOSNFAT1_c_4_1act_nucleus_c_Jun_2O_NFAT4_1act_nucleus_FOS_1O_1O) or JUN_FOSNFAT1_c_4_1act_nucleus_c_Jun_2O_NFATc_1act_nucleus_FOS_1O_1O) and ( not ((NFAT1_c_4_PPARG_1ina_nucleus_NFAT1_1O_7O_2s_1act_nucleus_PPARG_nucleus or NFAT1_c_4_PPARG_1ina_nucleus_NFAT4_1act_nucleus_PPARG_nucleus) or NFAT1_c_4_PPARG_1ina_nucleus_NFATc_1act_nucleus_PPARG_nucleus))) _h_3269 blue MAGP_2 blue _h_1036_110 Arf6_GTP_1act or Arf6_GTP_1act_plasma_membrane blue _h_1036_111 Arf6_GTP_1act or Arf6_GTP_1act_plasma_membrane red red grey grey red blue _h_4782 AMPKK1_active_1act_cytoplasm or AMPKK2_active_1act_cytoplasm red blue _h_5636 ( not TCF4_beta_catenin_HBP1_1ina_nucleus) red _h_5634 blue CBL and not VEGFR2__dimer__VEGFA__dimer__Myoferlin_Dynamin_2_GTP_1act_integral_to_membrane blue _h_5633 Arf6_GTP_1act grey grey _h_3250_5 blue SIK1_1O_1act_cytoplasm grey grey grey red grey blue _h_2944_58 not E_cadherin_cytoplasm and (MAPK_14 or p120ctn) grey grey grey grey _h_6177 blue alphaM_beta2_Integrin_integral_to_membrane red grey grey grey red grey red grey blue _h_5988 (TAp63g__tetramer__1act_nucleus_v2 and ( not TAp63g__tetramer__p14ARF_1ina_nucleus)) blue _h_2568 MYC_Max_nucleus_v2 grey _h_5981 blue Delta_4_integral_to_membrane blue _h_5980 ((JUN_FOSNFAT1_c_4_1act_nucleus_c_Jun_2O_NFAT1_1O_7O_2s_1act_nucleus_FOS_1O_1O or JUN_FOSNFAT1_c_4_1act_nucleus_c_Jun_2O_NFAT4_1act_nucleus_FOS_1O_1O) or JUN_FOSNFAT1_c_4_1act_nucleus_c_Jun_2O_NFATc_1act_nucleus_FOS_1O_1O) _h_6176 blue S1P4 and S1P_extracellular_region blue _h_5982 PI_3_4_5_P3 _h_5985 blue RIN_GDP_1ina and (BDNF__dimer__TRKB_1act_endosome_v2 or NGF__dimer__TRKA_1act_endosome or NT3__dimer__TRKC_1act_endosome or NT_4_5__dimer__TRKB_1act_endosome) grey blue _h_5987 ( not dNp73b__tetramer__nucleus) _h_5986 blue Ku_Artemis_DNA_PKcs__dimer__Pol_Mu_XRCC4__dimer__Ligase_IV_site_of_double_strand_break_v2 red red blue _h_736 mTORC1_PGC1A_YY1_1act_nucleus _h_737 blue RAC1_GTP_1act_plasma_membrane _h_730 blue YWHAB_cytoplasm _h_731 blue alphaIIb_beta3_Integrin_integral_to_membrane red _h_733 blue Type_VI_Collagen_extracellular_region grey grey grey grey red grey red _h_5406 blue AR_cytoplasm and RACK1 red blue _h_807_52 FASLG_FAS__trimer__Src_Syk_1act_integral_to_membrane or TRAIL__trimer__extracellular_region grey grey grey red blue _h_5051_69 (RAS_family_GTP_1act_plasma_membrane_H_RAS_isoform_1_GTP_v1 or RAS_family_GTP_1act_plasma_membrane_N_RAS_GTP_v1) red grey _h_325_1 blue (TAK1_TAB_family_TAK1_TAB2 and TGFB_TGFBR2_TGFBR1_STRAP_SMAD7_1act_integral_to_membrane) grey blue _h_6170 PKR grey blue _h_5403 (((JUN_FOSNFAT1_c_4_1act_nucleus_c_Jun_2O_NFAT1_1O_7O_2s_1act_nucleus_FOS_1O_1O or JUN_FOSNFAT1_c_4_1act_nucleus_c_Jun_2O_NFAT4_1act_nucleus_FOS_1O_1O) or JUN_FOSNFAT1_c_4_1act_nucleus_c_Jun_2O_NFATc_1act_nucleus_FOS_1O_1O) or Oct_1_nucleus) grey red blue _h_5899_39 ErbB2_ErbB3_neuregulin_1_beta_1act_integral_to_membrane_v1 red blue _h_4858 (AR_T_DHT_nucleus or beta_catenin) blue _h_4859 Akt1_1O_1O_1act blue _h_4588 PLK1_1O_1act grey _h_4587 blue Factor_XIII_1act _h_4584 blue PDGFRA_integral_to_membrane and PDGFRB_integral_to_membrane blue _h_4585 TAp73b__tetramer__nucleus blue _h_4582 Angiotensin_II_v1 and not PRL_3 red blue _h_4852 ILK_beta_parvin or ILK_gamma_parvin _h_4581 blue alphaL_beta2_Integrin_integral_to_membrane _h_1502 blue IRAK and MYD88 red blue _h_807_8 (FASLG_FAS__trimer__Src_Syk_1act_integral_to_membrane or TRAIL__trimer__extracellular_region) grey grey grey grey _h_5057 blue Dynamin_2_GTP_1act_basolateral_plasma_membrane blue _h_775 IL23_IL23R_JAK2_TYK2_1act_integral_to_membrane and not IFN_gamma_1act_extracellular_region red red _h_5055 blue uPA_uPAR_1act_plasma_membrane_v2 blue _h_1242 netrin_1_DCC_1act_integral_to_membrane grey blue _h_807_5 FASLG_FAS__trimer__Src_Syk_1act_integral_to_membrane or TRAIL__trimer__extracellular_region grey red grey red grey _h_5053 blue PI_4_5_P2_plasma_membrane and Talin grey grey _h_5052 blue sTNF_alpha_extracellular_region blue _h_252 FOXA2_nucleus_v1 blue _h_1241 RBPJ_NICD_1act_nucleus red red grey grey _h_5050 blue Exportin_1_nucleus grey blue _h_1531 CDC42_GTP_1act_plasma_membrane or RAC1_GTP_1act_plasma_membrane _h_3954 blue TNF_alpha_extracellular_region red blue _h_2527 MRN_complex_ATM_1act_site_of_double_strand_break red grey red _h_1650_6 blue p38_beta_1O_1O_1act grey _h_1650_4 blue CK2 _h_1650_5 blue CK2 grey blue _h_2185 ((AP1_1act_nucleus or SMAD2_3_SMAD4_SP1_1act_nucleus_SMAD2_2O_1act_SP1_SMAD4) or SMAD2_3_SMAD4_SP1_1act_nucleus_SP1_Smad3_2O_1act_SMAD4) grey _h_1650_1 blue CK2 blue _h_2188 LPA_LPA1 _h_2189 blue GTP_v1 and NGF__dimer__p75_NTR__1act_integral_to_membrane red grey _h_1618 blue VEGFA189__dimer__extracellular_region and VEGFR2_integral_to_membrane grey red red red grey red red grey red grey blue _h_3337_2 RHOA_GTP_1act_plasma_membrane blue _h_1614 ( not MDM4_nucleus) grey red grey red grey red _h_1964 blue SPHK2 grey blue _h_1658_9 ETA_receptor_Endothelin_1_G12_GTP_1act_integral_to_membrane or NGF__dimer__TRKA_GRIT_1act_endosome or alphaV_beta3_Integrin_Osteopontin blue _h_1658_6 ((ETA_receptor_Endothelin_1_G12_GTP_1act_integral_to_membrane or NGF__dimer__TRKA_GRIT_1act_endosome) or alphaV_beta3_Integrin_Osteopontin) blue _h_1658_7 ETA_receptor_Endothelin_1_G12_GTP_1act_integral_to_membrane or NGF__dimer__TRKA_GRIT_1act_endosome or alphaV_beta3_Integrin_Osteopontin blue _h_1658_4 ETA_receptor_Endothelin_1_G12_GTP_1act_integral_to_membrane or NGF__dimer__TRKA_GRIT_1act_endosome or alphaV_beta3_Integrin_Osteopontin blue _h_1658_5 ETA_receptor_Endothelin_1_G12_GTP_1act_integral_to_membrane or NGF__dimer__TRKA_GRIT_1act_endosome or alphaV_beta3_Integrin_Osteopontin blue _h_1658_2 ((ETA_receptor_Endothelin_1_G12_GTP_1act_integral_to_membrane or NGF__dimer__TRKA_GRIT_1act_endosome) or alphaV_beta3_Integrin_Osteopontin) blue _h_1658_3 ETA_receptor_Endothelin_1_G12_GTP_1act_integral_to_membrane or NGF__dimer__TRKA_GRIT_1act_endosome or alphaV_beta3_Integrin_Osteopontin red red red red _h_1960 blue SDF1_CXCR4_1act_integral_to_membrane grey _h_1985 blue SOCS1 blue _h_1632 PHD1_3_OS9_OS9_PHD2 or PHD1_3_OS9_OS9_PHD3 _h_1631 blue Ron_MSP and alphaM_beta2_Integrin blue _h_1630 PAP or PAP_2a_1act blue _h_1637 RAC1_CDC42_GTP_1act red _h_1635 blue HRAS_plasma_membrane and RACK1 and RasGAP _h_1634 blue RHOGDI blue _h_2146 MRN_complex_ATM_1act_site_of_double_strand_break red _h_1989 blue EPO_EPOR__dimer_ and Jak2 and not (LNK_plasma_membrane or SHP1_1act) blue _h_1988 Ca2__cytoplasm red blue _h_3855 WWP1 grey red blue _h_3856 JUN_FOS_1act_nucleus_v3 _h_3851 blue TR2_nucleus blue _h_5744_1 CaM_Ca2__Calcineurin_A_alpha_beta_B1_1act_v1 grey red grey grey red blue _h_3858 Arf6_GTP_1act_cell_cell_junction blue _h_1036_85 Arf6_GTP_1act or Arf6_GTP_1act_plasma_membrane grey blue _h_2725 (NFATc_1act_nucleus and ( not cortisol_GR_alpha__monomer__nucleus)) grey grey blue _h_2721 MEF2D_NFAT1_Cbp_p300_NFAT1_1O_4O_2s_1act_nucleus_MEF2D_nucleus_CBP_nucleus or MEF2D_NFAT1_Cbp_p300_NFAT1_1O_4O_2s_1act_nucleus_MEF2D_nucleus_p300_nucleus grey grey blue _h_2728 IL23_IL23R_JAK2_TYK2_1act_integral_to_membrane grey blue _h_5479_1 CK1_epsilon_cytoplasm red grey grey blue _h_3379 PI_4_5_P2_plasma_membrane _h_1189 blue RPA_ATR_ATRIP_RAD17_RFC2_5_9_1_1_TopBP1_CEP164_1act_nucleus blue _h_1188 Erk2_1O_1O_1act red blue _h_1185 LEF1_beta_catenin_1act_nucleus_v1 blue _h_1184 p53__tetramer__nucleus_v2 blue _h_1187 ( not AP1_nucleus) _h_1186 blue GRB2_cytoplasm blue _h_1181 TCPTP_p45_cytoplasm _h_4594_3 blue Erk2_1O_1O_1act _h_1183 blue ErbB4_ErbB4_HBEGF_HBEGF_1act_integral_to_membrane and Jak2 grey grey grey red grey blue _h_807_36 FASLG_FAS__trimer__Src_Syk_1act_integral_to_membrane or TRAIL__trimer__extracellular_region blue _h_2141 beta_catenin_nucleus grey grey blue _h_807_34 FASLG_FAS__trimer__Src_Syk_1act_integral_to_membrane or TRAIL__trimer__extracellular_region grey grey blue _h_807_35 FASLG_FAS__trimer__Src_Syk_1act_integral_to_membrane or TRAIL__trimer__extracellular_region grey grey grey blue _h_807_32 FASLG_FAS__trimer__Src_Syk_1act_integral_to_membrane or TRAIL__trimer__extracellular_region red red blue _h_46 GD3 or ceramide or p53_1act_mitochondrion red red red grey grey blue _h_4277 RAC1_GTP_1act_plasma_membrane grey red grey _h_1617 blue PDGF_CC_1act_extracellular_region grey grey blue _h_5068 Ca2__cytoplasm or DAG_v1 grey blue _h_2704 not Rab23_1act and (Akt1_1O_1O_1act_cytoplasm or IFT172_1act or Kif3a_1act or MEK1_2O_1act or PKC_delta_1act or Polaris or SHH_Np_Cholesterol_CDO_1act_extracellular_region or SMO_beta_Arrestin2_1act_clathrin_coat_of_coated_pit) grey _h_5665_2 blue SHBG_integral_to_membrane grey _h_5665_1 blue SHBG_integral_to_membrane _h_5918 blue IL18Rbeta_integral_to_membrane red _h_5548 blue CENTA1_cytoplasm grey grey blue _h_5919 (FOXO3A_1O_2O_nucleus and ( not FOXO3A_SIRT1_1act_nucleus)) blue _h_109 p70S6K_1act_1p blue _h_807_38 FASLG_FAS__trimer__Src_Syk_1act_integral_to_membrane or TRAIL__trimer__extracellular_region _h_5917 blue RB1_E2F4_DP_nucleus _h_3455_3 blue YWHAQ grey grey _h_2701 blue Myb_nucleus _h_2312_1 blue SMAD2_3_SMAD4_nucleus_Smad3_2O_1act_SMAD4 grey grey grey blue _h_515_2 (IL2_IL2R_alpha_beta_gamma_JAK1_LCK_JAK3_1act_integral_to_membrane or IL4_IL4R_JAK1_IL2R_gamma_JAK3_1act_integral_to_membrane) and not (IL2R_beta_JAK1_LCK_SOCS1_1act_integral_to_membrane or IL2R_beta_JAK1_LCK_SOCS3_1act_integral_to_membrane) blue _h_4078 EPO_EPOR__dimer__JAK2 or EPO_EPOR__dimer__LYN blue _h_4079 TNF_alpha_TNFR1A_TRADD_MADD_cIAP2_RIP_TRAF2_RAIDD_PIDD blue _h_943 ((AIB1_nucleus or E2_ERA_nucleus) or FOXA1_nucleus) blue _h_3130_1 CRIPTO_GPC1_1act_plasma_membrane blue _h_4074 B_cell_antigen_BCR_complex_LYN_SYK_BLNK or Blk_1O_1act_plasma_membrane or CD19_1act_1O or EPO_EPOR__dimer__JAK2 or Fgr_1act_1O_plasma_membrane or Fyn_1act_1O_plasma_membrane or Hck_1act_1O_plasma_membrane or LYN_1O_1act_plasma_membrane or Lck_1O_1act_plasma_membrane or Src_1O_1act_plasma_membrane or Yes_1act_1O_plasma_membrane blue _h_940 FOXM1C_2O_1act_nucleus blue _h_947 beta_TrCP1_SCF blue _h_946 Fer_1act_1O_cell_cell_junction _h_945 blue Dok4 _h_5913 blue JUND_nucleus blue _h_2234 JUNB_FOS_1act_nucleus blue _h_3130_3 CRIPTO_GPC1_1act_plasma_membrane grey blue _h_1485 FOXA2_nucleus_v1 or HNF1A__dimer__nucleus grey blue _h_3130_2 CRIPTO_GPC1_1act_plasma_membrane red grey blue _h_445 ((AR_T_DHT_nucleus or BRM_BAF57) or hZIMP7) _h_29_3 blue 9cRA and Cbp_p300_PCAF_nucleus_PCAF_p300 and TIF2 _h_29_2 blue 9cRA and Cbp_p300_PCAF_nucleus_PCAF_CBP and RAR_alpha red _h_29_4 blue 9cRA and RAR_alpha and TIF2 grey grey grey grey blue _h_1036_116 Arf6_GTP_1act or Arf6_GTP_1act_plasma_membrane grey grey blue _h_1610 JUN_FOS_1act_nucleus_v2 grey red grey grey grey grey grey grey red blue _h_3285 TCPTP_p45_1p_nucleus or eIF2A_1O grey red red red red grey _h_6399 blue PGC1A_1N_nucleus red grey _h_5128 blue paxillin_cytoplasm grey grey red grey grey _h_4667 blue NDEL1_Katanin_60 blue _h_4469 TAp63a__tetramer__1act_nucleus_v3 blue _h_4468 (( not GRAIL) and ((JUN_FOSNFAT1_c_4_1act_nucleus_c_Jun_2O_NFAT1_1O_7O_2s_1act_nucleus_FOS_1O_1O or JUN_FOSNFAT1_c_4_1act_nucleus_c_Jun_2O_NFAT4_1act_nucleus_FOS_1O_1O) or JUN_FOSNFAT1_c_4_1act_nucleus_c_Jun_2O_NFATc_1act_nucleus_FOS_1O_1O)) grey _h_4465 blue Telomerase blue _h_2434_12 ((EGFR_EGFR_1act_integral_to_membrane_v1 or EGFR_EGFR_EGF_EGF_GRB2_GAB1_1act_integral_to_membrane_v1) and ( not (EGFR_EGFR_1ina_integral_to_membrane or EGFR_EGFR_EGF_EGF_GRB2_GAB1_1ina_integral_to_membrane))) _h_4467 blue Plexin_D1_Nrp1_integral_to_membrane _h_4466 blue BRCA1 grey grey red blue _h_4462 CDC42_GTP_1act_plasma_membrane red red red red blue _h_1716 ATF2__dimer__1act_nucleus grey grey grey blue _h_6392 Bam32_HPK1 or Rac1_1act or TAK1_1act grey grey grey _h_6394 blue Caveolin_1 red grey grey red blue _h_2023 FBXO8_plasma_membrane grey grey grey red red red _h_540_1 blue CDK2_Cyclin_A_nucleus grey blue _h_5845 RHOA_GTP_1act_plasma_membrane blue _h_5846 Erk2_1O_1O_1act _h_5847 blue alphaD_beta2_Integrin_integral_to_membrane grey grey grey grey blue _h_2022 MSK1_2_active_1act _h_5849 blue SCF_ubiquitin_ligases_v1 and TCF4_beta_catenin_1act_nucleus blue _h_1036_49 Arf6_GTP_1act or Arf6_GTP_1act_plasma_membrane red grey red _h_5036 blue IL5RA_JAK2 grey blue _h_1036_40 Arf6_GTP_1act or Arf6_GTP_1act_plasma_membrane blue _h_1036_43 Arf6_GTP_1act or Arf6_GTP_1act_plasma_membrane blue _h_1036_42 Arf6_GTP_1act or Arf6_GTP_1act_plasma_membrane blue _h_1036_45 Arf6_GTP_1act or Arf6_GTP_1act_plasma_membrane grey blue _h_1036_47 Arf6_GTP_1act or Arf6_GTP_1act_plasma_membrane blue _h_1036_46 Arf6_GTP_1act or Arf6_GTP_1act_plasma_membrane red grey grey _h_3892 blue alphaM_beta2_Integrin_integral_to_membrane grey _h_2075_1 blue FOXO3A_1O_1O_nucleus and FOXO3A_1O_2O_nucleus grey grey blue _h_3115 Importin_beta or NUP153 or NUP214 or importin_alpha blue _h_3116 Erk2_1O_1O_1act _h_3117 blue (GTP_v1 and IL8_CXCR1_1act_integral_to_membrane_v2) blue _h_3111 Digestive_enzymes_endosome blue _h_3112 PKC_epsilon grey grey grey blue _h_4854 p38_alpha_1O_1O_1act_v2 grey red grey grey grey grey grey _h_5201 blue IRS1_NCK2_cytoplasm grey grey _h_5894 blue ATM_1act_nucleus grey blue _h_482 PLK1 _h_3263_37 blue FGFR1b_FGF2_1act red grey grey red grey red grey blue _h_4547 TAp63b__tetramer__1act_nucleus_v1 grey grey blue _h_4544 RET51_GFRalpha1_GDNF_v1 or RhoA_1act red red blue _h_4545 netrin_1_DCC_FAK_Fyn_1act_integral_to_membrane_v4 grey blue _h_5207 ( not MYC_Max_nucleus_v4) grey _h_3701 blue CaM grey grey grey blue _h_5899_55 ErbB2_ErbB3_neuregulin_1_beta_1act_integral_to_membrane_v1 grey grey red grey grey grey red blue _h_2539 Erk2_1O_1O_1act grey grey _h_1057 blue B_cell_antigen_extracellular_region red red _h_2531 blue Osteopontin_extracellular_region grey blue _h_2533 ROCK1_1act_cell_cell_junction grey blue _h_2535 ATM_1O_1act _h_2534 blue LPA_LPA1_2_3_LPA1_plasma_membrane_LPA or LPA_LPA1_2_3_LPA2_plasma_membrane_LPA or LPA_LPA1_2_3_LPA3_plasma_membrane_LPA or PKC_delta_1act_plasma_membrane blue _h_2537 (ETS1_nucleus or JUN_FOS_1act_nucleus_v4) _h_2536 blue GTP_v1 and (BDNF__dimer__TRKB_1act_endosome_v2 or NGF__dimer__TRKA_1act_endosome or NT3__dimer__TRKC_1act_endosome or NT_4_5__dimer__TRKB_1act_endosome) grey blue _h_4262 proBDNF__dimer__p75_NTR__Sortilin_TRAF6_NRIF_1act_integral_to_membrane blue _h_807_27 FASLG_FAS__trimer__Src_Syk_1act_integral_to_membrane or TRAIL__trimer__extracellular_region grey grey _h_4266 blue CSF2RB__dimer__integral_to_membrane blue _h_807_23 FASLG_FAS__trimer__Src_Syk_1act_integral_to_membrane or TRAIL__trimer__extracellular_region blue _h_807_22 FASLG_FAS__trimer__Src_Syk_1act_integral_to_membrane or TRAIL__trimer__extracellular_region red grey grey blue _h_807_28 FASLG_FAS__trimer__Src_Syk_1act_integral_to_membrane or TRAIL__trimer__extracellular_region blue _h_4855 TAp63g__tetramer__1act_nucleus_v2 _h_3400_1 blue N_WASP grey red grey grey blue _h_1043_2 not SLAP and (CSK_1act_plasma_membrane or PDGF_BB_PDGFRB__dimer__1act_integral_to_membrane_v1) red blue _h_1043_4 not SLAP and (CSK_1act_plasma_membrane or PDGF_BB_PDGFRB__dimer__1act_integral_to_membrane_v1) red blue _h_1043_6 not SLAP and (CSK_1act_plasma_membrane or PDGF_BB_PDGFRB__dimer__1act_integral_to_membrane_v1) red blue _h_1043_8 not SLAP and (CSK_1act_plasma_membrane or PDGF_BB_PDGFRB__dimer__1act_integral_to_membrane_v1) grey grey red grey red _h_1171_2 blue JIP3 _h_378 blue HGF_dimer__MET_dimer__1act_integral_to_membrane_v1 blue _h_379 HIF1A_ARNT_nucleus grey _h_425_2 blue CBP_nucleus and PTGES2 red _h_5276 blue ELK1_1O_4O_1act_nucleus grey grey blue _h_5275 CDK5R1_CDK5_1act red _h_2062_2 blue RAC1_CDC42_GTP_1act_plasma_membrane blue _h_374 dNp63g__tetramer__nucleus blue _h_4764 CBL_dimer__1act _h_5274 blue ICAM2 grey red red grey blue _h_2637_2 GNB1_GNG2_1act_cytoplasm or PDGF_BB_PDGFRB__dimer__1act_integral_to_membrane_v1 or SDF1_CXCR4_JAK2_1act_integral_to_membrane grey grey red grey grey blue _h_805 ErbB2_ErbB3_neuregulin_1_beta_1act_integral_to_membrane_v3 grey blue _h_4683_9 GNAI1_1act or GNAI2_1act or GNAI3_1act or GNAO1_1act or GNAZ_1act red blue _h_802 NFAT1_FOXP3 blue _h_3676 ((STAT5A_B__dimer__1act_nucleus or STAT5A__dimer__active_1act_nucleus_v2) or STAT5B__dimer__1act_nucleus) grey red blue _h_5051_40 (RAS_family_GTP_1act_plasma_membrane_H_RAS_isoform_1_GTP_v1 or RAS_family_GTP_1act_plasma_membrane_N_RAS_GTP_v1) red grey grey blue _h_372 RHOA_GTP_1act_trailing_edge _h_373 blue p53__tetramer__nucleus_v2 red _h_626 blue alpha4_beta1_Integrin_VCAM1_Paxillin_integral_to_membrane red red grey red blue _h_627 EPO_EPOR__dimer__JAK2 red red blue _h_156 PRAK_1O_1act or p38alpha_beta_MAPKAPK2_1act_MAPKAPK2_4O_1O_p38_alpha_1O_1O_1act_v2 or p38alpha_beta_MAPKAPK2_1act_MAPKAPK2_4O_1O_p38_beta_1O_1O_1act or p38alpha_beta_MAPKAPK3_1act_MAPKAPK3_3O_1O_p38_alpha_1O_1O_1act_v2 or p38alpha_beta_MAPKAPK3_1act_p38_beta_1O_1O_1act_MAPKAPK3_3O_1O _h_3872 blue (Gi_family_GNB1_GNG2_GDP_1ina and PAR1_active_1act_integral_to_membrane) grey _h_157 blue HEY1_nucleus grey blue _h_2637_8 GNB1_GNG2_1act_cytoplasm or PDGF_BB_PDGFRB__dimer__1act_integral_to_membrane_v1 or SDF1_CXCR4_JAK2_1act_integral_to_membrane _h_5278 blue TAp63b__tetramer__1act_nucleus_v1 grey blue _h_151 Alpha_Synuclein__Aggregates_ grey red blue _h_620 dNp63a__tetramer__nucleus_v2 grey red _h_621 blue VEGFR3_VEGFD_1act_plasma_membrane grey _h_2084_1 blue CDC25B_1ina_1O blue _h_1372 IL2_IL2R_alpha_beta_gamma_JAK1_LCK_JAK3_1act_integral_to_membrane or MEK1_1act_cytoplasm or MEK2_1act_cytoplasm blue _h_1371 (CEBPB__dimer_ or STAT5__dimer__active_HDAC1_1act_nucleus) _h_6157 blue Fra2_1O_1O_nucleus blue _h_1377 MYC_Max_nucleus_v2 blue _h_1374 NF_kappa_B1_RelA_1act_nucleus red grey blue _h_1378 Blk_1O_1act_plasma_membrane or Fgr_1act_1O_plasma_membrane or Fyn_1act_1O_plasma_membrane or Hck_1act_1O_plasma_membrane or LYN_1O_1act_plasma_membrane or Lck_1O_1act_plasma_membrane or Src_1O_1act_plasma_membrane or Yes_1act_1O_plasma_membrane _h_1379 blue FZD2_integral_to_membrane and ROR2_integral_to_membrane _h_6062 blue FOXM1B_nucleus red grey _h_2493_2 blue p38_alpha_1O_1O_1act_v2 grey _h_2493_1 blue MAPKAPK3 red blue _h_6060 SNX1_endosome and not SNX1_SNX2 blue _h_318 FOXM1B_nucleus blue _h_1036_136 Arf6_GTP_1act or Arf6_GTP_1act_plasma_membrane red red blue _h_1036_135 Arf6_GTP_1act or Arf6_GTP_1act_plasma_membrane _h_3288 blue GRB2 and Insulin_Receptor_Insulin_IRS1 and SHIP_2O _h_3289 blue Caspase_8 and c_FLIPS grey grey red grey blue _h_3286 Lethal_Factor_cytoplasm or TNF_alpha_extracellular_region blue _h_3287 (AR_T_DHT_nucleus and ( not SCP2)) blue _h_3280 MIZ_1_IRF8_nucleus or SPI1_nucleus blue _h_3281 PKC_alpha_1act blue _h_1036_138 Arf6_GTP_1act or Arf6_GTP_1act_plasma_membrane blue _h_1036_139 Arf6_GTP_1act or Arf6_GTP_1act_plasma_membrane grey red grey _h_5611 blue ATM_3O_1N_site_of_double_strand_break grey _h_5613 blue IL5_IL5RA_CSF2RB__hexamer__JAK2_JAK2_SHP2_1act grey red _h_5614 blue Par3_integral_to_membrane grey grey blue _h_532 CaM_Ca2__Calcineurin_A_alpha_beta_B1_1act_v2 red _h_3026_3 blue Ephrin_B1_integral_to_membrane blue _h_531 Exportin_1_1act grey grey blue _h_534 RhoA_1act blue _h_535 TAp63g__tetramer__1act_nucleus_v2 red blue _h_6068 HIF1A_ARNT_nucleus blue _h_4683_4 GNAI1_1act or GNAI2_1act or GNAI3_1act or GNAO1_1act or GNAZ_1act red blue _h_5051_45 (RAS_family_GTP_1act_plasma_membrane_H_RAS_isoform_1_GTP_v1 or RAS_family_GTP_1act_plasma_membrane_N_RAS_GTP_v1) red grey grey blue _h_1373_3 GNB1_GNG2_1act_cytoplasm blue _h_1373_1 GNB1_GNG2_1act_cytoplasm grey red blue _h_4950 JUND_FOS_1act_nucleus grey red red _h_3194 blue Midkine_extracellular_region _h_2882 blue ARNO_cytoplasm and EGFR_EGFR_EGF_EGF_integral_to_membrane_v2 _h_2884 blue PP32 blue _h_2887 Insulin_Receptor_Insulin_GRB14_PDK1 _h_3195 blue NGF__dimer__p75_NTR__TRAF6_RIP2_IRAK_1act_integral_to_membrane and p62 grey red red red blue _h_4543_4 ((GNAI2_GTP_1act_v1 or Pyk2_1O_1act) or S1P1_Sphingosine_1_phosphate_PDGF_BB_PDGFRB__dimer__1act_integral_to_membrane) _h_288 blue alpha9_beta1_Integrin_integral_to_membrane blue _h_4543_3 ((GNAI2_GTP_1act_v1 or Pyk2_1O_1act) or S1P1_Sphingosine_1_phosphate_PDGF_BB_PDGFRB__dimer__1act_integral_to_membrane) blue _h_4543_1 ((GNAI2_GTP_1act_v1 or Pyk2_1O_1act) or S1P1_Sphingosine_1_phosphate_PDGF_BB_PDGFRB__dimer__1act_integral_to_membrane) red red blue _h_286 PLK1_PBIP1_kinetochore _h_287 blue DAX_1_cytoplasm _h_280 blue HC8_Proteasome_subunit_alpha blue _h_281 PLK1_1O_1act _h_282 blue EPOR_plasma_membrane grey grey red red grey grey red grey blue _h_1043_3 not SLAP and (CSK_1act_plasma_membrane or PDGF_BB_PDGFRB__dimer__1act_integral_to_membrane_v1) red grey grey red grey _h_4876 blue NCK1_cytoplasm and Tie2_Ang1_1act blue _h_4877 FAK_1O_1act_focal_adhesion red grey _h_4872 blue DP97 red red grey _h_4941 blue coatomer_protein_complex_ARF1_GTP_Golgi_to_ER_transport_vesicle_membrane red grey blue _h_393 IL2_IL2R_1act_integral_to_membrane blue _h_2414 STAT4__dimer__1act_nucleus_v2 grey grey blue _h_5899_58 ErbB2_ErbB3_neuregulin_1_beta_1act_integral_to_membrane_v1 grey blue _h_5899_54 ErbB2_ErbB3_neuregulin_1_beta_1act_integral_to_membrane_v1 blue _h_5899_57 ErbB2_ErbB3_neuregulin_1_beta_1act_integral_to_membrane_v1 grey grey grey blue _h_5899_53 ErbB2_ErbB3_neuregulin_1_beta_1act_integral_to_membrane_v1 red grey _h_1527 blue alpha9_beta1_Integrin_integral_to_membrane grey grey red blue _h_4954 FAK_1act_1O or FAK_Src_Yes_Fyn_1act_focal_adhesion_v2_Fyn_1O_1act_FAK_6O_1act or FAK_Src_Yes_Fyn_1act_focal_adhesion_v2_Src_1act_1O_FAK_6O_1act grey red red grey grey red grey blue _h_3725 (PLCgamma1_3O_1act_cytoplasm or Src_1act) red red grey grey _h_3936 blue ILK_ELMO2 red blue _h_2809 CaM_Ca2_ _h_1448 blue TCR_CD3_MHC_II_CD4_LCK_1act_integral_to_membrane grey blue _h_3973_2 LPA_LPA2 or LPA_LPA3 blue _h_1043_7 not SLAP and (CSK_1act_plasma_membrane or PDGF_BB_PDGFRB__dimer__1act_integral_to_membrane_v1) grey red grey grey blue _h_3973_1 LPA_LPA2 or LPA_LPA3 red grey red blue _h_17 ETS1_1act_1p_nucleus blue _h_14 Ca2__cytoplasm or DAG_v2 or VEGFR3_VEGFC_D_1act red blue _h_12 Caspase_3_1act grey grey _h_11 blue FOSB_nucleus red grey blue _h_2561 (AR_T_DHT_nucleus and ( not HBO1)) red grey red blue _h_4010 TAp63g__tetramer__1act_nucleus_v2 red grey blue _h_5138 p38_alpha_1O_1O_1act_v2 or p38_beta_1O_1O_1act red blue _h_4012 E2_ER_alpha__dimer__PELP1_Src_PI3K_1act_caveola or E2_ER_alpha__dimer__Striatin_1act_plasma_membrane or PI3K_1act_plasma_membrane_v2 or PI_3_4_5_P3_plasma_membrane blue _h_4225 PDK1 or PDK1_1O_1act or PDK1_1O_1act_plasma_membrane or PI_3_4_5_P3_plasma_membrane grey blue _h_4070 SIRT1_nucleus grey blue _h_4015 Dynamin_2_GTP_1act red red grey grey _h_5059 blue alpha6_beta1_Integrin_integral_to_membrane blue _h_5058 JUN_FOS_1act_nucleus_v4 red red red grey blue _h_807_2 FASLG_FAS__trimer__Src_Syk_1act_integral_to_membrane or TRAIL__trimer__extracellular_region blue _h_807_3 FASLG_FAS__trimer__Src_Syk_1act_integral_to_membrane or TRAIL__trimer__extracellular_region grey red blue _h_5137 p53__tetramer__nucleus_v2 blue _h_1619 Ca2__cytoplasm or PDGF_BB_PDGFRB__dimer__PLCgamma1_1act_integral_to_membrane_v1 grey grey grey blue _h_1967 RSK2_1O_1act grey _h_1965 blue SHC_1O_1O_1act grey grey _h_1962 blue SMAD3_SMAD4_1act_nucleus blue _h_1613 STAT6__dimer__1act_nucleus_v1 grey blue _h_4 JUND_FOS_1act_nucleus _h_5 blue IL3_IL3RA_integral_to_membrane blue _h_6 (E2F1_DP_nucleus_v4 and ( not ((RB1_E2F1_3_DP_nucleus_v1_DP1_E2F1_RB1_2O or RB1_E2F1_3_DP_nucleus_v1_DP1_E2F3_RB1_2O) or RB1_E2F1_3_DP_nucleus_v1_DP1_RB1_2O_E2F2))) blue _h_7 PI3K_1act_plasma_membrane_v2 blue _h_1 (BRCA1 or FOXA1_nucleus) blue _h_3 Tie2_Ang1_1act_caveola or Tie2_Ang2 _h_5133 blue PITX2_nucleus _h_8 blue TRAF6 blue _h_9 Crk_1act_cell_cell_junction _h_3933 blue GTP_v1 and Src_1act_1O _h_3092_5 blue PP2A_1act_v1 grey blue _h_2708 Erk1_1O_1act_1O_cytoplasm blue _h_2709 TAp63b__tetramer__1act_nucleus_v1 _h_2706 blue Ephrin_B1_integral_to_membrane _h_2707 blue SHP2 _h_1370_2 blue SKP2 red red _h_2703 blue (LPS and MEKK3) blue _h_2700 PIP5K1C_1act_synaptic_vesicle_membrane red blue _h_2432 TAp73a__tetramer__nucleus_v3 blue _h_1739 NRDP1 _h_2864 blue MEK2_cytoplasm and RAF1_1O_1O_1act_cytoplasm grey _h_4661 blue RAB3GAP2_RIMS1_UNC13B and SNAP25_1act and SNAP25_fragment_1_1act and VAMP2_1act and not (STXIA_STXBP1 or VAMP2_and_STX1A_fragments) grey grey red red grey blue _h_6398 HIF1A_ARNT_nucleus red grey _h_6391 blue MYHC2A and RHOA_GTP_1act _h_1383 blue Nephrin_NEPH1_cell_cell_junction _h_6393 blue IL2R_gamma_integral_to_membrane and TCR_CD3_MHC_I_CD8_1act_integral_to_membrane _h_2132 blue LPA1_plasma_membrane blue _h_6395 Arf6_GTP_1act blue _h_4856 ATF2__dimer__ER_alpha_1act_nucleus blue _h_6396 FAS_FADD_DAXX_Ask1_Caspase_8_Caspase_8_FASLG grey _h_6104 blue Antigen_IgE_Fc_epsilon_R1 and GADs and GRB2 and LAT_1act and PLCgamma1 red grey blue _h_6105 EGR1_1act red blue _h_1888 (( not NICD_nucleus) and (((((((Erk1_1act_nucleus or Erk2_1act_nucleus) or ILK_1act) or Jnk1_1O_1act_1O_nucleus) or LPA_LPA1_2_3_LPA1_plasma_membrane_LPA) or LPA_LPA1_2_3_LPA2_plasma_membrane_LPA) or LPA_LPA1_2_3_LPA3_plasma_membrane_LPA) or NAKED)) grey blue _h_1730 ((PML_YAP1 or TAp73a__tetramer__nucleus_v3) or p300) red blue _h_6100 PI3K_cytoplasm _h_4857 blue Exo70_SEPT2 and not CDC42_GTP_IQGAP1_1act grey blue _h_1737 VEGF_Rho_ROCK_alphav_beta3_Integrin_1act_plasma_membrane grey grey grey blue _h_2698 (AR_T_DHT_nucleus or JHDM2A) red grey _h_1887 blue Laminin_4 grey grey grey red red red grey grey grey _h_2874_4 blue FAK_Src_Yes_Fyn_Paxillin_1act_focal_adhesion_Src_1act_1O_paxillin_2O_FAK_6O_1act grey _h_4851 blue ErbB4_CYT2_integral_to_membrane red grey grey grey grey grey red _h_2874_3 blue FAK_Src_Yes_Fyn_Paxillin_1act_focal_adhesion_paxillin_2O_Fyn_1O_1act_FAK_6O_1act _h_4018 blue Ephrin_A5_integral_to_membrane blue _h_4019 SRF_dimer__MAL_dimer__1act_nucleus blue _h_1353 (TAp63g__tetramer__p300_1act_nucleus and ( not TAp63g__tetramer__NIR_nucleus)) blue _h_1036_98 Arf6_GTP_1act or Arf6_GTP_1act_plasma_membrane red grey _h_4013 blue mTORC1_1act _h_4014 blue Insulin_Receptor_Insulin_v2 and PP1_gamma grey blue _h_4016 CDC42_GTP_1act_plasma_membrane blue _h_4017 voltage_gated_calcium_channel_complex_1act _h_3092_1 blue PP2A_1act_v1 _h_3092_2 blue PP2A_1act_v1 _h_3092_3 blue PP2A_1act_v1 _h_3092_4 blue PP2A_1act_v1 grey _h_3092_6 blue PP2A_1act_v1 grey grey red grey _h_3015 blue Pyk2_RAFTK_cytoplasm and Src_1act_1O and p130Cas and (Ca2__cytoplasm or PKC_beta_1act_plasma_membrane or PKC_delta_1act_plasma_membrane or PKC_epsilon_1act_plasma_membrane or PKC_isoenzymes_1act_plasma_membrane or PKC_theta_1act_plasma_membrane or PRKCG_1act_plasma_membrane or PRKCH_1act_plasma_membrane) grey red blue _h_3014 p53__tetramer__nucleus_v2 grey grey red grey grey blue _h_2805 ((JUN_FOSNFAT1_c_4_1act_nucleus_c_Jun_2O_NFAT1_1O_7O_2s_1act_nucleus_FOS_1O_1O or JUN_FOSNFAT1_c_4_1act_nucleus_c_Jun_2O_NFAT4_1act_nucleus_FOS_1O_1O) or JUN_FOSNFAT1_c_4_1act_nucleus_c_Jun_2O_NFATc_1act_nucleus_FOS_1O_1O) grey red red grey blue _h_1638 ( not MYC_Max_MIZ_1_nucleus) grey grey red grey grey red grey grey grey grey red blue _h_2647 Lethal_Factor_cytoplasm red blue _h_4190 (FOXM1B_nucleus and ( not FOXM1B_p14ARF_1ina_nucleolus)) grey blue _h_2434_79 ((EGFR_EGFR_1act_integral_to_membrane_v1 or EGFR_EGFR_EGF_EGF_GRB2_GAB1_1act_integral_to_membrane_v1) and ( not (EGFR_EGFR_1ina_integral_to_membrane or EGFR_EGFR_EGF_EGF_GRB2_GAB1_1ina_integral_to_membrane))) blue _h_2434_78 ((EGFR_EGFR_1act_integral_to_membrane_v1 or EGFR_EGFR_EGF_EGF_GRB2_GAB1_1act_integral_to_membrane_v1) and ( not (EGFR_EGFR_1ina_integral_to_membrane or EGFR_EGFR_EGF_EGF_GRB2_GAB1_1ina_integral_to_membrane))) blue _h_2434_75 ((EGFR_EGFR_1act_integral_to_membrane_v1 or EGFR_EGFR_EGF_EGF_GRB2_GAB1_1act_integral_to_membrane_v1) and ( not (EGFR_EGFR_1ina_integral_to_membrane or EGFR_EGFR_EGF_EGF_GRB2_GAB1_1ina_integral_to_membrane))) blue _h_2434_74 ((EGFR_EGFR_1act_integral_to_membrane_v1 or EGFR_EGFR_EGF_EGF_GRB2_GAB1_1act_integral_to_membrane_v1) and ( not (EGFR_EGFR_1ina_integral_to_membrane or EGFR_EGFR_EGF_EGF_GRB2_GAB1_1ina_integral_to_membrane))) blue _h_2434_77 ((EGFR_EGFR_1act_integral_to_membrane_v1 or EGFR_EGFR_EGF_EGF_GRB2_GAB1_1act_integral_to_membrane_v1) and ( not (EGFR_EGFR_1ina_integral_to_membrane or EGFR_EGFR_EGF_EGF_GRB2_GAB1_1ina_integral_to_membrane))) grey blue _h_2434_71 ((EGFR_EGFR_1act_integral_to_membrane_v1 or EGFR_EGFR_EGF_EGF_GRB2_GAB1_1act_integral_to_membrane_v1) and ( not (EGFR_EGFR_1ina_integral_to_membrane or EGFR_EGFR_EGF_EGF_GRB2_GAB1_1ina_integral_to_membrane))) blue _h_2434_70 ((EGFR_EGFR_1act_integral_to_membrane_v1 or EGFR_EGFR_EGF_EGF_GRB2_GAB1_1act_integral_to_membrane_v1) and ( not (EGFR_EGFR_1ina_integral_to_membrane or EGFR_EGFR_EGF_EGF_GRB2_GAB1_1ina_integral_to_membrane))) blue _h_2434_73 ((EGFR_EGFR_1act_integral_to_membrane_v1 or EGFR_EGFR_EGF_EGF_GRB2_GAB1_1act_integral_to_membrane_v1) and ( not (EGFR_EGFR_1ina_integral_to_membrane or EGFR_EGFR_EGF_EGF_GRB2_GAB1_1ina_integral_to_membrane))) grey grey _h_3546 blue PGC1A_nucleus and YY1_nucleus _h_3545 blue GATA1_nucleus red grey red _h_3263_24 blue FGFR1c_FGF5_1act _h_1594 blue TRAIL_TRAILR1_DAP3_GTP_integral_to_membrane blue _h_3549 (( not (SLUG_nucleus or p53__tetramer__nucleus_v7)) and ((GCN5_L_ADA2B_TAF9_nucleus or SP1_3_nucleus) or p53__tetramer__nucleus_v10)) blue _h_3548 HB_EGF_EGFR_1act grey red grey _h_2538 blue ER_alpha_nucleus blue _h_1853 (E2F1 and ( not ((NFAT1_1O_7O_2s_1act_nucleus or NFAT4_1act_nucleus) or NFATc_1act_nucleus))) _h_3263_21 blue FGFR1c_FGF6_1act grey grey grey grey _h_3263_20 blue FGFR1b_FGF10_1act red grey grey grey red grey red red grey red grey blue _h_520 Antigen_IgE_Fc_epsilon_R1_LYN_SYK_v2 grey _h_2564 blue SHH_Np_Cholesterol_extracellular_region _h_2299 blue SKI_SIN3a_NCoR1_TIF1B_nucleus grey blue _h_1598 Akt1_1O_1O_1act_plasma_membrane blue _h_5869 STAT3__dimer___1act blue _h_5867 FGFR_FGF2_complex_N_cadherin blue _h_5864 E2F1_DP_nucleus_v4 _h_5862 blue KLF4 red grey blue _h_1036_63 Arf6_GTP_1act or Arf6_GTP_1act_plasma_membrane blue _h_1036_62 Arf6_GTP_1act or Arf6_GTP_1act_plasma_membrane blue _h_1036_61 Arf6_GTP_1act or Arf6_GTP_1act_plasma_membrane red blue _h_1036_67 Arf6_GTP_1act or Arf6_GTP_1act_plasma_membrane blue _h_1036_66 Arf6_GTP_1act or Arf6_GTP_1act_plasma_membrane red red blue _h_1036_69 Arf6_GTP_1act or Arf6_GTP_1act_plasma_membrane blue _h_1036_68 Arf6_GTP_1act or Arf6_GTP_1act_plasma_membrane grey _h_2312_2 blue SMAD2_3_SMAD4_nucleus_SMAD2_2O_1act_SMAD4 blue _h_3136 Plasmin_1act red grey red grey _h_528 blue TCR_CD3_MHC_II_CD4_1act_integral_to_membrane and not Gi_family_GTP_RGS1_1act_cytoplasm and (B7_family_CD28_1act_integral_to_membrane_v2 or GNB1_GNG2_1act_cytoplasm) grey red blue _h_3138 (E2F1_DP_nucleus_v4 and ( not p107_nucleus)) blue _h_3139 PKC_beta or PKC_delta or PKC_epsilon or PKC_isoenzymes red red grey _h_2693 blue Tie2 red red grey _h_2355_2 blue ARC105 _h_2355_1 blue ARC105 grey grey red red red red red grey red red red red blue _h_660_2 cortisol red grey red red grey _h_3250_6 blue SIK1_1O_1act_cytoplasm _h_4011_2 blue FGFR1b_FGF2_plasma_membrane grey grey grey red grey red grey grey red blue _h_6020_2 SMO_beta_Arrestin2_1act_clathrin_coat_of_coated_pit red grey grey red blue _h_5131_1 (((((BRAF_1act_plasma_membrane or RAF1_1O_1act_v1) or RAF1_1O_1act_v2) or RAF1_1act) or RAF1_2O_1act) or netrin_1_DCC_1act_integral_to_membrane) red grey red red grey red red red grey red blue _h_2553 JUN_ATF2_1act_nucleus red blue _h_2550 Src_1O_1act_cell_cell_junction red _h_2556 blue alpha4_beta1_Integrin_integral_to_membrane_v1 grey _h_2530 blue HDAC11_nucleus grey _h_2558 blue alpha4_beta1_Integrin_Fibronectin_integral_to_membrane red grey grey grey red grey blue _h_4249 VEGFR2_VEGFA__dimer__1act_plasma_membrane _h_4248 blue Tubulin_cytoplasm _h_4245 blue IL27RA _h_4244 blue FAK _h_4247 blue Ca2__v1 or Caspase_3_1act or Gelsolin _h_4246 blue SMAD3_SMAD4_1act_nucleus _h_4241 blue Rar_gamma1 and (TFIIH or p38_alpha_1O_1O_1act_v2) blue _h_4240 Fibronectin_v1 or PKC_alpha_1act grey _h_1426_3 blue Akt1_1O_1O_1act_plasma_membrane and MSP and YWHAG grey red grey grey _h_2532 blue PRX1 grey red grey red red red grey grey red blue _h_2434_72 ((EGFR_EGFR_1act_integral_to_membrane_v1 or EGFR_EGFR_EGF_EGF_GRB2_GAB1_1act_integral_to_membrane_v1) and ( not (EGFR_EGFR_1ina_integral_to_membrane or EGFR_EGFR_EGF_EGF_GRB2_GAB1_1ina_integral_to_membrane))) grey red blue _h_3547 HIF1A_ARNT_nucleus red grey red grey red grey grey red _h_5264 blue (GRB2_SOS1_plasma_membrane and GTP_v1) red grey blue _h_5260 CDC14B_nucleoplasm red blue _h_5262 mTORC2_1act blue _h_5263 HGS_endosome or LST2_endosome or TSG101 or Vps24 grey red blue _h_5269 not MYC_Max_nucleus_v4 grey _h_6074 blue Caspase_6_1act _h_6075 blue YWHAS red red grey blue _h_6072 IL2_IL2R_alpha_beta_gamma_JAK1_LCK_JAK3_STAM1_2_1act_integral_to_membrane _h_6073 blue Thy1 grey blue _h_3724 HES1_HES6_1act_nucleus grey blue _h_6078 Ca2__cytoplasm or Ca____cytoplasm or LPA_LPA1 or LPA_LPA2 _h_6079 blue Type_VII_Collagen_extracellular_region grey red _h_2895 blue Galectin3_cytoplasm grey grey red _h_3738 blue ErbB2_integral_to_membrane and betacellulin_extracellular_region blue _h_3739 ( not PRL_3) grey grey blue _h_3734 dNp73b__tetramer__nucleus _h_3735 blue SHC_cytoplasm blue _h_3736 IL12_IL12R_TYK2_JAK2_1act_integral_to_membrane or IL2_IL2R_1act_integral_to_membrane or p38_alpha_1O_1O_1act_v2 blue _h_2891 Citron_1act red red red blue _h_3733 PLK1_1O_1act_outer_kinetochore_of_condensed_chromosome red grey grey grey grey grey grey grey _h_1295 blue ((((BMP2_4__homodimer__extracellular_region and BMPR1A_1B__homodimer__integral_to_membrane) and BMPR2__homodimer__1act_integral_to_membrane) and CER1) and RGM_family) blue _h_1398 ((CBP_nucleus or p300_nucleus) or p53__tetramer__nucleus_v2) grey red blue _h_1394 PLEKHA7_cell_cell_junction blue _h_1395 HIF2A_ARNT_nucleus_v3 blue _h_1849_4 p38_alpha_1O_1O_1act_v2 blue _h_1390 Erk2_1O_1O_1act red red grey grey blue _h_3819 Antigen_IgE_Fc_epsilon_R1 or Ca___cytoplasm grey red grey blue _h_5671 IL18_IL18R_1act or STAT4__dimer__1act_nucleus_v2 blue _h_5670 (STAT3__dimer__active_1act_nucleus or cortisol_GR_alpha__monomer__nucleus) blue _h_5675 (Erk1_1O_1act_1O_nucleus or Erk2_1O_1O_1act_nucleus) red blue _h_5679 Lethal_Factor_cytoplasm grey red red grey red grey red red grey blue _h_514 alphav_beta3_Integrin_JAM_A blue _h_516 BRSK1_1O_1act_cytoplasm or BRSK2_1O_1act_cytoplasm or MARK2_1O_1act_cytoplasm blue _h_517 Ca2__v1 or LIS1_IQGAP1 blue _h_510 Gangliosides_and_protein_receptor__synaptotagmin_I_and_II__extracellular_region blue _h_512 Ephrin_A1_EPHA2_1act_integral_to_membrane grey red red grey red grey grey _h_5567_2 blue Axin1_GSK3_cytoplasm_GSK3beta_Axin1 _h_5567_1 blue WNT3A_LRP6_FZD5_DVL_1act_integral_to_membrane_v1 _h_5359 blue VCAM1_integral_to_membrane grey grey grey blue _h_1399 (JUN_JUN_FOS_JAB1_1act_nucleus_JAB1_FOS_JUN_2O_2O or JUN_JUN_FOS_JAB1_1act_nucleus_JUN_JAB1_JUN_2O_2O) grey red blue _h_1113 not E2F6_DP_nucleus _h_1136 blue JAM_B and JAM_C_homodimer red red red _h_6327 blue LIS1 grey blue _h_1440 dNp63a__tetramer__nucleus_v2 red grey blue _h_1117 (( not Gelsolin) and ((((BAD_4O_1act or BAX_1act) or BID) or Caspase_10_1act) or proNGF__dimer__p75_NTR__Sortilin_NRAGE_1act_integral_to_membrane)) red red _h_1114 blue (EGFR_EGFR_EGF_EGF_1act_integral_to_membrane_v1 or RET_GFRalpha1_GDNF_1act_integral_to_membrane) red grey _h_2274 blue JUNB_nucleus blue _h_3916 SGK1_1O_1O_1act_nucleus red grey grey grey grey blue _h_4811 PKA_1act blue _h_4812 RHOA_GTP_1act_plasma_membrane red grey red _h_4816 blue TRKB_1N_integral_to_membrane and not p75_NTR__1N_integral_to_membrane blue _h_4817 (AR_T_DHT_nucleus or HIP1) blue _h_4818 CDK2_Cyclin_E1 or mTORC1_1act grey red grey blue _h_5899_77 ErbB2_ErbB3_neuregulin_1_beta_1act_integral_to_membrane_v1 blue _h_5899_76 ErbB2_ErbB3_neuregulin_1_beta_1act_integral_to_membrane_v1 blue _h_5899_75 ErbB2_ErbB3_neuregulin_1_beta_1act_integral_to_membrane_v1 blue _h_5899_74 ErbB2_ErbB3_neuregulin_1_beta_1act_integral_to_membrane_v1 blue _h_5899_73 ErbB2_ErbB3_neuregulin_1_beta_1act_integral_to_membrane_v1 blue _h_5899_72 ErbB2_ErbB3_neuregulin_1_beta_1act_integral_to_membrane_v1 red red red blue _h_5899_79 ErbB2_ErbB3_neuregulin_1_beta_1act_integral_to_membrane_v1 grey blue _h_601 PKC_zeta_1act_plasma_membrane or RHOA_GTP_1act grey red red grey blue _h_3910 Ca2__cytoplasm or DAG_v1 grey grey _h_4975 blue LAT_GRAP2_SLP76_VAV1_1act _h_3263_53 blue FGFR1b_FGF10_1act grey grey red blue _h_2279 B_cell_antigen_BCR_complex_LYN_SYK_BLNK red blue _h_3970_3 ETA_receptor_Endothelin_1_Gs_GTP_1act_integral_to_membrane or PKC_epsilon_1act_cytoplasm red red grey grey red _h_5964_1 blue E2F4_cytoplasm and p107 grey grey grey red red blue _h_1968 (AR_T_DHT_nucleus or ASC2) grey grey grey blue _h_6128 SMAD3_SMAD4_JUN_FOS_1act_nucleus grey blue _h_4973 Erk2_1O_1O_1act red _h_6354 blue SMAD2_SMAD2_SMAD4_1act_nucleus_v3 grey blue _h_4800 RAS_family_GTP_1act_plasma_membrane_H_RAS_isoform_1_GTP_v1 or RAS_family_GTP_1act_plasma_membrane_N_RAS_GTP_v1 red red grey blue _h_4985 CaMK_II_delta_B or TGFB_TGFBR2_TGFBR1_1act_integral_to_membrane _h_1804 blue IFN_gamma_IFN_gammaR_JAK1_JAK1_JAK2_JAK2_1act grey red _h_38 blue not ARF1_GTP_GGA3_ARF_GAP1_1act_Golgi_to_ER_transport_vesicle_membrane and (ARF_GAP1_1act or ASAP1_1act_plasma_membrane or GIT_1_2_1act_plasma_membrane or KDEL_ARF_GAP1_1act) grey grey _h_4774 blue RAC1_GTP_1act_plasma_membrane _h_34 blue Caspase_10 and c_FLIPS blue _h_35 Akt1_1O_1O_1act_plasma_membrane _h_36 blue VEGFR3_plasma_membrane blue _h_37 CK2 or MAPK_14 grey _h_4777 blue PGK_cGMP_1act and TAB1 grey grey blue _h_3091 MYC_Max_nucleus_v2 grey _h_3093 blue CBL red blue _h_3095 TNF_alpha_TNFR1A grey grey grey red red red _h_3907 blue (RAC1_GDP_1ina_v1 and ( not Ephrin_B1_EPHB1_2_1act_integral_to_membrane_v1)) blue _h_1127 ( not E2F1) grey red blue _h_4301 (AR_T_DHT_nucleus or RSK2) blue _h_2733 RPE65_3S_plasma_membrane red _h_4772 blue Telomerase red _h_3905 blue Gelsolin_PI_3_4_5_P3 red blue _h_5079 ROCK2_1act or ROCK_1act blue _h_5078 proBDNF__dimer__p75_NTR__Sortilin_1act_integral_to_membrane or proNGF__dimer__p75_NTR__Sortilin_1act_integral_to_membrane blue _h_3904 ((((((((((EPO_EPOR__dimer__LYN or ETB_receptor_Endothelin_1_Gq_GTP_PLC_beta_1act_integral_to_membrane_ETB_ET1_PLC_beta3_Gq_family_GTP_v1) or ETB_receptor_Endothelin_1_Gq_GTP_PLC_beta_1act_integral_to_membrane_ETB_ET1_PLC_beta_2_Gq_family_GTP_v1) or IL4_IL4R_JAK1_IL2R_gamma_JAK3_1act_integral_to_membrane) or MEK1_2O_1act_cytoplasm) or MEKK1_1act) or MKK3_1O_1O_1act) or MKK4_1O_1O_1act_cytoplasm) or MKK6_1O_1O_1act) or RIP_MEKK3_1act) or S1P_S1P2_Gi) blue _h_4528_2 Fyn_1O_1act or LYN_1act_1O or Lck_1O_1act or RAL_GTP_1act or Src_1act_1O red grey blue _h_5075 ATF2_2O_1act_nucleus _h_5074 blue FAK_GRAF_1act_focal_adhesion blue _h_5077 p38_alpha_1O_1O_1act_v2 or p38_beta_1O_1O_1act blue _h_5076 p53__tetramer__nucleus_v2 _h_1949 blue RPA_ATR_ATRIP_RAD17_RFC2_5_9_1_1_TopBP1_1act_nucleus _h_6381_4 blue ((((AP2B2 and Caveolin_1) and PML_SARA_SMAD2_3_early_endosome) and TGFB_TGFBR2_TGFBR1_1act_integral_to_membrane) and ( not FKBP12)) red grey red blue _h_1941 not Ca2__cytoplasm and (CK1_alpha or GSK3beta or PRKACA or p38_alpha_1O_1O_1act_v2) blue _h_1940 IL23_IL23R_JAK2_TYK2_1act_integral_to_membrane grey _h_1942 blue Fibronectin_v1 and Tie2_Ang1_1act blue _h_1945 Caspase_1__tetramer__1act red blue _h_5941 E2F3_DP_RYBP_YY1_nucleus blue _h_4778 RAC1_GTP_1act_cell_cell_junction _h_3899 blue NRP2 and VEGFC__dimer__extracellular_region _h_4838_4 blue YWHAS_nucleus red grey _h_817_1 blue p38_beta_1O_1O_1act grey _h_3893 blue Syndecan_3 red blue _h_3894 Gamma_Secretase_1act grey grey red blue _h_2769 Erk2_1O_1O_1act _h_5381 blue XLF__dimer_ blue _h_5380 PPP2CA or PPP2CB or TGFB_TGFBR2_TGFBR1_PPP2R2A_1act_integral_to_membrane _h_5387 blue Thrombospondin and alphaIIb_beta3_Integrin_integral_to_membrane _h_6381_2 blue ((((Caveolin_1 and PML_SARA_SMAD2_3_early_endosome) and SMAD7_SMURF1_2_nucleus_Smad7_SMURF1) and TGFB_TGFBR2_TGFBR1_1act_integral_to_membrane) and ( not FKBP12)) blue _h_5384 TAp73a__tetramer__nucleus_v3 blue _h_2762 IP3 blue _h_5388 Serine_Threonine_Kinases blue _h_4702_1 Akt1_1O_1O_1act blue _h_2765 ABI1_Sra1_Nap1_cell_cell_junction _h_2766 blue PKC_alpha_1O_1act_plasma_membrane red red red blue _h_6295 ((((((((DHT_plasma_membrane or Fes_1act_1O_cytoplasm) or IL3_IL3RA_CSF2RB__dodecamer__YWHAZ_SHC_1act_integral_to_membrane) or IL5_IL5RA_CSF2RB__hexamer__JAK2_JAK2_1act_v2) or Tie2_Ang1_1act) or Tie2_Ang1_Shc_1act) or Tie2_Ang2) or VEGFR1_homodimer_PLGF_homodimer_1act_plasma_membrane) or testosterone_plasma_membrane) blue _h_1496 (JUN_FOS_1act_nucleus_v1 and ( not cortisol_GR_alpha__monomer__nucleus)) red red blue _h_830_6 PIN1_1act or PP2A_1act_v1 blue _h_1499 not MYC_Max_nucleus_v4 red blue _h_1275 FOXO1_SIRT1_1act_nucleus blue _h_1742_2 (Arf6_GTP_1act or SCAMP2) blue _h_1742_1 (Arf6_GTP_1act or SCAMP2) blue _h_4696_3 (DHT_plasma_membrane or testosterone_plasma_membrane) _h_5863 blue LRP1 red red blue _h_5860 Src_1act_1O grey grey red grey grey grey grey _h_2268_4 blue NCK2 _h_2268_2 blue FAK_Src_Yes_Fyn_p130_CAS_1act_focal_adhesion_Fyn_1O_1act_p130Cas_1O_FAK_6O_1act _h_2268_3 blue NCK1 grey blue _h_2457 E_cadherin_Ca2__beta_catenin_alpha_catenin_p120_catenin_cell_cell_junction_v1 blue _h_1036_60 Arf6_GTP_1act or Arf6_GTP_1act_plasma_membrane grey red grey red _h_2673 blue BoNT_G_Light_Chain_1act_cytoplasm grey grey red red _h_1017 blue FGF2_extracellular_region and FGFR1b blue _h_1036_65 Arf6_GTP_1act or Arf6_GTP_1act_plasma_membrane grey _h_4381 blue (C3G_1act_cell_cell_junction and GTP_v1) _h_4382 blue GRB2_SOS1_v2 blue _h_1036_64 Arf6_GTP_1act or Arf6_GTP_1act_plasma_membrane _h_4384 blue PLK1_1O_1act_kinetochore _h_4385 blue G13_GTP_1act_plasma_membrane_v2 _h_4386 blue ICAM1 _h_4387 blue JNK blue _h_4915 APC_C_1act grey grey _h_1237 blue Laminin_2_basement_membrane grey red red blue _h_1233 Fra1_JUN_1act_nucleus red _h_1339 blue Rap1 and TRF2 red red red red _h_1239 blue GLI2A_1act_nucleus grey grey blue _h_4033 P39_CDK5 or p35_CDK5 red blue _h_4031 (AR_T_DHT_nucleus and ( not SRY)) _h_4036 blue ARF1_GDP_plasma_membrane and Membrin blue _h_4037 p53__tetramer__nucleus_v2 red blue _h_4035 MYC_Max_TRRAP_GCN5_STAF65G_SPT3_TAF9_TAF10_TAF12_core_Mediator_nucleus grey blue _h_4038 beta_catenin_MED12_1act_nucleus _h_4039 blue IL4_extracellular_region red red grey blue _h_5051_56 (RAS_family_GTP_1act_plasma_membrane_H_RAS_isoform_1_GTP_v1 or RAS_family_GTP_1act_plasma_membrane_N_RAS_GTP_v1) red red grey _h_3135 blue Tie2_Ang1_1act red red _h_3132 blue TEC and p62DOK blue _h_4528_1 Fyn_1O_1act or LYN_1act_1O or Lck_1O_1act or RAL_GTP_1act or Src_1act_1O red blue _h_4608_2 (Arf6_GTP_1act or RALA_GTP_1act) blue _h_4608_1 (Arf6_GTP_1act or RALA_GTP_1act) red grey red grey red blue _h_6496 dNp63a__tetramer__nucleus_v2 grey red grey red red red red blue _h_3528 E2_ERA__dimer__1act_nucleus grey red _h_5227 blue RIP and TRADD red red _h_2674 blue E2_nucleus blue _h_1793 Src_1act_1O_cell_leading_edge blue _h_1034 SRF__dimer__Myocardin_1act_nucleus and not ELK1_SRF_1act_nucleus_v2 grey grey red red grey grey grey grey blue _h_893 Fyn_1O_1act blue _h_892 BRSK1_1O_1act_cytoplasm or BRSK2_1O_1act_cytoplasm or MARK2_1O_1act_cytoplasm grey _h_899 blue (Cyclin_A_E1_CDK1_2_1act_Cyclin_A_CDK2 or Cyclin_A_E1_CDK1_2_1act_Cyclin_E1_CDK2) blue _h_898 KLF8_1act_nucleus blue _h_2434_57 ((EGFR_EGFR_1act_integral_to_membrane_v1 or EGFR_EGFR_EGF_EGF_GRB2_GAB1_1act_integral_to_membrane_v1) and ( not (EGFR_EGFR_1ina_integral_to_membrane or EGFR_EGFR_EGF_EGF_GRB2_GAB1_1ina_integral_to_membrane))) grey blue _h_2434_55 ((EGFR_EGFR_1act_integral_to_membrane_v1 or EGFR_EGFR_EGF_EGF_GRB2_GAB1_1act_integral_to_membrane_v1) and ( not (EGFR_EGFR_1ina_integral_to_membrane or EGFR_EGFR_EGF_EGF_GRB2_GAB1_1ina_integral_to_membrane))) blue _h_2434_54 ((EGFR_EGFR_1act_integral_to_membrane_v1 or EGFR_EGFR_EGF_EGF_GRB2_GAB1_1act_integral_to_membrane_v1) and ( not (EGFR_EGFR_1ina_integral_to_membrane or EGFR_EGFR_EGF_EGF_GRB2_GAB1_1ina_integral_to_membrane))) grey blue _h_2434_52 ((EGFR_EGFR_1act_integral_to_membrane_v1 or EGFR_EGFR_EGF_EGF_GRB2_GAB1_1act_integral_to_membrane_v1) and ( not (EGFR_EGFR_1ina_integral_to_membrane or EGFR_EGFR_EGF_EGF_GRB2_GAB1_1ina_integral_to_membrane))) blue _h_2434_51 ((EGFR_EGFR_1act_integral_to_membrane_v1 or EGFR_EGFR_EGF_EGF_GRB2_GAB1_1act_integral_to_membrane_v1) and ( not (EGFR_EGFR_1ina_integral_to_membrane or EGFR_EGFR_EGF_EGF_GRB2_GAB1_1ina_integral_to_membrane))) red red blue _h_2434_58 ((EGFR_EGFR_1act_integral_to_membrane_v1 or EGFR_EGFR_EGF_EGF_GRB2_GAB1_1act_integral_to_membrane_v1) and ( not (EGFR_EGFR_1ina_integral_to_membrane or EGFR_EGFR_EGF_EGF_GRB2_GAB1_1ina_integral_to_membrane))) _h_1426_1 blue Akt1_1O_1O_1act_plasma_membrane and Ron and YWHAS blue _h_938_5 PIN1_1act or PP2A_1act_v1 blue _h_3563 not Myb_GATA1_nucleus and (CBP or GATA1_nucleus or p300) grey blue _h_3565 Myb_nucleus _h_3854 blue alpha6_beta1_Integrin_integral_to_membrane grey blue _h_3569 LKB1_ER_alpha_nucleus _h_3568 blue (GTP_v1 and (((((VEGFR2__dimer__VEGFA__dimer__Fyn_NCK1_2_PAK2_1act_integral_to_membrane_Fyn_1O_1act_NCK2_PAK2_1O_VEGFA189_VEGFR2_9O or VEGFR2__dimer__VEGFA__dimer__Fyn_NCK1_2_PAK2_1act_integral_to_membrane_Fyn_1O_1act_PAK2_1O_NCK1_VEGFA189_VEGFR2_9O) or Yes_1act) or alphaPIX_1act) or betaPIX_1O_1act) or netrin_1_DCC_1act_integral_to_membrane)) grey red blue _h_5740 MDM2 red grey red grey blue _h_5745 HIF1A_ARNT_nucleus red grey grey red grey grey red blue _h_5303 PLK1_1O_1act red grey grey red grey grey _h_4611 blue HDAC6_cytoplasm grey red red blue _h_80 alpha4_beta1_Integrin_VCAM1_Paxillin_integral_to_membrane _h_5808 blue alpha4_beta1_Integrin_integral_to_membrane_v1 _h_5809 blue IL2_IL2R_alpha_beta_gamma_JAK1_LCK_JAK3_SHC_GRB2_SOS1_GAB2_SHP2_1act_integral_to_membrane and RHOA_GTP_1act grey grey grey blue _h_5801 TAp63g__tetramer__1act_nucleus_v2 grey blue _h_5805 TAp73a__tetramer__nucleus_v3 blue _h_5806 ERK5_1O_1O_1act_nucleus blue _h_5807 NF_Kappa_B1_1act red blue _h_6132 dNp63a__tetramer__nucleus_v2 _h_2257 blue CaM_Ca2__Calcineurin_A_alpha_beta_B1_1act_v2 grey blue _h_2390 (TAp73a__tetramer__nucleus_v3 and ( not RelA)) grey blue _h_3150 Fra2_JUN_1act_nucleus_v2 blue _h_3151 Akt1_1O_1act_1O_1O_plasma_membrane blue _h_3152 (STAT5A__dimer__active_1act_nucleus_v2 or Tie2_Ang2) blue _h_3153 (AR_T_DHT_nucleus and ( not LATS2)) _h_3154 blue YY1_nucleus red blue _h_3156 not Myb_nucleus _h_3157 blue YY1_1act_1N_nucleus blue _h_3159 Cyclin_B1_CDK1_1act_v1 or PLK1_1O_1act grey grey blue _h_592 MYC_Max_TRRAP_TIP60_TIP49A_TIP49B_BAF53_nucleus blue _h_3837_2 ((PKC_epsilon_Par3_Par6_CDC42_GTP or Src_1act) or Yes_1act) blue _h_3837_1 ((PKC_epsilon_Par3_Par6_CDC42_GTP or Src_1act) or Yes_1act) grey red grey grey red red red red red _h_6134 blue Estrogen_receptor_alpha grey red _h_5898 blue CD81_v1 red grey grey red grey red blue _h_4114 ((Erk1_1O_1act_1O_cytoplasm or Erk2_1O_1O_1act_cytoplasm) or RHOA_GTP_1act) grey grey red _h_2084_6 blue YWHAQ grey blue _h_660_1 cortisol red grey grey grey red blue _h_807_53 FASLG_FAS__trimer__Src_Syk_1act_integral_to_membrane or TRAIL__trimer__extracellular_region red grey grey grey red blue _h_426 HIF1A_ARNT_nucleus or SP1 grey red blue _h_935 (JUN_FOS_TRIP6_1act_nucleus and ( not JUN_FOS_GR_TRIP6_cortisol_GR_alpha__dimer__1act_nucleus)) blue _h_2579 TAp73a__tetramer__nucleus_v3 blue _h_2578 GSK3beta_cytoplasm blue _h_420 PDGF_PDGFRA_1act _h_2577 blue CDC25C_1O grey _h_26 blue GTP_v1 and Gq_family_GDP_1ina blue _h_2570 PAK1 blue _h_2573 GNB1_GNG2_1act blue _h_933 Erk2_1O_1O_1act _h_5451_1 blue WNT3A_LRP6_FZD5_DVL_1act_integral_to_membrane_v2 red _h_5451_2 blue Axin1_GSK3_cytoplasm_GSK3beta_Axin1 blue _h_422 SRF_dimer__MAL_dimer__1act_nucleus red grey grey grey red blue _h_204 E_cadherin_Ca2__beta_catenin_alpha_catenin_p120_catenin_cell_cell_junction_v1 red grey blue _h_5173_2 cortisol red grey grey grey grey grey grey blue _h_875 (Fra1_JUN_1act_nucleus and ( not Fra1_FIAT_1act_nucleus)) grey red _h_2166_4 blue PDGF_BB_PDGFRB__dimer__RasGAP_1act_integral_to_membrane _h_2166_3 blue Src _h_2166_2 blue PDGF_BB_PDGFRB__dimer__RasGAP_1act_integral_to_membrane _h_2166_1 blue Fyn grey blue _h_1036_7 Arf6_GTP_1act or Arf6_GTP_1act_plasma_membrane red red _h_2990_1 blue Kremen_2_integral_to_membrane _h_2990_2 blue Kremen_1_integral_to_membrane red red grey blue _h_6194 RAB7_GTP_1act_perinuclear_region_of_cytoplasm red grey red blue _h_1036_3 Arf6_GTP_1act or Arf6_GTP_1act_plasma_membrane grey grey grey blue _h_2516 E_cadherin_Ca2__beta_catenin_alpha_catenin_p120_catenin_cell_cell_junction_v1 _h_2613 blue ROCK2_1act or ROCK_1act red _h_1816 blue IGF_1R_heterotetramer_IGF1_IRS1_caveola_v2 grey blue _h_21 TCR_CD3_MHC_II_CD4_LCK_ZAP_70_1act_integral_to_membrane blue _h_209 SRF_dimer__MAL_dimer__1act_nucleus red grey blue _h_1814 E2_ERA__dimer__1act_nucleus red red grey blue _h_1649 PDK1_1act or PI3K_GAB1_1act_plasma_membrane or PI_3_4_5_P3_plasma_membrane grey grey grey _h_25 blue (CBL_CRKL_C3G_1act and RAP1_GDP_1ina_integral_to_membrane) blue _h_5248 E2F2_DP_RYBP_YY1_nucleus grey _h_5246 blue SHC_cytoplasm _h_5247 blue P39 _h_3263_78 blue FGFR1b_FGF2_1act _h_24 blue SMO_beta_Arrestin2_1act_clathrin_coat_of_coated_pit or hFu grey blue _h_5243 TAp63b__tetramer__1act_nucleus_v2 _h_5241 blue RelA grey grey blue _h_6058 Sprouty2 grey blue _h_1005 Gangliosides_and_protein_receptor__synaptotagmin_I_and_II__extracellular_region _h_1006 blue PI3K _h_6055 blue GATA1_nucleus _h_1000 blue HES1_nucleus and RB1_nucleus blue _h_1001 Akt1_1O_1O_1act_plasma_membrane _h_1002 blue PIM1_1act_nucleus and p100_nucleus _h_1003 blue YY1_LSF_nucleus blue _h_3716 (HZF_nucleus or p53__tetramer__nucleus_v2) red grey _h_3713 blue Syndecan_4 grey blue _h_3711 STAT4__dimer__1act_nucleus_v2 _h_3263_79 blue FGFR1c_FGF2_1act red blue _h_2413 ((GCN5_L_ADA2B_TAF9_nucleus or p53_Cbp_p300_CARM1_PRMT1__tetramer__nucleus_PRMT1_CARM1_CBP_p53) or p53_Cbp_p300_CARM1_PRMT1__tetramer__nucleus_PRMT1_CARM1_p300_p53) blue _h_3718 PPP2R1A_PPP2CA_PPP2R2A_1act _h_3719 blue SMAD8A_2O_1act_cytoplasm _h_3834 blue Ephrin_A1_EPHA2_1act_integral_to_membrane _h_1819 blue Ang1 grey _h_1818 blue PAK1 red grey grey grey grey grey grey blue _h_4703 Ca2__cytoplasm grey grey blue _h_3224_1 MKK4_1O_1O_1act blue _h_3224_2 MKK4_1O_1O_1act grey red grey blue _h_273 SCF_KIT_1act red blue _h_4167_1 EPO_EPOR__dimer__JAK2 or EPO_EPOR__dimer__LYN red blue _h_2944_24 not E_cadherin_cytoplasm and (MAPK_14 or p120ctn) grey blue _h_3207 VEGFR1_2__dimer__VEGFA__dimer__1act_integral_to_membrane or VEGFR2__dimer__VEGFA__dimer__1act_integral_to_membrane_v1 _h_5659 blue BMP2_4_BMPR2_BMPR1A_1B_RGM_1act_integral_to_membrane blue _h_5658 Sema3e_Plexin_D1_integral_to_membrane grey blue _h_3200 ( not JUN_FOS_1act_nucleus_v4) blue _h_2618 HPV_16_E6_E6AP grey blue _h_5651 Plasmin_1act _h_5650 blue JUN_2O_2O_nucleus red _h_5652 blue CBP grey blue _h_6020_3 SMO_beta_Arrestin2_1act_clathrin_coat_of_coated_pit red grey grey grey grey blue _h_4122 E_cadherin_Ca2__beta_catenin_gamma_catenin_alpha_catenin_p120_catenin_cell_cell_junction_v2 or LPP_1act_cell_cell_junction or zyxin_1act_cell_cell_junction grey _h_5086 blue JUN_nucleus grey grey grey _h_3659 blue COL18A1_extracellular_region grey grey _h_3209 blue alpha5_beta1_Integrin_1act_integral_to_membrane red red grey red grey grey blue _h_2944_29 not E_cadherin_cytoplasm and (MAPK_14 or p120ctn) grey grey blue _h_688 (( not E2F6_DP_nucleus) and (E2F1_DP_nucleus_v2 or SP1)) _h_790 blue TFPI grey blue _h_796 Src_1act_1O grey blue _h_794 ILK_1act_1p blue _h_5690 Exportin_1 red _h_799 blue uPA_uPAR_alphav_beta5_Integrin_Vitronectin_1act_integral_to_membrane grey _h_189 blue SHARP_RBPJ_CtIP_CtBP_LSD1_nucleus grey grey blue _h_4128 ((JUN_FOSNFAT1_c_4_1act_nucleus_c_Jun_2O_NFAT1_1O_7O_2s_1act_nucleus_FOS_1O_1O or JUN_FOSNFAT1_c_4_1act_nucleus_c_Jun_2O_NFAT4_1act_nucleus_FOS_1O_1O) or JUN_FOSNFAT1_c_4_1act_nucleus_c_Jun_2O_NFATc_1act_nucleus_FOS_1O_1O) _h_4129 blue ((GTP_v1 and ( not (RAC1_GTP_1act_plasma_membrane or Tiam1_1act))) and ((((((((((((ARAP3_RAP1A_GTP_1act or Arf6_GTP_1act) or Ca2__extracellular_region) or DVL_DAAM1_1act_v1_DVL1_1act_DAAM1_1act) or DVL_DAAM1_1act_v1_DVL2_1act_DAAM1_1act) or DVL_DAAM1_1act_v1_DVL3_1act_DAAM1_1act) or HMGB1_TLR4_MD2__dimer__1act_integral_to_membrane) or IL2_IL2R_alpha_beta_gamma_JAK1_LCK_JAK3_1act_integral_to_membrane) or LPA_LPA2_MAGI_3) or PI3K_1act_plasma_membrane_v2) or VEGFR2__dimer__VEGFA__dimer__Hsp90_alphav_beta3_Integrin_Vitronectin_1act_integral_to_membrane) or netrin_1_UNC5A_1act_integral_to_membrane) or p115RhoGEF_1act)) red red grey grey grey grey grey red blue _h_1376 Syndecan_2 blue _h_4008 (CK1_alpha or CK1_epsilon) and not (WNT3A_FZD5_LRP6_1act_integral_to_membrane_v1 or WNT3A_LRP6_FZD5_DVL_1act_integral_to_membrane_v3 or WNT3A_LRP6_FZD5_DVL_Axin1_GSK3_1act_signalosome_v1) red _h_4111 blue ((GTP_v1 and ( not (NME1 or RHOGDI))) and ((((((((((((((((((((((((AND_34_1act or ARHGEF9_1act) or ASEF2_APC_1act) or BDNF__dimer__TRKB_1act_integral_to_membrane_v1) or CDC42_GTP_DOCK11_plasma_membrane) or DBL_1act) or DBS_1act) or DBS_1act_1O) or DOCK10_1act) or DOCK11_1act) or DOCK6_1act) or DOCK9_1act) or Ephexin_1act) or FGD1_1act) or FRG_1act_cell_cell_junction) or GEFT_1act) or Intersectin2_1act) or Intersectin_1act) or PI_4_5_P2_plasma_membrane) or PLCgamma1_betaPIX_GIT1_1act) or Tuba_1act_cell_cell_junction) or VAV2_1act_plasma_membrane) or Vav3_1act_plasma_membrane) or alphaPIX_1act) or betaPIX_1act)) blue _h_5434 Ephrin_B1_EPHB1_2_NCK1_1act_integral_to_membrane grey _h_4839 blue 14_3_3_E grey red grey grey _h_4833 blue CXCL10_extracellular_region and CXCR3_GNAI2_GDP_G_beta_gamma_integral_to_membrane and GTP_v1 grey _h_4831 blue (GTP_v1 and ((((Ca2__v1 or CalDAG_GEFIII_1act) or DAG_v2) or PLCepsilon) or RASGRP1_1act_Golgi_apparatus)) blue _h_4836 REF1 grey blue _h_4834 not CRBP1 and (PI_3_4_5_P3_plasma_membrane or RAR_alpha or RELN_VLDLR_DAB1_P13K or Rar_gamma1) _h_4523 blue Insulin_Receptor_Insulin_IRS1 grey grey grey grey grey blue _h_5048 PI3K_1act_plasma_membrane_v2 or PI_3_4_5_P3_plasma_membrane grey grey _h_598 blue VEGFR3_plasma_membrane grey grey blue _h_136 ((E2F1_DP_nucleus_v2 or SP1) and ( not (E2F4_DP2_p107_p130_HDAC1_nucleus_HDAC1_DP2_E2F4_p130 or E2F4_DP2_p107_p130_HDAC1_nucleus_HDAC1_DP2_p107_E2F4))) blue _h_137 GLI2A_1act_nucleus grey blue _h_135 (( not PTP1B_3O_1act_plasma_membrane) and (((((((((((((((((((((((((Antigen_IgE_Fc_epsilon_R1_LYN_SYK_v2 or CDC42_GTP_1act) or HGF_dimer__MET_dimer__GAB1_1act_integral_to_membrane_v2) or HRAS_GTP_1act_plasma_membrane) or HRAS_GTP_1act_v1) or IFN_gamma_IFN_gammaR_JAK1_JAK1_JAK2_JAK2_1act) or IGF_1R_heterotetramer_IGF1_IRS1_caveola_v2) or IRS2_1O_1act) or Insulin_Receptor_Insulin_1act) or Insulin_Receptor_Insulin_IRS1) or Insulin_Receptor_Insulin_IRS3) or PDGF_PDGFRA_1act) or RAC1_GTP_1act_v1) or RET51_GFRalpha1_GDNF_IRS1) or RET51_GFRalpha1_GDNF_SHC_GAB1_Grb2) or RET51_GFRalpha1_GDNF_v2) or RET9_GFRalpha1_GDNF_IRS1) or RET9_GFRalpha1_GDNF_SHC_GAB1_Grb2) or RET9_GFRalpha1_GDNF_Shank3_Grb2) or RHOA_GTP_1act) or SHC_GRB2_SOS1_1act_plasma_membrane) or VAV1_1act_1O) or VEGFR3_VEGFC_D_1act_plasma_membrane) or alpha6_beta4_Integrin_Laminin_hemidesmosome) or alphav_beta3_Integrin_JAM_A) or p70S6K_1act_cytoplasm)) _h_132 blue (p130Cas_1O and ( not PTP1B_p130_Cas)) blue _h_133 Alpha_Synuclein_DAT_plasma_membrane blue _h_130 not IL2_extracellular_region blue _h_131 EGFR_EGFR_EGF_EGF_1act_integral_to_membrane_v1 _h_4127 blue PER1_cytoplasm red _h_138 blue CD9 grey _h_6272 blue Gab1_cytoplasm and SHP2 and VEGFR2__dimer__VEGFA__dimer__1act_integral_to_membrane_v1 and eNOS_plasma_membrane blue _h_3994_4 GNB1_GNG2_1act_cytoplasm _h_1500 blue Caspase_3_1act _h_5040 blue FGFR1b and not ATP grey red blue _h_1503 HIF1A_ARNT_nucleus blue _h_3994_2 GNB1_GNG2_1act_cytoplasm grey _h_3263_77 blue FGFR1c_FGF6_1act blue _h_5042 E4ICDs_CYT2_1act_4O_nucleus red blue _h_1504 E2F3_DP_TFE3_nucleus grey grey grey red grey grey red grey red _h_1609 blue EGFR_EGFR_EGF_EGF_1act_endosome_v2 red grey red _h_2557 blue Ephrin_A5_integral_to_membrane red grey grey red red _h_1829 blue RIP and TRAF2 and sTNF_alpha_TNFR1A_TRADD_1act_integral_to_membrane and not CYLD blue _h_52 not Ca2__v1 blue _h_1827 STAT5__dimer__active_1act or cortisol_GR_alpha__monomer__nucleus grey blue _h_2554 (ETS1_nucleus or JUN_FOS_1act_nucleus_v4) blue _h_1822 Plasmin_1act blue _h_57 FOXO4_nucleus blue _h_1820 FGFR_FGF2_complex and not PI3K_1act_v2 _h_1821 blue alpha9_beta1_Integrin_integral_to_membrane blue _h_1602 not (STAT5A_B__dimer__1act_nucleus or STAT5A__dimer__active_1act_nucleus_v2 or STAT5B__dimer__1act_nucleus) grey blue _h_1603 LEF1_beta_catenin_1act_nucleus_v1 grey blue _h_5013 dNp63a__tetramer__nucleus_v2 _h_5012 blue RhoA_GDP_1ina _h_2894_14 blue FOXO1_1O_1ina_2O_nucleus blue _h_1977 Aurora_A blue _h_5017 not GSK3beta_1ina_1O_cytoplasm blue _h_5016 RAS_family_GTP_1act_plasma_membrane_H_RAS_isoform_1_GTP_v1 or RAS_family_GTP_1act_plasma_membrane_N_RAS_GTP_v1 _h_2290 blue HIV_1_Tat_1N_nucleus red grey blue _h_5018 HIF1A_ARNT_nucleus grey blue _h_2295 Myb_nucleus _h_2296 blue Caspase_3_1act _h_1607 blue SHH_Np_Cholesterol_extracellular_region _h_1923 blue IKK_beta blue _h_1922 not MYC_Max_nucleus_v4 _h_1921 blue SHIP_cytoplasm blue _h_205 TAp63b__tetramer__1act_nucleus_v1 red _h_1925 blue JUND_1act_nucleus blue _h_1929 not MYC_Max_MIZ_1_nucleus blue _h_1605 HIF1A_ARNT_nucleus or SP1_3_nucleus red blue _h_2875 STAT6__dimer__1act_nucleus_v1 _h_2894_17 blue YWHAB_nucleus _h_201_1 blue YWHAG red blue _h_1218 TAp63b__tetramer__1act_nucleus_v1 red blue _h_2877 JUN_FOS_RACO_1_1act_nucleus blue _h_766_2 BRAF_1O_1act_cytoplasm or IL2_IL2R_alpha_beta_gamma_JAK1_LCK_JAK3_SHC_GAB2_GRB2_SOS1_SHP2_PI3K_1act_integral_to_membrane or RAF1_1O_1O_1act_cytoplasm grey red grey _h_2878 blue NT3__dimer__extracellular_region and not p75_NTR__1N_integral_to_membrane red grey _h_2477 blue Tie2 _h_2750 blue (GTP_v1 and (((((((EGF_EGFR_dimer_SHC_GRB2_SOS1_1act_integral_to_membrane or PKC_beta_1act_plasma_membrane) or PKC_delta_1act_plasma_membrane) or PKC_epsilon_1act_plasma_membrane) or PKC_isoenzymes_1act_plasma_membrane) or PKC_theta_1act_plasma_membrane) or PRKCG_1act_plasma_membrane) or PRKCH_1act_plasma_membrane)) grey grey grey grey blue _h_4998 TCR_CD3_MHC_I_CD8_LCK_ZAP_70_1act_integral_to_membrane red red red grey grey grey grey grey red grey _h_4806_2 blue Gi_family grey red grey _h_5554 blue phospho_opsin_phosphatase _h_5555 blue GRB2 and SOS1_cytoplasm _h_2471 blue SHP2 blue _h_3340 RDH5 _h_5552 blue ILK grey grey grey _h_5550 blue E_cad_CTF2_p120_catenin_nucleus grey grey grey grey grey red red red blue _h_5249 SDF1_CXCR4_JAK2_1act_integral_to_membrane grey red red red blue _h_891_2 DUSP8 grey grey red grey blue _h_891_1 DUSP8 grey blue _h_2035 not (SIRT1_p300_nucleus or p300_2N_1act_nucleus) _h_2036 blue RB1_1ina_1p_nucleus and RB1_nucleus _h_5968 blue NF_kappa_B1_p50_RelA_1act_nucleus _h_2030 blue GPC1_plasma_membrane _h_2031 blue NCK2 and (RELN_LRP8 or RELN_VLDLR) blue _h_2744 SPHK1_1act_plasma_membrane blue _h_2033 Caspase_3__tetramer__1act blue _h_2748 PTP1B blue _h_5559 Cenexin_1_centrosome red blue _h_2039 JUN_ATF2_1act_nucleus grey grey _h_1211 blue PLD1_1act or PLD2_1act or PLD_1act_caveola grey _h_1212 blue LRP5_integral_to_membrane and WNT7B_extracellular_region grey blue _h_1217 dNp63a__tetramer__nucleus_v2 blue _h_1216 HIF1A_ARNT_nucleus _h_5747_3 blue JUN_2O_2O_nucleus blue _h_2777 Caspase_1__tetramer__1act _h_5747_1 blue JUN_nucleus blue _h_6278 proNGF__dimer__p75_NTR__Sortilin_1act_integral_to_membrane _h_2776 blue RACK1 grey grey red _h_5962 blue PLCgamma1_1act_cell_cell_junction _h_4242 blue (GTP_v1 and (HGF_dimer__MET_dimer__1act_integral_to_membrane_v1 or VAV2_1act_plasma_membrane)) blue _h_6386 MYC_Max_nucleus_v2 _h_5960 blue TSC1_TSC2_1act grey blue _h_456_1 Lethal_Factor_cytoplasm _h_6279 blue TSP1 grey _h_2127 blue LRP5 and N_cadherin_p120_catenin_beta_catenin_alpha_catenin_integral_to_membrane grey red red red red blue _h_6383 (FGFR_FGF2_complex or RUNX2_1act) red grey red grey red grey _h_2737 blue TAp73a__tetramer__nucleus_v3 grey red _h_5399_2 blue HDAC1 _h_5399_3 blue HDAC1 grey _h_5399_1 blue HDAC1 red grey grey blue _h_5242 Erk1_1O_1act_1O_cytoplasm or Erk2_1O_1O_1act_cytoplasm grey red blue _h_4365 MRCK_1O_2O_1act or ROCK1_1act _h_309 blue TACE_1act blue _h_308 CDC42_GTP_1act_plasma_membrane or PDK1_1act_plasma_membrane or mTOR_1act red _h_304 blue CDK6_Cyclin_D1_1act _h_4076_5 blue (FOXO4_14_3_3_family_nucleus_14_3_3_E_FOXO4_1O_2O and Ran_GTP_Exportin_1) blue _h_306 H2O2 _h_301 blue POT1 and Rap1 and TIN2 and TRF1 and TRF2 _h_4076_2 blue (FOXO4_14_3_3_family_nucleus_FOXO4_1O_2O_YWHAS and Ran_GTP_Exportin_1) blue _h_303 p38_beta_1O_1O_1act _h_942_1 blue (CDK4_6_Cyclin_D_CDK4_Cyclin_D1 or CDK4_6_Cyclin_D_CDK4_Cyclin_D2 or CDK4_6_Cyclin_D_CDK4_Cyclin_D3 or CDK4_6_Cyclin_D_CDK6_Cyclin_D1 or CDK4_6_Cyclin_D_CDK6_Cyclin_D2 or CDK4_6_Cyclin_D_CDK6_Cyclin_D3) and not (CDK4_6_Cyclin_D_p16INK4a_v1_CDK4_Cyclin_D2_p16INK4a or CDK4_6_Cyclin_D_p16INK4a_v1_CDK4_Cyclin_D3_p16INK4a or CDK4_6_Cyclin_D_p16INK4a_v1_CDK4_p16INK4a_Cyclin_D1 or CDK4_6_Cyclin_D_p16INK4a_v1_CDK6_Cyclin_D2_p16INK4a or CDK4_6_Cyclin_D_p16INK4a_v1_CDK6_Cyclin_D3_p16INK4a or CDK4_6_Cyclin_D_p16INK4a_v1_CDK6_p16INK4a_Cyclin_D1) grey red grey blue _h_3509 E2F1_3_DP_nucleus_DP1_E2F1 or E2F1_3_DP_nucleus_DP1_E2F2 or E2F1_3_DP_nucleus_DP1_E2F3 blue _h_3508 PKC_alpha_1act_plasma_membrane _h_2479 blue alphav_beta3_Integrin_Vitronectin_integral_to_membrane grey grey grey blue _h_3502 (CBP_1act_nucleus or STAT1__dimer__1act_nucleus_v3) grey _h_3500 blue alphav_beta3_Integrin grey red grey blue _h_3504 CHK2 _h_2734 blue MYC_Max_nucleus_v2 red grey grey grey grey red grey grey grey red grey grey grey grey grey grey grey grey grey blue _h_4708 STAT6__dimer__ETS1_1act_nucleus grey _h_2985_2 blue WNT3A_FZD5_LRP6_1act_integral_to_membrane _h_2985_3 blue DVL1_cytoplasm _h_2985_1 blue DVL2_cytoplasm grey blue _h_5822 dNp63g__tetramer__nucleus _h_5823 blue iC3b blue _h_5820 Aurora_B _h_5821 blue (GTP_v1 and ( not (Ephrin_B1_EPHB3 or N_cadherin_Ca2__p120_catenin_beta_catenin_gamma_catenin_alpha_catenin_cell_cell_junction))) blue _h_5826 TAp73b__tetramer__nucleus _h_5824 blue PLGF_homodimer _h_5825 blue RAP1_GTP_1act_cell_cell_junction blue _h_5828 STAT6__dimer__1act_nucleus_v1 grey grey grey blue _h_1011 Erk2_1O_1O_1act red red red red red blue _h_1116 (( not Myb_1s_nucleus) and (((BRM_CEBP_nucleus_CEBPA_BRM or BRM_CEBP_nucleus_CEBPB_BRM) or BRM_CEBP_nucleus_CEBPD_BRM) or Myb_nucleus)) blue _h_6117 IL12_IL12R_TYK2_JAK2_1act_integral_to_membrane red grey _h_3178 blue TRAP_1_TGFBR1__dimer__1ina_integral_to_membrane grey _h_1010 blue Crk and Pyk2 and RAP1B_GTP_1act blue _h_1319 Cyclin_A_CDK1_2_CDK1_Cyclin_A or Cyclin_A_CDK1_2_Cyclin_A_CDK2 or Cyclin_B_CDK1_2_CDK1_Cyclin_E1 or Cyclin_B_CDK1_2_Cyclin_E1_CDK2 or Cyclin_E_CDK2 _h_4105_2 blue (JUN_2O_1act_nucleus and NFAT4_1act_nucleus) grey red grey grey _h_3174 blue FAK_1O_1O_1act_cytoplasm _h_3175 blue pro_uPA_1ina_extracellular_region red blue _h_6116 TAp63g__tetramer__1act_nucleus_v2 grey grey _h_2730 blue ATP and GRK1 grey red grey grey _h_4995 blue exocyst red blue _h_4997 IL23_IL23R_JAK2_TYK2_1act_integral_to_membrane blue _h_4996 HIF1A_ARNT_nucleus _h_4991 blue GRAP2_SLP76_1act blue _h_4990 RAS_family_GTP_1act_plasma_membrane_H_RAS_isoform_1_GTP_v1 or RAS_family_GTP_1act_plasma_membrane_N_RAS_GTP_v1 _h_4992 blue IL3_IL3RA_CSF2RB__dodecamer__JAK2_JAK2_SHC_1act_integral_to_membrane _h_874 blue not LAT_GRAP2_SLP76_VAV1_ITK_PLCgamma1_CBL_1ina_integral_to_membrane and (LAT_GRAP2_SLP76_VAV1_ITK_PLCgamma1_1act_integral_to_membrane or LAT_GRAP2_SLP76_VAV1_PLCgamma1_1act or Nephrin_NEPH1_podocin_PLCgamma1_membrane_raft or PDGF_BB_PDGFRB__dimer__PLCgamma1_1act_integral_to_membrane_v2 or PLC_beta3_1act or PLC_beta3_1act_cytoplasm or PLC_beta_1_1act or PLC_beta_1_1act_cytoplasm or PLC_beta_2_1act or PLC_beta_2_1act_cytoplasm or PLC_beta_2_1act_plasma_membrane or PLC_beta_3_1act_plasma_membrane or PLCgamma1_1O_1act_cytoplasm or PLCgamma1_1act or PLCgamma1_1act_1O or PLCgamma1_1act_1O_plasma_membrane or PLCgamma1_3O_1act_cytoplasm or PLCgamma2_1act or Src_family_SYK_family_BLNK_LAT_BTK_ITK_PLC_gamma_1act_SYK_Family_Kinases_active_1act_BTK_ITK_active_1act_LAT_10O_1act_Fyn_1O_1act_PLCgamma1_1act_2O or Src_family_SYK_family_BLNK_LAT_BTK_ITK_PLC_gamma_1act_SYK_Family_Kinases_active_1act_BTK_ITK_active_1act_LAT_10O_1act_PLCgamma1_1act_2O_LYN_1act_1O or Src_family_SYK_family_BLNK_LAT_BTK_ITK_PLC_gamma_1act_SYK_Family_Kinases_active_1act_BTK_ITK_active_1act_LAT_10O_1act_PLCgamma1_1act_2O_Lck_1O_1act or Src_family_SYK_family_BLNK_LAT_BTK_ITK_PLC_gamma_1act_SYK_Family_Kinases_active_1act_BTK_ITK_active_1act_LAT_10O_1act_PLCgamma1_1act_2O_Src_1act_1O) grey red _h_2751_1 blue YWHAQ blue _h_5885 HIF2A_ARNT_nucleus_v3 grey _h_4371 blue 14_3_3_E and Akt1_1O_1act_1O_1O_plasma_membrane and TERT grey red _h_2751_6 blue YWHAS _h_5509_3 blue CRY1_cytoplasm _h_2751_5 blue YWHAZ grey grey grey _h_2125 blue PKC_theta_1O_1act_plasma_membrane grey grey red _h_1115 blue S1P5 and S1P_extracellular_region grey grey red _h_3865 blue TACE_1act _h_2857 blue RAF1_1O_1O_1act_plasma_membrane _h_5081 blue ((((BMP2_4__homodimer__extracellular_region and BMPR1A_1B__homodimer__integral_to_membrane) and BMPR2__homodimer__1act_integral_to_membrane) and RGM_family) and USAG1) blue _h_1036_28 Arf6_GTP_1act or Arf6_GTP_1act_plasma_membrane blue _h_1036_27 Arf6_GTP_1act or Arf6_GTP_1act_plasma_membrane blue _h_1036_26 Arf6_GTP_1act or Arf6_GTP_1act_plasma_membrane blue _h_1036_25 Arf6_GTP_1act or Arf6_GTP_1act_plasma_membrane blue _h_126 (Ca2__cytoplasm or DAG_v1) blue _h_1036_23 Arf6_GTP_1act or Arf6_GTP_1act_plasma_membrane blue _h_1036_22 Arf6_GTP_1act or Arf6_GTP_1act_plasma_membrane blue _h_1036_21 Arf6_GTP_1act or Arf6_GTP_1act_plasma_membrane blue _h_1036_20 Arf6_GTP_1act or Arf6_GTP_1act_plasma_membrane grey grey grey blue _h_3476 IL12_IL12R_TYK2_JAK2_1act_integral_to_membrane blue _h_3426 STAT6__dimer__1act_nucleus_v1 blue _h_3030_1 GPC3_heterodimer_1act_plasma_membrane blue _h_3030_2 GPC3_heterodimer_1act_plasma_membrane grey red grey _h_3473 blue KIT and not (Gleevec or PKC_1act_cytoplasm or SHP1_1act_cytoplasm or SHP2_1act_cytoplasm) grey _h_425_1 blue CEBPB_1O_1act and p300_nucleus _h_5852_2 blue IRF4_nucleus and NFAT1_1O_7O_2s_1act_nucleus _h_5852_3 blue MAF_nucleus and NFATc_1act_nucleus _h_5852_1 blue IRF4_nucleus and NFAT4_1act_nucleus red grey red red grey blue _h_1118 DEP1_1act _h_6216_1 blue TAB1 and TRAF6_1u_1act and not (p38_alpha_1O_1O_1act_v2 or p38_beta_1O_1O_1act) red red grey _h_5747_2 blue FOS_nucleus grey grey red grey grey grey grey grey grey grey grey red blue _h_3478 PDK1_1act_plasma_membrane red red _h_1404_2 blue Smad3_2O_1act red grey grey grey red grey grey grey grey grey red grey grey grey grey _h_1174 blue EGFR_EGFR_EGF_EGF_1act_integral_to_membrane_v1 and GTP_v1 red grey red grey _h_5266 blue Chromosomal_passenger_complex_1act_chromosome red blue _h_815 E_cadherin_Ca2__beta_catenin_alpha_catenin_p120_catenin_cell_cell_junction_v1 blue _h_5267 ((((((((ErbB3 or IL2_IL2R_alpha_beta_gamma_JAK1_LCK_JAK3_SHC_GAB2_GRB2_SOS1_SHP2_PI3K_1act_integral_to_membrane) or Insulin_Receptor_Insulin_GRB14_PDK1) or PDK1_1O_1act) or PI3K_1act_plasma_membrane_v1) or PI3K_beta_1act_plasma_membrane) or PI_3_4_5_P3_plasma_membrane) or RAC1_GTP_1act_v1) or alpha6_beta4_Integrin_Laminin_hemidesmosome) red grey red blue _h_1026 ELK1_2O_1act_nucleus _h_5229 blue p53__tetramer__nucleus_v2 blue _h_1024 RBPJ_NICD_1act_nucleus blue _h_816 ((SMAD2_3_SMAD4_SP1_MIZ_1_1act_nucleus_SMAD2_2O_1act_SP1_SMAD4_MIZ_1 or SMAD2_3_SMAD4_SP1_MIZ_1_1act_nucleus_SP1_Smad3_2O_1act_SMAD4_MIZ_1) and ( not (MYC_MIZ_1 or SMAD3_SMAD4_1ina_nucleus))) blue _h_1022 mTOR_1O_1act blue _h_1023 CaM_Ca2_ blue _h_1020 ((STAT5A_B__dimer__1act_nucleus or STAT5A__dimer__active_1act_nucleus_v2) or STAT5B__dimer__1act_nucleus) grey grey _h_5221 blue uPA_uPAR_alpha5_beta1_Integrin_1act_integral_to_membrane blue _h_5222 CREB1_1O_1act_nucleus or MEF2C_1p_1act_nucleus _h_5223 blue Laminin_5_basement_membrane blue _h_5224 ETA_receptor_Endothelin_1_integral_to_membrane _h_5225 blue KDEL_1act blue _h_1028 MRN_complex_ATM_MDC1_H2AX_RNF8_53BP1_BRCA1_1act_site_of_double_strand_break_v2 red _h_6038 blue PAI_1 grey grey blue _h_5051_80 (RAS_family_GTP_1act_plasma_membrane_H_RAS_isoform_1_GTP_v1 or RAS_family_GTP_1act_plasma_membrane_N_RAS_GTP_v1) red red grey blue _h_6033 NEF grey _h_6035 blue RB1 and TAp73a__tetramer__nucleus_v3 _h_6037 blue ASK1_cytoplasm and Caspase_2s and FADD and RAIDD and TNFR1A_BAG4_TNF_alpha_v1 and TRADD and TRAF1 and TRAF2 and cIAP2 _h_118_3 blue YWHAS and chibby grey _h_1108_1 blue Axin1_APC_GSK3_beta_catenin_cytoplasm_v1 _h_3774 blue IL1RN blue _h_3775 N_cadherin_Ca2__p120_catenin_beta_catenin_gamma_catenin_alpha_catenin_cell_cell_junction _h_3776 blue IL2R_beta_JAK1_LCK_integral_to_membrane and IL2R_gamma_JAK3_integral_to_membrane and IL2_1O_extracellular_region and not (IL2R_beta_JAK1_LCK_CISH_1act_integral_to_membrane or IL2R_beta_JAK1_LCK_SOCS1_1act_integral_to_membrane or IL2R_beta_JAK1_LCK_SOCS3_1act_integral_to_membrane or IL2R_gamma_JAK3_SOCS1_1act_integral_to_membrane) grey grey grey grey grey red _h_2874_2 blue PAK1_betaPIX_PKL_NCK1_2_1act_cytoplasm_PAK1_1act_PKL_1act_3O_NCK1_betaPIX_1act _h_631 blue Fibrillin_1 red _h_146 blue CSF1R and M_CSF and alphav_beta3_Integrin and p130Cas grey grey _h_633 blue ARAP1_1act_cell_leading_edge or FAK_Src_Yes_Fyn_RasGAP_p190RhoGAP_1act_cell_leading_edge_Fyn_1O_1act_FAK_6O_1act_RasGAP_p190RhoGAP_1act_1O or FAK_Src_Yes_Fyn_RasGAP_p190RhoGAP_1act_cell_leading_edge_Src_1act_1O_FAK_6O_1act_RasGAP_p190RhoGAP_1act_1O grey blue _h_632 (( not SHIP) and (PI3K_1act_plasma_membrane_v2 or PI_3_4_5_P3)) _h_6076 blue JUNB__dimer__1act_nucleus_v2 red grey red red grey red blue _h_6070 FOXM1C_2O_1act_nucleus _h_2052 blue SRF_nucleus grey blue _h_6071 not XIAP and (APAF_1_Caspase_9_1act or Caspase_2_1act or Granzyme_B_cytoplasm) red red grey red grey _h_5802_1 blue Ca2__CaM_1act and IFN_gamma_IFN_gammaR_JAK1_JAK1_JAK2_JAK2_1act _h_1678 blue eNOS grey grey red grey red red _h_4176 blue alpha8_beta1_Integrin_integral_to_membrane grey red red _h_4172 blue alphav_beta3_Integrin_integral_to_membrane blue _h_4171 Gamma_Secretase_plasma_membrane_v2 grey _h_4548_2 blue HDAC1_nucleus and RXRs_RARs_NRIP1_9cRA_RXR_alpha_NRIP1_2O_1O_RAR_alpha_9cRA red _h_4113 blue GATA3 red _h_4179 blue Osteopontin _h_5829_1 blue LPA grey grey red red grey _h_4143 blue IL6RA_integral_to_membrane red grey grey red grey red blue _h_2828 EHD4_1act blue _h_2827 ((STAT3__dimer___1act or STAT4__dimer__1act_nucleus_v2) or T_bet) blue _h_2826 p53__tetramer__nucleus_v2 _h_2825 blue Estrogen_receptor_alpha grey blue _h_2823 PKC__alpha_beta_epsilon_zeta__1act_cytoplasm blue _h_2822 SMAD4_SMAD1_5_8__dimer__1act_nucleus blue _h_2820 RAC1_GTP_1act_plasma_membrane blue _h_1343 Lethal_Factor_cytoplasm and not Epigallocatechin_3_gallate__EGCG_ red grey grey red red _h_2874_1 blue PAK1_betaPIX_PKL_NCK1_2_1act_cytoplasm_PAK1_1act_PKL_1act_3O_NCK1_betaPIX_1act grey red grey red blue _h_5409 NFAT1_FOXP3 blue _h_4933 GSK3beta_cytoplasm blue _h_5182 PI_3_4_5_P3_plasma_membrane red _h_4684 blue VEGFR2__dimer__VEGFA__dimer__1act_integral_to_membrane_v1 red red red blue _h_1036_48 Arf6_GTP_1act or Arf6_GTP_1act_plasma_membrane blue _h_4505 p210_bcr_abl blue _h_4502 PDK1_1act_plasma_membrane or PI_3_4_5_P3_plasma_membrane _h_4503 blue Fibronectin_extracellular_matrix blue _h_4500 IRS1_1act_1O blue _h_4501 TBP_nucleus and not (BRCA1 or MYC_Max_nucleus_v4) red red grey _h_4508 blue E2_ERB__dimer__1act_nucleus grey grey _h_4935 blue ErbB2_integral_to_membrane and NRG1_extracellular_region red blue _h_3229 RAF1_1O_1act_v2 blue _h_4934 TCF4_beta_catenin_1act_nucleus grey red red blue _h_4233_4 Ephrin_B1_EPHB1_2_1act_integral_to_membrane_v1 grey grey red grey grey blue _h_5046 ((STAT5A_B__dimer__1act_nucleus or STAT5A__dimer__active_1act_nucleus_v2) or STAT5B__dimer__1act_nucleus) red grey _h_4525 blue SHP2_1ina_cytoplasm red grey red grey blue _h_111 CREB1_1act_nucleus or ELK1_SRF_1act_nucleus_v1 _h_112 blue Syndecan_2 red blue _h_114 PPM1A blue _h_115 SIRT1_nucleus blue _h_116 Myb_nucleus red grey grey grey grey red blue _h_3731 (AR_T_DHT_nucleus or PAR4) blue _h_1235 FOXO3A_SIRT1_1act_nucleus grey grey grey grey grey red grey grey grey grey grey grey grey blue _h_71 p53__tetramer__nucleus_v2 _h_72 blue Laminin_alpha3 blue _h_958 ((AIB1_nucleus or E2_ERA_nucleus) or FOXA1_nucleus) blue _h_74 MKK3_1O_1O_1act or MKK6_1O_1O_1act _h_75 blue RDH12_plasma_membrane and all_trans_retinal blue _h_76 NIK_1act grey _h_78 blue YWHAZ blue _h_79 DEP1_1act red grey grey grey grey red red red _h_2050 blue E_cadherin_Ca2__beta_catenin_alpha_catenin_cell_cell_junction_v1 and not (CDC42_GTP_IQGAP1_1act or RAC1_GTP_IQGAP1_1act_plasma_membrane) blue _h_1840 zyxin_1act_focal_adhesion red grey _h_1843 blue NRAGE blue _h_1845 Calcineurin_A_beta_1act_cytoplasm grey blue _h_1847 TCF4E_beta_catenin_p300_1act_nucleus blue _h_4064 HGS_1act_early_endosome or RAB7_GTP_1act grey grey blue _h_5039 (MIZ_1 and ( not HDAC1_nucleus)) grey _h_5035 blue uPAR__dimer__plasma_membrane _h_5034 blue ACTN1 blue _h_1232 (beta_catenin_TCF1_CtBP_CBP_TLE1_AES_SMAD4_nucleus and ( not CtBP_CBP_TCF1_TLE1_AES_1act_nucleus)) grey grey blue _h_5030 (((JUN_FOSNFAT1_c_4_1act_nucleus_c_Jun_2O_NFAT1_1O_7O_2s_1act_nucleus_FOS_1O_1O or JUN_FOSNFAT1_c_4_1act_nucleus_c_Jun_2O_NFAT4_1act_nucleus_FOS_1O_1O) or JUN_FOSNFAT1_c_4_1act_nucleus_c_Jun_2O_NFATc_1act_nucleus_FOS_1O_1O) and ( not ((NFAT1_c_4_ICER1_1act_nucleus_ICER1_NFAT1_1O_7O_2s_1act_nucleus or NFAT1_c_4_ICER1_1act_nucleus_ICER1_NFAT4_1act_nucleus) or NFAT1_c_4_ICER1_1act_nucleus_ICER1_NFATc_1act_nucleus))) blue _h_5033 Gamma_Secretase_plasma_membrane_v1 blue _h_5032 p38_alpha_1O_1O_1act_v2 or p38_beta_1O_1O_1act grey blue _h_1909 (STAT1__dimer__1act_v1 or STAT3__dimer___1act) blue _h_1908 (FOXA2_nucleus_v1 and ( not FOXA1_nucleus)) _h_5100 blue BMP9__dimer__extracellular_region and BMPR2__homodimer__integral_to_membrane and Endoglin__dimer__integral_to_membrane blue _h_5545 GRK5_GRK6_1act blue _h_1904 PI3K_1act_plasma_membrane_v2 blue _h_1906 (FOXA2_nucleus_v1 and ( not FOXF1_nucleus)) red grey blue _h_1902 p53__tetramer__nucleus_v2 blue _h_5899_1 ErbB2_ErbB3_neuregulin_1_beta_1act_integral_to_membrane_v1 grey red _h_5102 blue IL4_IL4R_JAK1_IL2R_gamma_JAK3_1act_integral_to_membrane and SHIP_cytoplasm blue _h_1036_41 Arf6_GTP_1act or Arf6_GTP_1act_plasma_membrane blue _h_5899_4 ErbB2_ErbB3_neuregulin_1_beta_1act_integral_to_membrane_v1 blue _h_5899_7 ErbB2_ErbB3_neuregulin_1_beta_1act_integral_to_membrane_v1 blue _h_5899_6 ErbB2_ErbB3_neuregulin_1_beta_1act_integral_to_membrane_v1 blue _h_5899_9 ErbB2_ErbB3_neuregulin_1_beta_1act_integral_to_membrane_v1 grey red red grey grey grey red grey blue _h_5106 PIP4K2A_1act_plasma_membrane grey red red red red grey blue _h_6358 PDGF_BB_PDGFRB__dimer__1act_integral_to_membrane_v1 grey red red blue _h_66_4 Ran_GTP_Exportin_1 blue _h_66_5 Ran_GTP_Exportin_1 blue _h_66_2 Ran_GTP_Exportin_1 _h_1396 blue IRS1 red blue _h_3006 EGFR_EGFR_EGF_EGF_1act_endosome_v2 red grey _h_3007 blue VAV2 blue _h_1849_2 p38_alpha_1O_1O_1act_v2 grey blue _h_1849_3 p38_alpha_1O_1O_1act_v2 grey _h_6131 blue TFGBI red grey grey red blue _h_1849_1 p38_alpha_1O_1O_1act_v2 red grey blue _h_2129 ((((AP1 or CBP) or GATA2) or HIF1A_ARNT_nucleus) or p300) grey red grey _h_3567_4 blue 9cRA and RAR_alpha and Src_1 _h_3567_1 blue 9cRA and Rar_gamma1 and Src_1 _h_3567_3 blue 9cRA and Rar_gamma1 and Src_1 red red grey blue _h_4348 TAp63g__tetramer__1act_nucleus_v2 grey _h_2239_2 blue WDR5 red _h_4346 blue Syndecan_1 blue _h_4347 EPO_EPOR__dimer__JAK2 blue _h_4340 Erk2_1O_1O_1act red blue _h_4342 Pyk2_1O_1act_cytoplasm red blue _h_2659_2 (ROCK2_1act or ROCK_1act) grey grey _h_3008 blue 911_complex blue _h_2018 FGFR_FGF_Syndecan_2_1act blue _h_5261 FOXA2_nucleus_v1 blue _h_2016 p53__tetramer__nucleus_v2 blue _h_2017 ((FOXO1_3a_4_beta_catenin_FOXO4_beta_catenin or FOXO1_3a_4_beta_catenin_beta_catenin_FOXO1) or FOXO1_3a_4_beta_catenin_beta_catenin_FOXO3A) blue _h_1036_44 Arf6_GTP_1act or Arf6_GTP_1act_plasma_membrane blue _h_2015 Myb_nucleus blue _h_2012 RAF1_4O_1act_plasma_membrane blue _h_2010 IL2_IL2R_1act_integral_to_membrane _h_2011 blue SMAD2_SMAD2_SMAD4_FOXH1_1act_nucleus and p300 _h_1279 blue SHP2_1act_1O_nucleus _h_1278 blue Vitronectin_extracellular_matrix grey grey _h_1273 blue RAC1_GTP_1act_plasma_membrane blue _h_1272 p38_alpha_1O_1O_1act_v2 _h_1270 blue Laminin_alpha3 blue _h_1277 (( not Ca2__cytoplasm) and ((((((((((CaT1_1act_plasma_membrane or Gi_family_GTP_1act) or IFN_gamma_IFN_gammaR_JAK1_JAK1_JAK2_JAK2_1act) or L_type_voltage_dependent_calcium_channel) or ORAI1_1act_plasma_membrane) or PKC_theta_FLNA) or TCR_CD3_MHC_II_CD4_LCK_ZAP_70_3BP2_1act_integral_to_membrane_v1) or TRPC3_1act) or TRPC6_1act) or cGMP_CNG_Channel_1act) or cGMP_Cone_CNG_Channel_1act)) blue _h_1276 ( not JUN_FOS_1act_nucleus_v2) grey blue _h_4706 Ephrin_A1_EPHA2_1act_integral_to_membrane grey _h_4217 blue NEDD8_UBC12_UBA3 grey grey red blue _h_1036_88 Arf6_GTP_1act or Arf6_GTP_1act_plasma_membrane grey grey _h_5672 blue SMAD1_cytoplasm grey grey _h_4707 blue (RhoA_GDP_1ina_plasma_membrane and ((((((((((Ephrin_A1_EPHA1_4_Ephexin_1act_integral_to_membrane or Ephrin_A1_EPHA2_1act_integral_to_membrane) or Ephrin_A1_EPHA4_VSM_RhoGEF_1act_integral_to_membrane) or Ephrin_A2_EPHA3_4_5_6_7) or Ephrin_A5_EPHA3_4_5_6_7_1act) or Ephrin_A5_EPHA3_Crk_1act_integral_to_membrane) or G13_GTP_1act_plasma_membrane_v1) or G13_GTP_1act_plasma_membrane_v2) or G13_GTP_p115RhoGEF_1act_plasma_membrane) or RAS_family_GTP_1act_plasma_membrane_H_RAS_isoform_1_GTP_v1) or RAS_family_GTP_1act_plasma_membrane_N_RAS_GTP_v1)) grey red grey grey blue _h_5899_37 ErbB2_ErbB3_neuregulin_1_beta_1act_integral_to_membrane_v1 red grey red grey _h_5778 blue VEGFA_homodimer_extracellular_region_v1 and VEGFR2_integral_to_membrane blue _h_2658 Arf6_GTP_1act_plasma_membrane red red grey blue _h_1036_81 Arf6_GTP_1act or Arf6_GTP_1act_plasma_membrane red grey grey _h_4189 blue GRB2_SOS1_SHC red blue _h_1036_83 Arf6_GTP_1act or Arf6_GTP_1act_plasma_membrane _h_1846 blue BoNT_E_Light_Chain_1act_cytoplasm red red grey red blue _h_3699 JUND__dimer__1act_nucleus _h_3698 blue AR_T_DHT_nucleus grey red blue _h_3693 ( not E2F1_DP_nucleus_v4) _h_3692 blue alphav_beta3_Integrin_integral_to_membrane grey blue _h_3690 E_cadherin_Ca2__beta_catenin_gamma_catenin_alpha_catenin_p120_catenin_cell_cell_junction_v2 grey blue _h_3696 JUN_ATF2_1act_nucleus _h_3695 blue HDAC4_nucleus and SIRT1_nucleus red grey grey grey grey grey grey blue _h_5758_3 PI_3_4_5_P3_plasma_membrane blue _h_2652 alphaM_beta2_Integrin_RAGE_HMGB1 blue _h_5758_1 PI_3_4_5_P3_plasma_membrane red _h_4181 blue ARF6_GDP_1ina red red grey _h_3525 blue HDAC3_nucleus _h_3524 blue PA63_extracellular_region _h_3527 blue Torsin_A _h_3526 blue XRCC4__dimer__Ligase_IV blue _h_3521 (AR_T_DHT_nucleus and ( not TZF_L_nucleus)) red _h_3523 blue JUNB_nucleus _h_3522 blue H2AX_1O_nucleus grey red blue _h_4185 MYC_Max_nucleus_v2 _h_3529 blue ER_alpha_nucleus grey grey grey _h_5592 blue LPA_LPA2 grey grey red blue _h_5596 FOXM1B_nucleus _h_5597 blue Caveolin_1 grey red _h_5598 blue CBL_cytoplasm and betaPIX_1O_1act red grey grey grey grey _h_6124 blue alphav_beta3_Integrin and (FGF2_extracellular_region or Vitronectin) grey grey red grey blue _h_5268 TAp73a__tetramer__nucleus_v3 red blue _h_1036_119 Arf6_GTP_1act or Arf6_GTP_1act_plasma_membrane grey grey red grey red grey grey blue _h_858 Parkin_cytoplasm or UbcH7 red grey grey _h_1296 blue B7_family_CD28_1act_integral_to_membrane_v2 and ZAP_70 blue _h_327 (ETS1 or TNF_alpha_extracellular_region) and not (Thrombin_extracellular_region or beta2_estradiol) blue _h_326 Akt1_1O_1act_1O_1O_plasma_membrane grey blue _h_324 mTORC1_1act blue _h_323 ((ATF1_1O_1act_nucleus or JNK2_1O_1act_1O_nucleus) or Jnk1_1O_1act_1O_nucleus) grey _h_321 blue ZO2 red grey red grey _h_519 blue FOSB_nucleus red grey blue _h_5996 EGR1_nucleus grey red grey grey grey red grey grey grey grey red red grey blue _h_3446 IL12_IL12R_TYK2_JAK2_1act_integral_to_membrane or IL18_IL18R_1act red grey red _h_4979 blue BCL3_nucleus blue _h_4978 CaM_1act_1O _h_4977 blue ER_alpha_Gai_GDP_Gbeta_gamma_1act_plasma_membrane red grey red red blue _h_4972 USP8_1O_1act grey red blue _h_555_2 ((((((((((((CD40_CD40L__trimer__TRAF2__trimer__MEKK1_membrane_raft or CD40_CD40L__trimer__TRAF6_integral_to_membrane) or DLK) or GNB1_GNG2_1act_cytoplasm) or IL2_IL2R_alpha_beta_gamma_JAK1_LCK_JAK3_SHC_1act_integral_to_membrane) or MKK3_1O_1O_1act) or MKK6_1O_1O_1act) or MKK6_1act) or RAC1_CDC42_GTP_PAK_family_1act_plasma_membrane_Rac1_PAK1_1act_GTP_v1) or RAC1_CDC42_GTP_PAK_family_1act_plasma_membrane_Rac1_PAK2_1act_GTP_v1) or RAC1_OSM_MEKK3_MKK3_1act_plasma_membrane) or Syk_1O_1act) or TRAF6_MEKK3_1act) _h_4283 blue ATP or CAPRI_1act_plasma_membrane or Ca2__v1 grey grey blue _h_6337_3 ((BMP9_ACTR2_Endoglin_ALK1__dimer__1act_integral_to_membrane or BMP9_BMPR2_Endoglin_ALK1__dimer__1act_integral_to_membrane) or BMP9_BMPR2_Endoglin_ALK1__dimer__CK2B_1act_integral_to_membrane) red _h_2216_1 blue (NGF__dimer__p75_NTR__PKA_1act_membrane_raft and RhoA_B_C_GTP_1act_v2) red grey grey _h_1886 blue uPA_uPAR_alphav_beta5_Integrin_1act_integral_to_membrane red grey blue _h_4709 (AR_T_DHT_nucleus and ( not HNRNPA1)) blue _h_355 VEGFR3_VEGFC_D_Crk_1act_plasma_membrane _h_5578 blue alpha6_Integrin and beta4_integrin red _h_1370_1 blue CBP_nucleus grey grey grey red grey grey grey red red red grey grey grey grey grey blue _h_6425 FOXM1B_nucleus grey _h_625 blue Vitronectin_extracellular_region grey red blue _h_429_2 Exportin_1 blue _h_429_6 Exportin_1 grey grey blue _h_797 TNF_alpha_TNFR1A_TRADD_MADD_cIAP2_RIP_TRAF2_RAIDD red grey blue _h_2434_41 ((EGFR_EGFR_1act_integral_to_membrane_v1 or EGFR_EGFR_EGF_EGF_GRB2_GAB1_1act_integral_to_membrane_v1) and ( not (EGFR_EGFR_1ina_integral_to_membrane or EGFR_EGFR_EGF_EGF_GRB2_GAB1_1ina_integral_to_membrane))) grey grey grey grey grey grey grey grey grey blue _h_2760_4 CK1_alpha or CK1_epsilon blue _h_2434_46 ((EGFR_EGFR_1act_integral_to_membrane_v1 or EGFR_EGFR_EGF_EGF_GRB2_GAB1_1act_integral_to_membrane_v1) and ( not (EGFR_EGFR_1ina_integral_to_membrane or EGFR_EGFR_EGF_EGF_GRB2_GAB1_1ina_integral_to_membrane))) blue _h_5775 cGMP_CNG_Channel_1act or cGMP_Cone_CNG_Channel_1act red grey grey blue _h_2434_48 ((EGFR_EGFR_1act_integral_to_membrane_v1 or EGFR_EGFR_EGF_EGF_GRB2_GAB1_1act_integral_to_membrane_v1) and ( not (EGFR_EGFR_1ina_integral_to_membrane or EGFR_EGFR_EGF_EGF_GRB2_GAB1_1ina_integral_to_membrane))) grey blue _h_6020_1 SMO_beta_Arrestin2_1act_clathrin_coat_of_coated_pit blue _h_4212 STAT6__dimer__1act_nucleus_v1 red grey blue _h_3727 TCF4E_beta_catenin_1act_nucleus red _h_1313_4 blue YWHAZ_nucleus grey _h_1313_6 blue YWHAB_nucleus _h_1313_1 blue FOXO1_1O_2O_nucleus _h_1313_2 blue FOXO1_1O_2O_nucleus grey grey blue _h_1036_4 Arf6_GTP_1act or Arf6_GTP_1act_plasma_membrane red red red grey red blue _h_2466 Exportin_1_Ran_NUP214 blue _h_2465 B_cell_antigen_BCR_complex_LYN_v2 blue _h_2464 TAp63g__tetramer__1act_nucleus_v2 blue _h_2463 DAG_v2 blue _h_2462 MEK1_3O_1act blue _h_2461 (( not (HDAC2_nucleus or p53__tetramer__nucleus_v7)) and ((((BRG1 or GCN5_L_ADA2B_TAF9_nucleus) or HZF_nucleus) or POU4F1_nucleus) or p53__tetramer__nucleus_v6)) red grey grey red grey _h_5202 blue ELK1_2O_1act_nucleus grey _h_5200 blue Delta_1 grey blue _h_5206 CHK1_2O_1act_nucleus red _h_5204 blue JUN_2O_2O_nucleus grey _h_5209 blue GTP_v1 and TXA2_extracellular_region and not TXA2_TP_alpha_1ina_integral_to_membrane blue _h_2760_1 CK1_alpha or CK1_epsilon red grey grey _h_6010 blue MDM2_SUMO1_nucleus and (PIAS1_nucleus or PIASxBeta_nucleus) _h_6011 blue MYOD_1act_3N and SIRT1_nucleus blue _h_6016 (FOXO3A_nucleus and ( not FOXO3A_SIRT1_1act_nucleus)) blue _h_6017 ( not JUN_FOSB_1act_nucleus) _h_6014 blue alphav_beta3_Integrin _h_6015 blue BCL10 and CARD11_1act and MALT1 blue _h_1048 TAp63g__tetramer__1act_nucleus_v2 _h_2258_2 blue PI3K_Class_I_family_CBL_b_PI3K_CBL_b _h_2258_1 blue PI3K_Class_I_family_CBL_b_PI3K_gamma_p84_CBL_b blue _h_6251 ATF2_2O_1act_nucleus grey grey grey _h_798 blue Alpha_Synuclein_1act_1O_1O_cytoplasm and HSP70 grey grey grey blue _h_3758 CHK1_2O_1act_nucleus grey grey grey _h_3753 blue NT_4_5__dimer__extracellular_region _h_3750 blue VEGFR1_integral_to_membrane red grey blue _h_3757 RSK2_1act_3O_1O_nucleus red grey blue _h_5516_2 (Ca2__cytoplasm or DAG_v2) grey grey _h_2230_2 blue MDM2_UBCH5_nucleus red grey grey _h_696 blue Cone_Metarhodopsin_II_1ina red red grey blue _h_807_26 (FASLG_FAS__trimer__Src_Syk_1act_integral_to_membrane or TRAIL__trimer__extracellular_region) grey grey _h_663_1 blue SMAD6_7_SMURF1_Smad7_SMURF1 blue _h_4519_2 (IL18_IL18R_1act or MKK4_1O_1O_1act) grey grey grey grey red grey grey red red red blue _h_3623 E2_ERA__dimer__ERAP140_1act_nucleus grey _h_5363 blue Ca2__cytoplasm grey red red red red grey grey grey blue _h_4151 ARF6_GDP_1ina _h_4152 blue E_cadherin_beta_catenin_alpha_catenin_basolateral_plasma_membrane_v1 blue _h_4155 TCPTP_p45_nucleus grey blue _h_4157 ETA_receptor_Endothelin_1_integral_to_membrane _h_4156 blue insulin_extracellular_region red red blue _h_5368 AP1_1act_nucleus grey blue _h_693 STAT6__dimer__1act_nucleus_v1 red blue _h_6256 Aurora_B or Aurora_C_Aurora_B_INCENP_chromosome_v1 blue _h_1148 Ephrin_B_EPHB2_1act_integral_to_membrane grey grey blue _h_5134 NUP153 or NUP214 or importin_alpha _h_2808 blue JUN_FOS_1act_nucleus_v1 grey grey blue _h_2803 CK1_gamma_1act_membrane_raft blue _h_2802 TAp73a__tetramer__nucleus_v3 grey blue _h_2804 DAB1_CRKL_C3G or EPO_EPOR__dimer__JAK2 _h_2807 blue beta_Klotho blue _h_2806 p210_bcr_abl grey grey blue _h_6310 Aurora_B grey grey blue _h_6313 SHH1L_filamentous_actin red grey blue _h_1472 ( not (JUN_JUN_FOS_1act_nucleus_v2_JUN or JUN_JUN_FOS_1act_nucleus_v2_JUN_FOS)) blue _h_2520 Erk2_1O_1O_1act red blue _h_691 EphB2_1act blue _h_1475 SHP2_GAB1_GRB2_FRS2_FGFR_FGF_Syndecan_2 or netrin_1_UNC5B_PIKE_L_GTP_1act_integral_to_membrane blue _h_807_21 FASLG_FAS__trimer__Src_Syk_1act_integral_to_membrane or TRAIL__trimer__extracellular_region red _h_1477 blue VHL_Elongin_B_Elongin_C_RBX1_CUL2_1act grey _h_6316 blue ET3_extracellular_region blue _h_4453 FOXA2_nucleus_v1 grey _h_4560 blue B_cell_antigen_BCR_complex_Btk_LYN_SYK_BLNK_PLCgamma2 _h_4562 blue EGFR_EGFR_EGF_EGF_1act_integral_to_membrane_v1 and PPP2R1A_PPP2CA _h_4563 blue ADAM10 and NOTCH1_precursor_Deltex_homolog_1_1act blue _h_4564 (TAp63g__tetramer__p300_1act_nucleus and ( not TAp63g__tetramer__p14ARF_1ina_nucleus)) _h_4565 blue not Akt1 and (Caspase_3_1act or Caspase_7_1act) grey blue _h_4567 LAT_GRAP2_SLP76_HPK1_HIP_55_CRK_family_1act_integral_to_membrane_LAT_10O_GRAP2_HPK1_1O_Crk_HIP_55_2O_SLP76_3O or LAT_GRAP2_SLP76_HPK1_HIP_55_CRK_family_1act_integral_to_membrane_LAT_10O_GRAP2_HPK1_1O_HIP_55_2O_CRKL_SLP76_3O _h_4568 blue ATP and PIP5K1A_1act_plasma_membrane_v1 _h_2603 blue EGFR_integral_to_membrane and ErbB3 blue _h_2206 IFN_gamma_IFN_gammaR_JAK1_JAK1_JAK2_JAK2_1act red red grey red red grey _h_377 blue NPAS2_nucleus red grey red red grey grey grey grey blue _h_2900 (IRF1 and ( not STAT1__dimer__PIASy_1ina_nucleus)) grey grey grey red blue _h_2902 DAG_v2 red blue _h_1304 E2_ERA__dimer__FE65_AICD_1act_nucleus grey grey blue _h_172 STAT6__dimer__1act_nucleus_v1 blue _h_1303 TAp63a__tetramer__1act_nucleus_v3 blue _h_170 CBP_nucleus red grey grey blue _h_174 TCF4_beta_catenin_Cbp_1act_nucleus grey red blue _h_1566 MYC_Max_nucleus_v2 blue _h_2906 IL23_IL23R_JAK2_TYK2_1act_integral_to_membrane red grey grey red blue _h_1300 Jnk1_1act_nucleus grey grey blue _h_5122_2 (Ca2__cytoplasm or DAG_v2) blue _h_5785 beta_catenin_nucleus blue _h_5784 HAKAI_1p_1act_early_endosome blue _h_5783 AR_T_DHT_nucleus or SRG3 or Src_1 blue _h_5781 cIAP1_cIAP2_TRAF2_TRAF3 blue _h_5780 HIF1A_ARNT_nucleus grey _h_5789 blue Aurora_B_midbody _h_5788 blue PDE6C_1act or PDE6H_GNAT2_GTP_1act grey blue _h_4574_15 EHD4_1act grey grey red red red blue _h_1862 MRN_complex_ATM_MDC1_H2AX_RNF8_53BP1_1act_site_of_double_strand_break grey blue _h_1860 SYNJ1_1ina_1O _h_1861 blue Dok_R and Tie2_Ang1_1act _h_1866 blue JUN_FOS_1act_nucleus_v4 and TCF4E red blue _h_1864 dNp63g__tetramer__nucleus blue _h_99 (AR_T_DHT_nucleus or PIAS3) blue _h_96 SET8 _h_97 blue GRB7 _h_1868 blue 9cRA_cytoplasm _h_1308 blue RAC1_GDP_1ina_basolateral_plasma_membrane and not ARF6_GTP_NME1_Tiam1_basolateral_plasma_membrane _h_92 blue HDAC1 _h_93 blue HDAC4_nucleus _h_90 blue alpha4_beta1_Integrin_integral_to_membrane_v1 _h_91 blue Phosphatidic_acid and RICTOR _h_4454 blue VLDLR grey blue _h_3039 dNp63g__tetramer__nucleus blue _h_4763 MYC_Max_nucleus_v2 _h_3037 blue PP2A_Bprime _h_3036 blue MDC1_1p_nucleus _h_3035 blue ATR_ATRIP_nucleus_v2 blue _h_3034 Aurora_A or ER_alpha_Oestrogen_1act or IL2_extracellular_region or PDK1_1act_plasma_membrane or PI_3_4_5_P3_plasma_membrane _h_3033 blue Laminin_1_basement_membrane _h_4760 blue Spermine and not Spermine grey red grey grey grey blue _h_5511 (( not EGR3) and ((JUN_FOSNFAT1_c_4_1act_nucleus_c_Jun_2O_NFAT1_1O_7O_2s_1act_nucleus_FOS_1O_1O or JUN_FOSNFAT1_c_4_1act_nucleus_c_Jun_2O_NFAT4_1act_nucleus_FOS_1O_1O) or JUN_FOSNFAT1_c_4_1act_nucleus_c_Jun_2O_NFATc_1act_nucleus_FOS_1O_1O)) grey grey red red red grey grey blue _h_4765 PP2A_Heterotrimer_1act grey grey grey _h_4472 blue macroH2A_nucleus blue _h_3917 ATF2_JUN_ER_alpha_1act_nucleus grey grey red grey grey blue _h_4338 (AR_T_DHT_nucleus or RANBP9) red _h_657_2 blue CTGF and TGFBR2__dimer__1act_integral_to_membrane and betaglycan__dimer__integral_to_membrane_v2 _h_657_1 blue ((CTGF and TGFB1__dimer__1act_extracellular_region) and TGFBR2__dimer__1act_integral_to_membrane) red blue _h_3781 Gamma_Secretase_plasma_membrane_v1 grey grey _h_5819 blue Laminin_8_basement_membrane _h_976 blue (GTP_v1 and ((ARNO_beta_Arrestin1_2_plasma_membrane_ARNO_1act_beta_Arrestin1 or ARNO_beta_Arrestin1_2_plasma_membrane_beta_Arrestin2_ARNO_1act) or beta_2_adrenergic_receptor_1act_integral_to_membrane)) grey grey _h_4334 blue Aurora_A grey blue _h_1565 TBP_nucleus and not cortisol_GR_alpha__monomer__nucleus grey grey _h_3780 blue FZD8_integral_to_membrane and PRR and WNT3A_2N_1S_1O_extracellular_region and vacuolar_proton_transporting_V_type_ATPase_complex_1act red blue _h_5899_71 ErbB2_ErbB3_neuregulin_1_beta_1act_integral_to_membrane_v1 grey grey red blue _h_2426 ATF2_BRCA1_Oct_1_Neurofibromin_1act grey blue _h_5051_47 (RAS_family_GTP_1act_plasma_membrane_H_RAS_isoform_1_GTP_v1 or RAS_family_GTP_1act_plasma_membrane_N_RAS_GTP_v1) grey grey grey grey grey _h_5810 blue GIT1_betaPIX_PAK1_centrosome grey blue _h_4471 VEGFR1_homodimer_VEGFB_homodimer_1act_plasma_membrane red grey red grey grey blue _h_2259 STAT3__dimer___1act_nucleus blue _h_2254 (ETS1 or HIF2A_ARNT_nucleus_v3) blue _h_2255 Plasmin_1act blue _h_5899_78 ErbB2_ErbB3_neuregulin_1_beta_1act_integral_to_membrane_v1 blue _h_2250 TAp73a__tetramer__nucleus_v3 blue _h_2251 HGF_dimer__MET_dimer__GAB1_CRKL_1act_integral_to_membrane blue _h_2253 NLK_1p_nucleus blue _h_4366 Erk1_1O_1act_1O_nucleus or Erk2_1O_1O_1act_nucleus blue _h_1036_16 Arf6_GTP_1act or Arf6_GTP_1act_plasma_membrane _h_4364 blue Laminin_Alpha and Syndecan_2 _h_1788 blue Tie2_Ang1_1act blue _h_4362 ITCH or WWP1 _h_4363 blue Osteopontin _h_4360 blue CD40_JAK3_integral_to_membrane blue _h_1036_17 Arf6_GTP_1act or Arf6_GTP_1act_plasma_membrane blue _h_1783 p53__tetramer__nucleus_v2 blue _h_1782 p38_alpha_1O_1O_1act_v2 or p38_beta_1O_1O_1act _h_1781 blue alphav_beta3_Integrin red red blue _h_1786 Gamma_Secretase_plasma_membrane_v1 blue _h_1785 RPA_ATR_ATRIP_RAD17_RFC2_5_9_1_1_TopBP1_1act_nucleus _h_4369 blue FANCD2_FANCI_chromatin and PALB2 red blue _h_1702 LEF1_beta_catenin_1act_nucleus_v1 grey red _h_371 blue Plexin_D1_integral_to_membrane red _h_3120 blue Vitronectin_extracellular_region grey blue _h_2784 IGF_1R_heterotetramer_IGF1_IRS1_GRB2_Sos_Shc_RACK1_caveola blue _h_2785 SIRT1 grey grey blue _h_2780 FAK_Src_Yes_Fyn_p130_CAS_CRK_1act_focal_adhesion_Crk_Fyn_1O_1act_p130Cas_1O_FAK_6O_1act or FAK_Src_Yes_Fyn_p130_CAS_CRK_1act_focal_adhesion_Src_1act_1O_Crk_p130Cas_1O_FAK_6O_1act grey blue _h_4477 ( not HES1_nucleus) grey red blue _h_1036_11 Arf6_GTP_1act or Arf6_GTP_1act_plasma_membrane blue _h_2788 FAK_Src_Yes_Fyn_1act_focal_adhesion_v2_Fyn_1O_1act_FAK_6O_1act or FAK_Src_Yes_Fyn_1act_focal_adhesion_v2_Src_1act_1O_FAK_6O_1act _h_2789 blue iC3b red blue _h_2079 PRL_1 red red blue _h_2071 Akt1_1O_1O_1act_plasma_membrane or E2_ER_beta__dimer__1act_caveola or ER_alpha_Gai_GDP_Gbeta_gamma_1act_plasma_membrane grey _h_2074 blue RAC1_GTP_1act_cell_cell_junction red blue _h_2076 (Fra1_JUNB_1act_nucleus and ( not Fra1_FIAT_1act_nucleus)) red _h_4091 blue MYC and TAp73a__tetramer__nucleus_v3 _h_4092 blue CBL_1act_cytoplasm _h_4093 blue alpha9_beta1_Integrin_Tenascin_C_integral_to_membrane_v1 _h_4094 blue PI_4_5_P2 grey blue _h_4097 not MYC_Max_nucleus_v4 blue _h_4098 p90S6K_2O_4O_1act _h_4099 blue Sema3c_extracellular_region red red blue _h_5551 Myb_nucleus blue _h_1564 HIF1A_ARNT_nucleus _h_4712 blue IGF_1R_heterotetramer_IGF1_IRS1_caveola_v2 and p130Cas and paxillin blue _h_5051_67 (RAS_family_GTP_1act_plasma_membrane_H_RAS_isoform_1_GTP_v1 or RAS_family_GTP_1act_plasma_membrane_N_RAS_GTP_v1) blue _h_1036_18 Arf6_GTP_1act or Arf6_GTP_1act_plasma_membrane grey blue _h_6031 HIF2A_ARNT_nucleus_v3 grey red red red grey red grey grey grey _h_4475 blue E2_ERA__dimer__1act_nucleus blue _h_3142 ((Gi_family_GTP_1act or SMO_beta_Arrestin2_1act_clathrin_coat_of_coated_pit) and ( not (GLI3R_1ina or Su_fu__SIN3_HDAC_complex_nucleus))) blue _h_2883_1 RAC1_GTP_1act_plasma_membrane blue _h_2883_2 RAC1_GTP_1act_plasma_membrane grey grey red grey grey grey grey red grey grey blue _h_1824 TAp73b__tetramer__nucleus red blue _h_3146 DCC_NCK1_netrin_1_PAK1_1act_integral_to_membrane grey red grey _h_3145 blue EGFR_EGFR_EGF_EGF_p52_SHC_1act_endosome grey _h_3841 blue PKA_1act grey blue _h_2944_27 not E_cadherin_cytoplasm and (MAPK_14 or p120ctn) _h_5037_1 blue GUCA1B_1act _h_5037_3 blue GC2 _h_5037_2 blue GC2 grey grey grey red grey grey _h_3149 blue GMCSF_GMR_alpha_CSF2RB_JAK2__dimer__YWHAZ_1act_integral_to_membrane grey red red _h_5416 blue BCL2 and Calcineurin_A_alpha_beta_B1 red blue _h_5414 DVL1_1act_cytoplasm and not NAKED grey blue _h_5412 p53__tetramer__nucleus_v2 red grey red blue _h_5419 (HIF1A_ARNT_Cbp_p300_HDAC7_nucleus_HIF1A_HDAC7a_ARNT_CBP or HIF1A_ARNT_Cbp_p300_HDAC7_nucleus_HIF1A_HDAC7a_ARNT_p300) blue _h_5418 (( not PKC_theta_1act_plasma_membrane) and ((NFAT1_c_4__dimer__EGR4_NFAT1_1O_7O_2s_1act_nucleus_EGR4_nucleus or NFAT1_c_4__dimer__EGR4_NFAT4_1act_nucleus_EGR4_nucleus) or NFAT1_c_4__dimer__EGR4_NFATc_1act_nucleus_EGR4_nucleus)) blue _h_1255 ( not JUNB_nucleus) _h_1526 blue alpha3_beta1_Integrin_integral_to_membrane blue _h_1257 PI_3_4_5_P3_plasma_membrane _h_1256 blue ER_alpha_nucleus _h_6203 blue CDC42_GTP_IRSP53_1act grey _h_1253 blue EGFR red grey blue _h_2760_5 CK1_alpha or CK1_epsilon grey _h_4076_3 blue (FOXO4_14_3_3_family_nucleus_YWHAG_FOXO4_1O_2O and Ran_GTP_Exportin_1) blue _h_1258 GM1_plasma_membrane blue _h_1528 IKKs_1act and not PKC_zeta_PAR4 grey grey grey grey blue _h_2944_25 not E_cadherin_cytoplasm and (MAPK_14 or p120ctn) red grey grey grey grey grey red blue _h_6378 IRSP53 or PI_3_4_5_P3_plasma_membrane or RAC1_GTP_1act_plasma_membrane grey grey grey blue _h_4194_2 PI_3_4_P2_plasma_membrane _h_5579 blue PIK3R1 and SHIP grey blue _h_5751 Exportin_1_RanGTP_nucleus blue _h_5574 Caveolin_1 blue _h_2944_22 not E_cadherin_cytoplasm and (MAPK_14 or p120ctn) _h_5576 blue beta_catenin_nucleus grey blue _h_5570 ( not JUN_FOS_1act_nucleus_v4) _h_5752 blue CHK1 grey blue _h_5573 TAp73b__tetramer__nucleus grey red grey blue _h_3465 Src_1act_1O grey red red grey _h_4937 blue TIF2 grey blue _h_5757 NGF__dimer__p75_NTR__1act_integral_to_membrane blue _h_5653 E2_ERA__dimer__Src_1_1act_nucleus red grey red grey grey red _h_5460_3 blue LPA_LPA1 _h_5460_2 blue LPA_LPA1 blue _h_5051_1 (RAS_family_GTP_1act_plasma_membrane_H_RAS_isoform_1_GTP_v1 or RAS_family_GTP_1act_plasma_membrane_N_RAS_GTP_v1) red red red grey grey grey blue _h_927 JNK2_1O_1O_1act grey grey _h_341 blue (GTP_v1 and ((ARF6_GDP_1ina_plasma_membrane_v1 or ARNO_1act_plasma_membrane) or PI_4_5_P2_plasma_membrane)) _h_340 blue Syndecan_1 _h_343 blue G12 and S1P5 grey blue _h_344 Akt1_1O_1act_1O_1O_plasma_membrane grey grey blue _h_349 IQGAP1 or RAS_family_GTP_1act_plasma_membrane_H_RAS_isoform_1_GTP_v1 or RAS_family_GTP_1act_plasma_membrane_N_RAS_GTP_v1 blue _h_348 Akt1_1O_1act_1O_1O_plasma_membrane grey grey grey grey red grey grey red grey grey red red grey grey blue _h_5051_3 (RAS_family_GTP_1act_plasma_membrane_H_RAS_isoform_1_GTP_v1 or RAS_family_GTP_1act_plasma_membrane_N_RAS_GTP_v1) red red grey grey grey red red red grey grey red blue _h_4959 ((JUN_FOSNFAT1_c_4_1act_nucleus_c_Jun_2O_NFAT1_1O_7O_2s_1act_nucleus_FOS_1O_1O or JUN_FOSNFAT1_c_4_1act_nucleus_c_Jun_2O_NFAT4_1act_nucleus_FOS_1O_1O) or JUN_FOSNFAT1_c_4_1act_nucleus_c_Jun_2O_NFATc_1act_nucleus_FOS_1O_1O) _h_4958 blue PINCH1 and beta_parvin red grey grey _h_4952 blue CYR61_extracellular_region blue _h_4955 LKB1_ER_alpha_nucleus red _h_4957 blue GRB2 blue _h_4956 ITCH_endosome red grey blue _h_793 (RBPJ_NICD_MAML1_2_p300_1act_nucleus and ( not HES1_nucleus)) _h_580 blue SMO_beta_Arrestin2_1act_clathrin_coat_of_coated_pit or hFu grey grey grey grey red red grey grey blue _h_4343_2 GMCSF_GMR_alpha_CSF2RB_JAK2__dodecamer__1act_integral_to_membrane_v1 grey red grey red grey grey red grey _h_3003_1 blue p38alpha_beta_MAPKAPK2_1act_MAPKAPK2_4O_1O_p38_alpha_1O_1O_1act_v2 red _h_3991_2 blue FAK_Src_Yes_Fyn_RasGAP_1act_cell_leading_edge_Fyn_1O_1act_FAK_6O_1act_RasGAP red grey grey grey grey red blue _h_438 ((STAT5A_B__dimer__1act_nucleus or STAT5A__dimer__active_1act_nucleus_v2) or STAT5B__dimer__1act_nucleus) grey grey red blue _h_515_1 (IL2_IL2R_alpha_beta_gamma_JAK1_LCK_JAK3_1act_integral_to_membrane or IL4_IL4R_JAK1_IL2R_gamma_JAK3_1act_integral_to_membrane) and not (IL2R_beta_JAK1_LCK_SOCS1_1act_integral_to_membrane or IL2R_beta_JAK1_LCK_SOCS3_1act_integral_to_membrane) red _h_859 blue NEDD8_1act and (FBXO11 or MDM2) red grey grey grey grey grey grey red grey grey _h_238_7 blue alpha6_beta1_Integrin grey red grey _h_4264_2 blue Erk1_1O_1act_1O_nucleus _h_3131_3 blue Src_1act and netrin_1_DCC_UNC5C_1act_integral_to_membrane red grey grey grey red grey red grey grey _h_2221 blue YY1_nucleus _h_434 blue Ku_Artemis_DNA_PKcs__dimer__Pol_Mu_XRCC4__dimer__Ligase_IV_site_of_double_strand_break_v2 red grey grey red blue _h_212 (AR_T_DHT_nucleus or JMJD2C) red _h_3026_1 blue Ephrin_B3_integral_to_membrane grey _h_210 blue LIP1_cytoplasm and SMAD4 _h_5891 blue PLK1_1O_1act _h_238_5 blue alpha6_beta1_Integrin _h_2575_2 blue Fyn and NCK1_2_PAK2_NCK2_PAK2 grey grey _h_741 blue RXRs_NUR77_nucleus and not 9cRA red red red red grey grey red grey grey red red blue _h_219 STAT5A_B__dimer__1act_nucleus or STAT5A__dimer__active_1act_nucleus_v2 or STAT5B__dimer__1act_nucleus blue _h_2441 Caspase_6_1act or Caspase_8_1act _h_2440 blue CBL_5O_1act_cytoplasm grey _h_2442 blue GNB1_GNGT1 blue _h_2445 ((STAT5A_B__dimer__1act_nucleus or STAT5A__dimer__active_1act_nucleus_v2) or STAT5B__dimer__1act_nucleus) blue _h_2444 E2F1_DP_nucleus_v4 and not (RB1_E2F1_3_DP_nucleus_v1_DP1_E2F1_RB1_2O or RB1_E2F1_3_DP_nucleus_v1_DP1_E2F3_RB1_2O or RB1_E2F1_3_DP_nucleus_v1_DP1_RB1_2O_E2F2) blue _h_1805 NQO1 or PML _h_2449 blue GTP_v1 and (GAB1_SHC_GRB2_SOS1_1act_v2 or SHC_Grb2_SOS1_1act_v2) grey _h_5897 blue TERT red grey red blue _h_39 FOXA1_nucleus blue _h_5051_42 (RAS_family_GTP_1act_plasma_membrane_H_RAS_isoform_1_GTP_v1 or RAS_family_GTP_1act_plasma_membrane_N_RAS_GTP_v1) blue _h_5051_43 (RAS_family_GTP_1act_plasma_membrane_H_RAS_isoform_1_GTP_v1 or RAS_family_GTP_1act_plasma_membrane_N_RAS_GTP_v1) blue _h_807_81 FASLG_FAS__trimer__Src_Syk_1act_integral_to_membrane or TRAIL__trimer__extracellular_region blue _h_807_80 FASLG_FAS__trimer__Src_Syk_1act_integral_to_membrane or TRAIL__trimer__extracellular_region blue _h_5051_46 (RAS_family_GTP_1act_plasma_membrane_H_RAS_isoform_1_GTP_v1 or RAS_family_GTP_1act_plasma_membrane_N_RAS_GTP_v1) grey blue _h_5051_44 (RAS_family_GTP_1act_plasma_membrane_H_RAS_isoform_1_GTP_v1 or RAS_family_GTP_1act_plasma_membrane_N_RAS_GTP_v1) red blue _h_1063 E2_ERA__dimer__AIB1_1act_nucleus blue _h_5051_48 (RAS_family_GTP_1act_plasma_membrane_H_RAS_isoform_1_GTP_v1 or RAS_family_GTP_1act_plasma_membrane_N_RAS_GTP_v1) red blue _h_1066 PDK1_1O blue _h_1067 Arf6_GTP_1act_plasma_membrane or Phosphatidic_acid _h_1064 blue IHH_N_PTCH1_integral_to_membrane or SHH_Np_Cholesterol_PTCH1_integral_to_membrane grey grey grey grey grey grey red _h_3179 blue EGFR_integral_to_membrane and NRG1_extracellular_region grey grey grey grey blue _h_2782 (JUN_JUN_FOS_1act_nucleus_v1_FOS_JUN_2O_2O or JUN_JUN_FOS_1act_nucleus_v1_JUN_JUN_2O_2O) blue _h_30 (SMAD2_3_SMAD4_FOXO1_3a_4_CEBPB_1act_nucleus_CEBPB_FOXO1_3a_4_1act_Smad3_2O_1act_SMAD4 or SMAD2_3_SMAD4_FOXO1_3a_4_CEBPB_1act_nucleus_CEBPB_SMAD2_2O_1act_FOXO1_3a_4_1act_SMAD4) _h_1996 blue CK2 or MAPK_14 blue _h_3543 HDAC1_1act_nucleus grey red blue _h_32 AP1_1act_nucleus or CEBPB or STAT3__dimer___1act_nucleus red grey red red blue _h_2292 Fra1_JUNB_1act_nucleus grey grey blue _h_1673 E2_ERA_nucleus or FOXA1_nucleus grey _h_3170 blue PI3K red grey grey red red _h_3094 blue DKK2 and LRP6 and Non_canonical_Wnts grey grey grey grey grey grey blue _h_3541 E2_ERA__dimer__1act_nucleus _h_3171 blue NUMB _h_3096 blue Src_1act_1O _h_3233 blue PTCH1_integral_to_membrane _h_4178_1 blue G13_GTP_1act_cytoplasm and GTP_v1 grey red red grey grey _h_3098 blue Ca2__cytoplasm and FKBP12_FK506 red red red blue _h_4558 IL23_IL23R_JAK2_TYK2_1act_integral_to_membrane blue _h_2944_30 not E_cadherin_cytoplasm and (MAPK_14 or p120ctn) grey _h_4139 blue LRP6_integral_to_membrane and WNT7A_extracellular_region blue _h_4138 Arf6_GTP_1act_plasma_membrane or Ca2__v1 red blue _h_3540 Ca2__cytoplasm or DAG_v2 blue _h_3176 p53__tetramer__nucleus_v2 _h_4132 blue p70S6K_3O_4O _h_4131 blue Nrp1 and VEGFR1_integral_to_membrane blue _h_2944_32 not E_cadherin_cytoplasm and (MAPK_14 or p120ctn) blue _h_4137 p38alpha_beta_MAPKAPK2_1act_MAPKAPK2_4O_1O_p38_alpha_1O_1O_1act_v2 or p38alpha_beta_MAPKAPK2_1act_MAPKAPK2_4O_1O_p38_beta_1O_1O_1act _h_4135 blue GTP_v1 and RhoA_GDP_RHOGDI_1ina blue _h_4134 Fra2_JUND_1act_nucleus_v2 blue _h_4116 (Fra1_JUN_1act_nucleus and ( not Fra1_FIAT_1act_nucleus)) grey grey grey red red grey grey red blue _h_4110 (p38_alpha_1O_1O_1act_v2 or p38_beta_1O_1O_1act) blue _h_2863 MYC_Max_nucleus_v2 _h_2862 blue ErbB2_integral_to_membrane and neuregulin_4_extracellular_region grey _h_2860 blue DAP3_GTP _h_2867 blue RET9_GFRalpha1_GDNF_membrane_raft blue _h_2866 TAp73b__tetramer__nucleus grey grey red _h_2869 blue TCF4_beta_catenin_1act_nucleus red blue _h_2944_38 not E_cadherin_cytoplasm and (MAPK_14 or p120ctn) grey _h_2276 blue SOCS1 grey _h_699 blue TRAIL_TRAILR1_integral_to_membrane blue _h_676 Aurora_A grey grey _h_3646 blue HDAC3_nucleus grey blue _h_6232 Zn2_ red grey grey red red red _h_1523_1 blue Jnk1_1O_1act_1O or p38_alpha_1O_1O_1act_v2 grey blue _h_3641 BoNT_C1_Light_Chain_1act_cytoplasm red grey grey _h_4509_2 blue NT3__dimer__TRKC_1act_integral_to_membrane and Tiam1 grey red grey blue _h_6233 HIF2A_ARNT_nucleus_v3 _h_1523_2 blue Jnk1_1O_1act_1O or p38_alpha_1O_1O_1act_v2 red blue _h_3964_4 SDF1_CXCR4_JAK2_1act_integral_to_membrane blue _h_3964_2 SDF1_CXCR4_JAK2_1act_integral_to_membrane blue _h_3964_3 SDF1_CXCR4_JAK2_1act_integral_to_membrane blue _h_3964_1 SDF1_CXCR4_JAK2_1act_integral_to_membrane _h_5686 blue AR_T_DHT_nucleus _h_488 blue PKC_zeta and p62 _h_4549 blue EPHA4_integral_to_membrane blue _h_4554 SMAD3_SMAD4_SP1_3_1act_nucleus grey blue _h_4542 not Antigen_IgE_Fc_epsilon_R1_LYN_SYK_v2 and (Btk_1act_2O_plasma_membrane or Jnk1_1O_1act_1O) blue _h_483 IL12_IL12R_TYK2_JAK2_1act_integral_to_membrane _h_4541 blue HDAC4_nucleus and (HDAC4_HDAC3_SMRT__N_CoR2__nucleus or HDAC4_Ubc9_nucleus) blue _h_4546 (AR_T_DHT_nucleus and ( not TCF4E_v1)) _h_487 blue Arf6_GTP_1act blue _h_484 (E2F1_DP_nucleus_v4 or SP1) grey blue _h_4085_1 Lethal_Factor_cytoplasm grey _h_5428 blue ATM_1act and M_R_N_Complex blue _h_1733 not PKC_zeta_ceramide grey blue _h_5995 TAp73a__tetramer__nucleus_v3 red red blue _h_5683 (E2_ERB__dimer__1act_nucleus and ( not E2_ERB__dimer__DP97_1act_nucleus)) blue _h_807_29 FASLG_FAS__trimer__Src_Syk_1act_integral_to_membrane or TRAIL__trimer__extracellular_region blue _h_4218 SMAD3_SMAD4_GATA3_1act_nucleus red blue _h_5427 Gab1_1O_1act_cytoplasm grey blue _h_154 TAK1_TAB_family_nucleus_TAB1_TAK1_1act or TAK1_TAB_family_nucleus_TAB2_TAK1_1act _h_155 blue uPA _h_624 blue CBL_1O_1act_cytoplasm grey blue _h_622 E2_ERA__dimer__PCNA_1act_nucleus grey grey grey red blue _h_4889 HDAC3_SMRT__N_CoR2__nucleus or NCoR2 or TNF_alpha_TNFR1A _h_628 blue FAS_FADD_DAXX_Ask1_Caspase_8_Caspase_8 _h_629 blue Vitronectin_extracellular_region grey blue _h_4888 MYC_Max_nucleus_v2 grey blue _h_5070 SENP1 blue _h_5073 FGFR3_FGF_complex_Pyk2 red red grey blue _h_5072 sTNF_alpha_TNFR1A_TRADD_RIP_TRAF2_p62_Atypical_PKCs_1act_integral_to_membrane grey grey red grey _h_3605 blue WNT5A_4p_1S_4p_extracellular_region and (LRP6_integral_to_membrane or WNT3A_2N_1S_1O_extracellular_region) blue _h_4551 STAT3__dimer___1act_nucleus red _h_511_1 blue sTNF_alpha_TNFR1A_TRADD_RIP_TRAF2_1act_integral_to_membrane red red red grey red red blue _h_2540 EGF_EGFR_1act grey blue _h_1518 (((E2F1_3_DP_nucleus_DP1_E2F1 or E2F1_3_DP_nucleus_DP1_E2F2) or E2F1_3_DP_nucleus_DP1_E2F3) and ( not (((PRMT5 or RB1_E2F1_3_DP_HDAC1_RBBP4_nucleus_HDAC1_DP1_E2F1_RBBP4_RB1) or RB1_E2F1_3_DP_HDAC1_RBBP4_nucleus_HDAC1_DP1_E2F3_RBBP4_RB1) or RB1_E2F1_3_DP_HDAC1_RBBP4_nucleus_HDAC1_DP1_RBBP4_RB1_E2F2))) grey grey _h_1519 blue VEGFR1_integral_to_membrane and VEGFR2_integral_to_membrane red blue _h_6236 Erk2_1O_1O_1act blue _h_2543 Erk1_1O_1act_1O_nucleus or Erk2_1O_1O_1act_nucleus red grey _h_1517 blue Kininogen grey blue _h_1885 LKB1_MO25_STRADA_STRADB_cytoplasm_v2 red blue _h_5899_70 ErbB2_ErbB3_neuregulin_1_beta_1act_integral_to_membrane_v1 blue _h_1880 (RBPJ_NICD_MAML1_2_p300_1act_nucleus and ( not TWIST1_nucleus)) blue _h_1881 (( not POU4F1_nucleus) and ((ASPP or SP1_3_nucleus) or p53__tetramer__nucleus_v10)) blue _h_1882 CSK_PAG1_1act blue _h_1883 (AR_T_DHT_nucleus and ( not PIASy)) blue _h_3018 (TNF_alpha_TNFR1A_FAN or TNF_alpha_TNFR1A_TRADD_MADD_cIAP2_RIP_TRAF2_RAIDD) blue _h_6235 Fra1_JUN_1act_nucleus red grey red red grey grey red red grey _h_3017 blue GNB1_GNG2_1act_cytoplasm blue _h_1513 Aurora_B _h_2548 blue VEGFR3_VEGFD_1act_plasma_membrane blue _h_3355 not CDC42_GDP_1ina_plasma_membrane grey grey blue _h_2549 HRAS_GTP_1act_v2 red red _h_5355_2 blue FAK_Src_Yes_Fyn_1act_focal_adhesion_v2_Src_1act_1O_FAK_6O_1act and m_calpain blue _h_1943 Elf1 or NERF2 grey _h_5355_1 blue Erk2_1O_1O_1act and m_calpain grey grey grey red red _h_4455 blue LAT_GRAP2_SLP76_VAV1_1act_integral_to_membrane blue _h_1947 ((NFAT1_c_4_MAF_IRF4_MAF_nucleus_NFAT1_1O_7O_2s_1act_nucleus_IRF4_nucleus or NFAT1_c_4_MAF_IRF4_MAF_nucleus_NFATc_1act_nucleus_IRF4_nucleus) or NFAT1_c_4_MAF_IRF4_NFAT4_1act_nucleus_MAF_nucleus_IRF4_nucleus) grey grey red _h_1946 blue Telomerase blue _h_2848 CD40_CD40L__trimer__JAK3__trimer__integral_to_membrane blue _h_6025 not Bam32_1O_1act and (Calcineurin_1act or VAV2_1act_1O) grey grey _h_6484 blue p130Cas_1O _h_6306_1 blue EPHB1_integral_to_membrane _h_3359 blue APS_homodimer and CBL_cytoplasm and Insulin_Receptor_Insulin_IRS1_membrane_raft red grey red grey red grey red grey red red grey _h_2843 blue HGF_dimer__MET_dimer__1act_integral_to_membrane_v1 red grey grey _h_2277 blue AR_nucleus grey red _h_2272 blue Ca2__extracellular_region _h_2273 blue VEGFR2_integral_to_membrane blue _h_2270 Digestive_enzymes_endosome blue _h_2271 E2F1_DP_nucleus_v4 or SP1 blue _h_1806 DAG_v2 _h_4561_2 blue ((MAML1_2 and RBPJ_NCoR_HDAC1_nucleus_HDAC1_RBPSUH_SMRT__N_CoR2_) and p300_nucleus) grey _h_4458 blue Akt1_1O_1act_plasma_membrane_v2 and p21CIP1_nucleus _h_4561_1 blue ((MAML1_2 and RBPJ_NCoR_HDAC1_nucleus_HDAC1_RBPSUH_NCoR2) and p300_nucleus) grey blue _h_3897 Neurl1_1N red _h_3896 blue BMP9__dimer__extracellular_region and BMPR2__homodimer__integral_to_membrane and CK2B_FKBP12_ALK1__dimer__1ina_integral_to_membrane grey _h_3906 blue C3G_1act_cell_leading_edge and RAP1_GDP_1ina_cell_leading_edge _h_4302 blue Hsp90 and Telomerase_catalytic_core_complex and p23 blue _h_4404 BUB1 blue _h_3903 HIF1A_ARNT_nucleus blue _h_4305 TAp63g__tetramer__1act_nucleus_v2 grey _h_4307 blue DP97 blue _h_4308 TAp73a__tetramer__nucleus_v3 _h_4403 blue GRB2_SOS1_v2 red grey red grey blue _h_1903_1 ((GMCSF_GMR_alpha_CSF2RB_JAK2__dodecamer__1act_integral_to_membrane_v1 or IL3_IL3RA_CSF2RB__dodecamer__JAK2_JAK2_1act_integral_to_membrane_v3) or IL5_IL5RA_CSF2RB__hexamer__JAK2_JAK2_1act_clathrin_coated_vesicle_v1) blue _h_4400 PIP5K1C_AP1M1 red _h_5386 blue NF_kappa_B1_p50_RelA_I_kappa_B_alpha_cytoplasm_v2 grey grey red _h_2051 blue SMAD2_cytoplasm blue _h_2056 (POU4F1_nucleus and ( not p53__tetramer__nucleus_v2)) blue _h_2057 LEF1_beta_catenin_1act_nucleus_v1 blue _h_2054 mTORC1_1act _h_2055 blue BRM red blue _h_2059 (T_DHT_AR_TIP60_nucleus and ( not (HDAC1_2s or MDM2))) red red red grey grey _h_5389 blue p62DOK grey _h_1801 blue RHOA_GTP_1act _h_2764 blue VEGFR1_integral_to_membrane grey blue _h_5999 RAP1_GTP_1act_cell_leading_edge blue _h_5899_12 ErbB2_ErbB3_neuregulin_1_beta_1act_integral_to_membrane_v1 grey red blue _h_1043_5 not SLAP and (CSK_1act_plasma_membrane or PDGF_BB_PDGFRB__dimer__1act_integral_to_membrane_v1) red _h_1802 blue Tenascin_C_extracellular_matrix red red red grey grey grey grey blue _h_6197 LEF1_beta_catenin_PITX2_1act_nucleus blue _h_6196 TCF3_beta_catenin_TERT_BRG1_1act_nucleus blue _h_6195 2_AG_growth_cone grey red blue _h_6192 ( not dNp63a__tetramer__nucleus_v2) red red grey _h_1803 blue HGF_dimer__MET_dimer__1act_integral_to_membrane_v1 grey red red grey blue _h_1494 (NF_kappa_B1_p50_RelA and ( not cortisol_GR_alpha__monomer__nucleus)) _h_6477 blue IL2R_beta_JAK1_Fyn_integral_to_membrane and IL2_1O_extracellular_region blue _h_5674 ((((((PKC_beta_1act_plasma_membrane or PKC_delta_1act_plasma_membrane) or PKC_epsilon_1act_plasma_membrane) or PKC_isoenzymes_1act_plasma_membrane) or PKC_theta_1act_plasma_membrane) or PRKCG_1act_plasma_membrane) or PRKCH_1act_plasma_membrane) blue _h_3658 p53__tetramer__nucleus_v2 _h_3657 blue IL2_extracellular_region and TCR_CD3_MHC_I_CD8_1act_integral_to_membrane blue _h_3656 not MYC_Max_MIZ_1_nucleus blue _h_3655 p53__tetramer__nucleus_v2 _h_3653 blue PTP1B_1O_1act_plasma_membrane _h_3652 blue PAK2_1act blue _h_3651 E2_ERA__dimer__POU4F2_1act_nucleus and not E2_ERA__dimer__POU4F1_1act_nucleus red red blue _h_5433 Myb_nucleus and not (Fog1_nucleus or GATA1_nucleus) red blue _h_5435 (B7_family_CD28_1act_integral_to_membrane_v2 or TCR_CD3_MHC_I_CD8_1act_integral_to_membrane) grey _h_5437 blue NICD_nucleus grey blue _h_5439 Akt1_1O_1act_1O_1O_plasma_membrane blue _h_5438 ((((((((((ASK1_1act or CDC42_GTP_1act) or CaM_Ca2__CAMKIIB_ASK1_1act) or MEKK1_2O_1act) or MLK2_1act) or TAK1_TAB_family_1act_v1_TAB1_TAK1_1act) or TAK1_TAB_family_1act_v1_TAB2_TAK1_1act) or TAO_family_active_1act) or TRAF2_ASK1_1act) or TRAF6_ASK1_1act) or sTNF_alpha_TNFR1A_TRADD_RIP_TRAF2_1act_endosome) _h_5522 blue Akt1_1O_1act_plasma_membrane_v2 blue _h_1290 Erk2_1O_1O_1act red blue _h_1789_1 WNT1_extracellular_region blue _h_2434_11 ((EGFR_EGFR_1act_integral_to_membrane_v1 or EGFR_EGFR_EGF_EGF_GRB2_GAB1_1act_integral_to_membrane_v1) and ( not (EGFR_EGFR_1ina_integral_to_membrane or EGFR_EGFR_EGF_EGF_GRB2_GAB1_1ina_integral_to_membrane))) blue _h_6057 JUN_FOS_1act_nucleus_v4 _h_1505 blue GRB2_SOS1_cytoplasm grey grey grey blue _h_6228 SHP1_1act_2O red red grey grey grey blue _h_1789_2 WNT1_extracellular_region grey red red _h_5556 blue EGFR_integral_to_membrane blue _h_5557 (T_DHT_AR_TIF2_CARM1_nucleus and ( not CEBPA)) red red blue _h_353_2 PKC_zeta_1act or WNT5A_FZD2_ROR2_dimer__FLNA_1act_integral_to_membrane _h_3654_7 blue Btk_plasma_membrane red grey red _h_1400_2 blue STAT1__dimer__1act_nucleus_v4 _h_1400_1 blue CBP_nucleus grey grey grey grey red red red _h_2194 blue 9cRA and RXR_alpha grey blue _h_3314 TGFB_TGFBR2_TGFBR1_PML_SARA_SMAD2_3_AP2B2_1act_early_endosome_v2 and not TGFB_TGFBR2_TGFBR1_STRAP_SMAD7_1act_integral_to_membrane blue _h_5881 Insulin_Receptor_Insulin_v2 blue _h_5882 (TIF1A or T_DHT_AR_TIF2_nucleus_v1) _h_5883 blue Fra1_1O_2O_nucleus and JUNB_nucleus and JUND_nucleus and SP1 blue _h_5884 TAp73b__tetramer__nucleus red grey blue _h_5887 JUN_JUN_FOS_1act_nucleus_v1_FOS_JUN_2O_2O or JUN_JUN_FOS_1act_nucleus_v1_JUN_JUN_2O_2O _h_5888 blue SIRT2_cytoplasm grey _h_5737 blue GMCSF_GMR_alpha_CSF2RB_JAK2__dodecamer__SHC_1act_integral_to_membrane grey red blue _h_2998_1 ((((((BRAF_1O_1act_cytoplasm or CXCL4_CXCR3_B_integral_to_membrane) or CXCL9_11_CXCR3_B_integral_to_membrane) or GADD45B_1act) or GADD45G_1act) or PAK1_1O_1O_1act) or PKN_1act) blue _h_2998_2 ((((((BRAF_1O_1act_cytoplasm or CXCL4_CXCR3_B_integral_to_membrane) or CXCL9_11_CXCR3_B_integral_to_membrane) or GADD45B_1act) or GADD45G_1act) or PAK1_1O_1O_1act) or PKN_1act) grey _h_2029 blue (PDK1_1act_plasma_membrane and TGFB_TGFBR2_TGFBR1_STRAP_1act_integral_to_membrane) grey red red grey red blue _h_1809 ATF2_JUND_1act_nucleus blue _h_819 (AR_T_DHT_nucleus and ( not TR2)) red grey _h_363 blue sTNF_alpha_TNFR1A_TRADD_TRAF2_1act_endosome blue _h_814 CBP or SIRT1 or p300 _h_361 blue IGF_1R_heterotetramer_IGF1_IRS1 _h_360 blue SRF__dimer__Myocardin_1act_nucleus _h_811 blue SIRT1_nucleus grey blue _h_813 LKB1_MO25_STRADA_STRADB_cytoplasm_v2 grey blue _h_1293 Digestive_enzymes_endosome grey grey red grey grey _h_3211_2 blue Vinculin grey blue _h_2227 not (Ang1 or Thrombin_extracellular_region) and (Angiotensin_II_AGTR1 or ETS1 or FGF2 or FOXO1) blue _h_4685 (ILK_1act or PI3K_1act_v1) _h_4932 blue KU_site_of_double_strand_break _h_4931 blue ADAM2 blue _h_4930 Gq_family_GTP_1act or Nephrin_NEPH1_podocin_Cholesterol_membrane_raft _h_4681 blue RPA_ATR_ATRIP_1act_nucleus blue _h_4936 RBPJ_NICD_1act_nucleus and not SHARP_RBPJ_CtIP_CtBP_LSD1_nucleus grey blue _h_4682 (( not Pyk2) and (ARA55 or AR_T_DHT_nucleus)) grey _h_4939 blue CBL_5O_1act_cytoplasm blue _h_4938 Ca2__cytoplasm or DAG_v2 blue _h_4689 FOXM1B_nucleus _h_1700 blue Histone_H1b_1a_1act_1N red _h_1830_1 blue Fyn_cytoplasm grey red red grey grey grey grey _h_4596_1 blue CABIN1 and MEF2D_1act_nucleus and p300_nucleus _h_2001 blue PI4_Kinase and (Vitronectin or alphav_beta3_Integrin) red grey red grey grey red _h_1823_1 blue CK2 and uPA_uPAR_alphav_beta3_Integrin_Vitronectin_1act_integral_to_membrane blue _h_1036_89 Arf6_GTP_1act or Arf6_GTP_1act_plasma_membrane grey blue _h_4632 p53__tetramer__nucleus_v2 red blue _h_1036_84 Arf6_GTP_1act or Arf6_GTP_1act_plasma_membrane blue _h_1036_87 Arf6_GTP_1act or Arf6_GTP_1act_plasma_membrane blue _h_1036_86 Arf6_GTP_1act or Arf6_GTP_1act_plasma_membrane grey blue _h_1036_80 Arf6_GTP_1act or Arf6_GTP_1act_plasma_membrane red blue _h_1036_82 Arf6_GTP_1act or Arf6_GTP_1act_plasma_membrane grey red _h_2179 blue IL27_EBI3 red grey red grey red grey grey red grey _h_3467 blue GRB2 and RET9_GFRalpha1_GDNF_SHC_v2 grey grey grey _h_2268_1 blue FAK_Src_Yes_Fyn_p130_CAS_1act_focal_adhesion_Fyn_1O_1act_p130Cas_1O_FAK_6O_1act red red blue _h_6427 ( not (IFN_gamma_IRF1 or p27Kip1)) _h_6426 blue Ephrin_B_EPHB1_1act_integral_to_membrane grey blue _h_6424 p53__tetramer__nucleus_v2 blue _h_6423 (((JUN_FOSNFAT1_c_4_1act_nucleus_c_Jun_2O_NFAT1_1O_7O_2s_1act_nucleus_FOS_1O_1O or JUN_FOSNFAT1_c_4_1act_nucleus_c_Jun_2O_NFAT4_1act_nucleus_FOS_1O_1O) or JUN_FOSNFAT1_c_4_1act_nucleus_c_Jun_2O_NFATc_1act_nucleus_FOS_1O_1O) or Oct_1_nucleus) blue _h_6422 MEK5_1O_1O_1act grey blue _h_6420 not MYC_Max_nucleus_v4 grey grey grey blue _h_6429 Fra1_JUN_1act_nucleus blue _h_6428 BDNF__dimer__TRKB_1act_endosome_v2 or NGF__dimer__TRKA_1act_endosome or NT3__dimer__TRKC_1act_endosome or NT_4_5__dimer__TRKB_1act_endosome blue _h_2993 PDGF_BB_PDGFRB__dimer__1act_integral_to_membrane_v1 grey grey _h_5015_4 blue PPP2R1A_PPP2CA_PPP2R2A_1act red grey blue _h_717 KLRG1_SHP2 grey grey red red red red grey _h_6214 blue PRL_3 blue _h_4292 HIF1A_ARNT_nucleus red _h_5015_2 blue PPP2R1A_PPP2CA_PPP2R2A_1act grey red grey red grey grey grey grey red _h_6215 blue VEGFA_PLGF1_extracellular_region and VEGFR1_integral_to_membrane red red blue _h_715 (HES1_HES6_1act_nucleus and ( not HES1_TLE1_PARP1_1act_nucleus)) red red red blue _h_2428 HGF_dimer__MET_dimer__1act_nucleus _h_4389 blue IGF_1R_heterotetramer_IGF1 blue _h_2423 FGFR1_1act_growth_cone grey grey blue _h_2420 ((JUN_FOSNFAT1_c_4_1act_nucleus_c_Jun_2O_NFAT1_1O_7O_2s_1act_nucleus_FOS_1O_1O or JUN_FOSNFAT1_c_4_1act_nucleus_c_Jun_2O_NFAT4_1act_nucleus_FOS_1O_1O) or JUN_FOSNFAT1_c_4_1act_nucleus_c_Jun_2O_NFATc_1act_nucleus_FOS_1O_1O) _h_2427 blue VEGFA206__dimer__extracellular_region grey blue _h_2425 cIAP2_cytoplasm blue _h_2424 IL2_IL2R_alpha_beta_gamma_JAK1_LCK_JAK3_SHC_GAB2_GRB2_SOS1_SHP2_PI3K_1act_integral_to_membrane grey red red red grey red _h_5254 blue EGFR_integral_to_membrane and (Ca2__cytoplasm or ETA_receptor_Endothelin_1_integral_to_membrane) grey blue _h_5051_65 (RAS_family_GTP_1act_plasma_membrane_H_RAS_isoform_1_GTP_v1 or RAS_family_GTP_1act_plasma_membrane_N_RAS_GTP_v1) blue _h_5051_66 (RAS_family_GTP_1act_plasma_membrane_H_RAS_isoform_1_GTP_v1 or RAS_family_GTP_1act_plasma_membrane_N_RAS_GTP_v1) _h_4493_3 blue REDD1 blue _h_5051_60 (RAS_family_GTP_1act_plasma_membrane_H_RAS_isoform_1_GTP_v1 or RAS_family_GTP_1act_plasma_membrane_N_RAS_GTP_v1) blue _h_5051_61 (RAS_family_GTP_1act_plasma_membrane_H_RAS_isoform_1_GTP_v1 or RAS_family_GTP_1act_plasma_membrane_N_RAS_GTP_v1) blue _h_5051_62 (RAS_family_GTP_1act_plasma_membrane_H_RAS_isoform_1_GTP_v1 or RAS_family_GTP_1act_plasma_membrane_N_RAS_GTP_v1) grey red grey blue _h_5256 Fra2_JUNB_1act_nucleus_v1 blue _h_5051_68 (RAS_family_GTP_1act_plasma_membrane_H_RAS_isoform_1_GTP_v1 or RAS_family_GTP_1act_plasma_membrane_N_RAS_GTP_v1) red red blue _h_825 TGFB_TGFBR2_TGFBR1_PML_SARA_SMAD2_3_AP2B2_1act_early_endosome_v2 and not TGFB_TGFBR2_TGFBR1_STRAP_SMAD7_1act_integral_to_membrane red _h_4380 blue GRIT blue _h_826 FOXM1B_1O_1act_nucleus_v2 grey red grey blue _h_618 ADAM10 blue _h_4383 not MYC_Max_nucleus_v4 grey grey grey blue _h_602 Akt1_1O_1act_1O_1O_plasma_membrane grey red red grey grey _h_4306 blue TAp63g__tetramer__nucleus grey red grey grey red blue _h_6042 PIP5K1B_1act_plasma_membrane or PIP5K1C_1act_plasma_membrane grey red blue _h_807_19 FASLG_FAS__trimer__Src_Syk_1act_integral_to_membrane or TRAIL__trimer__extracellular_region red blue _h_6047 COT or MEKK1_2O_1act or TAK1_2O_1O_1act grey grey grey _h_1018 blue CNTN1_integral_to_membrane grey _h_4178_2 blue G13_GTP_1act_cytoplasm and RhoA_B_C_GDP_1ina_RhoC_GDP_v1 blue _h_4115 eEF2K grey blue _h_4117 ( not WT1) _h_2330 blue FAK_1act_1O_cytoplasm red _h_6213_1 blue CBP_nucleus and HIF2A_1h_1h_cytoplasm _h_6213_2 blue HIF2A_1h_1h_cytoplasm and p300_nucleus _h_1016 blue E_cadherin_beta_catenin_basolateral_plasma_membrane and (_alpha_2__beta_2CK2_1act or _alpha___alpha_prime___beta_2_CK2_1act or _alpha_prime_2__beta_2_CK2_1act) grey _h_4119 blue TRF2 blue _h_1015 not cortisol_GR_alpha__monomer__nucleus red red grey grey grey blue _h_807_10 FASLG_FAS__trimer__Src_Syk_1act_integral_to_membrane or TRAIL__trimer__extracellular_region grey grey _h_511_2 blue TAK1_TAB_family_1act_v2_TAK1_TAB2 grey red red blue _h_807_12 FASLG_FAS__trimer__Src_Syk_1act_integral_to_membrane or TRAIL__trimer__extracellular_region red grey grey grey blue _h_807_13 FASLG_FAS__trimer__Src_Syk_1act_integral_to_membrane or TRAIL__trimer__extracellular_region grey grey grey blue _h_2849 TAp73a__tetramer__nucleus_v3 grey blue _h_4519_1 (IL18_IL18R_1act or MKK4_1O_1O_1act) grey _h_2845 blue S1P1 _h_2844 blue GPC1_plasma_membrane and VEGFR1_homodimer_integral_to_membrane blue _h_2434_15 ((EGFR_EGFR_1act_integral_to_membrane_v1 or EGFR_EGFR_EGF_EGF_GRB2_GAB1_1act_integral_to_membrane_v1) and ( not (EGFR_EGFR_1ina_integral_to_membrane or EGFR_EGFR_EGF_EGF_GRB2_GAB1_1ina_integral_to_membrane))) _h_2846 blue NR0B2_nucleus grey grey grey blue _h_2842 ATM_3O_1N_site_of_double_strand_break blue _h_788 DAG_v2 and not Ca2__v1 grey blue _h_1234 IL23_IL23R_JAK2_TYK2_1act_integral_to_membrane _h_921_5 blue KSR_1act_plasma_membrane or RAS_family_GTP_1act_plasma_membrane_H_RAS_isoform_1_GTP_v1 or RAS_family_GTP_1act_plasma_membrane_N_RAS_GTP_v1 _h_6370 blue Calcineurin_A_alpha_beta_B1 red grey _h_1231 blue TRAIL__trimer__extracellular_region red grey blue _h_1230 Erk2_1O_1O_1act blue _h_4311_1 MEK1_1act or MEK1_2_active_1act grey grey grey blue _h_4692 (((((((((BRAF_1O_1act_plasma_membrane or BRAF_1act) or Ephrin_B_EPHB1_Src_p52_SHC_GRB2_1act_integral_to_membrane) or IQGAP1) or KSR_1act_plasma_membrane) or RAF1_1O_5O_1act_plasma_membrane) or RAF1_1act) or RAF1_4O_1act_plasma_membrane) or RAF1_BRAF_1act_v1) or SHH_Np_Cholesterol_extracellular_region) grey grey blue _h_4921 (JUN_FOS_1act_nucleus_v4 or cortisol_GR_alpha__dimer__1act_nucleus_v1) red _h_3211_1 blue FAK_Src_Yes_Fyn_1act_focal_adhesion_v2_Src_1act_1O_FAK_6O_1act blue _h_4690 ceramide grey grey red grey grey grey red grey _h_3464 blue ILK _h_4032 blue RACK1 blue _h_3466 (HIF1A_ARNT_Cbp_p300_Src_1_nucleus_Src_1_HIF1A_ARNT_CBP or HIF1A_ARNT_Cbp_p300_Src_1_nucleus_Src_1_HIF1A_ARNT_p300) grey _h_3460 blue E2_ER_alpha__dimer__1act_caveola and GTP_v1 blue _h_3461 STAT3__dimer__active_1act_nucleus _h_3462 blue IRS1 and RET51_GFRalpha1_GDNF_v1 blue _h_3463 NFAT1_1O_4O_2s_1act_nucleus _h_4927 blue PKN and TIF2 grey grey grey grey grey red red grey blue _h_600 (JUN_FOS_1act_nucleus_v1 and ( not cortisol_GR_alpha__monomer__nucleus)) _h_3824 blue TAp63g__tetramer__nucleus red grey _h_604 blue GMCSF_GMR_alpha_integral_to_membrane blue _h_4034 NFAT1_1O_4O_2s_1act_nucleus _h_606 blue NGF__dimer__extracellular_region and not NRAGE and (SH2B1__homopentamer__plasma_membrane or p75_NTR__1N_integral_to_membrane) _h_5117 blue Fibronectin_extracellular_matrix blue _h_153 (JUN_FOS_1act_nucleus_v1 and ( not cortisol_GR_alpha__monomer__JUN_FOS_1ina_nucleus)) _h_609 blue ATM blue _h_1036_29 Arf6_GTP_1act or Arf6_GTP_1act_plasma_membrane grey red red red grey _h_3820 blue Gq_family and S1P3 grey red blue _h_4704 MDM2 or YWHAS blue _h_2637_10 ((GNB1_GNG2_1act_cytoplasm or PDGF_BB_PDGFRB__dimer__1act_integral_to_membrane_v1) or SDF1_CXCR4_JAK2_1act_integral_to_membrane) red grey red red blue _h_2637_11 GNB1_GNG2_1act_cytoplasm or PDGF_BB_PDGFRB__dimer__1act_integral_to_membrane_v1 or SDF1_CXCR4_JAK2_1act_integral_to_membrane blue _h_5111 (E2F3_DP_RYBP_YY1_nucleus and ( not E2F7)) grey red blue _h_2637_12 GNB1_GNG2_1act_cytoplasm or PDGF_BB_PDGFRB__dimer__1act_integral_to_membrane_v1 or SDF1_CXCR4_JAK2_1act_integral_to_membrane red red blue _h_2637_15 ((GNB1_GNG2_1act_cytoplasm or PDGF_BB_PDGFRB__dimer__1act_integral_to_membrane_v1) or SDF1_CXCR4_JAK2_1act_integral_to_membrane) blue _h_2637_16 ((GNB1_GNG2_1act_cytoplasm or PDGF_BB_PDGFRB__dimer__1act_integral_to_membrane_v1) or SDF1_CXCR4_JAK2_1act_integral_to_membrane) blue _h_2637_17 ((GNB1_GNG2_1act_cytoplasm or PDGF_BB_PDGFRB__dimer__1act_integral_to_membrane_v1) or SDF1_CXCR4_JAK2_1act_integral_to_membrane) blue _h_2637_18 GNB1_GNG2_1act_cytoplasm or PDGF_BB_PDGFRB__dimer__1act_integral_to_membrane_v1 or SDF1_CXCR4_JAK2_1act_integral_to_membrane blue _h_2637_14 GNB1_GNG2_1act_cytoplasm or PDGF_BB_PDGFRB__dimer__1act_integral_to_membrane_v1 or SDF1_CXCR4_JAK2_1act_integral_to_membrane blue _h_3706 PKC_alpha_1act_plasma_membrane or PKC_beta_1act_plasma_membrane or RAP1_GTP_1act_endosome or RAS_family_GTP_1act_plasma_membrane_H_RAS_isoform_1_GTP_v1 or RAS_family_GTP_1act_plasma_membrane_N_RAS_GTP_v1 or RIN_GTP_1act or RIT1_GTP_1act grey _h_1060 blue Nephrin_NEPH1_podocin_membrane_raft_v1 grey _h_2485_1 blue PLC_beta3_cytoplasm grey grey red grey red _h_3073 blue ARF1_GDP_Membrin and ARF1_GTP_Membrin_1act_plasma_membrane and Brefeldin_A and p115 _h_3072 blue RHOA_GTP_1act blue _h_3071 PKC_delta _h_3070 blue p14ARF blue _h_3077 GRK2_1act _h_5118 blue TGFBR1__dimer__Par6_occludin_1ina_tight_junction _h_3075 blue PIAS1_nucleus _h_3074 blue TXA2_TP_beta_beta_Arrestin3_endosome grey grey blue _h_5119 RAS_family_GTP_1act_plasma_membrane_H_RAS_isoform_1_GTP_v1 or RAS_family_GTP_1act_plasma_membrane_N_RAS_GTP_v1 blue _h_5899_59 ErbB2_ErbB3_neuregulin_1_beta_1act_integral_to_membrane_v1 red _h_6127 blue LRP6_integral_to_membrane and WNT3A_2N_1S_1O_extracellular_region red red grey grey grey grey grey red grey grey grey _h_3852 blue CRK_II_cytoplasm and Tie2_Ang1_1act grey red red grey red grey red grey grey grey grey grey grey _h_635 blue netrin_1_DCC_FAK_Fyn_1act_integral_to_membrane_v2 grey grey grey _h_3263_57 blue FGFR1c_FGF4_1act red grey red _h_810 blue BRCA1_BARD1 red grey blue _h_4435 CBL_APS_CAP_Crk_II_C3G_membrane_raft grey grey _h_5309_4 blue Laminin_5 blue _h_353_1 PKC_zeta_1act or WNT5A_FZD2_ROR2_dimer__FLNA_1act_integral_to_membrane blue _h_6129 Pyk2_RAFTK_1O_1act_cytoplasm grey grey red grey red grey grey grey red blue _h_1094 ELK1_2O_1act_nucleus red grey blue _h_2489 Antigen_IgE_Fc_epsilon_R1_LYN_SYK_v2 or PKC grey blue _h_2488 T_DHT_AR_PRX1_nucleus blue _h_2210 DAG_v2 or PKC_theta_1O_1act_plasma_membrane or PKC_theta_1act_plasma_membrane blue _h_2211 Akt1_1O_1O_1act_plasma_membrane blue _h_2212 (HIF2A_ARNT_nucleus_v3 or sELK1) _h_2213 blue GTP_v1 and SDF1_CXCR4_1act_integral_to_membrane blue _h_2214 Cortactin_cell_cell_junction or Mena_1act_cell_cell_junction or WAVE2_1act_cell_cell_junction red _h_3331 blue LRP1 blue _h_2217 (Ca2__cytoplasm or STX1A_SNAP25_VAMP2_1act or STX1A_SNAP25_fragment_1_VAMP2_1act) and not (SNAP25_fragment_2_1ina or STX1A_1ina or VAMP2_fragments) _h_2218 blue PAK1_1O_1O_1act blue _h_2219 (Elf1_nucleus or JUNB_FOS_1act_nucleus) red red grey _h_4433 blue PLD2 grey grey grey red grey red red red grey _h_5159_1 blue VAV2 _h_5159_2 blue Vav3 blue _h_2486 Aiolos_1act_nucleus blue _h_3332 HIF1A_ARNT_nucleus red blue _h_3927 Ca2__cytoplasm red grey _h_3928 blue RHOGDI blue _h_4320 TAp63g__tetramer__1act_nucleus_v2 _h_4321 blue Protective_Antigen__PA__extracellular_region _h_4326 blue ppsTEM5 blue _h_4327 (AOF2 or AR_T_DHT_nucleus) blue _h_4324 STAT6__dimer__1act_nucleus_v1 blue _h_2480 Akt1_1O_1O_1act grey red red _h_2483 blue IL3_IL3RA_CSF2RB__dodecamer__JAK2_JAK2_1act_integral_to_membrane_v1 red grey grey _h_3079 blue BARD1 and EWS red blue _h_3078 not COUP_TFII_nucleus and (FOXA1_nucleus or SP1_3_nucleus) grey blue _h_5899_56 ErbB2_ErbB3_neuregulin_1_beta_1act_integral_to_membrane_v1 grey grey grey grey red grey grey red grey grey _h_5110 blue Axin1_APC_GSK3_beta_catenin_cytoplasm_v1 grey grey _h_5181 blue CDC42_GDP_1ina_cell_cell_junction and (FRG_1act_1O_cell_cell_junction or RAP1_GTP_1act_cell_cell_junction) _h_5180 blue IGF_1R_heterotetramer_IGF1_IRS1_caveola_v2 red red blue _h_5185 not MYC_Max_nucleus_v4 red red _h_5105_2 blue PPP2R1A_PPP2CA _h_5188 blue IL2_IL2R_alpha_beta_gamma_JAK1_LCK_JAK3_1act_integral_to_membrane red _h_5105_1 blue PPP2R1A_PPP2CA red red _h_168_4 blue FOXO3A_1O_1ina_2O_nucleus grey _h_168_2 blue YWHAS_nucleus _h_168_3 blue FOXO3A_1O_1ina_2O_nucleus _h_168_1 blue FOXO3A_1O_1ina_2O_nucleus blue _h_1747 p38alpha_beta_MNK1_1act_p38_alpha_1O_1O_1act_v2_MNK1_2O or p38alpha_beta_MNK1_1act_p38_beta_1O_1O_1act_MNK1_2O _h_1746 blue ER_beta_nucleus and INI1_BRG1_BAF57 blue _h_1745 ((JUN_FOSNFAT1_c_4_1act_nucleus_c_Jun_2O_NFAT1_1O_7O_2s_1act_nucleus_FOS_1O_1O or JUN_FOSNFAT1_c_4_1act_nucleus_c_Jun_2O_NFAT4_1act_nucleus_FOS_1O_1O) or JUN_FOSNFAT1_c_4_1act_nucleus_c_Jun_2O_NFATc_1act_nucleus_FOS_1O_1O) blue _h_1744 not IL6_IL6RA_gp130__dimer__JAK1_JAK1_LMO4_SOCS3_1act_integral_to_membrane and (IGF_1R_heterotetramer_IGF1_IRS1_caveola_v1 or IGF_1R_heterotetramer_IGF1_IRS1_caveola_v2 or IL6_IL6RA_gp130__dimer__JAK1_JAK1_LMO4_1act_integral_to_membrane_v1 or IL6_IL6RA_gp130__dimer__JAK1_JAK1_LMO4_1act_integral_to_membrane_v2) blue _h_1743 STAT3__dimer___1act_nucleus grey red red red grey red blue _h_5558 HIF1A_ARNT_nucleus red blue _h_3679 MAPKAPK2_1p_1act or MSK1_1act or MSK1_1p_1act or MSK2_1act or PKA_1act_nucleus or PLCgamma1_3O_1act_cytoplasm or RSK2_1act_3O_1O_nucleus or p38alpha_beta_MAPKAPK2_1act_MAPKAPK2_4O_1O_p38_alpha_1O_1O_1act_v2 or p38alpha_beta_MAPKAPK2_1act_MAPKAPK2_4O_1O_p38_beta_1O_1O_1act or p90S6K_2O_4O_1act_nucleus blue _h_3671 NFAT1_1O_7O_2s_1act_nucleus or NFAT4_1act_nucleus or NFATc_1act_nucleus blue _h_3670 beta_TrCP1 _h_3673 blue NOTCH1_heterodimer_integral_to_membrane and not Delta_3_integral_to_membrane blue _h_1019 (AR_T_DHT_nucleus or MED1) red blue _h_3674 CDC42_GTP_1act_plasma_membrane _h_969_2 blue MIZ_1 _h_2821_1 blue SMAD2_3_SMAD4_FOXO1_3a_4_1act_nucleus_v2_SMAD2_2O_1act_FOXO1_3a_4_1act_SMAD4 red _h_5459 blue TLE1_LEF1_1act_nucleus _h_5458 blue ((BCAP_1act_1O and CD19_1act_1O) and (B_cell_antigen_BCR_complex_LYN_SYK or VAV2_1act_1O)) grey grey grey grey _h_5456 blue Telomerase blue _h_5454 (aMb2_non_protein_ligands or alphaM_beta2_Integrin) _h_1299 blue Hsp90 and LKB1_nucleus grey _h_3173_4 blue TSC2_1O_1act _h_3173_5 blue TSC2_1O_1act _h_3173_2 blue TSC2_1O_1act _h_3173_3 blue TSC2_1O_1act grey red blue _h_1291 AMPKK1_active_1act_cytoplasm or AMPKK2_active_1act_cytoplasm grey blue _h_6241 ((CBP_nucleus or MYC_Max_TRRAP_GCN5_STAF65G_SPT3_TAF9_TAF10_TAF12_core_Mediator_nucleus) or p300_nucleus) _h_1292 blue EGFR_integral_to_membrane and ErbB2_integral_to_membrane blue _h_6247 AP1_1act_nucleus blue _h_6246 not MYC_Max_nucleus_v4 blue _h_1297 CDK2_1act_nucleus and not p27Kip1 blue _h_6244 PTP1B_plasma_membrane blue _h_3583 TAp63g__tetramer__1act_nucleus_v2 blue _h_3582 Erk2_1O_1O_1act grey blue _h_3580 Fyn_1O_1act grey red _h_3585 blue YWHAB_cytoplasm grey red _h_3589 blue alphav_beta8_Integrin_integral_to_membrane _h_3588 blue DAX_1_nucleus blue _h_830_1 PIN1_1act or PP2A_1act_v1 blue _h_830_2 PIN1_1act or PP2A_1act_v1 blue _h_830_3 PIN1_1act or PP2A_1act_v1 blue _h_5530 (STAT6__dimer__1act_nucleus_v1 and ( not STAT6__cleaved_dimer__nucleus_v1)) _h_5531 blue BRG1_nucleus and TCF3_beta_catenin_1act_nucleus blue _h_5532 Gamma_Secretase_plasma_membrane_v1 grey blue _h_770 PI_4_5_P2_synaptic_vesicle_membrane _h_5362 blue MYC_Max_nucleus_v4 blue _h_5537 Fra2_JUN_1act_nucleus_v2 red red _h_6408 blue Thrombin grey red blue _h_1918 WNT5A_FZD2_1act_integral_to_membrane grey grey grey grey grey red grey red red _h_3335_2 blue RAS_family_GTP_1act_plasma_membrane_N_RAS_GTP_v1 grey red grey grey grey red red grey red _h_3335_1 blue PI3K_cytoplasm grey grey red red _h_837 blue km23_1__dimer_ _h_2989 blue FOS_1act_nucleus grey blue _h_834 TAp63a__tetramer__1act_nucleus_v3 grey red blue _h_831 ROCK2_1act or ROCK_1act _h_2980 blue IL1RA blue _h_2981 NF_kappa_B_RelA_1act_nucleus_v1 and not I_kappa_B_beta_1act_nucleus blue _h_2982 RAC1_GTP_1act_v1 blue _h_2983 not CK2A1_nucleus and (Erk1_1O_1act_1O_nucleus or Erk1_1act_nucleus or Erk2_1O_1O_1act_nucleus or JNK2_1O_1O_1act or JNK2_1O_1act_1O_nucleus or Jnk1_1O_1act_1O or Jnk1_1O_1act_1O_nucleus or TCR_CD3_MHC_I_CD8_1act_integral_to_membrane or p38_alpha_1O_1O_1act_v2) blue _h_509 not Fra1_JUN_1act_nucleus blue _h_839 Alpha_Synuclein_PLC_beta_2 blue _h_2987 mTORC2 grey grey grey grey grey red blue _h_503 HECT9 grey red grey grey grey grey grey grey blue _h_4666 ((AIB1_nucleus or E2_ERA_nucleus) or FOXA1_nucleus) blue _h_4665 AR_T_DHT_nucleus or Oct_1 blue _h_4916 Erk2_1O_1O_1act or MAP3K11_1O_1O_1act grey blue _h_4910 RET51_GFRalpha1_GDNF_Dok4 grey grey grey blue _h_895 ATM_1O_1act grey blue _h_894 TRE17 red red blue _h_897 mTOR_1act _h_6334 blue TCF4_beta_catenin_1act_nucleus grey grey grey grey red red grey grey grey grey grey red red red red red grey _h_386 blue Calcineurin_A_alpha_beta_B1 red grey grey grey grey red grey grey _h_1688 blue Cone_Metarhodopsin_II_1act and (GRK1_1S or GRK7_1S_plasma_membrane) blue _h_6401 (( not EGF_extracellular_region) and ((ASM_1act or Acid_Sphingomyelinase_1act) or NSMASE_1act)) _h_6400 blue CXCL4_CXCR3_integral_to_membrane and GTP_v1 blue _h_6402 ((JUN_FOSNFAT1_c_4_1act_nucleus_c_Jun_2O_NFAT1_1O_7O_2s_1act_nucleus_FOS_1O_1O or JUN_FOSNFAT1_c_4_1act_nucleus_c_Jun_2O_NFAT4_1act_nucleus_FOS_1O_1O) or JUN_FOSNFAT1_c_4_1act_nucleus_c_Jun_2O_NFATc_1act_nucleus_FOS_1O_1O) blue _h_6405 ITCH_endosome and not VPS4 grey blue _h_6407 STAT3__dimer___1act_nucleus blue _h_2434_56 ((EGFR_EGFR_1act_integral_to_membrane_v1 or EGFR_EGFR_EGF_EGF_GRB2_GAB1_1act_integral_to_membrane_v1) and ( not (EGFR_EGFR_1ina_integral_to_membrane or EGFR_EGFR_EGF_EGF_GRB2_GAB1_1ina_integral_to_membrane))) blue _h_6409 MEK1_2O_1act_cytoplasm red red blue _h_1624 RAC1_GTP_1act_plasma_membrane grey red grey red grey red red grey grey grey grey grey grey red red blue _h_4026_8 EGFR_EGFR_EGF_EGF_1act_endosome_v2 grey grey red red grey grey grey grey red red blue _h_634 STAT1__dimer__1act_nucleus_v3 grey red grey grey red grey red grey _h_3561 blue E_cadherin_beta_catenin_alpha_catenin_integral_to_membrane and RAB5_GTP_1act_cell_cell_junction blue _h_4476 (AR_T_DHT_nucleus and ( not T_DHT_AR_Caspase_8_nucleus)) red _h_3560 blue Rac1_plasma_membrane grey red red grey grey grey grey blue _h_3562 Akt1_1O_1O_1act_plasma_membrane red grey grey red grey _h_396 blue RFFL_endosome red grey grey _h_6438_1 blue FAK_Src_Yes_Fyn_1act_focal_adhesion_v2_Fyn_1O_1act_FAK_6O_1act grey red red _h_684_2 blue Myb_nucleus _h_684_1 blue MYOD_Cbp_p300_MYOD_CBP _h_3566 blue RHOGDI red blue _h_4085_2 Lethal_Factor_cytoplasm blue _h_1539 GPC3_heterodimer_1act_plasma_membrane grey red red red red red blue _h_2760_2 CK1_alpha or CK1_epsilon _h_5410_6 blue YWHAG red grey red grey red red _h_3023_1 blue VAV2 _h_3023_2 blue Vav3 blue _h_5186 (AR_T_DHT_nucleus or Gelsolin) red _h_2300_1 blue MKP5_1act red grey grey red grey grey _h_630 blue FOS red red grey red _h_5477 blue RhoA_1act and Syndecan_2 grey _h_2157 blue LAT_GRAP2_SLP76_VAV1_1act_integral_to_membrane blue _h_2156 RPA_ATR_ATRIP_RAD17_RFC2_5_9_1_1_TopBP1_1act_nucleus blue _h_2155 ((FOXA2_nucleus_v1 or FOXA2_nucleus_v2) or Glucocorticoid_Receptor) red _h_2153 blue alphav_beta5_Integrin_integral_to_membrane _h_2152 blue Alpha_Synuclein_1act_1O_1O_cytoplasm and BAD_cytoplasm red _h_2150 blue DIABLO red blue _h_2409 ATF2_2O_1act_nucleus red blue _h_2159 AKT2_1O_1act _h_5109_2 blue HDAC2_nucleus and NF_kappa_B1_p50_RelA_Cbp_NF_kappa_B1_p50_p300_RelA red blue _h_1175 Gangliosides_and_protein_receptor__synaptotagmin_I_and_II__extracellular_region grey blue _h_1177 DAG_v2 blue _h_1170 Erk2_1O_1O_1act blue _h_1172 Ca2__cytoplasm or DAG_v2 _h_5025_1 blue FAK_Src_Yes_Fyn_1act_focal_adhesion_v2_Src_1act_1O_FAK_6O_1act grey grey blue _h_1179 RAC1_GTP_1act_v1 red red _h_1553 blue HES1_nucleus red grey red grey grey red grey red grey grey grey red grey grey red grey grey grey red red red red grey blue _h_275 E_cadherin_Ca2__beta_catenin_alpha_catenin_p120_catenin_cell_cell_junction_v1 red red blue _h_5370 CaM_1act_1O blue _h_1626 PI3K_1act_plasma_membrane_v2 or PI3K_beta_1act_plasma_membrane or PI3K_delta_1act_plasma_membrane or PI3K_gamma_p101_1act_plasma_membrane or PI3K_gamma_p84_1act_plasma_membrane or PI3K_p110_alpha_p55_gamma_1act_plasma_membrane or PI3K_p110_alpha_p85_beta_1act_plasma_membrane or PI3K_p110_beta_p55_gamma_1act_plasma_membrane or PI3K_p110_beta_p85_beta_1act_plasma_membrane or PI3K_p110_delta_p55_gamma_1act_plasma_membrane or PI3K_p110_delta_p85_beta_1act_plasma_membrane or PI_3_4_5_P3_plasma_membrane grey grey blue _h_2665 not K___cytoplasm and (Ca2__cytoplasm or MEK1_2O_1act_cytoplasm or MEK2_2O_1act_cytoplasm) red red grey grey red red grey grey red red red red grey _h_991 blue GSK3beta and dNp63a__tetramer__nucleus_v2 _h_992 blue Laminin_2_basement_membrane _h_993 blue RFXANK_nucleus blue _h_994 Sphingosine_1_phosphate grey blue _h_996 MRN_complex_ATM_MDC1_H2AX_RNF8_53BP1_BRCA1_1act_site_of_double_strand_break_v2 blue _h_449 Fra1_JUNB_1act_nucleus grey blue _h_999 p53__tetramer__nucleus_v2 grey grey red blue _h_443 TAB1 or TAB2 or TAK1_1p_1act blue _h_440 (AR_T_DHT_nucleus or FKBP52) grey red red red grey _h_1465 blue Laminin_11_basement_membrane blue _h_3448 (AR_T_DHT_nucleus or TZF_L_nucleus) blue _h_3449 STAT6__dimer__1act_nucleus_v1 grey grey _h_3445 blue 9cRA and TFIIH _h_3442 blue tensin red blue _h_3440 IL2_IL2R_alpha_beta_gamma_JAK1_LCK_JAK3_1act_integral_to_membrane blue _h_1463 STAT4__dimer__1act_nucleus_v2 grey red grey grey blue _h_2768 ATF2_2O_1act_nucleus grey _h_6301 blue Insulin_Receptor_Insulin_v2 and SHC_cytoplasm red grey red blue _h_198 p38alpha_beta_MAPKAPK2_1act_MAPKAPK2_4O_1O_p38_alpha_1O_1O_1act_v2 or p38alpha_beta_MAPKAPK2_1act_MAPKAPK2_4O_1O_p38_beta_1O_1O_1act _h_199 blue p27Kip1 blue _h_668 Disp1 red red grey grey grey red blue _h_192 N_cadherin_Ca2__p120_catenin_beta_catenin_gamma_catenin_alpha_catenin_cell_cell_junction _h_193 blue BRCA1 blue _h_666 E2_ERA__dimer__TIF2_P72_1act_nucleus blue _h_667 (E2F5_DP_Cbp_p300_CBP_DP_E2F5_1O or E2F5_DP_Cbp_p300_p300_DP_E2F5_1O) blue _h_196 STAT3_1O_v1 blue _h_197 Furin_or_Furin_like_Endopeptidase or MMP7 or Plasmin grey grey blue _h_1310 (AR_T_DHT_nucleus or JHDM2A) grey red blue _h_1633 beta_catenin_TCF1_CtBP_CBP_TLE1_AES_SMAD4_nucleus and not CtBP_CBP_TCF1_TLE1_AES_1act_nucleus blue _h_2938 p53__tetramer__nucleus_v2 red red _h_5590_1 blue PDGF_BB_PDGFRB__dimer__RasGAP_1act_integral_to_membrane grey _h_5590_2 blue PDGF_BB_PDGFRB__dimer__RasGAP_1act_integral_to_membrane grey grey grey _h_2934 blue S1P1_S1P_1act_v1 grey grey grey grey grey grey grey _h_5616 blue AKAP79 and PKA_1act grey grey _h_4432_1 blue Crk grey grey blue _h_2944_70 not E_cadherin_cytoplasm and (MAPK_14 or p120ctn) grey red grey red blue _h_3059 CDC42_GTP_1act _h_3058 blue IL1_beta_fragment_IL1R1_IL1RAP_PI3K_1act_integral_to_membrane and NF_kappa_B1_p50 blue _h_995 (JUN_JUN_FOS_RACO_1_1act_nucleus_JUN_RACO_1 or JUN_JUN_FOS_RACO_1_1act_nucleus_JUN_RACO_1_FOS) blue _h_6240 RAF1_1act_nucleus blue _h_3055 LEF1_beta_catenin_1act_nucleus_v1 red _h_3057 blue ER_beta_nucleus blue _h_3056 PTEN_v2 blue _h_3050 DAG_v2 _h_3053 blue alphaM_beta2_Integrin_integral_to_membrane blue _h_3052 Erk1_1O_1act_1O_nucleus or Erk2_1O_1O_1act_nucleus _h_2783_2 blue NONO _h_2879_2 blue Syndecan_1 blue _h_1166 RAP1_GTP_1act_cell_cell_junction _h_2879_1 blue Type_I_Collagen red grey grey grey _h_4825 blue CAMKIID or Ca2__v1 _h_2783_1 blue NONO red blue _h_4824 Pif1 grey grey red _h_3840_1 blue p16INK4a grey _h_4826 blue LIS1_1O_1act and NDEL1_Katanin_60_Dynein_heavy_chain blue _h_2439 Akt1_1O_1act_1O_1O_plasma_membrane grey red red blue _h_4820 HIF2A_ARNT_nucleus_v3 blue _h_3922 CDC42_GTP_1act_cell_cell_junction grey red _h_4530 blue Shf grey _h_3924 blue ACTN1 grey red grey grey red grey _h_998 blue eNOS_Caveolin_1_plasma_membrane grey grey grey blue _h_4490 SHH_Np_Cholesterol_extracellular_region blue _h_4491 (((((LPA_LPA1_2_3_LPA1_plasma_membrane_LPA or LPA_LPA1_2_3_LPA2_plasma_membrane_LPA) or LPA_LPA1_2_3_LPA3_plasma_membrane_LPA) or PI3K_1act_plasma_membrane_v2) or alpha4_beta7_Integrin_integral_to_membrane_v1) or alphav_beta3_Integrin_Del1) red grey grey red _h_2433 blue TCF4_beta_catenin_1act_nucleus and not TCF4_beta_catenin_KLF4_1ina_nucleus red blue _h_387 p38_alpha_1O_1O_1act_v2 or p38_beta_1O_1O_1act grey _h_1493 blue Syk grey red grey _h_2238 blue GRB2_SOS1_v2 red blue _h_5716 Fra2_JUNB_1act_nucleus_v1 _h_186_2 blue DVL3_cytoplasm grey blue _h_2232 BAD_1O_1act or BIM_1O_1O_1act or Caspase_8__tetramer__FADD_FADD_1act or LPA_LPA1 or LPA_LPA3 or Syndecan_2_PKC_delta blue _h_2233 FOXA2_nucleus_v1 blue _h_2231 DLG1_1O_cell_cell_junction or Src_1O_1act_cell_cell_junction _h_2236 blue alphav_beta3_Integrin_1act_integral_to_membrane blue _h_2237 DAG_v2 or TCR_CD3_MHC_II_CD4_LCK_1act_integral_to_membrane red grey blue _h_5051_78 (RAS_family_GTP_1act_plasma_membrane_H_RAS_isoform_1_GTP_v1 or RAS_family_GTP_1act_plasma_membrane_N_RAS_GTP_v1) _h_3304_2 blue GNB1_GNG2_1act_cytoplasm and SHP1 grey _h_1508 blue IL3RA_integral_to_membrane _h_3304_1 blue GNB1_GNG2_1act_cytoplasm and SDF1_CXCR4_1act_integral_to_membrane grey blue _h_3948 p70S6K_3O_4O red grey blue _h_3942 ABI1_Sra1_Nap1_cell_cell_junction or RHOA_GTP_1act_cell_cell_junction _h_3941 blue Syndecan_2_RACK1_membrane_raft red blue _h_3947 9cRA or FOXA1_nucleus grey _h_3945 blue TGFA_extracellular_region red blue _h_2096 RHOA_GTP_1act_plasma_membrane blue _h_5051_58 (RAS_family_GTP_1act_plasma_membrane_H_RAS_isoform_1_GTP_v1 or RAS_family_GTP_1act_plasma_membrane_N_RAS_GTP_v1) _h_2094 blue GMCSF_GMR_alpha_1act blue _h_2095 HRAS_GTP_1act_plasma_membrane or HRAS_GTP_1act_v1 blue _h_2092 dNp63a__tetramer__nucleus_v2 red blue _h_2090 PP5C_1act blue _h_2091 SKP2 grey red red grey blue _h_2099 p190RhoGAP_1act_1O grey grey _h_3356 blue alpha6_beta1_Integrin_integral_to_membrane _h_1431 blue PDGF_BB_PDGFRB__dimer__1act_integral_to_membrane_v1 grey grey _h_1490 blue NCoR2 and TAB2 grey grey blue _h_5899_33 ErbB2_ErbB3_neuregulin_1_beta_1act_integral_to_membrane_v1 grey _h_2552_2 blue (NICD_1O_nucleus and RBPJ_NCoR_HDAC1_nucleus_HDAC1_RBPSUH_SMRT__N_CoR2_) _h_2552_1 blue (MAML1_2 and RBPJ_NCoR_HDAC1_nucleus_HDAC1_RBPSUH_NCoR2) grey grey red grey blue _h_4026_4 EGFR_EGFR_EGF_EGF_1act_endosome_v2 grey grey grey grey grey _h_3354 blue NCK1 grey grey grey grey _h_1769 blue alpha1_beta1_Integrin_integral_to_membrane _h_1768 blue IL13RA1_JAK2 and not SOCS1 red blue _h_1761 dNp63a__tetramer__nucleus_v2 blue _h_1763 LIMK1_1O blue _h_1762 26S_Proteasome or UCHL1_v2 _h_1765 blue JUNB_nucleus _h_1764 blue STXBP1 blue _h_1767 UFD2a blue _h_3155 not Myb_nucleus _h_3613 blue (MEK2 and RAF1_1O_1act_v2) _h_3612 blue STAT3_1act_1O_cytoplasm blue _h_3610 DMN1_GTP_1act or EPS15_plasma_membrane _h_1495 blue ARF1_GTP_GGA3_1act_Golgi_to_ER_transport_vesicle_membrane blue _h_3616 PHD2 or PHD3 _h_3615 blue JAM_C_integral_to_membrane blue _h_3614 CEBPB or STAT6__dimer__1act_nucleus_v1 red blue _h_3619 beta_TrCP1_SCF_ubiquitin_ligase_complex blue _h_3618 ATM_3O_1N_site_of_double_strand_break grey blue _h_890 CD40LG or IL4_IL4R_JAK1_IL2R_gamma_JAK3_1act_integral_to_membrane blue _h_5475 proNGF__dimer__p75_NTR__Sortilin_1act_integral_to_membrane _h_5474 blue FGFR_FGF_Syndecan_2_FRS2_1act and FGFR_FGF_Syndecan_2_FRS2_Sprouty2_1ina and SOS1_cytoplasm and p52_SHC grey _h_597 blue Calcineurin_A_alpha_beta_B1_BCL2_1ina _h_5471 blue TAK1_TAB1_TAB2_integral_to_membrane grey blue _h_5473 TCPTP_p45_cytoplasm blue _h_5472 ((STAT5A_B__dimer__1act_nucleus or STAT5A__dimer__active_1act_nucleus_v2) or STAT5B__dimer__1act_nucleus) grey grey blue _h_5478 (NF_kappa_B1_p50_RelA and ( not cortisol_GR_alpha__monomer__nucleus)) blue _h_6265 not MYC_Max_nucleus_v4 blue _h_6264 PDK1_1act_plasma_membrane or PI3K_BCAP_CD19_1act_plasma_membrane blue _h_6267 Akt1_1O_1act_1O_1O_plasma_membrane red _h_1541 blue p75_NTR__1N_integral_to_membrane red _h_1543 blue MC4R and alpha_MSH grey red blue _h_2434_4 ((EGFR_EGFR_1act_integral_to_membrane_v1 or EGFR_EGFR_EGF_EGF_GRB2_GAB1_1act_integral_to_membrane_v1) and ( not (EGFR_EGFR_1ina_integral_to_membrane or EGFR_EGFR_EGF_EGF_GRB2_GAB1_1ina_integral_to_membrane))) blue _h_6269 c_Abl_1act_1O red grey grey _h_2559_1 blue MEP1B_1act_integral_to_membrane grey _h_2559_2 blue MEP1B_1act_integral_to_membrane red grey grey blue _h_2434_9 ((EGFR_EGFR_1act_integral_to_membrane_v1 or EGFR_EGFR_EGF_EGF_GRB2_GAB1_1act_integral_to_membrane_v1) and ( not (EGFR_EGFR_1ina_integral_to_membrane or EGFR_EGFR_EGF_EGF_GRB2_GAB1_1ina_integral_to_membrane))) red _h_755_1 blue GSK3A grey blue _h_5899_36 ErbB2_ErbB3_neuregulin_1_beta_1act_integral_to_membrane_v1 grey grey grey blue _h_807_9 FASLG_FAS__trimer__Src_Syk_1act_integral_to_membrane or TRAIL__trimer__extracellular_region grey grey blue _h_5512 TAp63g__tetramer__1act_nucleus_v2 blue _h_5513 (JUN_JUN_FOS_BAG1_1act_nucleus_BAG1_FOS_JUN_2O_2O or JUN_JUN_FOS_BAG1_1act_nucleus_JUN_BAG1_JUN_2O_2O) grey red red _h_5517 blue AgRP grey grey grey blue _h_5899_35 ErbB2_ErbB3_neuregulin_1_beta_1act_integral_to_membrane_v1 blue _h_1939 E2F1_DP_nucleus_v2 blue _h_6198 RAS_family_GTP_1act_plasma_membrane_H_RAS_isoform_1_GTP_v1 or RAS_family_GTP_1act_plasma_membrane_N_RAS_GTP_v1 red grey red grey grey red red blue _h_5899_34 ErbB2_ErbB3_neuregulin_1_beta_1act_integral_to_membrane_v1 grey grey red grey grey red grey grey grey red grey red grey grey _h_6245 blue CDK2_Cyclin_A_nucleus _h_1498 blue WWOX_cytoplasm red red blue _h_851 PDGFA _h_850 blue PDGFRA_integral_to_membrane grey grey _h_4700 blue IL1_beta_fragment_IL1R1_IL1RAP_MYD88_IRAK4_1act_integral_to_membrane and not IRAKM blue _h_4701 NEF _h_738 blue PTCH1_integral_to_membrane and SMO_integral_to_membrane grey grey red grey grey grey grey red grey red red grey grey grey _h_5953 blue SIRT1_nucleus red red _h_3164_1 blue RARs_THRs_THRs_Rar_gamma1 and SMRT__N_CoR2_ blue _h_757 MKK4_1O_1O_1act_cytoplasm red red blue _h_3559 ATF2_2O_1act_nucleus grey red _h_4649 blue PDGF_PDGFRA_1act red _h_1595 blue YWHAZ red blue _h_4641 RB1_nucleus _h_4640 blue Su_fu__cytoplasm _h_4643 blue Erk2_1O_1O_1act or IKK_alpha_homodimer_1act_cytoplasm or beta_TrCP1_SCF_ubiquitin_ligase_complex blue _h_4644 E2F4_DP2_TRRAP_nucleus _h_4646 blue uPA_uPAR_alphaM_beta2_Integrin_integral_to_membrane grey red grey grey red grey red red grey grey grey grey _h_274 blue SHP1 _h_277 blue netrin_1_DCC_FAK_Fyn_1act_integral_to_membrane_v2 _h_276 blue BAMBI and BMP2_4__homodimer__extracellular_region and BMPR2__homodimer__1act_integral_to_membrane and NOG and RGM_family blue _h_271 PKA_Family_active_1act blue _h_270 MYC_Max_Cbp_p300_1act_nucleus_MYC_1O_1u_v2_CBP_Max or MYC_Max_Cbp_p300_1act_nucleus_MYC_1O_1u_v2_p300_Max grey _h_272 blue MDM2 and RPL23 and RPL5 grey blue _h_279 ( not MYC_Max_MIZ_1_nucleus) _h_278 blue Insulin_Receptor_Insulin_Shc grey grey _h_919 blue (GTP_v1 and (((((Ca2__v1 or CaM) or DAG_v2) or RASGRF1_1act) or RASGRF2_1act) or RASGRP1_1act)) blue _h_752 not MYC_Max_nucleus_v4 grey _h_5804_1 blue FRS2_family_SHP2_1act and (BDNF__dimer__TRKB_1act_endosome_v2 or NGF__dimer__TRKA_1act_endosome or NT3__dimer__TRKC_1act_endosome or NT_4_5__dimer__TRKB_1act_endosome) red blue _h_6163_2 (CaM_Ca2__Calcineurin_A_alpha_beta_B1_1act_v2 or PKC_zeta) grey grey grey _h_5957 blue alpha4_beta1_Integrin_cell_leading_edge red grey blue _h_5183 TAp73b__tetramer__nucleus grey blue _h_2281_1 GM_CSF_extracellular_region or IL_3_extracellular_region grey grey grey blue _h_5899_80 ErbB2_ErbB3_neuregulin_1_beta_1act_integral_to_membrane_v1 blue _h_5899_81 ErbB2_ErbB3_neuregulin_1_beta_1act_integral_to_membrane_v1 red blue _h_5184 ILK_1act_1p grey grey _h_6469 blue PDGFRB_integral_to_membrane blue _h_6468 RAC1_GTP_1act_v1 and not RAC1_GDP_1ina_v1 grey blue _h_405 GPI_PLD1_1act blue _h_6463 COT_AKT1_1act_plasma_membrane or alphaV_beta3_Integrin_Osteopontin blue _h_6462 RAB11_GTP_1act _h_6461 blue alphav_Integrin grey blue _h_6467 ATM_3O_1N_site_of_double_strand_break grey blue _h_6465 Fra1_JUNB_1act_nucleus red grey grey blue _h_4694 ( not dNp63a__tetramer__nucleus_v2) grey grey grey grey grey grey grey blue _h_4914 TAB2 grey red blue _h_4517 (( not HBP1) and (E2F1_DP_nucleus_v2 or SP1)) _h_6044 blue Fibrinogen red _h_772 blue (E2_ER_alpha__dimer__PELP1_Src_p52_SHC_1act_plasma_membrane and IGF_1R_heterotetramer) grey grey red red red _h_168_6 blue YWHAZ_nucleus red grey grey _h_399_3 blue SMAD8A_2O_1act_cytoplasm grey red red _h_168_5 blue FOXO3A_1O_1ina_2O_nucleus blue _h_2890 Insulin_Receptor_Insulin_IRS1 red grey red red red grey blue _h_1831 NFAT1_1O_4O_2s_1act_nucleus grey blue _h_5289 dNp73b__tetramer__nucleus blue _h_5282 SCP1 or SCP2 grey grey _h_5281 blue FANCM_FAAP24_MHF1_MHF2_chromatin and FA_core_complex_chromatin blue _h_5286 MRP8_MRP14_TLR4_MD2__dimer__MYD88_TIRAP_1act_integral_to_membrane _h_5287 blue cIAP1_cIAP2_TRAF2 _h_5284 blue LRP5_integral_to_membrane and WNT7B_extracellular_region blue _h_5285 Akt1_1O_1O_1act_plasma_membrane grey blue _h_5051_21 (RAS_family_GTP_1act_plasma_membrane_H_RAS_isoform_1_GTP_v1 or RAS_family_GTP_1act_plasma_membrane_N_RAS_GTP_v1) grey red grey grey blue _h_5051_26 (RAS_family_GTP_1act_plasma_membrane_H_RAS_isoform_1_GTP_v1 or RAS_family_GTP_1act_plasma_membrane_N_RAS_GTP_v1) blue _h_5051_27 (RAS_family_GTP_1act_plasma_membrane_H_RAS_isoform_1_GTP_v1 or RAS_family_GTP_1act_plasma_membrane_N_RAS_GTP_v1) _h_6092 blue TAp73a__tetramer__nucleus_v3 blue _h_5051_29 (RAS_family_GTP_1act_plasma_membrane_H_RAS_isoform_1_GTP_v1 or RAS_family_GTP_1act_plasma_membrane_N_RAS_GTP_v1) grey _h_6091 blue MEKK1 red blue _h_6097 Blk_1O_1act_plasma_membrane or Fgr_1act_1O_plasma_membrane or Fyn_1act_1O_plasma_membrane or Hck_1act_1O_plasma_membrane or LYN_1O_1act_plasma_membrane or Lck_1O_1act_plasma_membrane or Src_1O_1act_plasma_membrane or Yes_1act_1O_plasma_membrane blue _h_6094 Syk_1O_1act or alphav_beta3_Integrin_c_FMS_Cbl_Cas blue _h_6095 MEKK1_2O_1act red _h_934 blue PROC blue _h_1837 Alpha_Synuclein_1act_1O_1O_cytoplasm grey red grey red _h_2395 blue VEGFR2__dimer__VEGFA__dimer__1act_integral_to_membrane_v1 _h_41 blue RAP1_GTP_1act_cell_leading_edge grey _h_2396 blue not ARF6_GDP_GULP_ACAP1 and (ACAP1_1act or ACAP2_1act or PI_4_5_P2 or Phosphatidic_acid) grey grey blue _h_2393 not PTP1B_AKT1 and (LRP or PTP1B_plasma_membrane) _h_4886_2 blue CXCL4 and CXCR3_B_integral_to_membrane _h_4886_3 blue CXCL4 and CXCR3_B_integral_to_membrane grey grey blue _h_2398 IL12_IL12R_TYK2_JAK2_1act_integral_to_membrane _h_4322 blue FE65_AICD blue _h_42 (IL12_IL12R_TYK2_JAK2_1act_integral_to_membrane or IL18_IL18R_1act) red blue _h_2437 p38_gamma_1O_1O_1act red red red red _h_44 blue Cyclin_D1_CDK4_1act blue _h_833 TCF4E_beta_catenin_1act_nucleus red _h_1164 blue HDAC3_cytoplasm and I_kappa_B_alpha_cytoplasm blue _h_807_4 FASLG_FAS__trimer__Src_Syk_1act_integral_to_membrane or TRAIL__trimer__extracellular_region red grey grey red grey red grey grey grey _h_1160 blue NF_Y blue _h_310_1 Arf6_GTP_1act grey blue _h_310_2 Arf6_GTP_1act grey grey blue _h_2172 BRG1_BAF47 _h_2174 blue EPHB1_integral_to_membrane red blue _h_2176 (p53__tetramer__nucleus_v2 and ( not POU4F1_nucleus)) grey grey grey red red _h_3088 blue RAB5_GTP_1act_v2 and RNTRE blue _h_1158 ATF2_2O_1act_nucleus _h_1159 blue Ran_GTP_Exportin_1_nucleus blue _h_1156 EPO_EPOR__dimer__LYN blue _h_5572 SGK1_1O_1O_1act_nucleus _h_1155 blue GLI3_cytoplasm blue _h_1152 HGF_dimer__MET_dimer__GAB1_N_WASP_NCK1_2_1act_integral_to_membrane_HGF_beta_NCK1_N_WASP_1act_MET_receptor_Alpha_v1_Gab1_1O_MET_receptor_Beta_5O_HGF_alpha or HGF_dimer__MET_dimer__GAB1_N_WASP_NCK1_2_1act_integral_to_membrane_HGF_beta_NCK2_N_WASP_1act_MET_receptor_Alpha_v1_Gab1_1O_MET_receptor_Beta_5O_HGF_alpha _h_1153 blue PTCH2_integral_to_membrane blue _h_1150 RXRs_RXRs_DNA_9cRA blue _h_1151 Chromosomal_passenger_complex_1act_kinetochore grey _h_3263_68 blue FGFR1c_FGF2_1act grey _h_3263_61 blue FGFR1b_FGF3_1act _h_3263_60 blue FGFR1c_FGF5_1act _h_3263_63 blue FGFR1b_FGF1_1act blue _h_1168 (( not (E2F4_DP2_p107_p130_nucleus_DP2_E2F4_p130 or E2F4_DP2_p107_p130_nucleus_DP2_p107_E2F4)) and (((B_Myb or E2F1_3_DP_nucleus_DP1_E2F1) or E2F1_3_DP_nucleus_DP1_E2F2) or E2F1_3_DP_nucleus_DP1_E2F3)) grey _h_3263_64 blue FGFR1c_FGF6_1act _h_3263_67 blue FGFR1b_FGF2_1act grey red grey red _h_4100 blue Fibronectin_extracellular_matrix _h_3083 blue Dynein_Light_chain and GIPC_plasma_membrane grey red grey grey red grey red blue _h_5067 Tie2_Ang2 blue _h_3222 not LEF1_beta_catenin_1act_nucleus_v1 blue _h_5051_33 (RAS_family_GTP_1act_plasma_membrane_H_RAS_isoform_1_GTP_v1 or RAS_family_GTP_1act_plasma_membrane_N_RAS_GTP_v1) red grey grey grey grey grey _h_4108 blue alphav_beta6_Integrin_integral_to_membrane red grey _h_5309_8 blue Laminin_1 blue _h_3672 IKK_beta_cytoplasm grey _h_5309_1 blue Laminin_11 _h_3675 blue BARD1 _h_5309_3 blue Laminin_2 _h_5309_2 blue Laminin_10 _h_5309_5 blue Laminin_v1 grey red blue _h_5638 JUN_2O_1act_nucleus red grey red _h_325_2 blue TGFB_TGFBR2_TGFBR1_STRAP_SMAD7_1act_integral_to_membrane and XIAP _h_1501_2 blue CD80_integral_to_membrane red grey grey blue _h_807_25 FASLG_FAS__trimer__Src_Syk_1act_integral_to_membrane or TRAIL__trimer__extracellular_region grey blue _h_468 CDK2_Cyclin_A blue _h_2923 BUB1_1O_kinetochore grey grey blue _h_460 mTORC2_1act _h_461 blue Jagged_2_integral_to_membrane red blue _h_463 p53__tetramer__nucleus_v2 blue _h_464 E2_ERA__dimer__AIB1_1act_nucleus blue _h_465 ATF2_2O_1act_nucleus or Cul3_1act blue _h_467 FOXM1B_nucleus _h_1501_1 blue CD86_integral_to_membrane blue _h_2285 MYC_Max_nucleus_v2 red red blue _h_807_24 FASLG_FAS__trimer__Src_Syk_1act_integral_to_membrane or TRAIL__trimer__extracellular_region grey grey red red red _h_3420 blue Gi_family and S1P3 grey _h_3423 blue MAL_dimer_ and SCAI_nucleus _h_3424 blue MIZ_1_cytoplasm blue _h_3425 PTP1B_plasma_membrane grey _h_3427 blue RET51_GFRalpha1_GDNF_SHC and SOS1_cytoplasm _h_1955 blue uPA_uPAR_1act_plasma_membrane_v2 grey blue _h_5452 TCR_CD3_MHC_II_CD4_1act_integral_to_membrane grey red _h_2841_3 blue FOS_3O_1O_1act_nucleus and JUN_2O_1act_nucleus and NFAT1_1O_7O_2s_1act_nucleus _h_2841_2 blue JUN_2O_1act_nucleus and NFATc_1act_nucleus and PPARG_1act_nucleus _h_2841_1 blue FOS_3O_1O_1act_nucleus and JUN_2O_1act_nucleus and PPARG_1act_nucleus _h_5450 blue RB1_nucleus red blue _h_4899 p53__tetramer__nucleus_v6 grey _h_5457 blue netrin_1_UNC5B_1act_integral_to_membrane blue _h_6494 TAp63a__tetramer__1act_nucleus_v1 blue _h_380_2 BRAF_14_3_3_1act_plasma_membrane_14_3_3_E_BRAF_1O_2O or BRAF_14_3_3_1act_plasma_membrane_BRAF_1O_2O_YWHAS or BRAF_14_3_3_1act_plasma_membrane_BRAF_1O_2O_YWHAZ or BRAF_14_3_3_1act_plasma_membrane_YWHAB_BRAF_1O_2O or BRAF_14_3_3_1act_plasma_membrane_YWHAG_BRAF_1O_2O or BRAF_14_3_3_1act_plasma_membrane_YWHAQ_BRAF_1O_2O or RAF1_14_3_3_1act_plasma_membrane_RAF1_1O_3O_14_3_3_E or RAF1_14_3_3_1act_plasma_membrane_RAF1_1O_3O_YWHAB or RAF1_14_3_3_1act_plasma_membrane_RAF1_1O_3O_YWHAG or RAF1_14_3_3_1act_plasma_membrane_RAF1_1O_3O_YWHAQ or RAF1_14_3_3_1act_plasma_membrane_RAF1_1O_3O_YWHAS or RAF1_14_3_3_1act_plasma_membrane_RAF1_1O_3O_YWHAZ or RAF1_BRAF_14_3_3_14_3_3_1act_plasma_membrane_v1 blue _h_3223_2 Lethal_Factor_cytoplasm and not Epigallocatechin_3_gallate__EGCG_ grey _h_6495 blue HIF1A_ARNT_nucleus and SMAD3_SMAD4_1act grey grey grey grey grey _h_3173_6 blue YWHAQ _h_6490 blue HGF_MET grey blue _h_1298 p53__tetramer__nucleus_v2 _h_5707 blue CHP1 and Ca2__CaM_1act grey blue _h_5705 p53__tetramer__nucleus_v2 red blue _h_1569 HIF1A_ARNT_nucleus grey red grey blue _h_1568 not XIAP and (Cytochrome_C_cytoplasm or XIAP_DIABLO_1ina) blue _h_4891 FOXM1C_2O_1act_nucleus _h_23 blue VCAM1_cytoplasm grey red blue _h_4893 TAp63b__tetramer__1act_nucleus_v1 red _h_6451 blue ROR2_integral_to_membrane and (FZD4_integral_to_membrane or LRP5_integral_to_membrane) grey red _h_3173_1 blue TSC2_1O_1act _h_795_1 blue RB1_E2F1_3_DP_HDAC1_nucleus_HDAC1_DP1_RB1_E2F2 grey _h_795_3 blue DNMT1 _h_6243 blue p75_NTR__1N_integral_to_membrane red red _h_6498 blue GTP_v1 and (PAR1_active_1act_integral_to_membrane or PAR4_active_1act_integral_to_membrane) _h_6242 blue TLE2_LEF1_1act_nucleus blue _h_2920 EGFR_EGFR_EGF_EGF_1act_endosome_v3 grey grey grey grey red blue _h_2944_69 not E_cadherin_cytoplasm and (MAPK_14 or p120ctn) grey _h_3880 blue Furin_or_Furin_like_Endopeptidase blue _h_6456 EGR2 blue _h_2944_62 not E_cadherin_cytoplasm and (MAPK_14 or p120ctn) blue _h_2944_63 not E_cadherin_cytoplasm and (MAPK_14 or p120ctn) blue _h_2944_60 not E_cadherin_cytoplasm and (MAPK_14 or p120ctn) grey _h_6341_2 blue FOXO1_nucleus blue _h_2944_67 not E_cadherin_cytoplasm and (MAPK_14 or p120ctn) blue _h_2944_64 not E_cadherin_cytoplasm and (MAPK_14 or p120ctn) grey red blue _h_645 dNp63a__tetramer__nucleus_v2 _h_640 blue Acid_Ceramidase or PDGFA _h_641 blue SMRT__N_CoR2_ red blue _h_2574 (T_DHT_AR_CDK6_nucleus and ( not T_DHT_AR_CyclinD1_nucleus)) _h_4257_2 blue Sck__SHC2__1act _h_3327 blue NFAT1_c_4_active_1act _h_4257_1 blue SHC3_1act grey red blue _h_2434_76 ((EGFR_EGFR_1act_integral_to_membrane_v1 or EGFR_EGFR_EGF_EGF_GRB2_GAB1_1act_integral_to_membrane_v1) and ( not (EGFR_EGFR_1ina_integral_to_membrane or EGFR_EGFR_EGF_EGF_GRB2_GAB1_1ina_integral_to_membrane))) blue _h_3326 p70S6K_1act_1p red red blue _h_2576 Erk2_1O_1O_1act _h_6457 blue MKK3 red red grey grey red red red red grey _h_3587 blue GMCSF_GMR_alpha_CSF2RB_JAK2__dodecamer__1act_integral_to_membrane_v3 grey blue _h_2572 NGF__dimer__p75_NTR__1act_integral_to_membrane red blue _h_3586 Fra1_JUN_1act_nucleus grey blue _h_380_3 BRAF_14_3_3_1act_plasma_membrane_14_3_3_E_BRAF_1O_2O or BRAF_14_3_3_1act_plasma_membrane_BRAF_1O_2O_YWHAS or BRAF_14_3_3_1act_plasma_membrane_BRAF_1O_2O_YWHAZ or BRAF_14_3_3_1act_plasma_membrane_YWHAB_BRAF_1O_2O or BRAF_14_3_3_1act_plasma_membrane_YWHAG_BRAF_1O_2O or BRAF_14_3_3_1act_plasma_membrane_YWHAQ_BRAF_1O_2O or RAF1_14_3_3_1act_plasma_membrane_RAF1_1O_3O_14_3_3_E or RAF1_14_3_3_1act_plasma_membrane_RAF1_1O_3O_YWHAB or RAF1_14_3_3_1act_plasma_membrane_RAF1_1O_3O_YWHAG or RAF1_14_3_3_1act_plasma_membrane_RAF1_1O_3O_YWHAQ or RAF1_14_3_3_1act_plasma_membrane_RAF1_1O_3O_YWHAS or RAF1_14_3_3_1act_plasma_membrane_RAF1_1O_3O_YWHAZ or RAF1_BRAF_14_3_3_14_3_3_1act_plasma_membrane_v1 red red _h_3011 blue VEGFR1_homodimer_plasma_membrane grey red blue _h_830_5 PIN1_1act or PP2A_1act_v1 grey grey grey grey red blue _h_6455 Erk2_1O_1O_1act grey red red red blue _h_2856 STAT5__dimer__1act_nucleus grey red red red red grey grey grey grey blue _h_2855 ErbB4_ErbB4_neuregulin_1_beta_neuregulin_1_beta_1act_integral_to_membrane_v2 grey _h_870 blue alpha4_beta1_Integrin_integral_to_membrane_v1 grey red grey grey red grey grey red red _h_5390 blue (EFA6_PI_4_5_P2_plasma_membrane and GTP_v1) grey blue _h_4417 FOXO1_SIRT1_1act_nucleus grey blue _h_5949 (FAK_Src_Yes_Fyn_1act_focal_adhesion_v2_Fyn_1O_1act_FAK_6O_1act or FAK_Src_Yes_Fyn_1act_focal_adhesion_v2_Src_1act_1O_FAK_6O_1act) grey grey blue _h_5538 Gamma_Secretase_plasma_membrane_v1 grey red blue _h_1101 Ca2__v1 or LIS1_IQGAP1 or VAV2_1act blue _h_5539 MEK1_3O_2O_1act_cytoplasm or MEK2_1act_cytoplasm red _h_5394 blue ELKS_cytoplasm grey red blue _h_3010 dNp63a__tetramer__nucleus_v2 grey grey red _h_4838_1 blue YWHAB_nucleus _h_4838_3 blue FOXO4_1O_2O_nucleus _h_4838_2 blue YWHAZ_nucleus _h_4838_5 blue FOXO4_1O_2O_nucleus grey red grey red grey grey blue _h_2738 FOXA2_nucleus_v1 or HNF1A__dimer__nucleus or SP1_3_nucleus grey _h_648 blue SCF_ubiquitin_ligases_v1 grey red grey red _h_854_2 blue GNAI2_GTP_1act_v2 grey _h_854_1 blue GNAI2_GTP_1act_v2 grey _h_3475_2 blue (( not p21CIP1_CDK2) and (((CDK2_Cyclin_E1_nucleus or RB1_E2F1_3_DP_nucleus_v2_DP1_E2F1_RB1_2N) or RB1_E2F1_3_DP_nucleus_v2_DP1_E2F3_RB1_2N) or RB1_E2F1_3_DP_nucleus_v2_DP1_RB1_2N_E2F2)) red grey red red blue _h_1706 HIF1A_nucleus or JUND_FOS_1act_nucleus _h_1705 blue CRK_II_cytoplasm red blue _h_1709 Akt1_1O_1act_1O_1O_plasma_membrane or SCF_KIT_1act or alpha6_beta1_Integrin blue _h_1708 STAT5A_B__dimer__1act_nucleus or STAT5A__dimer__active_1act_nucleus_v2 or STAT5B__dimer__1act_nucleus grey grey grey blue _h_3965 Myb_nucleus _h_3967 blue Caveolin_2 and HRAS_plasma_membrane _h_3966 blue VEGFD__dimer__extracellular_region and VEGFR3_integral_to_membrane red red blue _h_3963 Defensin_alpha_1 or Epigallocatechin_3_gallate__EGCG_ grey grey grey _h_3016 blue LRP6_integral_to_membrane and WNT2_extracellular_region red blue _h_2615 (GNB1_GNG2_1act or Gq_family_GTP_1act) grey _h_2617 blue beta_catenin_nucleus blue _h_3639 p53__tetramer__nucleus_v2 red blue _h_2612 STAT6__dimer__1act_nucleus_v1 grey red blue _h_3634 IKK_beta or IKKs _h_3637 blue ILK_PINCH1_alpha_parvin grey grey blue _h_2619 PTP1B_1act or TCPTP_p45_1act red _h_3632 blue RAB11_GDP_integral_to_membrane red _h_4675 blue CD14_integral_to_membrane and TLR4_integral_to_membrane red _h_5499 blue TNFR1A and TNF_alpha_extracellular_region _h_2166_6 blue PDGF_BB_PDGFRB__dimer__RasGAP_1act_integral_to_membrane _h_5497 blue GNAQ_1act_plasma_membrane blue _h_2637_13 GNB1_GNG2_1act_cytoplasm or PDGF_BB_PDGFRB__dimer__1act_integral_to_membrane_v1 or SDF1_CXCR4_JAK2_1act_integral_to_membrane blue _h_5495 ( not (NF_kappa_B1_p50_RelA_Cbp_cortisol_GR_alpha__monomer__HDAC2_HDAC2_NF_kappa_B1_p50_Glucocorticoid_Receptor_CBP_RelA_cortisol or NF_kappa_B1_p50_RelA_Cbp_cortisol_GR_alpha__monomer__HDAC2_HDAC2_NF_kappa_B1_p50_Glucocorticoid_Receptor_p300_RelA_cortisol)) blue _h_5494 p53__tetramer__nucleus_v2 red red blue _h_5491 p53__tetramer__nucleus_v2 blue _h_5490 (JUN_JUN_FOS_RACO_1_1act_nucleus_JUN_RACO_1 or JUN_JUN_FOS_RACO_1_1act_nucleus_JUN_RACO_1_FOS) red red _h_6289 blue SRA1 grey blue _h_6287 TCPTP_p45_nucleus blue _h_6286 ( not TAp73a__tetramer__nucleus_v3) _h_6285 blue PDGF_BB_1act_extracellular_region blue _h_6284 E2_ERA__dimer__1act_nucleus _h_6283 blue PI3K_cytoplasm _h_6282 blue BMP6__homodimer_ and BMPR1A_1B__homodimer__integral_to_membrane and BMPR2__homodimer__1act_integral_to_membrane and FETUA _h_6281 blue Aprataxin grey grey red red grey grey grey blue _h_4677 ITK_1act_2O_plasma_membrane or TCR_CD3_MHC_II_CD4_LCK_ZAP_70_1act_integral_to_membrane or TCR_CD3_MHC_I_CD8_LCK_ZAP_70_1act_integral_to_membrane red blue _h_5717 mTOR_1act red red red red grey grey grey grey grey grey _h_2763 blue KIR4_2_1act_integral_to_membrane and not Spermidine red grey grey grey grey grey grey grey red grey red grey grey _h_2948 blue alpha9_beta1_Integrin_integral_to_membrane _h_2949 blue Fra2_1O_1O_nucleus grey red grey _h_2946 blue MRN_complex_ATM_MDC1_H2AX_RNF8_1act_site_of_double_strand_break _h_2947 blue GPC1_plasma_membrane blue _h_2940 PHD2 or PHD3 blue _h_2941 Src_1act_1O _h_2942 blue GNAT2_GTP_1act blue _h_2943 Fibronectin_alpha4_beta1_Integrin_cell_leading_edge or cAMP grey _h_879 blue ATF2_2O_1act _h_878 blue beta_Arrestin2_cytoplasm grey _h_4728 blue FKBP12_ALK2__dimer__1ina_integral_to_membrane and MIS__dimer__extracellular_region blue _h_4729 FOXA1_nucleus and not FOXA2_nucleus_v1 _h_4726 blue Dynein_heavy_chain and MAP1B_1act blue _h_872 GSK3beta_2O_2O_1act_cytoplasm blue _h_4724 FOXO3A_nucleus grey _h_4722 blue alphaM_beta2_Integrin blue _h_4723 CBP_nucleus or p300_nucleus grey red grey red grey grey grey grey red red grey grey red red grey grey blue _h_2944_76 not E_cadherin_cytoplasm and (MAPK_14 or p120ctn) grey red blue _h_2637_19 GNB1_GNG2_1act_cytoplasm or PDGF_BB_PDGFRB__dimer__1act_integral_to_membrane_v1 or SDF1_CXCR4_JAK2_1act_integral_to_membrane red blue _h_4622 p62DOK_3O_1act_plasma_membrane red red grey red blue _h_4625 STAT1__dimer__1act_nucleus_v4 _h_4624 blue G12_G13_cytoplasm and S1P2 grey blue _h_4629 Cyclin_B1_CDK1_1act_v1 blue _h_4628 LKB1_MO25_STRADA_STRADB_cytoplasm_v2 _h_2787 blue APC_1act_cytoplasm and Axin1_1act_cytoplasm and (NOTCH1_precursor or PP2A_1act_cytoplasm) grey red grey blue _h_380_6 BRAF_14_3_3_1act_plasma_membrane_14_3_3_E_BRAF_1O_2O or BRAF_14_3_3_1act_plasma_membrane_BRAF_1O_2O_YWHAS or BRAF_14_3_3_1act_plasma_membrane_BRAF_1O_2O_YWHAZ or BRAF_14_3_3_1act_plasma_membrane_YWHAB_BRAF_1O_2O or BRAF_14_3_3_1act_plasma_membrane_YWHAG_BRAF_1O_2O or BRAF_14_3_3_1act_plasma_membrane_YWHAQ_BRAF_1O_2O or RAF1_14_3_3_1act_plasma_membrane_RAF1_1O_3O_14_3_3_E or RAF1_14_3_3_1act_plasma_membrane_RAF1_1O_3O_YWHAB or RAF1_14_3_3_1act_plasma_membrane_RAF1_1O_3O_YWHAG or RAF1_14_3_3_1act_plasma_membrane_RAF1_1O_3O_YWHAQ or RAF1_14_3_3_1act_plasma_membrane_RAF1_1O_3O_YWHAS or RAF1_14_3_3_1act_plasma_membrane_RAF1_1O_3O_YWHAZ or RAF1_BRAF_14_3_3_14_3_3_1act_plasma_membrane_v1 blue _h_369 dNp63b__tetramer__nucleus red grey red grey blue _h_5259 B_cell_antigen_BCR_complex_LYN_v2 red grey grey red red red red blue _h_259 JUNB__dimer__1act_nucleus_v1 blue _h_258 PTPRM_1act_cell_cell_junction blue _h_257 SCF_KIT_1act blue _h_256 EOMES blue _h_255 IL6_IL6RA_gp130__dimer__JAK1_JAK1_LMO4_1act_integral_to_membrane_v2 red red _h_5593 blue Btk_1act and FADD grey blue _h_1041 TCPTP_p45_nucleus grey red grey _h_1259_2 blue FGFR4_FGF19 _h_1259_1 blue FGFR_FGF_v2 red red red red red grey blue _h_2988 CK1_alpha or CK1_epsilon or PRKACA _h_4838_6 blue YWHAQ_nucleus grey grey grey grey grey red blue _h_835 Gangliosides_and_protein_receptor__synaptotagmin_I_and_II__extracellular_region blue _h_6445 RIP2_NOD2 red blue _h_5838 ( not WAVE2_Nap1_Sra1_ABI1) _h_6441 blue beta_catenin_1act_nucleus and not Nemo_like_kinase_1act blue _h_6440 Caspase_3__tetramer__1act blue _h_6443 (MYOD_Cbp_p300_MYOD_CBP or MYOD_Cbp_p300_MYOD_p300) and not (ATBF1_A or MYOD_Cbp_p300_Myb_MYOD_CBP_Myb or MYOD_Cbp_p300_Myb_MYOD_p300_Myb) grey grey grey _h_6449 blue MFGE8 blue _h_6448 JUN_FOS_ER_alpha_1act_nucleus blue _h_832 p38alpha_beta_MNK1_1act_p38_alpha_1O_1O_1act_v2_MNK1_2O or p38alpha_beta_MNK1_1act_p38_beta_1O_1O_1act_MNK1_2O grey blue _h_3391 ((((CDC42_GTP_1act or Ephrin_B1_EPHB1_2_1act_integral_to_membrane_v1) or Ephrin_B2_EPHB4_1act_integral_to_membrane) or Gab1_1O_cytoplasm) or IL2_IL2R_alpha_beta_gamma_JAK1_LCK_JAK3_SYK_1act_integral_to_membrane) _h_3396 blue TACE grey grey red _h_3398 blue (N_cadherin_Ca2__p120_catenin_beta_catenin_gamma_catenin_alpha_catenin_cell_cell_junction and RAC1_GDP_1ina_v1) blue _h_3399 dNp63a__tetramer__nucleus_v2 red _h_5934 blue pro_uPA_1ina_extracellular_region red _h_5936 blue CaM_Ca2__Calcineurin_A_alpha_beta_B1_1act_v2 and Jnk1_1O_1act_1O blue _h_5930 IHH_N_PTCH1_integral_to_membrane grey red _h_5933 blue TRKA_NEDD4_2_integral_to_membrane red grey _h_5676_2 blue HDAC1_nucleus and RB1_E2F1_3_DP_nucleus_v3_DP1_RB1_E2F2 _h_5676_3 blue CHE_1 and HDAC1_nucleus _h_5676_1 blue CHE_1 and RB1_E2F1_3_DP_nucleus_v3_DP1_E2F1_RB1 _h_4130 blue ((((BAMBI and BMP2_4__homodimer__extracellular_region) and BMPR1A_1B__homodimer__integral_to_membrane) and BMPR2__homodimer__1act_integral_to_membrane) and RGM_family) grey red red grey red grey blue _h_3012 RXRs_LXRs_DNA_Oxysterols_1act_v2 blue _h_838 Myb_nucleus or SP1_3_nucleus red red blue _h_4533 TCPTP_p45_nucleus blue _h_3827 p38alpha_beta_MAPKAPK2_1act_MAPKAPK2_4O_1O_p38_alpha_1O_1O_1act_v2 or p38alpha_beta_MAPKAPK2_1act_MAPKAPK2_4O_1O_p38_beta_1O_1O_1act grey grey grey red grey grey grey grey grey grey red grey _h_5591 blue RELN_LRP8 and RELN_VLDLR grey grey red grey grey grey grey grey grey _h_4497 blue PECAM1 and SPHK1 _h_2379 blue ASK1 blue _h_2378 not E2F6_DP_nucleus _h_2377 blue YY1_nucleus blue _h_2376 IGF_1R_heterotetramer_IGF1_IRS1_GRB2_Sos_Shc_RACK1_caveola _h_2375 blue SMAD4_nucleus _h_2374 blue N_WASP blue _h_2373 (((JUN_FOSNFAT1_c_4_1act_nucleus_c_Jun_2O_NFAT1_1O_7O_2s_1act_nucleus_FOS_1O_1O or JUN_FOSNFAT1_c_4_1act_nucleus_c_Jun_2O_NFAT4_1act_nucleus_FOS_1O_1O) or JUN_FOSNFAT1_c_4_1act_nucleus_c_Jun_2O_NFATc_1act_nucleus_FOS_1O_1O) and ( not ((JUN_NFAT1_c_4_p21SNFT_1act_nucleus_c_Jun_2O_NFAT1_1O_7O_2s_1act_nucleus_p21SNFT or JUN_NFAT1_c_4_p21SNFT_1act_nucleus_c_Jun_2O_NFAT4_1act_nucleus_p21SNFT) or JUN_NFAT1_c_4_p21SNFT_1act_nucleus_c_Jun_2O_NFATc_1act_nucleus_p21SNFT))) _h_2372 blue (ELMO1_DOCK2_1act_cell_leading_edge and RAC2_GDP_1ina) blue _h_2371 STAT1__dimer__1act_nucleus_v1 or cortisol_GR_alpha__monomer__nucleus blue _h_2370 CK1_gamma_1act_membrane_raft _h_2264_2 blue C3G_1O and GAB2 grey red _h_5245 blue netrin_1_extracellular_region grey red grey red red grey _h_3602 blue alphaIIb_beta3_Integrin_integral_to_membrane grey blue _h_367 p53__tetramer__nucleus_v2 red grey grey grey grey red _h_2755 blue TACI red grey blue _h_619 SHP1_1act blue _h_2026 alphav_beta3_Integrin_VEGFR2_VEGFA__dimer__1act_plasma_membrane grey grey grey grey grey grey _h_366 blue WNT5A_FZD2_ROR2_dimer__1act_integral_to_membrane _h_2119 blue Laminin_2_basement_membrane _h_2118 blue IL6_IL6RA_gp130__dimer__JAK1_JAK1_LMO4_1act_integral_to_membrane_v2 and STAT3__dimer___1act_nucleus blue _h_616 (AR_T_DHT_nucleus or NRIP1) blue _h_2113 FOXO3A_SIRT1_1act_nucleus red blue _h_2111 Aurora_A_1O_1act or Aurora_A_BORA blue _h_2110 ( not Fra1_USF2_1act_nucleus) blue _h_2117 (((((((BRAF_1O_1act_cytoplasm or COT) or MEKK1_2O_1act) or PI3K_gamma_p101_1act_cytoplasm) or PI3K_gamma_p84_1act_cytoplasm) or PKC_delta_1act_plasma_membrane) or RAF1_1O_1O_1act_cytoplasm) or SHC_GRB2_SOS1_GAB1_1act_integral_to_membrane) red red _h_3003_2 blue p38alpha_beta_MAPKAPK2_1act_MAPKAPK2_4O_1O_p38_beta_1O_1O_1act grey grey blue _h_2021 PI_3_4_5_P3_cell_cell_junction _h_3003_4 blue TCF3_v1 grey blue _h_1130 dNp63a__tetramer__nucleus_v2 _h_613 blue alphav_beta3_Integrin_integral_to_membrane blue _h_1132 STAT6__dimer__1act_nucleus_v1 blue _h_2752 ((((((PKC_beta_1act_plasma_membrane or PKC_delta_1act_plasma_membrane) or PKC_epsilon_1act_plasma_membrane) or PKC_isoenzymes_1act_plasma_membrane) or PKC_theta_1act_plasma_membrane) or PRKCG_1act_plasma_membrane) or PRKCH_1act_plasma_membrane) _h_1134 blue ACK1 _h_1135 blue Fc_gamma_RIIa grey blue _h_1137 FGFR_FGF_Syndecan_2_1act _h_3263_43 blue FGFR1b_FGF2_1act blue _h_6056 AS160_2O_1ina_3O grey blue _h_2323 (((Interferon_receptor_Type_I_IFN or JUN_FOSNFAT1_c_4_1act_nucleus_c_Jun_2O_NFAT1_1O_7O_2s_1act_nucleus_FOS_1O_1O) or JUN_FOSNFAT1_c_4_1act_nucleus_c_Jun_2O_NFAT4_1act_nucleus_FOS_1O_1O) or JUN_FOSNFAT1_c_4_1act_nucleus_c_Jun_2O_NFATc_1act_nucleus_FOS_1O_1O) grey blue _h_611 (IHH_N_PTCH1_integral_to_membrane and ( not GLI3R_1ina)) _h_3263_45 blue FGFR1b_FGF10_1act grey grey red _h_3263_49 blue FGFR1c_FGF2_1act _h_610 blue BoNT_B_Light_Chain_1act_cytoplasm blue _h_6054 MMP3 or MMP7 or Plasmin grey grey red _h_2327 blue EGFR and PI3K_beta_plasma_membrane and (LPA_LPA1_2_3_LPA1_plasma_membrane_LPA or LPA_LPA1_2_3_LPA2_plasma_membrane_LPA or LPA_LPA1_2_3_LPA3_plasma_membrane_LPA) _h_3063 blue VEGFA121__dimer__extracellular_region blue _h_6053 MYC_Max_nucleus_v2 grey grey grey _h_2028 blue FKBP12_ALK1__dimer__1ina_integral_to_membrane grey blue _h_1224 LEF1_beta_catenin_1act_nucleus_v1 _h_1225 blue Myoferlin and VEGFR2__dimer__VEGFA__dimer__1act_integral_to_membrane_v1 grey grey blue _h_3714 ILK _h_5533_1 blue EGR4_nucleus _h_5533_2 blue NFAT1_1O_7O_2s_1act_nucleus _h_5533_3 blue NFATc_1act_nucleus grey red red blue _h_1220 CaMKIIA_1O_1act grey red grey grey grey grey red grey blue _h_380_5 BRAF_14_3_3_1act_plasma_membrane_14_3_3_E_BRAF_1O_2O or BRAF_14_3_3_1act_plasma_membrane_BRAF_1O_2O_YWHAS or BRAF_14_3_3_1act_plasma_membrane_BRAF_1O_2O_YWHAZ or BRAF_14_3_3_1act_plasma_membrane_YWHAB_BRAF_1O_2O or BRAF_14_3_3_1act_plasma_membrane_YWHAG_BRAF_1O_2O or BRAF_14_3_3_1act_plasma_membrane_YWHAQ_BRAF_1O_2O or RAF1_14_3_3_1act_plasma_membrane_RAF1_1O_3O_14_3_3_E or RAF1_14_3_3_1act_plasma_membrane_RAF1_1O_3O_YWHAB or RAF1_14_3_3_1act_plasma_membrane_RAF1_1O_3O_YWHAG or RAF1_14_3_3_1act_plasma_membrane_RAF1_1O_3O_YWHAQ or RAF1_14_3_3_1act_plasma_membrane_RAF1_1O_3O_YWHAS or RAF1_14_3_3_1act_plasma_membrane_RAF1_1O_3O_YWHAZ or RAF1_BRAF_14_3_3_14_3_3_1act_plasma_membrane_v1 grey grey red grey grey grey blue _h_5051_20 (RAS_family_GTP_1act_plasma_membrane_H_RAS_isoform_1_GTP_v1 or RAS_family_GTP_1act_plasma_membrane_N_RAS_GTP_v1) red blue _h_4574_1 EHD4_1act red grey grey blue _h_4574_2 EHD4_1act grey grey red blue _h_2434_19 ((EGFR_EGFR_1act_integral_to_membrane_v1 or EGFR_EGFR_EGF_EGF_GRB2_GAB1_1act_integral_to_membrane_v1) and ( not (EGFR_EGFR_1ina_integral_to_membrane or EGFR_EGFR_EGF_EGF_GRB2_GAB1_1ina_integral_to_membrane))) _h_5802_2 blue CaMK_II_delta_B and IFN_gamma_IFN_gammaR_JAK1_JAK1_JAK2_JAK2_1act _h_3402 blue Aurora_C and INCENP blue _h_3403 ((E2F1_DP_nucleus_v2 or SP1) and ( not (E2F7_nucleus or E2F8_nucleus))) blue _h_3401 (T_DHT_AR_TIF2_nucleus_v1 and ( not Filamin_A_C_terminal_fragment)) _h_3406 blue alphaM_beta2_Integrin grey _h_3404 blue positive_transcription_elongation_factor_complex_b_nucleus blue _h_3405 ( not dNp63g__tetramer__nucleus) blue _h_4919 Fra1_JUNB_1act_nucleus blue _h_3408 SCF_KIT_1act or SCF_KIT_EPO_EPOR_1act _h_3409 blue Vitronectin_extracellular_matrix red red red grey _h_469_1 blue p300 _h_497_1 blue (HDJ2 and testosterone_cytoplasm) grey _h_3375 blue alpha_parvin red grey red blue _h_1884_1 (((BRAF_1act or RAF1_1O_1O_1act_cytoplasm) or RAF1_1O_1act_v1) or RAF1_1act) red grey red _h_4917 blue TCF1E_TLE2_1act_nucleus red blue _h_5163 ( not (MYC_Max_HDAC3_nucleus or MYC_Max_MIZ_1_nucleus)) blue _h_4664 Src_1act_1O red blue _h_3376 PIP5K1C_1act_1p _h_4662 blue IRAK4 grey red grey _h_4297_2 blue PDGF_BB_PDGFRB__dimer__GAB1_N_WASP_1act_integral_to_membrane grey grey blue _h_1032_2 PI_3_4_5_P3_plasma_membrane blue _h_5728 DEC1_BMAL1 or NR1D1 or PER1_2___CRY1_2_nucleus or PER1_TIMELESS grey grey blue _h_5721 Furin_or_Furin_like_Endopeptidase blue _h_5720 DMN1_GTP or HGS_endosome or beta_Arrestin2_plasma_membrane or beta_Arrestin3_plasma_membrane blue _h_5722 p53__tetramer__nucleus_v2 blue _h_5725 Plasmin_1act grey blue _h_5727 c_Abl_1act_1O _h_5726 blue FOXM1B_nucleus blue _h_402 ADAM10 _h_403 blue DCC_integral_to_membrane and netrin_1_extracellular_region grey red _h_6174_2 blue GSC_nucleus and RB1_E2F1_3_DP_nucleus_v3_DP1_E2F3_RB1 _h_6174_3 blue (RB1_E2F1_3_DP_nucleus_v3_DP1_E2F1_RB1 and SPI1_nucleus) blue _h_404 (ATFA and ( not RB1_nucleus)) _h_6174_1 blue (RB1_E2F1_3_DP_nucleus_v3_DP1_RB1_E2F2 and SPI1_nucleus) grey grey grey grey _h_781_1 blue ((MAML2_nucleus and SHARP_RBPJ_nucleus) and p300_nucleus) _h_932 blue IL5_IL5RA_CSF2RB__hexamer__JAK2_JAK2_1act_v1 blue _h_5168 ATF2_2O_1act_nucleus grey grey blue _h_307 (AR_T_DHT_nucleus and ( not HOXB13)) grey grey grey red grey grey blue _h_2944_48 not E_cadherin_cytoplasm and (MAPK_14 or p120ctn) grey grey blue _h_2944_44 not E_cadherin_cytoplasm and (MAPK_14 or p120ctn) blue _h_2944_45 not E_cadherin_cytoplasm and (MAPK_14 or p120ctn) blue _h_2944_46 not E_cadherin_cytoplasm and (MAPK_14 or p120ctn) blue _h_2944_47 not E_cadherin_cytoplasm and (MAPK_14 or p120ctn) blue _h_2944_40 not E_cadherin_cytoplasm and (MAPK_14 or p120ctn) blue _h_2944_41 not E_cadherin_cytoplasm and (MAPK_14 or p120ctn) blue _h_2944_42 not E_cadherin_cytoplasm and (MAPK_14 or p120ctn) blue _h_2944_43 not E_cadherin_cytoplasm and (MAPK_14 or p120ctn) grey blue _h_508 Erk1_1O_1act_1O_nucleus or Erk2_1O_1O_1act_nucleus red grey grey blue _h_2434_13 ((EGFR_EGFR_1act_integral_to_membrane_v1 or EGFR_EGFR_EGF_EGF_GRB2_GAB1_1act_integral_to_membrane_v1) and ( not (EGFR_EGFR_1ina_integral_to_membrane or EGFR_EGFR_EGF_EGF_GRB2_GAB1_1ina_integral_to_membrane))) grey grey red grey _h_2166_5 blue Lck _h_3862_1 blue Ephrin_A5_EPHA3_4_5_6_7_1act red grey blue _h_6159 CHK2_1O_nucleus grey grey grey red red grey grey red blue _h_2434_80 ((EGFR_EGFR_1act_integral_to_membrane_v1 or EGFR_EGFR_EGF_EGF_GRB2_GAB1_1act_integral_to_membrane_v1) and ( not (EGFR_EGFR_1ina_integral_to_membrane or EGFR_EGFR_EGF_EGF_GRB2_GAB1_1ina_integral_to_membrane))) red grey grey red grey _h_1650_3 blue p38_beta_1O_1O_1act _h_401_3 blue RB1_E2F1_3_DP_nucleus_v3_DP1_E2F3_RB1 grey _h_2575_1 blue Fyn and VEGFR2__dimer__VEGFA__dimer__1act_integral_to_membrane_v1 grey grey red red grey _h_3214_1 blue (NCK1_cytoplasm and PDGF_BB_PDGFRB__dimer__1act_integral_to_membrane_v1) _h_3214_2 blue (NCK2_cytoplasm and PDGF_BB_PDGFRB__dimer__1act_integral_to_membrane_v1) _h_5565_2 blue FOS red grey grey red red red grey grey red blue _h_5971 Cathepsin_D_ceramide or TNF_alpha_TNFR1A_TRADD_MADD_cIAP2_RIP_TRAF2_RAIDD blue _h_2434_17 ((EGFR_EGFR_1act_integral_to_membrane_v1 or EGFR_EGFR_EGF_EGF_GRB2_GAB1_1act_integral_to_membrane_v1) and ( not (EGFR_EGFR_1ina_integral_to_membrane or EGFR_EGFR_EGF_EGF_GRB2_GAB1_1ina_integral_to_membrane))) _h_5802_4 blue Ca2__CaM_1act and IFN_gamma_IFN_gammaR_JAK1_JAK1_JAK2_JAK2_1act red blue _h_807_47 FASLG_FAS__trimer__Src_Syk_1act_integral_to_membrane or TRAIL__trimer__extracellular_region red _h_2062_1 blue PAK1 grey _h_1828_3 blue NOTCH2_heterodimer_integral_to_membrane _h_1828_2 blue JAG1_integral_to_membrane _h_1046 blue FZD1_integral_to_membrane and LRP6_integral_to_membrane _h_5972 blue INCENP_v1 and hSgo1 red red blue _h_2434_16 ((EGFR_EGFR_1act_integral_to_membrane_v1 or EGFR_EGFR_EGF_EGF_GRB2_GAB1_1act_integral_to_membrane_v1) and ( not (EGFR_EGFR_1ina_integral_to_membrane or EGFR_EGFR_EGF_EGF_GRB2_GAB1_1ina_integral_to_membrane))) red _h_5470 blue Syndecan_2 grey grey grey grey red grey red grey _h_3187 blue GPC3_plasma_membrane and SHH_Np_Cholesterol_extracellular_region red blue _h_3185 dNp63b__tetramer__nucleus red _h_3183 blue HGF_dimer__MET_dimer__GAB1_1act_integral_to_membrane_v4 _h_3182 blue cortisol_GR_alpha__dimer__nucleus_v4 _h_3181 blue ICAT_nucleus grey _h_4691 blue VEGFR2_integral_to_membrane red grey blue _h_3188 Jnk1_1O_1act_1O _h_2584 blue MRN_complex_ATM_MDC1_H2AX_RNF8_53BP1_BRCA1_ABRA1_1act_site_of_double_strand_break blue _h_2585 Blk_1O_1act_plasma_membrane or Fgr_1act_1O_plasma_membrane or Fyn_1act_1O_plasma_membrane or Hck_1act_1O_plasma_membrane or LYN_1O_1act_plasma_membrane or Lck_1O_1act_plasma_membrane or Src_1O_1act_plasma_membrane or Yes_1act_1O_plasma_membrane grey blue _h_2580 IL12_IL12R_TYK2_JAK2_1act_integral_to_membrane _h_2581 blue NCK1_Dok_R and (RAC1_GTP_1act_v1 or ROS) _h_2582 blue BRCA1 and Neurofibromin and Oct_1 _h_2583 blue netrin_1_DCC_1act_integral_to_membrane grey grey _h_2588 blue Ca2__v1 and IQGAP1_CaM _h_2589 blue FADD red red grey grey _h_5129 blue (IKK_beta_cytoplasm and NEMO_1u_cytoplasm) red red blue _h_5125 (FOXA1_nucleus and ( not p53__tetramer__nucleus_v2)) _h_5124 blue FOS_1act_nucleus _h_5120 blue MDM2 grey red grey grey blue _h_1729 S1P_S1P3_Gi _h_1728 blue p300_nucleus blue _h_6119 ceramide and not OKADAIC_ACID grey grey red blue _h_6115 not RSPO1 blue _h_6114 p53__tetramer__nucleus_v2 blue _h_1721 IL12_IL12R_TYK2_JAK2_1act_integral_to_membrane _h_1720 blue Mad_Max_nucleus red blue _h_6110 PI_5_P or netrin_1_DCC_1act_integral_to_membrane grey _h_3988 blue GRB2_SOS1_v2 and (BDNF__dimer__TRKB_1act_endosome_v2 or NGF__dimer__TRKA_1act_endosome or NT3__dimer__TRKC_1act_endosome or NT_4_5__dimer__TRKB_1act_endosome) grey _h_3986 blue CBL_5O_1act_cytoplasm and TCR_CD3_MHC_II_CD4_LCK_ZAP_70_1act_integral_to_membrane _h_3983 blue uPAR_plasma_membrane blue _h_1915_1 SHC_RasGAP_1act blue _h_1915_2 SHC_RasGAP_1act _h_3980 blue alphav_beta3_Integrin_integral_to_membrane grey grey grey red blue _h_2639 (NFATc_1act_nucleus and ( not JNK2_1O_1O_1act)) blue _h_2636 (ETS1_nucleus or JUN_FOS_1act_nucleus_v4) red blue _h_2634 Jak2_1act_8O_cytoplasm _h_2632 blue RasGAP_p62DOK_1act red red _h_2631 blue TNF_alpha_integral_to_membrane grey red blue _h_5654 TAp63b__tetramer__1act_nucleus_v1 grey grey red _h_506 blue NuRD_MBD2_Complex__MeCP1__nucleus grey grey blue _h_1589 MST4_1act_plasma_membrane _h_1588 blue TNF_alpha_TNFR2__cleaved__TRAF1_TRAF2_1act_integral_to_membrane and cIAP2 and sTNF_alpha_TNFR1A_TRADD_RIP_TRAF2_1act_integral_to_membrane blue _h_5656 (GATA3 or NFAT1_1O_4O_2s_1act_nucleus) red red grey _h_1580 blue Delta_1_membrane_raft and not Delta_3_integral_to_membrane _h_1583 blue CSF2RB__dimer__integral_to_membrane _h_1582 blue JUN_nucleus _h_2851 blue ErbB4_CYT2_integral_to_membrane _h_1584 blue AR_T_DHT_nucleus _h_1587 blue FAK_1O_1act_focal_adhesion _h_1586 blue SHIP blue _h_3970_9 ETA_receptor_Endothelin_1_Gs_GTP_1act_integral_to_membrane or PKC_epsilon_1act_cytoplasm blue _h_3970_8 ETA_receptor_Endothelin_1_Gs_GTP_1act_integral_to_membrane or PKC_epsilon_1act_cytoplasm grey grey red blue _h_3970_1 ETA_receptor_Endothelin_1_Gs_GTP_1act_integral_to_membrane or PKC_epsilon_1act_cytoplasm red grey blue _h_3970_2 ETA_receptor_Endothelin_1_Gs_GTP_1act_integral_to_membrane or PKC_epsilon_1act_cytoplasm grey blue _h_3970_4 ETA_receptor_Endothelin_1_Gs_GTP_1act_integral_to_membrane or PKC_epsilon_1act_cytoplasm blue _h_3970_7 ETA_receptor_Endothelin_1_Gs_GTP_1act_integral_to_membrane or PKC_epsilon_1act_cytoplasm blue _h_3970_6 ETA_receptor_Endothelin_1_Gs_GTP_1act_integral_to_membrane or PKC_epsilon_1act_cytoplasm red grey red grey grey grey grey red grey grey grey grey grey _h_2053 blue GTP_v1 and (Ca2__v1 or CalDAG_GEF1_1act or CalDAG_GEFIII_1act or DAG_v2 or RASGRF1_1act or RASGRP1_1act or Sema3e_Plexin_D1_Rnd2) _h_3263_8 blue FGFR1b_FGF10_1act red blue _h_4299 (ELK1_1O_4O_1act_nucleus or SRF_nucleus) _h_4296 blue GTP_v1 and Gai_GDP_1ina _h_4808_1 blue Src_family_SYK_family_BLNK_LAT_BTK_ITK_1act_SYK_Family_Kinases_active_1act_BTK_ITK_active_1act_LAT_10O_1act_LYN_1act_1O grey red _h_4808_4 blue Src_family_SYK_family_BLNK_LAT_BTK_ITK_1act_SYK_Family_Kinases_active_1act_BTK_ITK_active_1act_LAT_10O_1act_Lck_1O_1act blue _h_4293 Akt1_1O_1O_1act_plasma_membrane grey red _h_3263_7 blue FGFR1c_FGF2_1act red _h_3263_4 blue FGFR1c_FGF1_1act grey blue _h_2966 (FKBP12 and ( not FK506)) grey blue _h_2964 HIF2A_ARNT_nucleus_v3 blue _h_2965 (E2F1_DP_nucleus_v4 and ( not (E2F4_DP2_p107_p130_nucleus_DP2_E2F4_p130 or E2F4_DP2_p107_p130_nucleus_DP2_p107_E2F4))) blue _h_2962 (Ephrin_B1_EPHB3 or RHOA_GTP_1act_plasma_membrane) red blue _h_2960 FOXA1_nucleus _h_2961 blue SMAD3_SMAD4_1act_nucleus grey grey grey red _h_2968 blue 14_3_3_E_cytoplasm red red red blue _h_5051_24 (RAS_family_GTP_1act_plasma_membrane_H_RAS_isoform_1_GTP_v1 or RAS_family_GTP_1act_plasma_membrane_N_RAS_GTP_v1) grey grey red grey blue _h_4749 CaM_Ca2__Calcineurin_A_alpha_beta_B1_1act_v2 _h_3003_3 blue p38alpha_beta_MAPKAPK2_1act_MAPKAPK2_4O_1O_p38_beta_1O_1O_1act grey blue _h_4740 Erk2_1O_1O_1act blue _h_4741 ( not (MYC_Max_nucleus_v4 or p107_nucleus)) _h_4742 blue PI_4_5_P2 blue _h_4743 PKC_1act blue _h_4744 IL2_extracellular_region blue _h_4745 SRF_dimer__MAL_dimer__1act_nucleus _h_4746 blue TLR6_integral_to_membrane red red grey grey red red red _h_424 blue JUND_nucleus red red red red blue _h_4609 N_cadherin_Ca2__p120_catenin_beta_catenin_gamma_catenin_alpha_catenin_cell_cell_junction grey blue _h_4605 (((CBP_1act or HIF1A_ARNT_1act_nucleus) or HNF4) or p300_1act) red _h_4607 blue PKC_zeta_Par3_Par6 red blue _h_4601 FASLG_FAS__trimer__FADD_FADD_CASP8_CASP8_1act_integral_to_membrane_v2 or FASLG_FAS__trimer__FADD_FADD_RIP_1act_integral_to_membrane or TRAIL_TRAILR1_FADD_TRADD_RIP_integral_to_membrane or TRAIL_TRAILR2_FADD_TRADD_RIP_integral_to_membrane or sTNF_alpha_TNFR1A_TRADD_RIP_TRAF2_TAK1_TAB_family_MEKK3_1act_integral_to_membrane_TNFR1A_MEKK3_1p_TRADD_TRAF2_1u_RIP_1u_TAB1_TAK1_1act_sTNF_alpha or sTNF_alpha_TNFR1A_TRADD_RIP_TRAF2_TAK1_TAB_family_MEKK3_1act_integral_to_membrane_TNFR1A_MEKK3_1p_TRADD_TRAF2_1u_RIP_1u_TAB2_TAK1_1act_sTNF_alpha blue _h_4600 PPM1A blue _h_4603 beta_TrCP1_SCF_ubiquitin_ligase_complex blue _h_1075 ATF2_2O_1act_nucleus grey grey grey grey grey red red red red red grey red grey red _h_1615_3 blue GPC1_plasma_membrane and TGFB1__dimer__1act_extracellular_region and TGFBR1__dimer__integral_to_membrane _h_1615_2 blue GPC1_plasma_membrane and TGFBR1__dimer__integral_to_membrane and TGFBR2__dimer__1act_integral_to_membrane _h_1615_1 blue GPC1_plasma_membrane and TGFB2__dimer__1act_extracellular_region and TGFBR2__dimer__1act_integral_to_membrane blue _h_239 Erk2_1O_1O_1act _h_1557 blue (RAB5_GDP_1ina_early_endosome and Src_1act_1O) red red blue _h_3043 BDNF__dimer__TRKB_1act_endosome_v2 or NGF__dimer__TRKA_1act_endosome or NT3__dimer__TRKC_1act_endosome or NT_4_5__dimer__TRKB_1act_endosome grey _h_5157 blue IL1RAP and IL1_beta_fragment_1act blue _h_230 MRN_complex_ATM_1act_site_of_double_strand_break blue _h_233 HIF2A_ARNT_nucleus_v3 grey blue _h_235 Ephrin_A5_EPHA5_caveola blue _h_234 E2_ERA__dimer__1act_nucleus grey blue _h_3217 Fra1_JUND_1act_nucleus _h_3216 blue GTP_v1 and TXA2_extracellular_region and not TXA2_TP_beta_1ina_integral_to_membrane blue _h_3215 STAT3__dimer___1act_nucleus grey red red red red _h_3219 blue sTNF_alpha_TNFR1A_1act_integral_to_membrane _h_3218 blue alpha4_beta1_Integrin_cell_leading_edge grey grey red grey grey grey red red _h_1679 blue alpha7X1_beta1_Integrin grey red red grey red red red _h_401_2 blue HDAC3_nucleus grey _h_1561 blue NRG1_extracellular_region red blue _h_3378 ATF2_2O_1act_nucleus grey blue _h_3374 IL2_IL2R_beta_gamma_JAK1_LCK_JAK3_PI3K_1act_integral_to_membrane red red _h_3377 blue C3G_cytoplasm blue _h_3371 RHOA_GTP_1act_plasma_membrane _h_3372 blue TCF4_beta_catenin_1act_nucleus blue _h_2058 PLK1_1O_1act and not PP2A_alpha_B56_centrosome grey grey red grey red grey grey _h_5916 blue TCF4_TLE1_HDAC1_1act_nucleus red _h_5914 blue NFATc_A_alpha_cytoplasm blue _h_5915 (E2F1_DP_nucleus_v4 and ( not (E2F4_DP2_p107_p130_nucleus_DP2_E2F4_p130 or E2F4_DP2_p107_p130_nucleus_DP2_p107_E2F4))) _h_5912 blue ARF1_GTP_1act_Golgi_to_ER_transport_vesicle_membrane grey blue _h_5910 MYC_Max_nucleus_v2 _h_5911 blue STAT5A blue _h_1097 (MYC_Max_nucleus_v2 or SMAD3_SMAD4_1act_nucleus) blue _h_2794_1 (((PAK2_1act or PAK4_1act) or RAS_family_GTP_1act_H_RAS_isoform_1_GTP_v1) or RAS_family_GTP_1act_N_RAS_GTP_v1) red grey red red grey _h_423 blue FOS_3O_2O_nucleus grey red red red _h_1093 blue GSK3beta_1act_cytoplasm and not (DVL1_1act_cytoplasm or FRAT1 or PP2A_1act_cytoplasm) red grey grey grey _h_540_2 blue CDK2_Cyclin_A_nucleus _h_540_3 blue CDK2_Cyclin_A_nucleus blue _h_4487 ( not Interferon_type_I) grey red _h_4486 blue alpha6_beta1_Integrin_integral_to_membrane grey grey grey red blue _h_347 not STAT1__dimer__1act_v1 grey grey _h_1799 blue IL6_IL6RA_gp130__dimer__JAK1_JAK1_LMO4_1act_integral_to_membrane_v2 and PIAS1 grey blue _h_4481 PI3K_beta_1act_plasma_membrane or PKC_epsilon_1act red blue _h_4480 RPA_ATR_ATRIP_RAD17_RFC2_5_9_1_1_TopBP1_1act_nucleus red grey red grey _h_1099 blue EGFR_integral_to_membrane and ErbB4_CYT2_integral_to_membrane grey grey _h_1098 blue Hhip_integral_to_membrane red grey grey red grey grey grey red _h_2358 blue IL23R_JAK2_integral_to_membrane and IL23_extracellular_region grey grey _h_6473 blue EGFR_EGFR_EGF_EGF_integral_to_membrane_v2 blue _h_3577 STAT4__dimer__1act_nucleus_v2 _h_2351 blue alpha1_Integrin blue _h_2350 RXRs_LXRs_DNA_Oxysterols_1act_v2 _h_2353 blue LAT_GRAP2_SLP76_1act_integral_to_membrane grey grey blue _h_2354 MIB1_cytoplasm _h_2357 blue FGFR1_integral_to_membrane and GPC1_plasma_membrane blue _h_2356 Calpain_1 red _h_5599 blue GRB2_cytoplasm and SHC_cytoplasm grey red grey grey red grey grey grey red grey _h_3571 blue FANCD2 grey grey blue _h_2134 E2_ERA__dimer__1act_nucleus blue _h_2137 HRAS_GTP_1act_v2 or PAK1_1act blue _h_2136 FASLG_FAS__trimer__FADD_FADD_1act_integral_to_membrane or TRAIL_TRAILR1_FADD_integral_to_membrane or TRAIL_TRAILR2_FADD_integral_to_membrane _h_2131 blue CBL_APS_CAP _h_2130 blue SMAD3_SMAD4_1act_nucleus _h_2133 blue p14ARF grey _h_2138 blue IRS1_1act_1O and PTP1B_plasma_membrane grey blue _h_446 Myb_nucleus grey grey grey red blue _h_754_1 DNM1_GTP_1act or RAB5_GTP_1act_cytoplasm blue _h_754_2 DNM1_GTP_1act or RAB5_GTP_1act_cytoplasm _h_4199 blue CaM_Ca2_ grey red blue _h_4195 SET7 grey grey blue _h_4196 RPA_ATR_ATRIP_RAD17_RFC2_5_9_1_1_TopBP1_1act_nucleus grey grey _h_4193 blue alpha2_beta1_Integrin_integral_to_membrane grey _h_3263_25 blue FGFR1b_FGF2_1act red _h_3263_27 blue FGFR1c_FGF4_1act _h_3263_26 blue FGFR1c_FGF4_1act _h_5346 blue MET_integral_to_membrane grey _h_3263_23 blue FGFR1c_FGF6_1act _h_3263_22 blue FGFR1c_FGF4_1act red grey _h_3263_29 blue FGFR1c_FGF1_1act _h_3263_28 blue FGFR1b_FGF2_1act red grey grey grey red _h_3250_1 blue YWHAS _h_3250_2 blue YWHAQ _h_3250_3 blue SIK1_1O_1act_cytoplasm _h_3250_4 blue SIK1_1O_1act_cytoplasm grey grey grey grey red red grey grey blue _h_3390 N_cadherin_Ca2__p120_catenin_beta_catenin_gamma_catenin_alpha_catenin_cell_cell_junction grey grey grey grey grey blue _h_3130_6 CRIPTO_GPC1_1act_plasma_membrane _h_6012 blue mTORC1_1act red red blue _h_5364_1 PDGF_BB_PDGFRB__dimer__1act_integral_to_membrane_v1 grey _h_2248_1 blue Fra1_JUNB_1act_nucleus _h_2248_2 blue NFAT1_1O_7O_2s_1act_nucleus _h_2248_3 blue Fra1_JUNB_1act_nucleus red grey red red grey grey blue _h_5051_30 (RAS_family_GTP_1act_plasma_membrane_H_RAS_isoform_1_GTP_v1 or RAS_family_GTP_1act_plasma_membrane_N_RAS_GTP_v1) _h_5356 blue NSMASE and sTNF_alpha_TNFR1A_1act_integral_to_membrane blue _h_5357 E2_ERA__dimer__TIF2_CoCoA_1act_nucleus blue _h_5350 LEF1_beta_catenin_1act_nucleus_v1 blue _h_5351 Caspase_1__tetramer__1act red _h_5353 blue ROCK and RhoA_1act and VEGFR2_VEGFA__dimer__1act_plasma_membrane and Vitronectin and alphav_beta3_Integrin grey grey grey grey _h_5358 blue PP5C grey red blue _h_1444 not dNp63a__tetramer__nucleus_v2 blue _h_1445 Akt1_1O_1O_1act or PDK1_1O_1act_plasma_membrane _h_1446 blue B7_family_CD28_1act_integral_to_membrane_v2 and PKC_theta_1O_plasma_membrane blue _h_1447 Antigen_IgE_Fc_epsilon_R1_LYN_SYK_v2 blue _h_6320 (( not GAB2_1act_plasma_membrane) and (BCL10_MALT1_TRAF6_1act or PDK1_CARD11_BCL10_MALT1_TRAF6_1act)) blue _h_6321 TCR_CD3_MHC_II_CD4_LCK_ZAP_70_1act_integral_to_membrane blue _h_6322 (E2_ERA__dimer__1act_nucleus and ( not E2_ERA__dimer__DP97_1act_nucleus)) _h_1443 blue Ryk_integral_to_membrane and WNT1_extracellular_region blue _h_2676 CK2A1 grey blue _h_1119 Myb_nucleus red grey blue _h_2677 Caspase_3_1act red grey grey grey blue _h_3369_1 TC10_GTP_CIP4_1act_membrane_raft blue _h_4259 TGFB_TGFBR2_TGFBR1_1act_integral_to_membrane _h_2675 blue GMCSF_GMR_alpha_CSF2RB_JAK2__dimer__1act_integral_to_membrane red _h_1413 blue pro_uPA_1ina_extracellular_region red _h_1647 blue TAp63g__tetramer__nucleus grey blue _h_1128 LIMK1_1O_1act or LIMK2_1act red blue _h_3369_2 TC10_GTP_CIP4_1act_membrane_raft grey blue _h_1411 PAK1_1O_1O_1act grey red grey red blue _h_6377 Erk2_1O_1O_1act grey _h_1416 blue SP1 blue _h_2225 Akt1_1O_1act_plasma_membrane_v2 grey _h_1415 blue NCK1_cytoplasm and p62DOK_2O blue _h_2224 (beta_catenin_TCF1_CtBP_CBP_TLE1_AES_SMAD4_nucleus and ( not CtBP_CBP_TCF1_TLE1_AES_1act_nucleus)) blue _h_1414 PI_3_4_5_P3_plasma_membrane grey grey grey blue _h_5173_1 cortisol _h_4231_2 blue MAPKAPK2 red red red _h_2328_2 blue BAG1_nucleus _h_2328_1 blue JUN_JUN_FOS_1act_nucleus_v1_FOS_JUN_2O_2O red grey blue _h_938_4 PIN1_1act or PP2A_1act_v1 _h_5741 blue (ARF1_GDP_1ina_plasma_membrane and Arf6_GTP_1act_plasma_membrane) blue _h_938_6 PIN1_1act or PP2A_1act_v1 blue _h_938_1 PIN1_1act or PP2A_1act_v1 blue _h_5746 (cortisol_GR_alpha__dimer__nucleus_v4 and ( not cortisol_GR_alpha__dimer__1ina_cytoplasm_v2)) blue _h_938_3 PIN1_1act or PP2A_1act_v1 blue _h_938_2 PIN1_1act or PP2A_1act_v1 red _h_5749 blue ErbB4_ErbB4_neuregulin_1_beta_neuregulin_1_beta_1act_integral_to_membrane_v2 _h_5748 blue FOS_3O_1O_1act_nucleus and JUN_2O_1act_nucleus and NFAT1_1O_4O_2s_1act_nucleus grey grey red grey grey grey blue _h_428 PLK1_1O_1act red _h_939 blue beta_parvin _h_936 blue (((ARHGAP10_1act_Golgi_apparatus or ARHGAP17_1act) or RALBP1_1act) or RHOGAP_1act_cytoplasm) blue _h_937 USP7 grey blue _h_427 not MYC_Max_nucleus_v4 red grey _h_930 blue Kininogen grey red grey red red grey blue _h_2926 CSK_1act grey red grey grey grey grey grey grey red grey _h_6193 blue Jak2_1act_2O red blue _h_5830 TCF4_beta_catenin_1act_nucleus blue _h_2944_26 not E_cadherin_cytoplasm and (MAPK_14 or p120ctn) red red grey grey blue _h_2944_23 not E_cadherin_cytoplasm and (MAPK_14 or p120ctn) blue _h_2944_20 not E_cadherin_cytoplasm and (MAPK_14 or p120ctn) blue _h_2944_21 not E_cadherin_cytoplasm and (MAPK_14 or p120ctn) blue _h_2944_28 not E_cadherin_cytoplasm and (MAPK_14 or p120ctn) grey grey _h_689 blue GR_beta_nucleus and TIF2_nucleus red grey red grey grey blue _h_680 T_DHT_AR_nucleus grey blue _h_682 SMAD3_SMAD4_TFE3_1act_nucleus blue _h_683 PDK1_Src_Hsp90_1act or PDK1_Src_Hsp90_1act_plasma_membrane _h_4526 blue BNIP3 _h_686 blue JUN_nucleus _h_687 blue Necdin_E2F1_nucleus red grey red _h_4784 blue YWHAZ__dimer__1act red grey _h_6227 blue VEGFA145__dimer__extracellular_region blue _h_4522 NF_kappa_B1_p50_RelA_1act_nucleus grey red blue _h_1556 ( not HES1_Myb_1act_nucleus) blue _h_4835 CBP_nucleus or p300_nucleus red red grey red grey red grey grey grey red blue _h_3939 FOXO3A_nucleus _h_5815 blue Cyclin_D1 grey blue _h_1979 GNB1_GNG2_1act_cytoplasm and not Gi_family_GTP_RGS1_1act_cytoplasm _h_161_2 blue CBP_nucleus _h_161_1 blue p300_nucleus blue _h_3937 cAMP red _h_4783 blue (E2_ERA_ERB__dimer__1act_plasma_membrane and Gq_family_GDP_Gbeta_gamma) grey red blue _h_3932 TAp63g__tetramer__1act_nucleus_v2 grey grey _h_522 blue alpha_Tubulin_beta_Tubulin grey grey blue _h_184 LMAN1 _h_1554 blue HGF_dimer__MET_dimer__1act_integral_to_membrane_v1 blue _h_6172_5 DAG_v2 red grey blue _h_3959_2 ROCK2_1act or ROCK_1act blue _h_3959_3 ROCK2_1act or ROCK_1act blue _h_3959_1 ROCK2_1act or ROCK_1act grey red _h_206 blue Ephrin_A1_EPHA2_1act_integral_to_membrane _h_4182 blue paxillin red grey grey grey red blue _h_1271_1 ((((HePTP or MEK1_1act_cytoplasm) or MEK1_2O_1act_cytoplasm) or MEK2_1act_cytoplasm) or PKC_theta_1act_plasma_membrane) red grey grey grey red grey grey grey grey grey red grey red grey red grey grey blue _h_4236 cIAP1_UbcH5C grey blue _h_200 TAp63g__tetramer__1act_nucleus_v2 grey grey grey red grey _h_3650_1 blue FOS_3O_1O_1act_nucleus and ICER1_nucleus and JUN_2O_1act_nucleus red red _h_27_3 blue Elf1_nucleus _h_27_2 blue Elf1_nucleus _h_27_1 blue Elf1_nucleus grey _h_6438_2 blue FAK_Src_Yes_Fyn_1act_focal_adhesion_v2_Src_1act_1O_FAK_6O_1act red blue _h_4621 PI_3_4_5_P3_plasma_membrane blue _h_5108 ((CBP_nucleus or MYC_Max_TRRAP_GCN5_STAF65G_SPT3_TAF9_TAF10_TAF12_core_Mediator_nucleus) or p300_nucleus) grey grey red red blue _h_5103 PLK1 grey grey blue _h_5104 dNp63b__tetramer__nucleus blue _h_5107 not FAK red grey blue _h_6138 nectin_3_dimer__I_afadin_I_afadin_nectin_3_dimer__I_afadin_I_afadin_cell_cell_junction grey grey red red grey red blue _h_6135 Src_1act_1O red _h_6137 blue RasGAP blue _h_6136 ((JUN_FOSNFAT1_c_4_1act_nucleus_c_Jun_2O_NFAT1_1O_7O_2s_1act_nucleus_FOS_1O_1O or JUN_FOSNFAT1_c_4_1act_nucleus_c_Jun_2O_NFAT4_1act_nucleus_FOS_1O_1O) or JUN_FOSNFAT1_c_4_1act_nucleus_c_Jun_2O_NFATc_1act_nucleus_FOS_1O_1O) grey grey grey grey grey blue _h_2083 p38_alpha_1O_1O_1act_v2 or p38_beta_1O_1O_1act red blue _h_203 ((ASPP or CSE1L_nucleus) or p53__tetramer__nucleus_v3) red red grey blue _h_2650 (p53__tetramer__nucleus_v2 and ( not HDAC2_nucleus)) _h_2651 blue p53__tetramer__nucleus_v2 grey blue _h_2653 p53__tetramer__nucleus_v2 blue _h_2654 (SP1 or STAT6__dimer__1act_nucleus_v1) blue _h_2656 GSK3beta blue _h_2657 FAK_1O_1act_focal_adhesion _h_3165 blue IL3_IL3RA_CSF2RB__dodecamer__integral_to_membrane grey red grey grey grey red blue _h_4951_1 Insulin_Receptor_Insulin_GRB14_PDK1 red red blue _h_5172 PLK1_1O_1act red red grey blue _h_3163 MKLP2_spindle red blue _h_139 not MYC_Max_nucleus_v4 red grey grey grey red grey grey grey grey red grey grey grey red red red red red red red grey grey red grey grey blue _h_807_64 FASLG_FAS__trimer__Src_Syk_1act_integral_to_membrane or TRAIL__trimer__extracellular_region grey red grey grey _h_1306 blue TRAF2 grey blue _h_2903 Arf6_GTP_1act or Phosphatidic_acid blue _h_2904 JUN_FOS_1act_nucleus_v4 red _h_1301 blue BAMBI and BMP2_4__homodimer__extracellular_region and BMPR1A_1B__homodimer__integral_to_membrane and BMPR2__homodimer__1act_integral_to_membrane and RGM_family grey blue _h_4574_16 EHD4_1act _h_2909 blue FGFR_FGF_Syndecan_2_FRS2_Sprouty2_1ina blue _h_4574_14 EHD4_1act blue _h_5122_1 (Ca2__cytoplasm or DAG_v2) blue _h_4574_12 EHD4_1act blue _h_4574_13 EHD4_1act red blue _h_4574_11 EHD4_1act blue _h_4762 TCF4_beta_catenin_1act_nucleus red red _h_4761 blue GTP_v1 and (CalDAG_GEFIII_1act or FAK_GRB2_SOS1_1act_cytoplasm or GRB2_SOS1_plasma_membrane or GRB2_SOS2_plasma_membrane or HGF_dimer__MET_dimer__GRB2_SOS1_1act_integral_to_membrane or HGF_dimer__MET_dimer__RANBP9_SOS1_1act_integral_to_membrane or HGF_dimer__MET_dimer__p52_SHC_GRB2_SOS1_1act_integral_to_membrane) _h_4766 blue TRF2 red grey grey _h_4769 blue DAT_cytoplasm and not Colchicine red grey blue _h_5771 PI_3_4_5_P3_plasma_membrane red grey grey grey blue _h_5774 (( not RASSF1A) and (HAUSP_DAXX or PCAF_nucleus)) grey grey grey red red grey blue _h_407 p53__tetramer__nucleus_v2 grey grey grey grey grey red grey grey red red grey grey blue _h_2434_34 ((EGFR_EGFR_1act_integral_to_membrane_v1 or EGFR_EGFR_EGF_EGF_GRB2_GAB1_1act_integral_to_membrane_v1) and ( not (EGFR_EGFR_1ina_integral_to_membrane or EGFR_EGFR_EGF_EGF_GRB2_GAB1_1ina_integral_to_membrane))) red blue _h_4192 PTP1B_1act or TCPTP_p45_1act or TCPTP_p45_integral_to_membrane _h_900 blue alphav_beta3_Integrin_integral_to_membrane grey grey red red grey red grey blue _h_745 not HES1_nucleus grey red blue _h_746 VEGFR3_VEGFC_D_1act_plasma_membrane _h_217 blue VEGFR2_integral_to_membrane blue _h_740 JUN_FOS_1act_nucleus_v4 _h_743 blue IL12Rbeta1_TYK2 and IL12Rbeta2_JAK2 and not IL4_extracellular_region and (IL1_beta or NOS2) _h_742 blue IL1_beta_fragment_IL1R1_IL1RAP_TICAM2_IRAK4_1act and TRAF6 _h_925_3 blue mTORC1_PRAS40_DEPTOR_1ina_cytoplasm_v1 red _h_218 blue GM_CSF_extracellular_region blue _h_749 PI_3_4_5_P3_plasma_membrane blue _h_748 HGF_dimer__MET_dimer__1act_integral_to_membrane_v1 or Insulin_Receptor_Insulin_1act_integral_to_membrane red red grey grey grey grey blue _h_1036_143 Arf6_GTP_1act or Arf6_GTP_1act_plasma_membrane blue _h_1036_142 Arf6_GTP_1act or Arf6_GTP_1act_plasma_membrane blue _h_1036_141 Arf6_GTP_1act or Arf6_GTP_1act_plasma_membrane _h_3232 blue PECAM1 _h_3235 blue GTP_v1 and not p27Kip1_1O and (ABR_1act or AKAP13_1act or ARHGEF10_1act or ARHGEF12_1act or ARHGEF17_1act or ARHGEF18_1act or ARHGEF2_1O_1act or ARHGEF2_1act or ARHGEF3_1act or ARHGEF5_1act or BCR_1act or CDEP_1act or DBL_1act or DBS_1act or DEF6_1act or ECT2_1act or Ephexin_1act_2O or GEFT_1act or GrinchGEF_1act or NET1_1act or OBSCN_1act or PDZRhoGEF_1act or TRIO_1act or VAV1_1act or VAV2_1act or Vav3_1act or VsmRhoGEF_1act or myoGEF_1act or p115RhoGEF_1act or p190RHOGEF_1act or smgGDS_1act) _h_3234 blue JUND_nucleus red blue _h_1036_144 Arf6_GTP_1act or Arf6_GTP_1act_plasma_membrane _h_3239 blue Filamin_A_C_terminal_fragment blue _h_3238 MEK1_2O_1act grey grey red grey blue _h_5688 CEBPA_nucleus or CEBPB_nucleus or CEBPD_nucleus or Myb_nucleus or SPI1_nucleus blue _h_5689 STAT5__dimer__1act_nucleus red _h_5687 blue PI3K blue _h_5684 SMAD2_SMAD2_SMAD4_FOXH1_1act_nucleus and not SMAD3_SMAD4_1act_nucleus _h_5685 blue RelA_nucleus grey grey _h_5680 blue RPL11 grey _h_2847 blue Syndecan_1 red red red red _h_4882 blue nectin_3_dimer__I_afadin_I_afadin_integral_to_membrane blue _h_4881 EGFR_EGFR_EGF_EGF_GNAI1_GNAI3_GAB1_1act_integral_to_membrane_v1 or EGFR_EGFR_EGF_EGF_GRB2_GAB1_1act_integral_to_membrane_v1 _h_4880 blue alpha3_beta1_Integrin_integral_to_membrane _h_4887 blue PLD2_1act blue _h_4885 caspase_3__cleaved__1act blue _h_4884 ATRA blue _h_6489 p53__tetramer__nucleus_v2 grey grey grey _h_3352 blue SMAD3_SMAD4_1act_nucleus _h_3353 blue CHD3_nucleus and HDAC_complex_nucleus_v1 and MBD2_nucleus and MBD3_nucleus and MTA2_nucleus and p66_alpha_nucleus and p66_beta_nucleus blue _h_3350 (E2F1_DP_nucleus_v4 and ( not E2F1_DP_TopBP1_nucleus)) blue _h_3351 MYC_Max_nucleus_v2 _h_6481 blue Fibronectin_extracellular_matrix blue _h_6480 (((((((((((((ASK1_ASK2_1act or CaM_Ca2__CAMKIIB_ASK1_1act) or FASLG_FAS__trimer__1act_integral_to_membrane) or GADD45_MTK1_MTK1) or MEKK1_2O_1act) or MLK2_1act) or MLK7_1act_1p) or PKA_1act) or TAK1_TAB_family_1act_v1_TAB1_TAK1_1act) or TAK1_TAB_family_1act_v1_TAB2_TAK1_1act) or TAO_family_active_1act) or TRAF2_ASK1_1act) or TRAF6_ASK1_1act) or TRAF6_TAK1_TAB1_TAB2_1act_cytoplasm_v3) blue _h_6483 Cyclin_B1_CDK1_1act_v2 grey grey _h_6306_2 blue EPHB1_integral_to_membrane blue _h_3358 dNp63a__tetramer__nucleus_v2 blue _h_6486 Digestive_enzymes_endosome red grey red grey blue _h_5978 Ca2__cytoplasm _h_5979 blue (LPS and TRAF6) grey _h_5970 blue COT_cytoplasm grey grey grey blue _h_5974 AKT2_1O_1O_1act_plasma_membrane or Akt1_1O_1O_1act_plasma_membrane or Akt1_1O_1act_1O_1O_plasma_membrane blue _h_5975 MgcRacGAP_1act or RAC1_GTP_1act_plasma_membrane grey red grey grey grey grey grey red grey _h_925_6 blue YWHAB _h_925_5 blue mTORC1_PRAS40_DEPTOR_1ina_cytoplasm_v1 _h_925_4 blue YWHAZ red _h_925_2 blue mTORC1_PRAS40_DEPTOR_1ina_cytoplasm_v1 _h_925_1 blue YWHAG grey grey red red blue _h_2405 ( not BCL2) grey blue _h_2404 GMCSF_GMR_alpha_CSF2RB_JAK2__dodecamer__SHC_SHIP_1act_integral_to_membrane or SHIP or SHIP2_1act_plasma_membrane or SHIP_1act_plasma_membrane or SHIP_2O_plasma_membrane _h_338 blue HGF_dimer__MET_dimer__1act_integral_to_membrane_v1 _h_2407 blue VCAM1 blue _h_2406 ceramide _h_6093_2 blue AP_2_adaptor_complex and beta_Arrestin2 grey grey _h_6093_1 blue AP_2_adaptor_complex and IL8_CXCR2_1act_integral_to_membrane_v2 blue _h_2401 MYC_Max_nucleus_v2 _h_765 blue PKC_alpha_1act or PKC_gamma_1act _h_5031 blue ((GTP_v1 and ( not Galectin3)) and ((((((((((((((Btk_1act_2O_plasma_membrane or Ca2__v1) or CaM) or CalDAG_GEFIII_1act) or DAG_v2) or Ephrin_B_EPHB1_1act_integral_to_membrane) or HGF_dimer__MET_dimer__1act_integral_to_membrane_v3) or RASGRF1_1act) or RASGRF1_1act_plasma_membrane) or RASGRF2_1act) or RASGRP1_1act) or RASGRP4_1act) or SHC_Grb2_SOS1_1act_v2) or T_DHT_AR_PELP1_Src_plasma_membrane) or VAV1_1act_1O)) red red _h_2151 blue alphaM_beta2_Integrin grey grey blue _h_763 (( not EGR2) and ((JUN_FOSNFAT1_c_4_1act_nucleus_c_Jun_2O_NFAT1_1O_7O_2s_1act_nucleus_FOS_1O_1O or JUN_FOSNFAT1_c_4_1act_nucleus_c_Jun_2O_NFAT4_1act_nucleus_FOS_1O_1O) or JUN_FOSNFAT1_c_4_1act_nucleus_c_Jun_2O_NFATc_1act_nucleus_FOS_1O_1O)) grey grey grey grey grey red red grey grey _h_1756 blue LPA2_plasma_membrane _h_4264_1 blue Erk2_1O_1O_1act_nucleus _h_2333 blue JUN_FOS_1act_nucleus_v2 blue _h_2332 MYC_Max_nucleus_v2 _h_2331 blue Synbindin _h_6341_3 blue beta_catenin blue _h_2337 ( not ((CBP or cortisol_GR_alpha__monomer__nucleus) or p300)) grey blue _h_2335 ATR_1act grey _h_2338 blue Erk1_1O_1act_1O_cytoplasm red _h_1492 blue E_cadherin_gamma_catenin_alpha_catenin_basolateral_plasma_membrane _h_2408 blue Estrogen_receptor_alpha red _h_53 blue Cone_Transducin_1ina blue _h_5904 N_cadherin_Ca2__p120_catenin_beta_catenin_gamma_catenin_alpha_catenin_cell_cell_junction grey grey red _h_3272 blue PINCH1 and PINCH2 and alpha_parvin blue _h_3826 ((STAT5A_B__dimer__1act_nucleus or STAT5A__dimer__active_1act_nucleus_v2) or STAT5B__dimer__1act_nucleus) _h_51 blue VEGFR2_integral_to_membrane and VEGFR3_integral_to_membrane grey _h_3821 blue Filamin_A_C_terminal_fragment _h_2009 blue LRP1 _h_3823 blue GRB2 and PTP1B_plasma_membrane _h_56 blue HDAC4_nucleus and SMRT__N_CoR2_ _h_4339 blue RGS3 _h_3829 blue SMAD5_2O_1act_cytoplasm grey grey blue _h_3751 Cables or PML grey grey blue _h_4496 alphaV_beta3_Integrin_Osteopontin grey blue _h_1036_38 Arf6_GTP_1act or Arf6_GTP_1act_plasma_membrane _h_5965_1 blue PTEN_v2 grey _h_5965_2 blue PDGF_BB_PDGFRB__dimer__NHERF1_2_1act_integral_to_membrane_PDGFRB_11O_NHERF1_PDGFB_v1 red blue _h_2484 WNT3A_FZD5_LRP6_1act_integral_to_membrane red red _h_2481 blue ErbB2_integral_to_membrane and epiregulin_extracellular_region red red _h_2482 blue uPA_uPAR_alphav_beta3_Integrin_1act_integral_to_membrane grey red blue _h_3756 (TAp63g__tetramer__1act_nucleus_v3 and ( not TAp63g__tetramer__p14ARF_1ina_nucleus)) grey red grey red blue _h_2454 PTP1B_plasma_membrane red grey _h_1178 blue ER_alpha_nucleus red grey grey grey _h_5309_6 blue Laminin_8 blue _h_6415 mTORC1_PGC1A_YY1_1act_nucleus _h_3669 blue CD4 and Monovalent_TCR_CD3_1ina_integral_to_membrane blue _h_1036_32 Arf6_GTP_1act or Arf6_GTP_1act_plasma_membrane grey red grey grey red red grey red blue _h_1682 p53__tetramer__nucleus_v2 blue _h_1683 ((JUN_FOSNFAT1_c_4_1act_nucleus_c_Jun_2O_NFAT1_1O_7O_2s_1act_nucleus_FOS_1O_1O or JUN_FOSNFAT1_c_4_1act_nucleus_c_Jun_2O_NFAT4_1act_nucleus_FOS_1O_1O) or JUN_FOSNFAT1_c_4_1act_nucleus_c_Jun_2O_NFATc_1act_nucleus_FOS_1O_1O) blue _h_1680 FA_core_complex_chromatin or UAF1_USP1_chromatin blue _h_1681 AR_T_DHT_nucleus or SRF blue _h_1686 not MYC_Max_nucleus_v4 red red blue _h_1689 FGFR_FGF_Syndecan_2_1act grey _h_2078 blue Aurora_A and ILK_centrosome and TACC3 blue _h_2298 MYC_Max_TRRAP_GCN5_STAF65G_SPT3_TAF9_TAF10_TAF12_core_Mediator_nucleus _h_4335 blue alpha3_beta1_Integrin_integral_to_membrane grey grey _h_5011 blue Aurora_B blue _h_3755 PKN_1act blue _h_5010 ( not RXRs_PPAR_9cRA_PGJ2_DNA) grey grey grey blue _h_3970_5 ETA_receptor_Endothelin_1_Gs_GTP_1act_integral_to_membrane or PKC_epsilon_1act_cytoplasm red blue _h_5379 PDGF_BB_PDGFRB__dimer__alphav_beta3_Integrin_Necl_5__dimer__1act_cell_leading_edge _h_5376 blue E2_nucleus and ER_alpha_nucleus blue _h_5377 ( not (DHT_plasma_membrane or testosterone_plasma_membrane)) red blue _h_5375 EGF_EGFR_1act or H2O2 or Insulin_Receptor_Insulin_1act or NADPH or NOX4 or thioredoxin blue _h_5372 (PAX3_nucleus and ( not RB1_nucleus)) blue _h_5373 CDC42_GTP_1act_plasma_membrane or RAC1_GTP_1act_plasma_membrane red _h_5371 blue p53_1act_6N_nucleus grey grey blue _h_1468 MgcRacGAP_1act or RAC1_GTP_1act_plasma_membrane blue _h_2291 NF_kappa_B1_RelA_1act_nucleus _h_1466 blue Crk and RAC1_GTP_1act_plasma_membrane blue _h_1467 TCF4E_beta_catenin_BCL9_1act_nucleus blue _h_6304 DMN1_GTP_1act or EPS15_plasma_membrane grey _h_1462 blue GTP_v1 and VAV2_1O_1act_cell_cell_junction red grey blue _h_1461 PSD95 blue _h_5051_18 (RAS_family_GTP_1act_plasma_membrane_H_RAS_isoform_1_GTP_v1 or RAS_family_GTP_1act_plasma_membrane_N_RAS_GTP_v1) blue _h_1286 NCKX1 or NCKX2__SLC24A2_ blue _h_2293 Src_1O_1act_cell_cell_junction grey _h_5449 blue PTCH1_integral_to_membrane red grey grey grey grey grey red red blue _h_807_68 FASLG_FAS__trimer__Src_Syk_1act_integral_to_membrane or TRAIL__trimer__extracellular_region red red grey blue _h_50 FIH__dimer_ blue _h_2297 p53__tetramer__nucleus_v2 red blue _h_4336 MYC_Max_nucleus_v2 red _h_1280 blue TERT grey _h_4271 blue ARHGAP10_cytosol blue _h_1281 FAK_1O_1act_cell_cell_junction red _h_5440 blue alpha3_beta1_Integrin_1act_integral_to_membrane _h_4902 blue Laminin_6_basement_membrane grey _h_4331 blue DAB1 and RELN_VLDLR_Fyn and not Src_family_inhibitors_PP1_and_PP2 grey _h_1926 blue LINGO1 and NGR and p75_NTR__1N_integral_to_membrane blue _h_2434_3 ((EGFR_EGFR_1act_integral_to_membrane_v1 or EGFR_EGFR_EGF_EGF_GRB2_GAB1_1act_integral_to_membrane_v1) and ( not (EGFR_EGFR_1ina_integral_to_membrane or EGFR_EGFR_EGF_EGF_GRB2_GAB1_1ina_integral_to_membrane))) blue _h_2434_2 ((EGFR_EGFR_1act_integral_to_membrane_v1 or EGFR_EGFR_EGF_EGF_GRB2_GAB1_1act_integral_to_membrane_v1) and ( not (EGFR_EGFR_1ina_integral_to_membrane or EGFR_EGFR_EGF_EGF_GRB2_GAB1_1ina_integral_to_membrane))) blue _h_2434_1 ((EGFR_EGFR_1act_integral_to_membrane_v1 or EGFR_EGFR_EGF_EGF_GRB2_GAB1_1act_integral_to_membrane_v1) and ( not (EGFR_EGFR_1ina_integral_to_membrane or EGFR_EGFR_EGF_EGF_GRB2_GAB1_1ina_integral_to_membrane))) _h_5443 blue PKC_zeta_1act blue _h_2434_7 ((EGFR_EGFR_1act_integral_to_membrane_v1 or EGFR_EGFR_EGF_EGF_GRB2_GAB1_1act_integral_to_membrane_v1) and ( not (EGFR_EGFR_1ina_integral_to_membrane or EGFR_EGFR_EGF_EGF_GRB2_GAB1_1ina_integral_to_membrane))) blue _h_2434_6 ((EGFR_EGFR_1act_integral_to_membrane_v1 or EGFR_EGFR_EGF_EGF_GRB2_GAB1_1act_integral_to_membrane_v1) and ( not (EGFR_EGFR_1ina_integral_to_membrane or EGFR_EGFR_EGF_EGF_GRB2_GAB1_1ina_integral_to_membrane))) blue _h_2434_5 ((EGFR_EGFR_1act_integral_to_membrane_v1 or EGFR_EGFR_EGF_EGF_GRB2_GAB1_1act_integral_to_membrane_v1) and ( not (EGFR_EGFR_1ina_integral_to_membrane or EGFR_EGFR_EGF_EGF_GRB2_GAB1_1ina_integral_to_membrane))) red red blue _h_2434_8 ((EGFR_EGFR_1act_integral_to_membrane_v1 or EGFR_EGFR_EGF_EGF_GRB2_GAB1_1act_integral_to_membrane_v1) and ( not (EGFR_EGFR_1ina_integral_to_membrane or EGFR_EGFR_EGF_EGF_GRB2_GAB1_1ina_integral_to_membrane))) blue _h_4903 Arf6_GTP_1act_plasma_membrane or PI_4_5_P2_plasma_membrane _h_5769 blue CDC42_GTP_1act_cell_cell_junction blue _h_5768 Tie2_Ang1_1act grey blue _h_5765 (( not HDAC2_nucleus) and (TRRAP_nucleus or p53__tetramer__nucleus_v2)) grey grey red blue _h_5761 p53__tetramer__nucleus_v2 blue _h_5760 FOXA2_nucleus_v1 _h_5763 blue SMAD3_SMAD4_1act_nucleus grey _h_6258 blue FKBP12_TGFBR1__dimer__1ina_integral_to_membrane and TGFB1_TGFBR2_Endoglin__dimer__1act_integral_to_membrane grey blue _h_328 SMO_1act_nonmotile_primary_cilium grey red grey grey grey _h_5804_2 blue FRS2_family_SHP2_1act and (BDNF__dimer__TRKB_1act_endosome_v2 or NGF__dimer__TRKA_1act_endosome or NT3__dimer__TRKC_1act_endosome or NT_4_5__dimer__TRKB_1act_endosome) grey grey grey blue _h_910 FOXA1_nucleus blue _h_911 LEF1_beta_catenin_1act_nucleus_v2 _h_912 blue GAS1_1N grey _h_914 blue (PTP1B_1ina and p130Cas_1O) blue _h_915 DHT_AR_nucleus or FOXA1_nucleus blue _h_916 (HES1_PARP1_Cbp_1act_nucleus and ( not HES1_TLE1_PARP1_1act_nucleus)) blue _h_917 MYC_Max_nucleus_v2 red red _h_399_2 blue SMAD4_cytoplasm grey blue _h_1036_124 Arf6_GTP_1act or Arf6_GTP_1act_plasma_membrane _h_4647_1 blue PDE3B_1act grey grey blue _h_5051_17 (RAS_family_GTP_1act_plasma_membrane_H_RAS_isoform_1_GTP_v1 or RAS_family_GTP_1act_plasma_membrane_N_RAS_GTP_v1) blue _h_1571 TAp73a__tetramer__nucleus_v3 _h_4756_2 blue IL8_CXCR1_beta_Arrestin1_2_1act_integral_to_membrane_CXCR1_1p_beta_Arrestin2_IL8 grey grey blue _h_1572 Blk_1O_1act_plasma_membrane or Fgr_1act_1O_plasma_membrane or Fyn_1O_1act or Fyn_1act_1O_plasma_membrane or Hck_1act_1O_plasma_membrane or LYN_1O_1act_plasma_membrane or LYN_1act_1O or Lck_1O_1act or Lck_1O_1act_plasma_membrane or Src_1O_1act_plasma_membrane or Src_1act_1O or Yes_1act_1O_plasma_membrane grey grey blue _h_4275 (Cbp_p300_MSG1_nucleus_MSG1_CBP_nucleus or Cbp_p300_MSG1_nucleus_MSG1_p300_nucleus or Cbp_p300_PIAS3_PIAS3_CBP or Cbp_p300_PIAS3_PIAS3_p300) and not (Cbp_p300_SNIP1_nucleus_CBP_nucleus_SNIP1 or Cbp_p300_SNIP1_nucleus_p300_nucleus_SNIP1 or MSG1_HSC70 or SKI_SIN3_HDAC_complex_NCoR1 or TGIF_SIN3_HDAC_complex_CtBP) red grey red blue _h_6254 Jak2_1act or Src_1act_1O red grey red _h_1575 blue Ephrin_B_EPHB2_1act_integral_to_membrane _h_2562 blue I_kappa_B_alpha_nucleus blue _h_5051_16 (RAS_family_GTP_1act_plasma_membrane_H_RAS_isoform_1_GTP_v1 or RAS_family_GTP_1act_plasma_membrane_N_RAS_GTP_v1) blue _h_1576 Antigen_IgE_Fc_epsilon_R1_LYN_SYK_v2 grey red blue _h_1992 RHOA_GTP_1act_cell_cell_junction blue _h_1577 alphav_beta3_Integrin_Tumstatin grey grey blue _h_4276 (AR_T_DHT_nucleus or BRCA1) red red grey red _h_2566 blue DKK1_extracellular_region and FZD1_integral_to_membrane and WNT1_extracellular_region grey blue _h_1777 MYC_Max_nucleus_v2 blue _h_5051_11 (RAS_family_GTP_1act_plasma_membrane_H_RAS_isoform_1_GTP_v1 or RAS_family_GTP_1act_plasma_membrane_N_RAS_GTP_v1) blue _h_3593 p38_alpha_1O_1O_1act_v2 or p38_beta_1O_1O_1act grey _h_1993 blue PDE6A_B_1act and RGS9_1_Gbeta5_R9AP red grey blue _h_3595 TAp63g__tetramer__1act_nucleus_v2 red blue _h_4418 dNp63a__tetramer__nucleus_v2 grey _h_5415 blue CDX1_nucleus blue _h_4904 CBL_1O_1act or UBCH5 or UbcH5C blue _h_4414 PRL_1 or PRL_3 blue _h_4415 not FAP1 _h_4416 blue NF_kappa_B2_p100_cytoplasm grey _h_4410 blue Talin_cell_cell_junction grey blue _h_4412 E_cadherin_Ca2__beta_catenin_gamma_catenin_alpha_catenin_p120_catenin_cell_cell_junction_v2 blue _h_4413 p53__tetramer__nucleus_v2 blue _h_5051_10 (RAS_family_GTP_1act_plasma_membrane_H_RAS_isoform_1_GTP_v1 or RAS_family_GTP_1act_plasma_membrane_N_RAS_GTP_v1) blue _h_2741_1 TGFB_TGFBR2_TGFBR1_DAB2_1act_integral_to_membrane grey grey _h_5909 blue PLCgamma1_3O_1act_growth_cone red grey red red blue _h_5950 CDC42_GTP_1act_plasma_membrane or RAC1_GTP_1act_plasma_membrane red red grey red red red red grey grey blue _h_5954 Axin1_GSK3beta_PIN1_PP2A_B56alpha grey _h_2858 blue GRB2_cytoplasm and PAK4 blue _h_546 not MYC_Max_RPL11_nucleolus and (CBP_nucleus or MYC_Max_TRRAP_TIP60_TIP49A_TIP49B_BAF53_nucleus or p300_nucleus) red grey red blue _h_3596 p210_bcr_abl red grey red red grey grey grey red grey blue _h_5505 (p38_alpha_1O_1O_1act_v2 or p38_beta_1O_1O_1act) grey grey _h_5504 blue Erk2_1O_1O_1act blue _h_6063 ((AR_T_DHT_nucleus or FHL2) or PELP1) _h_6019_2 blue MNK1 red grey grey _h_4808_3 blue PLCgamma1 red red blue _h_544 TAp63a__tetramer__1act_nucleus_v2 red red blue _h_3598 IL2_IL2R_beta_gamma_JAK1_LCK_JAK3_1act_integral_to_membrane grey grey grey grey blue _h_2791 Erk1_1O_1act_1O_nucleus or Erk2_1O_1O_1act_nucleus grey grey blue _h_1884_2 BRAF_1act or RAF1_1O_1O_1act_cytoplasm or RAF1_1O_1act_v1 or RAF1_1act grey _h_497_2 blue (DHT_cytoplasm and HDJ2) red _h_5162 blue PI3K_cytoplasm _h_5161 blue PI_4_5_P2_plasma_membrane blue _h_5160 E2F1_3_DP_DP1_E2F1 or E2F1_3_DP_DP1_E2F2 or E2F1_3_DP_DP1_E2F3 or SP1_3_nucleus or p53__tetramer__nucleus_v2 blue _h_5167 (RBPJ_NICD_MAML1_2_p300_1act_nucleus and ( not SHARP_RBPJ_nucleus)) blue _h_5166 STAT1__dimer__1act_nucleus_v4 _h_5165 blue ET1_extracellular_region _h_5164 blue EPHB4_integral_to_membrane red red blue _h_5169 Importin_beta or importin_alpha grey blue _h_6153 Myb_nucleus _h_6152 blue PKA_1act _h_6151 blue PER1_2___CRY1_2_cytoplasm blue _h_6150 ARF4_GTP_1act_plasma_membrane or PKC_beta_1act_plasma_membrane or PKC_isoenzymes_1act_plasma_membrane or PRKCG_1act_plasma_membrane red blue _h_6156 (PDGF_BB_PDGFRB__dimer__1act_integral_to_membrane_v1 or nectin_3_dimer__I_afadin_I_afadin_nectin_3_dimer__I_afadin_I_afadin_cell_cell_junction) blue _h_6155 beta_TrCP1_SCF_ubiquitin_ligase_complex_cytoplasm blue _h_6154 FIH__dimer_ or HIF1A_1O_cytoplasm red red blue _h_6158 Src_1act_1O red red red grey red red blue _h_4827 FGFR_FGF_Syndecan_2_1act red grey grey grey grey grey grey grey _h_2498_2 blue ((RAS_family_GDP_Aiolos_1ina_plasma_membrane_N_RAS_Aiolos_1ina_GDP_v1 and ( not RasGAP_Dok_R_1act)) and (IL2_IL2R_alpha_beta_gamma_JAK1_LCK_JAK3_SHC_GRB2_SOS1_GAB2_1act_integral_to_membrane or SOCS3_RasGAP_1act)) red grey red red red red grey grey grey grey grey red grey blue _h_4821 PP2A_v2 grey grey grey grey grey grey blue _h_6199 SMAD3_SMAD4_SP1_1act_nucleus grey _h_5019 blue Pellinos or UBC13_UEV1A grey blue _h_1096 p53__tetramer__nucleus_v2 _h_1095 blue ETA red grey _h_1092 blue GRB2 blue _h_1091 (JUN_JUN_FOS_1act_nucleus_v2_JUN or JUN_JUN_FOS_1act_nucleus_v2_JUN_FOS) grey red grey grey _h_5413 blue E2_ER_alpha__dimer__PELP1_Src_1act_caveola_v1 red red grey blue _h_1036_140 Arf6_GTP_1act or Arf6_GTP_1act_plasma_membrane grey red red grey grey _h_2672 blue alpha6_beta1_Integrin_integral_to_membrane grey blue _h_2671 (AR_T_DHT_nucleus and ( not TGIF)) grey grey grey grey red _h_2678 blue Ca2__CaM_1act blue _h_2679 Fra1_JUN_1act_nucleus grey blue _h_1321 (SMAD3_SMAD4_SP1_1act_nucleus and ( not SMAD3_SMAD4_ER_alpha_1act_nucleus)) red grey grey _h_1325 blue PI3K blue _h_1324 not MYC_Max_nucleus_v4 _h_1327 blue SHC_cytoplasm red red grey grey _h_2921 blue alpha4_beta1_Integrin_integral_to_membrane_v1 red blue _h_2927 CREB1_1O_1act _h_2924 blue HMGB1_extracellular_region and alphaM_beta2_Integrin grey red blue _h_4788 p53__tetramer__nucleus_v2 blue _h_4789 ETA_receptor_Endothelin_1_integral_to_membrane or GRB10_1act_plasma_membrane or PDK1_1O_1act_plasma_membrane _h_6447_1 blue BRM_nucleus blue _h_4785 LEF1_beta_catenin_1act_nucleus_v1 red grey _h_4780 blue TCRz blue _h_4781 TAp73b__tetramer__nucleus red red _h_5939 blue LRP1 and tPA _h_5115 blue Laminin_11_basement_membrane blue _h_448 Jnk1_1O_1act_1O grey blue _h_997 TAp73b__tetramer__nucleus red grey grey blue _h_54 (JUN__dimer__1act_nucleus_v1 or cortisol_GR_alpha__dimer__nucleus_v4) grey grey blue _h_447 Antigen_IgE_Fc_epsilon_R1_LYN_SYK_v2 red red red _h_444 blue Del1 blue _h_583 PLCgamma1_3O_1act_cytoplasm blue _h_582 RAB11A_GTP_1act blue _h_581 SMAD4_SMAD1_5_8__dimer__1act_nucleus red red _h_586 blue alphav_beta3_Integrin_integral_to_membrane blue _h_584 (( not (RET51_GFRalpha1_GDNF_DOK_RasGAP_NCK or SHC_SHIP)) and (((((((((((((EGF_EGFR_1act or ErbB2) or GNAI1_1act) or GNAI2_1act) or GNAI3_1act) or GNAO1_1act) or GNAZ_1act) or GNB1_GNG2_1act_cytoplasm) or IGF_1R_heterotetramer_IGF1_GRB2_Sos_Shc) or IGF_1R_heterotetramer_IGF1_IRS1_GRB2_Sos_caveola) or Insulin_Receptor_Insuli_IRS1_GRB2_SHC_Sos) or Insulin_Receptor_Insulin_SHC_GRB2_Sos1) or RET51_GFRalpha1_GDNF_DOK1) or alpha6_beta4_Integrin)) red blue _h_588 (AR_T_DHT_nucleus or Oct_1) red _h_455_5 blue BRAF_14_3_3_1act_plasma_membrane_YWHAQ_BRAF_1O_2O blue _h_2854 CEBPA_nucleus or CEBPB_nucleus or CEBPD_nucleus or Myb_nucleus red red grey blue _h_2908 PI3K_1act_plasma_membrane_v2 _h_455_3 blue BRAF_14_3_3_1act_plasma_membrane_BRAF_1O_2O_YWHAZ grey grey grey blue _h_3785 dNp63a__tetramer__nucleus_v2 _h_3784 blue p70S6K_3O_4O _h_3787 blue MEKK3 _h_3786 blue ABR_1act or ARHGAP17_1act or ARHGAP9_1act or BCR_1act or GRIT1_1act or MgcRacGAP_1act or N_chimerin_1act or RALBP1_1act or RHOGAP_1act or beta_2_chimerin_1act blue _h_3789 MKK4_1O_1O_1act or PKC_zeta_ceramide blue _h_3788 Gamma_Secretase_plasma_membrane_v2 grey grey grey grey grey red grey red grey _h_769 blue LRP6_FZD1 and not WNT_inhibitory_factor_1_extracellular_region _h_768 blue NF_kappa_B_RelA_1act_nucleus_v1 and OCT2 _h_767 blue CBL_plasma_membrane and betaPIX_1O_1act grey grey red grey grey grey grey blue _h_4912 (E2F1_DP_nucleus_v4 and ( not (E2F7_nucleus or E2F8_nucleus))) red red blue _h_3259 STAT1__dimer__1act_v1 blue _h_3258 FOXA2_nucleus_v1 grey _h_3253 blue BDNF__dimer__TRKB_1act_integral_to_membrane_v2 _h_3252 blue HDAC1_nucleus _h_3251 blue TopBP1 grey blue _h_3257 IL23_IL23R_JAK2_TYK2_1act_integral_to_membrane blue _h_3256 GSK3beta_cytoplasm red blue _h_3254 Fer_1act_1O_cell_cell_junction or N_cadherin_Ca2__beta_catenin_alpha_catenin_p120_catenin_Fer_cell_cell_junction grey grey red red grey grey blue _h_5699 ITCH_1act or NEDD4 red blue _h_3771 IRSP53 or PI_3_4_5_P3_plasma_membrane or RAC1_GTP_1act_plasma_membrane or c_Abl_1act_1O grey grey grey blue _h_3330 SCF_KIT_1act red red blue _h_3333 p38alpha_beta_MAPKAPK2_1act_MAPKAPK2_4O_1O_p38_alpha_1O_1O_1act_v2 or p38alpha_beta_MAPKAPK2_1act_MAPKAPK2_4O_1O_p38_beta_1O_1O_1act blue _h_3334 not TCPTP_p45_1ina_nucleus and (PTP1B or TCPTP_p45_integral_to_membrane) red _h_3336 blue BLNK _h_3338 blue 9cRA and PKA_1act _h_3339 blue beta_catenin_1O_cytoplasm_v2 and beta_catenin_cytoplasm _h_3631 blue CEBPB and HSF2 _h_847 blue VEGFR2__dimer__VEGFA__dimer__Src_1act_integral_to_membrane_v2 blue _h_5952 p53__tetramer__nucleus_v2 grey grey blue _h_5951 RDH12_plasma_membrane _h_5956 blue alpha6_beta4_Integrin_1act_integral_to_membrane grey grey blue _h_5955 FOXA2_nucleus_v1 red red blue _h_5958 Cyclin_B1_CDK1_1act_v1 blue _h_5959 STAT3__dimer___1act_nucleus grey grey grey grey blue _h_3444 DEP1_1act grey blue _h_3773 RhoA_1act grey grey red blue _h_3443 FOXA1_nucleus and not FOXA2_nucleus_v1 red grey grey grey _h_3441 blue HIF1A_nucleus and JAB1_nucleus blue _h_6436 LPA_LPA1_2_3_LPA1_plasma_membrane_LPA or LPA_LPA1_2_3_LPA2_plasma_membrane_LPA or LPA_LPA1_2_3_LPA3_plasma_membrane_LPA red grey grey _h_2611 blue Shelterin_Complex red grey red red grey grey red grey grey red grey red _h_1254 blue alpha9_beta1_Integrin_integral_to_membrane grey grey grey red blue _h_6337_2 ((BMP9_ACTR2_Endoglin_ALK1__dimer__1act_integral_to_membrane or BMP9_BMPR2_Endoglin_ALK1__dimer__1act_integral_to_membrane) or BMP9_BMPR2_Endoglin_ALK1__dimer__CK2B_1act_integral_to_membrane) blue _h_6337_1 ((BMP9_ACTR2_Endoglin_ALK1__dimer__1act_integral_to_membrane or BMP9_BMPR2_Endoglin_ALK1__dimer__1act_integral_to_membrane) or BMP9_BMPR2_Endoglin_ALK1__dimer__CK2B_1act_integral_to_membrane) red red red grey red red red red red grey blue _h_2761_2 (( not TGFB1_TGFBR2_Endoglin_TGFBR1_ALK1_PPP1CA_1act_integral_to_membrane) and ((((BMP7_BMPR2_ALK2__dimer__1act_integral_to_membrane or MIS_MISR2_ALK2__dimer__1act_integral_to_membrane) or TGFB1_TGFBR2_Endoglin_TGFBR1_ALK1_CAV1_1act_caveola) or TGFB1_TGFBR2_Endoglin_TGFBR1_ALK1_CK2B_1act_integral_to_membrane) or TGFB3_TGFBR2_Endoglin_TGFBR1_ALK1_1act_integral_to_membrane)) blue _h_2318 IKK_alpha_homodimer_1act_cytoplasm or NIK_1act_cytoplasm blue _h_2761_1 (( not TGFB1_TGFBR2_Endoglin_TGFBR1_ALK1_PPP1CA_1act_integral_to_membrane) and ((((BMP7_BMPR2_ALK2__dimer__1act_integral_to_membrane or MIS_MISR2_ALK2__dimer__1act_integral_to_membrane) or TGFB1_TGFBR2_Endoglin_TGFBR1_ALK1_CAV1_1act_caveola) or TGFB1_TGFBR2_Endoglin_TGFBR1_ALK1_CK2B_1act_integral_to_membrane) or TGFB3_TGFBR2_Endoglin_TGFBR1_ALK1_1act_integral_to_membrane)) _h_2315 blue ErbB3 and epiregulin_extracellular_region red grey blue _h_2316 N_WASP_1act or WAVE1_Sra1_Nap1_HSPC300_ABI2_1act_plasma_membrane or WAVE2_Nap1_Sra1_ABI1_HSPC300_1act_plasma_membrane blue _h_2310 ((BMP2_4_BMPR2_BMPR1A_1B_RGM_1act_integral_to_membrane or BMP6_BMPR2_BMPR1A_1B_1act) or PPM1A) blue _h_2313 ER_alpha_Gai_GDP_Gbeta_gamma_1act_plasma_membrane red red red red red red grey red red red blue _h_5790 CDK2_Cyclin_A_nucleus or Cyclin_G1_PP2A_Bprime red blue _h_5230 TAp73a__tetramer__nucleus_v3 grey _h_3808 blue ADAM15 _h_3806 blue NGF__dimer__TRKA_1act_integral_to_membrane and PI3K_PIKE_GTP_1act_nucleus grey red grey grey grey blue _h_3800 not MYC_Max_nucleus_v4 red grey _h_669 blue EGFR_integral_to_membrane and HB_EGF_extracellular_region _h_5235 blue E2_integral_to_membrane red grey red red red red red red blue _h_1573 mTORC1_1act grey red grey red red blue _h_190 B7_family_CD28_1act_integral_to_membrane_v2 red red grey grey _h_3779 blue Nemo_like_kinase_SETDB1_CHD7_1act red _h_5792 blue alphav_beta3_Integrin_integral_to_membrane grey grey grey blue _h_194 (CDC42_GTP_1act_plasma_membrane or RAC1_GTP_1act_plasma_membrane) blue _h_195 Fra2_JUN_1act_nucleus_v2 _h_6023 blue PTP1B_plasma_membrane grey grey _h_6022 blue uPAR_alphaM_beta2_Integrin_integral_to_membrane blue _h_2319 (IL1_beta or NF_kappa_B1_p50_RelA_I_kappa_B_alpha_1act_cytoplasm_v2) red blue _h_2761_3 (( not TGFB1_TGFBR2_Endoglin_TGFBR1_ALK1_PPP1CA_1act_integral_to_membrane) and ((((BMP7_BMPR2_ALK2__dimer__1act_integral_to_membrane or MIS_MISR2_ALK2__dimer__1act_integral_to_membrane) or TGFB1_TGFBR2_Endoglin_TGFBR1_ALK1_CAV1_1act_caveola) or TGFB1_TGFBR2_Endoglin_TGFBR1_ALK1_CK2B_1act_integral_to_membrane) or TGFB3_TGFBR2_Endoglin_TGFBR1_ALK1_1act_integral_to_membrane)) grey grey red grey grey red grey grey blue _h_1668 CaM_Ca2__Calcineurin_A_alpha_beta_B1_1act_v2 blue _h_1669 NFAT1_1O_4O_2s_1act_nucleus grey grey blue _h_1664 p53__tetramer__nucleus_v2 blue _h_1666 ( not dNp73a__tetramer__nucleus_v2) grey blue _h_1660 Fc_gamma_RIIa or PTP1B_plasma_membrane _h_2317 blue CD40_integral_to_membrane _h_1662 blue AR_T_DHT_plasma_membrane blue _h_1663 S1P_S1P2_Gi or S1P_S1P3_Gi blue _h_3763 SDF1_CXCR4_1act_integral_to_membrane grey red red blue _h_1213 ERK5_1act_nucleus blue _h_5382 PLCgamma1_2O_1act_plasma_membrane or RELN_LRP8 grey red grey blue _h_3767 IL1_alpha red grey _h_5318 blue MATK red blue _h_4699 MARK2 grey grey _h_5310 blue PKC_epsilon_Par3_Par6 grey _h_5312 blue Channel and Lethal_toxin__unfolded__endosome blue _h_5313 JUN_CREB1_1act_nucleus _h_5314 blue (AKAP1 and VEGFR2__dimer__VEGFA__dimer__1act_integral_to_membrane_v4) blue _h_5315 PRL_3 blue _h_5316 p53__tetramer__nucleus_v2 blue _h_5317 alpha4_beta1_Integrin_integral_to_membrane_v1 _h_6368 blue EGFR_EGFR_EGF_EGF_1act_integral_to_membrane_v1 and NHE1_integral_to_membrane _h_1409 blue KLRG1_1act red grey blue _h_6360 p38_delta_1O_1act_1O grey _h_1402 blue beta_catenin_nucleus and (_alpha_2__beta_2CK2_1act or _alpha___alpha_prime___beta_2_CK2_1act or _alpha_prime_2__beta_2_CK2_1act) grey blue _h_6364 Akt1_1O_1act_plasma_membrane_v2 blue _h_1405 cAMP blue _h_6366 ROCK2_1act or ROCK_1act blue _h_1407 T_DHT_AR_ARA70_nucleus red red red grey grey red grey red red red red grey red grey red grey grey grey grey red grey blue _h_5899_68 ErbB2_ErbB3_neuregulin_1_beta_1act_integral_to_membrane_v1 grey blue _h_4676 SRF_dimer__MAL_dimer__SCAI_1act_nucleus red red grey red grey _h_4907 blue paxillin _h_224 blue S1P_lyase1 or pyridoxal_5_prime_phosphate blue _h_6336 dNp63a__tetramer__nucleus_v2 blue _h_4672 FANCM_FAAP24_MHF1_MHF2_chromatin grey red blue _h_4673 TAp63a__tetramer__1act_nucleus_v3 blue _h_4683_8 GNAI1_1act or GNAI2_1act or GNAI3_1act or GNAO1_1act or GNAZ_1act _h_972 blue Rap1_GTP_I_afadin_cell_cell_junction and p120_catenin_cytoplasm grey blue _h_4045 dNp63a__tetramer__nucleus_v2 _h_4044 blue Tenascin_C_v3 _h_4043 blue SMAD4_cytoplasm _h_977 blue ((((BMP2_4__homodimer__extracellular_region and BMPR1A_1B__homodimer__integral_to_membrane) and BMPR2__homodimer__1act_integral_to_membrane) and CHRDL1) and RGM_family) grey blue _h_4040 RIN1 or Rabex5 grey grey _h_978 blue TCF4_TLE2_1act_nucleus _h_5177 blue HMGB1_TLR4_MD2__dimer__1act_integral_to_membrane grey blue _h_4049 not (HES1_nucleus or YY1) _h_4048 blue Syndecan_1 grey blue _h_2487 E2F1_1act_nucleus grey red grey grey _h_3804 blue Nap1 and RAC1_GTP_1act_cell_cell_junction and Sra1 blue _h_4702_2 Akt1_1O_1O_1act _h_761_1 blue alpha_actinin_1O_cytoplasm and alpha_actinin_cytoplasm grey grey grey _h_3802 blue FZD7 red _h_3803 blue E2_ERA__dimer__TIF2_1act_nucleus grey red grey grey blue _h_1373_2 GNB1_GNG2_1act_cytoplasm grey grey grey red grey blue _h_2114 (((BRAF_1O_1act_plasma_membrane or KSR_1act_plasma_membrane) or RAF1_4O_1act_plasma_membrane) or RAF1_BRAF_1act_v1) red red grey grey red grey _h_6143 blue not CENTA1_KIF3B_plasma_membrane and (CENTA1_1act_plasma_membrane or PI_3_4_5_P3_plasma_membrane) grey red _h_6145 blue Thrombin_PAR3_integral_to_membrane grey grey grey grey red grey grey grey blue _h_4434 (RELN_LRP8_DAB1 or RELN_VLDLR_DAB1) red grey grey _h_4430 blue uPA_uPAR_1act_plasma_membrane_v2 blue _h_391 dNp63a__tetramer__nucleus_v2 grey grey red blue _h_4439 CBP or PCAF or p300 blue _h_2434_22 ((EGFR_EGFR_1act_integral_to_membrane_v1 or EGFR_EGFR_EGF_EGF_GRB2_GAB1_1act_integral_to_membrane_v1) and ( not (EGFR_EGFR_1ina_integral_to_membrane or EGFR_EGFR_EGF_EGF_GRB2_GAB1_1ina_integral_to_membrane))) blue _h_2434_23 ((EGFR_EGFR_1act_integral_to_membrane_v1 or EGFR_EGFR_EGF_EGF_GRB2_GAB1_1act_integral_to_membrane_v1) and ( not (EGFR_EGFR_1ina_integral_to_membrane or EGFR_EGFR_EGF_EGF_GRB2_GAB1_1ina_integral_to_membrane))) blue _h_2434_20 ((EGFR_EGFR_1act_integral_to_membrane_v1 or EGFR_EGFR_EGF_EGF_GRB2_GAB1_1act_integral_to_membrane_v1) and ( not (EGFR_EGFR_1ina_integral_to_membrane or EGFR_EGFR_EGF_EGF_GRB2_GAB1_1ina_integral_to_membrane))) grey blue _h_2434_26 ((EGFR_EGFR_1act_integral_to_membrane_v1 or EGFR_EGFR_EGF_EGF_GRB2_GAB1_1act_integral_to_membrane_v1) and ( not (EGFR_EGFR_1ina_integral_to_membrane or EGFR_EGFR_EGF_EGF_GRB2_GAB1_1ina_integral_to_membrane))) blue _h_2434_27 ((EGFR_EGFR_1act_integral_to_membrane_v1 or EGFR_EGFR_EGF_EGF_GRB2_GAB1_1act_integral_to_membrane_v1) and ( not (EGFR_EGFR_1ina_integral_to_membrane or EGFR_EGFR_EGF_EGF_GRB2_GAB1_1ina_integral_to_membrane))) blue _h_2434_24 ((EGFR_EGFR_1act_integral_to_membrane_v1 or EGFR_EGFR_EGF_EGF_GRB2_GAB1_1act_integral_to_membrane_v1) and ( not (EGFR_EGFR_1ina_integral_to_membrane or EGFR_EGFR_EGF_EGF_GRB2_GAB1_1ina_integral_to_membrane))) blue _h_2434_25 ((EGFR_EGFR_1act_integral_to_membrane_v1 or EGFR_EGFR_EGF_EGF_GRB2_GAB1_1act_integral_to_membrane_v1) and ( not (EGFR_EGFR_1ina_integral_to_membrane or EGFR_EGFR_EGF_EGF_GRB2_GAB1_1ina_integral_to_membrane))) grey blue _h_2434_28 ((EGFR_EGFR_1act_integral_to_membrane_v1 or EGFR_EGFR_EGF_EGF_GRB2_GAB1_1act_integral_to_membrane_v1) and ( not (EGFR_EGFR_1ina_integral_to_membrane or EGFR_EGFR_EGF_EGF_GRB2_GAB1_1ina_integral_to_membrane))) grey grey grey _h_5063_3 blue RHOA_GTP_1act and ROCK2 _h_5063_1 blue CD44 and CDC42_GTP_1act red grey red grey grey red red red _h_6253 blue alpha7_beta1_Integrin red grey grey grey red red red grey blue _h_4597 Ran_GTP blue _h_267 PI_3_4_5_P3_plasma_membrane red red red red grey grey grey grey red red grey grey red _h_263 blue GRB2_SOS1_cytoplasm grey blue _h_260 PI_4_5_P2 or Phosphatidic_acid grey blue _h_2870 (JUN_FOS_TRIP6_1act_nucleus and ( not JUN_FOS_GR_TRIP6_cortisol_GR_alpha__dimer__1act_nucleus)) blue _h_1753 RAS_family_GTP_H_RAS_isoform_1_GTP_v1 or RAS_family_GTP_N_RAS_GTP_v1 red blue _h_3054 CDC42_GTP_1act_plasma_membrane or GCKR_1act or GCK_1act or GLK_1act or IFN_gamma_IFN_gammaR_JAK1_JAK1_JAK2_JAK2_1act or LAT_GRAP2_SLP76_HPK1_HIP_55_CRK_family_1act_integral_to_membrane_LAT_10O_GRAP2_HPK1_1O_Crk_HIP_55_2O_SLP76_3O or LAT_GRAP2_SLP76_HPK1_HIP_55_CRK_family_1act_integral_to_membrane_LAT_10O_GRAP2_HPK1_1O_HIP_55_2O_CRKL_SLP76_3O or MAP3K11_1O_1O_1act_plasma_membrane or MAP4K4_1act or NESK_1act or PAK2_1act or RAC1_GTP_1act_plasma_membrane or TNIK_1act or TRAIL_TRAILR1_FADD_TRADD_RIP_TRAF2_integral_to_membrane or TRAIL_TRAILR2_FADD_TRADD_RIP_TRAF2_integral_to_membrane or alphaV_beta3_Integrin_Osteopontin or ceramide grey grey blue _h_4520_3 Akt1_1O_1O_1act blue _h_4520_2 Akt1_1O_1O_1act blue _h_4520_1 Akt1_1O_1O_1act red red grey grey grey red red grey red grey grey blue _h_4598 ((CXCR4_1act_1O or Prolactin_Receptor_Prolactin) or Src_1act_1O) red red blue _h_5149 TAp63g__tetramer__1act_nucleus_v2 blue _h_5145 Crk_1act_cell_cell_junction _h_5144 blue HEY1_nucleus blue _h_5147 Src_1O grey _h_5141 blue WNT_inhibitory_factor_1_extracellular_region blue _h_5140 dNp63a__tetramer__nucleus_v1 red red red _h_6179 blue IRAK and IRAK2 and IRAK4 _h_6178 blue Calcineurin_A_alpha_beta_B1 _h_2930 blue ((FZD8_integral_to_membrane and LRP6_integral_to_membrane) and WNT1_extracellular_region) grey red grey red grey grey grey grey red red _h_4494 blue SMAD1_cytoplasm and SMAD7_SMURF1 _h_3846 blue BRCA1_BARD1 red red _h_5649 blue RANBP10 and RANBP9_SOS1_cytoplasm blue _h_3645 CBL_1O_1act_cytoplasm or IL23_IL23R_JAK2_TYK2_1act_integral_to_membrane or IL4_IL4R_JAK1_IL2R_gamma_JAK3_FES_IRS2_1act_integral_to_membrane or IL4_IL4R_JAK1_IL2R_gamma_JAK3_IRS1_1act_integral_to_membrane or IL4_IL4R_JAK1_IL2R_gamma_JAK3_SHP1_1act_integral_to_membrane red red blue _h_5858 Ephrin_B_EPHB1_1act_integral_to_membrane blue _h_4495 ERK5_1O_1O_1act_nucleus or Erk2_1O_1O_1act red red grey grey red red grey grey _h_6273 blue sTNF_alpha_TNFR1A_1act_integral_to_membrane blue _h_5640 IFN_gamma_IRF1 red blue _h_5641 p53__tetramer__nucleus_v2 red blue _h_4026_1 EGFR_EGFR_EGF_EGF_1act_endosome_v2 blue _h_2306 Ca2__cell_cell_junction or PI_4_5_P2_cell_cell_junction grey grey blue _h_2434_81 ((EGFR_EGFR_1act_integral_to_membrane_v1 or EGFR_EGFR_EGF_EGF_GRB2_GAB1_1act_integral_to_membrane_v1) and ( not (EGFR_EGFR_1ina_integral_to_membrane or EGFR_EGFR_EGF_EGF_GRB2_GAB1_1ina_integral_to_membrane))) blue _h_5673 SPPase1 grey grey grey blue _h_807_78 FASLG_FAS__trimer__Src_Syk_1act_integral_to_membrane or TRAIL__trimer__extracellular_region grey grey blue _h_807_72 FASLG_FAS__trimer__Src_Syk_1act_integral_to_membrane or TRAIL__trimer__extracellular_region blue _h_807_73 FASLG_FAS__trimer__Src_Syk_1act_integral_to_membrane or TRAIL__trimer__extracellular_region blue _h_807_70 FASLG_FAS__trimer__Src_Syk_1act_integral_to_membrane or TRAIL__trimer__extracellular_region blue _h_807_71 FASLG_FAS__trimer__Src_Syk_1act_integral_to_membrane or TRAIL__trimer__extracellular_region blue _h_807_76 FASLG_FAS__trimer__Src_Syk_1act_integral_to_membrane or TRAIL__trimer__extracellular_region blue _h_807_77 FASLG_FAS__trimer__Src_Syk_1act_integral_to_membrane or TRAIL__trimer__extracellular_region blue _h_807_74 FASLG_FAS__trimer__Src_Syk_1act_integral_to_membrane or TRAIL__trimer__extracellular_region blue _h_807_75 FASLG_FAS__trimer__Src_Syk_1act_integral_to_membrane or TRAIL__trimer__extracellular_region grey blue _h_4238 Ca2__cytoplasm or PLCgamma1_3O_1act_cytoplasm red red _h_4234 blue EPO_EPOR__dimer_ blue _h_4235 EGF_EGFR_1act or PKC_alpha_1act grey _h_1418 blue alphaIIb_beta3_Integrin_integral_to_membrane _h_4230 blue E2_ERA__dimer__1act_nucleus grey blue _h_4232 EGFR_EGFR_EGF_EGF_1act_integral_to_membrane_v1 _h_929 blue ARF_GAP1_v_SNARE_Golgi_to_ER_transport_vesicle_membrane and coatomer_protein_complex_ARF1_GTP_ARF_GAP1_Golgi_to_ER_transport_vesicle_membrane grey grey grey red red red grey red red red _h_2694 blue TIF2_nucleus _h_2695 blue alphav_beta1_Integrin_integral_to_membrane blue _h_3348_1 FAK_Src_Yes_Fyn_1act_focal_adhesion_v2_Fyn_1O_1act_FAK_6O_1act or FAK_Src_Yes_Fyn_1act_focal_adhesion_v2_Src_1act_1O_FAK_6O_1act _h_2690 blue VEGFR1_homodimer_plasma_membrane blue _h_2692 FOXM1B_nucleus red grey _h_1349 blue alpha5_beta1_Integrin_integral_to_membrane blue _h_1348 p53__tetramer__nucleus_v2 red grey red blue _h_1341 Erk1_1O_1act_1O_cytoplasm or Erk2_1O_1O_1act_cytoplasm _h_1340 blue Dynein_intermediate_chain and LIS1 and NudC _h_1347 blue IGF1_1act and PKC_delta and not ceramide _h_1346 blue EGFR_EGFR_EGF_EGF_1act_integral_to_membrane_v3 blue _h_1345 Fra1_JUNB_1act_nucleus _h_1344 blue NGF__dimer__p75_NTR__1act_integral_to_membrane _h_4493_4 blue TSC1_TSC2_14_3_3_family_1ina_TSC2_TSC1_YWHAQ _h_4493_5 blue REDD1 _h_4493_6 blue TSC1_TSC2_14_3_3_family_1ina_YWHAB_TSC2_TSC1 grey red _h_4493_2 blue REDD1 red grey red red grey _h_481 blue TLR4_MD2_integral_to_membrane grey grey grey grey red red grey red red _h_4509_1 blue NT3__dimer__TRKC_1act_integral_to_membrane and RAS_family_GTP_1act_plasma_membrane_H_RAS_isoform_1_GTP_v1 blue _h_486 JUN_ATF2_1act_nucleus red grey _h_5973 blue GPC1_plasma_membrane or NO grey blue _h_565 Myb_nucleus blue _h_564 N_WASP_1act _h_567 blue PLCgamma1_1act_cytoplasm grey _h_560 blue BMPR2__homodimer__integral_to_membrane and FKBP12_ALK2__dimer__1ina_integral_to_membrane blue _h_563 E_cadherin_Ca2__beta_catenin_alpha_catenin_p120_catenin_cell_cell_junction_v1 or nectin_2_dimer__I_afadin_I_afadin_nectin_2_dimer_I_afadin_I_afadin_cell_cell_junction red _h_1252 blue CRLK_C3G and (RELN_LRP8 or RELN_VLDLR) red grey red blue _h_5529 Myb_nucleus grey grey grey red red grey blue _h_2283_1 ROCK2_1act or ROCK_1act grey grey grey red grey red grey red blue _h_708 ((STAT5A_B__dimer__1act_nucleus or STAT5A__dimer__active_1act_nucleus_v2) or STAT5B__dimer__1act_nucleus) red _h_700 blue HDAC1_nucleus blue _h_703 p53__tetramer__nucleus_v2 blue _h_702 Fc_receptor_complex or aMb2_protein_ligands blue _h_705 MYC_Max_nucleus_v2 _h_704 blue DAB1 and (RELN_LRP8 or RELN_VLDLR) _h_707 blue CBL blue _h_706 dNp63a__tetramer__nucleus_v2 blue _h_3275 p53__tetramer__nucleus_v2 blue _h_3274 CREB1_nucleus or FOXA2_nucleus_v1 or FOXA2_nucleus_v2 blue _h_3277 uPA_uPAR_1act_plasma_membrane_v2 red blue _h_3271 IQGAP1_1act_cell_cortex or RHOA_GTP_1act_plasma_membrane blue _h_3270 Thrombin blue _h_1036_109 Arf6_GTP_1act or Arf6_GTP_1act_plasma_membrane blue _h_1036_108 Arf6_GTP_1act or Arf6_GTP_1act_plasma_membrane blue _h_1036_107 Arf6_GTP_1act or Arf6_GTP_1act_plasma_membrane grey blue _h_1036_105 Arf6_GTP_1act or Arf6_GTP_1act_plasma_membrane red blue _h_1036_103 Arf6_GTP_1act or Arf6_GTP_1act_plasma_membrane _h_3278 blue PRL_1 blue _h_1036_101 Arf6_GTP_1act or Arf6_GTP_1act_plasma_membrane blue _h_1036_100 Arf6_GTP_1act or Arf6_GTP_1act_plasma_membrane grey _h_1406_1 blue NCK1 _h_1406_2 blue HGF_dimer__MET_dimer__GAB1_N_WASP_1act_integral_to_membrane grey grey _h_305 blue Aurora_C and INCENP grey blue _h_3882 mTOR_1O_1act red grey blue _h_5899_24 ErbB2_ErbB3_neuregulin_1_beta_1act_integral_to_membrane_v1 blue _h_5899_25 ErbB2_ErbB3_neuregulin_1_beta_1act_integral_to_membrane_v1 grey red grey red blue _h_5899_22 ErbB2_ErbB3_neuregulin_1_beta_1act_integral_to_membrane_v1 red _h_942_2 blue (CDK4_6_Cyclin_D_CDK4_Cyclin_D1 or CDK4_6_Cyclin_D_CDK4_Cyclin_D2 or CDK4_6_Cyclin_D_CDK4_Cyclin_D3 or CDK4_6_Cyclin_D_CDK6_Cyclin_D1 or CDK4_6_Cyclin_D_CDK6_Cyclin_D2 or CDK4_6_Cyclin_D_CDK6_Cyclin_D3) and not (CDK4_6_Cyclin_D_p16INK4a_v1_CDK4_Cyclin_D2_p16INK4a or CDK4_6_Cyclin_D_p16INK4a_v1_CDK4_Cyclin_D3_p16INK4a or CDK4_6_Cyclin_D_p16INK4a_v1_CDK4_p16INK4a_Cyclin_D1 or CDK4_6_Cyclin_D_p16INK4a_v1_CDK6_Cyclin_D2_p16INK4a or CDK4_6_Cyclin_D_p16INK4a_v1_CDK6_Cyclin_D3_p16INK4a or CDK4_6_Cyclin_D_p16INK4a_v1_CDK6_p16INK4a_Cyclin_D1) blue _h_5899_28 ErbB2_ErbB3_neuregulin_1_beta_1act_integral_to_membrane_v1 blue _h_5899_29 ErbB2_ErbB3_neuregulin_1_beta_1act_integral_to_membrane_v1 red _h_942_3 blue (CDK4_6_Cyclin_D_CDK4_Cyclin_D1 or CDK4_6_Cyclin_D_CDK4_Cyclin_D2 or CDK4_6_Cyclin_D_CDK4_Cyclin_D3 or CDK4_6_Cyclin_D_CDK6_Cyclin_D1 or CDK4_6_Cyclin_D_CDK6_Cyclin_D2 or CDK4_6_Cyclin_D_CDK6_Cyclin_D3) and not (CDK4_6_Cyclin_D_p16INK4a_v1_CDK4_Cyclin_D2_p16INK4a or CDK4_6_Cyclin_D_p16INK4a_v1_CDK4_Cyclin_D3_p16INK4a or CDK4_6_Cyclin_D_p16INK4a_v1_CDK4_p16INK4a_Cyclin_D1 or CDK4_6_Cyclin_D_p16INK4a_v1_CDK6_Cyclin_D2_p16INK4a or CDK4_6_Cyclin_D_p16INK4a_v1_CDK6_Cyclin_D3_p16INK4a or CDK4_6_Cyclin_D_p16INK4a_v1_CDK6_p16INK4a_Cyclin_D1) grey grey blue _h_3318 E_cadherin_Ca2__beta_catenin_gamma_catenin_alpha_catenin_p120_catenin_cell_cell_junction_v2 grey _h_4076_1 blue (FOXO4_14_3_3_family_nucleus_YWHAQ_FOXO4_1O_2O and Ran_GTP_Exportin_1) _h_3312 blue Eps8 blue _h_3313 (((JUN_FOSNFAT1_c_4_1act_nucleus_c_Jun_2O_NFAT1_1O_7O_2s_1act_nucleus_FOS_1O_1O or JUN_FOSNFAT1_c_4_1act_nucleus_c_Jun_2O_NFAT4_1act_nucleus_FOS_1O_1O) or JUN_FOSNFAT1_c_4_1act_nucleus_c_Jun_2O_NFATc_1act_nucleus_FOS_1O_1O) and ( not ((NFAT1_c_4_PPARG_1ina_nucleus_NFAT1_1O_7O_2s_1act_nucleus_PPARG_nucleus or NFAT1_c_4_PPARG_1ina_nucleus_NFAT4_1act_nucleus_PPARG_nucleus) or NFAT1_c_4_PPARG_1ina_nucleus_NFATc_1act_nucleus_PPARG_nucleus))) blue _h_3310 ErbB2_ErbB3_neuregulin_1_beta_1act_integral_to_membrane_v1 blue _h_3311 Ephrin_A1_EPHA2_1act_integral_to_membrane blue _h_3316 JUN_ATF2_1act_nucleus _h_3317 blue BRCA2 and FANCD2 and FANCG_1O red red red blue _h_1667 STAT1__dimer__1act_v1 or STAT3__dimer___1act grey grey grey blue _h_66_1 Ran_GTP_Exportin_1 grey blue _h_1661 PDK1_Src_Hsp90_1act_plasma_membrane or PI_3_4_5_P3_plasma_membrane blue _h_5528 ATF2_2O_1act_nucleus blue _h_807_67 FASLG_FAS__trimer__Src_Syk_1act_integral_to_membrane or TRAIL__trimer__extracellular_region grey blue _h_2220 IL2_IL2R_1act_integral_to_membrane red blue _h_807_69 FASLG_FAS__trimer__Src_Syk_1act_integral_to_membrane or TRAIL__trimer__extracellular_region blue _h_6331 PLK1_1O_1act_kinetochore grey grey blue _h_1085 (AR_T_DHT_nucleus or supervillin) grey red blue _h_2223 Tie2_Ang1_ABIN2_1act grey grey grey grey blue _h_6089 CD40_CD40L__trimer__TRAF2__trimer__cIAP1_cIAP2_membrane_raft grey _h_4594_6 blue Erk2_1O_1O_1act grey grey _h_4594_5 blue Erk2_1O_1O_1act red blue _h_1083 LPA_LPA4 red grey blue _h_4591 Dynamin_GTP grey _h_4593 blue HDAC5_nucleus red _h_4595 blue gamma_catenin_1O_cytoplasm grey grey grey _h_4599 blue alpha4_beta1_Integrin_VCAM1_integral_to_membrane grey blue _h_4845 MYC_Max_nucleus_v2 red blue _h_4843 MYC_Max_TRRAP_TIP60_TIP49A_TIP49B_BAF53_nucleus grey _h_4841 blue CDK5 grey red red blue _h_380_1 BRAF_14_3_3_1act_plasma_membrane_14_3_3_E_BRAF_1O_2O or BRAF_14_3_3_1act_plasma_membrane_BRAF_1O_2O_YWHAS or BRAF_14_3_3_1act_plasma_membrane_BRAF_1O_2O_YWHAZ or BRAF_14_3_3_1act_plasma_membrane_YWHAB_BRAF_1O_2O or BRAF_14_3_3_1act_plasma_membrane_YWHAG_BRAF_1O_2O or BRAF_14_3_3_1act_plasma_membrane_YWHAQ_BRAF_1O_2O or RAF1_14_3_3_1act_plasma_membrane_RAF1_1O_3O_14_3_3_E or RAF1_14_3_3_1act_plasma_membrane_RAF1_1O_3O_YWHAB or RAF1_14_3_3_1act_plasma_membrane_RAF1_1O_3O_YWHAG or RAF1_14_3_3_1act_plasma_membrane_RAF1_1O_3O_YWHAQ or RAF1_14_3_3_1act_plasma_membrane_RAF1_1O_3O_YWHAS or RAF1_14_3_3_1act_plasma_membrane_RAF1_1O_3O_YWHAZ or RAF1_BRAF_14_3_3_14_3_3_1act_plasma_membrane_v1 grey grey grey red grey grey red grey grey grey grey red blue _h_3715 (CREB1_1act_nucleus or ELK1_SRF_1act_nucleus_v1) red red grey grey red red grey grey red blue _h_3501 JUN_FOS_1act_nucleus_v4 blue _h_2171 (RCH1__importin_beta and ( not NRON_rna)) blue _h_3868 p53__tetramer__nucleus_v2 red red blue _h_3507 CHK1 blue _h_3863 Aurora_B_chromatin _h_3864 blue E2_ERA__dimer__1act_nucleus grey blue _h_3866 SPHK1 or SPHK2 red _h_2193 blue PDGF_BB_PDGFRB__dimer__1act_integral_to_membrane_v1 blue _h_2192 HIF1A_ARNT_nucleus _h_2191 blue TFGBI blue _h_2190 (((JUN_FOSNFAT1_c_4_1act_nucleus_c_Jun_2O_NFAT1_1O_7O_2s_1act_nucleus_FOS_1O_1O or JUN_FOSNFAT1_c_4_1act_nucleus_c_Jun_2O_NFAT4_1act_nucleus_FOS_1O_1O) or JUN_FOSNFAT1_c_4_1act_nucleus_c_Jun_2O_NFATc_1act_nucleus_FOS_1O_1O) or PKC_theta_1act_plasma_membrane) blue _h_2197 CK1_gamma_1act_membrane_raft grey blue _h_4226 MYC_Max_P_TEFb_nucleus _h_2199 blue PIP5K1C_1act blue _h_2198 FURIN_intracellular red red grey grey grey grey grey grey grey grey grey blue _h_4221 E2F4_DP2_GCN5_nucleus grey blue _h_3710 not CO and (BMAL_CLOCK_NPAS2_nucleus or HEME or NADPH) red _h_175 blue CRK_II_cytoplasm and FAK1_cytoplasm and TRIP6_1O and paxillin_cytoplasm red red grey grey red blue _h_2196 (SMAD3_SMAD4_1act_nucleus and ( not SMAD3_SMAD4_GR_1act_nucleus)) grey blue _h_5088 TRPC6_1act grey blue _h_1644 (NF_kappa_B1_p50_RelA_I_kappa_B_alpha_1act_cytoplasm_v2 or STAT3__dimer___1act) grey blue _h_1642 Halofuginone grey blue _h_1640 RAP1_GTP_1act_endosome red _h_5080 blue BAF53_nucleus and MYC_Max_nucleus_v2 and TIP49A_TIP49B_nucleus grey grey blue _h_5084 CK1_alpha or CK1_epsilon _h_5085 blue CBL_b and CD40_CD40L__trimer__integral_to_membrane grey blue _h_5087 Akt1_1O_1O_1act_plasma_membrane or EGF_EGFR_dimer_SHC_GRB2_SOS1_1act_integral_to_membrane red grey grey _h_3131_1 blue FAK and netrin_1_DCC_UNC5C_1act_integral_to_membrane _h_3131_2 blue FAK and Yes_1act grey grey grey _h_3567_2 blue 9cRA and Cbp_p300_PCAF_nucleus_PCAF_p300 and RAR_alpha blue _h_3099 Myb_nucleus grey grey blue _h_2735 FOXA1_nucleus grey grey blue _h_2732 JNK2_1O_1O_1act or Jnk1_1O_1act_1O grey grey red red blue _h_2739 Erk2_1O_1O_1act or PDGF_BB_PDGFRB__dimer__1act_integral_to_membrane_v1 or PKR_1act red grey blue _h_5330 NudC_2O_outer_kinetochore_of_condensed_chromosome grey blue _h_5336 TC10_GTP_CIP4_1act_membrane_raft blue _h_5337 (E2_ERA_nucleus or FOXA1_nucleus) grey _h_5335 blue IKK_alpha_cytoplasm and IKK_beta_cytoplasm red grey grey blue _h_1422 Myosin_VI_cell_cell_junction blue _h_1423 (( not MYC_Max_MIZ_1_nucleus) and ((CREB1_nucleus or SP1_3_nucleus) or TBP_nucleus)) _h_1420 blue TRAF6 blue _h_1421 JUN_ATF2_1act_nucleus red _h_6347 blue ceramide _h_6344 blue GTP_v1 and (PAR1_PAR3_1act_integral_to_membrane or PAR1_active_1act_integral_to_membrane or PAR4_active_1act_integral_to_membrane) blue _h_6345 KSR_1act_plasma_membrane or RAS_family_GTP_1act_plasma_membrane_H_RAS_isoform_1_GTP_v1 or RAS_family_GTP_1act_plasma_membrane_N_RAS_GTP_v1 grey _h_6348 blue CDO_integral_to_membrane blue _h_1429 DAG_v2 red red grey red grey _h_5493 blue Neurofibromin_1act_cytoplasm or RasGAP_1act blue _h_3488 CD22_1act_4O or EPO_EPOR__dimer__JAK2 _h_3489 blue TCR_CD3_MHC_II_CD4_LCK_ZAP_70_1act_integral_to_membrane or TCR_CD3_MHC_I_CD8_LCK_ZAP_70_1act_integral_to_membrane grey grey blue _h_3482 PKA_1act _h_3483 blue HGF_extracellular_region grey _h_2688 blue ASK1 red _h_3487 blue HEY2_nucleus _h_6083 blue Syndecan_2 blue _h_3485 FBXO45 grey red grey blue _h_6361 PTP1B_plasma_membrane _h_5535 blue TRAF2 grey _h_6001_1 blue MKP1_1act blue _h_397 IL12_IL12R_TYK2_JAK2_1act_integral_to_membrane or IL23_IL23R_JAK2_TYK2_1act_integral_to_membrane or IL27_IL27R_JAK2_TYK2_1act or IL2_IL2R_1act_integral_to_membrane or Jak2_Leptin_Receptor_Leptin_1act or PI3K_1act_plasma_membrane_v1 or mTOR or p38_alpha_1O_1O_1act_v2 blue _h_2685 (JUN_JUN_FOS_1act_nucleus_v2_JUN or JUN_JUN_FOS_1act_nucleus_v2_JUN_FOS) grey grey red grey red blue _h_2683 PI_4_5_P2_cell_cell_junction blue _h_6082 ( not PP2A_Heterotrimer_1act) blue _h_6365 not crmA and (FASLG_FAS__trimer__FADD_FADD_1act_integral_to_membrane or TRAIL_TRAILR2_FADD_integral_to_membrane or sTNF_alpha_TNFR1A_TRADD_TRAF2_FADD_1act_endosome) red red red blue _h_6367 JUN_ATF2_1act_nucleus _h_3076_2 blue SP1 grey grey _h_1606 blue Cholesterol_v2 grey grey grey red red red red grey grey _h_1692_2 blue RBBP4 _h_1692_3 blue RB1_E2F1_3_DP_HDAC1_nucleus_HDAC1_DP1_E2F3_RB1 _h_5861_4 blue (FOXG1 and FOXO3A_1act_nucleus) _h_5861_5 blue FOXG1 and SMAD2_3_SMAD4_1act_nucleus_Smad3_2O_1act_SMAD4 _h_5861_6 blue FOXG1 and SMAD2_3_SMAD4_1act_nucleus_Smad3_2O_1act_SMAD4 grey grey _h_5861_1 blue (FOXG1 and FOXO1_1act_nucleus) grey _h_5861_3 blue (FOXG1 and FOXO4_1act_nucleus) _h_4060 blue alpha6_beta1_Integrin_integral_to_membrane _h_4063 blue Ephrin_A5_integral_to_membrane _h_4062 blue RAB5_GDP_1ina and RIN2_1act blue _h_4065 ATM_3O_1N_site_of_double_strand_break _h_959 blue MDM2 and TAp73b__tetramer__nucleus grey blue _h_4066 ((DAG_v2 or LAT_GRAP2_SLP76_VAV1_PI3K_Class_IA_1act) or TCR_CD3_MHC_I_CD8_LCK_ZAP_70_1act_integral_to_membrane) grey _h_4068 blue Ephrin_A1_EPHA2_1act_integral_to_membrane _h_956 blue alphav_beta3_Integrin red _h_950 blue CD40_CD40L__trimer__TRAF2__trimer__integral_to_membrane blue _h_951 VEGFR2_homodimer_VEGFA_homodimer_Src_1act_plasma_membrane blue _h_953 p38_alpha_1O_1O_1act_v2 or p38_beta_1O_1O_1act red _h_1336 blue FAK_1O_1O_1act_cytoplasm grey red blue _h_6207 Cannabinoid_receptor_1_1act_growth_cone red grey red blue _h_1604 TAp73b__tetramer__nucleus grey grey grey red blue _h_4518 PI3K_Class_IA_1act_plasma_membrane_v2 grey red red grey red grey red red grey red grey blue _h_4511 E2_ERA_nucleus grey red grey grey grey red grey red grey red red grey blue _h_4514 STAT6__dimer__1act_nucleus_v1 red red grey red red grey blue _h_4456 Cyclin_B1_CDK1_1act_v1 _h_4457 blue CaM_Ca2_ grey blue _h_4459 JUN_JUND_1act_nucleus blue _h_4516 DAG_v2 red grey _h_5647_3 blue E2F1_3_DP_DP1_E2F2 and RB1_nucleus _h_4069 blue E2_ERB__dimer__1act_nucleus red red blue _h_2506 PIN1 _h_5294 blue DOCK1 and RhoG_GTP_1act red blue _h_2321 TCR_CD3_MHC_II_CD4_Fyn_1act_integral_to_membrane_v2 and not SHP2 red grey blue _h_5297 FOXM1B_nucleus grey grey grey grey grey _h_1826_2 blue Gamma_Secretase_1act _h_1826_1 blue Gamma_Secretase_1act blue _h_3946 Erk2_1O_1O_1act _h_6206 blue PP1_C_PP_1G grey red grey _h_3944 blue Striatin grey grey grey blue _h_1724 CSE1L_nucleus or p53__tetramer__nucleus_v2 red blue _h_2097 Akt1_1O_1act_v1 _h_6500 blue CXCR4__dimer__integral_to_membrane grey grey _h_5829_3 blue LPA red blue _h_5130 Caspase_3_1act blue _h_5857 E2F3_DP_nucleus blue _h_5856 (MEKK1_2O_1act or MKK7) red blue _h_5854 Ca2__cytoplasm or PKC_delta_1act_plasma_membrane _h_5853 blue Cyclin_H and TFIIH grey _h_5851 blue LCOR blue _h_5850 MYC_Max_nucleus_v2 grey grey blue _h_2914 TCF4_beta_catenin_1act_nucleus grey blue _h_1727 GSK3A blue _h_1036_58 Arf6_GTP_1act or Arf6_GTP_1act_plasma_membrane grey red grey blue _h_1036_52 Arf6_GTP_1act or Arf6_GTP_1act_plasma_membrane blue _h_1036_53 Arf6_GTP_1act or Arf6_GTP_1act_plasma_membrane blue _h_1036_50 Arf6_GTP_1act or Arf6_GTP_1act_plasma_membrane blue _h_2019 GSK3beta_1ina_1O_cell_leading_edge blue _h_1036_56 Arf6_GTP_1act or Arf6_GTP_1act_plasma_membrane grey blue _h_1036_54 Arf6_GTP_1act or Arf6_GTP_1act_plasma_membrane grey blue _h_6085 MEKK2_1act _h_6084 blue APC_cytoplasm and beta_catenin_cytoplasm grey red grey red grey grey blue _h_6086 ((NFAT1_c_4__dimer__EGR1_NFAT1_1O_7O_2s_1act_nucleus_EGR1_nucleus or NFAT1_c_4__dimer__EGR1_NFAT4_1act_nucleus_EGR1_nucleus) or NFAT1_c_4__dimer__EGR1_NFATc_1act_nucleus_EGR1_nucleus) blue _h_3109 FOXA2_nucleus_v1 _h_3108 blue E_cadherin_Ca2__beta_catenin_alpha_catenin_p120_catenin_cell_cell_junction_v1 _h_3107 blue alpha8_beta1_Integrin_integral_to_membrane blue _h_3106 PI_4_5_P2_synaptic_vesicle_membrane _h_3105 blue 9cRA and DNA_rna and RXRs_LXRs_DNA blue _h_429_1 Exportin_1 red _h_3102 blue TPX2_microtubule blue _h_429_4 Exportin_1 blue _h_3100 mTORC1_1act red blue _h_5051_13 (RAS_family_GTP_1act_plasma_membrane_H_RAS_isoform_1_GTP_v1 or RAS_family_GTP_1act_plasma_membrane_N_RAS_GTP_v1) red blue _h_5051_12 (RAS_family_GTP_1act_plasma_membrane_H_RAS_isoform_1_GTP_v1 or RAS_family_GTP_1act_plasma_membrane_N_RAS_GTP_v1) grey red red grey red red grey red red grey grey grey red grey blue _h_2816 (JUNB_JUN_FOS_1act_nucleus_FOS_JUNB or JUNB_JUN_FOS_1act_nucleus_JUN_JUNB) red _h_124 blue alpha7X2_beta1_Integrin grey red grey grey grey blue _h_1723 Fer grey _h_587 blue Jagged_1_integral_to_membrane _h_2817 blue PI3K red grey grey red blue _h_122 CBP_nucleus or HDAC3_nucleus or TNF_alpha_TNFR1A or p300_nucleus grey grey grey grey grey grey red grey grey red _h_2038 blue p38_gamma_1O_1O_1act blue _h_2383 IL12_IL12R_TYK2_JAK2_1act_integral_to_membrane or IL12_IL12R_TYK2_JAK2_SPHK2_1act_integral_to_membrane or IL23_IL23R_JAK2_TYK2_1act_integral_to_membrane or IL27_IL27R_JAK2_TYK2_1act or RIP2 blue _h_1559 (TRAIL_TRAILR1_DAP3_GTP_FADD_integral_to_membrane or TRAIL_TRAILR2_FADD_integral_to_membrane or sTNF_alpha_TNFR1A_TRADD_TRAF2_FADD_1act_endosome) and not (Erk2_1O_1O_1act or c_FLIPS or sTNF_alpha_TNFR1A_TRADD_RIP_TRAF2_cIAP1_cIAP2_1act_integral_to_membrane) grey _h_578 blue G12_family_GTP_1act _h_2475 blue Sprouty2 grey grey blue _h_579 ErbB4_ErbB4_HBEGF_HBEGF_Prolactin_receptor_Prolactin_receptor_Prolactin_JAK2_1act_integral_to_membrane or IFN_gamma_1act_extracellular_region or IL12_IL12R_TYK2_JAK2_1act_integral_to_membrane or IL23_IL23R_JAK2_TYK2_1act_integral_to_membrane or IL27_IL27R_JAK2_TYK2_1act grey grey red blue _h_2508 (T_DHT_AR_TIF2_CARM1_nucleus and ( not T_DHT_AR_Cyclin_D3_CDK11_p58_nucleus)) _h_2509 blue LRPAP1 and SHH_Np_Cholesterol_extracellular_region red blue _h_2504 CDC42_GTP_1act or RAC1_GTP_1act_v1 or RHOA_GTP_1act blue _h_2505 ( not E2F3_DP_nucleus) grey _h_2507 blue GCS and UDP_D_glucose _h_2500 blue NT_4_5__dimer__p75_NTR__1act_integral_to_membrane blue _h_2501 CK2A1_1act_nucleus _h_2502 blue beta_catenin_1act_cytoplasm _h_2503 blue Laminin_11 grey grey _h_4214 blue p120_catenin_RhoA_GDP grey blue _h_2434_45 ((EGFR_EGFR_1act_integral_to_membrane_v1 or EGFR_EGFR_EGF_EGF_GRB2_GAB1_1act_integral_to_membrane_v1) and ( not (EGFR_EGFR_1ina_integral_to_membrane or EGFR_EGFR_EGF_EGF_GRB2_GAB1_1ina_integral_to_membrane))) grey _h_4210 blue Laminin_2 blue _h_807_57 FASLG_FAS__trimer__Src_Syk_1act_integral_to_membrane or TRAIL__trimer__extracellular_region blue _h_807_58 FASLG_FAS__trimer__Src_Syk_1act_integral_to_membrane or TRAIL__trimer__extracellular_region _h_572 blue VEGFA189__dimer__extracellular_region grey red blue _h_4219 TAp73b__tetramer__nucleus red red grey grey blue _h_1471 Erk2_1O_1O_1act or paxillin_1O_v1 or paxillin_1O_v2 _h_1047 blue alpha3_beta1_Integrin_integral_to_membrane _h_1984_2 blue FGFR4_FGF19 red grey grey red grey red _h_1470 blue EPOR_plasma_membrane and KIT and SCF_extracellular_region grey blue _h_5051_53 (RAS_family_GTP_1act_plasma_membrane_H_RAS_isoform_1_GTP_v1 or RAS_family_GTP_1act_plasma_membrane_N_RAS_GTP_v1) grey grey red grey grey blue _h_5622_1 Ephrin_A5_EPHA8_integral_to_membrane blue _h_5622_2 Ephrin_A5_EPHA8_integral_to_membrane grey red grey _h_542 blue VEGFR3_plasma_membrane _h_4994 blue JIP3 red grey red red red red grey red blue _h_973 dNp63a__tetramer__nucleus_v2 grey red grey _h_5331 blue DCC_integral_to_membrane and UNC5C_integral_to_membrane _h_971 blue VEGFR2__dimer__VEGFA__dimer__1act_integral_to_membrane_v1 blue _h_5228 p210_bcr_abl grey red red blue _h_4795 HIF1A_ARNT_nucleus grey blue _h_4042 IKK_beta_1act _h_4041 blue MED1 grey grey blue _h_4999 MYC_Max_TRRAP_TIP60_TIP49A_TIP49B_BAF53_nucleus _h_975 blue CRTC1 blue _h_22_2 PI_3_4_5_P3_cell_cell_junction blue _h_22_1 PI_3_4_5_P3_cell_cell_junction grey grey grey _h_1408 blue p210_bcr_abl _h_1360 blue Fibronectin_extracellular_matrix blue _h_1363 FOXO3A_nucleus grey blue _h_5743 TCF4_beta_catenin_1act_nucleus red grey _h_1369 blue SH2B_family and (BDNF__dimer__TRKB_1act_endosome_v2 or NGF__dimer__TRKA_1act_endosome or NT3__dimer__TRKC_1act_endosome or NT_4_5__dimer__TRKB_1act_endosome) _h_2633 blue (GTP_v1 and IL8_CXCR2_1act_integral_to_membrane_v1) _h_241 blue DAB1 and RELN_VLDLR red grey grey red grey blue _h_1036_121 Arf6_GTP_1act or Arf6_GTP_1act_plasma_membrane red blue _h_1036_123 Arf6_GTP_1act or Arf6_GTP_1act_plasma_membrane blue _h_1036_122 Arf6_GTP_1act or Arf6_GTP_1act_plasma_membrane blue _h_1036_125 Arf6_GTP_1act or Arf6_GTP_1act_plasma_membrane red blue _h_1036_127 Arf6_GTP_1act or Arf6_GTP_1act_plasma_membrane blue _h_1036_126 Arf6_GTP_1act or Arf6_GTP_1act_plasma_membrane blue _h_3297 NFAT1_1O_7O_2s_1act_nucleus or NFAT4_1act_nucleus or NFATc_1act_nucleus blue _h_3296 E2_ERA__dimer__1act_nucleus grey _h_3294 blue SAA1_extracellular_region and TLR2_integral_to_membrane _h_3293 blue PAFAH1B2 and PAFAH1B3 blue _h_3292 GNAI2_GTP_Hck_Fgr_Lyn_1act red blue _h_5629 Aurora_B _h_5624 blue VEGFC__dimer__extracellular_region and VEGFR2_integral_to_membrane and VEGFR3_integral_to_membrane blue _h_5625 TCF4_beta_catenin_TNIK_1act_nucleus blue _h_5626 B_cell_antigen_BCR_complex_LYN_v2 or Fyn_1O_1act or LYN_1act_1O or Lck_1O_1act or PI3K_1act_plasma_membrane_v2 or PI_3_4_P2_plasma_membrane or Src_1act_1O _h_5627 blue PDE6C_1act and RGS9_1_Gbeta5_R9AP _h_5621 blue VEGFR1_homodimer_NRP1_plasma_membrane _h_547 blue CABIN1_MEF2D_1ina_nucleus grey _h_545 blue GRB2 and p52_SHC grey red blue _h_541 BDNF__dimer__TRKB_1act_endosome_v2 or NGF__dimer__TRKA_1act_endosome or NT3__dimer__TRKC_1act_endosome or NT_4_5__dimer__TRKB_1act_endosome grey grey red grey red _h_6148 blue PLCgamma1_cytoplasm blue _h_548 PCAF_nucleus red grey grey grey red blue _h_5997 JUN_JUN_FOS_1act_nucleus_v1_FOS_JUN_2O_2O or JUN_JUN_FOS_1act_nucleus_v1_JUN_JUN_2O_2O or SP1_3_nucleus _h_5994 blue RAP1A_GTP_1act grey blue _h_5992 HLX1 or IL12_IL12R_TYK2_JAK2_1act_integral_to_membrane or IL18_IL18R_1act blue _h_5993 PRL_2_1S _h_5990 blue G12_GDP_1ina and GTP_v1 red grey grey _h_5998 blue ARF5_GDP_1ina and GRP1_1act_integral_to_membrane grey blue _h_67 Akt1_1O_1O_1act grey grey grey blue _h_4376 not CaM and (Erk2_1O_1O_1act or SCP1 or SCP2) grey _h_722 blue PML blue _h_721 IL2_IL2R_alpha_beta_gamma_JAK1_LCK_JAK3_SHC_GAB2_GRB2_SOS1_SHP2_PI3K_1act_integral_to_membrane blue _h_720 cortisol_GR_alpha__dimer__nucleus_v4 blue _h_727 TCF4_beta_catenin_TBLR1_TBL1_1act_nucleus_v1 red blue _h_2944_9 not E_cadherin_cytoplasm and (MAPK_14 or p120ctn) blue _h_2944_8 not E_cadherin_cytoplasm and (MAPK_14 or p120ctn) blue _h_2944_7 not E_cadherin_cytoplasm and (MAPK_14 or p120ctn) blue _h_2944_6 not E_cadherin_cytoplasm and (MAPK_14 or p120ctn) grey _h_728 blue IL8_extracellular_region blue _h_2944_3 not E_cadherin_cytoplasm and (MAPK_14 or p120ctn) blue _h_2944_2 not E_cadherin_cytoplasm and (MAPK_14 or p120ctn) blue _h_2944_1 not E_cadherin_cytoplasm and (MAPK_14 or p120ctn) _h_1611_2 blue (RAS_family_GDP_1ina_H_RAS_isoform_1_GDP_v1 and (((EGFR_EGFR_EGF_EGF_GRB2_SOS1_1act_endosome_v1 or EGFR_EGFR_EGF_EGF_p46_SHC_GRB2_SOS1_1act_endosome) or EGFR_EGFR_EGF_EGF_p52_SHC_GRB2_SOS1_1act_endosome_v1) or Ephrin_B_EPHB2_RasGAP_1act_integral_to_membrane)) _h_896 blue ADAM10_1act_integral_to_membrane grey grey _h_60 blue ((AP_2_adaptor_complex or Ezrin) or clathrin_heavy_chain_plasma_membrane) red blue _h_718 IL23_IL23R_JAK2_TYK2_1act_integral_to_membrane red grey grey red grey grey grey grey blue _h_383 (TAp63g__tetramer__1act_nucleus_v2 and ( not TAp63g__tetramer__p14ARF_1ina_nucleus)) blue _h_2144 CIN85_Endophilin_plasma_membrane or DMN1_GTP_1act or EPS15_1O_plasma_membrane or Epsin_1_plasma_membrane or SYNJ1 or amphiphysin_1act red red grey grey _h_2410 blue FGFR3_FGF_complex and Pyk2_RAFTK_cytoplasm blue _h_4869 PI3K_1act_plasma_membrane_v2 _h_4868 blue GIT1 and PAK1 blue _h_2147 E4F1_nucleus blue _h_5899_48 ErbB2_ErbB3_neuregulin_1_beta_1act_integral_to_membrane_v1 blue _h_5899_49 ErbB2_ErbB3_neuregulin_1_beta_1act_integral_to_membrane_v1 grey blue _h_5899_47 ErbB2_ErbB3_neuregulin_1_beta_1act_integral_to_membrane_v1 blue _h_4863 EPO_EPOR__dimer__JAK2 grey blue _h_5899_42 ErbB2_ErbB3_neuregulin_1_beta_1act_integral_to_membrane_v1 blue _h_5899_43 ErbB2_ErbB3_neuregulin_1_beta_1act_integral_to_membrane_v1 blue _h_5899_40 ErbB2_ErbB3_neuregulin_1_beta_1act_integral_to_membrane_v1 blue _h_5899_41 ErbB2_ErbB3_neuregulin_1_beta_1act_integral_to_membrane_v1 _h_5339 blue E2_ERA__dimer__1act_nucleus red blue _h_2142 (AR_T_DHT_nucleus and ( not p16INK4a)) grey grey grey blue _h_1858 CK1_alpha or CK2A1_nucleus or WNT1_LRP6_FZD1 grey red red red blue _h_2525 EOMES grey grey red blue _h_1294 IP3 grey _h_1852 blue Pellinos or UBC13_UEV1A grey red _h_4756_1 blue LYN blue _h_1850 Caspase_8_1act or Granzyme_B_cytoplasm red red red grey _h_1857 blue nectin_1_integral_to_membrane red _h_1856 blue Caspase_1__cleaved__1act and IL1_beta red red red blue _h_3940 HIF1A_ARNT_nucleus blue _h_1855 Perforin_1 red red _h_1145 blue MITF_nucleus blue _h_1854 MYC_Max_nucleus_v2 red red red grey red grey blue _h_1149 E2_ERA__dimer__PDI_1act_nucleus grey grey grey grey grey red _h_201_2 blue 14_3_3_E red grey grey _h_201_6 blue YWHAQ grey _h_201_4 blue YWHAZ _h_201_5 blue mTORC1_complex_1ina red grey grey grey grey grey red red grey red grey red red _h_1620 blue I_afadin_plasma_membrane grey grey _h_1623 blue Fra1_1O_2O_nucleus grey blue _h_1625 Myb_nucleus red blue _h_1995 MYC_Max_TRRAP_TIP60_TIP49A_TIP49B_BAF53_nucleus _h_1628 blue APC and PI_3_4_5_P3_plasma_membrane _h_1629 blue IKK_beta_cytoplasm and NEMO_1u_cytoplasm _h_1998 blue IL2R_alpha_integral_to_membrane and IL2R_beta_integral_to_membrane red red red red blue _h_3843 (( not (HDAC2_nucleus or p53__tetramer__nucleus_v7)) and ((((BRG1 or GCN5_L_ADA2B_TAF9_nucleus) or HZF_nucleus) or POU4F1_nucleus) or p53__tetramer__nucleus_v5)) red red _h_3847 blue HEY2_nucleus blue _h_3844 not FASLG_FAS__trimer__FADD_FADD_CASP8_CASP8_1act_integral_to_membrane_v1 blue _h_3845 FOXM1B_nucleus grey blue _h_3848 Myb_nucleus grey red grey blue _h_2711 TAp63a__tetramer__1act_nucleus_v3 red red _h_2712 blue hPC2_nucleus blue _h_2714 (MYOD_nucleus or RB1_nucleus) blue _h_2717 JUN_JUND_1act_nucleus red _h_2719 blue EGFR_integral_to_membrane grey blue _h_5051_7 (RAS_family_GTP_1act_plasma_membrane_H_RAS_isoform_1_GTP_v1 or RAS_family_GTP_1act_plasma_membrane_N_RAS_GTP_v1) grey red blue _h_5003 MYC_Max_nucleus_v2 _h_6478 blue RELN_VLDLR_DAB1 and not PP2 blue _h_5004 PDK1_1O_1act grey grey blue _h_4862 beta_catenin_nucleus grey blue _h_6501 PI_3_4_5_P3_plasma_membrane blue _h_1198 HIF1A_ARNT_nucleus red blue _h_5006 ARF1_GTP_ARHGAP10_1act_Golgi_to_ER_transport_vesicle_membrane grey blue _h_1193 MYC_Max_nucleus_v2 blue _h_1190 JNK2_1O_1O_1act or JNK2_1act_nucleus or JNK3_1act_nucleus or JNK_1act_nucleus or Jnk1_1O_1act_1O blue _h_1191 p70S6K_3O_4O blue _h_1197 MYC_Max_nucleus_v2 _h_1194 blue alphav_beta3_Integrin_integral_to_membrane _h_1195 blue CD40_CD40L__trimer__integral_to_membrane grey red blue _h_5056 CDC42_GTP_1act_plasma_membrane grey grey grey grey red _h_1545 blue uPA_1act_extracellular_region_v2 grey _h_1544 blue nectin_1_dimer__I_afadin_I_afadin_integral_to_membrane _h_1627 blue Dynactin_Complex_v2 and JIP4 _h_2003_1 blue Syndecan_4 blue _h_1546 SCF_KIT_1act grey blue _h_6261 TIP60_1act_site_of_double_strand_break grey red blue _h_6260 PLK1_1O_1act grey _h_6263 blue GRB2_SOS1_GAB_family_1act and IL6_IL6RA_gp130__dimer__JAK1_JAK1_LMO4_Hck_1act_integral_to_membrane grey red red grey grey blue _h_1934 (( not cortisol_GR_alpha__monomer__nucleus) and (Oct_1 or PBX1)) grey grey grey grey red blue _h_1036_95 Arf6_GTP_1act or Arf6_GTP_1act_plasma_membrane grey red _h_1937 blue GRAF red red _h_6268 blue SPOP grey red grey grey red grey _h_4901 blue SUMO1_cytoplasm and not Gam1 and (NPC_RanGAP1_SUMO1_RanBP2_Ubc9 or NPC_RanGAP1_SUMO1_Ubc9) blue _h_4009 PLD1_1act or PLD2_1act grey grey grey blue _h_4003 (BAD_4O_1act or BAX_1act) red blue _h_4001 CaM_Ca2__Calcineurin_A_alpha_beta_B1_1act_v2 red blue _h_4007 p300 and not SIRT1 red _h_4005 blue HDAC3_nucleus blue _h_1703 ((((((((((DHT_cytoplasm or EGFR_EGFR_EGF_EGF_1act_integral_to_membrane_v1) or GNB1_GNG2_1act_cytoplasm) or HGF_dimer__MET_dimer__1act_integral_to_membrane_v1) or HGF_dimer__MET_dimer__1act_integral_to_membrane_v3) or RALA_GTP_1act_plasma_membrane) or VEGFR2__dimer__VEGFA__dimer__1act_endosome) or VEGFR2__dimer__VEGFA__dimer__alphav_beta3_Integrin_Vitronectin_1act_integral_to_membrane) or alpha9_beta1_Integrin_Tenascin_C_integral_to_membrane_v2) or testosterone_cytoplasm) or uPA_uPAR_alphav_beta3_Integrin_Vitronectin_1act_integral_to_membrane) _h_1600_2 blue GUCA1A_1act blue _h_1521 ( not dNp63a__tetramer__nucleus_v2) blue _h_6502 PIP3_plasma_membrane grey red grey red blue _h_5899_46 ErbB2_ErbB3_neuregulin_1_beta_1act_integral_to_membrane_v1 grey _h_3617 blue Midkine red blue _h_4059_1 (((((((((((CD40_CD40L__trimer__TRAF2__trimer__integral_to_membrane or MKK4_1O_1O_1act) or MKK4_1act) or MKK7_1act) or RAC1_CDC42_GTP_1act) or RAC1_GTP_1act_v2) or RAL_GTP_1act) or ceramide) or p75_NTR__beta_APP_1act) or proBDNF__dimer__p75_NTR__Sortilin_TRAF6_NRIF_1act_integral_to_membrane) or proNGF__dimer__p75_NTR__Sortilin_NRAGE_1act_integral_to_membrane) or proNGF__dimer__p75_NTR__Sortilin_TRAF6_NRIF_1act_integral_to_membrane) grey grey grey red red _h_4436 blue EGFR_integral_to_membrane grey blue _h_4437 VEGFR2__dimer__VEGFA__dimer__1act_integral_to_membrane_v1 grey blue _h_1701 (( not JDP2_nucleus) and (ATF2_2O_1O_1act_nucleus or p300_nucleus)) red grey grey blue _h_3309 FOXA2_nucleus_v1 or HNF1A_HNF1B_nucleus or HNF1A__dimer__nucleus or HNF1B__dimer__nucleus grey red grey blue _h_390 CBP_nucleus or p300_nucleus _h_4184 blue Lecithin and Lecithin_Retinol_Acyl_Transferase red grey blue _h_4030 PKA_1act grey blue _h_4478 not SHIP and (Ca2__cytoplasm or DAG_v2) blue _h_4479 MIM_GLI1_1act_nucleus blue _h_2434_68 ((EGFR_EGFR_1act_integral_to_membrane_v1 or EGFR_EGFR_EGF_EGF_GRB2_GAB1_1act_integral_to_membrane_v1) and ( not (EGFR_EGFR_1ina_integral_to_membrane or EGFR_EGFR_EGF_EGF_GRB2_GAB1_1ina_integral_to_membrane))) blue _h_2434_69 ((EGFR_EGFR_1act_integral_to_membrane_v1 or EGFR_EGFR_EGF_EGF_GRB2_GAB1_1act_integral_to_membrane_v1) and ( not (EGFR_EGFR_1ina_integral_to_membrane or EGFR_EGFR_EGF_EGF_GRB2_GAB1_1ina_integral_to_membrane))) blue _h_2434_66 ((EGFR_EGFR_1act_integral_to_membrane_v1 or EGFR_EGFR_EGF_EGF_GRB2_GAB1_1act_integral_to_membrane_v1) and ( not (EGFR_EGFR_1ina_integral_to_membrane or EGFR_EGFR_EGF_EGF_GRB2_GAB1_1ina_integral_to_membrane))) blue _h_2434_67 ((EGFR_EGFR_1act_integral_to_membrane_v1 or EGFR_EGFR_EGF_EGF_GRB2_GAB1_1act_integral_to_membrane_v1) and ( not (EGFR_EGFR_1ina_integral_to_membrane or EGFR_EGFR_EGF_EGF_GRB2_GAB1_1ina_integral_to_membrane))) _h_4470 blue PKC_theta_1act_plasma_membrane blue _h_2434_65 ((EGFR_EGFR_1act_integral_to_membrane_v1 or EGFR_EGFR_EGF_EGF_GRB2_GAB1_1act_integral_to_membrane_v1) and ( not (EGFR_EGFR_1ina_integral_to_membrane or EGFR_EGFR_EGF_EGF_GRB2_GAB1_1ina_integral_to_membrane))) blue _h_2434_62 ((EGFR_EGFR_1act_integral_to_membrane_v1 or EGFR_EGFR_EGF_EGF_GRB2_GAB1_1act_integral_to_membrane_v1) and ( not (EGFR_EGFR_1ina_integral_to_membrane or EGFR_EGFR_EGF_EGF_GRB2_GAB1_1ina_integral_to_membrane))) blue _h_3307 PKC_beta_1act_plasma_membrane or PKC_delta_1act_plasma_membrane or PKC_epsilon_1act_plasma_membrane or PKC_isoenzymes_1act_plasma_membrane or PKC_theta_1act_plasma_membrane or PRKCG_1act_plasma_membrane or PRKCH_1act_plasma_membrane grey blue _h_2434_61 ((EGFR_EGFR_1act_integral_to_membrane_v1 or EGFR_EGFR_EGF_EGF_GRB2_GAB1_1act_integral_to_membrane_v1) and ( not (EGFR_EGFR_1ina_integral_to_membrane or EGFR_EGFR_EGF_EGF_GRB2_GAB1_1ina_integral_to_membrane))) grey red grey grey grey grey blue _h_507 STRAP_PRMT5_nucleus _h_4883 blue SKP2 _h_2894_12 blue 14_3_3_E_nucleus red red red red red grey grey blue _h_2434_21 ((EGFR_EGFR_1act_integral_to_membrane_v1 or EGFR_EGFR_EGF_EGF_GRB2_GAB1_1act_integral_to_membrane_v1) and ( not (EGFR_EGFR_1ina_integral_to_membrane or EGFR_EGFR_EGF_EGF_GRB2_GAB1_1ina_integral_to_membrane))) red _h_3989_1 blue sTNF_alpha_TNFR1A_TRADD_RIP_TRAF2_TAK1_TAB_family_1act_integral_to_membrane_TNFR1A_TRADD_TRAF2_1u_RIP_1u_TAB2_TAK1_1act_sTNF_alpha grey red _h_6216_2 blue TAB2 and TRAF6_1u_1act and not (p38_alpha_1O_1O_1act_v2 or p38_beta_1O_1O_1act) grey blue _h_807_31 FASLG_FAS__trimer__Src_Syk_1act_integral_to_membrane or TRAIL__trimer__extracellular_region grey grey grey blue _h_5871 MYC_Max_nucleus_v2 blue _h_5870 FOXM1C_2O_1act_nucleus _h_5873 blue LRP6 blue _h_5872 RBPJ_NICD_1act_nucleus _h_5875 blue beta_catenin_nucleus grey blue _h_5877 p38_delta_1O_1act_1O or p38_gamma_1O_1O_1act blue _h_5876 Jnk1_1O_1act_1O _h_5878 blue beta_catenin_nucleus red grey _h_2228 blue TRAIL__trimer__extracellular_region red blue _h_2434_29 ((EGFR_EGFR_1act_integral_to_membrane_v1 or EGFR_EGFR_EGF_EGF_GRB2_GAB1_1act_integral_to_membrane_v1) and ( not (EGFR_EGFR_1ina_integral_to_membrane or EGFR_EGFR_EGF_EGF_GRB2_GAB1_1ina_integral_to_membrane))) grey blue _h_1036_79 Arf6_GTP_1act or Arf6_GTP_1act_plasma_membrane blue _h_1036_74 Arf6_GTP_1act or Arf6_GTP_1act_plasma_membrane blue _h_1036_75 Arf6_GTP_1act or Arf6_GTP_1act_plasma_membrane blue _h_1036_76 Arf6_GTP_1act or Arf6_GTP_1act_plasma_membrane blue _h_1036_77 Arf6_GTP_1act or Arf6_GTP_1act_plasma_membrane grey blue _h_1036_71 Arf6_GTP_1act or Arf6_GTP_1act_plasma_membrane blue _h_1036_72 Arf6_GTP_1act or Arf6_GTP_1act_plasma_membrane blue _h_1036_73 Arf6_GTP_1act or Arf6_GTP_1act_plasma_membrane red grey red blue _h_1358 CSK_PAG1_1act or SDF1_CXCR4_CD45_1act_membrane_raft blue _h_3129 STAT1__dimer__1act_nucleus_v3 _h_5063_2 blue CD44 and ROCK2 grey grey grey grey _h_3125 blue STAT4__dimer__1act_nucleus_v2 _h_3124 blue NO and PGK _h_3127 blue RANTES red _h_2767 blue 3BP2 _h_5514 blue Rab_GGTase_beta_Rab_GGTase_alpha_1act red grey red grey red grey grey red red red red grey grey grey grey grey blue _h_2345 LPA_LPA1_2_3_LPA1_plasma_membrane_LPA or LPA_LPA1_2_3_LPA2_plasma_membrane_LPA or LPA_LPA1_2_3_LPA3_plasma_membrane_LPA or PKC_delta_1act_plasma_membrane red grey grey blue _h_4197 (E2_ERA__dimer__AIB1_1act_nucleus or IKKs) red red grey grey grey grey red grey grey _h_3263_42 blue FGFR1b_FGF3_1act grey grey red red grey red grey blue _h_2526 Antigen_IgE_Fc_epsilon_R1_LYN_SYK_v2 or EPO_EPOR__dimer__JAK2 or PDGF_PDGFRA_1act or SCF_KIT_1act red blue _h_2524 not ASIP and (AS160_CaM_Ca2_ or PKC_iota_1act_membrane_raft or PKC_zeta_1act_membrane_raft or SNARE_Synip_Golgi_to_ER_transport_vesicle_membrane or TC10_GTP_CIP4_Exocyst_1act_membrane_raft) red grey _h_2521 blue CHP1 and Calcineurin_A_alpha_beta_B1 grey grey red grey blue _h_2528 TAp73a__tetramer__1act_nucleus _h_2529 blue PTCH2_integral_to_membrane grey grey grey grey grey grey grey _h_4270 blue SMAD4_cytoplasm grey red blue _h_4273 alpha1_beta1_Integrin_TCPTP_p45_integral_to_membrane blue _h_4274 E2F1_3_DP_nucleus_DP1_E2F1 or E2F1_3_DP_nucleus_DP1_E2F2 or E2F1_3_DP_nucleus_DP1_E2F3 grey red grey _h_4278 blue NFAT1 _h_4279 blue JUN_2O_2O_nucleus blue _h_2724 NF_kappa_B1_p50_RelA_1act_nucleus blue _h_807_39 FASLG_FAS__trimer__Src_Syk_1act_integral_to_membrane or TRAIL__trimer__extracellular_region grey grey red red grey red red grey red grey blue _h_4776 PI3K_1act_plasma_membrane_v2 or SMO_1act_integral_to_membrane grey grey grey _h_2222 blue IGF_1R_heterotetramer_IGF1_GRB2_Sos_Shc grey grey grey grey grey red red grey grey red grey red red grey _h_1368 blue GTP_v1 grey _h_459 blue HPV_16_E6_E6AP red red grey grey blue _h_2637_7 ((GNB1_GNG2_1act_cytoplasm or PDGF_BB_PDGFRB__dimer__1act_integral_to_membrane_v1) or SDF1_CXCR4_JAK2_1act_integral_to_membrane) blue _h_2637_4 GNB1_GNG2_1act_cytoplasm or PDGF_BB_PDGFRB__dimer__1act_integral_to_membrane_v1 or SDF1_CXCR4_JAK2_1act_integral_to_membrane blue _h_2637_5 GNB1_GNG2_1act_cytoplasm or PDGF_BB_PDGFRB__dimer__1act_integral_to_membrane_v1 or SDF1_CXCR4_JAK2_1act_integral_to_membrane _h_5273 blue beta_APP blue _h_2637_3 GNB1_GNG2_1act_cytoplasm or PDGF_BB_PDGFRB__dimer__1act_integral_to_membrane_v1 or SDF1_CXCR4_JAK2_1act_integral_to_membrane red blue _h_2637_1 GNB1_GNG2_1act_cytoplasm or PDGF_BB_PDGFRB__dimer__1act_integral_to_membrane_v1 or SDF1_CXCR4_JAK2_1act_integral_to_membrane red _h_3730 blue GIPC_plasma_membrane and NGF__dimer__TRKA_1act_integral_to_membrane and (DNM1 or Dynein_Light_chain) grey _h_5279 blue GTP_v1 red _h_6067 blue FGFR_FGF_Syndecan_2_FRS2_1act and GRB2_cytoplasm and SHP2_cytoplasm red blue _h_6065 not E2F6_DP_nucleus grey grey grey _h_3263_44 blue FGFR1b_FGF10_1act grey grey blue _h_1457 NFAT1_1O_4O_2s_1act_nucleus _h_457 blue alpha_catenin_cytoplasm and p120_catenin_cytoplasm and (Fyn_1act_1O_plasma_membrane or Src_1O_1act_plasma_membrane) grey grey grey red grey red blue _h_451 HMGB1_TLR2_TLR1_MYD88_TIRAP_IRAK_IRAK2_IRAK4_1act_integral_to_membrane or HMGB1_TLR4_MD2__dimer__MYD88_TIRAP_IRAK_IRAK2_IRAK4_1act_integral_to_membrane or TLR2_TLR6_1act_integral_to_membrane red grey grey _h_981 blue E2_ER_alpha__dimer__PELP1_Src_1act_caveola_v1 _h_3729 blue BAX_nucleus blue _h_3728 p53__tetramer__nucleus_v2 red grey grey _h_3723 blue alphav_beta3_Integrin_integral_to_membrane _h_3722 blue CLDN1 and nectin_3_dimer__I_afadin_I_afadin_nectin_3_dimer__I_afadin_I_afadin_cell_cell_junction blue _h_3721 E2F1_DP_nucleus_v4 blue _h_3720 Myb_nucleus red grey red blue _h_2644 ARF6_GDP_1ina grey grey grey red red grey grey _h_1455 blue NRG1_extracellular_region _h_1389 blue alpha7X1_beta1D_Integrin blue _h_1388 Src_1act_1O blue _h_1387 STAT5A_B__dimer__1act_nucleus or STAT5A__dimer__active_1act_nucleus_v2 or STAT5B__dimer__1act_nucleus blue _h_1386 VEGFR2__dimer__VEGFA__dimer__1act_integral_to_membrane_v1 blue _h_1385 CBP_nucleus or p300_nucleus red blue _h_1382 ITCH_1act or LRIG1 or WWP1 blue _h_1381 (G9A or T_DHT_AR_TIF2_CARM1_nucleus) _h_1380 blue IL8_CXCR2_1act_integral_to_membrane_v1 grey blue _h_4191 not CaM_Ca2_ and (PKC_beta or PKC_epsilon or PKC_isoenzymes or PKC_zeta) red red red red red red grey grey grey _h_5606 blue Antigen_IgE_Fc_epsilon_R1 and GADs and GRB2 and PLCgamma1 and SLP76 blue _h_5607 EGFR_EGFR_EGF_EGF_integral_to_membrane_v1 blue _h_5602 MYC_Max_nucleus_v2 blue _h_5603 ( not cortisol_GR_alpha__monomer__nucleus) _h_5600 blue Akt1_1O_1O_1act_plasma_membrane and Hsp90_cytoplasm and mTOR_1O_1act and p70S6K_1act_1p red grey grey grey blue _h_5608 ((E2F4_DP2_nucleus or SP1) and ( not (E2F4_DP2_p107_p130_nucleus_DP2_E2F4_p130 or E2F4_DP2_p107_p130_nucleus_DP2_p107_E2F4))) red red grey red grey grey red _h_3263_48 blue FGFR1b_FGF3_1act grey blue _h_521 (((CEBPA or CEBPB) or CEBPD) or RB1_nucleus) blue _h_1453 MEF2C_1act_nucleus _h_523 blue FKBP38 grey blue _h_525 (AR_T_DHT_nucleus or Vav3) _h_524 blue PAI_1 _h_527 blue Tie2_Ang1_1act blue _h_526 Aurora_A blue _h_529 Akt1_1O_1O_1act_plasma_membrane grey grey grey _h_4011_6 blue FGFR1c_FGF1_plasma_membrane _h_4011_7 blue FGFR1c_FGF4_plasma_membrane _h_4011_4 blue Sef _h_4011_5 blue Sef grey grey _h_4011_1 blue Sef blue _h_5131_2 BRAF_1act_plasma_membrane or RAF1_1O_1act_v1 or RAF1_1O_1act_v2 or RAF1_1act or RAF1_2O_1act or netrin_1_DCC_1act_integral_to_membrane grey grey red _h_1652 blue Protein_4_1 grey grey _h_4011_9 blue Sef red _h_4498 blue PDGF_BB_PDGFRB__dimer__1act_integral_to_membrane_v1 red blue _h_852 (AR_T_DHT_nucleus or JHDM2A) grey _h_1426_2 blue Akt1_1O_1O_1act_plasma_membrane and MSP and YWHAB grey red red _h_1426_6 blue Akt1_1O_1O_1act_plasma_membrane and Ron and YWHAQ _h_1426_5 blue Akt1_1O_1O_1act_plasma_membrane and MSP and Ron _h_1426_4 blue Akt1_1O_1O_1act_plasma_membrane and MSP and Ron grey _h_2898 blue FOS_3O_2O_nucleus grey _h_2896 blue Arrestin grey _h_856 blue Bone_sialoprotein_2 _h_2892 blue CaM blue _h_2893 (JUN_FOS_NFAT1_c_4_1act_nucleus and ( not STAT4__dimer__1act_nucleus_v2)) grey red _h_2175_3 blue 9cRA and AIB1 and Rar_gamma1 blue _h_299 9cRA blue _h_298 cIAP2_cytoplasm blue _h_4233_2 Ephrin_B1_EPHB1_2_1act_integral_to_membrane_v1 _h_2175_2 blue 9cRA and AIB1 and Cbp_p300_PCAF_nucleus_PCAF_p300 red _h_292 blue WIP blue _h_291 (((((Centraspindlin_spindle_midzone_v1 or S1P1_S1P_1act_v1) or S1P_S1P3_Gi) or S1P_S1P5_Gi_v1) or aMb2_protein_ligands) or alphaM_beta2_Integrin) _h_297 blue NPC_RanGAP1_SUMO1_RanBP2_Ubc9 and SUMO1_nucleus red _h_295 blue Erk2_1O_1O_1act and IL2_IL2R_alpha_beta_gamma_JAK1_LCK_JAK3_SHC_GRB2_SOS1_GAB2_1act_integral_to_membrane blue _h_294 p53__tetramer__nucleus_v2 grey red blue _h_4358 Phosphatidic_acid_plasma_membrane_v1 grey red blue _h_4233_3 Ephrin_B1_EPHB1_2_1act_integral_to_membrane_v1 red grey grey _h_3434 blue P72 grey red _h_5964_2 blue E2F4_cytoplasm and p130 red _h_4802 blue ET2_extracellular_region blue _h_4801 ((AR_T_DHT_nucleus or SRG3) or Src_1) red _h_4807 blue GRB2 and RET9_GFRalpha1_GDNF_FRS2_membrane_raft _h_4804 blue Antigen_IgE_Fc_epsilon_R1_Fyn and PI3K_1act_plasma_membrane_v2 and SHP2 blue _h_4353 PKC_isoenzymes red blue _h_4351 ErbB2_ErbB3_neuregulin_1_beta_1act_integral_to_membrane_v1 red blue _h_3801 Erk2_1O_1O_1act_cytoplasm blue _h_5899_61 ErbB2_ErbB3_neuregulin_1_beta_1act_integral_to_membrane_v1 blue _h_5899_62 ErbB2_ErbB3_neuregulin_1_beta_1act_integral_to_membrane_v1 blue _h_5899_63 ErbB2_ErbB3_neuregulin_1_beta_1act_integral_to_membrane_v1 grey _h_6381_1 blue ((((AP2B2 and Caveolin_1) and PML_SARA_SMAD2_3_early_endosome) and TGFB_TGFBR2_TGFBR1_1act_integral_to_membrane) and ( not FKBP12)) blue _h_5899_66 ErbB2_ErbB3_neuregulin_1_beta_1act_integral_to_membrane_v1 _h_6381_3 blue ((((Caveolin_1 and PML_SARA_SMAD2_3_early_endosome) and SMAD7_SMURF1_2_nucleus_Smad7_SMURF1) and TGFB_TGFBR2_TGFBR1_1act_integral_to_membrane) and ( not FKBP12)) grey red grey red red red grey red grey red blue _h_2429 HGS_endosome or LST2_endosome or RAB5_GTP_1act_v2 or TSG101 or Vps24 grey grey grey red grey grey red _h_4960 blue LRP1 grey red blue _h_4411 (IHH_N_PTCH1_integral_to_membrane and ( not GLI3R_1ina)) red grey red grey grey red red red blue _h_4604 (NF_kappa_B1_p50_RelA and ( not cortisol_GR_alpha__monomer__nucleus)) red grey grey grey blue _h_1036_8 Arf6_GTP_1act or Arf6_GTP_1act_plasma_membrane blue _h_1036_9 Arf6_GTP_1act or Arf6_GTP_1act_plasma_membrane blue _h_3929 (( not Arfaptin_2_cytosol) and ((ARF1_GTP_1act_plasma_membrane or Antigen_IgE_Fc_epsilon_R1_Fyn) or PI_4_5_P2_plasma_membrane)) grey blue _h_1036_5 Arf6_GTP_1act or Arf6_GTP_1act_plasma_membrane blue _h_1036_6 Arf6_GTP_1act or Arf6_GTP_1act_plasma_membrane _h_1029 blue DLG1_cell_leading_edge blue _h_1036_1 Arf6_GTP_1act or Arf6_GTP_1act_plasma_membrane blue _h_1036_2 Arf6_GTP_1act or Arf6_GTP_1act_plasma_membrane grey blue _h_1817 Akt1_1O_1act_plasma_membrane_v2 grey grey red _h_1812 blue IL27RA_JAK1 and IL27_EBI3 blue _h_1811 MYC_Max_nucleus_v2 blue _h_2000 FOXO4_nucleus _h_28 blue Ca2__growth_cone red grey grey blue _h_2002 Cytochrome_C_cytoplasm or Mammalian_IAPs_DIABLO_1ina_DIABLO_XIAP or Mammalian_IAPs_DIABLO_1ina_cIAP1_DIABLO or Mammalian_IAPs_DIABLO_1ina_cIAP2_DIABLO grey blue _h_1264 p53__tetramer__nucleus_v2 grey red grey grey grey grey red red grey _h_1646 blue FRS2_family_active_1act and (BDNF__dimer__TRKB_1act_endosome_v2 or NGF__dimer__TRKA_1act_endosome or NT3__dimer__TRKC_1act_endosome or NT_4_5__dimer__TRKB_1act_endosome) grey _h_5044 blue HGF_dimer__MET_dimer__GAB1_1act_integral_to_membrane_v4 blue _h_5045 IRSP53_plasma_membrane or PI_3_4_5_P3_plasma_membrane or RAC1_GTP_1act_plasma_membrane grey blue _h_5047 SMURF1_nucleus blue _h_3994_3 GNB1_GNG2_1act_cytoplasm blue _h_5041 LEF1_beta_catenin_1act_nucleus_v1 blue _h_3994_1 GNB1_GNG2_1act_cytoplasm blue _h_5043 Fyn or Hck or LYN or Lck or Src or Yes blue _h_1608 Myb_nucleus grey blue _h_1978 ATF2_2O_1act_nucleus red grey grey _h_1974 blue PDE6A_B_1act or PDE6G_GNAT1_GTP_1act blue _h_1975 MAP4K4_4O_1act _h_1976 blue MKLP2_microtubule _h_1601 blue EGF_extracellular_region _h_1970 blue SHP2 _h_1971 blue alphaM_beta2_Integrin blue _h_1972 TACE blue _h_1973 Tie2_Ang1_1act_caveola grey red red grey grey grey grey grey blue _h_4848 (( not RhoA_1act) and (((((((Fibronectin_v1 or PI3K_1act_plasma_membrane_v2) or PI3K_1act_v2) or PKC_alpha_1act) or S1P1_S1P_1act_v1) or S1P_S1P3_Gi) or Syndecan_4) or alpha5_beta1_Integrin)) blue _h_2779 p53__tetramer__nucleus_v2 _h_2778 blue NCK2_cytoplasm grey grey blue _h_2773 GAB2_PI3K_SHP2_1act _h_2772 blue TRAF2_cytoplasm _h_2771 blue E_cadherin_gamma_catenin_basolateral_plasma_membrane grey red red blue _h_2775 not AS160 and (AS160_14_3_3_v2_14_3_3_E_AS160_2O_3O or AS160_14_3_3_v2_AS160_2O_3O_YWHAQ or AS160_14_3_3_v2_AS160_2O_3O_YWHAS or AS160_14_3_3_v2_AS160_2O_3O_YWHAZ or AS160_14_3_3_v2_YWHAB_AS160_2O_3O or AS160_14_3_3_v2_YWHAG_AS160_2O_3O) red red _h_6387 blue GRAP2_SLP76_1act_integral_to_membrane blue _h_456_2 Lethal_Factor_cytoplasm grey _h_6382 blue SAP30_nucleus and YY1_nucleus red blue _h_6380 PLK1_1O_1act or RHOA_GTP_1act blue _h_5744_3 CaM_Ca2__Calcineurin_A_alpha_beta_B1_1act_v1 grey blue _h_6389 (AR_T_DHT_nucleus and ( not SCP1)) grey red blue _h_2422 (FASLG_FAS__trimer__1act_integral_to_membrane or MEKK1_2O_1act) red grey blue _h_1208 STAT3__dimer__FOXO1_1act_nucleus and not GRB2_SOS1_GAB_family_SHP2_1act red red red _h_3778 blue GNB1_GNG2_1act blue _h_5417 CDK2_Cyclin_E1_nucleus _h_3263_81 blue FGFR1c_FGF4_1act _h_3263_80 blue FGFR1c_FGF6_1act blue _h_855 MEKK1_2O_1act _h_1215_2 blue (RAS_family_GDP_1ina_H_RAS_isoform_1_GDP_v1 and ((PDGF_BB_PDGFRB__dimer__GRB2_SOS1_SHP2_1act_integral_to_membrane or PDGF_BB_PDGFRB__dimer__p52_SHC_GRB2_SOS1_1act_integral_to_membrane) or SOS1_1act_plasma_membrane)) _h_1215_1 blue GTP_v1 and (PDGF_BB_PDGFRB__dimer__GRB2_SOS1_SHP2_1act_integral_to_membrane or PDGF_BB_PDGFRB__dimer__p52_SHC_GRB2_SOS1_1act_integral_to_membrane or SOS1_1act_plasma_membrane) grey red blue _h_2421 FOXA1_nucleus grey grey grey blue _h_1202 BRCA1_BARD1 grey red blue _h_1203 ( not dNp63g__tetramer__nucleus) red _h_254_4 blue PKC_alpha_1act and alpha6_beta4_Integrin_Laminin_hemidesmosome blue _h_1201 MYC_Max_nucleus_v2 red grey blue _h_5587 MYC_Max_nucleus_v2 blue _h_4399 PLK3 _h_254_6 blue PKC_alpha_1act and alpha6_beta4_Integrin_Laminin_hemidesmosome red _h_1108_2 blue Axin1_APC_GSK3_beta_catenin_cytoplasm_v1 blue _h_4392 (AR_T_DHT_nucleus or JUN_nucleus) blue _h_4391 (Erk2_1O_1O_1act and ( not SNAI1)) red blue _h_4397 VEGFR2__dimer__VEGFA__dimer__Src_1act_integral_to_membrane_v1 blue _h_4396 (E2_ERA__dimer__1act_nucleus and ( not ERA_SMAD4_nucleus)) blue _h_4395 SMYD2 and not p53__tetramer__nucleus_v4 blue _h_4394 (STAT3__dimer___1act and ( not Jak2_Leptin_Receptor_1ina)) red grey red grey red _h_4844 blue PRL_1 red red _h_1650_2 blue p38_alpha_1O_1O_1act_v2 red blue _h_5051_25 (RAS_family_GTP_1act_plasma_membrane_H_RAS_isoform_1_GTP_v1 or RAS_family_GTP_1act_plasma_membrane_N_RAS_GTP_v1) red grey grey red red _h_2170_2 blue Crk blue _h_3879 MYC_Max_nucleus_v2 _h_812 blue HDAC2_nucleus _h_2170_1 blue CRKL _h_4025 blue alpha4_beta1_Integrin_trailing_edge blue _h_4027 JUN_ATF2_1act_nucleus _h_1342 blue MPG and p300_nucleus _h_4020 blue RET51_GFRalpha1_GDNF_v1 _h_4023 blue SDF1_CXCR4_1act_integral_to_membrane blue _h_4022 ATR or RPA_ATR_ATRIP_RAD17_RFC2_5_9_1_1_TopBP1_1act_nucleus grey grey blue _h_4028 SHP2_1act_plasma_membrane grey grey grey grey blue _h_1267 Calpain_1 blue _h_5899_67 ErbB2_ErbB3_neuregulin_1_beta_1act_integral_to_membrane_v1 red red red grey red grey grey red grey grey blue _h_2944_80 not E_cadherin_cytoplasm and (MAPK_14 or p120ctn) blue _h_2944_81 not E_cadherin_cytoplasm and (MAPK_14 or p120ctn) red blue _h_3276 Erk2_1O_1O_1act red red grey blue _h_4112 PDGF_BB_PDGFRB__dimer__1act_integral_to_membrane_v1 blue _h_5333 TCPTP_p45_1act_nucleus grey grey grey grey blue _h_5143 not JUN__dimer__1act_nucleus_v3 grey grey grey grey blue _h_94 TAp73a__tetramer__nucleus_v3 grey red _h_2837 blue GRB2 blue _h_3189_2 IL27_IL27R_JAK2_TYK2_1act grey red red red red _h_1171_1 blue JIP3 blue _h_886 SCF_KIT_1act _h_887 blue CXCL11_extracellular_region and GTP_v1 blue _h_884 ( not MYC_Max_MIZ_1_nucleus) _h_885 blue SMAD3_SMAD4_1act_nucleus grey red grey blue _h_888 EPO_EPOR__dimer__JAK2 _h_889 blue EVI5 blue _h_2434_40 ((EGFR_EGFR_1act_integral_to_membrane_v1 or EGFR_EGFR_EGF_EGF_GRB2_GAB1_1act_integral_to_membrane_v1) and ( not (EGFR_EGFR_1ina_integral_to_membrane or EGFR_EGFR_EGF_EGF_GRB2_GAB1_1ina_integral_to_membrane))) red blue _h_2434_42 ((EGFR_EGFR_1act_integral_to_membrane_v1 or EGFR_EGFR_EGF_EGF_GRB2_GAB1_1act_integral_to_membrane_v1) and ( not (EGFR_EGFR_1ina_integral_to_membrane or EGFR_EGFR_EGF_EGF_GRB2_GAB1_1ina_integral_to_membrane))) blue _h_2434_43 ((EGFR_EGFR_1act_integral_to_membrane_v1 or EGFR_EGFR_EGF_EGF_GRB2_GAB1_1act_integral_to_membrane_v1) and ( not (EGFR_EGFR_1ina_integral_to_membrane or EGFR_EGFR_EGF_EGF_GRB2_GAB1_1ina_integral_to_membrane))) blue _h_2434_44 ((EGFR_EGFR_1act_integral_to_membrane_v1 or EGFR_EGFR_EGF_EGF_GRB2_GAB1_1act_integral_to_membrane_v1) and ( not (EGFR_EGFR_1ina_integral_to_membrane or EGFR_EGFR_EGF_EGF_GRB2_GAB1_1ina_integral_to_membrane))) grey grey blue _h_2434_47 ((EGFR_EGFR_1act_integral_to_membrane_v1 or EGFR_EGFR_EGF_EGF_GRB2_GAB1_1act_integral_to_membrane_v1) and ( not (EGFR_EGFR_1ina_integral_to_membrane or EGFR_EGFR_EGF_EGF_GRB2_GAB1_1ina_integral_to_membrane))) red grey grey grey red red _h_3554 blue Aurora_A blue _h_3555 IL2_IL2R_1act_integral_to_membrane blue _h_3556 Myb_nucleus grey blue _h_3550 IQGAP1 or RAS_family_GTP_1act_plasma_membrane_H_RAS_isoform_1_GTP_v1 or RAS_family_GTP_1act_plasma_membrane_N_RAS_GTP_v1 _h_3551 blue PDGF_PDGFRA_1act _h_3552 blue RET51_GFRalpha1_GDNF_FRS2_membrane_raft and SHP2_cytoplasm blue _h_3553 (G_beta5_gamma2_1act or TGM2_GTP_1act) _h_561 blue duplin_nucleus blue _h_3558 p53__tetramer__nucleus_v2 red red red grey grey red _h_5829_2 blue LPA3_plasma_membrane red red grey red red grey blue _h_2637_6 ((GNB1_GNG2_1act_cytoplasm or PDGF_BB_PDGFRB__dimer__1act_integral_to_membrane_v1) or SDF1_CXCR4_JAK2_1act_integral_to_membrane) grey grey grey grey grey grey grey red _h_5226_1 blue Ephrin_B2_integral_to_membrane _h_5226_2 blue EPHB1_integral_to_membrane grey grey _h_3048 blue CaM_Ca2__Calcineurin_A_alpha_beta_B1_1act_v2 and NFAT4_cytoplasm grey grey blue _h_5818 ((STAT5A_B__dimer__1act_nucleus or STAT5A__dimer__active_1act_nucleus_v2) or STAT5B__dimer__1act_nucleus) red _h_5813 blue Ku_Artemis_DNA_PKcs__dimer__POLL_XRCC4__dimer__Ligase_IV_site_of_double_strand_break _h_5812 blue beta_catenin_nucleus grey _h_5817 blue RAC1_GDP_1ina_v1 and (VAV2_1act_cell_leading_edge or p130CAS_Crk_Dock1_cell_leading_edge) _h_5816 blue Ephrin_B1_EPHB1_2_1act_integral_to_membrane_v2 blue _h_4118 STAT6__dimer__1act_nucleus_v1 blue _h_5814 ( not Mad_Max) grey grey blue _h_1036_14 Arf6_GTP_1act or Arf6_GTP_1act_plasma_membrane blue _h_1036_15 Arf6_GTP_1act or Arf6_GTP_1act_plasma_membrane blue _h_1036_12 Arf6_GTP_1act or Arf6_GTP_1act_plasma_membrane blue _h_1036_13 Arf6_GTP_1act or Arf6_GTP_1act_plasma_membrane blue _h_1036_10 Arf6_GTP_1act or Arf6_GTP_1act_plasma_membrane grey red grey blue _h_1036_19 Arf6_GTP_1act or Arf6_GTP_1act_plasma_membrane _h_3143 blue Aurora_A grey red _h_3140 blue SHC_3O_1act_cytoplasm _h_3147 blue Ephrin_A5_integral_to_membrane grey grey _h_3144 blue Intersectin_N_WASP red _h_3148 blue Ephrin_A1_EPHA4_1act_integral_to_membrane red _h_2620 blue alpha1_beta1_Integrin_integral_to_membrane grey grey grey red _h_254_5 blue PKC_alpha_1act and alpha6_beta4_Integrin_Laminin_hemidesmosome grey grey red blue _h_2702 IKK_beta_1act or NF_kappa_B_RelA_1act_cytoplasm_v1 _h_3044 blue beta_catenin_nucleus red red grey red red _h_2289 blue Sema4a_extracellular_region grey grey grey grey grey red grey grey red grey grey blue _h_1036_106 Arf6_GTP_1act or Arf6_GTP_1act_plasma_membrane grey grey grey red grey red grey blue _h_801 MKK3_1O_1O_1act or MKK6_1O_1O_1act grey blue _h_368 Erk2_1O_1O_1act blue _h_3647 (AR_T_DHT_nucleus and ( not APPL_1act)) red blue _h_1036_24 Arf6_GTP_1act or Arf6_GTP_1act_plasma_membrane grey grey grey grey grey grey grey grey red red grey red grey grey red red _h_4695 blue CBL_1O_1act and CRKL_1O_1act red grey grey _h_2541 blue LPA3_plasma_membrane blue _h_2542 Fyn_1O_1act or LYN_1act_1O or Lck_1O_1act or Src_1act_1O _h_3849 blue Alpha_SP22_1u_1act_1O_1O_cytoplasm and Alpha_Synuclein_1O_1u_1O_1act_cytoplasm and Lipids and Synphilin_1_1u and not Alpha_Synuclein__fragmented__1ina_1O_cytoplasm blue _h_4849 ((STAT5A_B__dimer__1act_nucleus or STAT5A__dimer__active_1act_nucleus_v2) or STAT5B__dimer__1act_nucleus) blue _h_2545 (MITF_nucleus or RB1_nucleus) _h_2546 blue (IKK_beta_cytoplasm and NEMO_1u_cytoplasm) grey grey grey grey blue _h_4970 JUN_ATF2_1act_nucleus red grey red red red grey red _h_3263_69 blue FGFR1b_FGF2_1act _h_4258 blue GATA1_nucleus red red red grey _h_4253 blue Transducin_1ina red blue _h_4251 (E2_ERA_nucleus or FOXA1_nucleus) blue _h_4256 ETA_receptor_Endothelin_1_integral_to_membrane or ROCK2_1act or ROCK_1act grey blue _h_4254 dNp63a__tetramer__nucleus_v2 _h_4255 blue ELK1_2O_1act_nucleus grey grey red grey red grey grey grey blue _h_3825 PKC_beta_1act_plasma_membrane or PKC_delta_1act_plasma_membrane or PKC_epsilon_1act_plasma_membrane or PKC_isoenzymes_1act_plasma_membrane or PKC_theta_1act_plasma_membrane or PRKCG_1act_plasma_membrane or PRKCH_1act_plasma_membrane red grey red red red red _h_4231_1 blue p38_beta_1O_1O_1act _h_1830_2 blue Src_cytoplasm red grey blue _h_375 ATF2_2O_1act grey red red grey red red red blue _h_5251 ((MYC_nucleus or SP1) and ( not (SP1_HDAC2 or SP3_HDAC2))) blue _h_5250 not Cbp_p300_SKP2 and (CBP_nucleus or p300_nucleus) grey blue _h_5252 (( not (SLUG_nucleus or p53__tetramer__nucleus_v7)) and ((GCN5_L_ADA2B_TAF9_nucleus or SP1_3_nucleus) or p53__tetramer__nucleus_v5)) _h_5255 blue (Neutral_sphingomyelinase_II_1act and ( not (((C11AG or EGF_extracellular_region) or GW4869) or Sphingosine_1_phosphate))) grey blue _h_5257 (( not CEBPA_BRM_RB1_E2F4_nucleus) and ((E2F1_3_DP_nucleus_DP1_E2F1 or E2F1_3_DP_nucleus_DP1_E2F2) or E2F1_3_DP_nucleus_DP1_E2F3)) grey grey blue _h_5258 TAp63g__tetramer__1act_nucleus_v2 _h_2264_1 blue C3G_1O and FRS2_family_SHP2_CRK_family_1act_FRS2_family_active_1act_Crk_cytoplasm_SHP2_1O_cytoplasm red blue _h_6041 HIF2A_ARNT_nucleus_v3 _h_6040 blue TRKB_1N_integral_to_membrane grey grey blue _h_6045 p16INK4a or p21CIP1 or p27Kip1 grey grey blue _h_6046 Fibronectin_v1 or RhoA_1act or Syndecan_4_focal_adhesion blue _h_807_14 FASLG_FAS__trimer__Src_Syk_1act_integral_to_membrane or TRAIL__trimer__extracellular_region blue _h_807_15 FASLG_FAS__trimer__Src_Syk_1act_integral_to_membrane or TRAIL__trimer__extracellular_region blue _h_807_16 FASLG_FAS__trimer__Src_Syk_1act_integral_to_membrane or TRAIL__trimer__extracellular_region blue _h_807_17 FASLG_FAS__trimer__Src_Syk_1act_integral_to_membrane or TRAIL__trimer__extracellular_region blue _h_1013 AP2_v1 or beta_Arrestin2 blue _h_807_11 FASLG_FAS__trimer__Src_Syk_1act_integral_to_membrane or TRAIL__trimer__extracellular_region grey red grey grey grey _h_3708 blue HMGB1_TLR2_TLR1_MYD88_TIRAP_1act_integral_to_membrane and IRAK2 and IRAK4 grey red _h_4647_2 blue PDE3B_1act red _h_3700 blue Endoglin__dimer__integral_to_membrane _h_3703 blue GATA2_nucleus blue _h_3702 ( not ATF2_JUND_macroH2A_nucleus) blue _h_3705 Granzyme_B blue _h_3704 Src_1act_1O blue _h_3707 CDC42_GTP_1act_plasma_membrane red grey blue _h_3962 E2_ERA__dimer__JUN_HSF2_CEBPB_1act_nucleus red grey blue _h_4263 NEUROSIN_cytoplasm _h_3503 blue CEBPA_BRM and RB1 blue _h_1891 Erk2_1O_1O_1act grey _h_5092 blue PDGFRB_integral_to_membrane grey grey blue _h_1122 E2F1_DP_PCAF_nucleus red red grey red grey _h_5660 blue MEKK3 grey grey blue _h_5664 Antigen_IgE_Fc_epsilon_R1_LYN_SYK_v2 blue _h_5095 STAT3__dimer___1act_nucleus _h_5666 blue ATR_1act and p53 red _h_5668 blue GTP_v1 and Gq_family_GDP_1ina _h_5669 blue Insulin_Receptor_Insuli_IRS1_GRB2_SHC _h_2084_5 blue YWHAB _h_435 blue IL1_alpha grey _h_1659 blue TRAILR2__trimer__integral_to_membrane red red blue _h_4896 alphaIIb_beta3_Integrin_1act or mu_calpain_1act grey red grey grey red red _h_330 blue GTP_v1 and not RasGAP_p62DOK_SHIP and (PKC_1act or SHC_Grb2_SOS1_1act_v1) red grey grey grey grey grey _h_3455_1 blue YWHAQ blue _h_502 ErbB4_ErbB4_neuregulin_1_beta_neuregulin_1_beta_1act_integral_to_membrane_v2 blue _h_501 MIM_GLI2A_1act_nucleus _h_500 blue Hsp90 and RACK1_Elongin_B_Elongin_C_1act red grey blue _h_505 not NGF__dimer__TRKA_1act_integral_to_membrane and (NGF__dimer__p75_NTR__TRAF6_RIP2_IRAK_p62_Atypical_PKCs_1act_integral_to_membrane or PDK1_PKC_theta_1act or PDK1_PKC_theta_1act_plasma_membrane or PKC_alpha_1act_plasma_membrane or PKC_beta_1act_plasma_membrane or PKC_epsilon_1act_plasma_membrane or PKC_theta_FLNA) blue _h_504 NIK_1act_cytoplasm grey grey blue _h_2284 ( not ((E2F1_3_DP_nucleus_DP1_E2F1 or E2F1_3_DP_nucleus_DP1_E2F2) or E2F1_3_DP_nucleus_DP1_E2F3)) blue _h_333 IL23_IL23R_JAK2_TYK2_1act_integral_to_membrane red red _h_1651 blue H2O and PAO_1act and Spermidine blue _h_4026_2 EGFR_EGFR_EGF_EGF_1act_endosome_v2 blue _h_4026_3 EGFR_EGFR_EGF_EGF_1act_endosome_v2 red blue _h_4026_5 EGFR_EGFR_EGF_EGF_1act_endosome_v2 blue _h_4026_6 EGFR_EGFR_EGF_EGF_1act_endosome_v2 blue _h_4026_7 EGFR_EGFR_EGF_EGF_1act_endosome_v2 grey blue _h_4026_9 EGFR_EGFR_EGF_EGF_1act_endosome_v2 grey red red grey grey blue _h_1655 (AR_T_DHT_nucleus or MAK_1act) grey grey _h_5109_1 blue HDAC2_nucleus and NF_kappa_B1_p50_RelA_Cbp_NF_kappa_B1_p50_CBP_RelA red blue _h_1656 HIF1A_ARNT_nucleus red red red blue _h_6466 IL23_IL23R_JAK2_TYK2_1act_integral_to_membrane red red grey grey red blue _h_6464 p38_alpha_1O_1O_1act_v2 grey grey blue _h_2824 PI_4_5_P2_plasma_membrane _h_4829 blue GMCSF_GMR_alpha_CSF2RB__dimer__1act_integral_to_membrane blue _h_4828 TAp63g__tetramer__SSRP1_1act_nucleus blue _h_4539 HIPK2 _h_4538 blue Fra1_1O_2O_nucleus _h_4537 blue Cholesterol_v2 and HHAT _h_4536 blue BARD1_CSTF1 blue _h_4535 ( not BCL2) grey red blue _h_4532 T_DHT_AR_TIF2_CARM1_nucleus blue _h_4531 Antigen_IgE_Fc_epsilon_R1_LYN_SYK_v2 blue _h_4822 ROCK2_1act or ROCK_1act or myosin_phosphatase_complex_1act grey grey blue _h_2742 TCF1E_beta_catenin_1act_nucleus grey _h_2392_5 blue KSR_1act_plasma_membrane or PP2A_1act_v1 or RAS_family_GTP_1act_plasma_membrane_H_RAS_isoform_1_GTP_v1 or RAS_family_GTP_1act_plasma_membrane_N_RAS_GTP_v1 blue _h_3518 not MYC_Max_nucleus_v4 grey _h_5584 blue alphav_beta8_Integrin_integral_to_membrane red red red grey _h_2815 blue SHP2_1O_cytoplasm and (BDNF__dimer__TRKB_1act_endosome_v2 or NGF__dimer__TRKA_1act_endosome or NT3__dimer__TRKC_1act_endosome or NT_4_5__dimer__TRKB_1act_endosome) grey blue _h_2743 E2F3_DP_TFE3_nucleus red red blue _h_1869 HIF1A_ARNT_nucleus grey blue _h_5583 MYC_Max_Cbp_p300_1act_nucleus_MYC_1O_1u_v2_CBP_Max or MYC_Max_Cbp_p300_1act_nucleus_MYC_1O_1u_v2_p300_Max _h_4846 blue uPAR_plasma_membrane grey red red grey red red _h_3164_2 blue DNA_rna and RARs_THRs_THRs_RAR_alpha grey grey grey _h_1984_1 blue FGFR_FGF_v2 grey red blue _h_5928 PRL_1 or PRL_3 or S1P_S1P2_G12_G13 or S1P_S1P4_G12_G13 grey _h_1535 blue PDGF_PDGFRA_Crk_1act red red red blue _h_3514 S1P_S1P4_Gi blue _h_5322 TCF4_beta_catenin_1act_nucleus blue _h_3515 ErbB2_ErbB3_neuregulin_1_beta_1act grey red grey grey red blue _h_49 p53__tetramer__nucleus_v2 blue _h_48 FOXA1_nucleus _h_1833 blue IRF7 _h_4237 blue HGF_dimer__MET_dimer__1act_integral_to_membrane_v3 blue _h_1835 p53__tetramer__nucleus_v2 _h_1834 blue HDAC_complex_nucleus_v1 and SAP18_nucleus and SIN3a_nucleus and SIN3b_nucleus grey blue _h_1836 FOXM1B_nucleus blue _h_1839 Gamma_Secretase_plasma_membrane_v2 blue _h_1838 p53__tetramer__nucleus_v2 _h_43 blue alpha3_beta1_Integrin_integral_to_membrane red blue _h_45 RAC1_GTP_1act_plasma_membrane grey _h_47 blue JUN_2O_2O_nucleus grey grey red blue _h_3089 not insulin and (FOXA2_nucleus_v1 or Neurofibromin) _h_3086 blue Alpha_Synuclein_1O_cytoplasm grey blue _h_3084 (SMAD3_SMAD4_TFE3_1act_nucleus and ( not SMAD3_SMAD4_Max_1act_nucleus)) blue _h_3085 HES1_JAK2_1act_nucleus blue _h_3082 NFAT1_JUN_FOS_1act_nucleus red red blue _h_3081 FOXO4_2O_nucleus blue _h_5066 FOXO3A_nucleus blue _h_6355 (((((CEBPA_nucleus or CEBPB_nucleus) or CEBPD_nucleus) or CREB1_nucleus) or FOXA3_nucleus) or HNF1A__dimer__nucleus) grey _h_2288 blue 9cRA and PKA_1act red grey blue _h_5061 ((STAT5A_B__dimer__1act_nucleus or STAT5A__dimer__active_1act_nucleus_v2) or STAT5B__dimer__1act_nucleus) _h_2282 blue B_cell_antigen_BCR_complex and CD45_1act and not PAG1_CSK _h_2280 blue FASLG_FAS__trimer__FADD_FADD_1act_integral_to_membrane and c_FLIPS and not (cIAP1 or cIAP2) blue _h_2287 HIF1A_ARNT_nucleus _h_2286 blue HIF2A_1h_3N_cytoplasm grey blue _h_5069 Myb_nucleus _h_1956 blue (LRP6_integral_to_membrane and (FZD8_integral_to_membrane or WNT3A_2N_1S_1O_extracellular_region)) blue _h_1957 FOXO3A_nucleus blue _h_1954 TAp73a__tetramer__nucleus_v3 blue _h_6356 TXA2_TXA2_R_family_1act_integral_to_membrane or alphaV_beta3_Integrin_Osteopontin _h_1952 blue BORA_1O grey blue _h_1950 Myb_nucleus blue _h_1951 Akt1_1O_1act_1O_1O_plasma_membrane or CDC42_GTP_1act_plasma_membrane or PI3K_1act_plasma_membrane_v1 or PI_3_4_5_P3_plasma_membrane or Phosphatidic_acid_plasma_membrane_v2 grey blue _h_5311 Caspase_2_1act or Caspase_6_1act blue _h_3223_1 Lethal_Factor_cytoplasm and not Epigallocatechin_3_gallate__EGCG_ blue _h_6013_2 RAC1_GTP_1act_v1 blue _h_1958 Erk1_1O_1act_1O_cytoplasm or Erk1_1O_1act_1O_nucleus or Erk2_1O_1O_1act_cytoplasm or Erk2_1O_1O_1act_nucleus _h_6350 blue BRCA1_CtBP_CtIP blue _h_3886 ITCH or WWP1 blue _h_3887 GRK3 _h_3884 blue ATF2_2O_1act_nucleus blue _h_3885 E_cadherin_Ca2__beta_catenin_alpha_catenin_p120_catenin_cell_cell_junction_v1 grey grey red _h_3881 blue AR red red blue _h_6352 (AR_T_DHT_nucleus or PIAS1) _h_3888 blue SHP2_1ina_cytoplasm _h_3889 blue Antigen and IgE and LYN_plasma_membrane and Syk red red grey red _h_1320 blue BRCA1_BARD1 red blue _h_5392 HES1_RB1_RUNX2_1act_nucleus _h_5393 blue Ca2__extracellular_region red blue _h_5395 (PDGF_BB_PDGFRB__dimer__1act_integral_to_membrane_v1 or S1P_S1P3_Gi) _h_5397 blue Dok_R _h_5398 blue PDGFRB_integral_to_membrane _h_6359 blue ER_alpha_nucleus grey red red red blue _h_1480 Caspase_8__tetramer__1act _h_1481 blue Necl_5__dimer_ and PDGF_BB_PDGFRB__dimer__1act_integral_to_membrane_v1 blue _h_1482 (((((((p38_alpha_1O_1O_1act_v2 or p38_beta_1O_1O_1act) or p38alpha_beta_CK2_1act__alpha_2__beta_2CK2_1act_p38_alpha_1O_1O_1act_v2) or p38alpha_beta_CK2_1act__alpha_2__beta_2CK2_1act_p38_beta_1O_1O_1act) or p38alpha_beta_CK2_1act__alpha___alpha_prime___beta_2_CK2_1act_p38_alpha_1O_1O_1act_v2) or p38alpha_beta_CK2_1act__alpha___alpha_prime___beta_2_CK2_1act_p38_beta_1O_1O_1act) or p38alpha_beta_CK2_1act__alpha_prime_2__beta_2_CK2_1act_p38_alpha_1O_1O_1act_v2) or p38alpha_beta_CK2_1act__alpha_prime_2__beta_2_CK2_1act_p38_beta_1O_1O_1act) _h_1483 blue Fer_Fyn_1act blue _h_1484 PIP5K1A_1act blue _h_419_2 RHOA_GTP_1act_plasma_membrane grey grey blue _h_1488 Exportin_1_Ran_NUP214 blue _h_1489 GSK3beta_nucleus grey red grey red blue _h_807_37 FASLG_FAS__trimer__Src_Syk_1act_integral_to_membrane or TRAIL__trimer__extracellular_region grey red red grey grey blue _h_1009 Vav3_1act_1O blue _h_1322 ( not MYC_Max_nucleus_v4) blue _h_4046 not STXBP4 and (Fbw7_gamma or RACK1) blue _h_2699 E2F1_DP_nucleus_v2 or SP1 grey red blue _h_5233 PRL_1 grey _h_2952 blue CDK2 grey grey grey grey red grey grey _h_4506 blue alphav_beta3_Integrin_integral_to_membrane red blue _h_5232 Dynamin_2_GTP_1act_cell_cell_junction or RAB5_GTP_1act_v2 grey grey grey _h_2027 blue ((((ARAP2_1act or Ephrin_A1_EPHA2_NCK1_GIT1_1act_cell_cell_junction) or GIT1_1act) or PI_3_4_5_P3) or PI_4_5_P2) blue _h_2754 E2F4_DP2_GCN5_nucleus blue _h_2025 GSK3beta_1act and not GSK3beta_1ina_1O _h_2024 blue TGFB1__dimer__1act_extracellular_region and TGFBR2__dimer__1act_integral_to_membrane red red _h_2753 blue HMOX1 blue _h_2020 Histone_H3_2O grey red grey grey grey grey red red grey red blue _h_1226 CRKL_1act_cytoplasm grey red blue _h_1221 HIF1A_ARNT_nucleus blue _h_1222 MYOD_nucleus or RB1_E2F1_3_DP_nucleus_v3_DP1_E2F1_RB1 or RB1_E2F1_3_DP_nucleus_v3_DP1_E2F3_RB1 or RB1_E2F1_3_DP_nucleus_v3_DP1_RB1_E2F2 blue _h_1223 GSK3beta_1O_1act grey grey _h_1228 blue Aurora_B _h_1229 blue (Dynamin_2_GDP_1ina_cell_cell_junction and NME1_1act_cell_cell_junction) blue _h_1004 Fyn_1O_1act or LYN_1act_1O or Lck_1O_1act or Src_1act_1O red _h_2360 blue alpha4_beta1_Integrin_integral_to_membrane_v1 grey blue _h_3498 (E2F1_DP_nucleus_v4 and ( not KAP1)) grey grey _h_3909 blue RhoA_GDP_1ina grey blue _h_2667 FOXA2_nucleus_v1 grey blue _h_3495 SRF__dimer__Myocardin_1act_nucleus and not ELK1_SRF_1act_nucleus_v2 grey blue _h_1326 Ca2__v1 or LIS1_IQGAP1 red _h_3494 blue TRKA_1N_integral_to_membrane red grey _h_2713_3 blue SMAD8A_2O_1act_cytoplasm grey grey _h_1219_1 blue NRIP1 and RXRs_RARs_RXR_alpha_Rar_gamma1 and SMRT__N_CoR2_ and (Akt1_1O_1act_1O_1O_plasma_membrane or Erk2_1O_1O_1act) red red grey blue _h_4419_2 Gq_family_GTP_1act red _h_1329 blue (Gi_family_GNB1_GNG2_GDP and ((AR_T_DHT_plasma_membrane or DHT_plasma_membrane) or testosterone_plasma_membrane)) blue _h_4419_1 Gq_family_GTP_1act red grey grey blue _h_2610 E2_ERA__dimer__AIB1_1act_nucleus grey grey grey _h_3263_6 blue FGFR1c_FGF2_1act red grey _h_3263_5 blue FGFR1b_FGF1_1act grey _h_3263_3 blue FGFR1c_FGF5_1act grey _h_3263_1 blue FGFR1b_FGF1_1act red red red grey red blue _h_2727 (( not Myb_2s_nucleus) and (((BRM_CEBP_nucleus_CEBPA_BRM or BRM_CEBP_nucleus_CEBPB_BRM) or BRM_CEBP_nucleus_CEBPD_BRM) or Myb_nucleus)) grey grey _h_319 blue HES1_nucleus _h_316 blue IRAK_TOLLIP_1ina _h_317 blue CDK5_1O_1act red grey blue _h_312 ((NFAT1_1O_7O_2s_1act_nucleus or NFAT4_1act_nucleus) or NFATc_1act_nucleus) blue _h_313 (Myb_nucleus and ( not SKI_SIN3a_NCoR1_TIF1B_Myb_nucleus)) blue _h_311 TAp63g__tetramer__1act_nucleus_v2 _h_4750 blue GRB2 and RET51_GFRalpha1_GDNF_SHC grey grey grey red _h_5929 blue LRP8_plasma_membrane and RELN_extracellular_region and not LRPAP1_LRP8 blue _h_3578 (RAC1_GTP_1act_plasma_membrane or S1P1_S1P_1act_v1) blue _h_3579 NF_Y and not MYC_Max_NF_Y_nucleus grey grey blue _h_3575 Fra1_JUN_1act_nucleus blue _h_3572 E_cadherin_Ca2__beta_catenin_alpha_catenin_p120_catenin_cell_cell_junction_v1 or RAC1_GTP_1act_cell_cell_junction blue _h_3573 TAp73a__tetramer__nucleus_v3 blue _h_3570 MYC_Max_nucleus_v2 grey grey red red grey red grey red grey blue _h_3953 Caspase_3__tetramer__1act red blue _h_1787 TAp63b__tetramer__1act_nucleus_v1 red grey grey red grey grey grey grey _h_178_1 blue FOS_3O_1O_1act_nucleus and JUN_2O_1act_nucleus and NFATc_1act_nucleus _h_178_3 blue FOS_3O_1O_1act_nucleus and NFAT4_1act_nucleus and p21SNFT_nucleus _h_178_2 blue JUN_2O_1act_nucleus and NFAT1_1O_7O_2s_1act_nucleus and p21SNFT_nucleus grey grey blue _h_3506 HIF1A_ARNT_nucleus grey blue _h_4233_6 Ephrin_B1_EPHB1_2_1act_integral_to_membrane_v1 grey _h_5834 blue Crk_p130_Cas_Paxillin_v2 and p70S6K_1act _h_5837 blue K___cytoplasm and (NCKX1 or NCKX2__SLC24A2_) blue _h_5836 CASR_1act_integral_to_membrane or RHOA_GTP_1act blue _h_5831 SGK1_1O_1O_1act_nucleus grey _h_5833 blue Type_II_Collagen_extracellular_region _h_5832 blue alphaL_beta2_Integrin_integral_to_membrane grey grey blue _h_4233_1 Ephrin_B1_EPHB1_2_1act_integral_to_membrane_v1 red grey red blue _h_6172_4 DAG_v2 grey blue _h_6172_6 DAG_v2 blue _h_6172_7 DAG_v2 blue _h_6172_1 DAG_v2 blue _h_6172_2 DAG_v2 blue _h_6172_3 DAG_v2 red grey red grey grey grey blue _h_3168 NFAT1_c_4_1act_nucleus red red blue _h_3167 not (Gab1_1O_1act_cytoplasm or PTEN_1act_cytoplasm) and (EGFR_PI3K_beta_Gab1_plasma_membrane or PI3K_1act_plasma_membrane_v2 or PI3K_Class2_beta_polypeptide_plasma_membrane) _h_3166 blue RAB5_GDP_1ina_endosome grey red grey blue _h_1784 p53__tetramer__nucleus_v2 grey _h_6096 blue 14_3_3_E grey red red _h_5101 blue RBPJ_NICD_1act_nucleus blue _h_5374 ((CEBPB or SPI1) or STAT6__dimer__1act_nucleus_v1) red red grey grey _h_3581_1 blue (Fra1 and JUNB) grey _h_3581_2 blue JUNB and NFATc_1act_nucleus red red grey grey grey red blue _h_5430 Fbw7_alpha_USP28 or Fbw7_gamma grey _h_1621_2 blue IRS2 grey blue _h_4265 afadin_SHP2_1act blue _h_6101 NUMB_ITCH _h_3505 blue Smad3_1O_1act grey blue _h_1036_39 Arf6_GTP_1act or Arf6_GTP_1act_plasma_membrane grey grey blue _h_1036_30 Arf6_GTP_1act or Arf6_GTP_1act_plasma_membrane blue _h_1036_31 Arf6_GTP_1act or Arf6_GTP_1act_plasma_membrane red blue _h_1036_33 Arf6_GTP_1act or Arf6_GTP_1act_plasma_membrane blue _h_1036_34 Arf6_GTP_1act or Arf6_GTP_1act_plasma_membrane blue _h_1036_35 Arf6_GTP_1act or Arf6_GTP_1act_plasma_membrane blue _h_1036_36 Arf6_GTP_1act or Arf6_GTP_1act_plasma_membrane red red red grey red _h_117 blue CaM and DAG_v2 red grey grey grey blue _h_569 DAG_v2 or IL2_IL2R_alpha_beta_gamma_JAK1_LCK_JAK3_1act_integral_to_membrane blue _h_5432 ETA_receptor_Endothelin_1_integral_to_membrane and not Ca____cytoplasm grey blue _h_2569 SIK1_14_3_3_family_cytoplasm_SIK1_1O_1act_14_3_3_E or SIK1_14_3_3_family_cytoplasm_SIK1_1O_1act_YWHAG or SIK1_14_3_3_family_cytoplasm_SIK1_1O_1act_YWHAQ or SIK1_14_3_3_family_cytoplasm_SIK1_1O_1act_YWHAS or SIK1_14_3_3_family_cytoplasm_SIK1_1O_1act_YWHAZ or SIK1_14_3_3_family_cytoplasm_YWHAB_SIK1_1O_1act or SIK2_1O_1act_cytoplasm or SIK3_14_3_3_family_cytoplasm_14_3_3_E_SIK3_1O_1act or SIK3_14_3_3_family_cytoplasm_SIK3_1O_1act_YWHAQ or SIK3_14_3_3_family_cytoplasm_SIK3_1O_1act_YWHAS or SIK3_14_3_3_family_cytoplasm_SIK3_1O_1act_YWHAZ or SIK3_14_3_3_family_cytoplasm_YWHAB_SIK3_1O_1act or SIK3_14_3_3_family_cytoplasm_YWHAG_SIK3_1O_1act red grey blue _h_2563 PLK3 blue _h_2560 IL23_IL23R_JAK2_TYK2_1act_integral_to_membrane red grey blue _h_2397 Akt1_1O_1act_1O_1O_plasma_membrane blue _h_2729 CIN85_Endophilin_CBL blue _h_2565 not MYC_Max_nucleus_v4 red _h_1243 blue SHP2 red blue _h_2391 YB_1 blue _h_2604 STAT6__dimer__1act_nucleus_v1 grey grey grey blue _h_5465_1 (p38_alpha_1O_1O_1act_v2 or p38_beta_1O_1O_1act) grey red red red red _h_1240 blue mTORC1_PRAS40_DEPTOR_1ina_perinuclear_region_of_cytoplasm grey grey grey grey grey red _h_4886_1 blue CXCL4 and CXCR3_B_integral_to_membrane red grey grey _h_1140 blue NPC and SUMO1_cytoplasm grey grey red red red grey blue _h_3511 not netrin_1_UNC5B_1act_integral_to_membrane red grey red red blue _h_3901 GLI1_1act_nucleus grey grey red blue _h_5436 Gamma_Secretase_1act grey red grey _h_2239_1 blue WDR5 blue _h_5239 HIF1A_ARNT_nucleus blue _h_5238 Fra1_JUND_1act_nucleus blue _h_4059_2 (((((((((((CD40_CD40L__trimer__TRAF2__trimer__integral_to_membrane or MKK4_1O_1O_1act) or MKK4_1act) or MKK7_1act) or RAC1_CDC42_GTP_1act) or RAC1_GTP_1act_v2) or RAL_GTP_1act) or ceramide) or p75_NTR__beta_APP_1act) or proBDNF__dimer__p75_NTR__Sortilin_TRAF6_NRIF_1act_integral_to_membrane) or proNGF__dimer__p75_NTR__Sortilin_NRAGE_1act_integral_to_membrane) or proNGF__dimer__p75_NTR__Sortilin_TRAF6_NRIF_1act_integral_to_membrane) _h_4983 blue (IGF_1R_heterotetramer and ( not E_cadherin_Ca2__beta_catenin_alpha_catenin_p120_catenin_cell_cell_junction_v1)) _h_1142 blue CBL_CRKL_1act_cytoplasm red grey grey _h_3654_1 blue Src_family_SYK_family_BLNK_LAT_1act_SYK_Family_Kinases_active_1act_LAT_10O_1act_Fyn_1O_1act _h_5236 blue CSK blue _h_392 mTOR_1act blue _h_5234 Caspase_6_1act or TNF_alpha_extracellular_region blue _h_1039 FGFR_FGF_Syndecan_2_1act _h_1038 blue Fibronectin_v2 _h_6029 blue IP3_Receptors_1act and TRPC2 blue _h_6028 not Ca2__v1 grey _h_1031 blue IRAK4 and not IL1_beta_fragment_IL1R1_IL1RAP_MYD88s_1act_integral_to_membrane _h_1030 blue Aurora_B and PP1_gamma_chromatin _h_1033 blue Syndecan_4 and Thy1 grey blue _h_1035 E4ICDs_1act_5O_nucleus _h_4552_1 blue E2F4_DP2_p107_p130_nucleus_DP2_p107_E2F4 blue _h_1037 Lethal_Factor_cytoplasm blue _h_6024 ATF2_JUNB_1act_nucleus red _h_3762 blue SMAD3_SMAD4_1act_nucleus blue _h_3761 TAp63b__tetramer__1act_nucleus_v1 _h_3760 blue ((GTP_v1 and ( not Ca2__v1)) and (((((Ca2__v1 or CaM) or CalDAG_GEF1_1act_plasma_membrane) or DAG_v2) or RASGRF2_1act) or RASGRP1_1act)) grey _h_3766 blue IL5RA_Syntenin _h_3765 blue alpha2_beta1_Integrin_integral_to_membrane _h_3764 blue HDAC5_nucleus _h_1244 blue FGFR_FGF_Syndecan_2_1act _h_3769 blue TRIF red blue _h_4056 MYC_Max_TRRAP_GCN5_STAF65G_SPT3_TAF9_TAF10_TAF12_core_Mediator_nucleus grey red red grey grey grey red blue _h_4052 ((AIB1_nucleus or E2_ERA_nucleus) or FOXA1_nucleus) red red _h_966 blue 9cRA and PKA_1act red grey red red blue _h_4922 ATM or ATR grey _h_211 blue VEGFR1_homodimer_plasma_membrane grey grey grey blue _h_2283_2 ROCK2_1act or ROCK_1act red blue _h_5648 TAp63g__tetramer__1act_nucleus_v2 red grey _h_5642 blue IL18 blue _h_5643 TAp63a__tetramer__1act_nucleus_v3 red red grey _h_5644 blue PTCH1_integral_to_membrane blue _h_5645 DNM1 or beta_Arrestin1 _h_1759_2 blue Ephrin_B3_integral_to_membrane _h_1759_3 blue Ephrin_B2_integral_to_membrane grey _h_1759_1 blue Ephrin_B1_integral_to_membrane blue _h_4553 ((IL18_IL18R_1act or IL2) or IL23_IL23R_JAK2_TYK2_1act_integral_to_membrane) grey red grey red grey grey red grey grey grey grey grey _h_1365 blue IL23_IL23R_JAK2_TYK2_1act_integral_to_membrane grey red grey red blue _h_1772 FOXA3_v1 or NFI red blue _h_1077 APAF_1_Caspase_9_1act or Caspase_8__4_units__1act grey red blue _h_780 FOSB_MAFG_1act_nucleus _h_783 blue (GTP_v1 and (GNB1_GNG2_1act_cytoplasm or SDF1_CXCR4_VAV1_1act_cell_leading_edge)) blue _h_782 ATF2_c_Jun_1act_nucleus _h_785 blue (GTP_v1 and IL8_CXCR2_1act_integral_to_membrane_v1) blue _h_784 MYC_Max_nucleus_v2 blue _h_787 Caspase_6_1act blue _h_786 GLI3A_Cbp_1act_nucleus blue _h_789 ( not MYC_Max_MIZ_1_nucleus) _h_3840_5 blue CDK4_6_Cyclin_D_CDK4_Cyclin_D3 _h_1364 blue GSK3beta_1ina_1O_cytoplasm red red grey red red grey blue _h_77 not iASPP and (DYRK2_1act_nucleus or HIPK2_nuclear_body or PKC_delta or p38_alpha_1O_1O_1act_v2) grey _h_2403 blue DLK1_integral_to_membrane _h_1778 blue FADD and sTNF_alpha_TNFR1A_TRADD_STAT1__dimer__1act_integral_to_membrane grey grey grey _h_4923 blue PDGFRA_integral_to_membrane and PDGFRB_integral_to_membrane _h_1779 blue USF2_nucleus red grey grey grey grey _h_4510 blue HRAS_1act_plasma_membrane _h_4512 blue not MAGP_2 grey grey red red blue _h_2659_1 ROCK2_1act or ROCK_1act grey blue _h_2944_17 not E_cadherin_cytoplasm and (MAPK_14 or p120ctn) grey grey red blue _h_2412 IL2_IL2R_alpha_beta_gamma_JAK1_LCK_JAK3_1act_integral_to_membrane _h_1848 blue Akt1_1O_1act_1O_1O_plasma_membrane or CARD11_BCL10_MALT1_TAK1_1act or PKC_beta_6O_2O_1act or TRAF6 _h_1263 blue FOXO1_1act_1N_nucleus and Lysophosphatidic_acid and SIRT1_nucleus _h_2177 blue PLGF2__dimer__extracellular_region grey red red red _h_127 blue SHC_3O_1act_cytoplasm grey _h_121 blue DP2_nucleus blue _h_120 Antigen_IgE_Fc_epsilon_R1_LYN_SYK_v2 or Ca2__cytoplasm blue _h_123 CEBPB_1O_1act grey grey grey _h_129 blue KIDINS220_1act _h_128 blue SFTPA1_extracellular_region and TLR2_integral_to_membrane red _h_1227 blue JUN_2O_2O_nucleus grey grey red grey grey grey _h_3600 blue cIAP1_cIAP2 grey blue _h_3273 Antigen_IgE_Fc_epsilon_R1_LYN_SYK_v2 blue _h_66_6 Ran_GTP_Exportin_1 red red grey grey red _h_6346 blue IL1RA and IL1_alpha _h_65 blue HES6_nucleus blue _h_64 HIF1A_ARNT_nucleus blue _h_63 MYC_Max_nucleus_v2 red blue _h_61 p38_alpha_1O_1O_1act_v2 or p38_beta_1O_1O_1act grey grey blue _h_3604 Myb_nucleus red grey red grey _h_3691_1 blue p38_alpha_1O_1O_1act_v2 _h_1859 blue Sortilin and proNGF__dimer__extracellular_region blue _h_1036_104 Arf6_GTP_1act or Arf6_GTP_1act_plasma_membrane blue _h_3606 ABI1_N_WASP red red blue _h_3279 LPA_LPA2 or Src_1O_1act_plasma_membrane red grey grey red grey blue _h_1036_102 Arf6_GTP_1act or Arf6_GTP_1act_plasma_membrane _h_3691_2 blue MKP7_1act blue _h_1157 PLK1_1O_1act grey blue _h_5051_5 (RAS_family_GTP_1act_plasma_membrane_H_RAS_isoform_1_GTP_v1 or RAS_family_GTP_1act_plasma_membrane_N_RAS_GTP_v1) blue _h_5001 mTORC2_1act blue _h_5002 PKC_cytoplasm blue _h_5051_6 (RAS_family_GTP_1act_plasma_membrane_H_RAS_isoform_1_GTP_v1 or RAS_family_GTP_1act_plasma_membrane_N_RAS_GTP_v1) red blue _h_5005 ( not MYC_Max_nucleus_v4) grey blue _h_5007 JNK2_1O_1O_1act or Jnk1_1O_1act_1O or p38_gamma_1O_1O_1act blue _h_5008 (E2_ERA__dimer__1act_nucleus and ( not ERA_MRF1_nucleus)) blue _h_5009 LIMK1_1act or LIMK2_1act blue _h_3255 LEF1_beta_catenin_CDX1_1act_nucleus blue _h_5051_9 (RAS_family_GTP_1act_plasma_membrane_H_RAS_isoform_1_GTP_v1 or RAS_family_GTP_1act_plasma_membrane_N_RAS_GTP_v1) blue _h_5051_8 (RAS_family_GTP_1act_plasma_membrane_H_RAS_isoform_1_GTP_v1 or RAS_family_GTP_1act_plasma_membrane_N_RAS_GTP_v1) red red blue _h_1930 JNK2_1O_1O_1act or Jnk1_1O_1act_1O or p38_alpha_1O_1act_1O_nucleus or p38_beta_1O_1act_1O_nucleus blue _h_1932 ((STAT5A_B__dimer__1act_nucleus or STAT5A__dimer__active_1act_nucleus_v2) or STAT5B__dimer__1act_nucleus) _h_1933 blue Laminin_8_basement_membrane red blue _h_1935 FOXA1_nucleus _h_1936 blue alpha1_beta1_Integrin_Type_I_Collagen_1act_plasma_membrane red red _h_2681_1 blue NFAT4_1act_nucleus red _h_2608 blue ACTR2A__dimer__integral_to_membrane and Activin_A_extracellular_region grey grey red red _h_3732 blue PrPc_Cu2__plasma_membrane red blue _h_364 Ca2__extracellular_region blue _h_5253 Digestive_enzymes_endosome grey red red grey grey grey grey grey _h_1825 blue SHP1 red grey blue _h_66_3 Ran_GTP_Exportin_1 blue _h_5038 PLK1_1O_1act grey red _h_3263_62 blue FGFR1b_FGF2_1act red red _h_3263_65 blue FGFR1c_FGF1_1act grey grey grey grey grey grey red red _h_3263_66 blue FGFR1b_FGF1_1act blue _h_3472_2 RHOA_GTP_1act_plasma_membrane _h_1307 blue RasGAP red grey blue _h_1552 PLK3 grey grey grey _h_5509_2 blue CRY2_cytoplasm _h_5509_1 blue CRY2_cytoplasm red blue _h_1550 SPI1 or cortisol_GR_alpha__monomer__nucleus grey red red _h_1551 blue Laminin_alpha3 and alpha2_beta1_Integrin grey blue _h_4359 Alpha_Synuclein__Aggregates_ grey _h_4357 blue IRS1 and RET9_GFRalpha1_GDNF _h_4356 blue HDAC4_nucleus blue _h_4355 E2F1_DP_nucleus_v4 red grey blue _h_4352 HPV_16_E6_E6AP red _h_4350 blue (RXR_alpha and VDR_VDR_DNA) _h_6262 blue STAT5A__dimer__active_1act_cytoplasm blue _h_6274 Erk2_1O_1O_1act or KSR_1act_plasma_membrane red grey blue _h_6275 STAT3__dimer__active_1act_v1 _h_1741 blue IL1_beta_fragment_IL1R1_IL1RAP_MYD88_IRAK4_IRAK_TOLLIP_1act_integral_to_membrane red grey grey grey blue _h_2004 ATM blue _h_2007 FOXA2_nucleus_v1 grey blue _h_2008 Gamma_Secretase_plasma_membrane_v1 blue _h_1305 Caspase_2_1act or Caspase_3_1act grey grey _h_4732 blue MAPK8IP1_MKK7_MAP3K11_JNK1 red grey red grey blue _h_1209 FGFR_FGF2_complex blue _h_1206 HIF1A_ARNT_nucleus grey blue _h_1204 ((JUN_FOSNFAT1_c_4_1act_nucleus_c_Jun_2O_NFAT1_1O_7O_2s_1act_nucleus_FOS_1O_1O or JUN_FOSNFAT1_c_4_1act_nucleus_c_Jun_2O_NFAT4_1act_nucleus_FOS_1O_1O) or JUN_FOSNFAT1_c_4_1act_nucleus_c_Jun_2O_NFATc_1act_nucleus_FOS_1O_1O) _h_1205 blue LYN red blue _h_5899_26 ErbB2_ErbB3_neuregulin_1_beta_1act_integral_to_membrane_v1 _h_1200 blue S1P1_Sphingosine_1_phosphate_1act_plasma_membrane grey red blue _h_5899_27 ErbB2_ErbB3_neuregulin_1_beta_1act_integral_to_membrane_v1 _h_1246_1 blue ((CTHRC1_trimer_ and FZD6_integral_to_membrane) and ROR2_integral_to_membrane) blue _h_5899_20 ErbB2_ErbB3_neuregulin_1_beta_1act_integral_to_membrane_v1 red blue _h_868 RXRs_LXRs_DNA_Oxysterols_1act_v2 blue _h_2460 Btk_1act_2O_plasma_membrane or NTAL_PLCgamma1_GRB2_SLP76_GADs or VAV1_1act_1O blue _h_5899_21 ErbB2_ErbB3_neuregulin_1_beta_1act_integral_to_membrane_v1 grey blue _h_3189_4 IL27_IL27R_JAK2_TYK2_1act grey red grey grey _h_1901 blue APC_nucleus grey blue _h_5899_23 ErbB2_ErbB3_neuregulin_1_beta_1act_integral_to_membrane_v1 _h_944 blue ICAM1 grey grey grey grey grey blue _h_4734 TCR_CD3_MHC_I_CD8_LCK_ZAP_70_1act_integral_to_membrane red red red red grey red red blue _h_5899_3 ErbB2_ErbB3_neuregulin_1_beta_1act_integral_to_membrane_v1 grey grey blue _h_5899_2 ErbB2_ErbB3_neuregulin_1_beta_1act_integral_to_membrane_v1 blue _h_16 LKB1_MO25_STRADA_STRADB_cytoplasm_v1 grey grey blue _h_5899_5 ErbB2_ErbB3_neuregulin_1_beta_1act_integral_to_membrane_v1 _h_1141_2 blue GRB7 grey _h_2894_11 blue FOXO3A_1O_1ina_2O_nucleus red _h_1141_1 blue GRB7 blue _h_384 MYC_Max_nucleus_v2 blue _h_2758_2 (BMP2_4_BMPR2_BMPR1A_1B_RGM_XIAP_1act_integral_to_membrane and ( not TAK1_SMAD6)) grey blue _h_2758_1 (BMP2_4_BMPR2_BMPR1A_1B_RGM_XIAP_1act_integral_to_membrane and ( not TAK1_SMAD6)) grey red red blue _h_5899_8 ErbB2_ErbB3_neuregulin_1_beta_1act_integral_to_membrane_v1 _h_381 blue CDC42_GTP_1act_plasma_membrane red grey red grey _h_339 blue Fibronectin_alpha4_beta1_Integrin_cell_leading_edge_v2 and paxillin_cytoplasm blue _h_2411 B7_family_CD28_1act_integral_to_membrane_v2 red grey red grey _h_331 blue (MIZ_1_cytoplasm and p300) blue _h_332 NT3__dimer__TRKC_1act_integral_to_membrane _h_2894_16 blue FOXO4_1O_1ina_2O_nucleus blue _h_2637_9 GNB1_GNG2_1act_cytoplasm or PDGF_BB_PDGFRB__dimer__1act_integral_to_membrane_v1 or SDF1_CXCR4_JAK2_1act_integral_to_membrane blue _h_335 (( not ((E_cadherin_cytoplasm or Endoglin__dimer__beta_Arrestin2_endosome) or MKP_3)) and (((((((((((((((((((((((((((((((((((((((((((((((((((Arf6_GTP_1act or BRAF_1act) or Ca2__cytoplasm) or ErbB4_ErbB4_neuregulin_1_beta_neuregulin_1_beta_GRB2_SHC_1act_membrane_raft) or FGF2_extracellular_region) or FGFR1_FGF_complex_Syndecan_4_endocytic_vesicle) or FGFR_FGF2_complex) or IGF_1R_heterotetramer_IGF1_IRS1) or IL2_extracellular_region) or IQGAP1) or JAM_A) or KSR_14_3_3__dimer__MEK1_2_active_1act_plasma_membrane_v2_14_3_3_E_MEK1_2_active_1act_KSR_1O) or KSR_14_3_3__dimer__MEK1_2_active_1act_plasma_membrane_v2_MEK1_2_active_1act_KSR_1O_YWHAS) or KSR_14_3_3__dimer__MEK1_2_active_1act_plasma_membrane_v2_MEK1_2_active_1act_YWHAQ_KSR_1O) or KSR_14_3_3__dimer__MEK1_2_active_1act_plasma_membrane_v2_MEK1_2_active_1act_YWHAZ_KSR_1O) or KSR_14_3_3__dimer__MEK1_2_active_1act_plasma_membrane_v2_YWHAB_MEK1_2_active_1act_KSR_1O) or KSR_14_3_3__dimer__MEK1_2_active_1act_plasma_membrane_v2_YWHAG_MEK1_2_active_1act_KSR_1O) or KSR_1act_plasma_membrane) or Lethal_Factor_cytoplasm) or MEK1_2O_1act) or MEK1_2O_1act_cytoplasm) or MEK1_2_active_1act) or MEK1_MEK2_v2) or MEK2_2O_1act) or MEK2_2O_1act_cytoplasm) or NGF__dimer__TRKA_MATK_1act_endosome) or NIK_1act_cytoplasm) or PKC_1act) or PKC_alpha_1act) or PKC_alpha_1act_plasma_membrane) or PKC_beta2_1act_plasma_membrane) or PLD_1act) or PRL_3) or RAF1_1act) or RAP1A_GTP_1act) or RhoA_1act) or S1P1_S1P_Gi_1act_GNAI1_1act_S1P1_1act_S1P_extracellular_region) or S1P1_S1P_Gi_1act_GNAI2_1act_S1P1_1act_S1P_extracellular_region) or S1P1_S1P_Gi_1act_GNAI3_1act_S1P1_1act_S1P_extracellular_region) or S1P1_S1P_Gi_1act_GNAO1_1act_S1P1_1act_S1P_extracellular_region) or S1P1_S1P_Gi_1act_GNAZ_1act_S1P1_1act_S1P_extracellular_region) or S1P_S1P2_Gi) or S1P_S1P3_Gi) or S1P_S1P4_Gi) or SHC_GRB2_SOS1_1act_plasma_membrane) or STAT1__dimer__1act_nucleus_v4) or Syndecan_1_CD147) or Syndecan_2_GM_CSF) or TGFB1__dimer__1act_extracellular_region) or TRAIL__trimer__extracellular_region) or alphav_beta3_Integrin) or alphav_beta3_Integrin_JAM_A)) blue _h_336 PTP1B_plasma_membrane _h_337 blue 14_3_3_E grey grey _h_2894_18 blue YWHAB_nucleus grey blue _h_5585 beta_catenin_MED12_1act_nucleus blue _h_3519 Src_1act_1O red blue _h_5586 GLUT4_plasma_membrane blue _h_5580 JUN_ATF2_1act_nucleus grey red blue _h_3510 (( not insulin) and (FOXA2_nucleus_v1 or Glucocorticoid_Receptor)) red blue _h_5589 Fra1_JUND_1act_nucleus blue _h_5588 SCF_KIT_1act _h_3516 blue ADAP_1O_1act blue _h_3517 TAB1 or TAK1 grey red blue _h_4738 NFAT1_1O_4O_2s_1act_nucleus grey blue _h_719 (AR_T_DHT_nucleus or JHDM2A) grey grey _h_3315 blue alpha4_beta1_Integrin_integral_to_membrane_v1 red grey red red red blue _h_2434_30 ((EGFR_EGFR_1act_integral_to_membrane_v1 or EGFR_EGFR_EGF_EGF_GRB2_GAB1_1act_integral_to_membrane_v1) and ( not (EGFR_EGFR_1ina_integral_to_membrane or EGFR_EGFR_EGF_EGF_GRB2_GAB1_1ina_integral_to_membrane))) grey grey red blue _h_2434_33 ((EGFR_EGFR_1act_integral_to_membrane_v1 or EGFR_EGFR_EGF_EGF_GRB2_GAB1_1act_integral_to_membrane_v1) and ( not (EGFR_EGFR_1ina_integral_to_membrane or EGFR_EGFR_EGF_EGF_GRB2_GAB1_1ina_integral_to_membrane))) blue _h_2434_32 ((EGFR_EGFR_1act_integral_to_membrane_v1 or EGFR_EGFR_EGF_EGF_GRB2_GAB1_1act_integral_to_membrane_v1) and ( not (EGFR_EGFR_1ina_integral_to_membrane or EGFR_EGFR_EGF_EGF_GRB2_GAB1_1ina_integral_to_membrane))) red red grey red red grey red grey grey red grey blue _h_2434_36 ((EGFR_EGFR_1act_integral_to_membrane_v1 or EGFR_EGFR_EGF_EGF_GRB2_GAB1_1act_integral_to_membrane_v1) and ( not (EGFR_EGFR_1ina_integral_to_membrane or EGFR_EGFR_EGF_EGF_GRB2_GAB1_1ina_integral_to_membrane))) _h_2469 blue alpha2_beta1_Integrin_integral_to_membrane grey red blue _h_214 STAT5A_B__dimer__1act_nucleus or STAT5A__dimer__active_1act_nucleus_v2 or STAT5B__dimer__1act_nucleus grey red red blue _h_3911 (( not TGFB1) and ((IL2_extracellular_region or STAT4__dimer__1act_nucleus_v2) or T_bet)) grey blue _h_3433 E2F1_DP_nucleus_v4 grey blue _h_4290_2 LPA_LPA4 grey grey red red red grey blue _h_5352 HGF_dimer__MET_dimer__GAB1_CRK_1act_integral_to_membrane or MEKK1_2O_1act or MKK4_1O_1O_1act_cytoplasm grey grey grey blue _h_861 E2F1_DP_nucleus_v4 grey red blue _h_4982 (( not JNK2_1O_1O_1act) and ((JUN_FOSNFAT1_c_4_1act_nucleus_c_Jun_2O_NFAT1_1O_7O_2s_1act_nucleus_FOS_1O_1O or JUN_FOSNFAT1_c_4_1act_nucleus_c_Jun_2O_NFAT4_1act_nucleus_FOS_1O_1O) or JUN_FOSNFAT1_c_4_1act_nucleus_c_Jun_2O_NFATc_1act_nucleus_FOS_1O_1O)) red _h_4980 blue ACTR2__dimer__integral_to_membrane and Activin_A_extracellular_region _h_4981 blue IL23_IL23R_JAK2_TYK2_1act_integral_to_membrane and STAT3 _h_4986 blue TNF_alpha_TNFR1A_TRADD_MADD_cIAP2_RIP_TRAF2_RAIDD red blue _h_4984 WWOX_1O grey grey blue _h_4988 (IL12_IL12R_TYK2_JAK2_1act_integral_to_membrane or IL27_IL27R_JAK2_TYK2_1act) blue _h_4989 Prolactin_Receptor_Prolactin and not PTP1B_plasma_membrane red grey grey grey grey _h_1100 blue p75_ICD red blue _h_3453 CBP_nucleus or p300_nucleus or p53__tetramer__nucleus_v2 red red red blue _h_1309 CEBPA_nucleus or CEBPB_nucleus or CEBPD_nucleus or FOXA1_nucleus or FOXA2_nucleus_v2 or HNF4_nucleus red blue _h_863 ADAM12 blue _h_1103 (E2_ERA__dimer__1act_nucleus and ( not E2_ERA__dimer__Src_1_MPG_1act_nucleus)) grey red red grey grey grey red _h_6353 blue HMGB1_TLR2_TLR1_1act_integral_to_membrane _h_1813_3 blue EGR4 _h_5309_7 blue alpha6_beta4_Integrin _h_1813_2 blue NFATc_1act_nucleus grey red blue _h_4540_1 Caspase_7_1act red red blue _h_4540_2 Caspase_7_1act red grey red _h_1916 blue LAT_GRAP2_SLP76_VAV1_1act and TCR_CD3_MHC_I_CD8_LCK_1act_integral_to_membrane grey grey grey grey grey blue _h_3435 LKB1_nucleus grey red grey grey grey red grey grey _h_2005_3 blue uPAR_DII_DIII_plasma_membrane grey red red grey grey blue _h_3638 NUP214 and not (SMAD6_7_SMURF1_SMAD1_1ina_SMURF1_SMAD6_SMAD1_1u_1ina_6O or SMAD6_7_SMURF1_SMAD1_1ina_Smad7_SMURF1_SMAD1_1u_1ina_6O) grey _h_1813_1 blue NFAT1_1O_7O_2s_1act_nucleus grey red red red grey grey grey grey red grey red grey blue _h_4294 Jnk1_1O_1act_1O_nucleus grey red red _h_58 blue RHO_2N_2S_1N blue _h_5215 TAp63a__tetramer__1act_nucleus_v3 _h_5214 blue TopBP1 blue _h_5217 Caspase_3__cleaved__1act or Caspase_7__cleaved__1act _h_5216 blue cytochrome_b_245_integral_to_membrane blue _h_5211 (HIF1A_ARNT_Cbp_p300_HDAC7_nucleus_HIF1A_HDAC7a_ARNT_CBP or HIF1A_ARNT_Cbp_p300_HDAC7_nucleus_HIF1A_HDAC7a_ARNT_p300) red grey _h_143 blue TCPTP_p45_nucleus _h_2175_1 blue AIB1 and Cbp_p300_PCAF_nucleus_PCAF_CBP and RAR_alpha red _h_5218 blue Caspase_3_1act red red blue _h_1109 PPP1CB_MYPT1_1act_centrosome _h_1051 blue BCL9 _h_6006 blue PPP2R2A red blue _h_6000 LEF1_beta_catenin_1act_nucleus_v1 _h_1055 blue p52_SHC blue _h_6002 NFAT1_1O_4O_2s_1act_nucleus red red blue _h_1058 IL4_IL4R_JAK1_IL2R_gamma_JAK3_1act_integral_to_membrane _h_6009 blue ARNT_nucleus red red red grey _h_3576 blue p300 and not SIRT1 _h_462 blue FAK_1O_1O_1act_cytoplasm blue _h_4461 Ephrin_B_EPHB2_KALRN_1act_dendritic_spine red _h_4594_2 blue Erk2_1O_1O_1act grey red _h_3745 blue NPC_RanGAP1_SUMO1_RanBP2_Ubc9 and Ran_GTP_Exportin_1_HDAC4_cytoplasm red _h_3747 blue RET9 blue _h_3746 TCF3_beta_catenin_TERT_BRG1_1act_nucleus blue _h_3740 ( not (DHT_plasma_membrane or testosterone_plasma_membrane)) blue _h_3743 (AR_T_DHT_nucleus and ( not RXRs_9cRA)) red _h_4594_1 blue Erk2_1O_1O_1act red red _h_6229_6 blue 14_3_3_E_cytoplasm and KPNA1 red _h_6229_4 blue KPNA1 and YWHAG_cytoplasm _h_6229_3 blue YWHAS_cytoplasm and p27Kip1_1O red _h_6229_1 blue (KPNA1 and YWHAQ_cytoplasm) grey grey red _h_4594_4 blue Erk2_1O_1O_1act red grey red grey blue _h_1089 Arf6_GTP_1act grey red grey _h_1687 blue RAC1_GTP_1act_plasma_membrane blue _h_2959 HIF2A_ARNT_nucleus_v2 red _h_4663 blue DSCR1L1 red red blue _h_3777 E2F1_DP_nucleus_v4 grey grey blue _h_6221_4 CAMKK2_1act_cytoplasm or LKB1_MO25_STRADA_STRADB_cytoplasm_v2 grey grey red grey blue _h_456_3 Lethal_Factor_cytoplasm grey grey red grey blue _h_4164 Akt1_1O_1O_1act_plasma_membrane blue _h_4165 Myb_nucleus blue _h_4166 PKR_1act _h_4160 blue TRKB_1N_integral_to_membrane blue _h_4161 RAF1_1act grey _h_4590 blue CDC42_GTP_1act_cell_cell_junction and IQGAP1 blue _h_2953 (((JUN_FOSNFAT1_c_4_1act_nucleus_c_Jun_2O_NFAT1_1O_7O_2s_1act_nucleus_FOS_1O_1O or JUN_FOSNFAT1_c_4_1act_nucleus_c_Jun_2O_NFAT4_1act_nucleus_FOS_1O_1O) or JUN_FOSNFAT1_c_4_1act_nucleus_c_Jun_2O_NFATc_1act_nucleus_FOS_1O_1O) or STAT4__dimer__1act_nucleus_v2) grey blue _h_4168 Fra1_JUN_1act_nucleus _h_4169 blue (CDC42_GDP_1ina_dendritic_spine and Ephrin_B_EPHB2_Intersectin_N_WASP_1act_dendritic_spine) red blue _h_142 SHP1_1act_2O grey grey _h_2951 blue betaglycan__dimer__integral_to_membrane_v1 grey grey red red _h_2950 blue p14ARF _h_3263_47 blue FGFR1c_FGF1_1act grey grey red grey grey grey grey grey _h_455_6 blue RAF1_14_3_3_1act_plasma_membrane_RAF1_1O_3O_YWHAS red grey blue _h_3469 TCPTP_p45_nucleus _h_2392_4 blue KSR_1act_plasma_membrane or PP2A_1act_v1 or RAS_family_GTP_1act_plasma_membrane_H_RAS_isoform_1_GTP_v1 or RAS_family_GTP_1act_plasma_membrane_N_RAS_GTP_v1 _h_4847 blue Cone_pigment__S_M_L_ _h_2392_6 blue KSR_1act_plasma_membrane or PP2A_1act_v1 or RAS_family_GTP_1act_plasma_membrane_H_RAS_isoform_1_GTP_v1 or RAS_family_GTP_1act_plasma_membrane_N_RAS_GTP_v1 _h_5272_1 blue Src_PTPD1 blue _h_2838 (AR_T_DHT_nucleus and ( not FOXO1)) _h_2392_1 blue KSR_1act_plasma_membrane or PP2A_1act_v1 or RAS_family_GTP_1act_plasma_membrane_H_RAS_isoform_1_GTP_v1 or RAS_family_GTP_1act_plasma_membrane_N_RAS_GTP_v1 _h_2392_2 blue KSR_1act_plasma_membrane or PP2A_1act_v1 or RAS_family_GTP_1act_plasma_membrane_H_RAS_isoform_1_GTP_v1 or RAS_family_GTP_1act_plasma_membrane_N_RAS_GTP_v1 grey _h_2834 blue p300_nucleus blue _h_2835 Aurora_A or Chromosomal_passenger_complex_1act_chromosome blue _h_2836 Src_1O_1act_cell_cell_junction grey blue _h_2830 JAK1_1act_2O _h_2831 blue Vitronectin_extracellular_matrix blue _h_2832 ( not IL27_IL27R_JAK2_TYK2_1act) _h_869 blue CRK_DOCK1 red _h_6266_2 blue FOS_nucleus red _h_6266_4 blue FOS_nucleus red red red blue _h_4739 ( not STX1A_1act) red grey red _h_865 blue (IQGAP1_cytoplasm and ( not RAC1_CDC42_GTP_IQGAP1_cell_cell_junction)) red blue _h_4840 (E2_ERA__dimer__1act_nucleus and ( not E2_ERA__dimer__REA_1act_nucleus)) grey _h_5703_1 blue PDGF_BB_PDGFRB__dimer__1act_integral_to_membrane_v1 red blue _h_5446 SCF_KIT_1act red red red red red grey grey red grey blue _h_4573 JUN_FOS_GATA2_1act_nucleus blue _h_4344 JUNB__dimer__p300_1act_nucleus blue _h_4571 JUN_ATF2_1act_nucleus _h_4570 blue alphav_beta3_Integrin and (Type_IV_Collagen or Type_I_Collagen) red _h_4576 blue Plexin_D1_Nrp1_integral_to_membrane blue _h_4575 PER1_2___CRY1_2_nucleus blue _h_4345 TCPTP_p45_nucleus blue _h_4579 HIF1A_ARNT_nucleus red blue _h_4686 HGS_1act red grey grey red blue _h_4620 TGFB_TGFBR2_TGFBR1_1act_integral_to_membrane grey _h_4341 blue Ephrin_A5_integral_to_membrane blue _h_4343_1 GMCSF_GMR_alpha_CSF2RB_JAK2__dodecamer__1act_integral_to_membrane_v1 blue _h_3237 Erk2_1O_1O_1act or SCP1 or SCP2 red grey red red red grey red red _h_1052 blue alpha4_beta1_Integrin_integral_to_membrane_v1 grey blue _h_961 Plasmin_1act grey blue _h_6007 p53__tetramer__nucleus_v2 grey blue _h_1050 (EPO_EPOR__dimer__JAK2 or EPO_EPOR__dimer__LYN) _h_5691_3 blue RB1_E2F1_3_DP_nucleus_v3_DP1_E2F3_RB1 _h_5691_2 blue RB1_E2F1_3_DP_nucleus_v3_DP1_E2F1_RB1 _h_5691_1 blue RB1_E2F1_3_DP_nucleus_v3_DP1_RB1_E2F2 blue _h_108 CBL_Ubc4_5_family_endosome or CBL_b_1act_endosome _h_107 blue SMAD2_SMAD2_SMAD4_1act_nucleus_v1 grey grey blue _h_103 VEGFR2__dimer__VEGFA__dimer__CBL_1act_integral_to_membrane_v1 grey _h_101 blue RBPJ_NICD_1act_nucleus blue _h_100 CBL_1act_1O_plasma_membrane blue _h_6003 MSK1_1act or MSK2_1act grey blue _h_1054 ETA_receptor_Endothelin_1_integral_to_membrane red grey grey grey blue _h_1036_37 Arf6_GTP_1act or Arf6_GTP_1act_plasma_membrane red grey grey red red blue _h_1036_59 Arf6_GTP_1act or Arf6_GTP_1act_plasma_membrane blue _h_1059 PAK1_1O_1O_1act grey red grey red _h_1875 blue Insulin_Receptor_Insulin_v2 and PDK1_cytoplasm red blue _h_1876 ((STAT5A_B__dimer__1act_nucleus or STAT5A__dimer__active_1act_nucleus_v2) or STAT5B__dimer__1act_nucleus) blue _h_89 (BMP2_4_BMPR2_BMPR1A_1B_RGM_1act_integral_to_membrane or PPM1A) grey blue _h_1873 Fra1_JUN_1act_nucleus blue _h_1872 Insulin_Receptor_Insulin_SHC_GRB2_Sos1 and not Insulin_Receptor_Insulin_SHC_GRB10 blue _h_85 PI3K_1act_cell_cell_junction_v2 blue _h_84 SMAD3_SMAD4_TFE3_1act_nucleus _h_87 blue GLI2_cytoplasm blue _h_86 PKC_theta_1act_plasma_membrane blue _h_1879 (Pit_1 and ( not cortisol_GR_alpha__monomer__nucleus)) red blue _h_83 Intersectin_1act_endosome or LRIG1 _h_82 blue cortical_actin_cytoskeleton red _h_4057 blue CDC42_GTP_1act and CK1_alpha red grey red red red red blue _h_1754 RAS_family_GTP_PI3K_1act_plasma_membrane_PIK3R1_H_RAS_isoform_1_p110_alpha_GTP_v1 or RAS_family_GTP_PI3K_1act_plasma_membrane_PIK3R1_N_RAS_p110_alpha_GTP_v1 or Src_1act red grey red red _h_5029 blue FZD9_integral_to_membrane and LRP6_integral_to_membrane grey grey _h_5023 blue GRIN2B and RELN_LRP8_DAB1_Fyn red grey blue _h_5027 APAF_1_Caspase_9_1act or Caspase_8__4_units__1act _h_5024 blue (ErbB3_integral_to_membrane and NRG1_extracellular_region) grey blue _h_5479_2 CK1_epsilon_cytoplasm grey blue _h_1919 DEP1_1act or PTP1B red grey blue _h_1910 p53__tetramer__nucleus_v2 blue _h_1911 (FOXO3A_nucleus and ( not MYC_Max_nucleus_v4)) grey _h_2014 blue PI3K_plasma_membrane and SHC_cytoplasm red blue _h_4051 PI_3_4_5_P3_plasma_membrane red grey red red red grey red blue _h_4652 not TRAILR4__trimer__integral_to_membrane and (TRAIL_TRAILR1_FADD_integral_to_membrane or TRAIL_TRAILR2_FADD_integral_to_membrane) blue _h_3943 p38_alpha_1O_1O_1act_v2 or p38_beta_1O_1O_1act red _h_4651 blue SMAD5_2O_1act_cytoplasm grey _h_5277 blue BMP2_4_BMPR2_BMPR1A_1B_RGM_1act_integral_to_membrane and GADD34_PP1CA grey grey grey _h_921_2 blue KSR_1act_plasma_membrane or RAS_family_GTP_1act_plasma_membrane_H_RAS_isoform_1_GTP_v1 or RAS_family_GTP_1act_plasma_membrane_N_RAS_GTP_v1 grey red grey red red red grey grey grey grey grey _h_4658 blue ((GTP_v1 and TP_beta_Gq_family_GDP_G_beta5_gamma2) and ( not TXA2_TP_beta_1ina_integral_to_membrane)) blue _h_2249 CEBPA_nucleus or CEBPB_nucleus or CEBPD_nucleus or Myb_1act_nucleus or SPI1_nucleus grey _h_2247 blue GRB2_SHC _h_2246 blue alpha9_beta1_Integrin_integral_to_membrane _h_2245 blue BAMBI and BMP2_4__homodimer__extracellular_region and BMPR2__homodimer__1act_integral_to_membrane and FETUA and RGM_family blue _h_2244 FAK_6O_1act _h_2243 blue T_DHT_AR_PELP1_Src_plasma_membrane _h_2241 blue alphav_beta3_Integrin _h_2240 blue alpha2_beta1_Integrin_integral_to_membrane grey red _h_2555 blue TIP49B_nucleus grey red red blue _h_4378 (((JUN_FOSNFAT1_c_4_1act_nucleus_c_Jun_2O_NFAT1_1O_7O_2s_1act_nucleus_FOS_1O_1O or JUN_FOSNFAT1_c_4_1act_nucleus_c_Jun_2O_NFAT4_1act_nucleus_FOS_1O_1O) or JUN_FOSNFAT1_c_4_1act_nucleus_c_Jun_2O_NFATc_1act_nucleus_FOS_1O_1O) and ( not ((NFAT1_c_4_ICER1_1act_nucleus_ICER1_NFAT1_1O_7O_2s_1act_nucleus or NFAT1_c_4_ICER1_1act_nucleus_ICER1_NFAT4_1act_nucleus) or NFAT1_c_4_ICER1_1act_nucleus_ICER1_NFATc_1act_nucleus))) blue _h_1207 CD40_CD40L__trimer__TRAF6_PI3K_Class_I_family_CBL_b_integral_to_membrane_PI3K_CD40_CBL_b_TRAF6_CD40LG or CD40_CD40L__trimer__TRAF6_PI3K_Class_I_family_CBL_b_integral_to_membrane_PI3K_gamma_p84_CD40_CBL_b_TRAF6_CD40LG red blue _h_6005 IL23_IL23R_JAK2_TYK2_1act_integral_to_membrane grey grey red blue _h_4373 MEKK2_1O_1act blue _h_1274 HIF2A_ARNT_nucleus_v3 blue _h_4375 not IL4_IL4R_JAK1_IL2R_gamma_JAK3_SHP1_1act_integral_to_membrane and (IL4_IL4R_JAK1_IL13RA1_JAK2_1act_integral_to_membrane or IL4_IL4R_JAK1_IL2R_gamma_JAK3_1act_integral_to_membrane) _h_4374 blue MHF2 blue _h_4377 TCF4E_beta_catenin_1act_nucleus red grey grey grey red grey _h_1748 blue PLGF1__dimer__extracellular_region blue _h_5708 MYC_Max_nucleus_v2 blue _h_1036_51 Arf6_GTP_1act or Arf6_GTP_1act_plasma_membrane _h_4693_3 blue p53_mitochondrion blue _h_2798 (p53_nucleus and ( not cortisol_GR_alpha__dimer__nucleus_v1)) grey blue _h_5706 DOCK7_1act_1O grey blue _h_2790 MKK3_1O_1O_1act _h_2793 blue NGF__dimer__extracellular_region _h_2067 blue Myb_nucleus _h_2066 blue AR_T_DHT_nucleus _h_2797 blue Smad7 and YAP65 grey blue _h_1268 not glutathione and (TNF_alpha_TNFR1A_FAN or TNF_alpha_TNFR1A_TRADD_MADD_cIAP2_RIP_TRAF2_RAIDD) _h_4082 blue HDAC1_nucleus and HDAC2_nucleus and RBBP4_nucleus blue _h_4081 PIP5K1A_1act_plasma_membrane_v2 or PIP5K1B_1act_plasma_membrane or PIP5K1C_1act_plasma_membrane _h_4080 blue ACAP1_cytoplasm and Arf6_GTP_1act and clathrin_heavy_chain_cytoplasm grey _h_4086 blue PARP2 blue _h_4084 PKC__alpha_beta_epsilon_zeta__1act_cytoplasm blue _h_1260 ERK1_2_ELK1_1act_nucleus red blue _h_4089 (( not KAP1) and ((E2F1_3_DP_nucleus_DP1_E2F1 or E2F1_3_DP_nucleus_DP1_E2F2) or E2F1_3_DP_nucleus_DP1_E2F3)) red grey blue _h_1265 ITCH_1act blue _h_1266 PLK1_1O_1act grey grey red red _h_5700 blue alphaM_beta2_Integrin_uPA red red grey blue _h_4716 HRAS_GTP_1act_plasma_membrane blue _h_2944_34 not E_cadherin_cytoplasm and (MAPK_14 or p120ctn) _h_6229_2 blue (KPNA1 and YWHAZ_cytoplasm) grey blue _h_6369 FOXM1C_2O_1act_nucleus red grey blue _h_2799_2 MKP1_1act_nucleus _h_3861 blue Vinculin grey red _h_4715 blue Gi_family and S1P_extracellular_region red grey _h_5802_3 blue CaMK and IFN_gamma_IFN_gammaR_JAK1_JAK1_JAK2_JAK2_1act _h_5151 blue CAMKIIB or Ca2__v1 or DAB2IP_1act or GAP1M_1act or GAP1_IP4BP_1act_plasma_membrane or Neurofibromin_1act_cytoplasm or PI_3_4_5_P3_plasma_membrane or PI_4_5_P2_plasma_membrane or RASAL_1act or RasGAP_1act or SYNGAP1_1act grey red grey grey grey grey blue _h_3412 PKA_1act grey grey red _h_3867 blue PKC_zeta and ceramide _h_1210_2 blue p300_nucleus grey _h_3688 blue nonstructural_protein_3A_precursor blue _h_3689 not cortisol_GR_alpha__monomer__nucleus blue _h_5646 Syk_1O_1act or alphav_beta3_Integrin_Osteopontin_Src blue _h_3680 LNX red grey blue _h_3683 Myb_nucleus blue _h_3687 Akt1_1act_cytoplasm or CaM_Ca2_ or PRKACA grey grey red grey blue _h_2944_31 not E_cadherin_cytoplasm and (MAPK_14 or p120ctn) red grey grey grey red red _h_3532 blue DAX_1 blue _h_3533 MEK1_2O_1act_cytoplasm blue _h_3530 RHOA_GTP_1act_plasma_membrane _h_3531 blue (GTP_v1 and p190RHOGEF_1act_1O_focal_adhesion) grey _h_3537 blue RICTOR _h_3534 blue SIRT2_cytoplasm grey blue _h_3539 RB1_nucleus or RBP2 grey grey red grey red blue _h_6161 B_cell_antigen_BCR_complex_Btk_LYN_SYK_BLNK_PLCgamma2 grey blue _h_6259 MSP blue _h_5569 PKA_Family_active_1act red _h_5566 blue GRB2_GAB2_plasma_membrane grey _h_5564 blue TCR_CD3_MHC_II_CD4_1act_integral_to_membrane _h_5563 blue IGF1 and IRS1 and (Fibronectin_v2 or alphav_beta3_Integrin) blue _h_5562 (STAT1__dimer__1act_v1 or STAT3__dimer___1act) blue _h_5561 CaM_Ca2__Calcineurin_A_alpha_beta_B1_1act_v2 grey grey red red red _h_4711 blue TRF1 blue _h_2944_33 not E_cadherin_cytoplasm and (MAPK_14 or p120ctn) _h_3581_3 blue JUNB and NFAT1_1O_7O_2s_1act_nucleus _h_4158_4 blue p53_BCL2_subfamily_mitochondrion_BCL_X_p53 _h_4158_2 blue p53_BCL2_subfamily_mitochondrion_BCL2A1_p53 _h_4158_3 blue PUMA _h_4158_1 blue p53_BCL2_subfamily_mitochondrion_MCL1_p53 red red blue _h_845 GSK3beta _h_795_2 blue DNMT1 grey red red grey red grey red grey grey _h_352 blue ErbB4_CYT2_integral_to_membrane red grey blue _h_351 GSK3beta_1act red red red grey grey _h_358 blue SIRT7_nucleolus blue _h_359 (Erk1_1O_1act_1O_nucleus or Erk2_1O_1O_1act_nucleus) grey red grey red _h_1889_2 blue RXR_alpha and VDR_VDR_DNA and Vit_D3 _h_1889_1 blue ((RXR_alpha and Rar_gamma1) and VDR_VDR_DNA) red blue _h_247 E2F1_DP_nucleus_v4 blue _h_248 (( not GRAIL) and ((JUN_FOSNFAT1_c_4_1act_nucleus_c_Jun_2O_NFAT1_1O_7O_2s_1act_nucleus_FOS_1O_1O or JUN_FOSNFAT1_c_4_1act_nucleus_c_Jun_2O_NFAT4_1act_nucleus_FOS_1O_1O) or JUN_FOSNFAT1_c_4_1act_nucleus_c_Jun_2O_NFATc_1act_nucleus_FOS_1O_1O)) blue _h_2032_1 BDNF__dimer__TRKB_1act_integral_to_membrane_v1 or NGF__dimer__TRKA_1act_endosome red blue _h_6406 ((JUN_FOSNFAT1_c_4_1act_nucleus_c_Jun_2O_NFAT1_1O_7O_2s_1act_nucleus_FOS_1O_1O or JUN_FOSNFAT1_c_4_1act_nucleus_c_Jun_2O_NFAT4_1act_nucleus_FOS_1O_1O) or JUN_FOSNFAT1_c_4_1act_nucleus_c_Jun_2O_NFATc_1act_nucleus_FOS_1O_1O) grey red grey red blue _h_3895_6 Ran_GTP_Exportin_1 red red grey grey red grey grey blue _h_2992 ( not Smad3_MYC_1act) grey grey blue _h_4964 PIP3 blue _h_4965 Fibronectin_alpha4_beta1_Integrin_cell_leading_edge or LRP_1act or alpha4_beta1_Integrin_VCAM1_integral_to_membrane _h_4966 blue Aurora_A_RasGAP blue _h_4967 JUN_FOS_1act_nucleus_v4 red blue _h_4961 (JUN_JUN_FOS_p300_1act_nucleus_FOS_p300_JUN_2O_2O or JUN_JUN_FOS_p300_1act_nucleus_JUN_p300_JUN_2O_2O) _h_4962 blue Slit_Robo_c_Abl_Cables_1act _h_6362 blue Syndecan_1 blue _h_5764 p38_alpha_1O_1O_1act_v2 red red _h_1540 blue Nrp1 and VEGFA_homodimer_extracellular_region_v1 red grey red blue _h_2944_68 not E_cadherin_cytoplasm and (MAPK_14 or p120ctn) red blue _h_4290_1 LPA_LPA4 _h_2917_2 blue DVL2_1act grey _h_6363 blue HRAS_GTP_1act_v1 blue _h_5767 ERK1_2_ELK1_1act_nucleus blue _h_3459 (p38_alpha_1O_1O_1act_v2 or p38_beta_1O_1O_1act) blue _h_4918_2 Lethal_Factor_cytoplasm red red grey red red grey blue _h_4918_1 Lethal_Factor_cytoplasm red grey blue _h_6221_3 CAMKK2_1act_cytoplasm or LKB1_MO25_STRADA_STRADB_cytoplasm_v2 grey _h_5766 blue BRCA1 and FANCD2_FANCI_chromatin grey red blue _h_2944_61 not E_cadherin_cytoplasm and (MAPK_14 or p120ctn) grey blue _h_6221_1 CAMKK2_1act_cytoplasm or LKB1_MO25_STRADA_STRADB_cytoplasm_v2 blue _h_6249 PI3K_1act_cell_cell_junction_v2 or Src_1O_1act_cell_cell_junction grey blue _h_2944_66 not E_cadherin_cytoplasm and (MAPK_14 or p120ctn) grey grey _h_1750 blue MAGI_3 grey grey grey blue _h_2944_65 not E_cadherin_cytoplasm and (MAPK_14 or p120ctn) grey blue _h_644 p38alpha_beta_MAPKAPK2_1act_MAPKAPK2_4O_1O_p38_alpha_1O_1O_1act_v2 or p38alpha_beta_MAPKAPK2_1act_MAPKAPK2_4O_1O_p38_beta_1O_1O_1act red grey _h_6248 blue MADD and RAIDD and RIP_cytoplasm and TNFR1A_BAG4_TNF_alpha_v2 and TRAF2_cytoplasm and cIAP2_cytoplasm blue _h_2040 GATA1_nucleus or Myb_nucleus red grey _h_965 blue YWHAZ grey red red grey grey _h_3392_2 blue Nephrin_NEPH1_podocin_membrane_raft_v1 _h_3392_1 blue NCK1_cytoplasm blue _h_643 CBL_1act_plasma_membrane red grey red grey grey grey grey grey _h_4162 blue JUN_FOS_1act_nucleus_v4 red blue _h_4163 Aurora_B red grey blue _h_649 TCF4_beta_catenin_JUN_DVL3_1act_nucleus red red blue _h_5051_64 (RAS_family_GTP_1act_plasma_membrane_H_RAS_isoform_1_GTP_v1 or RAS_family_GTP_1act_plasma_membrane_N_RAS_GTP_v1) grey grey red red _h_2474 blue RasGAP blue _h_3557 Akt1_1O_1O_1act_plasma_membrane grey _h_2470 blue Sema3e_Plexin_D1_integral_to_membrane grey blue _h_2472 JNK2_1O_1O_1act or Jnk1_1O_1act_1O blue _h_2473 not I_kappa_B_alpha_1act_cytoplasm blue _h_3697 ILK_1act_1p _h_2478 blue GTP_v1 and NME1_1act_basolateral_plasma_membrane red red red blue _h_3694 CEBPB_nucleus or Myb_nucleus grey grey red red _h_1078 blue B_cell_antigen_BCR_complex_LYN_SYK_BLNK and PLCgamma2_cytoplasm and not (IBtk or SAB) red red _h_1074 blue GATA1_nucleus grey blue _h_1076 DNM1 blue _h_1071 DNA_PKcs_1act or mTORC2 red _h_1073 blue ET1_extracellular_region blue _h_1072 IL6_IL6RA_gp130__dimer__JAK1_JAK1_LMO4_1act_integral_to_membrane_v2 red grey red red grey red grey blue _h_2997 Vitronectin or alphav_beta3_Integrin _h_5089 blue Jak2 grey red red red red grey grey grey grey red blue _h_1643 TAp63g__tetramer__1act_nucleus_v2 _h_388_2 blue testosterone_plasma_membrane red blue _h_2996 hZIMP10 grey blue _h_1641 (JUN_FOS_NFAT1_1act_nucleus and ( not NFAT1_FOXP3)) red blue _h_5758_2 PI_3_4_5_P3_plasma_membrane grey grey red blue _h_5889 TCR_CD3_MHC_II_CD4_LCK_1act_integral_to_membrane or TCR_CD3_MHC_I_CD8_LCK_1act_integral_to_membrane red blue _h_5082 E2F3_DP_nucleus _h_2169 blue TRAILR4__trimer__integral_to_membrane grey red grey grey blue _h_1032_1 PI_3_4_5_P3_plasma_membrane grey grey blue _h_1648 MCM7 grey red red grey grey grey grey blue _h_4148 (((JUN_FOSNFAT1_c_4_1act_nucleus_c_Jun_2O_NFAT1_1O_7O_2s_1act_nucleus_FOS_1O_1O or JUN_FOSNFAT1_c_4_1act_nucleus_c_Jun_2O_NFAT4_1act_nucleus_FOS_1O_1O) or JUN_FOSNFAT1_c_4_1act_nucleus_c_Jun_2O_NFATc_1act_nucleus_FOS_1O_1O) or T_bet) grey grey _h_4175 blue IL6_IL6RA_gp130__dimer__JAK1_JAK1_LMO4_1act_integral_to_membrane_v2 and PIAS3_MITF _h_4144 blue I_kappa_B_alpha_HDAC3_cytoplasm and (TNF_alpha_TNFR1A or beta_TrCP1_SCF_ubiquitin_ligase_complex) blue _h_4145 Elf1_1act_nucleus blue _h_4142 TIP49A or TIP49B red blue _h_4140 dNp63a__tetramer__nucleus_v2 _h_4141 blue FRS2_family_SHP2_1act red grey blue _h_2380_1 Lethal_Factor_cytoplasm grey blue _h_2380_3 Lethal_Factor_cytoplasm blue _h_2380_2 Lethal_Factor_cytoplasm grey grey grey grey grey _h_2812 blue ErbB2_integral_to_membrane and NRG1_extracellular_region _h_2813 blue Thrombospondin_extracellular_region blue _h_2810 PKC_zeta_1act_1p_plasma_membrane blue _h_4174 Aquaporin_5_Golgi_apparatus or SEC6_SEC8_cell_cell_junction or Syntaxin_4_cell_cell_junction _h_2518 blue STRAP_1O_nucleus blue _h_2818 JUN_2O_nucleus or p53__tetramer__nucleus_v2 _h_2819 blue Tie2_Ang1_1act grey blue _h_3386 SCF_KIT_1act red grey grey grey blue _h_4819 PKC_1act blue _h_3380 SMAD2_SMAD2_SMAD4_FOXH1_NKX2_5_1act_nucleus grey _h_5272_2 blue Src_PTPD1 _h_2642_2 blue beta5_Integrin_v1 blue _h_3383 LAT_GRAP2_SLP76_VAV1_NCK1_1act_integral_to_membrane blue _h_2899 p38_alpha_1O_1O_1act_v2 grey blue _h_2512 AMSH_1act_endosome or USP8_1act grey grey grey grey red _h_3520 blue PIM1_1act_nucleus grey red blue _h_2799_1 MKP1_1act_nucleus _h_2736 blue Furin_or_Furin_like_Endopeptidase _h_3389 blue alpha3_beta1_Integrin_integral_to_membrane _h_2392_3 blue KSR_1act_plasma_membrane or PP2A_1act_v1 or RAS_family_GTP_1act_plasma_membrane_H_RAS_isoform_1_GTP_v1 or RAS_family_GTP_1act_plasma_membrane_N_RAS_GTP_v1 grey _h_6475 blue NOTCH1_precursor _h_228_1 blue ETA_receptor_Endothelin_1_Gq_GTP_1act_integral_to_membrane grey red blue _h_4555 (Nephrin_NEPH1_podocin_membrane_raft_v2 or netrin_1_UNC5B_1act_integral_to_membrane) grey blue _h_4557 TAp73a__tetramer__nucleus_v3 blue _h_4556 (p53__tetramer__nucleus_v2 and ( not HDAC2_nucleus)) grey blue _h_4550 (FOXA2_nucleus_v1 or FOXA2_nucleus_v2) grey grey grey grey red blue _h_2731 Insulin_Receptor_Insulin_v2 or PDGF_BB_PDGFRB__dimer__1act_v1 grey grey grey grey grey red red grey grey grey red _h_2833 blue Vitronectin_extracellular_region blue _h_4170 Digestive_enzymes_endosome blue _h_807_44 FASLG_FAS__trimer__Src_Syk_1act_integral_to_membrane or TRAIL__trimer__extracellular_region red _h_5921 blue SMAD3_SMAD4_1act_nucleus grey _h_5647_2 blue E2F1_3_DP_DP1_E2F3 and RB1_2N_nucleus red _h_5647_1 blue E2F1_3_DP_DP1_E2F1 and RB1_nucleus red grey blue _h_1154_1 CD40_CD40L__trimer__TRAF3__trimer__integral_to_membrane _h_3995_4 blue EPHA1_integral_to_membrane grey _h_3995_2 blue Ephrin_A1_integral_to_membrane _h_3995_3 blue EPHA2_integral_to_membrane blue _h_3213 ABCC1 blue _h_160 DAG_v2 _h_163 blue (GTP_v1 and IL8_CXCR1_1act_integral_to_membrane_v2) blue _h_162 EPO_EPOR__dimer__JAK2 blue _h_165 HIF1A_ARNT_nucleus grey blue _h_167 RBPJ_NICD_1act_nucleus grey red _h_4209 blue SHB grey grey blue _h_5594 cortisol_GR_alpha__dimer__nucleus_v4 _h_4208 blue TSC1_TSC2_1act or TSC1_TSC2_v2 grey red red grey grey blue _h_5795 (CBF and ( not p53__tetramer__nucleus_v2)) _h_5796 blue CHRNA1_integral_to_membrane red grey _h_5791 blue DVL3_nucleus and TCF4_beta_catenin_1act_nucleus red blue _h_5793 dNp63g__tetramer__nucleus red grey _h_5798 blue Antigen_IgE_Fc_epsilon_R1 _h_5799 blue B7_family_CD28_1act_integral_to_membrane_v2 and TCR_CD3_MHC_I_CD8_1act_integral_to_membrane grey grey _h_5334 blue alphaM_beta2_Integrin grey grey grey grey red grey grey blue _h_1899 Myb_nucleus blue _h_1898 PDK1_1O _h_1896 blue Thrombin grey _h_1894 blue CBL and PDGF_BB_PDGFRB__dimer__1act_integral_to_membrane_v1 grey grey grey grey _h_4202 blue PDGFRB_integral_to_membrane and PDGF_BB_1act_extracellular_region blue _h_3028 HIF1A_ARNT_nucleus red _h_3024 blue MKLP2_microtubule and PLK1_1O_1act blue _h_3025 TAp73a__tetramer__nucleus_v4 _h_3027 blue PIAS1 and STAT1__dimer__1act_nucleus_v1 and STAT1__dimer__1act_nucleus_v2 _h_3020 blue JUNB_nucleus blue _h_3021 FGFR1b_FGF10_plasma_membrane or FGFR1b_FGF1_plasma_membrane or FGFR1b_FGF2_plasma_membrane or FGFR1b_FGF3_plasma_membrane or FGFR1c_FGF1_plasma_membrane or FGFR1c_FGF2_plasma_membrane or FGFR1c_FGF4_plasma_membrane or FGFR1c_FGF5_plasma_membrane or FGFR1c_FGF6_plasma_membrane or p120ctn _h_3022 blue PI3K_cytoplasm grey grey _h_31 blue alpha6_beta4_Integrin red blue _h_4207 (p53__tetramer__nucleus_v2 and ( not TAp63b)) _h_5271 blue IL1_alpha_IL1R1_IL1RAP_MYD88_IRAK4_IRAK_TOLLIP_1act_integral_to_membrane grey red grey red grey red blue _h_6343 HIF1A_ARNT_nucleus grey grey blue _h_3049 NF_kappa_B_RelA_1act_nucleus_v1 and not I_kappa_B_alpha_1act_nucleus grey grey grey red red _h_1131 blue (PI3K_Class2_beta_polypeptide_plasma_membrane and SCF_KIT_1act) red blue _h_5977_1 IL6_IL6RA_gp130__dimer__JAK1_JAK1_LMO4_Hck_1act_integral_to_membrane red blue _h_1427 ARF6_GDP_1ina_plasma_membrane_v2 grey grey red _h_1425 blue GTP_v1 and (BDNF__dimer__TRKB_1act_endosome_v1 or FRS2_family_SHP2_CRK_family_C3G_GAB2_1act_GAB2_FRS2_family_active_1act_Crk_cytoplasm_SHP2_1O_cytoplasm_C3G_1O or FRS2_family_SHP2_CRK_family_C3G_GAB2_1act_GAB2_FRS2_family_active_1act_SHP2_1O_cytoplasm_CRKL_cytoplasm_C3G_1O or KIDINS220_CRKL_C3G_1act) grey _h_33 blue p130Cas and paxillin and not Gi_family_GTP_RGS1_1act_cytoplasm and (Fyn_1O_1act or GNB1_GNG2_1act_cytoplasm or LYN_1act_1O or Lck_1O_1act or SDF1_CXCR4_JAK2_1act_integral_to_membrane or Src_1act_1O) grey blue _h_5661 JUN_ATF2_1act_nucleus grey grey blue _h_830_4 PIN1_1act or PP2A_1act_v1 red blue _h_1428 IL2_IL2R_1act_integral_to_membrane blue _h_904 TXA2_TXA2_R_family_1act_integral_to_membrane grey grey blue _h_5501 cortisol red grey red red red blue _h_1832 PI3K_1act_plasma_membrane_v2 or RET51_GFRalpha1_GDNF_v1 red blue _h_4464 RHOA_GTP_1act or RHOA_GTP_1act_cell_cell_junction or RhoA_1act or RhoC_1act red grey blue _h_5500 PKA_1act or TGFB1_TGF_beta_receptor_Type_II_1act grey grey blue _h_3874 dNp63a__tetramer__nucleus_v2 blue _h_5663 GC1_GCAP_Family_1act_v1 or GC1_GCAP_Family_1act_v2 or GC2_GCAP_Family_1act grey _h_2260 blue CD40LG blue _h_2263 Mn2_ or PI_3_4_5_P3 blue _h_2262 p53__tetramer__nucleus_v2 _h_2265 blue CBP_nucleus _h_2267 blue ILK and betaPIX blue _h_2266 E4ICDs_1act_5O_cytoplasm and not WWOX_E4ICDs_cytoplasm blue _h_1798 not XIAP and (APAF_1_Caspase_9_1act or Caspase_10_1act or Caspase_2_1act or Caspase_8_1act or Granzyme_B_cytoplasm) grey grey red red _h_4314 blue ((FZD8_integral_to_membrane and SOST) and WNT1_extracellular_region) red _h_1791 blue Src_1 _h_4319 blue YWHAQ _h_4318 blue CHD7 and Nemo_like_kinase_1p_1act red blue _h_2434_50 ((EGFR_EGFR_1act_integral_to_membrane_v1 or EGFR_EGFR_EGF_EGF_GRB2_GAB1_1act_integral_to_membrane_v1) and ( not (EGFR_EGFR_1ina_integral_to_membrane or EGFR_EGFR_EGF_EGF_GRB2_GAB1_1ina_integral_to_membrane))) blue _h_1796 TCF1E_beta_catenin_1act_nucleus grey blue _h_3428 (( not IL6_IL6RA_gp130__dimer__JAK1_JAK1_LMO4_SOCS3_1act_integral_to_membrane) and (IL6_IL6RA_gp130__dimer__JAK1_JAK1_LMO4_1act_integral_to_membrane_v2 or nPKC_delta_1O_1act)) grey _h_3538_2 blue NKD2_1m_plasma_membrane grey grey red grey grey grey grey blue _h_2045 FOXA1_nucleus grey red blue _h_2046 HIF2A_ARNT_nucleus_v3 red red red _h_2049 blue BRCA1_BARD1 and PCNA grey red red red red _h_4577 blue (EGFR_integral_to_membrane and EGF_extracellular_region) grey grey grey grey blue _h_1359 TGF_beta2 grey red _h_3995_1 blue EPHA4_integral_to_membrane grey red grey blue _h_3770_6 (((((((ErbB2_ErbB3_neuregulin_1_beta_1act_integral_to_membrane_v3 or ErbB4_ErbB4_HBEGF_HBEGF_1act_integral_to_membrane) or ErbB4_ErbB4_neuregulin_1_beta_neuregulin_1_beta_1act_integral_to_membrane_v2) or ErbB4_ErbB4_neuregulin_2_beta_neuregulin_2_beta_1act_integral_to_membrane) or ErbB4_JM_B_ErbB4_JM_B_neuregulin_1_beta_neuregulin_1_beta_1act_integral_to_membrane_v1) or GNB1_GNG2_1act_cytoplasm) or Nephrin_NEPH1_podocin_CD2AP_membrane_raft) or Nephrin_NEPH1_podocin_membrane_raft_v1) blue _h_3770_5 (((((((ErbB2_ErbB3_neuregulin_1_beta_1act_integral_to_membrane_v3 or ErbB4_ErbB4_HBEGF_HBEGF_1act_integral_to_membrane) or ErbB4_ErbB4_neuregulin_1_beta_neuregulin_1_beta_1act_integral_to_membrane_v2) or ErbB4_ErbB4_neuregulin_2_beta_neuregulin_2_beta_1act_integral_to_membrane) or ErbB4_JM_B_ErbB4_JM_B_neuregulin_1_beta_neuregulin_1_beta_1act_integral_to_membrane_v1) or GNB1_GNG2_1act_cytoplasm) or Nephrin_NEPH1_podocin_CD2AP_membrane_raft) or Nephrin_NEPH1_podocin_membrane_raft_v1) grey blue _h_3770_3 (((((((ErbB2_ErbB3_neuregulin_1_beta_1act_integral_to_membrane_v3 or ErbB4_ErbB4_HBEGF_HBEGF_1act_integral_to_membrane) or ErbB4_ErbB4_neuregulin_1_beta_neuregulin_1_beta_1act_integral_to_membrane_v2) or ErbB4_ErbB4_neuregulin_2_beta_neuregulin_2_beta_1act_integral_to_membrane) or ErbB4_JM_B_ErbB4_JM_B_neuregulin_1_beta_neuregulin_1_beta_1act_integral_to_membrane_v1) or GNB1_GNG2_1act_cytoplasm) or Nephrin_NEPH1_podocin_CD2AP_membrane_raft) or Nephrin_NEPH1_podocin_membrane_raft_v1) blue _h_3770_2 (((((((ErbB2_ErbB3_neuregulin_1_beta_1act_integral_to_membrane_v3 or ErbB4_ErbB4_HBEGF_HBEGF_1act_integral_to_membrane) or ErbB4_ErbB4_neuregulin_1_beta_neuregulin_1_beta_1act_integral_to_membrane_v2) or ErbB4_ErbB4_neuregulin_2_beta_neuregulin_2_beta_1act_integral_to_membrane) or ErbB4_JM_B_ErbB4_JM_B_neuregulin_1_beta_neuregulin_1_beta_1act_integral_to_membrane_v1) or GNB1_GNG2_1act_cytoplasm) or Nephrin_NEPH1_podocin_CD2AP_membrane_raft) or Nephrin_NEPH1_podocin_membrane_raft_v1) blue _h_3770_1 (((((((ErbB2_ErbB3_neuregulin_1_beta_1act_integral_to_membrane_v3 or ErbB4_ErbB4_HBEGF_HBEGF_1act_integral_to_membrane) or ErbB4_ErbB4_neuregulin_1_beta_neuregulin_1_beta_1act_integral_to_membrane_v2) or ErbB4_ErbB4_neuregulin_2_beta_neuregulin_2_beta_1act_integral_to_membrane) or ErbB4_JM_B_ErbB4_JM_B_neuregulin_1_beta_neuregulin_1_beta_1act_integral_to_membrane_v1) or GNB1_GNG2_1act_cytoplasm) or Nephrin_NEPH1_podocin_CD2AP_membrane_raft) or Nephrin_NEPH1_podocin_membrane_raft_v1) _h_6341_1 blue FOXO3A_nucleus blue _h_5667 FOXA2_nucleus_v1 grey grey blue _h_3770_9 (((((((ErbB2_ErbB3_neuregulin_1_beta_1act_integral_to_membrane_v3 or ErbB4_ErbB4_HBEGF_HBEGF_1act_integral_to_membrane) or ErbB4_ErbB4_neuregulin_1_beta_neuregulin_1_beta_1act_integral_to_membrane_v2) or ErbB4_ErbB4_neuregulin_2_beta_neuregulin_2_beta_1act_integral_to_membrane) or ErbB4_JM_B_ErbB4_JM_B_neuregulin_1_beta_neuregulin_1_beta_1act_integral_to_membrane_v1) or GNB1_GNG2_1act_cytoplasm) or Nephrin_NEPH1_podocin_CD2AP_membrane_raft) or Nephrin_NEPH1_podocin_membrane_raft_v1) blue _h_3770_8 (((((((ErbB2_ErbB3_neuregulin_1_beta_1act_integral_to_membrane_v3 or ErbB4_ErbB4_HBEGF_HBEGF_1act_integral_to_membrane) or ErbB4_ErbB4_neuregulin_1_beta_neuregulin_1_beta_1act_integral_to_membrane_v2) or ErbB4_ErbB4_neuregulin_2_beta_neuregulin_2_beta_1act_integral_to_membrane) or ErbB4_JM_B_ErbB4_JM_B_neuregulin_1_beta_neuregulin_1_beta_1act_integral_to_membrane_v1) or GNB1_GNG2_1act_cytoplasm) or Nephrin_NEPH1_podocin_CD2AP_membrane_raft) or Nephrin_NEPH1_podocin_membrane_raft_v1) _h_4463 blue (E2_ERA_ERB__dimer__1act_plasma_membrane and Gs_family_GDP_Gbeta_gamma) grey grey _h_3480 blue uPA_uPAR_1act_plasma_membrane_v2 _h_5410_4 blue AS160_2O_1ina_3O _h_5410_5 blue 14_3_3_E blue _h_3190 (E2_ERA__dimer__AIB1_1act_nucleus or IKKs) red red _h_5410_2 blue AS160_2O_1ina_3O _h_5410_3 blue AS160_2O_1ina_3O _h_3486 blue Fibronectin_extracellular_matrix red red _h_1355 blue Endoglin__dimer__integral_to_membrane and TGFBR2__dimer__1act_integral_to_membrane grey blue _h_3484 Fra1_JUN_1act_nucleus grey _h_817_2 blue HBP1 grey grey _h_5404 blue Glucocorticoid_Receptor and PKA_Family_active_1act _h_5405 blue alphav_beta3_Integrin_integral_to_membrane red _h_5407 blue NOTCH1_heterodimer_integral_to_membrane and not Delta_3_integral_to_membrane red blue _h_5401 (Lethal_Factor_cytoplasm or Nalp_1b_1act) blue _h_5402 dNp63b__tetramer__nucleus red _h_5408 blue HDAC1_PITX2_1act_nucleus red grey blue _h_1534 p38_alpha_1O_1O_1act_v2 or p38_beta_1O_1O_1act red _h_1536 blue FZD1_integral_to_membrane _h_6217 blue VEGFA189 _h_1530 blue Lck_1O_1act or Src_1O_1act_plasma_membrane or Syk_1act _h_1247 blue ICAM3 _h_6212 blue ((LAT_PLCgamma1_GRB2_SLP76_GADs or NTAL_PLCgamma1_GRB2_SLP76_GADs) or PLCgamma1_1act_2O) _h_1245 blue (CXCR3_GNAI2_GDP_G_beta_gamma_integral_to_membrane and GTP_v1) grey blue _h_1248 Ubc9 blue _h_1249 FAK_1O_1act_focal_adhesion or Talin blue _h_6218 p53__tetramer__nucleus_v2 grey grey _h_1021_4 blue FAP1 _h_1021_1 blue FAP1 _h_1021_2 blue FAP1 red grey grey grey grey grey grey red _h_6001_2 blue p38_alpha_1O_1O_1act_v2 grey grey grey red blue _h_6027 FOXO3A_nucleus red blue _h_5541 LKB1_nucleus blue _h_5540 TAp63a__tetramer__1act_nucleus_v3 _h_5543 blue (GTP_v1 and (GNB1_GNG2_1act_cytoplasm or PI3K_1act_plasma_membrane_v2)) blue _h_5542 ILK_1act_1p red grey _h_5547 blue CDC37 and ILK _h_5546 blue RasGAP_1act grey red red blue _h_6026 p53__tetramer__nucleus_v2 grey blue _h_322 JUN_JUND_1act_nucleus red grey grey blue _h_4499 RPA_ATR_ATRIP_RAD17_RFC2_5_9_1_1_TopBP1_1act_nucleus blue _h_320 (((JUN_FOSNFAT1_c_4_1act_nucleus_c_Jun_2O_NFAT1_1O_7O_2s_1act_nucleus_FOS_1O_1O or JUN_FOSNFAT1_c_4_1act_nucleus_c_Jun_2O_NFAT4_1act_nucleus_FOS_1O_1O) or JUN_FOSNFAT1_c_4_1act_nucleus_c_Jun_2O_NFATc_1act_nucleus_FOS_1O_1O) and ( not ((JUN_NFAT1_c_4_p21SNFT_1act_nucleus_c_Jun_2O_NFAT1_1O_7O_2s_1act_nucleus_p21SNFT or JUN_NFAT1_c_4_p21SNFT_1act_nucleus_c_Jun_2O_NFAT4_1act_nucleus_p21SNFT) or JUN_NFAT1_c_4_p21SNFT_1act_nucleus_c_Jun_2O_NFATc_1act_nucleus_p21SNFT))) _h_315 blue SMAD2_SMAD2_SMAD4_FOXH1_1act_nucleus _h_5893 blue GR_alpha_HSP90_FKBP51_HSP90 and cortisol _h_5892 blue alpha4_beta1_Integrin_integral_to_membrane_v1 grey blue _h_5890 Arf6_GTP_1act grey grey blue _h_5895 Gangliosides_and_protein_receptor__synaptotagmin_I_and_II__extracellular_region grey grey grey grey blue _h_681 TCR_CD3_MHC_I_CD8_1act_integral_to_membrane and not IL12_IL12R_TYK2_JAK2_1act_integral_to_membrane blue _h_5051_37 (RAS_family_GTP_1act_plasma_membrane_H_RAS_isoform_1_GTP_v1 or RAS_family_GTP_1act_plasma_membrane_N_RAS_GTP_v1) grey grey grey blue _h_908 RasGAP_Csk grey _h_2005_2 blue uPAR_DII_DIII_plasma_membrane _h_2005_1 blue uPAR_DII_DIII_plasma_membrane grey grey grey blue _h_329 not ATM_TRF2 blue _h_808 (SP1 or TAp73b__tetramer__nucleus) red red red _h_701 blue GTP_v1 and not RHOGDI and (APC_ASEF_1act or ARHGEF2_1act or ASEF2_1act or Arf6_GTP_1act_plasma_membrane or DBL_1act or DEF6_1act or DOCK1_1act or DOCK1_ELMO1_1act or DOCK2_1act or DOCK6_1act or EGFR_EGFR_EGF_EGF_1act_integral_to_membrane_v4 or ELMO1 or Ephexin_1act or GEFT_1act or KALRN_1act or KALRN_plasma_membrane or PDGF_BB_PDGFRB__dimer__GAB1_N_WASP_NCK1_2_1act_integral_to_membrane_v2_PDGFRB_11O_NCK1_PDGFB_v1_N_WASP_Gab1_1O or PDGF_BB_PDGFRB__dimer__GAB1_N_WASP_NCK1_2_1act_integral_to_membrane_v2_PDGFRB_11O_NCK2_PDGFB_v1_N_WASP_Gab1_1O or PI3K_1act_plasma_membrane_v2 or PREX1_1act or PREX2_1act or RAP1GDS1_1act or RASGRF1_1act or RASGRF2_1act or SOS1_Eps8_ABI1 or SOS1_Eps8_ABI1_1act or TRIO_1act or Tiam1_1act or Tiam2_1act or VAV1_1act or VAV2_1act or VAV2_1act_plasma_membrane or Vav3_1act or alphaPIX__dimer__1act or betaPIX_1act or beta_2_chimerin_1act_plasma_membrane or p130_Cas_1p_1act) red _h_370 blue FAK_p130_Cas_Paxillin_membrane_raft_v2 and GTP_v1 grey _h_800 blue Phosphatidylcholine and SMS and not Acid_Sphingomyelinase grey grey grey red red grey red red grey grey red _h_6200 blue TAp73a__tetramer__nucleus_v6 blue _h_4946 MYC_Max_nucleus_v2 _h_4947 blue JUN_2O_1act_nucleus _h_4944 blue CD147 and Cyclophilin_B blue _h_4945 EGR3 _h_4942 blue (GDP_v1 and MgcRacGAP_1act) red blue _h_3042 DAG_v2 grey grey _h_761_2 blue Actin and alpha_actinin_1O_cytoplasm red red red red grey _h_6309 blue alpha9_beta1_Integrin_integral_to_membrane grey grey grey red _h_2713_2 blue SMAD4_cytoplasm grey grey red _h_685 blue proMMP_2 grey red grey grey grey red grey red grey blue _h_1036_99 Arf6_GTP_1act or Arf6_GTP_1act_plasma_membrane blue _h_1036_96 Arf6_GTP_1act or Arf6_GTP_1act_plasma_membrane blue _h_1036_97 Arf6_GTP_1act or Arf6_GTP_1act_plasma_membrane blue _h_1036_94 Arf6_GTP_1act or Arf6_GTP_1act_plasma_membrane red blue _h_1036_92 Arf6_GTP_1act or Arf6_GTP_1act_plasma_membrane blue _h_1036_93 Arf6_GTP_1act or Arf6_GTP_1act_plasma_membrane blue _h_1036_90 Arf6_GTP_1act or Arf6_GTP_1act_plasma_membrane blue _h_1036_91 Arf6_GTP_1act or Arf6_GTP_1act_plasma_membrane grey grey grey grey blue _h_2944_5 not E_cadherin_cytoplasm and (MAPK_14 or p120ctn) red grey grey grey red red _h_3076_1 blue SMAD2_3_SMAD4_1act_nucleus_SMAD2_2O_1act_SMAD4 grey red _h_106 blue Type_III_Collagen_extracellular_region red _h_3263_9 blue FGFR1c_FGF6_1act grey blue _h_3231 ROCK1_1act blue _h_104 (( not Myb) and (CEBPB or STAT6__dimer__1act_nucleus_v1)) _h_4943_2 blue E2_integral_to_membrane grey grey grey _h_102 blue CRK_II_cytoplasm and DOCK1 blue _h_2381_3 Akt1_1O_1O_1act_plasma_membrane grey grey grey grey red grey grey red grey grey _h_553 blue JUN_FOS_1act_nucleus_v4 grey red red red grey red red blue _h_3968 CDC42_GTP_1act_plasma_membrane or PKC_beta_1act_plasma_membrane or PKC_isoenzymes_1act_plasma_membrane or PRKCG_1act_plasma_membrane _h_557 blue PIASy and SMAD4_cytoplasm grey _h_40_2 blue Gamma_Secretase_1act grey grey _h_40_1 blue Gamma_Secretase_1act grey grey grey grey red grey grey _h_1692_1 blue RB1_E2F1_3_DP_HDAC1_nucleus_HDAC1_DP1_RB1_E2F2 grey grey red _h_2458 blue uPA_uPAR_Vitronectin_1act_plasma_membrane blue _h_2459 ( not ((E2F1_3_DP_nucleus_DP1_E2F1 or E2F1_3_DP_nucleus_DP1_E2F2) or E2F1_3_DP_nucleus_DP1_E2F3)) blue _h_2456 CREB1_1act grey grey _h_2455 blue HET red blue _h_2450 not PTEN_1act_cytoplasm and (E2_ER_alpha__dimer__PELP1_Src_PI3K_1act_caveola or Ephrin_A1_EPHA2_PI3K_1act_integral_to_membrane or G_beta_gamma_PI3K_gamma_p84_1act_integral_to_membrane or IL2_IL2R_alpha_beta_gamma_JAK1_LCK_JAK3_SHC_GAB2_GRB2_SOS1_SHP2_PI3K_1act_integral_to_membrane or LAT_GRAP2_SLP76_VAV1_PI3K_Class_IA_1act or LAT_GRAP2_SLP76_VAV1_PI3K_Class_IA_1act_integral_to_membrane or PDGF_BB_PDGFRB__dimer__NHERF1_2_PTEN_1act_integral_to_membrane_PDGFRB_11O_NHERF1_PTEN_1act_PDGFB_v1 or PDGF_BB_PDGFRB__dimer__NHERF1_2_PTEN_1act_integral_to_membrane_PDGFRB_11O_PTEN_1act_NHERF2_PDGFB_v1 or PI3K_1act_cell_cell_junction_v2 or PI3K_1act_plasma_membrane_v1 or PI3K_1act_plasma_membrane_v2 or PI3K_beta_1act_plasma_membrane or PI3K_delta_1act_plasma_membrane or PI3K_gamma_p101_1act_plasma_membrane or PI3K_gamma_p84_1act_plasma_membrane or PI3K_p110_alpha_p55_gamma_1act_plasma_membrane or PI3K_p110_alpha_p85_beta_1act_plasma_membrane or PI3K_p110_beta_p55_gamma_1act_plasma_membrane or PI3K_p110_beta_p85_beta_1act_plasma_membrane or PI3K_p110_delta_p55_gamma_1act_plasma_membrane or PI3K_p110_delta_p85_beta_1act_plasma_membrane or PTEN_cytoplasm or PTEN_v1 or PTEN_v2 or RAS_family_GTP_PI3K_1act_plasma_membrane_PIK3R1_H_RAS_isoform_1_p110_alpha_GTP_v1 or RAS_family_GTP_PI3K_1act_plasma_membrane_PIK3R1_N_RAS_p110_alpha_GTP_v1 or RAS_family_GTP_PI3K_Class_I_1act_plasma_membrane_PI3K_H_RAS_isoform_1_GTP_v1 or RAS_family_GTP_PI3K_Class_I_1act_plasma_membrane_PI3K_N_RAS_GTP_v1 or RAS_family_GTP_PI3K_Class_I_1act_plasma_membrane_PI3K_gamma_p84_H_RAS_isoform_1_GTP_v1 or RAS_family_GTP_PI3K_Class_I_1act_plasma_membrane_PI3K_gamma_p84_N_RAS_GTP_v1 or SHC_Grb2_SOS1_GAB1_PI3K_1act_integral_to_membrane) grey _h_6300 blue TRAIL_TRAILR1_FADD_TRADD_RIP_integral_to_membrane grey _h_6125_5 blue PRAS40_1O red grey blue _h_5051_51 (RAS_family_GTP_1act_plasma_membrane_H_RAS_isoform_1_GTP_v1 or RAS_family_GTP_1act_plasma_membrane_N_RAS_GTP_v1) blue _h_5051_50 (RAS_family_GTP_1act_plasma_membrane_H_RAS_isoform_1_GTP_v1 or RAS_family_GTP_1act_plasma_membrane_N_RAS_GTP_v1) grey blue _h_5051_52 (RAS_family_GTP_1act_plasma_membrane_H_RAS_isoform_1_GTP_v1 or RAS_family_GTP_1act_plasma_membrane_N_RAS_GTP_v1) blue _h_5051_55 (RAS_family_GTP_1act_plasma_membrane_H_RAS_isoform_1_GTP_v1 or RAS_family_GTP_1act_plasma_membrane_N_RAS_GTP_v1) blue _h_5051_54 (RAS_family_GTP_1act_plasma_membrane_H_RAS_isoform_1_GTP_v1 or RAS_family_GTP_1act_plasma_membrane_N_RAS_GTP_v1) blue _h_5051_57 (RAS_family_GTP_1act_plasma_membrane_H_RAS_isoform_1_GTP_v1 or RAS_family_GTP_1act_plasma_membrane_N_RAS_GTP_v1) grey blue _h_5051_59 (RAS_family_GTP_1act_plasma_membrane_H_RAS_isoform_1_GTP_v1 or RAS_family_GTP_1act_plasma_membrane_N_RAS_GTP_v1) grey _h_3263_2 blue FGFR1c_FGF1_1act grey _h_5861_2 blue (FOXG1 and FOXO1_1act_nucleus) _h_3230 blue IL6_IL6RA_integral_to_membrane grey grey red _h_5199_2 blue RACO_1_1act red _h_4606 blue ABI1 and EGFR_EGFR_EGF_EGF_1act_integral_to_membrane_v1 and SOS1 grey red red _h_4976 blue Caspase_8__tetramer__FADD_FADD_1act _h_2084_2 blue YWHAG _h_2084_3 blue CDC25B_1ina_1O red grey grey grey _h_2084_4 blue YWHAZ grey grey blue _h_4974 Gangliosides_and_protein_receptor__synaptotagmin_I_and_II__extracellular_region red _h_4067 blue Src red red _h_2399 blue netrin_1_extracellular_region blue _h_954 (E2_ERA_nucleus or FOXA1_nucleus) grey blue _h_4971 NF_kappa_B1_RelA_cytoplasm grey red blue _h_6226 PARP1_1act grey blue _h_5192 Akt1_1O_1O_1act red red blue _h_957 dNp73a__tetramer__nucleus_v2 grey red red red red grey grey _h_5455_1 blue WNT3A_LRP6_FZD5_DVL_1act_integral_to_membrane_v3 _h_5455_2 blue WNT3A_LRP6_FZD5_DVL_1act_integral_to_membrane_v3 grey red red red grey red grey grey red _h_4120 blue TCPTP_p45_nucleus red grey _h_4124 blue NDEL1_TACC3_centrosome _h_4125 blue alphav_beta3_Integrin_integral_to_membrane blue _h_4126 PDK1_1act_plasma_membrane or PI_3_4_5_P3_plasma_membrane grey _h_2894_1 blue FOXO1_1O_1ina_2O_nucleus _h_2894_3 blue FOXO4_1O_1ina_2O_nucleus grey _h_2894_5 blue YWHAG_nucleus _h_2894_4 blue FOXO1_1O_1ina_2O_nucleus _h_2894_7 blue FOXO4_1O_1ina_2O_nucleus _h_2894_6 blue YWHAQ_nucleus _h_2894_9 blue FOXO3A_1O_1ina_2O_nucleus _h_2894_8 blue YWHAG_nucleus grey grey red red blue _h_2872 dNp73a__tetramer__nucleus_v2 blue _h_2873 LEF1_beta_catenin_1act_nucleus_v1 grey red blue _h_2876 LEF1_beta_catenin_1act_nucleus_v1 grey grey red red red grey _h_4806_3 blue S1P1_S1P_1act_v1 grey _h_4806_1 blue S1P1_S1P_1act_v1 blue _h_807_51 FASLG_FAS__trimer__Src_Syk_1act_integral_to_membrane or TRAIL__trimer__extracellular_region grey _h_4806_4 blue S1P1_S1P_1act_v1 _h_4806_5 blue S1P1_S1P_1act_v1 blue _h_1707 CaM_Ca2__Calcineurin_A_alpha_beta_B1_1act_v2 grey _h_2216_2 blue (NGF__dimer__p75_NTR__PKA_1act_membrane_raft and RhoA_B_C_GTP_1act_v2) blue _h_4443 Antigen_IgE_Fc_epsilon_R1_LYN_SYK_v2 blue _h_15 AP_2_adaptor_complex or EPS15_1O_plasma_membrane red red blue _h_664 Eosine blue _h_1874 LKB1_MO25_STRADA_STRADB_cytoplasm_v2 grey red _h_1704 blue alpha9_beta1_Integrin_integral_to_membrane red red blue _h_623 MDM2_UBCH5_v2 _h_3160 blue ((GTP_v1 and LAT_GRAP2_SLP76_VAV1_NCK1_1act_integral_to_membrane) and WASP_plasma_membrane) grey blue _h_5899_60 ErbB2_ErbB3_neuregulin_1_beta_1act_integral_to_membrane_v1 red _h_254_1 blue PKC_alpha_1act and alpha6_beta4_Integrin_Laminin_hemidesmosome red grey _h_88 blue Syndecan_4 grey red red grey grey grey grey red grey grey red _h_499 blue ((RAC1_GDP_1ina_v1 and ( not ARF6_GTP_NME1_Tiam1_cell_cell_junction)) and ((EGFR_dimer__1act_cell_cell_junction or PI3K_1act_cell_cell_junction_v2) or VAV2_1act_cell_cell_junction)) blue _h_491 PDGF_PDGFRA_1act blue _h_490 RPA_ATR_ATRIP_RAD17_RFC2_5_9_1_1_TopBP1_1act_nucleus blue _h_493 Arf6_GTP_1act_plasma_membrane blue _h_492 p53__tetramer__nucleus_v2 _h_495 blue ID2 _h_494 blue Arf6_GTP_1act and Tiam1_1act _h_496 blue SIRT1_nucleus blue _h_3477 RBPJ_NICD_MAML1_2_p300_1act_nucleus grey grey grey blue _h_3471 MSK1_1act or MSK2_1act _h_3470 blue alpha4_beta7_Integrin_integral_to_membrane_v1 _h_6255 blue alpha3_beta1_Integrin_integral_to_membrane blue _h_3479 (FOXA1_nucleus or FOXA2_nucleus_v2) _h_1878 blue alpha2_beta1_Integrin_integral_to_membrane grey _h_1404_1 blue SMAD2_2O_1act blue _h_5521 ARF6_GDP_1ina _h_3961 blue PI_4_5_P2_plasma_membrane and Syntenin grey grey grey red grey blue _h_141 STAT6__dimer__1act_nucleus_v1 _h_636 blue HB_Gam and Src_Cortactin blue _h_147 STAT6__dimer__1act_nucleus_v1 blue _h_2168 IP3 _h_1088 blue BACH1 _h_144 blue alpha2_beta1_Integrin_integral_to_membrane blue _h_5028_1 RAC1_GTP_1act_v1 _h_149 blue COL17A1 _h_148 blue Src _h_639 blue G12_G13_cytoplasm and S1P_extracellular_region blue _h_638 LEF1_beta_catenin_1act_nucleus_v1 grey red grey red blue _h_2167 STAT1__dimer__1act_v1 or STAT3__dimer___1act grey grey _h_3262 blue alpha8_beta1_Integrin_integral_to_membrane blue _h_442 Fra1_JUN_1act_nucleus red _h_1162 blue IL4_IL4R_JAK1_IL2R_gamma_JAK3_FES_1act_integral_to_membrane grey red grey grey blue _h_5899_64 ErbB2_ErbB3_neuregulin_1_beta_1act_integral_to_membrane_v1 grey red grey grey blue _h_2637_21 ((GNB1_GNG2_1act_cytoplasm or PDGF_BB_PDGFRB__dimer__1act_integral_to_membrane_v1) or SDF1_CXCR4_JAK2_1act_integral_to_membrane) _h_1959_1 blue 9cRA and RARs_VDR_DNA_Vit_D3_VDR_RAR_alpha_DNA_rna_Vit_D3 _h_1959_2 blue ATRA and RARs_VDR_DNA_Vit_D3_VDR_Rar_gamma1_DNA_rna_Vit_D3 blue _h_2637_22 ((GNB1_GNG2_1act_cytoplasm or PDGF_BB_PDGFRB__dimer__1act_integral_to_membrane_v1) or SDF1_CXCR4_JAK2_1act_integral_to_membrane) blue _h_2614 Fyn_1O_1act or LYN_1act_1O or Lck_1O_1act or Src_1act_1O blue _h_3264 KSR_1act_plasma_membrane or RAS_family_GTP_1act_plasma_membrane_H_RAS_isoform_1_GTP_v1 or RAS_family_GTP_1act_plasma_membrane_N_RAS_GTP_v1 or YWHAZ_YWHAZ grey grey _h_4442 blue DHT_AR_nucleus _h_3265 blue ACTR2__dimer__integral_to_membrane and BMP9__dimer__extracellular_region and FKBP12_ALK1__dimer__1ina_integral_to_membrane blue _h_5899_65 ErbB2_ErbB3_neuregulin_1_beta_1act_integral_to_membrane_v1 grey grey _h_3004 blue NGF__dimer__TRKA_1act_integral_to_membrane and PI3K_nucleus blue _h_3005 cortisol_GR_alpha__dimer__Src_1_nucleus and not Akt1_1O_1O_1act blue _h_3002 p38alpha_beta_MAPKAPK2_1act_MAPKAPK2_4O_1O_p38_alpha_1O_1O_1act_v2 or p38alpha_beta_MAPKAPK2_1act_MAPKAPK2_4O_1O_p38_beta_1O_1O_1act red _h_3000 blue GNB1_GNG2_cytoplasm and GRK2_1act blue _h_1036_115 Arf6_GTP_1act or Arf6_GTP_1act_plasma_membrane grey red grey grey grey red grey red _h_2042 blue betaPIX_1O_1act blue _h_5525 PI_3_4_5_P3 or PI_3_4_5_P3_plasma_membrane grey grey red blue _h_1036_112 Arf6_GTP_1act or Arf6_GTP_1act_plasma_membrane blue _h_3029 Ephrin_A5_EPHA3_4_5_6_7_1act grey grey _h_5231 blue IFN_gamma__dimer_ and not SHP2_1act_1O_cytoplasm red blue _h_4440 (FOXA2_nucleus_v1 and ( not insulin)) red grey blue _h_5524 (AR_T_DHT_nucleus or E6AP) blue _h_3630 MYC_Max_nucleus_v2 grey red red grey grey grey red red grey _h_5639 blue HGF_dimer__MET_dimer__GRB2_1act_integral_to_membrane red red grey grey _h_3742 blue YY1_nucleus grey red grey grey grey _h_5635 blue PP2A_v1 grey red blue _h_5899_69 ErbB2_ErbB3_neuregulin_1_beta_1act_integral_to_membrane_v1 grey grey blue _h_5498 PLK1_1O_1act_kinetochore grey red blue _h_5632 IL23_IL23R_JAK2_TYK2_1act_integral_to_membrane blue _h_5631 LEF1_beta_catenin_1act_nucleus_v1 red _h_3263_55 blue FGFR1c_FGF4_1act blue _h_979 GPC1_TGFB_TGFBR1_TGFBR2_1act_integral_to_membrane_TGFB1__dimer__1act_extracellular_region_GPC1_plasma_membrane_TGFBR2_2O_3O_TGFBR1_1O_2O_1act_integral_to_membrane or GPC1_TGFB_TGFBR1_TGFBR2_1act_integral_to_membrane_TGFB2__dimer__1act_extracellular_region_GPC1_plasma_membrane_TGFBR2_2O_3O_TGFBR1_1O_2O_1act_integral_to_membrane or GPC1_TGFB_TGFBR1_TGFBR2_1act_integral_to_membrane_TGFB3__dimer__1act_extracellular_region_GPC1_plasma_membrane_TGFBR2_2O_3O_TGFBR1_1O_2O_1act_integral_to_membrane blue _h_5630 RHOA_GTP_1act_plasma_membrane blue _h_2203 p53__tetramer__nucleus_v2 blue _h_2202 ((JUN_FOSNFAT1_c_4_1act_nucleus_c_Jun_2O_NFAT1_1O_7O_2s_1act_nucleus_FOS_1O_1O or JUN_FOSNFAT1_c_4_1act_nucleus_c_Jun_2O_NFAT4_1act_nucleus_FOS_1O_1O) or JUN_FOSNFAT1_c_4_1act_nucleus_c_Jun_2O_NFATc_1act_nucleus_FOS_1O_1O) blue _h_2201 PDGF_BB_PDGFRB__dimer__SHP2_1act_integral_to_membrane _h_2200 blue IL2_extracellular_region and Telomerase and mTOR and p70S6K_cytoplasm blue _h_2207 TAp63g__tetramer__1act_nucleus_v2 red blue _h_2205 not dNp63a__tetramer__nucleus_v2 blue _h_2204 ( not (Alpha_Synuclein_HSP70_1_CHIP or Alpha_Synuclein_Torsin_A)) red blue _h_2209 (RB1_nucleus or RUNX2) blue _h_2208 ( not (SP1 or TAp73b__tetramer__nucleus)) blue _h_5492 p38alpha_beta_MAPKAPK2_1act_MAPKAPK2_4O_1O_p38_alpha_1O_1O_1act_v2 or p38alpha_beta_MAPKAPK2_1act_MAPKAPK2_4O_1O_p38_beta_1O_1O_1act blue _h_1616 HRAS_GTP_1act_v1 grey grey grey grey grey red red grey _h_3914 blue RasGAP and (Glucocorticoid_Dexamethasone or MKP1_1act) blue _h_3915 dNp63a__tetramer__nucleus_v2 red blue _h_5021 RSK2_1O_2O_1act red red _h_3912 blue (TGFB_TGFBR2_TGFBR1_STRAP_1act_integral_to_membrane and ( not TGFB_TGFBR2_TGFBR1_PML_SARA_SMAD2_3_AP2B2_1act_early_endosome_v2)) blue _h_3913 (RBPJ_NICD_MAML1_2_p300_1act_nucleus and ( not (RBPJ_NCoR_HDAC1_nucleus_HDAC1_RBPSUH_NCoR2 or RBPJ_NCoR_HDAC1_nucleus_HDAC1_RBPSUH_SMRT__N_CoR2_))) grey _h_5026 blue CaM_Ca2_ _h_4337 blue alpha1_beta1_Integrin_integral_to_membrane _h_19 blue ARA70 _h_3918 blue proNGF__dimer__p75_NTR__Sortilin_1act_integral_to_membrane blue _h_3919 TAp73a__tetramer__nucleus_v3 _h_4332 blue Type_I_Collagen_extracellular_region grey _h_1815 blue GPC1_plasma_membrane grey red grey _h_6288 blue TsAd grey grey grey blue _h_3308 LEF1_beta_catenin_1act_nucleus_v1 _h_3709_3 blue RB1_E2F1_3_DP_HDAC3_nucleus_DP1_E2F1_RB1_HDAC3 _h_3709_2 blue RB1_E2F1_3_DP_HDAC3_nucleus_DP1_E2F3_RB1_HDAC3 _h_3709_1 blue RBBP4 _h_3400_2 blue N_WASP grey red grey grey red blue _h_4233_5 Ephrin_B1_EPHB1_2_1act_integral_to_membrane_v1 grey grey blue _h_1912 TCF4E_beta_catenin_1act_nucleus grey grey blue _h_807_54 FASLG_FAS__trimer__Src_Syk_1act_integral_to_membrane or TRAIL__trimer__extracellular_region grey blue _h_515_6 (IL2_IL2R_alpha_beta_gamma_JAK1_LCK_JAK3_1act_integral_to_membrane or IL4_IL4R_JAK1_IL2R_gamma_JAK3_1act_integral_to_membrane) and not (IL2R_beta_JAK1_LCK_SOCS1_1act_integral_to_membrane or IL2R_beta_JAK1_LCK_SOCS3_1act_integral_to_membrane) red blue _h_515_5 (IL2_IL2R_alpha_beta_gamma_JAK1_LCK_JAK3_1act_integral_to_membrane or IL4_IL4R_JAK1_IL2R_gamma_JAK3_1act_integral_to_membrane) and not (IL2R_beta_JAK1_LCK_SOCS1_1act_integral_to_membrane or IL2R_beta_JAK1_LCK_SOCS3_1act_integral_to_membrane) grey blue _h_515_3 (IL2_IL2R_alpha_beta_gamma_JAK1_LCK_JAK3_1act_integral_to_membrane or IL4_IL4R_JAK1_IL2R_gamma_JAK3_1act_integral_to_membrane) and not (IL2R_beta_JAK1_LCK_SOCS1_1act_integral_to_membrane or IL2R_beta_JAK1_LCK_SOCS3_1act_integral_to_membrane) red grey grey red blue _h_1917 (AR_T_DHT_nucleus or EGR1) _h_6184 blue alphaM_beta2_Integrin_integral_to_membrane _h_6185 blue HRAS_1act_plasma_membrane _h_6186 blue NRIF blue _h_6187 CDC42_GTP_1act_plasma_membrane or RAC1_GTP_1act_plasma_membrane blue _h_6180 ( not (E2F4_DP2_p107_p130_nucleus_DP2_E2F4_p130 or E2F4_DP2_p107_p130_nucleus_DP2_p107_E2F4)) blue _h_1914 LPA_LPA1_2_3_LPA1_plasma_membrane_LPA or LPA_LPA1_2_3_LPA2_plasma_membrane_LPA or LPA_LPA1_2_3_LPA3_plasma_membrane_LPA blue _h_6182 (beta2_estradiol or p53__tetramer__nucleus_v2) blue _h_6183 ROCK1_1act_cell_cell_junction grey blue _h_6188 CD40_CD40L__trimer__TRAF2__trimer__MEKK1_membrane_raft or MEKK1_2O_1act or PAK1_1p_1act or RAC1_GTP_1act_v1 or ROCK2_1act or ROCK_1act or TAK1_1act or p130_CAS_CRK blue _h_6189 PTP1B_plasma_membrane red grey grey red red grey red blue _h_3648 ATF2_2O_1act_nucleus _h_3649 blue uPA_uPAR_1act_plasma_membrane_v2 grey blue _h_3644 not MYC_Max_nucleus_v4 red red grey _h_3640 blue A20 and TNF_TNFR1A red blue _h_3642 Ephrin_B1_EPHB1_2_1act_integral_to_membrane_v1 _h_4450 blue proNGF__dimer__p75_NTR__Sortilin_1act_integral_to_membrane grey grey blue _h_4451 E_cadherin_Ca2__beta_catenin_alpha_catenin_p120_catenin_cell_cell_junction_v1 _h_5426 blue alpha4_beta1_Integrin_integral_to_membrane_v1 grey blue _h_5424 FASLG_FAS__trimer__FADD_FADD_1act_integral_to_membrane or TRAIL_TRAILR2_integral_to_membrane or sTNF_alpha_TNFR1A_TRADD_TRAF2_FADD_1act_endosome _h_5422 blue Fibronectin_extracellular_matrix _h_1810 blue HDAC3_nucleus _h_5420 blue ((GTP_v1 and ( not alphaIIb_beta3_Integrin_paxillin_GIT1_integral_to_membrane)) and (((((ARFGEP100_1act or Ephrin_A1_EPHA2_NCK1_GIT1_1act_cell_cell_junction) or GNAQ_ARNO_plasma_membrane) or Gq_family) or PI3K_1act_plasma_membrane_v2) or alphaIIb_beta3_Integrin_integral_to_membrane)) grey red red blue _h_6238 (( not SIRT1) and (E2F1_DP_nucleus_v2 or SP1)) red _h_1516 blue FASLG__trimer__integral_to_membrane grey _h_1514 blue netrin_1_DCC_1act_integral_to_membrane _h_1515 blue GRAP2_cytoplasm _h_1512 blue IRSP53 grey _h_6230 blue FANCD2_FANCI_chromatin grey _h_6049 blue GLI2_cytoplasm red blue _h_5523 RAX_1act grey grey grey _h_5527 blue TCR_CD3_MHC_II_CD4_LCK_1act_integral_to_membrane and p110_alpha _h_5526 blue Sortilin and proBDNF__dimer__extracellular_region blue _h_419_1 RHOA_GTP_1act_plasma_membrane grey red grey grey grey grey blue _h_6048 ( not ATF2_JUND_1act_nucleus) blue _h_515_4 (IL2_IL2R_alpha_beta_gamma_JAK1_LCK_JAK3_1act_integral_to_membrane or IL4_IL4R_JAK1_IL2R_gamma_JAK3_1act_integral_to_membrane) and not (IL2R_beta_JAK1_LCK_SOCS1_1act_integral_to_membrane or IL2R_beta_JAK1_LCK_SOCS3_1act_integral_to_membrane) grey red blue _h_807_55 FASLG_FAS__trimer__Src_Syk_1act_integral_to_membrane or TRAIL__trimer__extracellular_region grey grey grey grey blue _h_4447 Tie2_Ang2 red grey _h_5989 blue NCoR1_nucleus grey grey red grey blue _h_6324 alpha_actinin_cell_cell_junction grey _h_55_1 blue Delta_1_integral_to_membrane _h_55_2 blue NOTCH3_heterodimer_integral_to_membrane _h_55_3 blue NOTCH3_heterodimer_integral_to_membrane _h_1823_2 blue CK2 and Nucleolin _h_1823_3 blue CK2 and uPA_uPAR_alphav_beta3_Integrin_Vitronectin_1act_integral_to_membrane red red grey grey blue _h_2999 p53__tetramer__nucleus_v2 _h_5015_5 blue PPP2R1A_PPP2CA_PPP2R2A_1act _h_739_2 blue FOXM1B_1O_1act_nucleus_v1 _h_2991 blue SOCS2 _h_5015_6 blue PPP2R1A_PPP2CA_PPP2R2A_1act blue _h_5762 IL12_IL12R_TYK2_JAK2_1act_integral_to_membrane grey _h_5015_3 blue PPP2R1A_PPP2CA_PPP2R2A_1act blue _h_2994 CHK1_2O_1act_nucleus or CHK2_1O_nucleus blue _h_828 (AR_T_DHT_nucleus and ( not EBP1)) blue _h_829 (DHT_AR_nucleus or FOXA1_nucleus) grey grey blue _h_820 JNK_1O_1act_1O blue _h_821 Erk1_1O_1act_1O_nucleus or Erk2_1O_1O_1act_nucleus or PKC_1act blue _h_822 (((ARF1_GTP_1act or FAK_1act_1O) or GRB2_GAB1_plasma_membrane) or Gab1_1act_plasma_membrane) _h_824 blue GRB2_SOS1_cytoplasm grey grey blue _h_827 (((((HRAS_1act_plasma_membrane or HRAS_GTP_1act_v1) or PKC_alpha_1act_plasma_membrane) or PKC_beta_1act_plasma_membrane) or RAS_family_GTP_1act_plasma_membrane_H_RAS_isoform_1_GTP_v1) or RAS_family_GTP_1act_plasma_membrane_N_RAS_GTP_v1) _h_2180 blue MAL_dimer_ red grey _h_2485_2 blue PLC_beta_2_cytoplasm blue _h_1510 Blk_1O_1act_integral_to_membrane or Fgr_1act_1O_integral_to_membrane or Fyn_1O_1act_integral_to_membrane or Hck_1act_1O_integral_to_membrane or LYN_1O_1act_integral_to_membrane or Lck_1O_1act_integral_to_membrane or Src_1act_1O_integral_to_membrane or Yes_1act_1O_integral_to_membrane blue _h_5984 IL23_IL23R_JAK2_TYK2_1act_integral_to_membrane red _h_739_1 blue CBP_nucleus _h_3862_3 blue Src _h_3862_2 blue LYN grey _h_3862_4 blue Fyn grey _h_3302 blue Cyclin_D3_CDK11_p58 red _h_4920 blue AIB1 _h_734 blue zyxin grey red blue _h_4924 CBP_1act_nucleus or STAT1__dimer__1act_nucleus_v3 _h_4925 blue Ephrin_A1_EPHA2_1act_integral_to_membrane grey blue _h_735 (( not (HDAC2_nucleus or p53__tetramer__nucleus_v7)) and ((((BRG1 or GCN5_L_ADA2B_TAF9_nucleus) or HZF_nucleus) or POU4F1_nucleus) or p53__tetramer__nucleus_v3)) blue _h_4928 LKB1_MO25_STRADA_STRADB_cytoplasm_v2 _h_4929 blue VEGFR3_plasma_membrane blue _h_4698 TAp63a__tetramer__1act_nucleus_v3 red red red grey grey grey red grey red red blue _h_2182 ((STAT5A_B__dimer__1act_nucleus or STAT5A__dimer__active_1act_nucleus_v2) or STAT5B__dimer__1act_nucleus) grey grey _h_732 blue PLC_beta_2 red _h_6125_1 blue YWHAS _h_6125_2 blue PRAS40_1O _h_6125_3 blue YWHAQ _h_6125_4 blue YWHAB red _h_6125_6 blue PRAS40_1O grey blue _h_4623 FOXM1B_1O_1act_nucleus_v2 grey blue _h_2183 S1P_S1P3_Gi blue _h_4213 TCPTP_p45_1act grey grey grey grey grey red red red grey grey grey _h_5609 blue Frs2 _h_2756_3 blue CDK4_6_Cyclin_D_CDK4_Cyclin_D1 or CDK4_6_Cyclin_D_CDK4_Cyclin_D2 or CDK4_6_Cyclin_D_CDK4_Cyclin_D3 or CDK4_6_Cyclin_D_CDK6_Cyclin_D1 or CDK4_6_Cyclin_D_CDK6_Cyclin_D2 or CDK4_6_Cyclin_D_CDK6_Cyclin_D3 grey _h_2184 blue TLR1_integral_to_membrane and TLR2_integral_to_membrane grey grey red grey grey grey grey grey grey blue _h_6323 Syk red blue _h_6434 HIF1A_ARNT_nucleus blue _h_6435 Tie2_Ang1_1act grey _h_6437 blue RHOA_GTP_1act and alpha4_beta7_Integrin_integral_to_membrane_v1 grey _h_6431 blue Type_I_Collagen_alpha2_beta1_Integrin_1act_plasma_membrane grey blue _h_6433 PLK1_1O_1act_kinetochore grey grey _h_6439 blue STAT4__dimer__1act_nucleus_v2 grey blue _h_764 STAT6__dimer__1act_nucleus_v1 red grey red red grey grey red red _h_1313_5 blue YWHAG_nucleus grey red red grey grey grey blue _h_1271_2 ((((HePTP or MEK1_1act_cytoplasm) or MEK1_2O_1act_cytoplasm) or MEK2_1act_cytoplasm) or PKC_theta_1act_plasma_membrane) grey grey grey red red red _h_4011_3 blue Sef _h_1313_3 blue FOXO1_1O_2O_nucleus blue _h_762 STAT6__dimer__1act_nucleus_v1 blue _h_4626 SPHK1 or SPHK2 or SPPase1 grey grey red red blue _h_928 MYC_Max_nucleus_v2 blue _h_603 CHK1 or CHK2 grey grey red red blue _h_3141 FAK_1act_1O_cytoplasm or Pyk2_RAFTK_1O_1act_cytoplasm _h_2430 blue DNM1 and TXA2_TP_beta_1ina_integral_to_membrane and not (Gq_family_GTP_EBP50_1ina or RAC1_GTP_1act_v1) blue _h_2431 ((STAT5A_B__dimer__1act_nucleus or STAT5A__dimer__active_1act_nucleus_v2) or STAT5B__dimer__1act_nucleus) grey red _h_2435 blue GMCSF_GMR_alpha_CSF2RB_JAK2__dodecamer__SHC_1act_integral_to_membrane _h_2436 blue LYN grey blue _h_5051_79 (RAS_family_GTP_1act_plasma_membrane_H_RAS_isoform_1_GTP_v1 or RAS_family_GTP_1act_plasma_membrane_N_RAS_GTP_v1) grey blue _h_5429 (HIF1A_ARNT_nucleus or TIF2_nucleus) blue _h_5051_73 (RAS_family_GTP_1act_plasma_membrane_H_RAS_isoform_1_GTP_v1 or RAS_family_GTP_1act_plasma_membrane_N_RAS_GTP_v1) blue _h_5051_72 (RAS_family_GTP_1act_plasma_membrane_H_RAS_isoform_1_GTP_v1 or RAS_family_GTP_1act_plasma_membrane_N_RAS_GTP_v1) blue _h_5051_71 (RAS_family_GTP_1act_plasma_membrane_H_RAS_isoform_1_GTP_v1 or RAS_family_GTP_1act_plasma_membrane_N_RAS_GTP_v1) blue _h_5051_70 (RAS_family_GTP_1act_plasma_membrane_H_RAS_isoform_1_GTP_v1 or RAS_family_GTP_1act_plasma_membrane_N_RAS_GTP_v1) blue _h_5051_77 (RAS_family_GTP_1act_plasma_membrane_H_RAS_isoform_1_GTP_v1 or RAS_family_GTP_1act_plasma_membrane_N_RAS_GTP_v1) blue _h_5051_76 (RAS_family_GTP_1act_plasma_membrane_H_RAS_isoform_1_GTP_v1 or RAS_family_GTP_1act_plasma_membrane_N_RAS_GTP_v1) blue _h_5051_75 (RAS_family_GTP_1act_plasma_membrane_H_RAS_isoform_1_GTP_v1 or RAS_family_GTP_1act_plasma_membrane_N_RAS_GTP_v1) blue _h_5051_74 (RAS_family_GTP_1act_plasma_membrane_H_RAS_isoform_1_GTP_v1 or RAS_family_GTP_1act_plasma_membrane_N_RAS_GTP_v1) grey red grey grey red blue _h_760 (GNB1_GNG2_1act_cytoplasm or RHOA_GTP_1act) grey grey grey grey red red red grey blue _h_6430 cIAP2_cytoplasm blue _h_2434_59 ((EGFR_EGFR_1act_integral_to_membrane_v1 or EGFR_EGFR_EGF_EGF_GRB2_GAB1_1act_integral_to_membrane_v1) and ( not (EGFR_EGFR_1ina_integral_to_membrane or EGFR_EGFR_EGF_EGF_GRB2_GAB1_1ina_integral_to_membrane))) red red red red blue _h_6329 KIF5B_1act or N_cadherin_Ca2__p120_catenin_beta_catenin_gamma_catenin_alpha_catenin_cell_cell_junction _h_4216 blue (CXCL9_extracellular_region and CXCR3_GNAI2_GDP_G_beta_gamma_integral_to_membrane) grey grey blue _h_658 Erk2_1O_1O_1act red grey red grey grey _h_5509_4 blue CRY1_cytoplasm red grey red _h_607 blue Del1 _h_2756_1 blue CDK4_6_Cyclin_D_CDK4_Cyclin_D1 or CDK4_6_Cyclin_D_CDK4_Cyclin_D2 or CDK4_6_Cyclin_D_CDK4_Cyclin_D3 or CDK4_6_Cyclin_D_CDK6_Cyclin_D1 or CDK4_6_Cyclin_D_CDK6_Cyclin_D2 or CDK4_6_Cyclin_D_CDK6_Cyclin_D3 _h_2756_2 blue CDK4_6_Cyclin_D_CDK4_Cyclin_D1 or CDK4_6_Cyclin_D_CDK4_Cyclin_D2 or CDK4_6_Cyclin_D_CDK4_Cyclin_D3 or CDK4_6_Cyclin_D_CDK6_Cyclin_D1 or CDK4_6_Cyclin_D_CDK6_Cyclin_D2 or CDK4_6_Cyclin_D_CDK6_Cyclin_D3 grey grey grey _h_3411 blue PAK1_1O_1O_1act or PAK1_1act _h_4444 blue Type_II_Collagen_extracellular_region grey red blue _h_1167 PLK3_1act_1p grey blue _h_1165 PI3K_1act_plasma_membrane_v2 red blue _h_1163 PIRH2 red _h_1161 blue TGFB_TGFBR2_TGFBR1_Par6_occludin_1act_tight_junction red _h_3177_2 blue RARs_THRs_DNA_SMRT_1ina_THRs_SMRT__N_CoR2__RAR_alpha_DNA_rna and Src_1 and TH_v1 blue _h_6504 STAT1__dimer__1act_v1 _h_3177_1 blue RARs_THRs_DNA_SMRT_1ina_THRs_SMRT__N_CoR2__Rar_gamma1_DNA_rna and Src_1 and TH_v1 red blue _h_1169 ETA_receptor_Endothelin_1_integral_to_membrane grey _h_4102 blue TIMELESS _h_4103 blue GPIbA grey _h_4101 blue Myb_nucleus _h_4106 blue alpha4_beta1_Integrin_Fibronectin_Paxillin_GIT1_trailing_edge blue _h_4104 FOXA2_nucleus_v1 grey grey blue _h_4109 Ca2__cytoplasm or DAG_v2 grey grey grey _h_5855 blue PTCH2_integral_to_membrane blue _h_4507 ( not NFX1_SIN3_HDAC_complex) blue _h_3418 p53__tetramer__nucleus_v2 grey blue _h_5899_38 ErbB2_ErbB3_neuregulin_1_beta_1act_integral_to_membrane_v1 grey blue _h_6201 FOXM1C_2O_1act_nucleus grey red grey red blue _h_6163_3 CaM_Ca2__Calcineurin_A_alpha_beta_B1_1act_v2 or PKC_zeta blue _h_6488 AMPKK1_active_1act_cytoplasm or AMPKK2_active_1act_cytoplasm blue _h_2859 (CEBPB or FOXA1_nucleus) blue _h_2852 (MIZ_1 and ( not MYC_Max_MIZ_1_nucleus)) blue _h_2853 Ca2__v1 or CaM or Edema_factor_cytoplasm _h_2850 blue LRP6_integral_to_membrane and WNT3A_2N_1S_1O_extracellular_region blue _h_6163_1 CaM_Ca2__Calcineurin_A_alpha_beta_B1_1act_v2 or PKC_zeta _h_4504 blue RasGAP and (BDNF__dimer__TRKB_1act_endosome_v2 or NGF__dimer__TRKA_1act_endosome or NT3__dimer__TRKC_1act_endosome or NT_4_5__dimer__TRKB_1act_endosome) red red red _h_4586 blue (( not SHIP) and ((((((((B_cell_antigen_BCR_complex_Btk_LYN_SYK_BLNK_PLCgamma2 or ETA_receptor_Endothelin_1_Gq_GTP_PLC_beta_1act_integral_to_membrane_ET1_ETA_PLC_beta_2_Gq_family_GTP_v1) or ETA_receptor_Endothelin_1_Gq_GTP_PLC_beta_1act_integral_to_membrane_ET1_PLC_beta3_ETA_Gq_family_GTP_v1) or ETB_receptor_Endothelin_1_Gq_GTP_PLC_beta_1act_integral_to_membrane_ETB_ET1_PLC_beta3_Gq_family_GTP_v1) or ETB_receptor_Endothelin_1_Gq_GTP_PLC_beta_1act_integral_to_membrane_ETB_ET1_PLC_beta_2_Gq_family_GTP_v1) or PLC_beta3_1act) or PLC_beta_2_1act_cytoplasm) or PLCgamma1_1act_nucleus) or PLCgamma1_2O_1act_plasma_membrane)) red red blue _h_5899_32 ErbB2_ErbB3_neuregulin_1_beta_1act_integral_to_membrane_v1 red _h_2468 blue Crk grey grey grey red _h_4379 blue HNF4 grey blue _h_5899_30 ErbB2_ErbB3_neuregulin_1_beta_1act_integral_to_membrane_v1 _h_2705 blue alphav_beta3_Integrin red blue _h_4850 ((Fer_1act_1O_cytoplasm or Jak2_1act_1O) or Jak2_1act_8O_cytoplasm) blue _h_3984_1 Caspase_3_1act blue _h_5000 SHP2_1act_plasma_membrane _h_4583 blue Src_1act_1O grey grey _h_5859 blue Insulin_Receptor_Insulin_v2 red _h_4011_8 blue FGFR1b_FGF1_plasma_membrane grey red blue _h_871 (AR_T_DHT_nucleus or ATR_v1) red red grey red grey red blue _h_876 Insulin_Receptor_Insulin_GRB14_PDK1 or cAMP red grey _h_4720 blue RPA_ATR_ATRIP_RAD17_RFC2_5_9_1_1_TopBP1_1act_nucleus grey grey blue _h_5208 E2_ERA__dimer__1act_nucleus blue _h_3451 GRK2 or GRK3 _h_3450 blue TBP_nucleus and not (RB1_E2F1_3_DP_nucleus_v3_DP1_E2F1_RB1 or RB1_E2F1_3_DP_nucleus_v3_DP1_E2F3_RB1 or RB1_E2F1_3_DP_nucleus_v3_DP1_RB1_E2F2) red _h_3452 blue FZD8_integral_to_membrane and LRP6_integral_to_membrane and WNT3A_2N_1S_1O_extracellular_region grey grey _h_3457 blue coatomer_protein_complex_ARF1_GTP_Golgi_to_ER_transport_vesicle_membrane _h_3456 blue Ku_Artemis_DNA_PKcs__dimer__Pol_Mu_site_of_double_strand_break grey blue _h_3458 (TAp73a__tetramer__nucleus_v3 and ( not TAp73a__tetramer__MYC_nucleus)) grey grey grey grey grey _h_4426_2 blue paxillin _h_1040 blue Katanin_60 blue _h_1726 MYC_Max_nucleus_v2 grey grey _h_617 blue ATR and CHK1 grey _h_615 blue HEY1_nucleus _h_1986 blue E2_ERA__dimer__1act_nucleus grey _h_612 blue JUN grey blue _h_1036_57 Arf6_GTP_1act or Arf6_GTP_1act_plasma_membrane blue _h_1808 not p53__tetramer__nucleus_v2 and (SP1_3_nucleus or p53__tetramer__nucleus_v1) grey _h_4913_1 blue FAK_Src_Yes_Fyn_1act_focal_adhesion_v2_Fyn_1O_1act_FAK_6O_1act blue _h_3305 STAT6__dimer__1act_nucleus_v1 _h_4913_2 blue FAK_Src_Yes_Fyn_1act_focal_adhesion_v2_Src_1act_1O_FAK_6O_1act _h_1044 blue SHC_Grb2_SOS1_1act_v2 blue _h_1036_55 Arf6_GTP_1act or Arf6_GTP_1act_plasma_membrane grey blue _h_1045 HIF1A_nucleus grey grey red red grey grey grey grey _h_1049 blue ATM_1act red grey blue _h_6018 JUN_FOS_1act_nucleus_v4 red red _h_4121 blue HB_EGF__63_148__1act_extracellular_region grey blue _h_806 FOXO3A_nucleus grey grey _h_3061 blue TC10_GTP_1act_membrane_raft blue _h_3062 p53__tetramer__nucleus_v2 _h_1302 blue Dnchc2 blue _h_3064 RBPJ_NICD_1act_nucleus _h_3065 blue REA blue _h_3066 MDM2_UBCH5_v2 and not (MDM2_1ina_1O or p53_1O_1O) blue _h_3067 E_cadherin_Ca2__beta_catenin_alpha_catenin_p120_catenin_cell_cell_junction_v1 or nectin_3_dimer__I_afadin_I_afadin_Necl_5_dimer__cell_cell_junction blue _h_3068 FOXM1B_nucleus _h_3069 blue ADAM10_1act_integral_to_membrane or MMP3_1act or MMP7_1act red grey red red red grey red blue _h_2068 SUMO2 red grey red grey red grey grey _h_987 blue Neurofibromin blue _h_804 CBP_1act_nucleus or STAT1__dimer__1act_nucleus_v3 red grey _h_755_2 blue Axin1_APC__beta_catenin_cytoplasm grey grey grey red grey grey red _h_986 blue ACh_synaptic_vesicle blue _h_1981 CBP_nucleus or PCAF or p300_nucleus grey grey _h_2795 blue NGF__dimer__TRKA_1act_integral_to_membrane red grey grey red grey blue _h_4485 E2F1_DP_nucleus_v4 and not KAP1 blue _h_4484 Antigen_IgE_Fc_epsilon_R1_LYN_SYK_v2 grey grey blue _h_429_3 Exportin_1 grey red grey blue _h_4489 HDAC1 or HDAC3 or HDAC7a _h_4488 blue dNp63a__tetramer__nucleus_v2 red blue _h_4083 HIF1A_ARNT_SMAD3_SMAD4_SP1_1act_nucleus grey blue _h_3104 JNK2_1O_1O_1act or RB1_nucleus or p38_alpha_1O_1O_1act_v2 or p38_beta_1O_1O_1act blue _h_1269 ((JUN_FOSNFAT1_c_4_1act_nucleus_c_Jun_2O_NFAT1_1O_7O_2s_1act_nucleus_FOS_1O_1O or JUN_FOSNFAT1_c_4_1act_nucleus_c_Jun_2O_NFAT4_1act_nucleus_FOS_1O_1O) or JUN_FOSNFAT1_c_4_1act_nucleus_c_Jun_2O_NFATc_1act_nucleus_FOS_1O_1O) _h_3103 blue PI3K_cytoplasm grey blue _h_6485 MYC_Max_TRRAP_TIP60_TIP49A_TIP49B_BAF53_nucleus grey blue _h_1323 TNFR1A_Caspase_2_TNF_alpha_FADD_TRADD_RIP_cIAP2_TRAF1_TRAF2_Ask1_RAIDD grey red grey red blue _h_3101 ( not JUNB_FOSB_1act_nucleus) _h_4087 blue HIP_55_2O_1act blue _h_429_5 Exportin_1 blue _h_984 HIF1A_JAB1_1act_nucleus blue _h_803 (( not Calcineurin_A_alpha_beta_B1) and ((STAT4__dimer__1act_nucleus_v2 or TCR_CD3_MHC_II_CD4_1act_integral_to_membrane) or T_bet)) blue _h_2229 Cyclin_B1_CDK1_1act_v1 or PLK1_1O_1act red grey red red red blue _h_2226 TAp63b__tetramer__1act_nucleus_v1 red red red red _h_3650_2 blue FOS_3O_1O_1act_nucleus and ICER1_nucleus and NFATc_1act_nucleus red blue _h_1261 SMAD4_SMAD1_5_8__dimer__1act_nucleus grey blue _h_1262 HPSE_1act or MMP1_1act or MMP7_1act or MMP9_1act grey grey grey grey blue _h_3934 RAP1_GTP_1act_cell_leading_edge blue _h_3935 ILK_1act_1p grey grey _h_3930 blue GTP_v1 and NGF__dimer__TRKA_1act_endosome _h_3931 blue BAK_MCL1_mitochondrion grey grey _h_5718 blue BCL_X grey grey blue _h_2088 JUN_ATF3_1act_nucleus grey red blue _h_2081 Caveolin_1 grey blue _h_2085 AMPKK1_active_1act_cytoplasm or AMPKK2_active_1act_cytoplasm or Erk2_1O_1O_1act or p38_alpha_1O_1O_1act_v2 or p38_beta_1O_1O_1act or p90S6K_1O_1act blue _h_5516_1 (Ca2__cytoplasm or DAG_v2) _h_2087 blue Laminin_Alpha _h_2086 blue TTRAP grey blue _h_5714 ATF2_CREB1_1act_nucleus grey blue _h_2760_6 CK1_alpha or CK1_epsilon red red red grey grey blue _h_2760_3 CK1_alpha or CK1_epsilon _h_3650_3 blue ((ICER1_nucleus and JUN_2O_1act_nucleus) and NFAT4_1act_nucleus) _h_6066 blue BGN_extracellular_matrix and CD14_integral_to_membrane and TLR2_MD2_integral_to_membrane _h_5711 blue SHC_GRB2_SOS1_GAB1_1act_integral_to_membrane _h_254_2 blue PKC_alpha_1act and YWHAZ grey blue _h_1486 Src_1act_1O _h_3475_1 blue (( not p21CIP1_CDK2) and (((CDK2_Cyclin_E1_nucleus or RB1_E2F1_3_DP_nucleus_v2_DP1_E2F1_RB1_2N) or RB1_E2F1_3_DP_nucleus_v2_DP1_E2F3_RB1_2N) or RB1_E2F1_3_DP_nucleus_v2_DP1_RB1_2N_E2F2)) red blue _h_5713 FOXO1_nucleus grey blue _h_5899_45 ErbB2_ErbB3_neuregulin_1_beta_1act_integral_to_membrane_v1 red red blue _h_724 ( not ETA_receptor_Endothelin_1_integral_to_membrane) red blue _h_5724 ((AIB1_nucleus or E2_ERA_nucleus) or FOXA1_nucleus) _h_5196 blue PIN1 _h_5197 blue Ubc9_nucleus blue _h_5194 N_cadherin_Ca2__p120_catenin_beta_catenin_gamma_catenin_alpha_catenin_cell_cell_junction grey _h_5193 blue CRK_II_cytoplasm blue _h_5190 MDM2_KAP1_nucleus _h_5191 blue vWF _h_1758 blue Hsp90 and alphav_beta3_Integrin_Vitronectin_integral_to_membrane red red grey blue _h_1755 TCPTP_p45_cytoplasm or alpha3_beta1_Integrin_1act_integral_to_membrane or uPA_uPAR_1act_plasma_membrane_v2 grey red grey blue _h_1751 ATM or CHK2 _h_1752 blue Erk1_cytoplasm and (MEK1_2O_1act or MEK2_2O_1act) red _h_3666 blue p52_SHC blue _h_3667 CREB1_nucleus and not cortisol_GR_alpha__monomer__nucleus blue _h_3664 p53__tetramer__nucleus_v2 blue _h_3665 CDK2_Cyclin_E1 _h_3662 blue IRF_8 and MYC_Max_nucleus_v4 _h_3663 blue IGF_1R_heterotetramer_IGF2_1act _h_3660 blue uPA_uPAR_alpha3_beta1_Integrin_integral_to_membrane _h_3661 blue (((BAMBI and BMP7__dimer__extracellular_region) and BMPR1A_1B__homodimer__integral_to_membrane) and BMPR2__homodimer__1act_integral_to_membrane) red grey blue _h_3668 (ATF2_2O_1act_nucleus and ( not ATF2_JDP2_nucleus)) red grey grey _h_3475_3 blue (( not p21CIP1_CDK2) and (((CDK2_Cyclin_E1_nucleus or RB1_E2F1_3_DP_nucleus_v2_DP1_E2F1_RB1_2N) or RB1_E2F1_3_DP_nucleus_v2_DP1_E2F3_RB1_2N) or RB1_E2F1_3_DP_nucleus_v2_DP1_RB1_2N_E2F2)) red grey red _h_5448 blue Ephrin_B_EPHB2_1act_integral_to_membrane _h_1287 blue alpha9_beta1_Integrin_integral_to_membrane blue _h_1285 PKR _h_1283 blue RAD17_RFC2_5_1act_nucleus red blue _h_2181 (CSE1L_nucleus or p53__tetramer__nucleus_v8) red blue _h_5441 KSR_2O_1act _h_5442 blue Vitronectin_extracellular_region grey blue _h_5444 Gamma_Secretase_plasma_membrane_v1 _h_5445 blue DVL1_1act_cytoplasm blue _h_1288 AR_RACK1_Src_nucleus _h_1289 blue (RhoA_GDP_1ina_plasma_membrane and (AKAP13_1act or p115RhoGEF_1act)) blue _h_1578 (AR_nucleus or PDEF) _h_1579 blue RYBP_YY1 red grey grey blue _h_1570 FOXM1B_nucleus grey blue _h_3984_2 Caspase_3_1act grey _h_1574 blue VE_cadherin_beta_catenin_alpha_catenin_adherens_junction blue _h_729 MKK7_1act_cytoplasm grey _h_6257 blue HES1_nucleus blue _h_3590 not CD40_CD40L__trimer__TTRAP_integral_to_membrane and (C4BPA_CD40_integral_to_membrane or CD40_CD40L__trimer__TRAF2__trimer__TRAF1_integral_to_membrane or CD40_CD40L__trimer__TRAF6_integral_to_membrane) blue _h_3591 PCAF_nucleus red _h_3594 blue CHD3_nucleus and HDAC_complex_nucleus_v1 and MBD3_nucleus and MTA2_nucleus and p66_alpha_nucleus and p66_beta_nucleus blue _h_2186 MKK4_1O_1act_cytoplasm red _h_3597 blue Aurora_A red _h_663_2 blue SMAD6_7_SMURF1_SMURF1_SMAD6 _h_2187 blue GPC1_plasma_membrane grey grey red grey _h_5508 blue FGFR_FGF_Syndecan_2_FRS2_1act and Src_1O_plasma_membrane _h_4548_1 blue HDAC3_nucleus and RXRs_RARs_NRIP1_9cRA_RXR_alpha_NRIP1_2O_1O_Rar_gamma1_9cRA grey _h_5507 blue alpha6_beta4_Integrin_Laminin_hemidesmosome _h_5506 blue Channel and Lethal_factor__3_molecules_ blue _h_5237 JUN_FOS_1act_nucleus_v4 grey blue _h_5503 JUNB__dimer__1act_nucleus_v3 or MAF__dimer__1act_nucleus blue _h_5502 FOXM1B_nucleus red grey grey grey red _h_2498_1 blue ((RAS_family_GDP_Aiolos_1ina_plasma_membrane_H_RAS_isoform_1_Aiolos_1ina_GDP_v1 and ( not RasGAP_Dok_R_1act)) and (IL2_IL2R_alpha_beta_gamma_JAK1_LCK_JAK3_SHC_GRB2_SOS1_GAB2_1act_integral_to_membrane or SOCS3_RasGAP_1act)) grey grey grey red red red grey grey grey grey red red grey grey red _h_3263_40 blue FGFR1b_FGF10_1act blue _h_5510 NPC red _h_842 blue FADD and FASLG_FAS__trimer__1act_integral_to_membrane and not (cIAP1 or cIAP2 or c_FLIPS) blue _h_843 CaM_Ca2__Calcineurin_A_alpha_beta_B1_1act_v2 blue _h_791 TAp63a__tetramer__1act_nucleus_v3 _h_4714 blue PLD1 blue _h_4713 ((NFAT1_c_4__dimer__EGR4_NFAT1_1O_7O_2s_1act_nucleus_EGR4_nucleus or NFAT1_c_4__dimer__EGR4_NFAT4_1act_nucleus_EGR4_nucleus) or NFAT1_c_4__dimer__EGR4_NFATc_1act_nucleus_EGR4_nucleus) red grey blue _h_4710 ETS2 or Myb_nucleus _h_5447 blue dNp63g__tetramer__nucleus red _h_848 blue p14ARF blue _h_849 IL2_IL2R_alpha_beta_gamma_JAK1_LCK_JAK3_1act_integral_to_membrane blue _h_4719 ATF2_2O_1act_nucleus blue _h_4718 IL27_IL27R_JAK2_TYK2_1act red _h_6050 blue RELN_VLDLR_DAB1 grey grey grey _h_3328 blue p53 red grey grey grey grey red grey blue _h_5423 Myb_Cbp_nucleus grey red grey blue _h_4908 MEKK1_2O_1act blue _h_4909 Caspase_3_1act _h_4678 blue GTP_v1 and SDF1_CXCR4_1act_integral_to_membrane _h_4674 blue WWP1_SMAD7_nucleus red blue _h_4900 Akt1_1O_1O_1act grey blue _h_4906 CDC42_GTP_1act or CDC42_GTP_1act_plasma_membrane or PI_4_5_P2_plasma_membrane blue _h_2381_1 Akt1_1O_1O_1act_plasma_membrane red _h_4905 blue (GTP_v1 and (E_cadherin_Ca2__beta_catenin_alpha_catenin_p120_catenin_cell_cell_junction_v1 or N_cadherin_Ca2__p120_catenin_beta_catenin_gamma_catenin_alpha_catenin_cell_cell_junction)) grey red red red blue _h_6221_2 CAMKK2_1act_cytoplasm or LKB1_MO25_STRADA_STRADB_cytoplasm_v2 grey red grey grey grey blue _h_3337_1 RHOA_GTP_1act_plasma_membrane blue _h_2944_79 not E_cadherin_cytoplasm and (MAPK_14 or p120ctn) red grey grey grey _h_266 blue TACE_1act red _h_264 blue T_DHT_AR_TIF2_nucleus_v1 blue _h_2173 IKK_beta_cytoplasm blue _h_262 PARP1_1act red red _h_261 blue MRN_complex_site_of_double_strand_break blue _h_268 E2_ERA__dimer__1act_nucleus red red _h_3822 blue CK2B_FKBP12_ALK1__dimer__1ina_integral_to_membrane and FKBP12_TGFBR1__dimer__1ina_integral_to_membrane red grey grey blue _h_2944_71 not E_cadherin_cytoplasm and (MAPK_14 or p120ctn) grey red grey red blue _h_3348_2 FAK_Src_Yes_Fyn_1act_focal_adhesion_v2_Fyn_1O_1act_FAK_6O_1act or FAK_Src_Yes_Fyn_1act_focal_adhesion_v2_Src_1act_1O_FAK_6O_1act grey grey grey _h_1905 blue GRB2_cytoplasm and SCF_KIT_1act and SOCS1_cytoplasm blue _h_2944_75 not E_cadherin_cytoplasm and (MAPK_14 or p120ctn) blue _h_6051 FOXO4_nucleus red red _h_6069 blue Akt1_1O_1act_v2 grey blue _h_2637_20 ((GNB1_GNG2_1act_cytoplasm or PDGF_BB_PDGFRB__dimer__1act_integral_to_membrane_v1) or SDF1_CXCR4_JAK2_1act_integral_to_membrane) red red red blue _h_1658_8 ((ETA_receptor_Endothelin_1_G12_GTP_1act_integral_to_membrane or NGF__dimer__TRKA_GRIT_1act_endosome) or alphaV_beta3_Integrin_Osteopontin) blue _h_6418 JUN_FOS_1act_nucleus_v4 _h_6419 blue RAC1_GDP_1ina_v1 blue _h_6416 FOXM1B_HNF6_nucleus blue _h_6417 PI_4_5_P2_plasma_membrane _h_6414 blue NGF__dimer__TRKA_1act_integral_to_membrane and PLCgamma1_3O_1act_cytoplasm red blue _h_6413 NGF__dimer__TRKA_1act_endosome blue _h_6410 Dynactin_1 or EB1 or N_cadherin_Ca2__p120_catenin_beta_catenin_gamma_catenin_alpha_catenin_cell_cell_junction _h_6411 blue EPHA4_integral_to_membrane grey grey grey red red grey _h_1210_1 blue p300_nucleus blue _h_1036_137 Arf6_GTP_1act or Arf6_GTP_1act_plasma_membrane grey grey grey _h_1021_3 blue FAP1 blue _h_654 MMP9 grey grey grey red red blue _h_1658_1 ETA_receptor_Endothelin_1_G12_GTP_1act_integral_to_membrane or NGF__dimer__TRKA_GRIT_1act_endosome or alphaV_beta3_Integrin_Osteopontin grey grey red grey red red red grey blue _h_4159 ((DHT_plasma_membrane or Src_1act_1O) or testosterone_plasma_membrane) blue _h_3681 IL12_IL12R_TYK2_JAK2_1act_integral_to_membrane red grey _h_3682 blue beta_Arrestin2_cytoplasm grey grey grey blue _h_5299 RSK2_1act_3O_1O _h_5298 blue SHP2_cytoplasm blue _h_5295 p15_BID and not BCL_X red red _h_5296 blue Enigma blue _h_5291 IL2_IL2R_alpha_beta_gamma_JAK1_LCK_JAK3_SHC_GAB2_GRB2_SOS1_SHP2_PI3K_1act_integral_to_membrane blue _h_5290 (MIZ_1_nucleus and ( not MYC_Max_MIZ_1_DNMT3A_GFI1_nucleus)) blue _h_5292 not MYC_Max_nucleus_v4 grey grey blue _h_5051_19 (RAS_family_GTP_1act_plasma_membrane_H_RAS_isoform_1_GTP_v1 or RAS_family_GTP_1act_plasma_membrane_N_RAS_GTP_v1) blue _h_6088 p53__tetramer__nucleus_v2 blue _h_5051_15 (RAS_family_GTP_1act_plasma_membrane_H_RAS_isoform_1_GTP_v1 or RAS_family_GTP_1act_plasma_membrane_N_RAS_GTP_v1) grey _h_6087 blue PARP1_nucleus grey blue _h_1900 ( not TAp63a__tetramer__1act_nucleus_v3) _h_6080 blue (ARHGEF2_1act and GTP_v1) red red red red red red red grey _h_6081 blue alphaIIb_beta3_Integrin_integral_to_membrane _h_4076_6 blue FOXO4_nucleus and Ran_GTP_Exportin_1 grey red red grey grey grey blue _h_5544 (( not (SMAD2_3_SMAD4_FOXO1_3a_4_FOXG1_1act_nucleus_FOXO1_3a_4_1act_FOXG1_Smad3_2O_1act_SMAD4 or SMAD2_3_SMAD4_FOXO1_3a_4_FOXG1_1act_nucleus_SMAD2_2O_1act_FOXO1_3a_4_1act_FOXG1_SMAD4)) and (((((SMAD2_3_SMAD4_FOXO1_3a_4_1act_nucleus_v1_FOXO1_Smad3_2O_1act_SMAD4 or SMAD2_3_SMAD4_FOXO1_3a_4_1act_nucleus_v1_FOXO4_SMAD2_2O_1act_SMAD4) or SMAD2_3_SMAD4_FOXO1_3a_4_1act_nucleus_v1_FOXO4_Smad3_2O_1act_SMAD4) or SMAD2_3_SMAD4_FOXO1_3a_4_1act_nucleus_v1_SMAD2_2O_1act_FOXO1_SMAD4) or SMAD2_3_SMAD4_FOXO1_3a_4_1act_nucleus_v1_SMAD2_2O_1act_SMAD4_FOXO3A) or SMAD2_3_SMAD4_FOXO1_3a_4_1act_nucleus_v1_Smad3_2O_1act_SMAD4_FOXO3A)) grey grey grey grey grey red grey blue _h_1036_130 Arf6_GTP_1act or Arf6_GTP_1act_plasma_membrane grey grey grey grey grey grey grey red grey grey red red red _h_1983 blue GFRalpha1_GDNF grey red red red blue _h_1982 E_cadherin_Ca2__beta_catenin_alpha_catenin_p120_catenin_cell_cell_junction_v1 red red red grey blue _h_2145 not CO and (BMAL_CLOCK_NPAS2_nucleus or HEME or NADPH) red grey blue _h_2416 IL12_IL12R_TYK2_JAK2_1act_integral_to_membrane _h_2417 blue HMGB1_integral_to_membrane red _h_2143 blue TRF2 blue _h_2418 ( not (SP1 or TAp73a__tetramer__nucleus_v3)) blue _h_2419 MYC_Max_nucleus_v2 red blue _h_2149 Myb_nucleus red red grey blue _h_1143 RAC1_GTP_1act_v1 grey red blue _h_1144 TCPTP_p45_nucleus blue _h_1147 (E2_ERA__dimer__1act_nucleus and ( not E2_ERA__dimer__DP97_1act_nucleus)) _h_1146 blue EPHA3_4_5_6_7 grey grey grey grey grey red grey grey grey _h_3263_72 blue FGFR1b_FGF10_1act _h_3263_73 blue FGFR1c_FGF5_1act _h_3263_70 blue FGFR1c_FGF5_1act _h_3263_71 blue FGFR1b_FGF1_1act _h_3263_76 blue FGFR1b_FGF3_1act grey _h_3263_74 blue FGFR1b_FGF10_1act _h_3263_75 blue FGFR1c_FGF4_1act red red red grey _h_2438_1 blue FAK_Src_Yes_Fyn_1act_focal_adhesion_v2_Fyn_1O_1act_FAK_6O_1act grey _h_4372 blue alphaM_beta2_Integrin_integral_to_membrane grey red red grey _h_1600_1 blue GC1 grey _h_1600_3 blue GC1 grey red red blue _h_1441 ((CEBPB or STAT6__dimer__1act_nucleus_v1) and ( not (BCL6 or HMGIY))) grey blue _h_3850 FAK_1O_1act_focal_adhesion red red blue _h_5744_2 CaM_Ca2__Calcineurin_A_alpha_beta_B1_1act_v1 red red red _h_4427 blue DAB2IP_1act or Neurofibromin_1act_cytoplasm grey grey grey grey red blue _h_3926 DAG_v2 grey grey grey grey blue _h_5519 IKK_beta _h_152_1 blue Gamma_Secretase_1act _h_3394 blue ADAM12 _h_152_2 blue Gamma_Secretase_1act blue _h_3859 ( not MYC_Max_nucleus_v4) red blue _h_3395 HIF1A_ARNT_nucleus grey red red grey grey _h_3536 blue nectin_1_dimer__I_afadin_I_afadin_nectin_3_dimer__I_afadin_I_afadin grey grey grey grey grey grey grey _h_989 blue EGF_extracellular_region and not E_cadherin_Ca2__beta_catenin_alpha_catenin_p120_catenin_cell_cell_junction_v1 red red blue _h_454 PI3K_PIKE_GTP_1act_nucleus _h_985 blue IL6_IL6RA_integral_to_membrane and not PTPEC _h_3535 blue XRCC4__dimer__Ligase_IV blue _h_983 Akt1_1O_1act_plasma_membrane_v2 blue _h_450 MYC_Max_nucleus_v2 _h_453 blue Syk and not SHP1_1act _h_452 blue alpha4_beta1_Integrin_VCAM1_cell_leading_edge grey red _h_2800 blue ARNT_nucleus and HIF1A_nucleus _h_2720 blue RET51_GFRalpha1_GDNF_DOK1 and RasGAP grey _h_6306_3 blue EPHB1_integral_to_membrane grey grey grey _h_3439 blue Src_1act_1O blue _h_807_56 FASLG_FAS__trimer__Src_Syk_1act_integral_to_membrane or TRAIL__trimer__extracellular_region blue _h_5935 TACE grey grey _h_3431 blue Ephrin_A5_caveola blue _h_2723 TAp73a__tetramer__nucleus_v3 blue _h_3437 MIZ_1 and not MYC_Max_MIZ_1_nucleus blue _h_3436 HIF2A_ARNT_nucleus_v3 or SP1_3_nucleus grey _h_2175_4 blue 9cRA and Cbp_p300_PCAF_nucleus_PCAF_p300 and RAR_alpha grey red blue _h_807_59 FASLG_FAS__trimer__Src_Syk_1act_integral_to_membrane or TRAIL__trimer__extracellular_region grey red blue _h_5931 (( not (CCL11_CXCR3_integral_to_membrane or CXCL13_CXCR3_integral_to_membrane)) and (((((((((CXCL10_CXCR3_integral_to_membrane or CXCL4_CXCR3_integral_to_membrane) or CXCL9_11_CXCR3_1act_integral_to_membrane) or ErbB2_ErbB3_neuregulin_1_beta_1act_integral_to_membrane_v1) or IP3) or PIP3) or PI_4_5_P2_plasma_membrane) or Sphingosine_1_phosphate) or WNT5A_FZD2_1act_integral_to_membrane) or voltage_gated_calcium_channel_complex_1act)) grey red blue _h_6307 MYC_Max_PIM1_nucleus _h_5932 blue IL2_IL2R_alpha_beta_gamma_JAK1_LCK_JAK3_1act_integral_to_membrane grey blue _h_671 GLI1_1act_nucleus _h_670 blue alpha4_beta1_Integrin_Fibronectin_integral_to_membrane blue _h_673 NUR77 and not (cortisol_GR_alpha__dimer__nucleus_v4 or cortisol_GR_alpha__monomer__nucleus) red _h_675 blue Src and Syk _h_674 blue MYC_Max_nucleus_v2 _h_677 blue P_selectin_oligomer and alphaM_beta2_Integrin grey grey grey blue _h_2434_49 ((EGFR_EGFR_1act_integral_to_membrane_v1 or EGFR_EGFR_EGF_EGF_GRB2_GAB1_1act_integral_to_membrane_v1) and ( not (EGFR_EGFR_1ina_integral_to_membrane or EGFR_EGFR_EGF_EGF_GRB2_GAB1_1ina_integral_to_membrane))) grey grey grey red grey red blue _h_807_33 FASLG_FAS__trimer__Src_Syk_1act_integral_to_membrane or TRAIL__trimer__extracellular_region _h_254_3 blue PKC_alpha_1act and alpha6_beta4_Integrin_Laminin_hemidesmosome red red red blue _h_5938 PIM1 grey red red grey red grey grey red grey blue _h_807_30 FASLG_FAS__trimer__Src_Syk_1act_integral_to_membrane or TRAIL__trimer__extracellular_region red grey grey red blue _h_2839 Myb_nucleus grey grey grey grey grey grey grey blue _h_3040 MMP9 or Plasmin or Thrombin _h_3041 blue beta_catenin_APC_nucleus _h_3046 blue E2_integral_to_membrane red _h_3045 blue FGFR_FGF2_complex grey _h_6403_1 blue GTP_v1 and not GAB2_1act_plasma_membrane and (ErbB2_ErbB3_neuregulin_1_beta_SHC_GRB2_SOS1_1act_integral_to_membrane or FRS2_family_GRB2_SOS1_1act or FRS2_family_SHP2_GRB2_SOS1_1act or GMCSF_GMR_alpha_CSF2RB_JAK2__dodecamer__SHC_GRB2_SOS1_1act_integral_to_membrane or GRB2_SOS1_SHC_1act_v1 or GRB2_SOS1_SHC_1act_v2 or RASGRF1_1act_1O or RASGRP1_1O_1act_plasma_membrane or SH2B_family_GRB2_SOS1_1act or SHC_GRB2_SOS1_1act_integral_to_membrane or Src_1act_1O) _h_6403_2 blue ((RAS_family_GDP_1ina_plasma_membrane_N_RAS_GDP_v1 and ( not GAB2_1act_plasma_membrane)) and ((((((((((ErbB2_ErbB3_neuregulin_1_beta_SHC_GRB2_SOS1_1act_integral_to_membrane or FRS2_family_GRB2_SOS1_1act) or FRS2_family_SHP2_GRB2_SOS1_1act) or GMCSF_GMR_alpha_CSF2RB_JAK2__dodecamer__SHC_GRB2_SOS1_1act_integral_to_membrane) or GRB2_SOS1_SHC_1act_v1) or GRB2_SOS1_SHC_1act_v2) or RASGRF1_1act_1O) or RASGRP1_1O_1act_plasma_membrane) or SH2B_family_GRB2_SOS1_1act) or SHC_GRB2_SOS1_1act_integral_to_membrane) or Src_1act_1O)) red grey grey blue _h_185 Fra2_JUN_1act_nucleus_v2 grey blue _h_183 ((CREB1 or HIF1A_ARNT_Cbp_p300_nucleus_HIF1A_ARNT_CBP) or HIF1A_ARNT_Cbp_p300_nucleus_HIF1A_ARNT_p300) _h_182 blue E2F3_DP_nucleus blue _h_181 LEWY_BODY _h_180 blue HIF2A_1h_cytoplasm grey grey grey blue _h_188 MYC_Max_PIM1_nucleus red grey red grey grey grey red grey red _h_1636_2 blue (Cortactin and FGFR1c_FGF2_plasma_membrane) _h_1636_3 blue Cortactin and Src_plasma_membrane _h_1636_1 blue Cortactin and Src_plasma_membrane _h_1636_6 blue (Cortactin and FGFR1c_FGF4_plasma_membrane) _h_1636_7 blue (Cortactin and FGFR1c_FGF5_plasma_membrane) _h_1636_4 blue (Cortactin and FGFR1c_FGF6_plasma_membrane) _h_1636_5 blue Cortactin and Src_plasma_membrane grey _h_1636_8 blue (Cortactin and FGFR1b_FGF3_plasma_membrane) _h_1636_9 blue (Cortactin and FGFR1b_FGF1_plasma_membrane) grey red _h_4727 blue GLI1_1act_nucleus red grey grey red grey grey red red grey red blue _h_68 UCHL1_v1 blue _h_1180 TAp63g__tetramer__SSRP1_1act_nucleus grey _h_1182 blue Fog1_nucleus _h_3853_1 blue DP _h_3853_3 blue DP _h_3853_2 blue E2F1_nucleus blue _h_4058_1 HGF_dimer__MET_dimer__GAB1_SHP2_1act_integral_to_membrane or HGF_dimer__MET_dimer__GRB2_GAB1_SHP2_1act_integral_to_membrane or MEK1_2O_1act_cytoplasm or MEK2_2O_1act_cytoplasm red red red red grey grey red red red _h_3958 blue alpha1_beta1_Integrin_integral_to_membrane red red grey _h_3950 blue ARF1_GTP_Membrin_GBF1_p115 and (PI_4_5_P2 or Phosphatidic_acid) _h_3952 blue (RAC1_GDP_1ina_v1 and (((((((((((((((((((((((((((((((((((((((((((DVL1_1act or DVL2_1act) or DVL3_1act) or ETA_receptor_Endothelin_1_integral_to_membrane) or Ephrin_A1_EPHA2_1act_integral_to_membrane) or Ephrin_A1_EPHA2_Tiam1_1act_integral_to_membrane) or Ephrin_A1_EPHA2_VAV2_VAV3_1act_integral_to_membrane_EPHA2_3O_VAV2_Ephrin_A1) or Ephrin_A1_EPHA2_VAV2_VAV3_1act_integral_to_membrane_EPHA2_3O_Vav3_Ephrin_A1) or Ephrin_B1_EPHB1_2_Tiam1_1act_integral_to_membrane) or Ephrin_B2_EPHB4_1act_integral_to_membrane) or Ephrin_B_EPHB1_1act_integral_to_membrane) or FAK_Src_Yes_Fyn_p130_CAS_CRK_DOCK1_ELMO1_1act_lamellipodium_DOCK1_1act_Crk_Fyn_1O_1act_p130Cas_1O_FAK_6O_1act_ELMO1) or FAK_Src_Yes_Fyn_p130_CAS_CRK_DOCK1_ELMO1_1act_lamellipodium_Src_1act_1O_DOCK1_1act_Crk_p130Cas_1O_FAK_6O_1act_ELMO1) or ILK_betaPIX_PKL) or PI3K_1act_plasma_membrane_v2) or PI3K_1act_v2) or PI3K_beta_1act_plasma_membrane) or PI3K_delta_1act_plasma_membrane) or PI3K_p110_alpha_p55_gamma_1act_plasma_membrane) or PI3K_p110_alpha_p85_beta_1act_plasma_membrane) or PI3K_p110_beta_p55_gamma_1act_plasma_membrane) or PI3K_p110_beta_p85_beta_1act_plasma_membrane) or PI3K_p110_delta_p55_gamma_1act_plasma_membrane) or PI3K_p110_delta_p85_beta_1act_plasma_membrane) or PI_3_4_5_P3_plasma_membrane) or RASGRF1_1act_1O) or RAS_family_GTP_Tiam1_1act_plasma_membrane_Tiam1_H_RAS_isoform_1_GTP_v1) or RAS_family_GTP_Tiam1_1act_plasma_membrane_Tiam1_N_RAS_GTP_v1) or Rac_GEFs_1act) or RhoG_GTP_ELMO1_DOCK1_1act) or Sphingosine_1_phosphate) or TRIO_1act) or Tiam1_1O_1act) or VAV1_1act_1O_cytoplasm) or VAV2_1act) or VAV2_1act_1O) or WNT5A_FZD2_ROR2_dimer__DVL2_1act_endosome) or alphaPIX_1act) or alphaPIX__dimer__1act) or c_Abl_2O_1act) or netrin_1_DCC_DOCK1_ELMO1_1act_integral_to_membrane) or netrin_1_DCC_FAK_Fyn_p130_CAS_1act_integral_to_membrane) or netrin_1_UNC5A_1act_integral_to_membrane) or p130_CAS_CRK_DOCK1_1act)) grey grey blue _h_3956 FAS_FADD_DAXX_Ask1_Caspase_8_Caspase_8_FASLG and not c_FLIPS blue _h_3957 E_cadherin_Ca2__beta_catenin_gamma_catenin_alpha_catenin_p120_catenin_cell_cell_junction_v2 grey red blue _h_3472_1 RHOA_GTP_1act_plasma_membrane grey grey red blue _h_3920 Erk2_1O_1O_1act grey red grey red grey _h_6305 blue ((CCL11_extracellular_region and CXCL10_extracellular_region) and CXCR3_GNAI2_GDP_G_beta_gamma_integral_to_membrane) grey grey red red red grey grey red grey _h_4566 blue Fibrinogen grey grey red red blue _h_6118 Ran_GTPase red grey red grey grey grey blue _h_1776 (AR_T_DHT_nucleus and ( not PATZ)) grey _h_1774 blue GTP_cytoplasm and (GRB2_SOCS1_VAV1_1act_cytoplasm or SHC_GRAP2_1act_cytoplasm or SHC_Grb2_SOS1_1act_v2) blue _h_1775 TCR_CD3_MHC_II_CD4_LCK_ZAP_70_1act_integral_to_membrane grey _h_1773 blue (GTP_v1 and alpha4_beta1_Integrin_Fibronectin_Paxillin_YWHAZ__dimer__cell_leading_edge) grey red _h_5702 blue TACC1 grey grey red red grey red red grey red red grey blue _h_2606 not Ca2__v1 _h_2605 blue Ca2__extracellular_region _h_3603 blue PDGFRA_integral_to_membrane red blue _h_2602 p53__tetramer__nucleus_v2 red _h_2600 blue Axin_ARKADIA_cytoplasm blue _h_3608 HCDH1 blue _h_3609 c_Abl_1act_1O blue _h_2609 RAC1_GTP_1act_cell_cell_junction red blue _h_5462 p53__tetramer__nucleus_v2 blue _h_5463 IKK_complex_ELKS_1act_v2 or IKK_complex_PKC_alpha_1act or IKK_complex_cytoplasm_v2 or IL23_IL23R_JAK2_TYK2_1act_integral_to_membrane _h_5461 blue Jak2_Leptin_Receptor and not SOCS3 blue _h_5466 EPO_EPOR__dimer__JAK2 _h_5467 blue Thrombin blue _h_5464 p53__tetramer__nucleus_v2 _h_470 blue ( not FASLG_FAS__trimer__FADD_FADD_CASP8_CASP8_1act_integral_to_membrane_v1) red grey _h_5468 blue FcgammaRIIB _h_5469 blue SRF_nucleus and not CaMK_IV_nucleus grey grey blue _h_6270 (JUN_FOS_NFAT1_c_4_1act_nucleus and ( not cortisol_GR_alpha__monomer__nucleus)) blue _h_6271 ((STAT5A_B__dimer__1act_nucleus or STAT5A__dimer__active_1act_nucleus_v2) or STAT5B__dimer__1act_nucleus) _h_6276 blue Laminin_11_basement_membrane blue _h_6277 (RXRs_RARs_RXR_alpha_RAR_alpha or RXRs_RARs_RXR_alpha_Rar_gamma1) red red grey grey blue _h_1558 ((STAT5A_B__dimer__1act_nucleus or STAT5A__dimer__active_1act_nucleus_v2) or STAT5B__dimer__1act_nucleus) red blue _h_6432 (NF_kappa_B1_p50_RelA and ( not cortisol_GR_alpha__monomer__nucleus)) red grey grey grey red red red red red grey grey _h_4873 blue SIRT1_nucleus red red grey grey grey grey grey red blue _h_880 (ARA60 or AR_T_DHT_nucleus) grey grey red grey grey grey _h_350 blue SMURF2 and TGFB_TGFBR2_TGFBR1_km23_1_1act_early_endosome red grey grey blue _h_357 DAGLA_1act_growth_cone or DAGLB_1act_growth_cone grey grey red red red blue _h_191 Jnk1_1act_nucleus red grey blue _h_2958 ( not AP_2_alpha__cleaved_) blue _h_2957 CDK2 or CDK4 blue _h_2956 Sema4a_Plexin_D1_integral_to_membrane grey grey grey grey grey blue _h_4733 ATM_3O_1N_site_of_double_strand_break blue _h_4529 PGK_cGMP_1act or PKC_beta_1act_plasma_membrane or PKC_delta_1act_plasma_membrane or PKC_epsilon_1act_plasma_membrane or PKC_isoenzymes_1act_plasma_membrane or PKC_theta_1act_plasma_membrane or PRKCG_1act_plasma_membrane or PRKCH_1act_plasma_membrane _h_4735 blue PDGFRB_integral_to_membrane and PDGF_AB_1act_extracellular_region grey blue _h_4736 ATF2_JUND_1act_nucleus grey grey blue _h_866 p53__tetramer__nucleus_v2 _h_867 blue VEGFB186__dimer__extracellular_region blue _h_860 Parkin_cytoplasm grey blue _h_862 CDC25B or WEE1 red grey red grey grey red red grey grey grey blue _h_5051_81 (RAS_family_GTP_1act_plasma_membrane_H_RAS_isoform_1_GTP_v1 or RAS_family_GTP_1act_plasma_membrane_N_RAS_GTP_v1) blue _h_4656 IL2_IL2R_alpha_beta_gamma_JAK1_LCK_JAK3_1act_integral_to_membrane blue _h_4657 (( not NFI) and ((((((AP1_nucleus or CBP_nucleus) or E2_ERA_nucleus) or FOXA1_nucleus) or Oct_1_nucleus) or SP1_3_nucleus) or p300_nucleus)) _h_4654 blue VEGFR2_integral_to_membrane and VEGFR3_integral_to_membrane blue _h_4655 Erk2_1O_1O_1act red _h_4650 blue NOTCH1_heterodimer_integral_to_membrane grey red grey blue _h_6013_1 RAC1_GTP_1act_v1 grey _h_4659 blue HDAC1_nucleus red red red grey grey grey grey blue _h_3895_3 Ran_GTP_Exportin_1 blue _h_3895_2 Ran_GTP_Exportin_1 blue _h_3895_1 Ran_GTP_Exportin_1 grey blue _h_3895_5 Ran_GTP_Exportin_1 blue _h_3895_4 Ran_GTP_Exportin_1 grey red blue _h_4524 (p38_alpha_1O_1O_1act_v2 or p38_beta_1O_1O_1act) grey grey grey grey grey _h_3126 blue (CalDAG_GEFI_1act_membrane and GTP_v1) grey _h_1920 blue TRAF1_TRAF2 grey _h_240 blue Ephrin_A1_integral_to_membrane grey _h_242 blue IQGAP1_cytoplasm and VEGFR2__dimer__VEGFA__dimer__1act_integral_to_membrane_v1 blue _h_243 nectin_1_dimer__I_afadin_I_afadin_nectin_1_dimer__I_afadin_I_afadin_cell_cell_junction or nectin_2_dimer__I_afadin_I_afadin_nectin_2_dimer_I_afadin_I_afadin_cell_cell_junction red _h_246 blue G12 and S1P_extracellular_region red grey _h_249 blue ADAM28_v2 red red grey red red red red _h_5565_1 blue JUNB_nucleus grey _h_179 blue RIMS1_UNC13B red red grey grey red grey red red _h_388_1 blue DHT_plasma_membrane red _h_173 blue Aurora_B_RasGAP_1ina red _h_3385 blue B7_family_CD28_1act_integral_to_membrane_v2 and ZAP_70 blue _h_6479 JUN__dimer__1act_nucleus_v3 _h_3387 blue AP2_v2 and CD4_plasma_membrane and HIV_Nef red _h_3925 blue alphav_beta3_Integrin_integral_to_membrane grey red blue _h_3382 HIF1A_ARNT_nucleus blue _h_6470 NPC blue _h_176 PI3K_1act_plasma_membrane_v2 or PI3K_1act_v2 _h_6472 blue netrin_1_DCC_FAK_1act_integral_to_membrane grey blue _h_6474 WNT3A_LRP6_FZD5_DVL_Axin1_GSK3_1act_integral_to_membrane_v4 _h_3388 blue ELMO2 _h_6476 blue Gi_family_GNB1_GNG2_GDP_1ina and SMO_1act_integral_to_membrane blue _h_177 Ca2__cytoplasm _h_5927 blue TER_rna _h_5926 blue Tie2_Ang1_1act blue _h_5925 PI_3_4_5_P3_plasma_membrane or RAC1_GTP_1act_plasma_membrane blue _h_5924 not RHOGDI blue _h_5923 PI_3_4_5_P3_plasma_membrane blue _h_5922 NGF__dimer__TRKA_1act_endosome red _h_5920 blue PLGF1__dimer__extracellular_region and VEGFR2_integral_to_membrane grey _h_300 blue CXCR4_integral_to_membrane red grey red grey red grey grey grey grey grey _h_2069_1 blue Crk red _h_4521 blue Gab1_cytoplasm and SHP2 and VEGFR2__dimer__VEGFA__dimer__1act_integral_to_membrane_v1 and eNOS_plasma_membrane grey _h_3538_1 blue NKD2_1m_plasma_membrane _h_3538_3 blue DVL1_cytoplasm grey blue _h_5942 CDK2_Cyclin_A_nucleus or JNK2_1O_1O_1act or Jnk1_1O_1act_1O or p38_alpha_1O_1O_1act_v2 red grey _h_2093 blue Gamma_Secretase_plasma_membrane_v2 grey grey grey red grey red grey blue _h_2597 RagA_B_GTP_RagC_D_GDP red blue _h_2596 Fra2_JUN_1act_nucleus_v2 grey grey red red grey blue _h_5051_36 (RAS_family_GTP_1act_plasma_membrane_H_RAS_isoform_1_GTP_v1 or RAS_family_GTP_1act_plasma_membrane_N_RAS_GTP_v1) blue _h_5051_35 (RAS_family_GTP_1act_plasma_membrane_H_RAS_isoform_1_GTP_v1 or RAS_family_GTP_1act_plasma_membrane_N_RAS_GTP_v1) blue _h_5051_34 (RAS_family_GTP_1act_plasma_membrane_H_RAS_isoform_1_GTP_v1 or RAS_family_GTP_1act_plasma_membrane_N_RAS_GTP_v1) grey blue _h_5051_32 (RAS_family_GTP_1act_plasma_membrane_H_RAS_isoform_1_GTP_v1 or RAS_family_GTP_1act_plasma_membrane_N_RAS_GTP_v1) blue _h_5051_31 (RAS_family_GTP_1act_plasma_membrane_H_RAS_isoform_1_GTP_v1 or RAS_family_GTP_1act_plasma_membrane_N_RAS_GTP_v1) _h_3455_2 blue NFAT1_1ina_21O_nucleus red red blue _h_5051_39 (RAS_family_GTP_1act_plasma_membrane_H_RAS_isoform_1_GTP_v1 or RAS_family_GTP_1act_plasma_membrane_N_RAS_GTP_v1) blue _h_5051_38 (RAS_family_GTP_1act_plasma_membrane_H_RAS_isoform_1_GTP_v1 or RAS_family_GTP_1act_plasma_membrane_N_RAS_GTP_v1) red _h_2894_2 blue FOXO3A_1O_1ina_2O_nucleus red red red red _h_2069_2 blue LAT_GRAP2_SLP76_HPK1_HIP_55_1act_integral_to_membrane grey grey red grey red _h_2382 blue GULP grey blue _h_2381_2 Akt1_1O_1O_1act_plasma_membrane red _h_2387 blue E2_ERB__dimer__1act_nucleus _h_2384 blue A20 _h_4968 blue E_cadherin_gamma_catenin_alpha_catenin_basolateral_plasma_membrane and p120_catenin_cytoplasm _h_2388 blue alphav_beta3_Integrin_CD47_integral_to_membrane _h_2389 blue POLL _h_1928 blue Erk2_1O_1O_1act blue _h_3260 JUN_FOS_1act_nucleus_v4 blue _h_4969 MKK7_1act red grey red blue _h_949 ( not JUN_FOS_1act_nucleus_v4) red _h_1070 blue GNAT2_GDP_1ina grey blue _h_2598 Akt1_1O_1O_1act grey grey red grey _h_5400 blue GTP_v1 and cortisol red grey grey grey grey blue _h_1036_118 Arf6_GTP_1act or Arf6_GTP_1act_plasma_membrane grey red _h_3169 blue RanBP2_cytoplasm and Ubc9 red _h_2164 blue alpha9_beta1_Integrin_integral_to_membrane blue _h_2165 not CO and (BMAL_CLOCK_NPAS2_nucleus or HEME or NADPH) _h_941 blue netrin_1_extracellular_region blue _h_2160 MYC_Max_nucleus_v2 _h_2161 blue AURKAIP1 and Antizyme1 grey _h_1129 blue Bile_acids and MED1 and RXRs_FXR _h_4075 blue Antigen_IgE_Fc_epsilon_R1_LYN_SYK_v2 and LAT blue _h_5187 CEBPA_nucleus or Myb_nucleus or SPI1_nucleus grey red blue _h_1120 p38_alpha_1O_1O_1act_v2 or p38_beta_1O_1O_1act red blue _h_1126 Gangliosides_and_protein_receptor__synaptotagmin_I_and_II__extracellular_region blue _h_1125 alpha9_beta1_Integrin_VEGFA__dimer__integral_to_membrane blue _h_1124 CK2A1_1act or GRK5_1O_1O_1act grey _h_3263_58 blue FGFR1c_FGF5_1act _h_3263_59 blue FGFR1c_FGF1_1act red grey _h_3263_54 blue FGFR1c_FGF1_1act red _h_3263_56 blue FGFR1b_FGF1_1act blue _h_4071 (AR_T_DHT_nucleus and ( not HDAC7_nucleus)) _h_3263_50 blue E_cadherin_Ca2__beta_catenin_alpha_catenin_p120_catenin_cell_cell_junction_v1 _h_3263_51 blue FGFR1b_FGF3_1act _h_3263_52 blue FGFR1c_FGF4_1act grey grey grey grey red blue _h_3960 p21CIP1_1act red red grey grey blue _h_3137 p53__tetramer__nucleus_v2 _h_1366 blue IRS1 grey red grey red grey red blue _h_6487 TAp63b__tetramer__1act_nucleus_v1 grey grey blue _h_1712 not CO and (BMAL_CLOCK_NPAS2_nucleus or HEME or NADPH) red blue _h_4203 ARNO_1act_cytosol or BIG1_2_cytosol or CYTOHESIN_1_4_cytosol or PI_4_5_P2 blue _h_2880 ((PGD2_DP or PGI2_IP) or Syndecan_2_Neurofibromin) _h_6239 blue Ku_Artemis_DNA_PKcs__dimer__site_of_double_strand_break_v2 _h_5560 blue CD14_integral_to_membrane and TLR4_MD2_integral_to_membrane grey grey grey grey red _h_293 blue S1P_extracellular_region blue _h_1863 PTP1B_plasma_membrane _h_1717 blue TGFB_TGFBR2_TGFBR1_1act_integral_to_membrane blue _h_1036_114 Arf6_GTP_1act or Arf6_GTP_1act_plasma_membrane grey grey grey red grey red _h_1867 blue ATF2_2O_1act_nucleus _h_29_1 blue Cbp_p300_PCAF_nucleus_PCAF_CBP and Rar_gamma1 and TIF2 red _h_98 blue heparin red red grey grey blue _h_1865 Jnk1_1act red _h_3415 blue RXR_alpha _h_3414 blue Nephrin_NEPH1_cell_cell_junction _h_3417 blue FKBP12_TGFBR1__dimer__1ina_integral_to_membrane and TGFB3_TGFBR2_Endoglin__dimer__1act_integral_to_membrane grey grey _h_3410 blue ErbB3_integral_to_membrane and neuregulin_2_extracellular_region red grey grey red blue _h_3419 GLI2A_1act_nucleus grey grey _h_2438_2 blue FAK_Src_Yes_Fyn_1act_focal_adhesion_v2_Src_1act_1O_FAK_6O_1act blue _h_807_50 FASLG_FAS__trimer__Src_Syk_1act_integral_to_membrane or TRAIL__trimer__extracellular_region grey grey grey grey _h_3971 blue GRB2_SOS1_cytoplasm grey red grey _h_3977 blue TACI red red blue _h_1036_117 Arf6_GTP_1act or Arf6_GTP_1act_plasma_membrane grey grey grey grey red grey red blue _h_2112 Fer_1act_1O_cell_cell_junction grey blue _h_3345 HIF1A_ARNT_nucleus grey grey grey grey _h_5719 blue EGFR_integral_to_membrane and ErbB2_integral_to_membrane grey blue _h_1036_120 Arf6_GTP_1act or Arf6_GTP_1act_plasma_membrane grey blue _h_3266 MIZ_1_nucleus and not MYC_Max_MIZ_1_nucleus red blue _h_3038 not MYC_Max_nucleus_v4 _h_5710 blue GPC1_plasma_membrane red _h_5712 blue E2F1_DP_nucleus_v3 and KAP1 red blue _h_477 EGF_EGFR_1act or Insulin_Receptor_Insulin_IRS1_membrane_raft or Insulin_Receptor_Insulin_v2 or Src_1act_1O blue _h_476 MYC_Max_nucleus_v2 blue _h_475 G12_GTP_1act _h_474 blue GATA1_1act_nucleus red blue _h_2115 Vitronectin or alphav_beta3_Integrin _h_471 blue Estrogen_receptor_alpha red blue _h_3344 AP1_nucleus grey _h_296 blue ErbB2_integral_to_membrane and epiregulin_extracellular_region red red grey blue _h_1138 alpha1_beta1_Integrin_TCPTP_p45_integral_to_membrane grey grey _h_3299 blue JUN_nucleus red blue _h_3298 Phosphatidic_acid grey red blue _h_2400 IFN_gamma_IFN_gammaR_JAK1_JAK1_JAK2_JAK2_1act blue _h_3032 (AP1_1act_nucleus or STAT3__dimer___1act_nucleus) blue _h_1036_129 Arf6_GTP_1act or Arf6_GTP_1act_plasma_membrane grey red red blue _h_1036_128 Arf6_GTP_1act or Arf6_GTP_1act_plasma_membrane blue _h_807_6 FASLG_FAS__trimer__Src_Syk_1act_integral_to_membrane or TRAIL__trimer__extracellular_region grey _h_3295 blue alphav_beta5_Integrin_integral_to_membrane grey grey blue _h_2944_78 not E_cadherin_cytoplasm and (MAPK_14 or p120ctn) red grey grey blue _h_555_1 ((((((((((((CD40_CD40L__trimer__TRAF2__trimer__MEKK1_membrane_raft or CD40_CD40L__trimer__TRAF6_integral_to_membrane) or DLK) or GNB1_GNG2_1act_cytoplasm) or IL2_IL2R_alpha_beta_gamma_JAK1_LCK_JAK3_SHC_1act_integral_to_membrane) or MKK3_1O_1O_1act) or MKK6_1O_1O_1act) or MKK6_1act) or RAC1_CDC42_GTP_PAK_family_1act_plasma_membrane_Rac1_PAK1_1act_GTP_v1) or RAC1_CDC42_GTP_PAK_family_1act_plasma_membrane_Rac1_PAK2_1act_GTP_v1) or RAC1_OSM_MEKK3_MKK3_1act_plasma_membrane) or Syk_1O_1act) or TRAF6_MEKK3_1act) red blue _h_2944_73 not E_cadherin_cytoplasm and (MAPK_14 or p120ctn) blue _h_2944_72 not E_cadherin_cytoplasm and (MAPK_14 or p120ctn) red blue _h_2944_74 not E_cadherin_cytoplasm and (MAPK_14 or p120ctn) blue _h_2944_77 not E_cadherin_cytoplasm and (MAPK_14 or p120ctn) red _h_653 blue alphaX_beta2_Integrin_integral_to_membrane blue _h_652 E2_ERA__dimer__1act_nucleus blue _h_651 Fra1_JUNB_1act_nucleus blue _h_650 not SHP2 and (Fyn_1O_1act or TCR_CD3_MHC_II_CD4_LCK_ZAP_70_1act_integral_to_membrane or TCR_CD3_MHC_I_CD8_LCK_ZAP_70_1act_integral_to_membrane) _h_656 blue GMCSF_GMR_alpha_integral_to_membrane blue _h_655 Akt1_1O_1O_1act_plasma_membrane _h_2628 blue SHC_cytoplasm blue _h_807_7 FASLG_FAS__trimer__Src_Syk_1act_integral_to_membrane or TRAIL__trimer__extracellular_region _h_659 blue Fra2_1O_1O_nucleus blue _h_3290 STAT6__dimer__1act_nucleus_v1 blue _h_1036_113 Arf6_GTP_1act or Arf6_GTP_1act_plasma_membrane grey grey _h_1133 blue CD14_integral_to_membrane and TLR6_integral_to_membrane and VCAN_extracellular_matrix grey grey red _h_1581 blue RPA_RAD17_RFC2_5_1act_nucleus _h_3626 blue CLIP170_cytosol grey blue _h_2434_64 ((EGFR_EGFR_1act_integral_to_membrane_v1 or EGFR_EGFR_EGF_EGF_GRB2_GAB1_1act_integral_to_membrane_v1) and ( not (EGFR_EGFR_1ina_integral_to_membrane or EGFR_EGFR_EGF_EGF_GRB2_GAB1_1ina_integral_to_membrane))) red grey red grey grey grey grey grey red red red grey _h_4799_1 blue JUN_JUN_FOS_1act_nucleus_v1_FOS_JUN_2O_2O grey _h_3263_41 blue FGFR1c_FGF6_1act grey grey _h_5488 blue Syndecan_4_SDF1 red _h_4799_2 blue JAB1_nucleus grey _h_3263_46 blue FGFR1b_FGF3_1act blue _h_6237 dNp63g__tetramer__nucleus grey _h_6460 blue NT3__dimer__extracellular_region and not p75_NTR__1N_integral_to_membrane grey grey grey grey grey grey grey red red red _h_1069_1 blue CITED2 and HDAC7a and HIF1A_1h_1ina_1h_cytoplasm and HIF1A_ARNT_nucleus _h_1069_2 blue CBP and CITED2 and HIF1A_1h_1ina_1h_cytoplasm and HIF1A_ARNT_nucleus blue _h_5487 not Cyclosporin_A and (Ca___cytoplasm or NFAT1_1act) grey red red red grey red grey grey blue _h_6111 SCF_KIT_1act grey blue _h_5482 Src_1act_1O grey grey red red red blue _h_2434_60 ((EGFR_EGFR_1act_integral_to_membrane_v1 or EGFR_EGFR_EGF_EGF_GRB2_GAB1_1act_integral_to_membrane_v1) and ( not (EGFR_EGFR_1ina_integral_to_membrane or EGFR_EGFR_EGF_EGF_GRB2_GAB1_1ina_integral_to_membrane))) grey grey red red red red grey grey blue _h_5983 ( not p53_SIRT1_nucleus) red grey grey blue _h_807_1 FASLG_FAS__trimer__Src_Syk_1act_integral_to_membrane or TRAIL__trimer__extracellular_region blue _h_2931 (E2_ERA__dimer__AIB1_1act_nucleus or IKKs) _h_5025_2 blue FAK_Src_Yes_Fyn_1act_focal_adhesion_v2_Fyn_1O_1act_FAK_6O_1act red _h_4578 blue Syndecan_4 grey red red grey grey grey blue _h_2595 alphav_beta3_Integrin_Talin_cell_cell_junction or nectin_1_dimer__I_afadin_I_afadin_nectin_3_dimer_I_afadin_I_afadin_cell_cell_junction _h_2594 blue uPAR_alphaM_beta2_Integrin_1act_integral_to_membrane blue _h_2593 TCF4_beta_catenin_1act_nucleus blue _h_2592 Fyn_1O_1act blue _h_2591 JUNB__dimer__1act_nucleus_v1 _h_2590 blue Laminin_6_basement_membrane red grey red _h_2599 blue GPC1_plasma_membrane blue _h_6291 p38_alpha_1O_1O_1act_v2 or p38_beta_1O_1O_1act _h_4987 blue (RALB_GDP_1ina and SDF1_CXCR4_1act_integral_to_membrane) grey blue _h_6292 ((IL18_IL18R_1act or STAT4__dimer__1act_nucleus_v2) or mTOR_1O_1act) _h_6234 blue CDC42_GTP_1act blue _h_439 (CK2A1 and ( not (PP1 or PP2A_1act_v2))) blue _h_1533 USP7 grey _h_1713 blue CD14_integral_to_membrane and TLR4_MD2_integral_to_membrane blue _h_1714 TAp73a__tetramer__nucleus_v3 red red blue _h_1718 E_cadherin_Ca2__beta_catenin_alpha_catenin_p120_catenin_cell_cell_junction_v1 or RAC1_GTP_1act_plasma_membrane _h_1719 blue CTGF red grey blue _h_3972 GSK3beta_1act red red grey _h_3976 blue HPK1 red blue _h_3974 Caspase_3_1act and not BCL2 _h_4105_3 blue (FOS_3O_1O_1act_nucleus and NFAT1_1O_7O_2s_1act_nucleus) grey blue _h_3978 p53__tetramer__nucleus_v2 blue _h_3979 HIF1A_ARNT_nucleus grey red _h_2621 blue E2F4_DP _h_657_3 blue CTGF and TGFBR2__dimer__1act_integral_to_membrane and betaglycan__dimer__integral_to_membrane_v2 blue _h_2623 PKA_1act blue _h_2622 Tie2_Ang1_1act blue _h_2625 Akt1_1O_1act_1O_1O_plasma_membrane blue _h_2624 ILK or RET51_GFRalpha1_GDNF_SHC_Grb2_SOS1 or RET9_GFRalpha1_GDNF_SHC_Grb2_SOS1 blue _h_3622 DHT_plasma_membrane or testosterone_plasma_membrane grey blue _h_3620 ATF2_2O_1act_nucleus _h_3621 blue AKT2_1O_1act_cytoplasm or Akt1_1O_1act_cytoplasm_v2 or Akt1_1O_1act_plasma_membrane_v2 or RHEB_GTP_1act red blue _h_3627 IFN_gamma_1act_extracellular_region or IL12_IL12R_TYK2_JAK2_1act_integral_to_membrane or IL23_IL23R_JAK2_TYK2_1act_integral_to_membrane or IL27_IL27R_JAK1_1act or IL27_IL27R_JAK2_TYK2_1act blue _h_3624 ROCK2_1act_plasma_membrane blue _h_3625 HIF1A_ARNT_nucleus grey red _h_1110 blue ELF and TGFB_TGFBR2_TGFBR1_1act_integral_to_membrane red red blue _h_5485 MYC_Max_nucleus_v2 _h_5486 blue SHP2_1act_1O_nucleus grey _h_5481 blue Dok5 red red grey red red blue _h_6298 SHP1_1act _h_6294 blue TCR_CD3_MHC_I_CD8_LCK_ZAP_70_1act_integral_to_membrane grey _h_6297 blue VEGFR1_homodimer_VEGFA_homodimer_1act_plasma_membrane blue _h_6290 TCF3_beta_catenin_TERT_BRG1_1act_nucleus grey grey red blue _h_2434_18 ((EGFR_EGFR_1act_integral_to_membrane_v1 or EGFR_EGFR_EGF_EGF_GRB2_GAB1_1act_integral_to_membrane_v1) and ( not (EGFR_EGFR_1ina_integral_to_membrane or EGFR_EGFR_EGF_EGF_GRB2_GAB1_1ina_integral_to_membrane))) red red grey _h_3703 (0) grey _h_4593 (0) grey _h_6055 (0) grey _h_964 (0) grey _h_3764 (0) NRAMP1_gene-_h_3280 _h_478-GADD45_MTK1_MTK1 green _h_1056 (0) grey _h_1704 (0) grey _h_5359 (0) grey _h_3218 (0) _h_5991-B_Myb grey _h_5624 (0) grey _h_4878 (0) grey _h_5155 (0) grey _h_3899 (0) grey _h_4654 (0) grey _h_6309 (0) grey _h_2874_3 (0) grey _h_2874_1 (0) _h_1391-RAG2 grey _h_2882 (0) ARNO_cytoplasm-_h_5758_3 ARNO_cytoplasm-_h_3981 green _h_3679 (5) grey _h_5338 (0) grey _h_972 (0) grey _h_457 (1) grey _h_4968 (0) _h_4281-SMAD1_2O_1act_cytoplasm _h_4281-BMP7_BMPR2_BMPR1A_1B_SMAD6_SMURF1_1ina_integral_to_membrane CDKN2C_gene-_h_2699 _h_2434_10-PI3K_p110_alpha_p55_gamma_1act_plasma_membrane _h_4285-RR1 _h_4284-IFN_gamma_extracellular_region _h_4287-Cyclin_D2 _h_4286-Chromosomal_passenger_complex_1act_chromosome grey _h_4876 (0) grey _h_1861 (0) Dok_R-_h_849 grey _h_5397 (0) alpha9_beta1_Integrin_integral_to_membrane-_h_1036_58 alpha9_beta1_Integrin_integral_to_membrane-_h_1036_59 grey _h_4363 (0) grey _h_3808 (0) alpha9_beta1_Integrin_integral_to_membrane-_h_1036_75 alpha9_beta1_Integrin_integral_to_membrane-_h_1036_57 alpha9_beta1_Integrin_integral_to_membrane-_h_1036_55 grey _h_2094 (0) grey _h_2948 (0) alpha9_beta1_Integrin_integral_to_membrane-_h_1036_9 grey _h_3306 (0) alpha9_beta1_Integrin_integral_to_membrane-_h_1036_100 grey _h_4044 (0) alpha9_beta1_Integrin_integral_to_membrane-_h_1036_87 grey _h_1527 (0) grey _h_1254 (0) grey _h_288 (0) grey _h_6309 (0) alpha9_beta1_Integrin_integral_to_membrane-_h_1036_27 grey _h_2246 (0) alpha9_beta1_Integrin_integral_to_membrane-_h_1036_63 alpha9_beta1_Integrin_integral_to_membrane-_h_1036_61 grey _h_1596 (0) alpha9_beta1_Integrin_integral_to_membrane-_h_1036_132 grey _h_1287 (0) grey _h_4931 (0) grey _h_1704 (0) grey _h_1821 (0) grey _h_4587 (0) grey _h_2164 (0) _h_4460-MYC_Max_TRRAP_GCN5_STAF65G_SPT3_TAF9_TAF10_TAF12_core_Mediator_nucleus PGK1_gene-_h_1395 PGK1_gene-_h_1216 green _h_4111 (45) _h_2434_14-PI3K_p110_beta_p55_gamma_1act_plasma_membrane _h_1645 CEBPA_gene-_h_1324 grey _h_3076_2 (0) grey _h_3076_1 (0) green _h_2654 (1) green _h_136 (2) grey _h_5883 (0) green _h_5608 (2) green _h_5251 (2) green _h_4287 (2) red _h_2208 (1) green _h_4517 (1) green _h_426 (1) grey _h_885 (0) green _h_6238 (1) green _h_3403 (2) green _h_484 (1) grey _h_5229 (0) green _h_2271 (1) green _h_688 (0) green _h_2699 (0) green _h_808 (1) red _h_2418 (1) green _h_1417 (0) grey _h_1416 (0) _h_2979-betaglycan__dimer__integral_to_membrane_v1 _h_2979-TGFB_TGFBR2_TGFBR1_1act_integral_to_membrane _h_2979-FKBP12 _h_2978-alphav_beta3_Integrin_TGFBR2 green _h_6403_1 (1) green _h_6403_2 (8) _h_2971-Involucrin _h_2970-IL6 _h_2973-Sphingosine_1_phosphate _h_2972-TCF4E_beta_catenin_1act_nucleus _h_2972-TLE4_nucleus _h_2975-Cyclin_A _h_2974-NPM1 _h_2977-Necl_5_dimer__integral_to_membrane _h_2977-nectin_1_dimer__I_afadin_I_afadin_nectin_3_dimer_I_afadin_I_afadin_cell_cell_junction _h_2976-NudC_2O_outer_kinetochore_of_condensed_chromosome grey _h_4715 (0) grey _h_3749 (0) grey _h_3420 (0) grey _h_779 (0) grey _h_4624 (0) grey _h_639 (0) grey _h_343 (0) grey _h_5874 (0) grey _h_246 (0) grey _h_1115 (0) grey _h_293 (0) grey _h_3820 (0) grey _h_6176 (0) _h_4759-NF_kappa_B1_p105_RelA_1ina _h_4758-PI_4_5_P2_plasma_membrane _h_4753-MYC _h_4751-IL2_IL2R_alpha_beta_gamma_JAK1_LCK_JAK3_SHC_GRB2_SOS1_GAB2_1act_integral_to_membrane RUNX2_1ina-_h_1290 _h_4757-GMCSF_GMR_alpha_CSF2RB_JAK2__dimer__YWHAZ_SHC_PI3K_1act_integral_to_membrane _h_4755-RAF1_1act _h_4754-alphaM_beta2_Integrin_ICAM4_integral_to_membrane AMPKK2_cytoplasm-_h_6221_4 AMPKK2_cytoplasm-_h_6221_3 JNK-_h_757 JNK-_h_4519_1 JNK-_h_1173_2 grey _h_4387 (0) JNK-_h_3224_2 JNK-_h_1376 JNK-_h_353_1 JNK-_h_729 JNK-_h_4059_1 JNK-_h_3310 JNK-_h_3993 green _h_4622 (0) PP2A_alpha_B56-_h_4404 MIR26A1_rna_gene-_h_6246 grey _h_869 (0) _h_4648-RAP1_GDP_1ina _h_4648-phosphate _h_4630-TCF4_beta_catenin_HBP1_1ina_nucleus Vitronectin_gene-_h_3947 green _h_771 (0) _h_4634-Ephrin_A1_EPHA2_1act_cell_cell_junction _h_4635-TGFB1_TGFBR2_Endoglin_TGFBR1_ALK1_PPP1CA_1act_integral_to_membrane _h_4636-SHP2_1act_1O_nucleus _h_4637-MIR141_rna _h_4638-PDGF_DD_1act_extracellular_region green _h_6188 (7) _h_723-IL8_CXCR2_1act_integral_to_membrane_v1 CIN85_Endophilin-_h_100 _h_430-Fes_1act_1O_cytoplasm grey _h_1129 (0) green _h_4824 (0) 11_cis_retinol-_h_3340 _h_726-p53_1O GRB2_SOS1_GAB_family_Gab1_GRB2_SOS1-_h_5977_2 grey _h_2599 (0) _h_725-PIP5K1A_1act green _h_3770_7 (1) green _h_3770_6 (1) green _h_3770_5 (1) green _h_3770_4 (1) green _h_3770_3 (1) green _h_3770_2 (1) green _h_3770_1 (1) green _h_3770_9 (1) green _h_3770_8 (1) green _h_805 (0) red _h_3078 (1) _h_3133 _h_3133 green _h_6479 (0) green _h_5476 (0) red _h_5143 (0) green _h_1459 (1) green _h_54 (0) NFATc4_1p_cytoplasm-_h_1845 _h_222-FGFR3c__cleaved__cytoplasm _h_223-E_cadherin_beta_catenin_alpha_catenin_1ina_endosome _h_220-netrin_1_DCC_DOCK1_ELMO1_1act_integral_to_membrane _h_221-ErbB4_ErbB2_HBEGF_1act_integral_to_membrane _h_226-HGF_dimer__MET_dimer__1act_nucleus _h_227-Par3_1act_1O grey _h_5791 (0) grey _h_3806 (0) _h_2944_4-FGFR1b_FGF1_nucleus CENP_A_gene-_h_6425 grey _h_768 (0) green _h_3916 (0) green _h_5831 (0) green _h_5572 (0) grey _h_276 (0) grey _h_4798 (0) _h_4288-PKC_zeta_1act_1p_plasma_membrane _h_4493_1-TSC1_TSC2_1act _h_4493_1-REDD1_14_3_3_family_REDD1_YWHAS _h_1450_1-HIF1A_ARNT_Cbp_p300_Src_1_nucleus_Src_1_HIF1A_ARNT_CBP green _h_1124 (1) green _h_3408 (1) green _h_839 (0) _h_1450_2-HIF1A_ARNT_Cbp_p300_Src_1_nucleus_Src_1_HIF1A_ARNT_p300 green _h_451 (1) grey _h_2509 (0) grey _h_6317 (0) grey _h_3362 (0) green _h_2056 (0) green _h_2461 (9) green _h_735 (8) green _h_3843 (9) red _h_6098 (3) red _h_2176 (0) red _h_4200 (2) red _h_1881 (2) _h_6452-alpha_catenin_cytoplasm _h_6452-E_cadherin_beta_catenin_early_endosome_v3 _h_6453-NuMA__cleaved_by_caspase_3_ _h_6450-FANCE_1O_1O _h_6450-FANCA_FANCB_FANCC_FANCF_FANCG_FANCL_UBE2T_HES1_FAAP100_chromatin grey _h_5649 (0) green _h_335 (137) _h_186_1-KLHL12_Cul3_DVL _h_2139_4 red _h_1518 (11) _h_6229_5-p27Kip1_14_3_3_family_1ina_cytoplasm_YWHAB_p27Kip1_1O _h_6229_5-p27Kip1_KPNA1_1act Caspase_10_1ina-_h_2136 S1P1_S1P_1act_v1-_h_5002 green _h_3578 (1) grey _h_2934 (0) green _h_4848 (0) grey _h_4806_2 (0) grey _h_4806_3 (0) grey _h_4806_1 (0) grey _h_4806_4 (0) grey _h_4806_5 (0) green _h_291 (4) _h_3367-FAS__trimer__LFG_1ina_integral_to_membrane _h_3365-RAF1_1ina_1O_cytoplasm _h_3364-VEGFR2 _h_3363-SOS1_Eps8_ABI1 green _h_5434 (0) _h_3360-MYC_nucleus _h_5901-CD95 _h_5900-AR_T_DHT_nucleus _h_5905-NF_kappa_B2_p52_RelB_1act_nucleus _h_5907-p21CIP1 _h_5906-T_DHT_AR_RACK1_Src_nucleus Insulin_responsive_Vesicles_cytoplasm-_h_2775 green _h_5931 (8) green _h_4017 (0) green _h_2488 (0) _h_1393-VEGFR1_homodimer_NRP2_VEGFR121_plasma_membrane grey _h_1543 (0) _h_3210_1-Ephrin_B1_EPHB1_2_1act_integral_to_membrane_v1 _h_3210_2-Ephrin_B1_EPHB1_2_1act_integral_to_membrane_v1 Caspase_2s_gene-_h_1691 _h_3323-IL6_IL6RA_gp130__dimer__JAK1_JAK1_LMO4_Hck_1act_integral_to_membrane grey _h_6038 (0) grey _h_6305 (0) _h_171_1-SHARP _h_171_1-RBPJ_NICD_MAML1_2_1act_nucleus _h_171_2-SHARP _h_171_2-RBPJ_NICD_MAML1_2_1act_nucleus _h_458-GDP_v1 _h_458-RAB5_GTP_1act_v2 _h_5283-IL6_IL6RA_gp130__dimer__JAK1_JAK1_LMO4_SOCS3_1act_integral_to_membrane IL8_CXCR2_beta_Arrestin1_2_AP_2_1act_integral_to_membrane_AP_2_adaptor_complex_beta_Arrestin2_CXCR2_4O_IL8-_h_754_1 grey _h_4075 (0) MKP1_1act_nucleus_gene-_h_4340 JNK2_cytoplasm-_h_5173_2 green _h_5458 (1) grey _h_3336 (0) SPHK2-_h_851 grey _h_1964 (0) green _h_4626 (1) green _h_3866 (1) grey _h_2062_2 (0) grey _h_2062_1 (0) _h_5280-p107 Dmp1_gene-_h_4344 green _h_6436 (1) green _h_2345 (1) green _h_2327 (1) green _h_1888 (1) green _h_4491 (5) green _h_2534 (1) green _h_1914 (1) RB1_E2F1_3_DP_SUV39H1_nucleus_DP1_SUV39H1_RB1_E2F2-_h_2756_1 pro_MMP12_1ina_extracellular_region-_h_5651 green _h_6383 (1) grey _h_3662 (0) green _h_1168 (7) grey _h_6411 (0) grey _h_4549 (0) grey _h_3995_1 (0) green _h_2232 (3) green _h_4976 (0) grey _h_3036 (0) _h_4297_1-PDGF_BB_PDGFRB__dimer__GAB1_N_WASP_NCK1_2_1act_integral_to_membrane_v2_PDGFRB_11O_NCK2_PDGFB_v1_N_WASP_Gab1_1O mimitin_gene-_h_450 _h_2368-WNT3A_FZD5_LRP6_1act_integral_to_membrane_v1 _h_2369-Syndecan_4_PKC_alpha _h_2369-Syndecan_4_PI_4_5_P2_PKC_alpha _h_2369-PKC_alpha_1act RAF1_14_3_3__dimer__1ina_cytoplasm_RAF1_2O_YWHAS-_h_2392_4 _h_2364-HEY2_GATA4_nucleus _h_2366-RPA_ATR_ATRIP_RAD17_RFC2_5_9_1_1_TopBP1_CEP164_TIMELESS_TIPIN_CLASPIN_1act_nucleus Laminin_alpha4_gene-_h_4791 grey _h_1443 (0) grey _h_3546 (0) YY1_nucleus-_h_1981 grey _h_2221 (0) grey _h_3742 (0) grey _h_3154 (0) grey _h_2377 (0) grey _h_6382 (0) _h_2363-STAT1__dimer__1act_nucleus_v4 grey _h_3958 (0) grey _h_5833 (0) 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IL2R_alpha_integral_to_membrane_gene-_h_6402 IL2R_alpha_integral_to_membrane_gene-_h_412 IL2R_alpha_integral_to_membrane_gene-_h_6339 IL2R_alpha_integral_to_membrane_gene-_h_1745 IL2R_alpha_integral_to_membrane_gene-_h_802 IL2R_alpha_integral_to_membrane_gene-_h_2010 ET1_gene-_h_4573 ET1_gene-_h_2129 _h_4580_1-PLC_beta_2_1act_plasma_membrane _h_5411-Nalp_1b_1act _h_4580_2-PLC_beta3_1act_plasma_membrane _h_2751_3-SIK3_14_3_3_family_cytoplasm_14_3_3_E_SIK3_1O_1act _h_2751_2-SIK3_14_3_3_family_cytoplasm_YWHAB_SIK3_1O_1act red _h_4207 (0) _h_4149-SMARCD3 grey _h_3004 (0) 4_1BB_gene-_h_393 _h_2751_4-SIK3_14_3_3_family_cytoplasm_YWHAG_SIK3_1O_1act green _h_4225 (1) PDK1-_h_5021 PDK1-_h_5182 _h_4146-Cyclin_D1 Ikaros_gene-_h_1457 green _h_2097 (0) PI3K_p110_beta_p85_beta_1ina-_h_5051_50 PI3K_p110_beta_p85_beta_1ina-_h_2434_34 PI3K_p110_beta_p85_beta_1ina-_h_2434_24 PI3K_p110_beta_p85_beta_1ina-_h_5051_4 PI3K_p110_beta_p85_beta_1ina-_h_5051_48 PI3K_p110_beta_p85_beta_1ina-_h_5051_8 PI3K_p110_beta_p85_beta_1ina-_h_2434_63 PI3K_p110_beta_p85_beta_1ina-_h_2434_57 PI3K_p110_beta_p85_beta_1ina-_h_5051_36 PI3K_p110_beta_p85_beta_1ina-_h_5051_23 PI3K_p110_beta_p85_beta_1ina-_h_5051_10 PI3K_p110_beta_p85_beta_1ina-_h_2434_68 PI3K_p110_beta_p85_beta_1ina-_h_5051_28 PI3K_p110_beta_p85_beta_1ina-_h_2434_74 PI3K_p110_beta_p85_beta_1ina-_h_2434_64 PI3K_p110_beta_p85_beta_1ina-_h_2434_71 PI3K_p110_beta_p85_beta_1ina-_h_2434_16 PI3K_p110_beta_p85_beta_1ina-_h_5051_13 Hck_cytoplasm-_h_3130_1 _h_4147-Fra2_JUN_1act_nucleus_v2 grey _h_6387 (0) grey _h_4991 (0) grey _h_2216_1 (0) grey _h_2216_2 (0) _h_159-NuRD_MBD2_Complex__MeCP1__nucleus green _h_3489 (0) green _h_4734 (0) green _h_4066 (1) grey _h_6294 (0) green _h_4677 (0) green _h_650 (2) green _h_4998 (0) green _h_1774 (0) grey _h_6341_3 (0) FOXO4_nucleus-_h_2472 green _h_2000 (0) grey _h_4076_6 (0) grey _h_4076_5 (0) grey _h_4076_4 (0) grey _h_4076_3 (0) FOXO4_nucleus-_h_2480 grey _h_4076_1 (0) grey _h_4076_2 (0) FOXO4_nucleus-_h_2381_1 green _h_4303 (0) green _h_57 (0) _h_3857 green _h_6051 (0) grey _h_5953 (0) grey _h_218 (0) grey _h_2265 (0) green _h_606 (0) grey _h_1401 (0) grey _h_2264_1 (0) E_cadherin_Ca2__beta_catenin_alpha_catenin_p120_catenin_cell_cell_junction_v1-_h_578 grey _h_3263_36 (0) grey _h_3263_37 (0) grey _h_3263_34 (0) grey _h_3263_35 (0) grey _h_3263_32 (0) grey _h_3263_33 (0) grey _h_3263_30 (0) grey _h_3263_31 (0) grey _h_3263_38 (0) grey _h_3263_39 (0) green _h_5709 (0) green _h_1982 (0) green _h_3997 (0) green _h_2643 (0) green _h_563 (1) grey _h_3263_25 (0) grey _h_3263_24 (0) grey _h_3263_27 (0) grey _h_3263_26 (0) grey _h_3263_21 (0) grey _h_3263_20 (0) grey _h_3263_23 (0) grey _h_3263_22 (0) grey _h_3263_29 (0) grey _h_3263_28 (0) green _h_275 (0) grey _h_3263_8 (0) grey _h_3263_9 (0) grey _h_3263_6 (0) grey _h_3263_7 (0) grey _h_3263_4 (0) grey _h_3263_5 (0) grey _h_3263_2 (0) grey _h_3263_3 (0) grey _h_3263_1 (0) grey _h_3263_18 (0) grey _h_3263_19 (0) grey _h_3263_10 (0) grey _h_3263_11 (0) grey _h_3263_12 (0) grey _h_3263_13 (0) grey _h_3263_14 (0) grey _h_3263_15 (0) grey _h_3263_16 (0) grey _h_3263_17 (0) green _h_4634 (0) E_cadherin_Ca2__beta_catenin_alpha_catenin_p120_catenin_cell_cell_junction_v1-_h_5057 green _h_3572 (0) E_cadherin_Ca2__beta_catenin_alpha_catenin_p120_catenin_cell_cell_junction_v1-_h_1114 green _h_815 (0) grey _h_3663 (0) E_cadherin_Ca2__beta_catenin_alpha_catenin_p120_catenin_cell_cell_junction_v1-_h_1273 green _h_4451 (0) grey _h_3263_78 (0) grey _h_3263_79 (0) grey _h_3263_72 (0) grey _h_3263_73 (0) grey _h_3263_70 (0) grey _h_3263_71 (0) grey _h_3263_76 (0) grey _h_3263_77 (0) grey _h_3263_74 (0) grey _h_3263_75 (0) grey _h_3263_48 (0) grey _h_3263_81 (0) grey _h_3263_80 (0) green _h_204 (0) grey _h_3263_69 (0) grey _h_3263_68 (0) grey _h_3263_61 (0) grey _h_3263_60 (0) grey _h_3263_63 (0) grey _h_3263_62 (0) grey _h_3263_65 (0) grey _h_3263_64 (0) grey _h_3263_67 (0) grey _h_3263_66 (0) green _h_3885 (0) E_cadherin_Ca2__beta_catenin_alpha_catenin_p120_catenin_cell_cell_junction_v1-_h_4583 red _h_989 (0) green _h_2457 (0) E_cadherin_Ca2__beta_catenin_alpha_catenin_p120_catenin_cell_cell_junction_v1-_h_1483 grey _h_3263_58 (0) grey _h_3263_59 (0) green _h_3067 (0) grey _h_3263_54 (0) grey _h_3263_55 (0) grey _h_3263_56 (0) grey _h_3263_57 (0) grey _h_3263_50 (0) grey _h_3263_51 (0) grey _h_3263_52 (0) grey _h_3263_53 (0) grey _h_3108 (0) green _h_1718 (0) red _h_3342 (0) green _h_4905 (1) red _h_4983 (0) grey _h_3263_43 (0) grey _h_3263_42 (0) grey _h_3263_41 (0) grey _h_3263_40 (0) grey _h_3263_47 (0) grey _h_3263_46 (0) grey _h_3263_45 (0) grey _h_3263_44 (0) grey _h_3263_49 (0) E_cadherin_Ca2__beta_catenin_alpha_catenin_p120_catenin_cell_cell_junction_v1-_h_4237 grey _h_865 (0) green _h_2516 (0) _h_62 E_cadherin_Ca2__beta_catenin_alpha_catenin_p120_catenin_cell_cell_junction_v2-_h_2592 _h_62 _h_62 green _h_1510 (1) _h_2347-Dicer _h_2344-SMAD5_SKI_1ina_cytoplasm green _h_2071 (2) _h_2342-LIMK1_1O _h_2343-alphav_beta3_Integrin_Fibrinogen_integral_to_membrane _h_2340-SIK1_1O_1act_cytoplasm _h_5051_2-PI3K_p110_delta_p55_gamma_1act_plasma_membrane _h_354-E2_ER_alpha__dimer__PELP1_Src_1act_caveola_v1 eNOS_cytoplasm-_h_4293 _h_2348-ERA_MTA1_HDAC1_LMO4_nucleus _h_4004 grey _h_4253 (0) red _h_4652 (1) grey _h_2169 (0) _h_1524-ASAP2_amphiphysin_II_plasma_membrane grey _h_889 (0) _h_571-FRS2_family_active_1act _h_571-SHC_1act_3O _h_1251-E_cadherin_Ca2__beta_catenin_gamma_catenin_alpha_catenin_p120_catenin_cell_cell_junction_v2 green _h_3235 (20) green _h_3786 (1) PIM1_gene-_h_5472 PIM1_gene-_h_4849 PIM1_gene-_h_3676 grey _h_1830_2 (0) Src_cytoplasm-_h_3130_2 _h_1250-VAMP2_fragment_1_1ina _h_1250-VAMP2_fragment_2_1ina green _h_2002 (1) green _h_1568 (0) _h_3836-NECD_sDelta_1_cytoplasm _h_3835-KLK2 _h_3832-IGFBP1 _h_3830-IRAK_TRAF6_MEKK3_1act_integral_to_membrane grey _h_5158 (0) grey _h_885 (0) grey _h_1081 (1) grey _h_2961 (0) grey _h_4246 (0) green _h_2196 (0) grey _h_5132 (0) grey _h_1833 (0) grey _h_2130 (0) grey _h_1962 (0) grey _h_5763 (0) grey _h_5921 (0) red _h_5684 (0) grey _h_2408 (0) green _h_1097 (1) grey _h_3762 (0) grey _h_4379 (0) grey _h_3352 (0) grey _h_4113 (0) SMAD3_SMAD4_1act_nucleus-_h_2957 grey _h_3881 (0) grey _h_3220 (0) EBAG9_gene-_h_2931 EBAG9_gene-_h_4396 _h_1622-LDHA _h_3839-NOXA _h_3838-FOS_nucleus grey _h_5320 (0) _h_1991-eIF4A_1act _h_6326-alphaD_beta2_Integrin_VCAM1_integral_to_membrane ZEB1_gene-_h_6226 grey _h_3263_65 (0) grey _h_3263_11 (0) grey _h_3263_4 (0) grey _h_3263_2 (0) grey _h_3263_47 (0) grey _h_3263_59 (0) grey _h_3263_54 (0) grey _h_3263_29 (0) grey _h_3263_39 (0) GRB2_SOS1_GAB_family_GAB2_GRB2_SOS1-_h_5977_1 _h_2122-IRS1_4O _h_2123-IL4_extracellular_region _h_2120-Nephrin_NEPH1_beta_Arrestin2_integral_to_membrane _h_2121-LIMK2_1act _h_2126-TMEM126A _h_2684 _h_2124-PLCgamma1_1act_cytoplasm green _h_3568 (3) _h_2128-IL5_extracellular_region grey _h_178_1 (0) grey _h_178_3 (0) grey _h_178_2 (0) beta_APP-_h_2441 grey _h_5273 (0) _h_5383-BAK green _h_4145 (0) CysLT2_gene-_h_1169 _h_4194_1-TAPP1_plasma_membrane _h_5051_22-PI3K_delta_1act_plasma_membrane CDK2_Cyclin_E1_1act-_h_3960 grey _h_6229_3 (0) _h_6208-SGK1 _h_186_3-KLHL12_Cul3_DVL _h_3263_18-Ca2__v1 _h_3263_18-alpha_catenin_cytoplasm _h_3263_18-E_cadherin_beta_catenin_early_endosome_v2 _h_3263_18-FGFR1c_FGF4_early_endosome _h_3263_18-p120_catenin_cytoplasm _h_3263_19-Ca2__v1 _h_3263_19-FGFR1c_FGF6_early_endosome _h_3263_19-alpha_catenin_cytoplasm _h_3263_19-E_cadherin_beta_catenin_early_endosome_v2 _h_3263_19-p120_catenin_cytoplasm _h_4188-DLX6 green _h_6451 (1) grey _h_1212 (0) grey _h_2566 (0) grey _h_5284 (0) _h_6454-Cyclin_E green _h_3126 (0) _h_3263_10-Ca2__v1 _h_3263_10-FGFR1b_FGF10_early_endosome _h_3263_10-alpha_catenin_cytoplasm _h_3263_10-E_cadherin_beta_catenin_early_endosome_v2 _h_3263_10-p120_catenin_cytoplasm red _h_1888 (7) grey _h_5437 (0) _h_3263_12-Ca2__v1 _h_3263_12-alpha_catenin_cytoplasm _h_3263_12-p120_catenin_cytoplasm _h_3263_12-FGFR1b_FGF2_early_endosome _h_3263_12-E_cadherin_beta_catenin_early_endosome_v2 _h_3263_13-Ca2__v1 _h_3263_13-FGFR1c_FGF6_early_endosome _h_3263_13-alpha_catenin_cytoplasm _h_3263_13-E_cadherin_beta_catenin_early_endosome_v2 _h_3263_13-p120_catenin_cytoplasm _h_3263_14-Ca2__v1 _h_3263_14-FGFR1b_FGF3_early_endosome _h_3263_14-alpha_catenin_cytoplasm _h_3263_14-E_cadherin_beta_catenin_early_endosome_v2 _h_3263_14-p120_catenin_cytoplasm _h_4187-CCL26_extracellular_region grey _h_3995_2 (0) grey _h_3147 (0) grey _h_4341 (0) green _h_2794_2 (1) green _h_2794_1 (1) grey _h_5507 (0) grey _h_5592 (0) grey _h_5703_1 (0) grey _h_5703_2 (0) grey _h_968 (0) grey _h_1438 (0) grey _h_3669 (0) _h_5051_23-PI3K_beta_1act_plasma_membrane _h_6032-uPA_uPAR_alphaM_beta2_Integrin_integral_to_membrane _h_6446-TGFA IL8_cytoplasm_gene-_h_5368 IL8_cytoplasm_gene-_h_4522 IL8_cytoplasm_gene-_h_3548 grey _h_4401 (0) grey _h_2014 (0) TCR_delta_gene-_h_2015 grey _h_4318 (0) red _h_2373 (5) red _h_320 (5) _h_2811-GATA3_nucleus STIM1_intracellular-_h_6028 _h_1695-IP3 _h_1695-DAG_plasma_membrane grey _h_3107 (0) _h_1697-TCF1_beta_catenin_1act_nucleus _h_1697-TLE2_nucleus _h_1696-DLX6 _h_1691-Caspase_2s _h_1690-cIAP2_cytoplasm green _h_1626 (10) green _h_4288 (9) green _h_3952 (6) green _h_3363 (8) green _h_2450 (27) green _h_1476 (8) _h_1699-EGFR_dimer__1act_cell_cell_junction _h_69 grey _h_179 (0) SRF_gene-_h_4019 _h_3384-COL1A2 _h_4660_1-FGFR_FGF2_Syndecan_1 _h_4660_2-FGFR_FGF2_Syndecan_1 green _h_243 (0) green _h_563 (0) green _h_2214 (2) cortisol_GR_alpha__dimer__1ina_cytoplasm_v1-_h_2068 red _h_5746 (0) green _h_4111 (33) _h_4076_4-FOXO4_cytoplasm _h_4076_4-FOXO4_14_3_3_family_cytoplasm_YWHAB_FOXO4_1O_2O _h_5361-HNF6 grey _h_1342 (0) _h_5365-alphav_beta3_Integrin_JAM_A_integral_to_membrane _h_5367-ARF1_GTP_1act _h_5367-GDP_v1 _h_5366-CaMK_IV_1p_1act _h_5369-p300_nucleus _h_5369-HES1_GATA1_nucleus_v2 grey _h_4995 (0) green _h_3369_1 (0) green _h_5336 (0) green _h_3369_2 (0) grey _h_3615 (0) _h_6311-SFXN3 _h_6312-PI3K_1act_cell_cell_junction_v2 _h_6315-alpha4_beta1_Integrin_Factor_XIII_integral_to_membrane _h_6314-PDGF_PDGFRA_1act _h_6317-LRPAP1_LRP8 _h_1476-PKC_zeta_1act _h_6319-FOXO3A_5N_nucleus _h_1478-HGS_endosome _h_3686 grey _h_1164 (0) _h_2710-TRAP_1 _h_2710-SMAD2_SMAD2_SMAD4_1act_cytoplasm _h_1424-MEK2_2O_1act _h_1424-MEK1_2O_1act _h_1506-p53_1O_1act VEGFR2__dimer__VEGFA__dimer__1act_integral_to_membrane_v4-_h_5772 grey _h_5314 (0) Rac1b_GDP_1ina-_h_2908 Fer-_h_3390 green _h_1723 (0) Fer-_h_1576 Fes-_h_4437 grey _h_2511 (0) green _h_5367 (0) PTPRK_gene-_h_1669 green _h_874 (17) _h_807_20-PI3K_p110_alpha_p85_beta_1act_plasma_membrane green _h_5009 (0) green _h_6010 (1) _h_3381-netrin_1_DCC_UNC5B_1act_integral_to_membrane _h_2716-MHF2 _h_5051_28-PI3K_p110_beta_p55_gamma_1act_plasma_membrane _h_5903-VEGFR2__dimer__VEGFA__dimer__NRP2_1act_integral_to_membrane grey _h_4760 (0) grey _h_2763 (0) grey _h_4322 (0) grey _h_998 (0) grey _h_5600 (0) green _h_4479 (0) _h_4269-FOXM1C_SP1_1act_nucleus grey _h_3288 (0) FOXO1_14_3_3_family_nucleus_v1_FOXO1_1O_4O_14_3_3_E-_h_3895_2 _h_4268-NDEL1_TACC3_centrosome _h_5842 STAT3_2O_cytoplasm-_h_196 TH_v2_gene-_h_5570 TH_v2_gene-_h_6017 TH_v2_gene-_h_1158 red _h_1043_1 (1) red _h_1043_2 (1) red _h_1043_3 (1) red _h_1043_4 (1) red _h_1043_5 (1) red _h_1043_6 (1) red _h_1043_7 (1) red _h_1043_8 (1) _h_5750-HMGB1_TLR2_TLR1_1act_integral_to_membrane grey _h_5912 (0) _h_5753-p70S6K_1act_1p _h_5754-IFNB _h_5755-SMAD1_SMURF2_1ina _h_5756-EPO_extracellular_region _h_5908-TRAIL_TRAILR2_FADD_TRADD_RIP_integral_to_membrane EMI1-_h_3159 _h_5759-HEY1_MYOD_nucleus _h_5759-TCF3_nucleus green _h_4519_2 (0) green _h_4519_1 (0) green _h_3789 (0) green _h_3224_1 (0) green _h_3224_2 (0) green _h_4059_2 (1) green _h_4059_1 (1) green _h_3993 (0) green _h_5402 (0) green _h_3185 (0) green _h_369 (0) grey _h_3070 (0) green _h_5136 (0) green _h_5104 (0) grey _h_799 (0) WNT3A_LRP6_FZD5_integral_to_membrane-_h_5574 WNT3A_LRP6_FZD5_integral_to_membrane-_h_5545 green _h_2342 (0) _h_3481-CD40_CD40L__trimer__TRAF6_integral_to_membrane green _h_4111 (46) grey _h_381 (0) CDC25C_cytoplasm-_h_4399 CDC25C_cytoplasm-_h_281 _h_4325-N_cadherin_Ca2__p120_catenin_cell_cell_junction _h_4325-alpha_catenin_cytoplasm _h_4325-beta_catenin_1O_cytoplasm_v2 _h_1112-beta_catenin_AR_T_DHT_TIF2_1act_nucleus _h_1112-TCF4_nucleus _h_2642_1-FAK_Src_Yes_Fyn_alphav_beta5_Integrin_1act_focal_adhesion_beta5_Integrin_Src_1act_1O_FAK_6O_1act_alphav_Integrin grey _h_6262 (0) grey _h_5085 (0) CBL_b-_h_4531 _h_118_6-14_3_3_family_chibby_beta_catenin_nucleus_chibby_beta_catenin_YWHAG _h_118_5-14_3_3_family_chibby_beta_catenin_nucleus_chibby_beta_catenin_14_3_3_E _h_118_4-14_3_3_family_chibby_beta_catenin_nucleus_chibby_beta_catenin_YWHAQ grey _h_6272 (0) PRKACA-_h_2880 green _h_1941 (2) PRKACA-_h_3937 grey _h_5314 (0) grey _h_4521 (0) green _h_3687 (2) PRKACA-_h_2281_1 green _h_413 (0) green _h_5694 (0) green _h_2988 (2) PRKACA-_h_4351 _h_118_2-14_3_3_family_chibby_beta_catenin_nucleus_chibby_YWHAB_beta_catenin _h_118_1-14_3_3_family_chibby_beta_catenin_nucleus_chibby_beta_catenin_YWHAZ _h_5575-E_cadherin_beta_catenin _h_433-Myb_2s_nucleus _h_924-SDF1_CXCR4_VAV1_1act_cell_leading_edge _h_431-Sphingosine _h_926-HDAC4_ER_alpha_1ina_nucleus _h_437-IL17 _h_436-TERT _h_923-p38_beta_1O_1O_1act grey _h_2807 (0) green _h_5557 (0) green _h_575 (0) green _h_2508 (0) green _h_4532 (0) green _h_1381 (1) _h_766_1-MEK2_1act_cytoplasm grey _h_1462 (0) grey _h_4087 (0) grey _h_5635 (0) _h_695-CBL_5O_1act_cytoplasm _h_2944_36-FGFR1b_FGF2_nucleus grey _h_3312 (0) grey _h_2374 (0) grey _h_6203 (0) _h_692-STAT6__dimer__ETS1_1act_nucleus _h_690-Lck_1O_1act _h_2944_39-FGFR1c_FGF2_nucleus _h_698-E2_ER_alpha__dimer__PELP1_Src_PI3K_1act_caveola grey _h_4761 (6) grey _h_4831 (4) grey _h_5031 (14) grey _h_2750 (7) HRAS_GDP_1ina_v1-_h_584 grey _h_5050 (0) green _h_1163 (0) red _h_559 (1) green 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NRIP1_gene-_h_1063 NRIP1_gene-_h_958 NRIP1_gene-_h_6277 green _h_499 (0) grey _h_1609 (0) grey _h_3462 (0) grey _h_1327 (0) grey _h_5246 (0) grey _h_2628 (0) grey _h_5599 (0) grey _h_4721 (0) grey _h_1788 (0) grey _h_4357 (0) grey _h_3735 (0) grey _h_2014 (0) grey _h_1515 (0) SHC_cytoplasm-_h_1775 SHC_cytoplasm-_h_4998 grey _h_6301 (0) _h_1107-IL2_extracellular_region _h_1106-phosphate _h_1106-RRas_GDP_1ina _h_6333-alpha2_beta1_Integrin_Laminin_5_integral_to_membrane RPA_ATR_ATRIP_RAD17_RFC2_5_9_1_1_TopBP1_CEP164_TIMELESS_TIPIN_CLASPIN_CHK1_1act_nucleus-_h_753 _h_549 _h_6332-DCP1B grey _h_5271 (0) red _h_2050 (1) red _h_4857 (0) _h_2235-HB_EGF_extracellular_region _h_4815 _h_4815 _h_4815 _h_4815 grey _h_2367 (0) grey _h_5283 (0) grey _h_6137 (0) green _h_858 (1) grey _h_810 (0) _h_1238_2 _h_1238_2 _h_1238_2 green _h_5151 (10) _h_334 _h_334 _h_334 _h_2794_2-BRAF_1act Receptors_internalized_by_Arf6_CIE-_h_3298 green _h_4200 (0) grey _h_967 (0) _h_1459-Neurotensin 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_h_5328-STAT3__dimer_non_phopshorylated__HDAC3_1act_nucleus _h_1435-Aurora_B_inner_kinetochore_of_condensed_chromosome _h_1434-RHOA_GTP_1act_trailing_edge _h_1434-GDP_v1 _h_6357-TXA2_TXA2_R_family_1act_integral_to_membrane _h_6357-GDP_v1 _h_6357-GNB1_GNG2_1act_cytoplasm _h_6357-G12_family_GTP_1act _h_1436-ATF2_p300 _h_6351-alpha5_beta1_Integrin_Fibrillin_1_integral_to_membrane _h_1430-MYC_Max_MIZ_1_DNMT3A_GFI1_nucleus _h_1433-STAT1__dimer__PIASy_1ina_nucleus _h_1432-AP1B1 _h_5899_51-PI3K_p110_alpha_p55_gamma_1act_plasma_membrane _h_1439-E2_ER_alpha__dimer__PELP1_1act_caveola _h_1438-TCR_CD3_MHC_I_CD8_1act_integral_to_membrane _h_5899_50-PI3K_p110_beta_p85_beta_1act_plasma_membrane KSR_14_3_3__dimer__MEK1_2_1ina_cytoplasm-_h_3092_1 KSR_14_3_3__dimer__MEK1_2_1ina_cytoplasm-_h_3092_2 KSR_14_3_3__dimer__MEK1_2_1ina_cytoplasm-_h_3092_3 KSR_14_3_3__dimer__MEK1_2_1ina_cytoplasm-_h_3092_4 KSR_14_3_3__dimer__MEK1_2_1ina_cytoplasm-_h_3092_5 KSR_14_3_3__dimer__MEK1_2_1ina_cytoplasm-_h_3092_6 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_h_4222-Aurora_A_TACC1_TRAP_chTOG_centrosome _h_1621_1-IL2_IL2R_alpha_beta_gamma_JAK1_LCK_JAK3_IRS1_2_1act_integral_to_membrane _h_253-IFN_gamma_extracellular_region _h_3080-NFAT1_CK1_alpha_1ina_cytoplasm green _h_1302 (0) _h_2044-DEP1_1act _h_3263_11-Ca2__v1 _h_3263_11-FGFR1c_FGF1_early_endosome _h_3263_11-alpha_catenin_cytoplasm _h_3263_11-E_cadherin_beta_catenin_early_endosome_v2 _h_3263_11-p120_catenin_cytoplasm _h_2047-Stathmin_2O _h_5051_41-PI3K_p110_alpha_p85_beta_1act_plasma_membrane green _h_1358 (1) _h_2041-FASLG_FAS__trimer__FADD_FADD_1act_integral_to_membrane grey _h_750 (0) _h_2901-PSA green _h_4801 (1) green _h_5783 (1) _h_4054-nectin_3_I_afadin_integral_to_membrane _h_963-CD4 _h_962-Gas2__cleaved_ _h_4050-eIF4A _h_964-HDAC5_BCL6_BCoR_nucleus _h_967-E2_ERA__dimer__POU4F2_1act_nucleus _h_4053-E4ICDs_ETO2_nucleus _h_968-Gq_family_GTP_1act _h_968-G_beta5_gamma2_1act _h_968-GDP_v1 _h_968-Gq_family_GTP_EBP50_1ina _h_968-TXA2_TP_alpha_1act_integral_to_membrane grey _h_5034 (0) red _h_6379 (0) _h_113-BRCA1 grey _h_560 (0) grey _h_4728 (0) green _h_6143 (1) _h_3840_3-CDK4_6_Cyclin_D_p16INK4a_v2_CDK4_6_1ina_p16INK4a_Cyclin_D1 _h_3840_2-CDK4_6_Cyclin_D_p16INK4a_v2_Cyclin_D3_CDK4_6_1ina_p16INK4a _h_3840_4-CDK4_6_Cyclin_D_p16INK4a_v2_Cyclin_D2_CDK4_6_1ina_p16INK4a _h_3840_6-CDK4_6_Cyclin_D_p16INK4a_v2_CDK4_6_1ina_p16INK4a_Cyclin_D1 _h_1061-MEK1_1O BRCA1_gene-_h_113 BRCA1_gene-_h_6180 green _h_5112 (0) green _h_330 (0) green _h_4819 (0) green _h_4743 (0) green _h_335 (138) green _h_821 (2) grey _h_3594 (0) grey _h_3353 (0) grey _h_159 (0) grey _h_523 (0) GRP1_cytoplasm-_h_4051 GRP1_cytoplasm-_h_5758_2 PI_4_P_synaptic_vesicle_membrane-_h_2700 grey _h_1768 (0) PEBPB2_gene-_h_2234 PEBPB2_gene-_h_6024 grey _h_5813 (0) MIR429_rna_gene-_h_5966 _h_1065-IPAF _h_3474 TMEFF2_gene-_h_4383 green _h_154 (1) beta2_Integrin_gene-_h_4795 _h_2681_3-NFAT1_c_4__dimer__EGR1_NFATc_1act_nucleus_EGR1_nucleus _h_2681_2-NFAT1_c_4__dimer__EGR1_NFAT1_1O_7O_2s_1act_nucleus_EGR1_nucleus green _h_3069 (2) green _h_896 (0) MIR26B_rna_gene-_h_1499 grey _h_3088 (0) _h_3263_15-Ca2__v1 _h_3263_15-alpha_catenin_cytoplasm _h_3263_15-E_cadherin_beta_catenin_early_endosome_v2 _h_3263_15-FGFR1c_FGF4_early_endosome _h_3263_15-p120_catenin_cytoplasm _h_5199_1-JUN_JUN_FOS_RACO_1_1act_nucleus_JUN_RACO_1_FOS grey _h_3729 (0) grey _h_5157 (0) NDUFV3_gene-_h_4251 NDUFV3_gene-_h_268 _h_385-Jak2_1act _h_2894_10-FOXO1_3a_4_14_3_3_family_1ina_cytoplasm_FOXO1_3a_4_inactive_1ina_YWHAS _h_2894_13-FOXO1_3a_4_14_3_3_family_1ina_cytoplasm_FOXO1_3a_4_inactive_1ina_YWHAS _h_2894_15-FOXO1_3a_4_14_3_3_family_1ina_cytoplasm_YWHAG_FOXO1_3a_4_inactive_1ina p15INK4b_gene-_h_816 p15INK4b_gene-_h_30 p15INK4b_gene-_h_2098 green _h_5585 (0) green _h_4038 (0) _h_382-Glucocorticoid_receptor_Hsp90_HDAC6_cytoplasm grey _h_1859 (0) grey _h_5273 (0) green _h_606 (1) red _h_4816 (0) red _h_2878 (0) grey _h_3753 (0) red _h_6460 (0) grey _h_1926 (0) grey _h_6243 (0) grey _h_1541 (0) grey _h_2793 (0) grey _h_5526 (0) _h_4449-GAB2_PI3K_Class_IA_SHP2 _h_4448-IL1_beta_fragment_IL1R1_IL1RAP_MYD88_1act_integral_to_membrane _h_389-BMX_1act_1O_cytoplasm green _h_640 (0) _h_3263_16-Ca2__v1 _h_3263_16-FGFR1b_FGF3_early_endosome _h_3263_16-alpha_catenin_cytoplasm _h_3263_16-E_cadherin_beta_catenin_early_endosome_v2 _h_3263_16-p120_catenin_cytoplasm _h_2434_31-PI3K_p110_delta_p55_gamma_1act_plasma_membrane _h_5736-KU_nucleus _h_4422-ERK5_1act_plasma_membrane _h_2434_35-PI3K_p110_delta_p85_beta_1act_plasma_membrane red _h_6403_1 (10) red _h_6403_2 (10) red _h_6320 (1) _h_2434_37-PI3K_p110_beta_p85_beta_1act_plasma_membrane Probasin_gene-_h_915 _h_2434_39-PI3K_p110_delta_p85_beta_1act_plasma_membrane _h_2434_38-PI3K_1act_plasma_membrane_v2 green _h_2020 (0) LNK_plasma_membrane-_h_886 red _h_1989 (1) green _h_671 (0) grey _h_4727 (0) GLI1_1act_nucleus-_h_531 green _h_3901 (0) green _h_108 (1) RAF1_1O_cytoplasm-_h_3264 _h_3263_17-Ca2__v1 _h_3263_17-alpha_catenin_cytoplasm _h_3263_17-FGFR1c_FGF2_early_endosome _h_3263_17-p120_catenin_cytoplasm _h_3263_17-E_cadherin_beta_catenin_early_endosome_v2 GAA_gene-_h_4049 PYK2_p130Cas-_h_5646 _h_5730-E2_ERA__dimer__PDI_1act_nucleus green _h_1611_2 (0) green _h_1611_1 (0) grey _h_3367 (0) grey _h_1516 (0) PI3K_p110_alpha_p85_beta_cytoplasm-_h_5899_25 PI3K_p110_alpha_p85_beta_cytoplasm-_h_5899_20 PI3K_p110_alpha_p85_beta_cytoplasm-_h_5899_14 PI3K_p110_alpha_p85_beta_cytoplasm-_h_5899_19 PI3K_p110_alpha_p85_beta_cytoplasm-_h_5899_29 PI3K_p110_alpha_p85_beta_cytoplasm-_h_5899_75 PI3K_p110_alpha_p85_beta_cytoplasm-_h_5899_48 PI3K_p110_alpha_p85_beta_cytoplasm-_h_5899_31 PI3K_p110_alpha_p85_beta_cytoplasm-_h_5899_80 green _h_6063 (0) grey _h_1439 (0) grey _h_1662 (0) _h_2907-MYOD_1act_3N grey _h_2552_2 (0) grey _h_4561_2 (0) red _h_3913 (1) red _h_2110 (0) _h_119-beta_catenin_cytoplasm _h_119-Axin1_APC_GSK3_beta_catenin_cytoplasm_v1 grey _h_3037 (0) NDRG2_gene-_h_3437 green _h_3235 (3) Cyclin_K_gene-_h_703 green _h_3235 (19) grey _h_1299 (0) grey _h_5547 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grey _h_350 (0) grey _h_5755 (0) green _h_38 (0) grey _h_5225 (0) grey _h_1495 (0) _h_4277-p190B_1act_plasma_membrane grey _h_321 (0) _h_1617-PDGF_CC_PDGFRA__dimer__1act_integral_to_membrane grey _h_625 (0) grey _h_3660 (0) grey _h_3120 (0) grey _h_5442 (0) grey _h_629 (0) grey _h_1886 (0) grey _h_2482 (0) grey _h_2833 (0) _h_5068-PKC_beta2_1act_plasma_membrane _h_2704-GLI2A_1act_nucleus _h_5665_2-SHBG_T_DHT_integral_to_membrane _h_5665_1-SHBG_T_DHT_integral_to_membrane _h_5918-IL18R_integral_to_membrane green _h_445 (1) _h_5548-CENTA1_KIF3B_plasma_membrane grey _h_5652 (0) PKC_delta_1O_1act_1O_1O_plasma_membrane-_h_6097 _h_5919-BIM _h_109-40S_S6_ribosomal_protein__40s_Ribosomal_subunit_eIF3_v1 _h_807_38-PI3K_p110_beta_p85_beta_1act_plasma_membrane _h_5917-RB1_E2F4_DP_CtBP_nucleus _h_3455_3-NFAT1_c_4_YWHAQ_1ina_cytoplasm_NFAT4_1ina_1p_cytoplasm_YWHAQ grey _h_5347 (0) green _h_4605 (1) _h_2701-Myb_Cbp_nucleus 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_h_6104 (0) green _h_5606 (0) grey _h_5798 (0) _h_1610-proenkephalin TRAILR2_gene-_h_1783 _h_844 green _h_505 (5) grey _h_4220 (0) _h_3285-STAT1__dimer__1ina_cytoplasm red _h_2958 (0) grey _h_5584 (0) grey _h_3602 (0) grey _h_1278 (0) grey _h_900 (0) grey _h_2695 (0) grey _h_4108 (0) grey _h_3409 (0) grey _h_2831 (0) grey _h_3780 (0) green _h_3452 (0) green _h_3605 (1) grey _h_2850 (0) grey _h_5141 (0) green _h_1956 (1) grey _h_6127 (0) grey _h_1536 (0) Nucleolin_gene-_h_546 red _h_3929 (2) green _h_5116 (0) green _h_1269 (0) green _h_1204 (0) green _h_763 (1) green _h_5030 (8) green _h_2190 (0) green _h_2805 (0) green _h_4128 (0) green _h_2202 (0) green _h_2323 (0) green _h_4148 (0) green _h_5980 (0) green _h_4982 (1) green _h_320 (8) green _h_253 (0) green _h_2420 (0) green _h_4378 (8) green _h_4468 (1) green _h_248 (1) green _h_3313 (6) green _h_3268 (6) green _h_5511 (2) green _h_2953 (0) green _h_6402 (0) green _h_6423 (0) green _h_5403 (0) green _h_6406 (0) green _h_6136 (0) green _h_4959 (0) green _h_1683 (0) green _h_1745 (0) green _h_2373 (8) _h_6399-SIRT1_PGC1A_nucleus grey _h_5855 (0) grey _h_1153 (0) grey _h_2529 (0) _h_5128-alpha4_beta1_Integrin_Fibronectin_Paxillin_trailing_edge green _h_3475_1 (0) green _h_3475_3 (0) green _h_3475_2 (0) _h_2394 GMCSF_GMR_alpha_CSF2RB_JAK2__dimer__integral_to_membrane-_h_271 grey _h_6475 (0) grey _h_3631 (0) green _h_3590 (2) _h_4667-NDEL1_Katanin_60_Dynein_heavy_chain _h_4469-PIG3 _h_4468-IL4_extracellular_region _h_4465-Telomerase_hnRNP_C1_C2 _h_2434_12-PI3K_p110_alpha_p55_gamma_1act_plasma_membrane _h_4467-Sema3e_Plexin_D1_Nrp1_integral_to_membrane _h_4466-Aurora_A_BRCA1 grey _h_2001 (1) green _h_4342 (0) grey _h_3822 (0) grey _h_3896 (0) _h_4462-VAV2_1act Nezha-_h_1394 green _h_701 (24) green _h_4111 (37) PLCgamma1-_h_2428 PLCgamma1-_h_1338 PLCgamma1-_h_2460 grey _h_6104 (0) grey _h_4808_4 (0) grey _h_4808_2 (0) grey _h_4808_3 (0) PLCgamma1-_h_5949 grey _h_5606 (0) PLCgamma1-_h_2423 grey _h_4808_1 (0) 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grey _h_741 (0) red _h_4535 (0) red _h_2405 (0) red _h_3974 (0) BCL2-_h_1865 _h_5201-IGF_1R_heterotetramer_IGF1_IRS_Nck grey _h_3166 (0) _h_5894-NEMO_ATM_nucleus green _h_2574 (0) _h_482-TAp63a__tetramer__1ina_nucleus_v1 _h_3263_37-Ca2__v1 _h_3263_37-FGFR1c_FGF6_early_endosome _h_3263_37-alpha_catenin_cytoplasm _h_3263_37-p120_catenin_cytoplasm _h_3263_37-E_cadherin_beta_catenin_early_endosome_v2 HSP70_1A_gene-_h_5795 HSP70_1A_gene-_h_6201 grey _h_1651 (0) grey _h_3810 (6) grey _h_5404 (0) green _h_4604 (0) green _h_5478 (0) green _h_6432 (0) green _h_1494 (0) GLI1_nucleus-_h_3142 GLI1_nucleus-_h_6020_2 _h_4547-MDM2 E_cadherin_Ca2__gamma_catenin_alpha_catenin_p120_catenin_cell_cell_junction-_h_3439 HGF_dimer__MET_dimer__1act_endosome-_h_4686 _h_4544-FAK_3O_1act green _h_2524 (3) grey _h_6411 (0) grey _h_240 (0) grey _h_3995_4 (0) grey _h_3995_2 (0) grey _h_3995_3 (0) grey _h_3995_1 (0) _h_4545-Fyn_1O_1act grey _h_530 (0) grey _h_1490 (0) green _h_4889 (2) _h_5207-MIR34A_rna green 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_h_5058-TCF4E green _h_3554 (0) grey _h_2078 (0) grey _h_5810 (0) grey _h_3597 (0) Aurora_A-_h_4915 grey _h_4334 (0) green _h_1977 (0) green _h_4268 (0) grey _h_4124 (0) Aurora_A-_h_3256 green _h_676 (0) grey _h_3143 (0) Aurora_A-_h_4030 green _h_3034 (1) green _h_526 (0) green _h_2835 (0) grey _h_4466 (0) grey _h_2514 (0) grey _h_4222 (0) grey _h_2161 (0) grey _h_1056 (0) grey _h_43 (0) grey _h_2813 (0) grey _h_3315 (0) grey _h_3402 (0) grey _h_305 (0) Aurora_B-_h_1435 green _h_5011 (0) green _h_5629 (0) grey _h_4286 (0) grey _h_305 (0) green _h_4163 (0) grey _h_1228 (0) grey _h_5702 (0) grey _h_3402 (0) green _h_6310 (0) green _h_6256 (0) grey _h_1030 (0) grey _h_5972 (0) green _h_5820 (0) green _h_1513 (0) green _h_1657 (0) _h_807_2-PI3K_p110_delta_p85_beta_1act_plasma_membrane _h_807_3-PI3K_p110_delta_p85_beta_1act_plasma_membrane green _h_1109 (0) _h_5137-RPS27L _h_1619-SPHK1_1act_plasma_membrane grey _h_2468 (0) _h_1967-ELK1_SRF_1act_nucleus_v2 _h_1547 _h_1965-SHC_Grb2_SOS1_1act_v1 green _h_5259 (0) green _h_5626 (5) green _h_2465 (0) grey _h_453 (0) B_cell_antigen_BCR_complex_LYN_v2-_h_908 _h_1962-SMAD3_SMAD4_TFE3_1act_nucleus _h_1613-OPRM1 green _h_2526 (0) green _h_886 (0) green _h_4300 (0) green _h_1546 (0) green _h_6421 (0) green _h_1131 (0) green _h_1709 (0) green _h_3496 (0) green _h_5588 (0) green _h_6111 (0) green _h_3330 (0) green _h_257 (0) green _h_3386 (0) green _h_5446 (0) green _h_273 (0) green _h_1905 (0) green _h_3408 (0) _h_4-ANF _h_5-IL3_IL3RA_CSF2RB__hexamer__integral_to_membrane _h_6-MAD2 _h_7-Akt1_1O_1O_1act_plasma_membrane _h_1-p27Kip1 _h_3-p38_alpha_1act_1O _h_5133-LEF1_beta_catenin_PITX2_1act_nucleus _h_8-PDK1_CARD11_BCL10_MALT1_TRAF6_1act _h_9-C3G_1act_cell_cell_junction _h_3933-Arf6_GTP_1act_cell_cell_junction _h_3933-GDP_v1 _h_3092_5-14_3_3_E _h_3092_5-KSR_14_3_3__MEK1_2_1ina_cytoplasm_14_3_3_E_KSR_1O_MEK1_2_1ina green _h_1930 (0) _h_2708-RXR_alpha_1O_3O _h_2709-BPAG1e _h_2706-Ephrin_B1_EPHB3 _h_2707-IL3_IL3RA_CSF2RB__dodecamer__JAK2_JAK2_SHP2_1act_integral_to_membrane _h_1370_2-Cbp_p300_SKP2 RAF1_plasma_membrane-_h_4800 green _h_6066 (0) green _h_5560 (0) green _h_1713 (0) green _h_1133 (0) green _h_4675 (0) _h_2703-TRAF6_MEKK3_1act _h_2700-PI_4_5_P2_synaptic_vesicle_membrane grey _h_6200 (0) _h_2432-TUBA1A _h_1739-ErbB2_ErbB3_neuregulin_1_beta_1act_integral_to_membrane_v4 _h_2864-MEK1_3O_2O_1act_cytoplasm _h_2864-MEK2_1act_cytoplasm green _h_335 (155) green _h_2318 (0) NIK_1act_cytoplasm-_h_5781 green _h_504 (0) _h_4661-STX1A_SNAP25_fragment_1_VAMP2_1act _h_4661-STX1A_SNAP25_VAMP2_1act green _h_3146 (0) GDI1-_h_61 grey _h_3125 (0) green _h_592 (0) green _h_1995 (0) green _h_6485 (0) green _h_546 (2) green _h_4999 (0) green _h_4843 (0) _h_6398-GLUT3 green _h_5047 (0) _h_2139_3 _h_6391-ROCK1_1act_phagocytic_vesicle _h_6391-MYHC2A_phagocytic_vesicle _h_1383-Nephrin_NEPH1_Par3_Par6_Atypical_PKCs_cell_cell_junction _h_6393-IL2R_gamma_cytokines_IL2R_gamma_1act_integral_to_membrane _h_2132-LPA_LPA1 _h_6395-Exocyst_plasma_membrane _h_4856-Estrogen_receptor_alpha _h_6396-BID green _h_2494 (0) _h_6104-LAT_PLCgamma1_GRB2_SLP76_GADs CHRNE_nucleus_gene-_h_5638 red _h_3510 (1) red _h_4440 (0) red _h_3089 (1) _h_6105-PRL_1 grey _h_5358 (0) _h_1888-AP1_1act_nucleus green _h_1149 (0) _h_1730-PML KRT19-_h_414 _h_6100-NGF__dimer__TRKA_1act_endosome _h_4857-Exo70_SEPT2_IQGAP1 grey _h_4493_4 (0) grey _h_4493_5 (0) grey _h_4493_6 (0) grey _h_4493_1 (0) grey _h_4493_2 (0) grey _h_4493_3 (0) _h_1737-FAK_1O_1O_1act_cytoplasm green _h_25 (0) red _h_3495 (0) red _h_1034 (0) green _h_3838 (0) green _h_111 (0) green _h_3715 (0) _h_2698-PSA FANCD2_FANCI-_h_490 _h_1887-alpha6_beta4_Integrin_Laminin_4_integral_to_membrane green _h_1211 (2) green _h_4009 (1) grey _h_5312 (0) grey _h_790 (0) SPATA18_gene-_h_5215 NUR77_gene-_h_2721 green _h_3952 (3) _h_2874_4-FAK_Src_Yes_Fyn_Paxillin_PAK1_betaPIX_PKL_NCK1_2_1act_cytoplasm_FAK_6O_PAK1_1act_PKL_1act_3O_Src_1act_1O_paxillin_2O_NCK2_betaPIX_1act green _h_3141 (1) green _h_6129 (0) _h_4851-ErbB4_ErbB4_neuregulin_2_beta_neuregulin_2_beta_1act_integral_to_membrane grey _h_663_1 (0) green _h_4129 (22) green _h_4656 (0) green _h_569 (1) grey _h_1055 (0) grey _h_5188 (0) green _h_849 (0) green _h_2412 (0) green _h_3440 (0) grey _h_3990 (0) green _h_1372 (2) green _h_515_1 (2) grey _h_5932 (0) green _h_515_6 (2) green _h_515_4 (2) green _h_515_5 (2) grey _h_1621_2 (0) green _h_515_3 (2) green _h_515_2 (2) grey _h_1621_1 (0) grey _h_3779 (0) green _h_3069 (0) green _h_1262 (0) _h_2874_3-FAK_Src_Yes_Fyn_Paxillin_PAK1_betaPIX_PKL_NCK1_2_1act_cytoplasm_FAK_6O_PAK1_1act_PKL_1act_3O_paxillin_2O_NCK2_betaPIX_1act_Fyn_1O_1act _h_4018-Ephrin_A5_EPHB2_1act_integral_to_membrane _h_4019-SRF _h_1353-p21CIP1 _h_1036_98-alpha10_beta1_Integrin_endosome RKIP_RAF1-_h_5443 _h_4013-mTORC1_ULK1_2_ATG13_FIP200 _h_4014-PP1_C_PP_1G _h_4016-MRCK_1O_2O_1act _h_4017-Ca2__growth_cone _h_3092_1-YWHAG _h_3092_1-KSR_14_3_3__MEK1_2_1ina_cytoplasm_YWHAG_KSR_1O_MEK1_2_1ina _h_3092_2-KSR_14_3_3__MEK1_2_1ina_cytoplasm_YWHAZ_KSR_1O_MEK1_2_1ina _h_3092_2-YWHAZ _h_3092_3-KSR_14_3_3__MEK1_2_1ina_cytoplasm_YWHAQ_KSR_1O_MEK1_2_1ina _h_3092_3-YWHAQ _h_3092_4-KSR_14_3_3__MEK1_2_1ina_cytoplasm_YWHAB_KSR_1O_MEK1_2_1ina _h_3092_4-YWHAB FOXO1_14_3_3_family_nucleus_v2_YWHAS_FOXO1_1O_2O-_h_2760_5 _h_3092_6-YWHAS _h_3092_6-KSR_14_3_3__MEK1_2_1ina_cytoplasm_KSR_1O_YWHAS_MEK1_2_1ina Sphingosine_plasma_membrane-_h_4626 grey _h_4886_2 (0) grey _h_4886_3 (0) grey _h_4886_1 (0) _h_3015-p130Cas_CRK_Src_PYK2_1act grey _h_3546 (0) green _h_580 (1) green _h_24 (1) _h_3014-RB1 _h_3975 green _h_380_2 (12) green _h_380_3 (12) green _h_380_1 (12) green _h_380_6 (12) green _h_380_4 (12) green _h_380_5 (12) grey _h_798 (0) _h_2805-IL8_extracellular_region Plasmin_cytoplasm-_h_2622 grey _h_2286 (0) grey _h_180 (0) grey _h_2831 (0) _h_1638-beta4_integrin grey _h_1320 (0) grey _h_670 (0) grey _h_2558 (0) green _h_754_1 (0) green _h_754_2 (0) green _h_3373_1 (0) green _h_3373_2 (0) green _h_786 (0) grey _h_4080 (0) _h_2647-Progesterone_Receptor_1ina S1P1_gene-_h_4249 _h_4190-PLK1 grey _h_5036 (0) grey _h_3766 (0) _h_2434_79-PI3K_p110_delta_p55_gamma_1act_plasma_membrane _h_2434_78-PI3K_p110_beta_p55_gamma_1act_plasma_membrane _h_2434_75-PI3K_p110_beta_p85_beta_1act_plasma_membrane _h_2434_74-PI3K_p110_delta_p55_gamma_1act_plasma_membrane _h_2434_77-PI3K_p110_beta_p85_beta_1act_plasma_membrane _h_2434_71-PI3K_1act_plasma_membrane_v2 _h_2434_70-PI3K_beta_1act_plasma_membrane _h_2434_73-PI3K_delta_1act_plasma_membrane _h_3546-mTORC1_PGC1A_YY1_1act_nucleus _h_3545-Myb_GATA1_nucleus DEC2_gene-_h_5776 green _h_5974 (2) decorin_gene-_h_509 _h_3263_24-Ca2__v1 _h_3263_24-alpha_catenin_cytoplasm _h_3263_24-FGFR1b_FGF1_early_endosome _h_3263_24-E_cadherin_beta_catenin_early_endosome_v2 _h_3263_24-p120_catenin_cytoplasm _h_1594-TRAIL_TRAILR1_DAP3_GTP_FADD_integral_to_membrane _h_3549-PUMA _h_3548-IL8_cytoplasm grey _h_1857 (0) green _h_1128 (0) _h_2538-ERA_MRF1_nucleus _h_1853-CDK4 _h_3263_21-Ca2__v1 _h_3263_21-alpha_catenin_cytoplasm _h_3263_21-p120_catenin_cytoplasm _h_3263_21-FGFR1b_FGF2_early_endosome _h_3263_21-E_cadherin_beta_catenin_early_endosome_v2 green _h_3952 (12) _h_3263_20-Ca2__v1 _h_3263_20-alpha_catenin_cytoplasm _h_3263_20-E_cadherin_beta_catenin_early_endosome_v2 _h_3263_20-FGFR1c_FGF4_early_endosome _h_3263_20-p120_catenin_cytoplasm Condensin_I_complex_chromosome_v1-_h_6310 grey _h_3650_1 (0) grey _h_3650_2 (0) grey _h_3650_3 (0) grey _h_6283 (0) grey _h_2922 (0) grey _h_4880 (0) YWHAQ_gene-_h_5149 grey _h_6347 (0) grey _h_29_1 (0) grey _h_29_3 (0) grey _h_1889_1 (0) grey _h_966 (0) grey _h_2175_3 (0) grey _h_2175_2 (0) grey _h_4241 (1) grey _h_3567_3 (0) grey _h_3567_1 (0) green _h_4834 (0) grey _h_3338 (0) _h_520-KLRG1_1act _h_2564-SHH_Np_Cholesterol_BOC_1act_extracellular_region _h_2299-SKI_SIN3a_NCoR1_TIF1B_Myb_nucleus _h_1598-4E_BP1_1O_1act _h_5869-IL17F _h_5867-MMP9_extracellular_region _h_5864-Cyclin_A _h_5862-TCF4_beta_catenin_KLF4_1ina_nucleus NFAT4_1ina_1p_cytoplasm-_h_4001 NFAT4_1ina_1p_cytoplasm-_h_6163_2 _h_1036_63-alpha11_beta1_Integrin_endosome _h_1036_62-alphav_beta1_Integrin_endosome _h_1036_61-alpha10_beta1_Integrin_endosome grey _h_2213 (0) _h_1036_67-alpha11_beta1_Integrin_endosome _h_1036_66-alpha4_beta1_Integrin_endosome grey _h_5665_2 (0) green _h_1329 (2) green _h_6295 (1) red _h_3740 (0) grey _h_388_2 (0) green _h_4159 (0) green _h_3622 (0) red _h_5377 (0) green _h_4696_3 (0) green _h_4696_2 (0) green _h_4696_1 (0) grey _h_4943_2 (0) _h_1036_69-alpha11_beta1_Integrin_endosome _h_1036_68-alpha8_beta1_Integrin_endosome grey _h_5933 (0) _h_2312_2-SMAD2_3_SMAD4_MYC_Max_MIZ_1_nucleus_SMAD2_2O_1act_MYC_Max_SMAD4_MIZ_1 _h_3136-MMP9_1act_extracellular_region TERT_gene-_h_2540 TERT_gene-_h_5251 TERT_gene-_h_905 TERT_gene-_h_4507 TERT_gene-_h_1206 TERT_gene-_h_1127 TERT_gene-_h_1187 TERT_gene-_h_4744 TERT_gene-_h_3790 TERT_gene-_h_436 TERT_gene-_h_4487 TERT_gene-_h_5108 TERT_gene-_h_4117 TERT_gene-_h_2992 TERT_gene-_h_4353 TERT_gene-_h_4352 TERT_gene-_h_5814 green _h_1425 (3) green _h_6155 (0) grey _h_5394 (0) _h_528-TCR_CD3_MHC_II_CD4_LCK_1act_integral_to_membrane grey _h_4548_1 (0) green _h_1631 (0) _h_3138-p107 _h_3139-CABIN1_1act_1p red _h_3776 (3) red _h_515_6 (3) red _h_515_4 (3) red _h_515_5 (3) red _h_515_2 (3) red _h_515_3 (3) red _h_515_1 (3) green _h_4885 (0) _h_244_3 _h_244_3 _h_2693-Tie2_Ang2 PKA_C_alpha_cytoplasm-_h_1405 grey _h_5086 (0) grey _h_696 (0) _h_2355_2-SMAD2_3_SMAD4_ARC105_1act_nucleus_ARC105_Smad3_2O_1act_SMAD4 _h_2355_1-SMAD2_3_SMAD4_ARC105_1act_nucleus_ARC105_SMAD2_2O_1act_SMAD4 grey _h_4178_2 (0) green _h_2780 (0) grey _h_3908_2 (0) grey _h_2972 (0) SCC-__start__6 SCC-__start__7 SCC-__start__4 SCC-__start__5 SCC-__start__3 grey _h_3780 (0) grey _h_3452 (0) grey _h_4314 (0) grey _h_2930 (0) green _h_1956 (0) grey _h_1443 (0) SCC-__start__1 green _h_44 (0) _h_660_2-p38_beta_1O_1act_1O_nucleus green _h_5772 (0) red _h_5544 (10) SCC-__start__9 FCGR1_extracellular_region_gene-_h_1550 green _h_4828 (0) green _h_1180 (0) _h_3250_6-SIK1_14_3_3_family_cytoplasm_SIK1_1O_1act_14_3_3_E _h_4011_2-FGFR1_FGF_complex_Sef_endocytic_vesicle Ran_GTP_Exportin_1_HDAC1_nucleus-_h_5510 green _h_3836 (0) green _h_6304 (0) green _h_3610 (0) MIR17_rna_gene-_h_1811 grey _h_5202 (0) green _h_1026 (0) green _h_1094 (0) grey _h_4255 (0) NFATc_3O_nucleus-_h_845 grey _h_3722 (0) _h_6020_2-GLI1_1act_nucleus FGFR1b_FGF3_plasma_membrane-_h_2944_53 FGFR1b_FGF3_plasma_membrane-_h_2944_22 grey _h_4011_1 (0) FGFR1b_FGF3_plasma_membrane-_h_2944_44 FGFR1b_FGF3_plasma_membrane-_h_2944_21 green _h_3021 (7) FGFR1b_FGF3_plasma_membrane-_h_2944_29 grey _h_2003_9 (0) FGFR1b_FGF3_plasma_membrane-_h_2944_6 grey _h_1636_8 (0) FGFR1b_FGF3_plasma_membrane-_h_2944_14 FGFR1b_FGF3_plasma_membrane-_h_2944_2 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_h_1376-JNK_1O_1act_1O _h_4008-Axin1_APC__beta_catenin_cytoplasm grey _h_977 (0) grey _h_1301 (0) grey _h_3661 (0) grey _h_5081 (0) grey _h_4130 (0) grey _h_6282 (0) grey _h_276 (0) grey _h_6222 (0) grey _h_2746 (0) grey _h_2245 (0) grey _h_1295 (0) _h_4111-CDC42_GTP_1act_plasma_membrane _h_4111-GDP_v1 _h_5434-MAP4K4_1act green _h_6337_3 (0) green _h_6337_2 (0) green _h_6337_1 (0) _h_4839-RAF1_14_3_3_E red _h_4901 (1) _h_4833-GDP_v1 _h_4833-CXCL10_CXCR3_integral_to_membrane _h_4833-GNB1_GNG2_1act_cytoplasm _h_4833-CXCL13_CXCR3_integral_to_membrane _h_4833-GNAI2_GTP_1act_v1 _h_4867 _h_4831-GDP_v1 _h_4831-HRAS_GTP_1act_v1 _h_4836-HIF2A_ARNT_nucleus_v2 green _h_6403_1 (9) green _h_6403_2 (1) _h_4834-Akt1_1O_1act_1O_1O_plasma_membrane _h_4523-Insulin_Receptor_Insulin_IRS1_Shp2 green _h_1277 (2) green _h_505 (1) green _h_2450 (21) grey _h_707 (0) red _h_2574 (0) _h_5048-PDK1_1act_plasma_membrane BAD_BCL_XL-_h_1928 BAD_BCL_XL-_h_6364 BAD_BCL_XL-_h_6069 _h_598-VEGFR3_Type_I_Collagen_alpha1_beta1_Integrin_1act_plasma_membrane grey _h_2845 (0) _h_136-E2F1 _h_137-GLI1_nucleus grey _h_2286 (0) _h_135-PI3K_1act_plasma_membrane_v2 _h_132-Crk_p130_Cas _h_133-Dopamine_cytoplasm _h_130-IL27RA _h_131-EPS15_1O_plasma_membrane _h_4127-PER1_TIMELESS LDHA_gene-_h_1622 LDHA_gene-_h_183 _h_138-alpha6_beta1_Integrin_CD9 grey _h_6229_2 (0) _h_6272-GAB1_SHP2_PKA_eNOS _h_3994_4-PI3K_gamma_p101_1act_plasma_membrane _h_1500-DNA_TOP1_fragment_5 _h_1500-DNA_TOP1_fragment_4 _h_1500-DNA_TOP1_fragment_6 _h_5040-FGFR1_NCAM grey _h_1329 (2) _h_1503-BNIP3 _h_3994_2-PI3K_gamma_p84_1act_plasma_membrane _h_3263_77-Ca2__v1 _h_3263_77-alpha_catenin_cytoplasm _h_3263_77-FGFR1c_FGF2_early_endosome _h_3263_77-E_cadherin_beta_catenin_early_endosome_v2 _h_3263_77-p120_catenin_cytoplasm _h_5042-MDM2_2O_1act_nucleus CDK6_gene-_h_5818 CDK6_gene-_h_2105 _h_1504-RR2 green _h_5781 (0) _h_5354 _h_5715 green _h_2109 (0) grey _h_1490 (0) E4ICDs_1act_5O_cytoplasm-_h_5699 grey _h_1498 (0) green _h_2266 (0) grey _h_6239 (0) green _h_2900 (0) NR1D1_gene-_h_1712 grey _h_2581 (1) LPL_gene-_h_3109 _h_1609-EGFR_EGFR_EGF_EGF_p46_SHC_1act_endosome XBP1_gene-_h_464 XBP1_gene-_h_4052 green _h_4716 (0) HRAS_GTP_1act_plasma_membrane-_h_4283 green _h_135 (3) green _h_2095 (0) green _h_1114 (0) _h_2557-Ephrin_A5_EPHA3_4_5_6_7_1act grey _h_4932 (0) green _h_1860 (0) green _h_1856 (0) TNF_alpha_extracellular_region_gene-_h_4713 TNF_alpha_extracellular_region_gene-_h_3816 TNF_alpha_extracellular_region_gene-_h_3012 TNF_alpha_extracellular_region_gene-_h_3257 TNF_alpha_extracellular_region_gene-_h_5562 TNF_alpha_extracellular_region_gene-_h_5418 TNF_alpha_extracellular_region_gene-_h_6086 TNF_alpha_extracellular_region_gene-_h_5777 _h_1829-sTNF_alpha_TNFR1A_TRADD_RIP_TRAF2_1act_integral_to_membrane _h_1829-sTNF_alpha_TNFR1A_TRADD_STAT1__dimer__1act_integral_to_membrane _h_52-CaT1_1act_plasma_membrane _h_1827-Beta_Casein_extracellular_region _h_2554-MMP1 _h_1822-TGFB1_1act_extracellular_region _h_57-BCL6 _h_1820-uPA_cytoplasm _h_1821-alpha9_beta1_Integrin_VEGFD__dimer__integral_to_membrane _h_1602-IRF_8 _h_1603-CACNA1G green _h_4683_9 (4) green _h_4683_8 (4) green _h_584 (25) green _h_4683_5 (4) green _h_4683_4 (4) green _h_4683_7 (4) green _h_4683_6 (4) green _h_4683_1 (4) green _h_4683_3 (4) green _h_4683_2 (4) _h_5013-DLX5 _h_5012-RhoA_GDP_Rho_GDI_gamma_1ina _h_2894_14-FOXO1_3a_4_14_3_3_family_1ina_cytoplasm_FOXO1_3a_4_inactive_1ina_YWHAS _h_1977-CDC25B_1O_centrosome _h_5017-Tau_1act _h_5016-RALGDS_plasma_membrane _h_2290-HIV_1_Tat_SIRT1_1act_nucleus grey _h_3177_2 (0) grey _h_3177_1 (0) TH_v2-_h_3333 _h_5018-NOS2 _h_2295-COX_2 _h_2296-MEKK1_fragment_1 _h_2296-MEKK1_fragment_2 _h_1607-SHH_Np_Cholesterol_Hhip_1ina_integral_to_membrane _h_1923-TSC1_TSC2_IKK_beta_1ina _h_1922-c_FLIPS _h_1921-IL4_IL4R_JAK1_IL2R_gamma_JAK3_SHIP_1act_integral_to_membrane _h_205-PIG3 C3G_1ina-_h_9 _h_1925-ATF2_JUND_1act_nucleus _h_1929-Galectin_1 _h_1605-MDR1 PI3K_p110_beta_p85_beta_plasma_membrane-_h_807_78 PI3K_p110_beta_p85_beta_plasma_membrane-_h_807_33 PI3K_p110_beta_p85_beta_plasma_membrane-_h_807_46 PI3K_p110_beta_p85_beta_plasma_membrane-_h_807_63 PI3K_p110_beta_p85_beta_plasma_membrane-_h_807_65 PI3K_p110_beta_p85_beta_plasma_membrane-_h_807_27 PI3K_p110_beta_p85_beta_plasma_membrane-_h_807_19 PI3K_p110_beta_p85_beta_plasma_membrane-_h_807_59 PI3K_p110_beta_p85_beta_plasma_membrane-_h_807_43 _h_2875-AID _h_2894_17-FOXO1_3a_4_14_3_3_family_1ina_cytoplasm_YWHAB_FOXO1_3a_4_inactive_1ina _h_201_1-mTORC1_complex_14_3_3_family_1ina_Raptor_1ina_2O_PRAS40_YWHAG_GBL_mTOR green _h_4295 (4) green _h_3786 (5) _h_1218-GADD45A green _h_5774 (0) _h_2877-Cyclin_D1 _h_766_2-MEK1_1act_cytoplasm Par3_Par6-_h_5336 _h_2878-NT3__dimer__TRKA_1act_integral_to_membrane grey _h_1620 (0) _h_2477-Tie2_SHP2_1act _h_2750-GDP_v1 _h_2750-HRAS_GTP_1act_v2 _h_6328_2 _h_6328_4 _h_4398 grey _h_5853 (0) green _h_2569 (12) _h_4998-SHC_3O_1act_cytoplasm green _h_1507 (0) green _h_5341 (0) grey _h_4023 (0) grey _h_5063_2 (0) grey _h_5063_3 (0) grey _h_5063_1 (0) grey _h_5387 (0) grey _h_759 (0) green _h_701 (30) green _h_4683_9 (0) green _h_4683_8 (0) green _h_584 (27) green _h_4683_5 (0) green _h_4683_4 (0) green _h_4683_7 (0) green _h_4683_6 (0) green _h_4683_1 (0) green _h_4683_3 (0) green _h_4683_2 (0) green _h_2569 (4) green _h_2569 (9) alpha3_Integrin_gene-_h_5540 alpha3_Integrin_gene-_h_4558 alpha3_Integrin_gene-_h_1864 alpha3_Integrin_gene-_h_777 green _h_2569 (2) _h_4806_2-S1P1_S1P_Gi_1act_GNAI2_1act_S1P1_1act_S1P_extracellular_region green _h_5267 (3) green _h_5113 (3) green _h_766_2 (2) green _h_5291 (0) green _h_2450 (28) green _h_766_1 (2) green _h_721 (0) green _h_1476 (4) green _h_2424 (0) PLD1_1ina_plasma_membrane-_h_4608_1 PLD1_1ina_plasma_membrane-_h_1742_1 green _h_2372 (0) _h_5554-all_trans_retinal _h_5554-Arrestin _h_5554-RHO _h_5555-RET9_GFRalpha1_GDNF_SHC_Grb2_SOS1 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green _h_4191 (3) green _h_5306 (0) PKC_isoenzymes-_h_5978 PKC_isoenzymes-_h_5516_2 grey _h_4020 (0) green _h_3139 (3) green _h_4353 (0) grey _h_2369 (0) _h_1404_2-SMAD2_3_SMAD4_1act_nucleus_Smad3_2O_1act_SMAD4 CaT1_plasma_membrane-_h_52 CaT1_plasma_membrane-_h_5043 green _h_4761 (5) grey _h_1401 (0) grey _h_6273 (0) grey _h_5356 (0) grey _h_3219 (0) grey _h_2530 (0) green _h_3115 (2) green _h_5169 (0) green _h_226 (1) green _h_5463 (0) _h_1938 _h_2140 grey _h_5272_2 (0) green _h_5174 (1) grey _h_1141_2 (0) grey _h_2642_1 (0) green _h_5949 (1) grey _h_3211_1 (0) grey _h_5025_1 (0) grey _h_4426_2 (0) grey _h_1171_2 (0) green _h_3348_2 (1) grey _h_6438_2 (0) green _h_2788 (1) grey _h_4913_2 (0) green _h_3348_1 (1) grey _h_5355_2 (0) green _h_4954 (1) grey _h_2438_2 (0) _h_1174-GDP_v1 _h_1174-ARF4_GTP_1act_plasma_membrane green _h_2429 (0) green _h_5263 (0) RARs_AIB1_Cbp_p300_PCAF_9cRA_1act_AIB1_PCAF_CBP_RAR_alpha_9cRA-_h_1849_2 grey _h_434 (0) green _h_4129 (4) green _h_3235 (29) green 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_h_1082 (0) green _h_2613 (0) green _h_2659_2 (0) green _h_4256 (0) green _h_2283_2 (0) green _h_2283_1 (0) green _h_4822 (0) green _h_5079 (0) green _h_6188 (1) green _h_2659_1 (0) green _h_3959_2 (0) green _h_3959_3 (0) green _h_6366 (0) green _h_3959_1 (0) green _h_6167 (0) green _h_3235 (15) grey _h_6248 (0) green _h_6430 (0) green _h_2425 (0) green _h_298 (0) grey _h_4991 (0) green _h_5267 (2) green _h_1626 (3) green _h_4288 (3) green _h_3952 (32) green _h_3363 (3) green _h_2450 (3) green _h_4481 (1) green _h_1476 (3) grey _h_3709_1 (0) _h_71-ATF3 _h_72-Syndecan_2_Laminin_alpha3_synapse _h_958-NRIP1 _h_74-p38_alpha_1act _h_75-NADP _h_75-all_trans_retinol _h_76-IKK_alpha_1act grey _h_6346 (0) grey _h_5157 (0) _h_78-IL3_IL3RA_CSF2RB__dodecamer__YWHAZ_1act_integral_to_membrane _h_79-VEGFR2__dimer__VEGFA__dimer__1ina grey _h_1834 (0) green _h_2685 (1) red _h_1472 (1) green _h_1091 (1) grey _h_5199_2 (0) red _h_4512 (0) grey _h_3269 (0) grey _h_1456 (0) ARAP1-_h_5999 _h_2050-Ca2__v1 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_h_3071-Syndecan_4_1O_v1 _h_3070-dNp63b__tetramer__p14ARF_1ina_nucleus _h_3077-IL8_CXCR1_1act_integral_to_membrane_v1 _h_5118-TGFB_TGFBR2_TGFBR1_Par6_occludin_1act_tight_junction _h_5118-betaglycan__dimer__integral_to_membrane_v1 _h_3075-STAT1__dimer__PIAS1_1ina_nucleus _h_3074-TXA2_TP_beta_beta_Arrestin3_RAB11_GDP green _h_2794_2 (3) green _h_2794_1 (3) green _h_4755 (5) _h_5119-RIN1_1act _h_5899_59-PI3K_p110_alpha_p85_beta_1act_plasma_membrane green _h_4295 (2) _h_6127-WNT3A_FZD1_LRP6_1act_integral_to_membrane IL13_gene-_h_5671 MIR26A2_rna_gene-_h_5185 grey _h_2712 (0) green _h_335 (139) green _h_1220 (0) grey _h_3600 (0) grey _h_2772 (0) green _h_164 (0) _h_3852-Crk_Dok_R_v2 _h_3852-Crk_Dok_R_v1 grey _h_112 (0) red _h_3911 (2) grey _h_5878 (0) grey _h_5875 (0) PAK1_betaPIX_PKL_NCK1_2_cytoplasm_v1_betaPIX_PAK1_NCK2_PKL-_h_6013_2 grey _h_5665_1 (0) green _h_1329 (0) green _h_6295 (7) red _h_3740 (1) green _h_4159 (2) grey _h_388_1 (0) green _h_3622 (1) red _h_5377 (1) green _h_4696_3 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_h_2483-IL3_IL3RA_CSF2RB__dodecamer__JAK2_JAK2_SHC_1act_integral_to_membrane Vimentin-_h_2101 Vimentin-_h_5820 Vimentin-_h_4565 _h_3079-BARD1_EWS_Fli1 _h_3079-BARD1_EWS grey _h_4497 (0) grey _h_3232 (0) _h_3078-ApoB grey _h_1112 (0) green _h_2593 (0) green _h_5830 (0) green _h_2914 (0) grey _h_92 (0) grey _h_2869 (0) grey _h_2433 (0) grey _h_3372 (0) grey _h_4630 (0) grey _h_6334 (0) grey _h_5791 (0) green _h_5322 (0) green _h_5743 (0) grey _h_5862 (0) grey _h_5849 (0) green _h_4762 (0) green _h_4934 (0) _h_5899_56-PI3K_p110_alpha_p85_beta_1act_plasma_membrane grey _h_2867 (0) grey _h_3640 (0) IKK_complex_cytoplasm_v1-_h_505 IKK_complex_cytoplasm_v2-_h_1848 green _h_5463 (3) grey _h_1311 (0) Lck-_h_1358 Lck-_h_1979 Lck-_h_690 grey _h_3862_1 (0) Lck-_h_4543_1 Lck-_h_4233_4 grey _h_2166_5 (0) green _h_5043 (3) green _h_701 (13) green _h_4111 (38) green _h_3235 (9) grey _h_4942 (0) grey _h_2216_1 (0) grey _h_2216_2 (0) _h_5110-beta_catenin_cytoplasm _h_5110-APC _h_5110-WNT3A_LRP6_FZD5_DVL_Axin1_GSK3_Axin1_GSK3_1act_signalosome green _h_3228 (0) _h_5181-GDP_v1 _h_5181-CDC42_GTP_1act_cell_cell_junction _h_5180-Crk_1O_cytoplasm _h_5180-IRS1 grey _h_4354 (0) PAK1_1ina_cytoplasm-_h_6468 _h_5185-MIR26A2_rna PLD1-_h_3472_2 PLD1-_h_3508 grey _h_4714 (0) PLD1-_h_3968 PLD2-_h_6436 PLD2-_h_151 PLD2-_h_3929 PLD2-_h_6150 grey _h_4433 (0) PLD2-_h_3472_1 _h_5105_2-IL8_CXCR2_1act_early_endosome _h_5105_2-beta_Arrestin2 _h_5105_2-AP_2_adaptor_complex _h_5188-IL2_IL2R_alpha_beta_gamma_JAK1_LCK_JAK3_SYK_1act_integral_to_membrane grey _h_6477 (0) _h_5105_1-IL8_CXCR2_1act_early_endosome _h_5105_1-beta_Arrestin1 _h_5105_1-AP_2_adaptor_complex green _h_2209 (0) grey _h_2961 (0) PIP5K1C-_h_1718 PIP5K1C-_h_3959_2 _h_168_4-FOXO3a_14_3_3_family_1ina_cytoplasm_YWHAQ_FOXO3A_1O_1ina_2O _h_168_2-FOXO3a_14_3_3_family_1ina_cytoplasm_FOXO3A_1O_1ina_2O_YWHAS _h_168_3-FOXO3a_14_3_3_family_1ina_cytoplasm_14_3_3_E_FOXO3A_1O_1ina_2O _h_168_1-FOXO3a_14_3_3_family_1ina_cytoplasm_YWHAG_FOXO3A_1O_1ina_2O _h_1747-eIF4E_1O_1act _h_1746-INI1_BRG1_BAF57_ER_beta_GIOT_4 _h_1745-IL2R_alpha_integral_to_membrane _h_1744-SHP2_1act_1O _h_1743-CEBPD NME1_gene-_h_1995 green _h_2754 (0) green _h_4221 (0) CKM_gene-_h_1453 grey _h_5294 (0) grey _h_102 (0) _h_5558-RORA4 DOCK7-_h_4224 _h_3679-CREB1_1O_1act_nucleus _h_3671-NFATc_A_alpha_cytoplasm _h_3670-TAp63g__tetramer__1act_nucleus_v3 _h_3673-NOTCH1_heterodimer_sDelta_1_1act_integral_to_membrane _h_1019-PSA grey _h_4416 (0) grey _h_2322 (0) _h_3674-PAK4_1act _h_969_2-SMAD2_3_SMAD4_SP1_MIZ_1_1act_nucleus_SMAD2_2O_1act_SP1_SMAD4_MIZ_1 _h_2821_1-SMAD2_3_SMAD4_FOXO1_3a_4_CEBPB_1act_nucleus_CEBPB_SMAD2_2O_1act_FOXO1_3a_4_1act_SMAD4 grey _h_3343 (0) KRAS_isoform_4B_GTP_1act_plasma_membrane-_h_5546 KRAS_isoform_4B_GTP_1act_plasma_membrane-_h_4191 grey _h_4457 (0) _h_5459-TLE1_nucleus _h_5459-LEF1_beta_catenin_1act_nucleus_v1 _h_5458-PI3K_BCAP_CD19_1act_plasma_membrane 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(0) GSK3beta_cytoplasm-_h_344 GSK3beta_cytoplasm-_h_5974 GSK3beta_cytoplasm-_h_6129 grey _h_977 (0) grey _h_1301 (0) grey _h_3661 (0) grey _h_5081 (0) grey _h_4130 (0) grey _h_6282 (0) grey _h_276 (0) grey _h_6222 (0) grey _h_2746 (0) grey _h_2245 (0) grey _h_1295 (0) grey _h_4769 (0) _h_3023_1-Ephrin_A1_EPHA4_VAV2_VAV3_1act_integral_to_membrane_VAV2_EPHA4_2O_Ephrin_A1 _h_3023_2-Ephrin_A1_EPHA4_VAV2_VAV3_1act_integral_to_membrane_Vav3_EPHA4_2O_Ephrin_A1 _h_5186-PSA HSORC1_gene-_h_3509 _h_2300_1-p38alpha_beta_MKP5_1ina_MKP5_1act_p38_beta_1ina CTLA4_gene-_h_5409 POLA_gene-_h_2743 green _h_3679 (6) _h_630-JUN_FOS_1act_nucleus_v1 ADORA2B_gene-_h_3720 IL1RA_gene-_h_2398 TF_gene-_h_4996 _h_5477-Syndecan_2_Ezrin_cytoskeleton _h_2157-LAT_GRAP2_SLP76_VAV1_NCK1_1act_integral_to_membrane _h_2156-FANCD2_1O_1O _h_2155-TAT Src_1ina_cytoplasm-_h_1281 _h_2153-alphav_beta5_Integrin_CYR61_integral_to_membrane _h_2152-BAD_PKC_delta_Alpha_Synuclein green _h_3054 (3) _h_2150-XIAP_DIABLO_1ina grey _h_2611 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_h_5031 (3) green _h_4325 (0) grey _h_338 (0) green _h_1703 (6) grey _h_1199 (0) grey _h_417 (0) green _h_1554 (0) grey _h_1803 (0) HGF_dimer__MET_dimer__1act_integral_to_membrane_v1-_h_3444 green _h_748 (0) grey _h_3246 (0) HGF_dimer__MET_dimer__1act_integral_to_membrane_v1-_h_4192 green _h_4242 (0) grey _h_5649 (0) grey _h_378 (0) grey _h_2843 (0) HGF_dimer__MET_dimer__1act_integral_to_membrane_v1-_h_4764 grey _h_2837 (0) HGF_dimer__MET_dimer__1act_integral_to_membrane_v1-_h_226 grey _h_6374 (0) MKK3_cytoplasm-_h_1343 green _h_2426 (0) green _h_335 (99) MGAT3-_h_1982 green _h_76 (0) green _h_4241 (1) green _h_3445 (0) green _h_5853 (0) _h_1121 grey _h_3654_8 (0) grey _h_3654_4 (0) H2AZ_gene-_h_5529 Histone_H4_1N-_h_115 Aurora_B_gene-_h_6165 _h_275-ZO_1_cell_cell_junction TRPV1_cytoplasm-_h_1754 grey _h_6414 (0) PTEN_v2_gene-_h_1472 PTEN_v2_gene-_h_6424 _h_5370-Calcineurin_1act _h_1626-Eps8_ABI1_SOS1_v2 _h_2665-cPLA2_alpha_1act_1O TID1-_h_6413 grey _h_4270 (0) grey _h_4043 (0) grey _h_399_1 (0) grey _h_399_2 (0) grey _h_399_3 (0) grey _h_2713_1 (0) grey _h_2713_3 (0) grey _h_2713_2 (0) grey _h_3362 (0) grey _h_557 (0) grey _h_5323 (0) grey _h_4651 (0) grey _h_3719 (0) grey _h_2230_1 (0) grey _h_2230_2 (0) grey _h_2620 (0) grey _h_144 (0) BRCA2_gene-_h_3734 BRCA2_gene-_h_973 BRCA2_gene-_h_4623 BRCA2_gene-_h_6237 red _h_3873 (0) green _h_6462 (0) grey _h_2317 (0) _h_4668_3 _h_4668_2 _h_4668_3 _h_4668_1 PDX1_gene-_h_2738 green _h_4064 (1) _h_991-dNp63a__tetramer__PP2A_B56alpha_GSK3beta_nucleus _h_992-alpha2_beta1_Integrin_Laminin_2_integral_to_membrane _h_993-HDAC4_RFXANK_nucleus _h_994-S1P1_1act grey _h_3131_1 (0) grey _h_3131_2 (0) grey _h_3131_3 (0) _h_996-SMC1_2O_site_of_double_strand_break _h_449-Cyclin_A _h_999-PMS2 green _h_3770_7 (5) green _h_3770_6 (5) green _h_3770_5 (5) green _h_3770_4 (5) green _h_3770_3 (5) green _h_3770_2 (5) green _h_3770_1 (5) grey _h_1183 (0) green _h_3770_8 (5) green _h_3770_9 (5) grey _h_5888 (0) _h_443-Nemo_like_kinase_1p_1act 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NF_kappa_B1_p50_RelA_I_kappa_B_alpha_cytoplasm_v1-_h_3590 NF_kappa_B1_p50_RelA_I_kappa_B_alpha_cytoplasm_v2-_h_1996 grey _h_5386 (0) NF_kappa_B1_p50_RelA_I_kappa_B_alpha_cytoplasm_v2-_h_5463 NF_kappa_B1_p50_RelA_I_kappa_B_alpha_cytoplasm_v2-_h_1530 grey _h_408 (0) NF_kappa_B1_p50_RelA_I_kappa_B_alpha_cytoplasm_v2-_h_2534 _h_3366 _h_3366 Ran_GTP_Exportin_1_HDAC4_nucleus-_h_6470 MLCK-_h_1653 MLCK-_h_5629 _h_192-FGFR1_1act_growth_cone _h_193-BRCA1_BARD1 _h_666-TFF1_v2 _h_667-Cyclin_E _h_196-STAT3__dimer__active_1act_nucleus _h_197-NGF__dimer__extracellular_region _h_1310-TMPRSS2 grey _h_2474 (0) grey _h_1307 (0) grey _h_2720 (0) grey _h_1635 (0) grey _h_1228 (0) grey _h_3876 (0) grey _h_6137 (0) grey _h_5025_1 (0) grey _h_4504 (3) grey _h_3914 (1) grey _h_5025_2 (0) grey _h_5062 (0) grey _h_4613 (0) grey _h_2514 (0) grey _h_1415 (0) _h_1633-PPAR_Delta _h_2938-p53 grey _h_5556 (0) grey _h_669 (0) grey _h_2603 (0) grey _h_5254 (1) grey _h_989 (0) grey _h_3799 (0) grey _h_2315 (0) grey 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_h_2583-netrin_1_DCC_translation_initiation_complex_1act_integral_to_membrane _h_2588-LIS1_IQGAP1 _h_2588-CaM_Ca2_ _h_2589-TRAIL_TRAILR2_FADD_integral_to_membrane red _h_1353 (0) COL1A1_gene-_h_5843 grey _h_4866 (0) _h_5129-IKK_complex_cytoplasm_v2 CPI17-_h_5542 IL4_extracellular_region_gene-_h_2123 IL4_extracellular_region_gene-_h_2725 IL4_extracellular_region_gene-_h_5980 IL4_extracellular_region_gene-_h_1947 IL4_extracellular_region_gene-_h_5530 IL4_extracellular_region_gene-_h_2202 IL4_extracellular_region_gene-_h_2182 IL4_extracellular_region_gene-_h_4468 IL4_extracellular_region_gene-_h_3313 IL4_extracellular_region_gene-_h_5656 _h_5125-AFP _h_5124-JUN_FOS_1act_nucleus_v1 _h_5120-MDM2_UBCH5_v2 _h_6036 AKT2_cytoplasm-_h_2887 _h_5484 _h_5484 _h_1729-Src_1O_plasma_membrane _h_1728-TCF4E_beta_catenin_p300_1act_nucleus _h_6119-PP2A_Heterotrimer_1act grey _h_3415 (0) _h_6115-LRP6_DKK1_1ina_endosome _h_6114-DDB2 _h_1721-Granzyme_A _h_1720-SIN3_HDAC_complex_Mad_Max_nucleus 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_h_2248_2-JUNB_Fra1_NFAT1_c_4_1act_nucleus_NFAT1_1O_7O_2s_1act_nucleus_Fra1_JUNB _h_2248_3-JUNB_Fra1_NFAT1_c_4_1act_nucleus_NFATc_1act_nucleus_Fra1_JUNB green _h_3054 (13) green _h_4083 (0) grey _h_3537 (0) grey _h_91 (0) grey _h_3035 (0) grey _h_1283 (0) green _h_1268 (0) green _h_5971 (0) green _h_4986 (0) green _h_797 (0) green _h_3018 (0) _h_5051_30-PI3K_delta_1act_plasma_membrane _h_5356-sTNF_alpha_TNFR1A_FAN_NSMASE_1act_integral_to_membrane _h_5357-TFF1_v2 _h_5350-brachyury _h_5351-IL1_beta_fragment_1act green _h_89 (1) green _h_5692 (0) green _h_114 (0) green _h_4600 (0) green _h_2310 (0) _h_5353-VEGF_Rho_ROCK_alphav_beta3_Integrin_1act_plasma_membrane red _h_763 (2) green _h_6456 (0) green _h_3267 (0) red _h_5511 (2) green _h_4945 (0) EGR1-_h_1642 green _h_1917 (0) _h_5358-GR_alpha_HSP90_FKBP51_HSP90_PP5C grey _h_1813_3 (0) grey _h_1813_2 (0) grey _h_1813_1 (0) _h_1444-YAP65 _h_1445-RALGDS_1act_plasma_membrane _h_1446-PKC_theta_SPAK_1act _h_1447-SPHK1_1act 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_h_2225-IKK_alpha_1O_cytoplasm _h_1415-p62DOK_RasGAP_v1 _h_1415-p62DOK_RasGAP_v2 _h_2224-MYC _h_1414-Akt1_plasma_membrane GLI2_Su_fu__1ina_cytoplasm-_h_24 green _h_1291 (1) green _h_6488 (1) green _h_2085 (2) green _h_4782 (1) _h_5173_1-Jnk1_1O_1act_1O_nucleus _h_4231_2-p38alpha_beta_MAPKAPK2_1act_MAPKAPK2_4O_1O_p38_alpha_1O_1O_1act_v2 PKM_gene-_h_6343 red _h_5231 (0) SHP2_1act_1O_cytoplasm-_h_2206 PP2A_cytoplasm-_h_5414 _h_2328_2-JUN_JUN_FOS_BAG1_1act_nucleus_JUN_BAG1_JUN_2O_2O _h_2328_1-JUN_JUN_FOS_BAG1_1act_nucleus_BAG1_FOS_JUN_2O_2O JUN_FOS_nucleus_v2-_h_4542 _h_1612_1 _h_938_4-RAF1_14_3_3_1ina_cytoplasm_RAF1_1O_14_3_3_E _h_5741-GDP_v1 _h_5741-ARF1_GTP_1act_plasma_membrane _h_938_6-RAF1_14_3_3_1ina_cytoplasm_RAF1_1O_YWHAG _h_938_1-RAF1_14_3_3_1ina_cytoplasm_RAF1_1O_YWHAS _h_5746-TAT _h_938_3-RAF1_14_3_3_1ina_cytoplasm_RAF1_1O_YWHAQ _h_938_2-RAF1_14_3_3_1ina_cytoplasm_RAF1_1O_YWHAZ grey _h_1970 (0) _h_5749-ErbB4_ErbB4_neuregulin_1_beta_neuregulin_1_beta_Fyn_1act_integral_to_membrane 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_h_2264_2 (0) red _h_3241 (0) green _h_2456 (0) grey _h_1240 (0) mTORC1_PRAS40_DEPTOR_1ina_perinuclear_region_of_cytoplasm-_h_3621 APS_plasma_membrane-_h_3496 green _h_4312 (0) green _h_5432 (0) grey _h_26 (0) green _h_4157 (0) green _h_1054 (0) green _h_5224 (0) green _h_3952 (35) green _h_4256 (1) green _h_1169 (0) grey _h_3791 (0) green _h_4789 (0) grey _h_5990 (0) red _h_724 (0) green _h_5254 (0) _h_6193-HES1_JAK2_1act_nucleus Spermine_extracellular_region-_h_5973 _h_5830-brachyury _h_2944_26-FGFR1c_FGF6_nucleus grey _h_1231 (0) grey _h_3594 (0) grey _h_3353 (0) grey _h_159 (0) _h_2944_23-FGFR1b_FGF10_nucleus _h_2944_20-FGFR1b_FGF1_nucleus _h_2944_21-FGFR1b_FGF1_nucleus _h_2944_28-FGFR1c_FGF1_nucleus green _h_183 (0) grey _h_1450_2 (0) _h_689-GR_beta_TIF2_nucleus _h_689-cortisol_GR_alpha__dimer__TIF2_nucleus grey _h_4577 (0) grey _h_5024 (0) ENG_L_gene-_h_4083 green _h_701 (27) red _h_4129 (25) grey _h_494 (0) _h_680-PSA _h_682-Laminin_gamma1 _h_683-Akt1_1O_1act_plasma_membrane_v2 _h_4526-RHEB_GTP_BNIP3_1ina _h_686-JUN_FOS_1act_nucleus_v2 _h_687-proNGF__dimer__p75_NTR__Sortilin_Necdin_1act_integral_to_membrane _h_687-E2F1_nucleus JPO1_gene-_h_5967 PAP_2a_gene-_h_4892 _h_4784-YWHAZ__dimer__RAF1_1act green _h_2227 (6) red _h_2838 (0) FOXO1-_h_655 _h_6227-VEGFR2__dimer__VEGFA145__dimer__1act_integral_to_membrane _h_4522-IL8_cytoplasm green _h_38 (3) FOXO4-_h_1385 _h_1556-CD4 _h_4835-Histone_H1b_1a_1act_1N HES1_nucleus_gene-_h_1880 HES1_nucleus_gene-_h_793 HES1_nucleus_gene-_h_5167 HES1_nucleus_gene-_h_1521 HES1_nucleus_gene-_h_3913 grey _h_3214_2 (0) grey _h_2778 (0) grey _h_3392_2 (0) grey _h_4297_1 (0) green _h_2761_2 (0) green _h_2761_3 (0) green _h_2761_1 (0) grey _h_6478 (0) PI3K_plasma_membrane-_h_807_37 PI3K_plasma_membrane-_h_807_53 PI3K_plasma_membrane-_h_807_26 PI3K_plasma_membrane-_h_807_21 grey _h_5458 (1) PI3K_plasma_membrane-_h_807_30 grey _h_1131 (0) PI3K_plasma_membrane-_h_807_62 PI3K_plasma_membrane-_h_807_39 PI3K_plasma_membrane-_h_135 PI3K_plasma_membrane-_h_807_9 PI3K_plasma_membrane-_h_3645 grey _h_2014 (0) grey _h_698 (0) PI3K_plasma_membrane-_h_807_11 PI3K_p110_delta_p85_beta_cytoplasm-_h_5899_21 PI3K_p110_delta_p85_beta_cytoplasm-_h_5899_7 PI3K_p110_delta_p85_beta_cytoplasm-_h_5899_67 PI3K_p110_delta_p85_beta_cytoplasm-_h_5899_28 PI3K_p110_delta_p85_beta_cytoplasm-_h_5899_70 PI3K_p110_delta_p85_beta_cytoplasm-_h_5899_69 PI3K_p110_delta_p85_beta_cytoplasm-_h_5899_43 PI3K_p110_delta_p85_beta_cytoplasm-_h_5899_79 PI3K_p110_delta_p85_beta_cytoplasm-_h_5899_41 green _h_2585 (6) green _h_3212 (8) green _h_4074 (4) green _h_6097 (6) green _h_1572 (10) green _h_1378 (6) green _h_457 (1) grey _h_3400_1 (0) Ephrin_B1_EPHB1_2_Src_Family_Kinases_1act_membrane_raft_Ephrin_B1_1O_EPHB1_2_Lck_1O_1act-_h_1021_4 _h_3939-BCL6 _h_5815-T_DHT_AR_CyclinD1_nucleus green _h_6121 (1) _h_1979-Src_Family_Kinase_active_1act _h_161_2-MYC_Max_Cbp_p300_1act_nucleus_MYC_1O_1u_v2_CBP_Max 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grey _h_97 (0) green _h_430 (1) green _h_389 (0) green _h_2622 (0) green _h_3993 (13) red _h_5821 (0) green _h_2962 (0) grey _h_6495 (0) green _h_3903 (0) green _h_1221 (0) green _h_1206 (0) green _h_5018 (0) green _h_1564 (0) green _h_3395 (0) HIF1A_ARNT_nucleus-_h_67 green _h_2192 (0) green _h_5239 (0) green _h_5745 (0) green _h_4579 (0) green _h_6434 (0) grey _h_1069_1 (0) grey _h_1069_2 (0) green _h_3028 (0) green _h_3382 (0) green _h_165 (0) green _h_3345 (0) green _h_1569 (0) green _h_379 (0) green _h_1503 (0) green _h_5780 (0) green _h_426 (0) green _h_3979 (0) green _h_6068 (0) green _h_3940 (0) green _h_3832 (0) green _h_1216 (0) green _h_2287 (0) green _h_1198 (0) green _h_3625 (0) green _h_3332 (0) green _h_64 (0) green _h_4795 (0) green _h_1869 (0) green _h_5776 (0) green _h_2974 (0) green _h_5558 (0) green _h_3547 (0) green _h_6398 (0) green _h_5429 (0) green _h_2129 (2) green _h_4292 (0) green _h_3506 (0) green _h_1605 (0) green _h_4996 (0) green _h_6343 (0) green _h_1656 (0) ANF_gene-_h_4 _h_1271_1-Erk2_1O_1O_1act_cytoplasm Yes_1ina-_h_1043_4 green _h_1703 (1) grey _h_497_1 (0) green _h_5308 (1) green _h_1663 (0) green _h_3904 (9) green _h_335 (132) green _h_3993 (8) grey _h_5284 (0) HSP60_gene-_h_4056 HSP60_gene-_h_6485 green _h_4059_2 (4) green _h_4262 (0) green _h_4059_1 (4) proBDNF__dimer__p75_NTR__Sortilin_TRAF6_NRIF_1act_integral_to_membrane-_h_3396 grey _h_1779 (0) green _h_270 (1) green _h_5583 (1) _h_4236-NEMO_1u_cytoplasm grey _h_2834 (0) _h_200-PERP green _h_4003 (1) green _h_1117 (3) green _h_397 (7) mTOR-_h_1951 grey _h_2200 (0) mTOR-_h_5087 _h_3650_1-NFAT1_c_4_ICER1_1act_nucleus_ICER1_NFAT1_1O_7O_2s_1act_nucleus _h_3650_1-JUN_FOSNFAT1_c_4_1act_nucleus_c_Jun_2O_NFAT1_1O_7O_2s_1act_nucleus_FOS_1O_1O MYCT1_gene-_h_4845 green _h_3972 (0) GSK3beta_1act-_h_5345 green _h_351 (0) green _h_2025 (0) _h_27_3-RB1_E2F1_3_Elf1_nucleus _h_27_2-RB1_E2F1_3_Elf1_nucleus _h_27_1-RB1_E2F1_3_Elf1_nucleus grey _h_3797 (2) RAP1_GDP_1ina-_h_5454 grey _h_4381 (0) 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grey _h_178_3 (0) grey _h_6439 (0) grey _h_178_1 (0) _h_5657 grey _h_178_2 (0) grey _h_4105_1 (0) grey _h_4105_2 (0) grey _h_4105_3 (0) grey _h_5748 (0) grey _h_3650_1 (0) grey _h_3650_2 (0) grey _h_3650_3 (0) _h_6086-TNF_alpha_extracellular_region _h_3109-LPL _h_3108-E_cadherin_Ca2__beta_catenin_alpha_catenin_p120_catenin_EPLIN_cell_cell_junction _h_3107-alpha8_beta1_Integrin_nephronectin_integral_to_membrane _h_3106-clathrin_heavy_chain_synaptic_vesicle_membrane _h_3105-RXRs_LXRs_DNA_Oxysterols_1act_v2 _h_3105-RXRs_LXRs_DNA_9cRA_1act _h_3105-RXRs_LXRs_DNA_Oxysterols_1act_v1 _h_429_1-14_3_3_family_chibby_beta_catenin_1ina_cytoplasm_chibby_beta_catenin_YWHAZ WAVE1_Sra1_Nap1_HSPC300_ABI2_1ina_cytoplasm-_h_5925 _h_3102-Aurora_A_TPX2_spindle_pole _h_429_4-14_3_3_family_chibby_beta_catenin_1ina_cytoplasm_chibby_beta_catenin_YWHAG _h_3100-p70S6K_2O_4O grey _h_3732 (0) _h_5051_13-PI3K_p110_delta_p85_beta_1act_plasma_membrane Myb_gene-_h_4459 Myb_gene-_h_2487 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green _h_4978 (0) _h_4210-alpha6_beta4_Integrin_Laminin_2_integral_to_membrane _h_807_57-PI3K_p110_alpha_p55_gamma_1act_plasma_membrane _h_807_58-PI3K_p110_delta_p55_gamma_1act_plasma_membrane _h_572-VEGFR2__dimer__VEGFA189__dimer__1act_integral_to_membrane NDRG1_gene-_h_49 NDRG1_gene-_h_2937 NDRG1_gene-_h_3332 _h_4219-GLX2 green _h_4295 (11) green _h_1510 (0) green _h_6307 (0) green _h_188 (0) _h_1471-FAK_1O _h_1047-alpha3_beta1_Integrin_Entactin_integral_to_membrane _h_1984_2-FGFR_FGF_Syndecan_2_1act Leptin_gene-_h_64 green _h_3679 (9) grey _h_3387 (0) CASR_1ina_integral_to_membrane-_h_364 _h_1470-SCF_KIT_EPO_EPOR_1act grey _h_3073 (0) _h_5051_53-PI3K_p110_beta_p85_beta_1act_plasma_membrane green _h_4930 (0) grey _h_2844 (0) green _h_2350 (0) green _h_3012 (0) green _h_868 (0) _h_5622_1-PI3K_gamma_p101_1act _h_5622_2-PI3K_gamma_p84_1act green _h_4852 (1) grey _h_5672 (0) grey _h_2344 (0) green _h_1372 (0) green _h_1271_1 (1) green _h_1271_2 (1) green _h_5539 (1) 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grey _h_2166_2 (0) Yes-_h_4233_1 green _h_761_1 (0) green _h_761_2 (0) _h_1369-SH2B_family_GRB2_SOS1_1act _h_2633-GDP_v1 _h_2633-GNAI2_GTP_1act_v2 _h_2633-GNB1_GNG2_1act _h_241-DAB1_LIS1 grey _h_1670 (0) grey _h_837 (0) grey _h_6006 (0) green _h_1717 (0) grey _h_4674 (0) green _h_4620 (0) green _h_4985 (1) grey _h_6381_4 (0) grey _h_3357 (0) green _h_1110 (0) green _h_4259 (0) grey _h_6381_1 (0) grey _h_6381_2 (0) grey _h_6381_3 (0) grey _h_2797 (0) Glucocorticoid_Receptor_gene-_h_6018 _h_1036_121-alpha2_beta1_Integrin_endosome Dicer_gene-_h_2347 Dicer_gene-_h_2226 Dicer_gene-_h_311 _h_1036_123-alpha11_beta1_Integrin_endosome _h_1036_122-alpha9_beta1_Integrin_endosome _h_1036_125-alpha3_beta1_Integrin_endosome grey _h_5736 (0) _h_1036_127-alpha9_beta1_Integrin_endosome _h_1036_126-alpha3_beta1_Integrin_endosome _h_3297-EGR3 _h_3296-COL18A1 grey _h_201_2 (0) grey _h_201_3 (0) grey _h_201_1 (0) grey _h_201_6 (0) grey _h_201_4 (0) grey _h_201_5 (0) _h_3294-SAA1_TLR2_TLR1_1act_integral_to_membrane _h_3293-RELN_VLDLR_DAB1_LIS1_PAFAH1B2_PAFAH1B3 _h_3292-ELMO1_DOCK2_1act_cell_leading_edge grey _h_5100 (0) grey _h_560 (0) grey _h_3896 (0) _h_5629-MLCK_1O _h_5624-VEGFR2_3__dimer__VEGFC__dimer__NRP2_1act_integral_to_membrane _h_5625-MYC _h_5626-Bam32_1O_1act _h_5627-GNAT2_GDP_1ina _h_5627-Cone_PDE6_1act _h_5627-phosphate _h_5621-VEGFR1_homodimer_NRP1_VEGFR_121_plasma_membrane _h_547-CABIN1_MEF2D_CaM_Ca2__CAMK_IV_1ina_nucleus _h_2774 _h_545-Ephrin_B_EPHB1_Src_p52_SHC_GRB2_1act_integral_to_membrane green _h_2117 (7) red _h_3403 (1) red _h_4912 (0) _h_541-STAT3__dimer__active_1act_v1 green _h_2486 (0) 12R_LOX_gene-_h_2906 grey _h_812 (0) grey _h_3157 (0) EGF_EGFR-_h_1004 _h_6148-Nephrin_NEPH1_podocin_PLCgamma1_membrane_raft _h_548-p53__tetramer__nucleus_v9 grey _h_2455 (0) BoNT_D__Light_Heavy__extracellular_region-_h_510 PIG3_gene-_h_4010 PIG3_gene-_h_205 PIG3_gene-_h_4469 PIG3_gene-_h_2528 PIG3_gene-_h_203 _h_5997-MT2A _h_5994-ARAP3_RAP1A_GTP_1act _h_5992-STAT4__dimer__1ina_integral_to_membrane _h_5993-p21CIP1_1ina _h_5990-GDP_v1 _h_5990-ETA_receptor_Endothelin_1_G12_GTP_1act_integral_to_membrane SNAP25_1act_plasma_membrane-_h_1846 SNAP25_1act_plasma_membrane-_h_4790 grey _h_3003_2 (0) grey _h_3003_3 (0) green _h_156 (4) green _h_3827 (1) green _h_644 (1) green _h_4137 (1) green _h_3679 (2) green _h_3333 (1) green _h_3002 (1) green _h_198 (1) green _h_5492 (1) green _h_2786 (1) _h_5998-GDP_v1 _h_5998-ARF5_GTP_1act grey _h_3571 (0) _h_67-HIF1A_ARNT_1act_nucleus green _h_555_2 (2) green _h_555_1 (2) _h_4376-SMAD2_2O_1act_cytoplasm green _h_4676 (0) _h_722-MYC_Max_PML4_1ina_nucleus _h_721-ASM_1ina _h_720-EGR1 _h_727-Axin2 grey _h_4222 (0) _h_2944_9-FGFR1b_FGF3_nucleus _h_2944_8-FGFR1c_FGF4_nucleus _h_2944_7-FGFR1c_FGF4_nucleus _h_2944_6-FGFR1b_FGF10_nucleus _h_6133 _h_6133 _h_728-IL8_CXCR1_1act_integral_to_membrane_v2 _h_2944_3-FGFR1c_FGF2_nucleus _h_2944_2-FGFR1b_FGF3_nucleus _h_2944_1-FGFR1b_FGF2_nucleus _h_1611_2-RAS_family_GTP_1act_H_RAS_isoform_1_GTP_v1 _h_1611_2-GDP_v1 _h_896-Ca2__v1 _h_896-sN_cad_extracellular_region _h_896-N_cad_CTF1_beta_catenin_gamma_catenin_alpha_catenin_p120_catenin_integral_to_membrane p70S6K_1O_4O-_h_3100 _h_6147 _h_60-FADD_FADD_CASP8_CASP8_endosome _h_60-FASLG_FAS__trimer_ grey _h_4318 (0) _h_718-NOS2 Na___extracellular_region-_h_5775 grey _h_3195 (0) grey _h_1246_1 (0) green _h_2665 (0) green _h_4058_1 (3) green _h_335 (100) _h_1284 _h_383-SHH _h_2144-EGFR_EGFR_EGF_EGF_1act_endosome_v2 grey _h_3853_1 (0) TAp63a__tetramer__nucleus-_h_482 TAp63a__tetramer__nucleus-_h_3751 TAp63a__tetramer__nucleus-_h_4362 grey _h_2950 (0) Caspase_3_p18-_h_5078 Caspase_3_p18-_h_5027 _h_2410-PYK2_SHP2_cytoplasm _h_2410-FGFR3_FGF_complex_Pyk2 _h_4869-PKC_delta_1O_1act _h_4868-GIT1_betaPIX_PAK1_centrosome _h_2147-p53__tetramer__nucleus_v6 _h_5899_48-PI3K_p110_delta_p55_gamma_1act_plasma_membrane 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_h_3778-G_beta_gamma_PI3K_gamma_p84_1act_integral_to_membrane _h_5417-E2F5_DP_v1 _h_3263_81-Ca2__v1 _h_3263_81-alpha_catenin_cytoplasm _h_3263_81-p120_catenin_cytoplasm _h_3263_81-FGFR1c_FGF4_early_endosome _h_3263_81-E_cadherin_beta_catenin_early_endosome_v2 _h_3263_80-Ca2__v1 _h_3263_80-FGFR1c_FGF6_early_endosome _h_3263_80-alpha_catenin_cytoplasm _h_3263_80-E_cadherin_beta_catenin_early_endosome_v2 _h_3263_80-p120_catenin_cytoplasm _h_855-SMAD2_1act_2O_1p_cytoplasm _h_1215_2-RAS_family_GTP_1act_plasma_membrane_H_RAS_isoform_1_GTP_v1 _h_1215_2-GDP_v1 _h_1215_1-RAS_family_GTP_1act_plasma_membrane_N_RAS_GTP_v1 _h_1215_1-GDP_v1 grey _h_1557 (0) _h_2421-CPCI _h_1202-FA_complex_FANCD2_Ubiquitin_nuclear_speck IL13_extracellular_region_gene-_h_1087 _h_1203-p14ARF grey _h_4833 (0) grey _h_6305 (0) grey _h_4886_3 (0) _h_254_4-alpha6_beta4_Integrin_Laminin_14_3_3_hemidesmosome_alpha6_Integrin_Laminin_Gamma_YWHAB_Laminin_Alpha_beta4_integrin_1O_Laminin_beta1 _h_1201-MIR9_3_rna grey _h_228_1 (0) PLC_beta_2_cytoplasm-_h_3553 grey _h_2485_2 (0) PLC_beta_2_cytoplasm-_h_1373_1 _h_5587-GLUT1 _h_4399-CDC25C_1O_cytoplasm _h_254_6-alpha6_beta4_Integrin_Laminin_14_3_3_hemidesmosome_alpha6_Integrin_Laminin_Gamma_Laminin_Alpha_beta4_integrin_1O_YWHAS_Laminin_beta1 green _h_1967 (0) _h_1108_2-beta_catenin_cytoplasm _h_1108_2-WNT3A_LRP6_FZD5_Axin1_GSK3_1act_integral_to_membrane_FZD5_WNT3A_2N_1S_1O_LRP6_1O_1O_GSK3beta_Axin1 _h_1108_2-APC _h_4392-PSA _h_4391-EGR1_nucleus K5_gene-_h_3915 K5_gene-_h_3185 K5_gene-_h_2661 K5_gene-_h_1496 _h_4397-IQGAP1_1p_cytoplasm _h_4396-EBAG9 _h_4395-p53__tetramer__1ina_nucleus _h_4394-SOCS3 PICH_chromosome-_h_4629 green _h_5751 (0) grey _h_51 (0) grey _h_4315 (0) grey _h_6227 (0) _h_4844-PRL_1_alpha_Tubulin green _h_6445 (0) grey _h_3024 (0) _h_1650_2-p38alpha_beta_CK2_1act__alpha_2__beta_2CK2_1act_p38_alpha_1O_1O_1act_v2 ZCCHC12_gene-_h_2593 _h_5051_25-PI3K_p110_beta_p85_beta_1act_plasma_membrane PGRB_gene-_h_5208 PGRB_gene-_h_1814 grey _h_2199 (0) green 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green _h_3235 (4) FOXO1_14_3_3_family_nucleus_v2_YWHAZ_FOXO1_1O_2O-_h_2760_2 _h_4112-STAT1_1O_cytoplasm _h_5333-STAT1__dimer__1ina_nucleus green _h_3797 (0) grey _h_2793 (0) grey _h_606 (1) grey _h_5933 (0) _h_5143-MHC_1A FOXO3A_14_3_3_nucleus_YWHAB_FOXO3A_1O_1O-_h_66_4 grey _h_6040 (0) grey _h_1541 (0) grey _h_4160 (0) _h_94-IL1RAP grey _h_2366 (0) Cyclin_D2_gene-_h_771 Cyclin_D2_gene-_h_6241 Cyclin_D2_gene-_h_4287 _h_2837-HGF_dimer__MET_dimer__GRB2_1act_integral_to_membrane _h_3189_2-STAT1__dimer__1act_v1 green _h_5498 (0) grey _h_4384 (0) green _h_6331 (0) green _h_6433 (0) IL1RAP_gene-_h_94 FGFR1_integral_to_membrane-_h_192 grey _h_2357 (0) grey _h_2051 (0) neutrophil_elastase_gene-_h_5688 _h_1171_1-FAK_Src_Yes_Fyn_JIP3_1act_focal_adhesion_JIP3_1act_1O_Fyn_1O_1act_FAK_6O_1act _h_886-LNK_1act_plasma_membrane _h_887-CXCL11_CXCR3_alt_integral_to_membrane _h_887-GDP_v1 _h_887-GNB1_GNG2_1act_cytoplasm _h_887-GNAI2_GTP_1act_v1 _h_884-COL1A2 _h_885-SMAD3_SMAD4_SP1_1act_nucleus green _h_3555 (0) red _h_1350 (0) green _h_1428 (0) green _h_2220 (0) green _h_397 (3) green _h_393 (0) green _h_3736 (2) green _h_6034 (0) green _h_2010 (0) green _h_2323 (2) _h_888-Btk_1act _h_889-Chromosomal_passenger_complex_EVI5_1act_midbody _h_2434_40-PI3K_beta_1act_plasma_membrane grey _h_986 (0) _h_2434_42-PI3K_beta_1act_plasma_membrane _h_2434_43-PI3K_p110_delta_p55_gamma_1act_plasma_membrane _h_2434_44-PI3K_p110_delta_p85_beta_1act_plasma_membrane _h_2434_47-PI3K_p110_alpha_p85_beta_1act_plasma_membrane RhoC-_h_4414 green _h_6344 (1) green _h_4491 (0) grey _h_2407 (0) grey _h_3470 (0) grey _h_6437 (0) grey _h_4871 (0) grey _h_5422 (0) _h_3554-p53_1O _h_3554-p53_1ina_1O _h_3555-OX40 _h_3556-SLC25A3 _h_1520 _h_3550-BRAF_1O_1act_plasma_membrane _h_3551-PDGF_PDGFRA_Caveolin_3_1act _h_3552-RET51_GFRalpha1_GDNF_FRS2_SHP2_Grb2_membrane_raft _h_3553-PLC_beta_2_1act_cytoplasm _h_561-beta_catenin_duplin_1ina_nucleus _h_3558-E2FBP1 grey _h_3906 (0) green _h_701 (28) WAVE2_Nap1_Sra1_AbI1_HSPC300_1ina_cytoplasm-_h_5045 grey _h_2787 (1) green _h_2002 (2) _h_5829_2-LPA_LPA1_2_3_LPA3_plasma_membrane_LPA green _h_4203 (1) grey _h_338 (0) GRB2_GAB1-_h_1386 grey _h_4409 (0) grey _h_1923 (0) green _h_3634 (0) green _h_5519 (0) grey _h_4829 (0) green _h_4417 (0) green _h_1275 (0) _h_2637_6-PI3K_delta_1act_plasma_membrane grey _h_3503 (0) grey _h_5802_1 (0) grey _h_5802_3 (0) grey _h_5802_2 (0) grey _h_5802_4 (0) grey _h_5707 (0) grey _h_523 (0) grey _h_2678 (0) green _h_1737 (0) green _h_4881 (1) _h_5226_1-Ephrin_B2_EPHB1_2_1act_integral_to_membrane _h_5226_2-Ephrin_B2_EPHB1_2_1act_integral_to_membrane p62DOK_1act_2O_plasma_membrane-_h_2585 RB1_E2F1_3_DP_SUV39H1_nucleus_DP1_SUV39H1_E2F1_RB1-_h_2756_2 _h_3048-JNK2_NFAT4_1ina_cytoplasm grey _h_2442 (0) green _h_701 (9) _h_5818-CDK6 grey _h_3372 (0) _h_5813-Ku_Artemis_DNA_PKcs__dimer__POLL_XRCC4__dimer__Ligase_IV_XLF__dimer__site_of_double_strand_break _h_5812-TCF4_beta_catenin_1act_nucleus _h_5812-TLE4_nucleus _h_5817-GDP_v1 _h_5817-RAC1_GTP_1act_cell_leading_edge _h_5816-Ephrin_B1_EPHB1_2_NCK2_1act_integral_to_membrane _h_4118-PIGR _h_5814-TERT green _h_584 (3) grey _h_2315 (0) grey _h_6371 (0) green _h_5267 (1) grey _h_2603 (0) grey _h_3799 (0) _h_1036_14-alpha7_beta1_Integrin_endosome _h_1036_15-alpha9_beta1_Integrin_endosome _h_1036_12-alpha1_beta1_Integrin_endosome _h_1036_13-alpha7_beta1_Integrin_endosome _h_1036_10-alpha8_beta1_Integrin_endosome grey _h_3737_1 (0) grey _h_3737_2 (0) grey _h_264 (0) grey _h_3682 (0) grey _h_878 (0) _h_1036_19-alpha9_beta1_Integrin_endosome _h_3143-Aurora_A_CPEB green _h_458 (2) grey _h_2590 (0) grey _h_2922 (0) alpha6_beta1_Integrin_integral_to_membrane-_h_1036_56 alpha6_beta1_Integrin_integral_to_membrane-_h_1036_54 alpha6_beta1_Integrin_integral_to_membrane-_h_1036_120 alpha6_beta1_Integrin_integral_to_membrane-_h_1036_52 grey _h_5059 (0) alpha6_beta1_Integrin_integral_to_membrane-_h_1036_4 alpha6_beta1_Integrin_integral_to_membrane-_h_1036_104 grey _h_4060 (0) alpha6_beta1_Integrin_integral_to_membrane-_h_1036_88 alpha6_beta1_Integrin_integral_to_membrane-_h_1036_84 alpha6_beta1_Integrin_integral_to_membrane-_h_1036_83 grey _h_3854 (0) grey _h_2813 (0) grey _h_3356 (0) alpha6_beta1_Integrin_integral_to_membrane-_h_1036_135 alpha6_beta1_Integrin_integral_to_membrane-_h_1036_133 grey _h_4796 (0) grey _h_6276 (0) alpha6_beta1_Integrin_integral_to_membrane-_h_1036_98 grey _h_2672 (0) grey _h_4486 (0) _h_3140-GRB2_SOS1_SHC_1act_v1 _h_3147-Ephrin_A5_EPHA3_integral_to_membrane _h_3144-Ephrin_B_EPHB2_Intersectin_N_WASP_1act_dendritic_spine green _h_3897 (0) _h_3148-Ephrin_A1_EPHA4_VSM_RhoGEF_1act_integral_to_membrane grey _h_1379 (0) grey _h_3605 (1) grey _h_166 (0) _h_2620-alpha1_beta1_Integrin_Type_IV_Collagen_integral_to_membrane CaMK_IV-_h_5366 E_cadherin_beta_catenin_early_endosome_v1-_h_4064 green _h_3873 (0) _h_254_5-alpha6_beta4_Integrin_Laminin_14_3_3_hemidesmosome_alpha6_Integrin_Laminin_Gamma_14_3_3_E_Laminin_Alpha_beta4_integrin_1O_Laminin_beta1 grey _h_220 (0) grey _h_3908_1 (0) grey _h_3908_2 (0) _h_2702-I_kappa_B_beta_1ina _h_3044-LEF1_beta_catenin_1act_nucleus_v1 _h_3044-HDAC1_1ina green _h_4077 (0) grey _h_977 (0) grey _h_1301 (0) grey _h_5081 (0) grey _h_4130 (0) grey _h_276 (0) grey _h_2746 (0) grey _h_2245 (0) grey _h_1295 (0) grey _h_3780 (0) grey _h_4139 (0) grey _h_5344 (0) green _h_3605 (0) grey _h_1046 (0) grey _h_4314 (0) grey _h_3452 (0) grey _h_2850 (0) grey _h_2930 (0) grey _h_3016 (0) grey _h_1956 (1) grey _h_6127 (0) grey _h_5029 (0) grey _h_2513 (0) grey _h_6157 (0) grey _h_2949 (0) grey _h_4147 (0) grey _h_659 (0) grey _h_1765 (0) grey _h_5650 (0) _h_2289-Sema4a_Plexin_D1_integral_to_membrane green _h_2786 (0) green _h_198 (0) green _h_156 (1) grey _h_3003_1 (0) green _h_3827 (0) grey _h_3003_4 (0) green _h_644 (0) green _h_4137 (0) green _h_3679 (3) green _h_3333 (0) green _h_3002 (0) green _h_5492 (0) grey _h_2180 (0) grey _h_3423 (0) grey _h_5981 (0) grey _h_4748 (0) _h_1036_106-alphav_beta1_Integrin_endosome red _h_153 (0) SIK2_cytoplasm-_h_1885 grey _h_1404_1 (0) C3G_1ina_cell_cell_junction-_h_5145 grey _h_1393 (0) _h_801-p38_gamma_1O_1O_1act _h_368-FGFR_FGF_Syndecan_2_FRS2_1ina _h_3647-PSA SHC_GRB2_SOS1_1act-_h_4120 _h_1036_24-alpha3_beta1_Integrin_endosome grey _h_2120 (0) beta_Arrestin2-_h_37 grey _h_73_2 (0) grey _h_6093_2 (0) grey _h_3700 (0) green _h_1013 (0) grey _h_2951 (0) grey _h_73_1 (0) green _h_5645 (0) grey _h_1549 (0) grey _h_6093_1 (0) green _h_4129 (20) alpha4_beta1_Integrin_Fibronectin_Paxillin_integral_to_membrane-_h_5496 grey _h_5499 (0) DP5_gene-_h_3696 grey _h_1758 (0) grey _h_2479 (0) MIM_1_gene-_h_5794 MIM_1_gene-_h_2727 MIM_1_gene-_h_1116 MIM_1_gene-_h_5423 Akt1_plasma_membrane-_h_4012 Akt1_plasma_membrane-_h_683 Akt1_plasma_membrane-_h_4789 Prolactin_gene-_h_1879 Prolactin_gene-_h_1934 Prolactin_gene-_h_5653 green _h_1730 (2) _h_4695-CRKL_CBL_C3G green _h_6405 (0) green _h_4956 (0) _h_2541-LPA_LPA3 _h_2542-Alpha_Synuclein_2O_1O_1act_cytoplasm _h_3849-LEWY_BODY _h_4849-PIM1 _h_2545-p21CIP1 _h_2546-IKK_complex_cytoplasm_v2 grey _h_2605 (0) E_cadherin_beta_catenin_alpha_catenin_basolateral_plasma_membrane_v1-_h_243 grey _h_4152 (0) grey _h_4178_1 (0) _h_4970-COL24A1 green _h_5559 (0) grey _h_4581 (0) grey _h_4754 (0) grey _h_5847 (0) grey _h_1247 (0) grey _h_5274 (0) grey _h_5832 (0) grey _h_2607 (0) grey _h_1631 (0) grey _h_4386 (0) grey _h_944 (0) green _h_2212 (0) sELK1-_h_3856 sELK1-_h_933 _h_3263_69-Ca2__v1 _h_3263_69-FGFR1c_FGF5_early_endosome _h_3263_69-alpha_catenin_cytoplasm _h_3263_69-p120_catenin_cytoplasm _h_3263_69-E_cadherin_beta_catenin_early_endosome_v2 _h_4258-GATA1_HDAC4_nucleus grey _h_1963 (0) green _h_4247 (1) Gelsolin-_h_2306 red _h_1117 (4) green _h_5186 (0) green _h_2830 (0) JAK1_1act_2O-_h_4155 GHR_gene-_h_745 ErbB4_CYT2_m80_1act_4O_integral_to_membrane-_h_3894 _h_4253-Metarhodopsin_II_Transducin_1act ADORA2A_gene-_h_4820 _h_4251-NDUFV3 _h_4256-NHE1_1act E_cadherin_beta_catenin_p120ctn_cytoplasmic_vesicle-_h_710 _h_4254-RRAD _h_4255-ELK1_SRF_1act_nucleus_v1 GCK_v1_gene-_h_4605 GCK_v1_gene-_h_5667 green _h_2302 (4) green _h_2704 (5) grey _h_2710 (0) SGK1-_h_876 SGK1-_h_5262 green _h_2017 (0) _h_3825-TXA2_TXA2_R_family_integral_to_membrane green _h_6483 (0) grey _h_2011 (0) grey _h_2552_1 (0) red _h_3913 (0) grey _h_4561_1 (0) RAX-_h_3221 grey _h_6327 (0) _h_4231_1-p38alpha_beta_MAPKAPK2_1act_MAPKAPK2_4O_1O_p38_beta_1O_1O_1act _h_1830_2-FAK_Src_Yes_Fyn_1act_focal_adhesion_v1_Src_1act_1O_FAK_1act_1O grey _h_1446 (0) green _h_972 (0) _h_375-TGF_beta2 ARFGEP100_1ina-_h_2824 red _h_1880 (0) grey _h_1237 (0) grey _h_992 (0) grey _h_3356 (0) grey _h_124 (0) grey _h_2119 (0) grey _h_6255 (0) PI3K_p110_alpha_p55_gamma_1ina-_h_5051_51 PI3K_p110_alpha_p55_gamma_1ina-_h_5051_65 PI3K_p110_alpha_p55_gamma_1ina-_h_2434_33 PI3K_p110_alpha_p55_gamma_1ina-_h_2434_76 PI3K_p110_alpha_p55_gamma_1ina-_h_2434_8 PI3K_p110_alpha_p55_gamma_1ina-_h_5051_66 PI3K_p110_alpha_p55_gamma_1ina-_h_5051_27 PI3K_p110_alpha_p55_gamma_1ina-_h_2434_40 PI3K_p110_alpha_p55_gamma_1ina-_h_5051_21 PI3K_p110_alpha_p55_gamma_1ina-_h_5051_79 PI3K_p110_alpha_p55_gamma_1ina-_h_2434_18 PI3K_p110_alpha_p55_gamma_1ina-_h_2434_44 PI3K_p110_alpha_p55_gamma_1ina-_h_2434_45 PI3K_p110_alpha_p55_gamma_1ina-_h_2434_69 PI3K_p110_alpha_p55_gamma_1ina-_h_5051_14 PI3K_p110_alpha_p55_gamma_1ina-_h_2434_12 PI3K_p110_alpha_p55_gamma_1ina-_h_5051_70 PI3K_p110_alpha_p55_gamma_1ina-_h_5051_20 green _h_6480 (5) green _h_5438 (3) _h_5251-TERT _h_5250-p53__tetramer__nucleus_v3 _h_5252-PUMA _h_5255-ceramide _h_5255-PHOSPHOCHOLINE _h_5257-MYC green _h_335 (131) _h_5258-FLOT2 _h_2264_1-FRS2_family_SHP2_CRK_family_C3G_GAB2_1act_GAB2_FRS2_family_active_1act_Crk_cytoplasm_SHP2_1O_cytoplasm_C3G_1O grey _h_2583 (0) _h_6041-DMT1 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(0) grey _h_1631 (0) grey _h_2151 (0) grey _h_1136 (0) grey _h_1719 (0) alphaM_beta2_Integrin-_h_702 grey _h_4722 (0) grey _h_1971 (0) grey _h_2924 (0) grey _h_5939 (0) grey _h_3406 (0) grey _h_677 (0) grey _h_5334 (0) green _h_291 (5) green _h_5454 (1) grey _h_685 (0) grey _h_6289 (0) _h_2753-CO _h_2753-BILIVERDIN _h_2753-FREE_Fe _h_2020-HP1_alpha green _h_2956 (0) grey _h_2273 (0) grey _h_965 (0) green _h_5382 (0) grey _h_5591 (0) green _h_1252 (1) green _h_704 (1) green _h_2031 (0) green _h_1626 (2) green _h_4288 (2) green _h_3952 (33) green _h_3363 (2) green _h_2450 (20) green _h_1476 (2) grey _h_854_2 (0) grey _h_854_1 (0) grey _h_2719 (0) grey _h_6371 (0) grey _h_5719 (0) FRG_cytoplasm-_h_2550 grey _h_1769 (0) grey _h_4193 (0) grey _h_4332 (0) _h_1226-HPK1_1act_cytoplasm green _h_5993 (0) grey _h_5514 (0) _h_1221-TfR _h_1222-MEF2C_1act_nucleus _h_1223-AR_1ina_1p_cytoplasm _h_1228-Aurora_B_RasGAP_1ina _h_1229-GDP_v1 _h_1229-Dynamin_2_GTP_1act_cell_cell_junction 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green _h_531 (0) green _h_4972 (0) grey _h_5609 (0) _h_2610-DSCAM _h_3263_6-Ca2__v1 _h_3263_6-alpha_catenin_cytoplasm _h_3263_6-p120_catenin_cytoplasm _h_3263_6-FGFR1b_FGF2_early_endosome _h_3263_6-E_cadherin_beta_catenin_early_endosome_v2 grey _h_3654_2 (0) grey _h_3654_5 (0) Smad3_2O_1act_cytoplasm-_h_114 Smad3_2O_1act_cytoplasm-_h_3237 grey _h_5323 (0) _h_3263_5-Ca2__v1 _h_3263_5-alpha_catenin_cytoplasm _h_3263_5-E_cadherin_beta_catenin_early_endosome_v2 _h_3263_5-FGFR1c_FGF4_early_endosome _h_3263_5-p120_catenin_cytoplasm _h_3263_3-Ca2__v1 _h_3263_3-alpha_catenin_cytoplasm _h_3263_3-E_cadherin_beta_catenin_early_endosome_v2 _h_3263_3-FGFR1c_FGF4_early_endosome _h_3263_3-p120_catenin_cytoplasm _h_3263_1-Ca2__v1 _h_3263_1-alpha_catenin_cytoplasm _h_3263_1-FGFR1b_FGF1_early_endosome _h_3263_1-E_cadherin_beta_catenin_early_endosome_v2 _h_3263_1-p120_catenin_cytoplasm Neurotensin_gene-_h_4921 Neurotensin_gene-_h_1459 red _h_5469 (0) grey _h_1574 (0) red _h_2227 (7) grey _h_1819 (0) green _h_2429 (2) green _h_5263 (1) _h_2727-MIM_1 green _h_2903 (0) green _h_260 (0) green _h_3950 (0) green _h_3298 (0) green _h_1067 (1) green _h_4747 (0) Phosphatidic_acid-_h_1630 green _h_725 (0) green _h_2396 (3) green _h_91 (0) _h_319-HES1_TLE1_1act_nucleus _h_316-IL1_alpha_IL1R1_IL1RAP_MYD88_IRAK4_IRAK_TOLLIP_1act_integral_to_membrane _h_317-p35_CDK5 grey _h_5927 (0) grey _h_1780 (0) grey _h_5897 (0) _h_312-EGR2 _h_313-MYC _h_311-Dicer _h_4750-RET51_GFRalpha1_GDNF_SHC_GAB1_Grb2 psoriasin_gene-_h_4501 _h_5929-RELN_LRP8 _h_5929-RELN_VLDLR _h_3578-PLC_beta_2_1act _h_3579-PDGFRB grey _h_1768 (0) grey _h_2911 (1) _h_3575-p14ARF _h_3572-Cortactin_cell_cell_junction _h_3573-JAG2 _h_3570-KIR3DL1 red _h_4739 (0) STX1A_1act-_h_3641 grey _h_4661 (1) grey _h_1764 (0) PDK1_plasma_membrane-_h_6502 PDK1_plasma_membrane-_h_5048 PI3K_beta_plasma_membrane-_h_807_28 PI3K_beta_plasma_membrane-_h_807_52 PI3K_beta_plasma_membrane-_h_807_56 grey _h_2327 (2) PI3K_beta_plasma_membrane-_h_807_71 PI3K_beta_plasma_membrane-_h_807_29 PI3K_beta_plasma_membrane-_h_807_64 PI3K_beta_plasma_membrane-_h_807_74 PI3K_beta_plasma_membrane-_h_760 PI3K_beta_plasma_membrane-_h_807_8 PI3K_beta_plasma_membrane-_h_807_14 Axin1_APC_beta_catenin_cytoplasm-_h_4008 Axin1_APC_beta_catenin_cytoplasm-_h_1093 grey _h_3086 (0) green _h_4263 (0) _h_3953-RFC1__cleaved_ FHL2_gene-_h_1681 _h_1787-FDXR grey _h_3455_1 (0) grey _h_626 (0) green _h_1980 (0) green _h_80 (0) EGFR_1ina-_h_1699 green _h_103 (0) grey _h_5852_2 (0) grey _h_5852_3 (0) grey _h_5852_1 (0) green _h_3267 (1) _h_3782 _h_178_1-JUN_FOSNFAT1_c_4_1act_nucleus_c_Jun_2O_NFATc_1act_nucleus_FOS_1O_1O _h_178_1-JUN_NFAT1_c_4_p21SNFT_1act_nucleus_c_Jun_2O_NFATc_1act_nucleus_p21SNFT _h_178_3-JUN_NFAT1_c_4_p21SNFT_1act_nucleus_c_Jun_2O_NFAT4_1act_nucleus_p21SNFT _h_178_3-JUN_FOSNFAT1_c_4_1act_nucleus_c_Jun_2O_NFAT4_1act_nucleus_FOS_1O_1O _h_178_2-JUN_NFAT1_c_4_p21SNFT_1act_nucleus_c_Jun_2O_NFAT1_1O_7O_2s_1act_nucleus_p21SNFT _h_178_2-JUN_FOSNFAT1_c_4_1act_nucleus_c_Jun_2O_NFAT1_1O_7O_2s_1act_nucleus_FOS_1O_1O grey _h_5627 (0) green _h_5788 (1) grey _h_2951 (0) _h_3506-SDF1 _h_4233_6-Src_1act_1O_integral_to_membrane _h_5834-Crk_p130_Cas_Paxillin_FAK1 _h_5837-Ca2__extracellular_region _h_5837-K___extracellular_region _h_5836-Fyn_1act_1O_plasma_membrane _h_5831-FOXO3A_1O_1ina_1O_cytoplasm _h_5833-alpha10_beta1_Integrin_Type_II_Collagen_integral_to_membrane _h_5832-alphaL_beta2_Integrin_ICAM2_integral_to_membrane _h_4233_1-Yes_1act_1O_integral_to_membrane red _h_1093 (1) green _h_3797 (1) grey _h_4868 (0) _h_6172_4-PRKCG_1act_plasma_membrane STAT1__dimer__1act_nucleus_v5-_h_3285 _h_6172_6-PRKCH_1act_plasma_membrane _h_6172_7-PKC_delta_1act_plasma_membrane _h_6172_1-PKC_epsilon_1act_plasma_membrane _h_6172_2-PKC_isoenzymes_1act_plasma_membrane _h_6172_3-PKC_theta_1act_plasma_membrane grey _h_4139 (0) grey _h_2260 (0) green _h_890 (1) IKKs_gene-_h_4421 green _h_4856 (0) _h_3168-BCL2_1O EGFR_EGFR_integral_to_membrane-_h_4664 _h_3574 green _h_4962 (0) _h_3167-PIP3_plasma_membrane _h_3166-RAB5_GDP_GDI1_1ina_cytoplasm green _h_3235 (10) _h_1784-Cathepsin_D _h_6096-NDEL1_14_3_3_E green _h_6128 (0) green _h_976 (1) DAPK1_gene-_h_123 _h_5101-HEY1_RBPJ _h_5101-NICD_1O _h_5374-ARG1 grey _h_3742 (0) grey _h_4747 (0) grey _h_5796 (0) _h_3581_1-JUNB_Fra1_NFAT1_c_4_1act_nucleus_NFAT4_1act_nucleus_Fra1_JUNB green _h_5947 (0) green _h_855 (0) green _h_5352 (0) green _h_2117 (2) green _h_5438 (4) green _h_3225 (1) green _h_4908 (0) green _h_5856 (0) green _h_6047 (1) green _h_2422 (0) green _h_6480 (8) green _h_6188 (4) green _h_6095 (0) _h_3581_2-JUNB_Fra1_NFAT1_c_4_1act_nucleus_NFATc_1act_nucleus_Fra1_JUNB TOM1_gene-_h_2854 green _h_5333 (0) green _h_5116 (1) green _h_1269 (1) green _h_1204 (1) green _h_763 (0) green _h_5030 (7) green _h_2190 (1) green _h_2805 (1) green _h_4128 (1) green _h_2202 (1) green _h_2323 (1) green _h_4148 (1) green _h_5980 (1) green _h_4982 (0) green _h_320 (4) green _h_253 (1) green _h_2420 (1) green _h_4378 (7) green _h_4468 (2) green _h_248 (2) green _h_3313 (7) green _h_3268 (7) green _h_5511 (0) green _h_2953 (1) green _h_6402 (1) green _h_6423 (1) green _h_5403 (1) green _h_6406 (1) green _h_6136 (1) green _h_4959 (1) green _h_1683 (1) green _h_1745 (1) green _h_2373 (4) green _h_3118 (0) _h_5430-MYC_Max_nucleolus _h_1621_2-IL2_IL2R_alpha_beta_gamma_JAK1_LCK_JAK3_IRS1_2_1act_integral_to_membrane green _h_2971 (0) _h_4265-PDGF_BB_PDGFRB__dimer__1ina_integral_to_membrane _h_6101-NOTCH1_heterodimer_late_endosome _h_3505-Smad3_MYC_1act FOXO1_14_3_3_family_nucleus_v2_YWHAB_FOXO1_1O_2O-_h_2760_4 _h_1036_39-alpha11_beta1_Integrin_endosome green _h_4568 (0) _h_1036_30-alpha9_beta1_Integrin_endosome _h_1036_31-alpha4_beta1_Integrin_endosome green _h_5500 (0) green _h_5738 (0) _h_1036_33-alpha9_beta1_Integrin_endosome _h_1036_34-alpha2_beta1_Integrin_endosome _h_1036_35-alpha7_beta1_Integrin_endosome _h_1036_36-alpha10_beta1_Integrin_endosome Alpha_Synuclein_1O_cytoplasm-_h_2542 _h_1698 Alpha_Synuclein_1O_cytoplasm-_h_664 Alpha_Synuclein_1O_cytoplasm-_h_1124 Alpha_Synuclein_1O_cytoplasm-_h_1267 grey _h_3527 (0) grey _h_522 (0) grey _h_732 (0) Alpha_Synuclein_1O_cytoplasm-_h_6323 grey _h_3086 (0) grey _h_4769 (0) green _h_5822 (0) green _h_3039 (0) green _h_5793 (0) red _h_1203 (0) grey _h_5447 (0) green _h_1696 (0) green _h_2661 (0) green _h_1864 (0) red _h_3405 (0) green _h_374 (0) green _h_6237 (0) BRAF_1ina_cytoplasm-_h_349 grey _h_6104 (0) BRAF_plasma_membrane-_h_6345 _h_117-CaM_Ca2_ green _h_3608 (0) green _h_1207 (1) _h_569-PKC_epsilon_1act_cytoplasm _h_5432-Ca____cytoplasm _h_2569-CRTC2_1ina_1O_cytoplasm Stathmin-_h_2047 Stathmin-_h_3863 _h_2563-Cyclin_E1 _h_2560-CXCL9 green _h_3340 (0) _h_2070_1 _h_2070_1 _h_2397-BAD_1act_cytoplasm _h_2729-HGF_dimer__MET_dimer__1act_endosome _h_2565-DNTT Myeloperoxidase_gene-_h_1119 Myeloperoxidase_gene-_h_2728 _h_1243-GMCSF_GMR_alpha_CSF2RB_JAK2__dodecamer__SHP2_1act_integral_to_membrane grey _h_1746 (0) _h_2391-PTP1B _h_2604-IL10_extracellular_region green _h_4631 (3) green _h_5222 (0) grey _h_1867 (0) green _h_1329 (1) grey _h_1662 (0) _h_5465_1-MSK1_1act PLA2_Group_4A_gene-_h_3461 PI3K_Class_IA_cytoplasm-_h_904 TfR_gene-_h_4946 TfR_gene-_h_1221 TfR_gene-_h_4550 green _h_5252 (4) green _h_2461 (8) green _h_3843 (8) green _h_3549 (4) green _h_2413 (0) green _h_735 (7) _h_1240-mTORC1_PRAS40_DEPTOR_PML_1ina_perinuclear_region_of_cytoplasm grey _h_4599 (0) green _h_4965 (2) green _h_5673 (0) green _h_431 (0) green _h_4626 (2) _h_4886_1-CXCL4_CXCR3_B_integral_to_membrane _h_4886_1-CXCL9_11_CXCR3_B_integral_to_membrane A_FABP_gene-_h_5887 green _h_3917 (0) green _h_5031 (13) grey _h_2243 (0) _h_1140-NPC_RanGAP1_SUMO1 green _h_4779 (0) grey _h_444 (0) grey _h_607 (0) Angiotensin_II_v1_gene-_h_1706 SCF_ubiquitin_ligases_gene-_h_2839 p53_1O-_h_5740 _h_3511-DAPK1_1act FOXP3_gene-_h_219 TFF1_v2_gene-_h_5357 TFF1_v2_gene-_h_622 TFF1_v2_gene-_h_1147 TFF1_v2_gene-_h_1149 TFF1_v2_gene-_h_4666 TFF1_v2_gene-_h_666 TFF1_v2_gene-_h_1103 TFF1_v2_gene-_h_3623 grey _h_4874 (0) _h_3901-PTCH1_integral_to_membrane green _h_4519_2 (1) green _h_4519_1 (1) green _h_3446 (1) green _h_42 (1) green _h_2840 (1) green _h_6292 (0) green _h_5671 (0) green _h_5992 (2) green _h_4553 (1) green _h_2510 (1) green _h_6355 (1) green _h_2249 (1) green _h_2854 (1) green _h_1309 (2) green _h_5688 (1) grey _h_6447_1 (0) _h_5436-E4ICDs_1act_5O_cytoplasm green _h_802 (0) green _h_5409 (0) red _h_1641 (0) ID1_gene-_h_4953 ID1_gene-_h_1371 ID1_gene-_h_2822 _h_2239_1-PER1_2___WDR5 _h_5239-MCL1 _h_5238-p14ARF _h_4059_2-JNK2_1O_1O_1act _h_4983-IGF_1R_heterotetramer_IGF1 _h_1142-CBL_CRKL_GRB2_1act_cytoplasm red _h_1078 (1) green _h_4601 (3) grey _h_6300 (0) _h_3654_1-Src_family_SYK_family_BLNK_LAT_BTK_ITK_1act_SYK_Family_Kinases_active_1act_BTK_ITK_active_1act_LAT_10O_1act_Fyn_1O_1act _h_5236-CSK_PAG1_1act 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_h_4059_2 (8) green _h_4528_2 (2) green _h_4528_1 (2) green _h_4059_1 (8) HPK1_cytoplasm-_h_1226 _h_331-MYC_Max_MIZ_1_nucleus _h_331-MIZ_1_p300_nucleus _h_332-DBS_1act_1O _h_2894_16-FOXO1_3a_4_14_3_3_family_1ina_cytoplasm_FOXO1_3a_4_inactive_1ina_YWHAZ _h_2637_9-PI3K_p110_delta_p85_beta_1act_plasma_membrane _h_335-Erk2_1O_1O_1act _h_336-Caveolin_1_1ina _h_337-EIF2A_14_3_3_E_1act grey _h_2710 (0) SMAD2_2O_1act_cytoplasm-_h_855 grey _h_13 (0) grey _h_350 (0) SMAD2_2O_1act_cytoplasm-_h_4985 SMAD2_2O_1act_cytoplasm-_h_4600 _h_2894_18-FOXO1_3a_4_14_3_3_family_1ina_cytoplasm_YWHAB_FOXO1_3a_4_inactive_1ina _h_5585-Axin2 _h_3519-FAK_1act_1O IL4R_gene-_h_5612 IL4R_gene-_h_4324 _h_5586-glucose_intracellular _h_5580-ARG1 green _h_2973 (0) grey _h_4833 (0) _h_3510-IGFBP1 grey _h_4691 (0) grey _h_1540 (0) grey _h_3798 (0) grey _h_4131 (0) grey _h_3324 (0) grey _h_2764 (0) grey _h_5778 (0) grey _h_5903 (0) grey _h_1519 (0) _h_5589-IL8 _h_5588-STAP1_1act _h_3516-LAT_GRAP2_SLP76_ADAP_1act_integral_to_membrane _h_3517-Nemo_like_kinase_1act green _h_4832 (0) _h_4738-GRG4 _h_719-TMPRSS2 green _h_6337_3 (1) green _h_6337_2 (1) green _h_6337_1 (1) _h_3315-alpha4_beta1_Integrin_Thrombospondin_integral_to_membrane green _h_1680 (1) grey _h_2924 (0) grey _h_5369 (0) Crk_cell_cell_junction-_h_2836 _h_2434_30-PI3K_p110_alpha_p85_beta_1act_plasma_membrane grey _h_3505 (0) grey _h_5917 (0) grey _h_3041 (0) _h_2434_33-PI3K_p110_alpha_p85_beta_1act_plasma_membrane _h_2434_32-PI3K_delta_1act_plasma_membrane grey _h_4271 (0) green _h_6355 (4) green _h_3309 (2) green _h_1485 (0) green _h_2738 (1) TRX_ASK1_1ina-_h_363 grey _h_5979 (0) grey _h_5535 (0) CITED2_gene-_h_2212 CITED2_gene-_h_3345 LC20-_h_5184 green _h_717 (0) grey _h_3457 (0) green _h_353_2 (0) green _h_5443 (0) PKC_zeta_1act-_h_3369_1 green _h_353_1 (0) _h_2434_36-PI3K_1act_plasma_membrane_v2 _h_2469-alpha2_beta1_Integrin_Type_XI_Collagen_integral_to_membrane grey _h_3220 (0) _h_214-KSR_v1 grey _h_4777 (0) green _h_4529 (3) grey _h_657_3 (0) grey _h_657_2 (0) grey _h_657_1 (0) green _h_5545 (0) _h_3911-IFN_gamma_extracellular_region _h_3433-WAVE1 green _h_1798 (2) green _h_2441 (1) green _h_1850 (1) _h_4290_2-GNAL_1act grey _h_6438_2 (0) p130Cas-_h_4706 grey _h_146 (0) p130Cas-_h_1793 grey _h_3015 (7) grey _h_6438_1 (0) grey _h_981 (0) grey _h_33 (5) grey _h_4712 (0) grey _h_277 (0) p130Cas-_h_3739 p130Cas-_h_1388 grey _h_1466 (0) p130Cas-_h_2941 p130Cas-_h_164 grey _h_175 (0) grey _h_3377 (0) C3G_cytoplasm-_h_2251 grey _h_5946 (0) grey _h_6203 (0) Mena-_h_5709 Mena-_h_6183 _h_5352-Jnk1_1O_1act_1O_nucleus green _h_4366 (0) green _h_2543 (0) Erk1_1O_1act_1O_nucleus-_h_2799_1 grey _h_4264_2 (0) green _h_2983 (0) green _h_508 (0) green _h_5675 (0) green _h_2791 (0) green _h_821 (0) green _h_359 (0) green _h_1958 (0) green _h_3052 (0) green _h_1122 (0) _h_861-HST green _h_3280 (1) grey _h_1812 (0) _h_4982-IL2_extracellular_region AP_24-_h_3974 AP_24-_h_5234 _h_4980-Activin_A_ACTR2_Endoglin__dimer__1act_integral_to_membrane _h_4981-STAT3_STAT4_1act_integral_to_membrane _h_4986-Caspase_8_1O_1act_cytoplasm _h_4986-FADD c_FLIPS_gene-_h_1922 _h_4984-TAp73b__tetramer__1ina_cytoplasm _h_4988-IFN_gamma_extracellular_region _h_4989-Beta_Casein KSR_14_3_3_KSR1_1ina_1O_YWHAZ-_h_5015_5 _h_948 _h_1100-NRIF_2u_nucleus _h_1100-Sortilin_TRAF6_extracellular_region grey _h_2755 (0) grey _h_3977 (0) _h_3453-BNIP3L HBP1_gene-_h_1900 HBP1_gene-_h_2630 green _h_5935 (0) green _h_3396 (0) green _h_1972 (0) grey _h_3560 (0) _h_1309-TTR green _h_3819 (0) green _h_5487 (0) _h_863-sDelta_1_1act _h_1103-TFF1_v2 red _h_5154 (3) grey _h_315 (0) TC10_GDP-_h_4435 green _h_1755 (1) TCPTP_p45_cytoplasm-_h_5169 green _h_1181 (0) green _h_5473 (0) grey _h_887 (0) grey _h_5031 (14) grey _h_2633 (0) grey _h_6498 (1) GTP_v1-_h_5663 grey _h_5668 (0) grey _h_4658 (0) grey _h_4129 (25) grey _h_976 (2) grey _h_6344 (2) grey _h_1425 (3) grey _h_6403_1 (10) grey _h_3797 (2) grey _h_5543 (1) grey _h_6403_2 (10) grey _h_5948 (0) grey _h_3126 (0) grey _h_341 (2) grey _h_5998 (0) grey _h_4216 (0) grey _h_3760 (5) grey _h_1611_2 (3) grey _h_4178_1 (0) grey _h_4178_2 (0) grey _h_1229 (0) grey _h_4111 (49) grey _h_163 (0) grey _h_4242 (1) grey _h_5181 (1) grey _h_4296 (0) grey _h_3568 (5) grey _h_5420 (5) grey _h_1452 (0) grey _h_968 (0) grey _h_5817 (1) grey _h_2536 (3) grey _h_370 (0) grey _h_4260 (1) grey _h_701 (36) grey _h_4181 (0) grey _h_499 (2) grey _h_6080 (0) grey _h_4062 (0) grey _h_26 (0) grey _h_25 (0) grey _h_6476 (0) grey _h_2919 (0) grey _h_1174 (0) grey _h_3952 (43) grey _h_5209 (0) grey _h_783 (1) grey _h_785 (0) grey _h_5367 (0) grey _h_4833 (0) grey _h_3398 (0) grey _h_4831 (4) grey _h_1289 (1) grey _h_4678 (0) grey _h_1368 (0) grey _h_5390 (0) grey _h_330 (1) grey _h_2478 (0) grey _h_1308 (0) grey _h_5741 (0) grey _h_4761 (6) grey _h_6144 (0) grey _h_232 (0) grey _h_3160 (0) grey _h_3216 (0) grey _h_5821 (1) grey _h_1773 (0) grey _h_2498_1 (1) grey _h_2498_2 (1) grey _h_5985 (3) grey _h_4169 (0) grey _h_5279 (0) grey _h_1215_2 (2) grey _h_1215_1 (2) grey _h_6305 (0) grey _h_1462 (0) grey _h_6400 (0) grey _h_2449 (1) grey _h_3872 (0) grey _h_5990 (0) grey _h_3460 (0) grey _h_4463 (0) grey _h_5264 (0) grey _h_3205 (0) grey _h_1611_1 (3) grey _h_1557 (0) grey _h_3531 (0) grey _h_2372 (0) grey _h_3907 (0) grey _h_3906 (0) grey _h_458 (3) grey _h_1329 (2) grey _h_6169 (2) grey _h_6164 (0) grey _h_4783 (0) grey _h_2053 (6) grey _h_4707 (10) grey _h_3235 (30) grey _h_4381 (0) grey _h_3347 (7) grey _h_4905 (1) grey _h_919 (5) grey _h_4987 (0) grey _h_4865 (9) grey _h_3933 (0) grey _h_3930 (0) grey _h_2189 (0) grey _h_1434 (1) grey _h_6357 (0) grey _h_2213 (0) grey _h_5400 (0) grey _h_3117 (0) grey _h_4135 (0) grey _h_2750 (7) grey _h_1245 (0) grey _h_3791 (0) red _h_3403 (3) red _h_4912 (1) _h_6353-HMGB1_TLR2_TLR1_MYD88_TIRAP_1act_integral_to_membrane _h_1813_3-NFAT1_c_4__dimer__EGR4_NFAT4_1act_nucleus_EGR4_nucleus _h_5309_7-alpha6_beta4_Integrin_Laminin_hemidesmosome _h_1813_2-NFAT1_c_4__dimer__EGR4_NFATc_1act_nucleus_EGR4_nucleus grey _h_29_1 (0) grey _h_29_3 (0) grey _h_29_2 (0) red _h_741 (0) grey _h_29_4 (0) grey _h_3567_4 (0) grey _h_4241 (1) grey _h_1129 (0) grey _h_3567_3 (0) grey _h_3567_2 (0) grey _h_2194 (0) grey _h_4748 (0) grey _h_2175_3 (0) grey _h_2175_2 (0) grey _h_3105 (0) grey _h_2175_4 (0) green _h_3947 (0) grey _h_2175_1 (0) grey _h_2288 (0) grey _h_3567_1 (0) grey _h_3338 (0) grey _h_966 (0) grey _h_3445 (0) grey _h_1219_2 (1) grey _h_1219_1 (1) green _h_299 (0) grey _h_2303 (0) grey _h_1959_1 (0) grey _h_1959_2 (0) _h_4540_1-PARP1_fragment_1_1ina PEPCK_gene-_h_3005 grey _h_4868 (0) betaPIX-_h_4954 grey _h_2267 (0) _h_4540_2-PARP1_fragment_2_1ina eIF4B-_h_3948 MEK2-_h_5131_2 grey _h_3613 (0) MEK2-_h_2114 _h_1916-LAT_GRAP2_SLP76_VAV1_PI3K_Class_IA_1act green _h_3929 (1) _h_1362 grey _h_4036 (0) green _h_725 (2) _h_1766 _h_3435-PEA3_1O green _h_4707 (8) grey _h_4385 (0) green _h_5663 (2) green _h_5663 (0) green _h_4707 (4) grey _h_3198 (0) grey _h_1431 (0) grey _h_4234 (0) grey _h_1989 (1) grey _h_2436 (0) _h_2005_3-uPAR_DII_DIII_fMLP_receptors_integral_to_membrane grey _h_1283 (0) carboxylesterase_gene-_h_247 green _h_3539 (0) PLA2_Group_4A-_h_2665 PLA2_Group_4A-_h_4443 PLA2_Group_4A-_h_832 _h_3638-SMAD1_SMAD1_SMAD4_1act_nucleus green _h_3606 (0) _h_1813_1-NFAT1_c_4__dimer__EGR4_NFAT1_1O_7O_2s_1act_nucleus_EGR4_nucleus green _h_2450 (9) PHD3_gene-_h_3395 grey _h_4931 (0) NFAT4_gene-_h_318 grey _h_53 (0) green _h_1974 (0) grey _h_1993 (0) green _h_2231 (1) grey _h_3804 (0) green _h_2404 (2) GLUT3_gene-_h_6398 grey _h_912 (0) _h_4294-NFAT1_1O_4O_1act_nucleus FGFR1c_FGF2_plasma_membrane-_h_2944_79 FGFR1c_FGF2_plasma_membrane-_h_2944_81 FGFR1c_FGF2_plasma_membrane-_h_2944_24 FGFR1c_FGF2_plasma_membrane-_h_2944_57 FGFR1c_FGF2_plasma_membrane-_h_2944_23 FGFR1c_FGF2_plasma_membrane-_h_2944_45 FGFR1c_FGF2_plasma_membrane-_h_2944_73 green _h_3021 (6) grey _h_4011_9 (0) grey _h_1636_2 (0) FGFR1c_FGF2_plasma_membrane-_h_2944_17 grey _h_2003_3 (0) FGFR1c_FGF2_plasma_membrane-_h_2944_30 grey _h_272 (0) _h_58-Rhodopsin_1ina _h_5215-SPATA18 _h_5214-E2F1_DP_TopBP1_nucleus _h_5217-alpha6_beta4__cleaved__Integrin_Laminin_hemidesmosome _h_5216-p47_Phox_p67_Phox_cytochrome_b_245_integral_to_membrane _h_5211-GLUT1 grey _h_1596 (0) green _h_505 (4) _h_143-alpha1_beta1_Integrin_TCPTP_p45_integral_to_membrane _h_2175_1-RARs_AIB1_Cbp_p300_PCAF_9cRA_1act_AIB1_PCAF_CBP_RAR_alpha_9cRA BoNT_C1_precursor-_h_6486 _h_5218-DFFB_1act_cytoplasm _h_5218-ICAD__cleaved__1ina SOCS3_gene-_h_2412 SOCS3_gene-_h_4524 SOCS3_gene-_h_4394 SOCS3_gene-_h_4719 SOCS3_gene-_h_2899 green _h_4111 (30) _h_1109-PLK1_1ina_centrosome _h_1051-TCF4E_beta_catenin_BCL9_1act_nucleus _h_6006-TGFB_TGFBR2_TGFBR1_PPP2R2A_1act_integral_to_membrane green _h_1106 (2) green _h_5151 (3) _h_6000-SALL4 _h_1055-IL2_IL2R_alpha_beta_gamma_JAK1_LCK_JAK3_SHC_1act_integral_to_membrane _h_6002-CD98 GLUT4_cytoplasm-_h_6056 green _h_5524 (0) _h_1058-STAT6__cleaved_dimer__nucleus_v2 _h_6009-HIF2A_ARNT_nucleus_v1 green _h_701 (3) grey _h_2767 (0) grey _h_301 (0) _h_3576-PML _h_3576-TAp73a__tetramer__nucleus_v4 _h_462-FAK_Paxillin_1act _h_4461-PAK1_1p_dendritic_spine IL8_gene-_h_4762 IL8_gene-_h_1104 IL8_gene-_h_2679 IL8_gene-_h_3702 IL8_gene-_h_5589 _h_4594_2-BRAF_14_3_3_1ina_plasma_membrane_BRAF_3O_4O_YWHAG _h_4594_2-RAF1_14_3_3_1ina_plasma_membrane_RAF1_1O_8O_YWHAG RANBP1_gene-_h_2271 _h_3745-SUMO1_HDAC4_cytoplasm_v2 _h_3745-Ran_GTP_Exportin_1_cytoplasm SMARCD3_gene-_h_4149 _h_3747-RET9_GFRalpha1_GDNF _h_3746-Cyclin_D1 _h_3740-Erk2_1O_1O_1act_cytoplasm _h_3743-PSA green _h_4111 (26) green _h_3235 (18) _h_4594_1-BRAF_14_3_3_1ina_plasma_membrane_BRAF_3O_4O_14_3_3_E _h_4594_1-RAF1_14_3_3_1ina_plasma_membrane_RAF1_1O_8O_14_3_3_E RAF1_1O-_h_4990 OSM_v1_gene-_h_5046 OSM_v1_gene-_h_3826 _h_6229_6-p27Kip1_KPNA1_1act _h_6229_6-p27Kip1_14_3_3_family_1ina_cytoplasm_14_3_3_E_p27Kip1_1O RHOA-_h_5928 RHOA-_h_1326 _h_6229_4-p27Kip1_14_3_3_family_1ina_cytoplasm_YWHAG_p27Kip1_1O _h_6229_4-p27Kip1_KPNA1_1act _h_6229_3-p27Kip1_14_3_3_family_1ina_cytoplasm_p27Kip1_1O_YWHAS _h_6229_3-p27Kip1_KPNA1_1act grey _h_2694 (0) _h_6229_1-p27Kip1_14_3_3_family_1ina_cytoplasm_p27Kip1_1O_YWHAQ _h_6229_1-p27Kip1_KPNA1_1act grey _h_1985 (0) grey _h_1804 (0) green _h_5802_3 (0) green _h_5802_2 (0) green _h_5802_4 (0) green _h_1277 (8) green _h_716 (1) green _h_5802_1 (0) green _h_2400 (0) green _h_135 (14) green _h_3191 (1) green _h_4636 (0) green _h_3054 (2) green _h_2206 (0) green _h_5295 (0) Caspase_7_gene-_h_2444 _h_4594_4-RAF1_14_3_3_1ina_plasma_membrane_RAF1_1O_8O_YWHAZ _h_4594_4-BRAF_14_3_3_1ina_plasma_membrane_BRAF_3O_4O_YWHAZ grey _h_2031 (1) grey _h_1252 (1) green _h_1530 (0) grey _h_4331 (0) _h_1089-TSHR_integral_to_membrane grey _h_2005_3 (0) grey _h_2005_2 (0) grey _h_2005_1 (0) grey _h_5093 (0) _h_1687-p47_Phox_p67_Phox_cytochrome_b_245_RAC1_GTP_integral_to_membrane _h_2959-EPO_extracellular_region RR2_gene-_h_1504 _h_4663-Calcineurin_A_alpha_beta_B1_DSCR1L1_1ina ET2_gene-_h_3868 green _h_5699 (1) _h_3777-XRCC1 green _h_872 (0) _h_6221_4-AMPKK2_active_1act_cytoplasm green _h_1489 (0) green _h_4122 (1) green _h_3690 (0) green _h_4412 (0) green _h_3957 (0) green _h_3318 (0) green _h_3997 (1) green _h_1699 (0) E_cadherin_Ca2__beta_catenin_gamma_catenin_alpha_catenin_p120_catenin_cell_cell_junction_v1-_h_2559_1 E_cadherin_Ca2__beta_catenin_gamma_catenin_alpha_catenin_p120_catenin_cell_cell_junction_v1-_h_3069 E_cadherin_Ca2__beta_catenin_gamma_catenin_alpha_catenin_p120_catenin_cell_cell_junction_v1-_h_2559_2 E_cadherin_Ca2__beta_catenin_gamma_catenin_alpha_catenin_p120_catenin_cell_cell_junction_v1-_h_40_2 E_cadherin_Ca2__beta_catenin_gamma_catenin_alpha_catenin_p120_catenin_cell_cell_junction_v1-_h_40_1 _h_456_3-MKK4_fragment_2_1ina_cytoplasm green _h_1626 (0) green _h_4288 (0) green _h_3952 (23) green _h_3363 (0) green _h_2450 (29) green _h_1476 (0) XRCC4_nucleus-_h_2146 _h_4164-p27Kip1_1O _h_4165-MCM4 _h_4166-eIF2A_1ina _h_4160-BDNF__dimer__TRKB_1act_integral_to_membrane_v1 _h_4161-MEK1_3O_1act _h_4590-CDC42_GTP_IQGAP1_filamentous_actin_cell_cell_junction _h_2953-IFN_gamma_extracellular_region green _h_2975 (0) green _h_6024 (0) _h_4168-MMP2 _h_4169-GDP_v1 _h_4169-CDC42_GTP_1act_dendritic_spine grey _h_23 (0) _h_142-Lck_1ina green _h_1291 (0) green _h_6488 (0) green _h_2085 (4) green _h_4782 (0) _h_2951-betaglycan_beta_Arrestin2_1ina_endosome green _h_468 (0) GM1-_h_4911 _h_2950-TAp63a__tetramer__p14ARF_1ina_nucleus _h_3263_47-Ca2__v1 _h_3263_47-alpha_catenin_cytoplasm _h_3263_47-E_cadherin_beta_catenin_early_endosome_v2 _h_3263_47-FGFR1c_FGF4_early_endosome _h_3263_47-p120_catenin_cytoplasm red _h_5900 (0) grey _h_3073 (0) MDM2_UBCH5_v2-_h_5698 grey _h_2221 (0) green _h_623 (0) green _h_3066 (1) _h_455_6-RAF1_BRAF_14_3_3_14_3_3_1act_plasma_membrane_v2_RAF1_1O_3O_BRAF_1O_2O_YWHAS PLK3_gene-_h_463 green _h_4464 (0) 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_h_3263_2-E_cadherin_beta_catenin_early_endosome_v2 _h_5861_2-SMAD2_3_SMAD4_FOXO1_3a_4_1act_nucleus_v2_SMAD2_2O_1act_FOXO1_3a_4_1act_SMAD4 _h_5861_2-SMAD2_3_SMAD4_FOXO1_3a_4_FOXG1_1act_nucleus_SMAD2_2O_1act_FOXO1_3a_4_1act_FOXG1_SMAD4 _h_3230-IL6_IL6RA_gp130__dimer__JAK2_JAK2_LMO4_1act_integral_to_membrane _h_2915 p47_Phox_p67_Phox-_h_1411 _h_5199_2-JUN_JUN_FOS_RACO_1_1act_nucleus_JUN_RACO_1 green _h_503 (0) grey _h_4206 (0) _h_4606-Eps8_ABI1_SOS1_v1 _h_4606-RNTRE_1ina _h_2954 TRKA_gene-_h_1666 TRKA_gene-_h_5987 PA26_gene-_h_2826 _h_4976-p13_BID_cytoplasm _h_4976-p11_BID_cytoplasm _h_4976-p15_BID_cytoplasm _h_2084_2-CDC25B_14_3_3_family_YWHAG_CDC25B_1O _h_2084_3-CDC25B_14_3_3_family_14_3_3_E_CDC25B_1O PI3K_p110_delta_p55_gamma_1ina-_h_2434_31 PI3K_p110_delta_p55_gamma_1ina-_h_5051_42 PI3K_p110_delta_p55_gamma_1ina-_h_5051_2 PI3K_p110_delta_p55_gamma_1ina-_h_5051_45 PI3K_p110_delta_p55_gamma_1ina-_h_2434_36 PI3K_p110_delta_p55_gamma_1ina-_h_5051_11 PI3K_p110_delta_p55_gamma_1ina-_h_5051_56 PI3K_p110_delta_p55_gamma_1ina-_h_5051_9 PI3K_p110_delta_p55_gamma_1ina-_h_5051_43 PI3K_p110_delta_p55_gamma_1ina-_h_2434_41 PI3K_p110_delta_p55_gamma_1ina-_h_2434_55 PI3K_p110_delta_p55_gamma_1ina-_h_2434_78 PI3K_p110_delta_p55_gamma_1ina-_h_2434_51 PI3K_p110_delta_p55_gamma_1ina-_h_5051_30 PI3K_p110_delta_p55_gamma_1ina-_h_2434_13 PI3K_p110_delta_p55_gamma_1ina-_h_2434_11 PI3K_p110_delta_p55_gamma_1ina-_h_2434_62 PI3K_p110_delta_p55_gamma_1ina-_h_5051_17 red _h_2217 (8) grey _h_3186 (0) _h_2084_4-CDC25B_14_3_3_family_YWHAZ_CDC25B_1O _h_4974-BoNT_F_Light_Chain_endosome PRDM15_gene-_h_5096 PRDM15_gene-_h_3541 _h_4067-Ephrin_B_EPHB1_Src_1act_integral_to_membrane _h_2446 NOTCH1_Golgi_apparatus-_h_5721 green _h_2741_1 (0) _h_2399-netrin_1_UNC5C_1act_integral_to_membrane _h_954-AP1B1 _h_4971-Caspase_8_cytoplasm grey _h_4296 (0) _h_6226-ZEB1 Akt1_1O_1act_1O_1O_cytoplasm-_h_5982 _h_5192-FOXO3A_1O_1O_nucleus Granzyme_B_gene-_h_3681 Granzyme_B_gene-_h_6034 Jnk1_nucleus-_h_1015 _h_957-HSF1 grey _h_1171_2 (0) grey _h_4994 (0) grey _h_1171_1 (0) grey _h_358 (0) grey _h_1346 (0) grey _h_2912 (0) grey _h_1627 (0) grey _h_1799 (0) grey _h_3612 (0) _h_2385_4 _h_4393_2 _h_4393_4 _h_853 _h_5455_1-beta_catenin_cytoplasm _h_5455_1-APC _h_5455_1-WNT3A_LRP6_FZD5_DVL_Axin1_GSK3_1act_integral_to_membrane_v2_FZD5_DVL2_WNT3A_2N_1S_1O_GSK3A_LRP6_1O_1O_Axin1 _h_5455_2-beta_catenin_cytoplasm _h_5455_2-APC _h_5455_2-WNT3A_LRP6_FZD5_DVL_Axin1_GSK3_1act_integral_to_membrane_v2_FZD5_DVL2_WNT3A_2N_1S_1O_LRP6_1O_1O_GSK3beta_Axin1 green _h_1865 (0) grey _h_1287 (0) grey _h_1418 (0) grey _h_5191 (0) grey _h_3980 (0) grey _h_3470 (0) green _h_4865 (8) red _h_3638 (0) CDK2_cytoplasm-_h_1341 green _h_477 (2) green _h_3359 (0) grey _h_4983 (0) grey _h_772 (0) grey _h_5563 (1) _h_4120-p52_SHC_1ina_2O _h_4120-GRB2_SOS1_v2 TIGAR_gene-_h_294 _h_4124-Aurora_A_NDEL1_TACC3_centrosome _h_4125-uPA_uPAR_alphav_beta3_Integrin_integral_to_membrane _h_4126-Akt1_1O_1act_v2 _h_2894_1-FOXO1_3a_4_14_3_3_family_1ina_cytoplasm_FOXO1_3a_4_inactive_1ina_YWHAZ _h_2894_3-FOXO1_3a_4_14_3_3_family_1ina_cytoplasm_14_3_3_E_FOXO1_3a_4_inactive_1ina _h_2894_5-FOXO1_3a_4_14_3_3_family_1ina_cytoplasm_YWHAG_FOXO1_3a_4_inactive_1ina _h_2894_4-FOXO1_3a_4_14_3_3_family_1ina_cytoplasm_14_3_3_E_FOXO1_3a_4_inactive_1ina _h_2894_7-FOXO1_3a_4_14_3_3_family_1ina_cytoplasm_FOXO1_3a_4_inactive_1ina_YWHAQ _h_2894_6-FOXO1_3a_4_14_3_3_family_1ina_cytoplasm_FOXO1_3a_4_inactive_1ina_YWHAQ _h_2894_9-FOXO1_3a_4_14_3_3_family_1ina_cytoplasm_FOXO1_3a_4_inactive_1ina_YWHAZ _h_2894_8-FOXO1_3a_4_14_3_3_family_1ina_cytoplasm_YWHAG_FOXO1_3a_4_inactive_1ina green _h_6145 (0) Hck_1ina-_h_1043_2 TFF3_extracellular_region_gene-_h_693 _h_2872-TAp63b _h_2873-PITX2 green _h_701 (16) _h_2876-MMP9 grey _h_4018 (0) grey _h_1759_3 (0) grey _h_1759_1 (0) grey _h_3210_1 (0) grey _h_5226_1 (0) grey _h_1759_2 (0) green _h_1223 (0) grey _h_2317 (0) grey _h_5349 (0) grey _h_3709_3 (0) _h_4806_3-S1P1_S1P_Gi_1act_GNAO1_1act_S1P1_1act_S1P_extracellular_region _h_4806_1-S1P1_S1P_Gi_1act_GNAI3_1act_S1P1_1act_S1P_extracellular_region _h_807_51-PI3K_p110_alpha_p85_beta_1act_plasma_membrane _h_4806_4-S1P1_S1P_Gi_1act_GNAZ_1act_S1P1_1act_S1P_extracellular_region _h_4806_5-S1P1_S1P_Gi_1act_GNAI1_1act_S1P1_1act_S1P_extracellular_region _h_1707-NFAT1_3O_1act_nucleus _h_2216_2-RhoA_B_C_GDP_1ina_RhoC_GDP_v1 _h_2216_2-GTP_v1 _h_4443-PLA2_Group_4A_1act _h_15-EGFR_EGFR_EGF_EGF_GRB2_CBL_1act_coated_pit CalDAG_GEFI_cytoplasm-_h_4109 red _h_3790 (0) _h_664-Alpha_Synuclein__Aggregates_ _h_1874-MST4_1act_plasma_membrane grey _h_3884 (0) red _h_1701 (1) _h_1704-alpha9_beta1_Integrin_VCAM1_integral_to_membrane NF2_1act-_h_2623 green _h_6470 (0) grey _h_1140 (0) green _h_5510 (0) _h_623-p53_1u_cytoplasm _h_3160-GDP_v1 _h_3160-CDC42_GTP_WASP_1act_plasma_membrane grey _h_3888 (0) _h_5899_60-PI3K_beta_1act_plasma_membrane grey _h_4062 (0) grey _h_458 (3) _h_254_1-alpha6_beta4_Integrin_Laminin_14_3_3_hemidesmosome_alpha6_Integrin_Laminin_Gamma_Laminin_Alpha_YWHAG_beta4_integrin_1O_Laminin_beta1 grey _h_2772 (0) grey _h_6248 (0) grey _h_5085 (0) grey _h_1195 (0) green _h_1445 (1) green _h_4225 (2) green _h_4789 (1) _h_88-Syndecan_4_Tenascin_C LYN_cytoplasm-_h_3130_4 LYN_cytoplasm-_h_2345 GAP43_CaM-_h_28 green _h_984 (0) red _h_5683 (0) grey _h_5281 (0) grey _h_591 (0) grey _h_2928 (0) green _h_1106 (4) green _h_5151 (8) green _h_4427 (0) _h_499-GDP_v1 _h_499-RAC1_GTP_1act_cell_cell_junction _h_491-JAK1_1O_1act _h_490-FANCD2_FANCI_nucleus _h_493-NME1_1act_basolateral_plasma_membrane _h_492-COL18A1 _h_495-RB1_ID2_nucleus _h_494-ARF6_GTP_NME1_Tiam1_basolateral_plasma_membrane _h_496-KU70_SIRT1_nucleus _h_3477-GATA3_nucleus E_cadherin_beta_catenin_alpha_catenin_early_endosome-_h_6452 _h_3471-ATF1_1O_1act _h_3470-alpha4_beta7_Integrin_MAdCAM_1__dimer__integral_to_membrane _h_6255-alpha3_beta1_Integrin_Laminin_2_integral_to_membrane _h_3479-AFP _h_1878-alpha2_beta1_Integrin_Laminin_1_integral_to_membrane grey _h_6125_1 (0) grey _h_6125_2 (0) grey _h_6125_3 (0) grey _h_6125_4 (0) grey _h_6125_5 (0) grey _h_6125_6 (0) _h_1404_1-SMAD2_3_SMAD4_1act_nucleus_SMAD2_2O_1act_SMAD4 _h_5521-Receptors_internalized_by_Arf6_CIE _h_3961-Syndecan_2_Syntenin_PI_4_5_P2_plasma_membrane grey _h_3991_2 (0) VAMP2_1act-_h_2673 VAMP2_1act-_h_1250 grey _h_4661 (1) VAMP2_1act-_h_610 _h_141-IgHG3 _h_636-Syndecan_3_Src_Cortactin_growth_cone _h_147-beta3_Integrin _h_2168-IP3_Receptors_1act _h_1088-BRCA1_BACH1 _h_144-alpha2_beta1_Integrin_Type_IV_Collagen_integral_to_membrane _h_5028_1-MKK4_1act _h_149-alpha6_beta4_Integrin_Laminin_COL17A1_hemidesmosome _h_148-T_DHT_AR_PELP1_Src_plasma_membrane _h_639-S1P_S1P3_G12_G13 _h_638-COX2 grey _h_2531 (0) red _h_985 (0) red _h_10 (0) _h_2167-IL18 grey _h_4526 (0) _h_3262-alpha8_beta1_Integrin_Osteopontin_integral_to_membrane _h_442-Fra1 grey _h_3853_3 (0) _h_1162-IL4_IL4R_JAK1_IL2R_gamma_JAK3_FES_IRS2_1act_integral_to_membrane green _h_2478 (0) BoNT_A_precursor-_h_5152 green _h_6320 (0) SMO_Vitamin_D3_1ina_integral_to_membrane-_h_1064 _h_5899_64-PI3K_delta_1act_plasma_membrane grey _h_2272 (0) grey _h_1133 (0) _h_2637_21-PI3K_beta_1act_plasma_membrane _h_1959_1-VDR_Vit_D3_DNA _h_1959_1-RARs_RARs_DNA_9cRA_v1_RAR_alpha_DNA_rna_9cRA _h_1959_1-RARs_RARs_DNA_9cRA_v2_RAR_alpha_DNA_rna_ATRA _h_1959_2-RARs_RARs_DNA_9cRA_v1_Rar_gamma1_DNA_rna_9cRA _h_1959_2-VDR_Vit_D3_DNA _h_1959_2-RARs_RARs_DNA_9cRA_v2_Rar_gamma1_DNA_rna_ATRA _h_2637_22-PI3K_p110_beta_p55_gamma_1act_plasma_membrane _h_2614-c_Abl_Arg_1act _h_3264-RAF1_1O_3O_1act_plasma_membrane grey _h_5527 (0) p110_alpha-_h_2411 grey _h_1916 (0) _h_4442-DHT_AR_FOXA1_nucleus _h_3265-BMP9_ACTR2_Endoglin_ALK1__dimer__1act_integral_to_membrane _h_3265-FKBP12 _h_5899_65-PI3K_p110_alpha_p85_beta_1act_plasma_membrane _h_3004-PI3K_PIKE_GTP_1act_nucleus _h_3005-PEPCK _h_3002-5_LO_1O_1act Cyclin_B1_gene-_h_5945 Cyclin_B1_gene-_h_5610 Cyclin_B1_gene-_h_2208 Cyclin_B1_gene-_h_3965 Cyclin_B1_gene-_h_6070 Cyclin_B1_gene-_h_3845 Cyclin_B1_gene-_h_806 Cyclin_B1_gene-_h_2418 _h_3000-G_beta_gamma_HDAC5_1ina_cytoplasm _h_1036_115-alpha10_beta1_Integrin_endosome green _h_2423 (0) green _h_4898 (2) grey _h_3450 (2) green _h_2249 (4) green _h_5187 (2) grey _h_6174_2 (0) grey _h_6174_3 (0) green _h_5688 (4) grey _h_6174_1 (0) green _h_3280 (0) green _h_3054 (7) _h_2963 _h_2963 green _h_5374 (1) green _h_1550 (1) green _h_6047 (0) green _h_1688 (0) _h_2042-RAC1_GTP_betaPIX_1act_focal_adhesion _h_5525-PDK1_1act_plasma_membrane green _h_2186 (0) Alpha_SP22_1u_1act_1O_1O_cytoplasm-_h_778 grey _h_3849 (0) Actin_gene-_h_4967 _h_1036_112-alpha1_beta1_Integrin_endosome _h_3029-CDK5_1O green _h_2428 (0) green _h_196 (0) _h_5231-IFN_gamma_IFN_gammaR_JAK1_JAK1_JAK2_JAK2_1act LIMK1-_h_1059 LIMK1-_h_2659_1 LIMK1-_h_2342 LIMK1-_h_6338 _h_4440-FOXA1_nucleus PKACB-_h_2281_2 grey _h_2491 (0) grey _h_4646 (0) _h_5524-PSA _h_3630-PRDX3 green _h_135 (4) IRS2_Crk-_h_1816 green _h_3235 (5) _h_2195_5 _h_2195_1 _h_2385_2 _h_1487_2 _h_1487_4 _h_1487_3 _h_2195_6 STAT5B_1act_1O_cytoplasm-_h_2748 grey _h_4094 (0) green _h_260 (1) green _h_3950 (1) grey _h_4742 (0) PI_4_5_P2-_h_839 green _h_2027 (2) green _h_2396 (2) PI_4_5_P2-_h_6212 PI_4_5_P2-_h_4586 green _h_4203 (2) PI_4_5_P2-_h_176 grey _h_343 (0) grey _h_246 (0) Rad9-_h_2842 grey _h_4635 (0) grey _h_6394 (0) _h_5639-HGF_dimer__MET_dimer__GRB2_EPS15_1act_integral_to_membrane voltage_gated_calcium_channel_complex-_h_4739 voltage_gated_calcium_channel_complex-_h_6207 FAK_1ina-_h_2595 _h_3742-YY1_LSF_nucleus green _h_2923 (0) red _h_327 (2) green _h_6182 (1) green _h_4790 (1) red _h_3313 (8) red _h_3268 (8) _h_5635-Aurora_A_PP2A_1ina_centrosome green _h_3254 (1) _h_5899_69-PI3K_p110_beta_p85_beta_1act_plasma_membrane green _h_6295 (6) green _h_2124 (11) green _h_156 (0) _h_5498-Hec1_SPC24_kinetochore grey _h_4121 (0) grey _h_1253 (0) grey _h_2327 (2) grey _h_1251 (0) _h_5632-CCL2 _h_5631-MMP2 grey _h_4715 (0) grey _h_3749 (0) grey _h_3420 (0) grey _h_4806_5 (0) grey _h_4806_2 (0) grey _h_4806_3 (0) grey _h_4806_1 (0) grey _h_4806_4 (0) grey _h_1115 (0) grey _h_6176 (0) _h_3263_55-Ca2__v1 _h_3263_55-FGFR1b_FGF3_early_endosome _h_3263_55-alpha_catenin_cytoplasm _h_3263_55-p120_catenin_cytoplasm _h_3263_55-E_cadherin_beta_catenin_early_endosome_v2 _h_979-SMAD2_2O_1act_cytoplasm _h_5630-ROCK2_1act_plasma_membrane _h_2203-MCG10 _h_2202-IL4_extracellular_region _h_2201-PAG1_1ina _h_2200-Telomerase_AKT1_mTOR_p70S6K_1act _h_2207-IGFBP3 green _h_4831 (1) _h_2205-NOTCH1_precursor _h_2204-Alpha_Synuclein__Aggregates_ PLD_caveola-_h_1973 _h_2209-Osteocalcin _h_2208-Cyclin_B1 _h_5492-TSC2_1O_1act _h_1616-PAK2_1act CXCR4-_h_2183 grey _h_5488 (0) grey _h_487 (0) insulin_gene-_h_3378 insulin_gene-_h_39 grey _h_6015 (0) _h_3914-RasGAP_p62DOK_1act _h_3915-K5 40S_S6_ribosomal_protein-_h_5299 _h_5021-PDK1_1O_1act grey _h_4380 (0) Cyclin_A1_gene-_h_1625 _h_3912-TGFB_TGFBR2_TGFBR1_STRAP_SMAD7_1act_integral_to_membrane _h_3913-HES1_nucleus green _h_4598 (1) _h_5026-AS160_CaM_Ca2_ _h_4337-alpha1_beta1_Integrin_SCO_spondin_integral_to_membrane _h_19-T_DHT_AR_ARA70_nucleus _h_3918-proNGF__dimer__p75_NTR__Sortilin_MAGE_H1_1act_integral_to_membrane _h_3919-PAI_1 _h_4332-alpha11_beta1_Integrin_Type_I_Collagen_integral_to_membrane green _h_1125 (0) _h_1815-GPC1_Laminin_alpha1_1act_plasma_membrane grey _h_4614 (0) grey _h_3400_1 (0) grey _h_2374 (0) grey _h_3400_2 (0) N_WASP-_h_4906 grey _h_1670 (0) green _h_701 (0) _h_6288-VEGFR2__dimer__VEGFA__dimer__TSAd_1act_integral_to_membrane grey _h_2664 (0) _h_3308-SLUG _h_3709_3-RB1_E2F1_3_DP_HDAC3_RBBP4_nucleus_DP1_E2F1_RBBP4_RB1_HDAC3 _h_3709_2-RB1_E2F1_3_DP_HDAC3_RBBP4_nucleus_DP1_E2F3_RBBP4_RB1_HDAC3 _h_3709_1-RB1_E2F1_3_DP_HDAC3_RBBP4_nucleus_DP1_RBBP4_RB1_E2F2_HDAC3 _h_3400_2-Nephrin_NEPH1_podocin_NCK1_2_N_WASP_membrane_raft_NEPH1_2O_1act_NCK1_Nephrin_4O_1act_N_WASP_1act_podocin MAD4_gene-_h_3245 grey _h_6373 (0) _h_4233_5-Fyn_1O_1act_integral_to_membrane _h_1912-LEF1 eNOS-_h_5854 grey _h_1678 (0) _h_807_54-PI3K_p110_beta_p55_gamma_1act_plasma_membrane NOTCH2_heterodimer_CNTN1_1act_integral_to_membrane-_h_5444 _h_515_6-STAT5B__dimer__1act_nucleus PHD2_gene-_h_379 _h_515_5-STAT5A__dimer__active_1act_nucleus_v2 _h_515_3-STAT5B__dimer__1act_nucleus PAK1_betaPIX_PKL_NCK1_2_cytoplasm_v1_betaPIX_PAK1_NCK1_PKL-_h_6013_1 green _h_729 (0) green _h_4046 (1) green _h_5430 (0) _h_1917-PSA _h_6184-alphaM_beta2_Integrin_tPA_integral_to_membrane _h_6185-HRAS_SPRED2_1act _h_6186-proBDNF__dimer__p75_NTR__Sortilin_TRAF6_NRIF_1act_integral_to_membrane _h_6187-MAP3K11_1O_1O_1act_plasma_membrane _h_6180-BRCA1 _h_1914-IL8_extracellular_region _h_6182-LIF _h_6183-Mena_1act_cell_cell_junction _h_6188-MKK4_1O_1O_1act _h_6189-PDGF_BB_PDGFRB__dimer__1ina green _h_6149 (0) green _h_1480 (0) CENPE-_h_6331 Cyclin_D1_gene-_h_5039 Cyclin_D1_gene-_h_2456 Cyclin_D1_gene-_h_454 Cyclin_D1_gene-_h_4657 Cyclin_D1_gene-_h_3586 Cyclin_D1_gene-_h_1075 Cyclin_D1_gene-_h_911 Cyclin_D1_gene-_h_1232 Cyclin_D1_gene-_h_2877 Cyclin_D1_gene-_h_4197 Cyclin_D1_gene-_h_3746 Cyclin_D1_gene-_h_898 Cyclin_D1_gene-_h_3150 Cyclin_D1_gene-_h_3260 Cyclin_D1_gene-_h_17 Cyclin_D1_gene-_h_6275 Cyclin_D1_gene-_h_5714 Cyclin_D1_gene-_h_5636 Cyclin_D1_gene-_h_909 Cyclin_D1_gene-_h_4146 Cyclin_D1_gene-_h_5872 Cyclin_D1_gene-_h_6416 green _h_2761_2 (1) green _h_2761_3 (1) green _h_2761_1 (1) grey _h_5888 (0) grey _h_3534 (0) _h_3648-PGC1A _h_3649-uPA_uPAR_alphav_beta3_Integrin_1act_integral_to_membrane _h_3644-PPP2R4 grey _h_1433 (0) grey _h_3117 (0) grey _h_785 (0) _h_3640-IKK_complex_A20_cytoplasm grey _h_5346 (0) grey _h_3483 (0) _h_3642-TAK1_1act _h_4450-E2F1_nucleus _h_4450-proNGF__dimer__p75_NTR__Sortilin_MAGE_G1_1act_integral_to_membrane _h_1999 _h_1999 green _h_3390 (0) 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RAF1_BRAF_14_3_3_14_3_3_1act_plasma_membrane_v2_RAF1_1O_3O_YWHAG_BRAF_1O_2O-_h_4594_2 red _h_5610 (0) _h_5527-LAT_GRAP2_SLP76_VAV1_PI3K_Class_IA_1act_integral_to_membrane _h_5526-proBDNF__dimer__p75_NTR__Sortilin_1act_integral_to_membrane _h_419_1-ROCK_1act GLI3_1ina_cytoplasm-_h_413 green _h_2063 (1) green _h_5666 (0) green _h_2335 (0) green _h_3553 (0) green _h_6295 (0) _h_6048-CDK4 _h_515_4-STAT5A_B__dimer__1act_nucleus grey _h_4596_1 (0) grey _h_4596_2 (0) CABIN1-_h_3139 _h_807_55-PI3K_1act_plasma_membrane_v2 _h_2670 green _h_6344 (2) green _h_6498 (1) grey _h_1543 (0) grey _h_6229_5 (0) grey _h_730 (0) grey _h_3585 (0) _h_4447-Fyn_1O_1act_cytoplasm TMEM126A_gene-_h_2126 _h_5989-SIN3_HDAC_complex_NCoR1_nucleus TCF1_gene-_h_5743 grey _h_5823 (0) grey _h_2789 (0) _h_6324-LPP_1act_cell_cell_junction _h_55_1-NOTCH3_heterodimer_DSL_1act_integral_to_membrane_Delta_1_NOTCH3_N_terminal_fragment_NOTCH3_C_terminal_fragment _h_55_2-NOTCH3_heterodimer_DSL_1act_integral_to_membrane_JAG2_NOTCH3_N_terminal_fragment_NOTCH3_C_terminal_fragment _h_55_3-NOTCH3_heterodimer_DSL_1act_integral_to_membrane_JAG1_NOTCH3_N_terminal_fragment_NOTCH3_C_terminal_fragment _h_1823_2-uPA_uPAR_alphav_beta3_Integrin_Vitronectin_CK2_Nucleolin_1act_integral_to_membrane__alpha___alpha_prime___beta_2_CK2_1act_beta3_Integrin_uPA_chain_B_Vitronectin_Nucleolin_1p_uPA_long_chain_A_uPAR_alphav_Integrin _h_1823_3-uPA_uPAR_alphav_beta3_Integrin_Vitronectin_CK2_Nucleolin_1act_integral_to_membrane__alpha_2__beta_2CK2_1act_beta3_Integrin_uPA_chain_B_Vitronectin_Nucleolin_1p_uPA_long_chain_A_uPAR_alphav_Integrin green _h_3543 (0) KLRG1-_h_520 green _h_3130_8 (0) green _h_3130_5 (0) green _h_3130_4 (0) green _h_3130_7 (0) green _h_3130_6 (0) green _h_3130_1 (0) green _h_3130_3 (0) green _h_3130_2 (0) red _h_3101 (0) _h_2999-RGC32 _h_5015_5-YWHAZ _h_5015_5-KSR_1act_plasma_membrane _h_739_2-FOXM1B_Cbp_p300_1act_nucleus_FOXM1B_1O_p300 _h_2991-IL2R_beta_JAK1_LCK_SOCS3_SOCS2_1ina_integral_to_membrane _h_5015_6-KSR_1act_plasma_membrane _h_5015_6-YWHAQ _h_5762-STAT3__dimer__active_1act green _h_4586 (8) _h_5015_3-KSR_1act_plasma_membrane _h_5015_3-14_3_3_E _h_2994-CDC25C_1O _h_828-PSA _h_829-PSA grey _h_5986 (0) grey _h_6281 (0) grey _h_434 (0) Ku_Artemis_DNA_PKcs__dimer__Pol_Mu_XRCC4__dimer__Ligase_IV_site_of_double_strand_break_v1-_h_1192 grey _h_5381 (0) _h_820-BAX _h_821-ELK1_2O_1act_nucleus _h_822-PI3K_1act_plasma_membrane_v2 _h_824-HGF_dimer__MET_dimer__p52_SHC_GRB2_SOS1_1act_integral_to_membrane _h_2467 green _h_923 (1) _h_827-RAF1_1O_1O_1act_cytoplasm _h_2180-SRF_dimer__MAL_dimer__1act_nucleus green _h_5544 (2) grey _h_5393 (0) _h_2485_2-ETB_receptor_Endothelin_1_Gq_GTP_PLC_beta_1act_integral_to_membrane_ETB_ET1_PLC_beta_2_Gq_family_GTP_v1 _h_1510-Ephrin_B1_EPHB1_2_1act_integral_to_membrane_v2 _h_5984-IFN_gamma_extracellular_region SHMT1_gene-_h_5003 _h_739_1-FOXM1B_Cbp_p300_1act_nucleus_FOXM1B_1O_CBP _h_3862_3-Ephrin_A5_EPHA3_4_5_6_7_Src_Family_Kinases_1act_Ephrin_A5_EPHA3_4_5_6_7_Src_1act_1O _h_3862_2-Ephrin_A5_EPHA3_4_5_6_7_Src_Family_Kinases_1act_Ephrin_A5_EPHA3_4_5_6_7_LYN_1act_1O green _h_2210 (1) green _h_3825 (6) green _h_4529 (7) red _h_3816 (2) green _h_5674 (6) green _h_3015 (3) red _h_5418 (2) green _h_1271_1 (4) green _h_2190 (2) green _h_2750 (0) green _h_2752 (6) grey _h_4470 (0) green _h_86 (0) green _h_3307 (6) green _h_1271_2 (4) green _h_3993 (4) _h_3862_4-Ephrin_A5_EPHA3_4_5_6_7_Src_Family_Kinases_1act_Fyn_1O_1act_Ephrin_A5_EPHA3_4_5_6_7 _h_3302-T_DHT_AR_Cyclin_D3_CDK11_p58_nucleus Ephrin_B1_EPHB1_2_Src_Family_Kinases_1act_membrane_raft_Ephrin_B1_1O_EPHB1_2_Src_1act_1O-_h_1021_3 _h_4920-E2_ERA__dimer__AIB1_1act_nucleus _h_734-ILK_PINCH1_alpha_parvin_zyxin grey _h_3452 (0) _h_4924-EPOR_plasma_membrane _h_4925-Ephrin_A1_EPHA2_Tiam1_1act_integral_to_membrane grey _h_1189 (0) _h_735-p21CIP1 _h_4928-MARK4_1O_1act_cytoplasm _h_4929-VEGFR3_Fibronectin_alpha5_beta1_Integrin_1act_plasma_membrane _h_4698-CD95 green _h_2450 (24) LYZ_gene-_h_5187 grey _h_5853 (0) Cyclin_A-_h_5233 grey _h_4063 (0) grey _h_3349 (0) grey _h_3966 (0) grey _h_217 (0) grey _h_1821 (0) eIF4G1_gene-_h_6053 _h_2182-IL4_extracellular_region red _h_6017 (0) _h_732-Alpha_Synuclein_PLC_beta_2 grey _h_1051 (0) _h_6125_1-PRAS40_14_3_3_family_1ina_PRAS40_1O_YWHAS _h_6125_2-PRAS40_14_3_3_family_1ina_PRAS40_1O_14_3_3_E _h_6125_3-PRAS40_14_3_3_family_1ina_PRAS40_1O_YWHAQ _h_6125_4-PRAS40_14_3_3_family_1ina_YWHAB_PRAS40_1O _h_6125_6-PRAS40_14_3_3_family_1ina_PRAS40_1O_YWHAG _h_4623-BRCA2 red _h_3313 (7) red _h_3268 (7) _h_2183-CXCR4_1act_1O _h_4213-VEGFR2__dimer__VEGFA__dimer__integral_to_membrane _h_2034_1 grey _h_5461 (0) green _h_3941 (0) grey _h_4189 (0) PIP5K1B-_h_1624 PIP5K1B-_h_3959_3 PIP5K1A-_h_725 PIP5K1A-_h_4412 PIP5K1A-_h_3959_1 red _h_3668 (0) green _h_3825 (2) green _h_4529 (2) green _h_5674 (2) green _h_3015 (5) green _h_2750 (5) green _h_2752 (2) green _h_3307 (2) green _h_505 (0) _h_5609-RET51_GFRalpha1_GDNF_FRS2_membrane_raft _h_2756_3-SUV39H1 _h_2756_3-RB1_E2F1_3_DP_nucleus_v1_DP1_E2F3_RB1_2O _h_2184-HSP60_TLR2_TLR1_integral_to_membrane green _h_5380 (2) IL13RA2_gene-_h_5828 grey _h_1299 (0) grey _h_4302 (0) grey _h_5353 (0) grey _h_1780 (0) grey _h_1584 (0) grey _h_5547 (0) grey _h_5844 (0) grey _h_1758 (0) grey _h_500 (0) green _h_3454 (0) green _h_6089 (0) _h_6323-Alpha_Synuclein_1act_4O_cytoplasm grey _h_1000 (0) grey _h_3487 (0) _h_6434-ID2 _h_6435-NERF2 _h_6437-alpha4_beta7_Integrin_MAdCAM_1_integral_to_membrane FAK_1O_cytoplasm-_h_4342 _h_6431-VEGFR3_Type_I_Collagen_alpha2_beta1_Integrin_1act_plasma_membrane _h_6433-APC_C_CDC20_kinetochore red _h_136 (1) _h_6439-STAT4__dimer__JUN_1act_nucleus grey _h_3503 (0) grey _h_6035 (0) _h_764-PSEL grey _h_3248 (0) grey _h_3976 (0) red _h_6025 (1) AP1B1_gene-_h_954 AP1B1_gene-_h_1432 green _h_5388 (0) green _h_4677 (1) grey _h_4455 (0) green _h_770 (0) green _h_3106 (0) green _h_3716 (1) green _h_3843 (5) green _h_2461 (5) green _h_735 (3) A2M_gene-_h_1208 _h_1313_5-FOXO1_14_3_3_family_nucleus_v2_YWHAG_FOXO1_1O_2O red _h_110 (0) POMC_gene-_h_673 grey _h_3145 (0) _h_1271_2-Erk1_1O_1act_1O_cytoplasm green _h_191 (0) green _h_1300 (0) CPT1_gene-_h_5760 BUBR1_outer_kinetochore_of_condensed_chromosome-_h_5958 _h_4011_3-FGFR1_FGF_complex_Sef_endocytic_vesicle _h_1313_3-FOXO1_14_3_3_family_nucleus_v2_YWHAQ_FOXO1_1O_2O _h_762-TNFB_extracellular_region _h_4626-S1P_cytoplasm red _h_2912 (0) grey _h_2946 (0) green _h_4944 (0) _h_928-eIF4E _h_603-p53_2O_nucleus green _h_4495 (1) green _h_5806 (0) green _h_4683_9 (3) green _h_4683_8 (3) green _h_584 (21) green _h_4683_5 (3) green _h_4683_4 (3) green _h_4683_7 (3) green _h_4683_6 (3) green _h_4683_1 (3) green _h_4683_3 (3) green _h_4683_2 (3) green _h_445 (2) CD98_gene-_h_6002 _h_3141-paxillin_1act_1O_cytoplasm _h_2430-TXA2_TP_beta_beta_Arrestin2_endosome _h_2431-CCL2 grey _h_2438_2 (0) grey _h_2438_1 (0) _h_2435-GMCSF_GMR_alpha_CSF2RB_JAK2__dodecamer__SHC_SHIP_1act_integral_to_membrane _h_2436-EPO_EPOR__dimer__LYN _h_2436-LYN_1act_1O grey _h_5917 (0) _h_5051_79-PI3K_p110_alpha_p55_gamma_1act_plasma_membrane green _h_5590_1 (0) green _h_5590_2 (0) grey _h_2166_6 (0) grey _h_2166_5 (0) grey _h_2166_4 (0) grey _h_2166_3 (0) grey _h_2166_2 (0) grey _h_2166_1 (0) _h_5429-EPO_extracellular_region _h_5051_73-PI3K_p110_alpha_p85_beta_1act_plasma_membrane _h_5051_72-PI3K_beta_1act_plasma_membrane _h_5051_71-PI3K_1act_plasma_membrane_v2 _h_5051_70-PI3K_p110_beta_p85_beta_1act_plasma_membrane _h_5051_77-PI3K_p110_alpha_p85_beta_1act_plasma_membrane _h_5051_76-PI3K_p110_alpha_p55_gamma_1act_plasma_membrane _h_5051_75-PI3K_p110_beta_p55_gamma_1act_plasma_membrane _h_5051_74-PI3K_delta_1act_plasma_membrane grey _h_3561 (0) E_cadherin_beta_catenin_alpha_catenin_integral_to_membrane-_h_5232 green _h_1753 (1) green _h_691 (0) _h_760-PI3K_beta_1act_plasma_membrane green _h_3590 (1) green _h_241 (0) grey _h_5591 (0) green _h_1252 (0) green _h_704 (0) green _h_2031 (1) NEXT-_h_3788 grey _h_1252 (1) green _h_3235 (8) STAP1-_h_5588 green _h_3054 (15) _h_6430-Caspase_3_1ina _h_2434_59-PI3K_delta_1act_plasma_membrane HIC1_gene-_h_4355 HIC1_gene-_h_5076 PI3K_p110_beta_p55_gamma_1ina-_h_5051_5 PI3K_p110_beta_p55_gamma_1ina-_h_2434_2 PI3K_p110_beta_p55_gamma_1ina-_h_5051_6 PI3K_p110_beta_p55_gamma_1ina-_h_5051_26 PI3K_p110_beta_p55_gamma_1ina-_h_2434_46 PI3K_p110_beta_p55_gamma_1ina-_h_5051_62 PI3K_p110_beta_p55_gamma_1ina-_h_5051_63 PI3K_p110_beta_p55_gamma_1ina-_h_2434_6 PI3K_p110_beta_p55_gamma_1ina-_h_5051_41 PI3K_p110_beta_p55_gamma_1ina-_h_5051_35 PI3K_p110_beta_p55_gamma_1ina-_h_5051_37 PI3K_p110_beta_p55_gamma_1ina-_h_2434_19 PI3K_p110_beta_p55_gamma_1ina-_h_2434_54 PI3K_p110_beta_p55_gamma_1ina-_h_5051_31 PI3K_p110_beta_p55_gamma_1ina-_h_2434_75 PI3K_p110_beta_p55_gamma_1ina-_h_2434_67 PI3K_p110_beta_p55_gamma_1ina-_h_2434_73 PI3K_p110_beta_p55_gamma_1ina-_h_2434_58 green _h_4295 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_h_3263_40-FGFR1b_FGF1_early_endosome _h_3263_40-E_cadherin_beta_catenin_early_endosome_v2 _h_3263_40-p120_catenin_cytoplasm _h_5510-Ran_GTP_Exportin_1_HDAC1_cytoplasm grey _h_6104 (0) grey _h_5606 (0) _h_842-FASLG_FAS__trimer__FADD_FADD_RIP_1act_integral_to_membrane _h_843-GRAIL _h_791-ADA _h_4714-Alpha_Synuclein_PLD1 _h_4713-TNF_alpha_extracellular_region PI3K_p110_alpha_p85_beta_plasma_membrane-_h_807_79 PI3K_p110_alpha_p85_beta_plasma_membrane-_h_807_54 PI3K_p110_alpha_p85_beta_plasma_membrane-_h_807_73 PI3K_p110_alpha_p85_beta_plasma_membrane-_h_807_76 PI3K_p110_alpha_p85_beta_plasma_membrane-_h_807_40 PI3K_p110_alpha_p85_beta_plasma_membrane-_h_807_35 PI3K_p110_alpha_p85_beta_plasma_membrane-_h_807_16 PI3K_p110_alpha_p85_beta_plasma_membrane-_h_807_66 PI3K_p110_alpha_p85_beta_plasma_membrane-_h_807_12 _h_4710-KIT_integral_to_membrane _h_5447-dNp63g__tetramer__p14ARF_1ina_nucleus ALB_gene-_h_2320 _h_848-HIF1A_p14ARF_1ina_nucleolus _h_849-Dok_R_1O _h_4719-SOCS3 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_h_3439-E_cadherin_integral_to_membrane _h_3439-p120_catenin_cytoplasm _h_3439-gamma_catenin_1O_cytoplasm _h_807_56-PI3K_p110_beta_p55_gamma_1act_plasma_membrane _h_5935-sTNF_alpha_extracellular_region _h_3431-Ephrin_A5_EPHA5_caveola _h_2723-GATA1 _h_3437-NDRG2 _h_3436-MT1_MMP _h_2175_4-RARs_AIB1_Cbp_p300_PCAF_9cRA_1act_AIB1_PCAF_p300_RAR_alpha_9cRA red _h_2282 (0) _h_807_59-PI3K_delta_1act_plasma_membrane grey _h_5202 (0) grey _h_4826 (0) green _h_3730 (1) green _h_3083 (0) _h_5931-Ca2__cytoplasm MBN_gene-_h_2249 _h_6307-ID2 _h_5932-IL2_IL2R_alpha_beta_gamma_JAK1_LCK_JAK3_STAM1_2_1act_integral_to_membrane grey _h_6038 (0) grey _h_5055 (0) grey _h_799 (0) grey _h_524 (0) grey _h_2458 (0) _h_671-PTCH1_integral_to_membrane _h_670-alpha4_beta1_Integrin_Fibronectin_Paxillin_integral_to_membrane _h_673-POMC CA1_gene-_h_2040 _h_675-FASLG_FAS__trimer__Src_Syk_1act_integral_to_membrane _h_674-MYC_Max_HBP1_1ina_nucleus _h_677-alphaM_beta2_Integrin_P_Selectin_PSGL1 green _h_6422 (0) 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green _h_3276 (0) red _h_1559 (5) green _h_6455 (0) green _h_5504 (0) green _h_1928 (0) green _h_4340 (0) green _h_1891 (0) green _h_4594_2 (0) green _h_4594_3 (0) green _h_4594_1 (0) green _h_4594_6 (0) green _h_4594_4 (0) green _h_4594_5 (0) green _h_4740 (0) green _h_4495 (0) green _h_5846 (0) green _h_368 (0) Erk2_1O_1O_1act-_h_5332_1 green _h_3237 (1) green _h_4860 (1) green _h_1653 (0) green _h_658 (0) green _h_1390 (0) green _h_1672 (0) green _h_1011 (0) green _h_2520 (0) green _h_2769 (0) green _h_1170 (0) green _h_1230 (0) green _h_4391 (0) green _h_4643 (2) green _h_1290 (0) green _h_1471 (1) green _h_4376 (0) green _h_1188 (0) green _h_6274 (1) grey _h_5355_2 (0) green _h_4405 (0) green _h_4916 (0) green _h_2085 (1) _h_1282_1 green _h_1219_1 (0) green _h_933 (0) green _h_2539 (0) green _h_533 (0) green _h_4973 (0) green _h_6236 (0) green _h_6377 (0) green _h_3116 (0) grey _h_295 (0) grey _h_5355_1 (0) PIP5K1B_1ina_plasma_membrane-_h_5658 red _h_5280 (0) red _h_6 (0) RB1_E2F1_3_DP_nucleus_v1_DP1_E2F1_RB1_2O-_h_3475_2 RB1_E2F1_3_DP_nucleus_v1_DP1_E2F1_RB1_2O-_h_540_1 red _h_2444 (0) NEXT_1O_integral_to_membrane-_h_5538 grey _h_1581 (0) Acid_Sphingomyelinase-_h_3018 Acid_Sphingomyelinase-_h_721 _h_2544 Acid_Sphingomyelinase-_h_5424 red _h_800 (0) green _h_782 (0) grey _h_1920 (0) _h_1636_2-FGFR1_FGF_complex_Src_Cortactin _h_1636_3-FGFR1_FGF_complex_Src_Cortactin _h_1636_1-FGFR1_FGF_complex_Src_Cortactin _h_1636_6-FGFR1_FGF_complex_Src_Cortactin _h_1636_7-FGFR1_FGF_complex_Src_Cortactin _h_1636_4-FGFR1_FGF_complex_Src_Cortactin _h_1636_5-FGFR1_FGF_complex_Src_Cortactin _h_1636_8-FGFR1_FGF_complex_Src_Cortactin _h_1636_9-FGFR1_FGF_complex_Src_Cortactin green _h_5308 (2) grey _h_6491 (1) _h_4727-MIM_GLI1_1act_nucleus green _h_1507 (1) green _h_5341 (1) green _h_1372 (1) green _h_1271_1 (2) green _h_1271_2 (2) grey _h_5410_5 (0) grey _h_4839 (0) grey _h_254_5 (0) grey _h_2751_3 (0) grey _h_6096 (0) grey _h_925_5 (0) grey _h_3250_6 (0) grey _h_337 (0) grey _h_4371 (0) grey _h_118_5 (0) grey _h_3173_3 (0) grey _h_201_2 (0) grey _h_2084_3 (0) grey _h_6125_2 (0) grey _h_1426_4 (0) Mgp_gene-_h_4116 Mgp_gene-_h_2076 grey _h_5363 (0) green _h_3760 (1) green _h_5031 (5) grey _h_2892 (0) CaM-_h_1988 grey _h_6368 (0) green _h_919 (5) grey _h_117 (0) grey _h_3701 (0) green _h_2853 (2) red _h_4376 (2) grey _h_2312_1 (0) green _h_4454 (0) NKX3_gene-_h_852 NKX3_gene-_h_2960 _h_68-Alpha_Synuclein_1O_1u_1O_1act_cytoplasm _h_1180-MDM2 green _h_4122 (0) _h_1182-GATA1_Fog1_nucleus _h_3853_1-E2F1_3_DP_nucleus_DP1_E2F3 _h_3853_3-E2F1_3_DP_nucleus_DP1_E2F2 _h_3853_2-E2F1_3_DP_nucleus_DP1_E2F1 _h_4058_1-Erk2_1O_1O_1act grey _h_2924 (0) RAF1-_h_2137 RAF1-_h_5441 RAF1-_h_2794_1 RAF1-_h_5154 grey _h_5522 (0) RAF1-_h_4755 RAF1-_h_6198 grey _h_500 (0) grey _h_993 (0) grey _h_3764 (0) Cytochrome_C-_h_2405 Cytochrome_C-_h_1117 green _h_223 (0) green _h_2429 (1) grey _h_3088 (0) green _h_5232 (0) green _h_3373_1 (1) green _h_3373_2 (1) green _h_5503 (1) grey 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PI3K_p110_beta_p55_gamma_plasma_membrane-_h_807_70 PI3K_p110_beta_p55_gamma_plasma_membrane-_h_807_57 PI3K_p110_beta_p55_gamma_plasma_membrane-_h_807_42 PI3K_p110_beta_p55_gamma_plasma_membrane-_h_807_75 PI3K_p110_beta_p55_gamma_plasma_membrane-_h_807_45 grey _h_236 (0) green _h_194 (1) green _h_5056 (0) green _h_4786 (0) green _h_3674 (0) grey _h_4942 (0) grey _h_5310 (0) green _h_4906 (2) green _h_5373 (1) green _h_6187 (1) CDC42_GTP_1act_plasma_membrane-_h_936 green _h_308 (2) grey _h_1134 (0) grey _h_381 (0) green _h_1951 (3) green _h_3054 (4) grey _h_4607 (0) green _h_3707 (0) green _h_4462 (0) green _h_5950 (1) green _h_2121 (0) grey _h_5598 (0) green _h_4016 (0) green _h_1531 (1) grey _h_1512 (0) green _h_3968 (2) _h_4873-SIRT1_p300_nucleus MMP2_cytoplasm-_h_5768 green _h_937 (0) green _h_1533 (0) red _h_6357 (0) green _h_555_2 (1) green _h_555_1 (1) grey _h_912 (0) _h_880-PSA green _h_6263 (0) green _h_5977_1 (0) green _h_5977_2 (0) CEBPB-_h_6497 green _h_2859 (1) grey 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_h_866-BLIMP1 _h_867-VEGFR1__dimer__VEGFB186__dimer__1act_integral_to_membrane _h_860-Synphilin_1_1u _h_862-Cyclin_B1_CDK1_1ina green _h_3235 (26) HIP_55-_h_6321 green _h_5728 (0) green _h_5784 (0) BRG_1_nucleus-_h_5541 grey _h_6084 (0) grey _h_2127 (0) PTP1B-_h_946 PTP1B-_h_1723 green _h_3346 (0) green _h_1919 (0) green _h_3334 (0) PTP1B-_h_6058 green _h_2748 (0) grey _h_6484 (0) _h_5051_81-PI3K_1act_plasma_membrane_v2 _h_4656-SOCS3_2O_1act _h_4657-Cyclin_D1 _h_4654-VEGFR2_3_VEGFC__dimer__1act_integral_to_membrane _h_4655-RSK2_1O_1O MYL2-_h_2891 _h_4650-NOTCH1_heterodimer_NB_3_1act_integral_to_membrane Cytokeratin_18-_h_6074 _h_6013_1-PAK1_betaPIX_PKL_NCK1_2_cytoplasm_v2_PAK1_1act_betaPIX_NCK1_PKL _h_4659-HDAC1_Smad7_nucleus_v1 grey _h_2239_1 (0) grey _h_5509_3 (0) grey _h_5509_2 (0) grey _h_4127 (0) PER1_cytoplasm-_h_5479_1 grey _h_2783_1 (0) MHC_1A_gene-_h_5143 grey _h_1926 (0) sphingomyelin-_h_6401 sphingomyelin-_h_5255 _h_3895_3-FOXO1_14_3_3_family_1ina_cytoplasm_FOXO1_1O_4O_YWHAS _h_3895_2-FOXO1_14_3_3_family_1ina_cytoplasm_FOXO1_1O_4O_14_3_3_E _h_3895_1-FOXO1_14_3_3_family_1ina_cytoplasm_FOXO1_1O_4O_YWHAG grey _h_767 (0) CBL_plasma_membrane-_h_4232 _h_3895_5-FOXO1_14_3_3_family_1ina_cytoplasm_FOXO1_1O_4O_YWHAZ _h_3895_4-FOXO1_14_3_3_family_1ina_cytoplasm_YWHAB_FOXO1_1O_4O SM22_gene-_h_1034 _h_4524-SOCS3 TCR_CD3_MHC_II_CD4_LCK_ZAP_70_3BP2_1act_integral_to_membrane_v1-_h_551 green _h_1277 (10) _h_3126-RAP1A_GTP_1act _h_3126-GDP_v1 _h_5396 _h_1920-TNF_alpha_TNFR2__cleaved__TRAF1_TRAF2_1act_integral_to_membrane green _h_38 (2) _h_240-Ephrin_A1_EPHA2_integral_to_membrane _h_242-VEGFR2__dimer__VEGFA__dimer__IQGAP1_VE_cadherin_beta_catenin_alpha_catenin_1act_integral_to_membrane _h_243-E_cadherin_beta_catenin_alpha_catenin_cell_cell_junction green _h_3786 (0) _h_246-S1P_S1P5_G12_v1 green _h_6240 (0) _h_249-alpha4_beta1_Integrin_ADAM28_integral_to_membrane INCENP_gene-_h_174 grey _h_5668 (0) grey _h_26 (0) green _h_2724 (0) grey _h_5968 (0) green _h_4522 (0) NIK-_h_1323 Citron-_h_2096 Citron-_h_3530 PPM1J_gene-_h_3275 grey _h_5052 (0) _h_5565_1-JUNB_JUN_FOS_1act_nucleus_JUN_JUNB _h_179-RAB3GAP2_RIMS1_UNC13B WWP1_gene-_h_1035 grey _h_4493_6 (0) green _h_555_2 (8) grey _h_4751 (0) green _h_555_1 (8) green _h_1173_1 (0) green _h_1173_2 (0) green _h_3568 (2) grey _h_5710 (0) grey _h_1815 (0) green _h_5973 (1) grey _h_2599 (0) grey _h_2844 (0) grey _h_1615_3 (0) grey _h_1615_2 (0) grey _h_1615_1 (0) grey _h_2030 (0) grey _h_3732 (0) grey _h_2187 (0) grey _h_1561 (0) grey _h_2947 (0) grey _h_2357 (0) green _h_2595 (0) grey _h_3637 (0) grey _h_975 (0) _h_388_1-AR_T_DHT_plasma_membrane grey _h_4302 (0) grey _h_1780 (0) _h_173-Aurora_B_RasGAP_Survivin_1ina green _h_701 (8) green _h_3235 (7) _h_3385-TCR_CD3_MHC_II_CD4_LCK_ZAP_70_1act_integral_to_membrane _h_6479-EGR1 _h_3387-CD4_HIV_Nef_AP2_vacuolar_proton_transporting_V_type_ATPase_complex_early_endosome_v2 grey _h_6049 (0) GLI2_cytoplasm-_h_2988 GLI2_cytoplasm-_h_2704 grey _h_87 (0) _h_3925-alphav_beta3_Integrin_VEGFR2_VEGFA__dimer__integral_to_membrane green _h_3952 (24) SALL4_gene-_h_3727 SALL4_gene-_h_6000 _h_3382-ADM _h_6470-Ran_GTP_Exportin_1_HDAC4_cytoplasm _h_176-PI_3_4_5_P3_plasma_membrane _h_6472-netrin_1_DCC_FAK_Fyn_1act_integral_to_membrane_v3 _h_2726 _h_6474-WNT3A_LRP6_FZD5_DVL_Axin1_GSK3_1act_signalosome_v3 _h_3388-ILK_ELMO2 _h_6476-Gi_family_GTP_1act _h_6476-GDP_v1 _h_6476-GNB1_GNG2_1ina _h_177-PKC_beta2_1act _h_5927-KU_TER_nucleus _h_5926-Tie2_Ang1_SHP2_1act _h_5925-WAVE1_Sra1_Nap1_HSPC300_ABI2_1act_plasma_membrane _h_5924-CDC42_GDP_1ina_plasma_membrane _h_5923-p62DOK_1act_2O_plasma_membrane _h_5922-RASGRF1_1act_1O BRAF_14_3_3__dimer__1ina_cytoplasm_BRAF_1O_v1_YWHAZ-_h_921_4 _h_5920-VEGFR1_2__dimer__PLGF1__dimer__1act _h_300-SDF1_CXCR4_1act_integral_to_membrane BRAF_14_3_3__dimer__1ina_cytoplasm_BRAF_1O_v1_YWHAQ-_h_921_6 green _h_4631 (0) BRAF_14_3_3__dimer__1ina_cytoplasm_BRAF_1O_v1_YWHAS-_h_921_1 NF_kappa_B_RelA_1act_cytoplasm_v3-_h_2223 _h_1654 green _h_2702 (1) green _h_3814 (1) NF_kappa_B_RelA_1act_cytoplasm_v1-_h_2473 _h_485_3 _h_485_5 _h_485_2 _h_2069_1-LAT_GRAP2_SLP76_HPK1_HIP_55_CRK_family_1act_integral_to_membrane_LAT_10O_GRAP2_HPK1_1O_Crk_HIP_55_2O_SLP76_3O grey _h_2430 (1) _h_4521-GAB1_SHP2_PKA_eNOS_1act _h_3538_1-NKD2_DVL_plasma_membrane _h_3538_3-NKD2_DVL_plasma_membrane green _h_3054 (5) green _h_4567 (1) _h_5942-p53_1O_2O_nucleus grey _h_1861 (0) RasGAP_cytoplasm-_h_4471 _h_2093-Sortilin_TRAF6_NRIF_1act_integral_to_membrane _h_2093-p75_ICD green _h_2078 (0) IL5_extracellular_region_gene-_h_4959 IL5_extracellular_region_gene-_h_2128 IL5_extracellular_region_gene-_h_1132 green _h_1399 (0) green _h_3914 (0) grey _h_6001_2 (0) grey _h_6001_1 (0) green _h_3627 (3) _h_2597-mTORC1_PRAS40_DEPTOR_1ina_perinuclear_region_of_cytoplasm green _h_5217 (1) _h_2596-Cyclin_A SDF1_CXCR4_1ina_integral_to_membrane-_h_5720 green _h_3569 (0) green _h_4955 (0) green _h_5615 (0) grey _h_5665_2 (0) grey _h_5665_1 (0) grey _h_6326 (0) grey _h_5847 (0) grey _h_3669 (0) _h_5051_36-PI3K_p110_alpha_p55_gamma_1act_plasma_membrane _h_5051_35-PI3K_p110_beta_p85_beta_1act_plasma_membrane _h_5051_34-PI3K_p110_alpha_p55_gamma_1act_plasma_membrane NFATc_2O_1ina_11O_cytoplasm-_h_4749 _h_5051_32-PI3K_p110_beta_p55_gamma_1act_plasma_membrane _h_5051_31-PI3K_p110_delta_p85_beta_1act_plasma_membrane _h_3455_2-NFAT1_c_4_YWHAQ_1ina_cytoplasm_NFAT1_1ina_21O_cytoplasm_YWHAQ grey _h_3429 (0) grey _h_2343 (0) grey _h_138 (0) _h_5051_39-PI3K_beta_1act_plasma_membrane _h_5051_38-PI3K_p110_delta_p55_gamma_1act_plasma_membrane grey _h_4720 (0) _h_2894_2-FOXO1_3a_4_14_3_3_family_1ina_cytoplasm_FOXO1_3a_4_inactive_1ina_YWHAQ IL17F_gene-_h_5869 STAT3-_h_3428 STAT3-_h_3212 STAT3-_h_2739 STAT3-_h_397 grey _h_4981 (0) STAT3-_h_541 STAT3-_h_4343_1 STAT3-_h_5762 STAT2-_h_4718 STAT1-_h_3736 STAT1-_h_716 STAT1-_h_3627 STAT1-_h_4343_2 grey _h_1829 (0) _h_2069_2-LAT_GRAP2_SLP76_HPK1_HIP_55_CRK_family_1act_integral_to_membrane_LAT_10O_GRAP2_HPK1_1O_HIP_55_2O_CRKL_SLP76_3O grey _h_3912 (0) grey _h_2797 (0) grey _h_2029 (0) green _h_4635 (0) grey _h_3594 (0) grey _h_3353 (0) grey _h_159 (0) grey _h_811 (0) Smad3-_h_2741_1 Smad3-_h_5738 _h_2382-ARF6_GDP_GULP_ACAP1 _h_2381_2-FOXO3A_1O_1ina_2O_nucleus Insulin_responsive_Vesicles-_h_2524 _h_2387-E2_ERB__dimer__DAX_1_1act_nucleus _h_2384-sTNF_alpha_TNFR1A_TRADD_TRAF2_1act_endosome _h_2384-RIP_1u_1ina _h_4968-E_cadherin_Ca2__gamma_catenin_alpha_catenin_p120_catenin_cell_cell_junction _h_2388-alphav_beta3_Integrin_CD47_Type_IV_Collagen_integral_to_membrane _h_2389-Ku_Artemis_DNA_PKcs__dimer__POLL_site_of_double_strand_break _h_1928-BCL_X_L__1act _h_1928-BAD_1ina_1O _h_3260-Cyclin_D1 _h_4969-JNK2_1O_1O_1act grey _h_4493_3 (0) grey _h_1227 (0) grey _h_5204 (0) grey _h_5747_2 (0) grey _h_5747_3 (0) grey _h_4279 (0) grey _h_5747_1 (0) grey _h_47 (0) _h_4029 grey _h_3523 (0) grey _h_4147 (0) grey _h_5650 (0) grey _h_423 (0) _h_949-FOS grey _h_1815 (0) _h_1070-Cone_Transducin_1ina _h_2598-FOXO1_1O_2O_nucleus TUBA1A_gene-_h_2432 grey _h_4826 (0) grey _h_3626 (0) _h_5400-GDP_v1 _h_5400-GNB1_GNG2 _h_5400-Gs_family_GTP_1act_v1 grey _h_5133 (0) green _h_783 (0) green _h_284 (0) _h_1036_118-alpha5_beta1_Integrin_endosome HP1_alpha_gene-_h_1113 _h_3169-NPC_RanGAP1_SUMO1_RanBP2_Ubc9 grey _h_4309 (0) _h_2164-alpha9_beta1_Integrin_Factor_XIII_integral_to_membrane _h_2165-TIMELESS _h_941-DCC_NCK1_netrin_1_1act_integral_to_membrane _h_2160-DDX18 _h_2161-Aurora_A_Antizyme1 PDGF_BB_PDGFRB__dimer__GAB1_N_WASP_NCK1_2_1act_integral_to_membrane_v2_PDGFRB_11O_NCK2_PDGFB_v1_N_WASP_Gab1_1O-_h_2883_1 green _h_701 (26) _h_1129-RXRs_FXR_9cRA_MED1 _h_4075-NTAL_1act _h_4075-LAT_1act _h_5187-LYZ grey _h_4158_3 (0) green _h_3267 (2) _h_1120-PGC1_2O_1O_1act grey _h_656 (0) _h_1126-BoNT_A_Light_Chain_endosome _h_1125-Src_1act_1O _h_1124-Alpha_Synuclein_1act_1O_1O_cytoplasm _h_3263_58-Ca2__v1 _h_3263_58-FGFR1c_FGF5_early_endosome _h_3263_58-alpha_catenin_cytoplasm _h_3263_58-E_cadherin_beta_catenin_early_endosome_v2 _h_3263_58-p120_catenin_cytoplasm _h_3263_59-Ca2__v1 _h_3263_59-alpha_catenin_cytoplasm _h_3263_59-FGFR1b_FGF1_early_endosome _h_3263_59-E_cadherin_beta_catenin_early_endosome_v2 _h_3263_59-p120_catenin_cytoplasm beta_catenin_beta_TrCP1-_h_1839 green _h_335 (108) _h_3263_54-Ca2__v1 _h_3263_54-FGFR1b_FGF10_early_endosome _h_3263_54-alpha_catenin_cytoplasm _h_3263_54-E_cadherin_beta_catenin_early_endosome_v2 _h_3263_54-p120_catenin_cytoplasm grey _h_4371 (0) grey _h_2322 (0) grey _h_3058 (0) _h_3263_56-Ca2__v1 _h_3263_56-FGFR1c_FGF1_early_endosome _h_3263_56-alpha_catenin_cytoplasm _h_3263_56-E_cadherin_beta_catenin_early_endosome_v2 _h_3263_56-p120_catenin_cytoplasm _h_4071-PSA _h_3263_50-Ca2__v1 _h_3263_50-FGFR1c_FGF5_early_endosome _h_3263_50-alpha_catenin_cytoplasm _h_3263_50-E_cadherin_beta_catenin_early_endosome_v2 _h_3263_50-p120_catenin_cytoplasm _h_3263_51-Ca2__v1 _h_3263_51-FGFR1c_FGF6_early_endosome _h_3263_51-alpha_catenin_cytoplasm _h_3263_51-E_cadherin_beta_catenin_early_endosome_v2 _h_3263_51-p120_catenin_cytoplasm _h_3263_52-FGFR1c_FGF6_early_endosome _h_3263_52-Ca2__v1 _h_3263_52-alpha_catenin_cytoplasm _h_3263_52-p120_catenin_cytoplasm _h_3263_52-E_cadherin_beta_catenin_early_endosome_v2 grey _h_4560 (0) green _h_4586 (6) green _h_6161 (0) green _h_2325 (0) FADD_FADD_CASP8_CASP8_endosome-_h_3844 alpha5_beta1_Integrin_integral_to_membrane-_h_1036_62 grey _h_1349 (0) alpha5_beta1_Integrin_integral_to_membrane-_h_1036_24 grey _h_6351 (0) alpha5_beta1_Integrin_integral_to_membrane-_h_1036_117 grey _h_3429 (0) alpha5_beta1_Integrin_integral_to_membrane-_h_1036_76 alpha5_beta1_Integrin_integral_to_membrane-_h_1036_14 alpha5_beta1_Integrin_integral_to_membrane-_h_1036_91 alpha5_beta1_Integrin_integral_to_membrane-_h_1036_39 grey _h_1360 (0) grey _h_3659 (0) alpha5_beta1_Integrin_integral_to_membrane-_h_1249 alpha5_beta1_Integrin_integral_to_membrane-_h_1036_129 alpha5_beta1_Integrin_integral_to_membrane-_h_1036_26 alpha5_beta1_Integrin_integral_to_membrane-_h_1036_7 alpha5_beta1_Integrin_integral_to_membrane-_h_1036_102 alpha5_beta1_Integrin_integral_to_membrane-_h_1036_141 _h_3960-CDK2_Cyclin_E1_1ina E2F1_gene-_h_688 E2F1_gene-_h_3403 E2F1_gene-_h_6238 E2F1_gene-_h_136 E2F1_gene-_h_2754 MMP9_gene-_h_875 MMP9_gene-_h_2876 MMP9_gene-_h_3101 MMP9_gene-_h_1854 _h_3137-TAp73a _h_1366-IGF_1R_heterotetramer_IGF1_IRS1_caveola_v2 green _h_5375 (1) PFKFB3_gene-_h_3625 grey _h_6168 (0) grey _h_6015 (0) green _h_335 (127) grey _h_1424 (0) grey _h_2864 (0) MEK1_cytoplasm-_h_766_2 MEK1_cytoplasm-_h_4918_2 MEK1_cytoplasm-_h_4918_1 MEK1_cytoplasm-_h_2117 MEK1_cytoplasm-_h_1884_1 _h_6487-MIR130B_rna PAR1_active_1O_1O_integral_to_membrane-_h_4591 _h_1712-NR1D1 grey _h_2094 (0) _h_4203-ARF1_GTP_1act_plasma_membrane _h_2880-PKA_1act _h_6239-Ku_Artemis_DNA_PKcs__dimer__Pol_Mu_site_of_double_strand_break 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_h_2944_77-FGFR1b_FGF10_nucleus IKK_complex_v2-_h_451 _h_653-alphaX_beta2_Integrin_Fibrinogen_integral_to_membrane _h_652-Cathepsin_D _h_651-beta4_integrin _h_650-VAV1_1act_3O_plasma_membrane _h_656-GMCSF_GMR_alpha_CSF2RB_JAK2__dimer__integral_to_membrane _h_655-FOXO1_1O_1ina_1O _h_2628-EGFR_EGFR_EGF_EGF_p52_SHC_1act_endosome _h_807_7-PI3K_p110_alpha_p85_beta_1act_plasma_membrane _h_659-Fra2_ATF4_1act_nucleus _h_3290-ALOX15 _h_1036_113-alpha1_beta1_Integrin_endosome green _h_1510 (3) grey _h_919 (5) grey _h_3347 (7) _h_1133-VCAN_TLR2_TLR1_1act_integral_to_membrane ACAP1_cytoplasm-_h_4009 grey _h_4080 (0) _h_1581-RPA_RAD17_RFC2_5_9_1_1_1act_nucleus _h_3626-LIS1_CLIP170 _h_2434_64-PI3K_p110_alpha_p85_beta_1act_plasma_membrane green _h_5720 (3) green _h_5870 (0) green _h_4891 (0) grey _h_4269 (0) green _h_940 (0) green _h_6369 (0) green _h_6070 (0) green _h_6201 (0) beta1_Integrin_1O-_h_5315 grey _h_3653 (0) grey _h_6076 (0) GADD45B_1act_gene-_h_3446 grey _h_4102 (0) grey _h_5509_2 (0) grey _h_5509_1 (0) grey _h_4018 (0) grey _h_3147 (0) grey _h_4063 (0) grey _h_2557 (0) grey _h_4341 (0) grey _h_3552 (0) _h_4799_1-JUN_JUN_FOS_JAB1_1act_nucleus_JAB1_FOS_JUN_2O_2O green _h_4 (0) green _h_4950 (0) green _h_1706 (0) _h_3263_41-Ca2__v1 _h_3263_41-alpha_catenin_cytoplasm _h_3263_41-E_cadherin_beta_catenin_early_endosome_v2 _h_3263_41-FGFR1c_FGF4_early_endosome _h_3263_41-p120_catenin_cytoplasm _h_5302 NF_kappa_B2_p52_RelB_1act_cytoplasm-_h_5905 _h_5488-Syndecan_4_SDF1_CXCR4 T_bet_gene-_h_6504 T_bet_gene-_h_2580 T_bet_gene-_h_5603 _h_4799_2-JUN_JUN_FOS_JAB1_1act_nucleus_JUN_JAB1_JUN_2O_2O _h_3263_46-Ca2__v1 _h_3263_46-alpha_catenin_cytoplasm _h_3263_46-p120_catenin_cytoplasm _h_3263_46-FGFR1b_FGF2_early_endosome _h_3263_46-E_cadherin_beta_catenin_early_endosome_v2 _h_6237-BRCA2 green _h_5503 (0) _h_6460-NT3__dimer__TRKB_1act_extracellular_region green _h_4605 (2) grey _h_4382 (0) green _h_772 (0) green _h_2298 (0) green _h_5108 (1) green _h_4056 (0) green _h_6241 (1) green _h_4035 (0) green _h_4657 (4) green _h_6423 (2) green _h_5403 (2) SREBP1_gene-_h_2350 HMGIY_gene-_h_6386 _h_1069_1-HIF1A_ARNT_Cbp_p300_HDAC7_nucleus_HIF1A_HDAC7a_ARNT_p300 _h_1069_1-Cbp_p300_CITED2_1ina_CITED2_p300 _h_1069_1-HIF1A_ARNT_Cbp_p300_nucleus_HIF1A_ARNT_p300 _h_1069_2-Cbp_p300_CITED2_1ina_CITED2_CBP _h_1069_2-HIF1A_ARNT_Cbp_p300_HDAC7_nucleus_HIF1A_HDAC7a_ARNT_CBP _h_1069_2-HIF1A_ARNT_Cbp_p300_nucleus_HIF1A_ARNT_CBP _h_5487-Cytokine_rna grey _h_4014 (0) grey _h_121 (0) grey _h_5964_1 (0) grey _h_5964_2 (0) ERM_gene-_h_3068 ERM_gene-_h_2414 _h_6444 ASAP1_plasma_membrane-_h_260 _h_4095 _h_6111-Jnk1_1O_1act_1O_1O_cytoplasm _h_5482-Tiam1_1O_cell_cell_junction green _h_5728 (1) green _h_1797 (0) grey _h_889 (0) Yes_cytoplasm-_h_3130_7 MHF2_gene-_h_2287 MHF2_gene-_h_2716 grey _h_5100 (0) grey _h_3896 (0) grey _h_3265 (0) _h_2434_60-PI3K_p110_alpha_p85_beta_1act_plasma_membrane green _h_897 (0) green _h_5717 (0) green _h_392 (0) green _h_308 (1) DCP1B_gene-_h_4781 DCP1B_gene-_h_6332 green _h_4764 (0) PER1_2_cytoplasm_gene-_h_3710 ETS1_gene-_h_3979 ETS1_gene-_h_2537 green _h_1992 (0) green _h_4464 (2) green _h_3942 (1) green _h_135 (21) _h_5983-p21CIP1 green _h_3235 (22) green _h_5931 (19) CXCL10_CXCR3_integral_to_membrane-_h_5645 NTMIC_1O_integral_to_membrane-_h_618 _h_807_1-PI3K_p110_beta_p85_beta_1act_plasma_membrane _h_2931-EBAG9 _h_5025_2-FAK_Src_Yes_Fyn_RasGAP_1act_cell_leading_edge_Fyn_1O_1act_FAK_6O_1act_RasGAP NFAT1_c_4_1act_cytoplasm-_h_6404 _h_4578-Syndecan_4_GIPC green _h_3706 (5) grey _h_6282 (0) grey _h_292 (0) green _h_4586 (0) green _h_874 (2) _h_2595-FAK_1O_1act_cell_cell_junction _h_2594-uPAR_alphaM_beta2_Integrin_Fibrinogen_1act_integral_to_membrane _h_2593-ZCCHC12 _h_2592-E_cadherin_Ca2__beta_catenin_alpha_catenin_p120_catenin_cell_cell_junction_v3 _h_2591-p16INK4a _h_2590-alpha6_beta1_Integrin_Laminin_6_integral_to_membrane grey _h_1313_3 (0) grey _h_2075_6 (0) grey _h_4838_6 (0) grey _h_168_4 (0) grey _h_2894_2 (0) grey _h_2894_7 (0) grey _h_2894_6 (0) COL18A1_gene-_h_3296 COL18A1_gene-_h_492 COL18A1_gene-_h_3492 _h_2599-ATIII_GPC1_plasma_membrane _h_6291-ATF6_1p_1act _h_4987-GDP_v1 _h_4987-RALB_GTP_1act green _h_1010 (0) _h_6292-NF_kappa_B1_p50_RelA_1act_nucleus _h_6234-CDC42_GTP_IQGAP1_1act _h_439-MAP1B_1act _h_1533-FOXO4_1ina_nucleus green _h_5944 (1) _h_1713-HSP60_TLR4_MD2__dimer__1act_integral_to_membrane _h_1714-CD95 grey _h_677 (0) grey _h_631 (0) grey _h_4108 (0) grey _h_3486 (0) _h_1718-PIP5K1C_1act _h_1719-alphaM_beta2_Integrin_CTGF green _h_4295 (1) grey _h_929 (0) _h_3972-TSC1_TSC2_v2 grey _h_4472 (0) grey _h_2470 (0) _h_3976-Bam32_HPK1 Sphinganine-_h_3866 _h_3974-AP_24__cleaved__1act _h_4105_3-JUN_FOSNFAT1_c_4_1act_nucleus_c_Jun_2O_NFAT1_1O_7O_2s_1act_nucleus_FOS_1O_1O _h_3978-TRAILR4 _h_3979-ETS1 grey _h_4727 (0) grey _h_1239 (0) _h_2621-RB1_E2F4_DP_nucleus _h_657_3-TGFB_TGFBR2_betaglycan_1act_integral_to_membrane _h_2623-NF2_1ina_1O _h_2622-Plasmin_extracellular_region _h_2625-FOXO3A_1O_1ina_2O_nucleus _h_2624-CREB1_1act _h_3622-GNRH_extracellular_region _h_3620-RB1 _h_3621-PRAS40_1O _h_3621-mTORC1_1act _h_3621-DEPTOR_1p grey _h_3105 (0) _h_3627-STAT1__dimer__1act_v1 _h_3624-Moesin_1O _h_3625-PFKFB3 NFATc_1act_cytoplasm-_h_2171 _h_1384 K14_gene-_h_5822 K14_gene-_h_6496 K14_gene-_h_2337 K14_gene-_h_5402 _h_1110-ELF_SMAD3_1act_plasma_membrane green _h_4295 (9) green _h_2396 (1) _h_5485-INCENP_v1 _h_5486-STAT1__dimer__SHP2_1ina_nucleus_v1 grey _h_3073 (0) _h_5481-RET51_GFRalpha1_GDNF_Dok5 ACHE_gene-_h_6367 grey _h_684_1 (0) green _h_6443 (5) PKC_delta-_h_2784 grey _h_1347 (0) PKC_delta-_h_4516 PKC_delta-_h_4869 green _h_3071 (0) PKC_delta-_h_126 PKC_delta-_h_4490 grey _h_2152 (0) PKC_delta-_h_2186 green _h_77 (1) grey _h_2451 (0) green _h_3139 (1) Arp2_3_complex_v1-_h_1152 Arp2_3_complex_v2-_h_2316 _h_6298-VEGFR2__dimer__VEGFA__dimer__1ina_integral_to_membrane _h_6294-TCR_CD3_MHC_I_CD8_LCK_ZAP_70_CBL_ubiquitin_1ina_integral_to_membrane grey _h_1316 (0) _h_6297-VEGFR1_homodimer_VEGFA_homodimer_NCK1_1act_plasma_membrane _h_6290-MYC _h_4687 Gi_beta_gamma__1act_cytoplasm-_h_5460_1 Gi_beta_gamma__1act_cytoplasm-_h_5460_3 Gi_beta_gamma__1act_cytoplasm-_h_5460_2 Gi_beta_gamma__1act_cytoplasm-_h_5460_5 Gi_beta_gamma__1act_cytoplasm-_h_5460_4 _h_2434_18-PI3K_p110_beta_p55_gamma_1act_plasma_membrane Alpha_SP22_1O_1O_1act_cytoplasm-_h_858 grey _h_4711 (0)